CN114343189A - Health albumin pearl calcium oral liquid with immunoregulation function and preparation method thereof - Google Patents
Health albumin pearl calcium oral liquid with immunoregulation function and preparation method thereof Download PDFInfo
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- CN114343189A CN114343189A CN202210054077.1A CN202210054077A CN114343189A CN 114343189 A CN114343189 A CN 114343189A CN 202210054077 A CN202210054077 A CN 202210054077A CN 114343189 A CN114343189 A CN 114343189A
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- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 103
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Abstract
The invention discloses a health albumin pearl calcium oral liquid with an immunoregulation function. The invention adopts advanced enzymolysis technology to carry out enzymolysis on the egg white powder and the pearl powder into micromolecular polypeptide which is easy to absorb and utilize, more comprehensive amino acid and soluble calcium to obtain the enzymolysis ovalbumin liquid and the enzymolysis pearl calcium liquid, and the health-care oral liquid is prepared by taking the enzymolysis ovalbumin liquid and the enzymolysis pearl calcium liquid as effective components, thereby supplementing the synthetic raw materials and the calcium of protein required by a human body, increasing the nutrition of the human body, and enhancing and regulating the immunologic function of the human body.
Description
Technical Field
The invention belongs to the technical field of health-care product processing, and particularly relates to a health-care albumin pearl calcium oral liquid with an immunoregulation function.
Background
Albumin is a protein contained in human plasma, plays an important role in maintaining normal life activities, can provide nutrition supply, provide heat, protect and stabilize immunoglobulin for human bodies, and particularly needs to be supplemented additionally to people with low immune function, weak constitution and postoperative recovery period to meet body demands. The pearl contains abundant calcium and various amino acids essential to human body, and has the function of enhancing immunity, but the pearl powder prepared by the traditional physical method is not easy to be absorbed by human body.
The pearl powder and the protein powder of the macromolecules are subjected to enzymolysis treatment to obtain soluble calcium, micromolecular polypeptide and amino acid which are easy to be absorbed and utilized by human bodies. The enzymolysis stoste that obtains after the enzymolysis generally need be through filtration treatment, but the difficult filtrations of the small granule impurity that floats in the enzymolysis stoste are clean, and in liquid goods field, generally regard diatomaceous earth as the filter aid, adopt the diatomaceous earth filter to filter, can effectively improve the filter effect. But the filter jar internal arrangement multilayer of common diatomaceous earth filter scribbles the filtration disc of diatomaceous earth coating, uses a period back at the filter, because the filterable impurity particle of the filtration disc of front end is more, influences filter effect and logical water effect, needs to change the filtration disc of front end many times, and the change process is more loaded down with trivial details, the operation is complicated.
Disclosure of Invention
Based on the defects in the prior art, the invention adopts an advanced enzymolysis process to carry out enzymolysis on egg white powder (also called chicken protein powder) and pearl powder into micromolecular polypeptide which is easy to absorb and utilize, more comprehensive amino acid and soluble calcium, and prepares the health-care oral liquid by taking the enzymolysis ovalbumin liquid and the enzymolysis pearl calcium liquid as effective components, thereby supplementing protein and calcium for a human body, increasing the nutrition of the human body and enhancing and regulating the immune function of the human body.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
a health albumin pearl calcium oral liquid with an immunoregulation function comprises the following components in parts by weight:
300 parts of enzymolysis ovalbumin liquid;
50-200 parts of enzymolysis pearl calcium liquid;
50-80 parts of a sweetening agent;
30-50 parts of a sour agent;
namely, the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 1: 2-6: 1.
preferably, the sweetener comprises a protein sugar and a steviol glycoside;
preferably, the mass ratio of the protein sugar to the stevioside is 1: 1.
preferably, the acidulant comprises lactic acid.
Preferably, the preparation method of the health-care albumin pearl calcium oral liquid with the immunoregulation function comprises the following components in parts by weight:
300 parts of enzymolysis ovalbumin liquid;
50-200 parts of enzymolysis pearl calcium liquid;
50-80 parts of a sweetening agent;
30-50 parts of a sour agent;
the preparation method comprises the following preparation steps:
s1, preparing an enzymolysis ovalbumin solution;
s2, preparing an enzymolysis pearl calcium solution;
s3, mixing the enzymatic hydrolysis egg white protein liquid, the enzymatic hydrolysis pearl calcium liquid, the sweetening agent and the sour agent according to the weight parts, and dissolving and uniformly dispersing to obtain the health albumin pearl calcium oral liquid with the immunoregulation function;
preferably, the sweetener comprises a protein sugar and a steviol glycoside; the mass ratio of the protein sugar to the stevioside is 1: 1;
the sour agent comprises lactic acid.
Preferably, the preparation of the enzymatic egg albumin liquid comprises the following steps:
(1) adding egg white powder into pure water, heating at 100 deg.C, stirring for 10-20min, and aging;
(2) after the curing is finished and the temperature is cooled to 45-55 ℃, neutral protease is added for the first time, and the mixture is kept at 45-55 ℃ and stirred for 8-10h for enzymolysis reaction;
(3) adding neutral protease for the second time, and stirring at 45-55 deg.C for 8-10h to perform enzymolysis reaction;
(4) after the enzymolysis is finished, heating to 85-90 ℃ for enzyme deactivation treatment;
(5) cooling to 45-55 ℃ after enzyme deactivation is finished to obtain an enzymolysis stock solution A;
(6) mixing the enzymolysis stock solution A with diatomite, soaking for 0.5-1h, and filtering to obtain clear enzymolysis solution B;
(7) concentrating the enzymolysis solution B under reduced pressure at 65-80 deg.C and vacuum degree of-0.08-0.06 MPa to 40% -60% of the volume of the enzymolysis solution B to obtain enzymolysis ovalbumin solution;
wherein the weight of the added pure water is 20-30 times of the weight of the egg white powder; the total amount of the added neutral protease is 5 to 10 percent of the weight of the egg white powder; the amount of the neutral protease added for the first time accounts for 60-80% of the total amount of the neutral protease; the amount of the neutral protease added for the second time accounts for 20-40% of the total amount of the neutral protease; the dosage of the diatomite is 1% -3% of the total amount of the enzymolysis stock solution A.
Preferably, the preparation of the enzymatic hydrolysis pearl calcium solution comprises the following steps:
(1) heat treating Margarita in hot air circulation oven at 100 deg.C for 15-25min, and naturally cooling;
(2) pulverizing heat-treated Margarita into 60-80 mesh Margarita calcium powder;
(3) adding pearl calcium powder into pure water, adding lactic acid twice, adding lactic acid for the first time, continuously stirring for 50-60min, adding lactic acid for the second time, and continuously stirring for 50-60 min;
(4) heating to 70-75 deg.C, and stirring to dissolve Margarita calcium powder;
(5) cooling to 45-55 ℃, adding a calcium hydroxide solution to adjust the pH value of the feed liquid to 6.5-7.0, and obtaining acidolysis solution after acidolysis;
(6) adding neutral protease into the material liquid after the acidolysis, and carrying out enzymolysis by keeping the temperature at 45-55 ℃ and stirring for 8-10 h;
(7) after the enzymolysis is finished, heating to 85-90 ℃ for enzyme deactivation treatment;
(8) after enzyme deactivation is completed and cooling is performed, obtaining enzymolysis stock solution C;
(9) mixing the enzymolysis stock solution C with diatomite, soaking, and filtering to obtain clear enzymolysis solution D;
(10) concentrating the enzymolysis solution D under reduced pressure at 65-80 deg.C and vacuum degree of-0.08-0.06 MPa to 40% -60% of the volume of the enzymolysis solution D to obtain enzymolysis pearl calcium solution.
Wherein the weight of the pure water is 25-35 times of the weight of the pearl calcium powder; the total amount of the added lactic acid is 3-6 times of the weight of the pearl calcium powder; the amount of the lactic acid added for the first time accounts for 40-60% of the total amount of the lactic acid; the amount of the lactic acid added for the second time accounts for 40-60% of the total amount of the lactic acid; the amount of the added neutral protease is 5 to 10 percent of the weight of the pearl calcium powder; the dosage of the diatomite is 1% -3% of the total amount of the enzymolysis stock solution C.
The invention has the following functions:
the egg albumin is hydrolyzed into bioactive peptides such as egg albumin antioxidant peptide and the like under the action of neutral protease (incision enzyme), the antioxidant peptide is nonapeptide consisting of tyrosine, alanine, glutamic acid, arginine, proline, isoleucine and tyrosine, and has the functions of eliminating redundant free radicals in an organism and improving the anti-aging and disease-resistant capabilities of the organism.
The pearl powder contains more than 90 wt% of carbonate (mainly calcium carbonate) and 18 amino acids such as cysteine, alanine, glutamic acid, serine, valine, etc., wherein 7 amino acids are essential for human body; also contains trace elements, and can enhance immunity. Through acidolysis treatment, not only can the calcium carbonate be dissolved to form soluble organic calcium, and the trace elements are converted into soluble trace elements, but also the protein, polypeptide substances and amino acids embedded by the calcium carbonate in the pearl can be released; by further enzymolysis treatment, the protein and polypeptide can be further hydrolyzed to form small molecular polypeptide and amino acid. The amino acid has very important physiological action on human body, can regulate the endocrine of human body, and can effectively improve the activity of T, B lymphocytes in the immune system of human body, thereby enhancing the immune disease resistance; the pure natural calcium in the pearl is converted into soluble organic calcium, so that the pearl calcium is safe and healthy, has high digestibility, can meet the normal requirement of a human body on calcium, maintains the normal physiological state of cells, and makes the body strong and powerful; the synergistic effect of various amino acids and trace elements plays a role in soothing and calming the brain center, and cells which are over-excited to cause fatigue can be nourished after being absorbed by a human body, so that the sleep can be effectively improved.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention is prepared by taking the enzymolysis ovalbumin liquid and the enzymolysis pearl calcium liquid as effective components, is rich in micromolecule polypeptide which is easy to absorb and utilize, more comprehensive amino acid, soluble calcium and other various beneficial trace elements, can effectively supplement protein, calcium and other trace elements required by human body, increases the nutrition of the human body, and enhances and regulates the immune function of the human body.
2. When the enzymatic hydrolysis pearl calcium solution is prepared, firstly, the calcium carbonate in the pearl calcium powder is dissolved by the lactic acid, insoluble calcium which is not easy to be absorbed by a human body is converted into soluble calcium, other trace elements are also converted into soluble calcium, and protein, polypeptide substances and amino acid embedded by the calcium carbonate are released, then, the enzymatic hydrolysis reaction is carried out to further hydrolyze the protein and the polypeptide with larger molecular weight to completely form water-soluble micromolecule polypeptide and amino acid, and the enzymatic hydrolysis pearl calcium solution containing all nutrient active substances of the pearl is obtained, so that the pearl is fully utilized, meanwhile, the acidity of the lactic acid is relatively weaker, the reaction is mild, and other nutrient substances cannot be damaged.
3. The lactic acid is used as the sour agent, so that the sour agent is unique in sour taste, moderate and moderate in sour taste, has a strong antibacterial effect, can achieve the effects of preventing corrosion, preserving freshness and prolonging the shelf life, does not need to additionally add a preservative into the product, and is healthy and safe.
4. According to the invention, when the enzymolysis ovalbumin liquid and the enzymolysis pearl calcium liquid are prepared, the diatomite is used as a filter aid, and the particles of the diatomite have minuteness and porosity, so that impurities such as suspended particles in the enzymolysis liquid can be adsorbed, and the filtering effect and efficiency are improved.
Drawings
FIG. 1 is a flow diagram of a manufacturing process of the present invention;
FIG. 2 is a schematic diagram of the overall three-dimensional structure of the diatomite filter of the present invention;
FIG. 3 is a schematic view of the whole internal cross-sectional three-dimensional structure of the diatomite filter of the present invention;
FIG. 4 is a schematic view of the movable part of the diatomite filter in a sectional perspective view;
FIG. 5 is a schematic perspective view of a driving assembly of the diatomite filter according to the present invention;
FIG. 6 is a schematic perspective view of the movable filter assembly and the stirring paddle of the diatomite filter according to the present invention;
FIG. 7 is a schematic perspective view of a portion of the stirring blade of the diatomite filter according to the present invention;
FIG. 8 is a schematic perspective view of a part of the residue discharge assembly of the diatomite filter according to the present invention.
In the figure: 1. a filter vat; 11. installing a cover; 12. a connecting pipe; 14. supporting legs; 15. a liquid outlet; 2. a stock solution barrel; 3. a water pump; 4. a movable member; 41. a movable plate; 42. a through hole; 43. A first rubber sheet; 44. a limit convex ring; 45. a pressure detection sensor; 46. a rubber ring; 5. Moving the filter assembly; 51. moving the diatomite filter plate; 52. a second rubber sheet; 6. a drive assembly; 61. a connecting rod; 611. a lock nut; 612. a limiting bump; 62. a multi-stage hydraulic cylinder; 63. a connecting plate; 64. a spring; 65. a linkage plate; 7. a stirring paddle; 71. a fastener; 72. A connecting ring; 73. a wedge-shaped tooth socket; 74. wedge-shaped teeth; 75. fixing the rod; 76. a fixing plate; 77. a wedge-shaped convex ring; 8. fixing a diatomite filter plate; 9. a slag discharge assembly; 91. a sealing cover; 92. grooving; 93. a sealing plate; 94. and a locking part.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Preparing an enzymolysis ovalbumin solution:
(1) adding egg white powder into pure water, heating at 100 deg.C, stirring for 15min, and aging;
(2) after the curing is finished and the temperature is cooled to 50 ℃, adding neutral protease for the first time, keeping the temperature at 45-50 ℃ and stirring for 8 hours to carry out enzymolysis reaction;
(3) adding neutral protease for the second time, and stirring at 45-50 deg.C for 8 hr to perform enzymolysis reaction;
(4) after the enzymolysis is finished, heating to 90 ℃ for enzyme deactivation;
(5) cooling to 45-50 ℃ after enzyme deactivation is finished to obtain an enzymolysis stock solution A;
(6) mixing the enzymolysis stock solution A with diatomite, soaking for 0.5h, and filtering to obtain clear enzymolysis solution B;
(7) concentrating the enzymolysis solution B at 65-70 deg.C under vacuum degree of-0.08-0.06 MPa under reduced pressure to 40% of the volume of the enzymolysis solution B to obtain enzymolysis ovalbumin solution;
wherein the weight of the added pure water is 28 times of that of the egg white powder; the total amount of the added neutral protease is 8 percent of the weight of the egg white powder; the amount of the neutral protease added for the first time accounts for 70% of the total amount of the neutral protease; the amount of the neutral protease added for the second time accounts for 30% of the total amount of the neutral protease; the dosage of the diatomite is 1.2 percent of the total amount of the enzymolysis stock solution A.
Example 2
Preparing enzymolysis pearl calcium solution:
(1) heat treating Margarita in hot air circulation oven at 100 deg.C for 20min, and naturally cooling;
(2) pulverizing the heat-treated pearl into 60-mesh pearl calcium powder;
(3) adding pearl calcium powder into pure water, adding lactic acid twice, adding lactic acid for the first time, and continuously stirring for 60min, adding lactic acid for the second time, and continuously stirring for 60 min;
(4) heating to 70 deg.C, and stirring to dissolve Margarita calcium powder;
(5) cooling to 50 ℃, adding a calcium hydroxide solution to adjust the pH value of the feed liquid to 6.5-7.0 to obtain acidolysis solution after acidolysis;
(6) adding neutral protease into the material liquid after the acidolysis, and carrying out enzymolysis by keeping the temperature at 45-50 ℃ and stirring for 8 h;
(7) after the enzymolysis is finished, heating to 90 ℃ for enzyme deactivation;
(8) after enzyme deactivation is completed and cooling is performed, obtaining enzymolysis stock solution C;
(9) mixing the enzymolysis stock solution C with diatomite, soaking for 1h, and filtering to obtain clear enzymolysis solution D;
(10) concentrating the enzymolysis solution D at 65-70 deg.C under vacuum degree of-0.08-0.06 MPa under reduced pressure to 40% of the volume of the enzymolysis solution D to obtain enzymolysis pearl calcium solution;
wherein the weight of the added pure water is 30 times of that of the pearl calcium powder; the total amount of the added lactic acid is 4.8 times of the weight of the pearl calcium powder; the amount of the first added lactic acid accounts for 50% of the total amount of the lactic acid; the amount of the second addition of lactic acid accounts for 50% of the total amount of lactic acid; the amount of the added neutral protease is 8 percent of the weight of the pearl calcium powder; the dosage of the diatomite is 1.2 percent of the total amount of the enzymolysis stock solution C.
Neutral protease in examples 1 and 2 was supplied by beijing baiolabockiu technology ltd, and product specifications were: 20 ten thousand U/g.
Example 3
A health albumin pearl calcium oral liquid with an immunoregulation function comprises the following components in parts by weight:
100 parts of enzymolysis ovalbumin liquid, 200 parts of enzymolysis pearl calcium liquid, 25 parts of protein sugar, 25 parts of stevioside and 30 parts of lactic acid;
the preparation method comprises the following steps:
uniformly mixing the enzymolysis ovalbumin liquid, the enzymolysis pearl calcium liquid, the protein sugar, the stevioside and the lactic acid according to the weight parts to obtain the albumin pearl calcium oral liquid;
wherein the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 1: 2.
example 4
A health albumin pearl calcium oral liquid with an immunoregulation function comprises the following components in parts by weight:
300 parts of enzymolysis ovalbumin liquid, 50 parts of enzymolysis pearl calcium liquid, 40 parts of protein sugar, 40 parts of stevioside and 50 parts of lactic acid;
the preparation method is the same as that of example 3;
wherein the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 6: 1.
example 5
A health albumin pearl calcium oral liquid with an immunoregulation function comprises the following components in parts by weight:
200 parts of enzymolysis ovalbumin liquid, 100 parts of enzymolysis pearl calcium liquid, 35 parts of protein sugar, 35 parts of stevioside and 40 parts of lactic acid;
the preparation method is the same as that of example 3;
wherein the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 2: 1.
example 6
A health albumin pearl calcium oral liquid with an immunoregulation function comprises the following components in parts by weight:
280 parts of enzymolysis ovalbumin liquid, 70 parts of enzymolysis pearl calcium liquid, 38 parts of protein sugar, 37 parts of stevioside and 45 parts of lactic acid;
the preparation method is the same as example 3.
Wherein the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 4: 1.
the enzymatic egg white protein solution of examples 3-6 was the enzymatic egg white protein solution prepared in example 1; the enzymatic hydrolyzed pearl calcium solution is the enzymatic hydrolyzed pearl calcium solution prepared in example 2.
Comparative example 1
Compared with the example 3, the enzymolysis ovalbumin liquid is not added in the comparative example 1, the difference is complemented by the enzymolysis pearl calcium liquid, and other conditions are not changed.
Comparative example 2
Compared with the example 3, the enzymolysis pearl calcium liquid is not added in the comparative example 1, the difference is complemented by the enzymolysis ovalbumin liquid, and other conditions are not changed.
Comparative example 3
Compared with the embodiment 4, the enzymolysis pearl calcium liquid in the comparative example 3 is changed to 37.5 parts, namely the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 8: 1, other conditions were unchanged.
Comparative example 4
Compared with the embodiment 3, the enzymolysis ovalbumin liquid in the comparative example 4 is changed into 50 parts, namely the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is 1: 4, other conditions were unchanged.
Comparative example 5
In comparison with example 3, in comparative example 5, lactic acid was not added, and other conditions were not changed.
Example 7
The embodiment discloses a diatomite filter, and the enzymolysis ovalbumin liquid prepared in the embodiment 1 and the enzymolysis pearl calcium liquid prepared in the embodiment 2 are both subjected to filtration treatment of enzymolysis stock solution in the equipment.
As shown in fig. 2-8, the diatomite filter comprises a filter vat 1, a raw liquid vat 2 is arranged on one side of the filter vat 1, the filter vat 1 is connected with the raw liquid vat 2 through a water pump 3, a movable part 4 is arranged above the inner cavity of the filter vat 1, and the sealing degree of the top of the filter vat 1 is changed when the movable part 4 moves up and down; the middle part of the filter barrel 1 is provided with a movable filter component 5 for primarily filtering the enzymolysis stock solution; the moving filter assembly 5 comprises a moving diatomite filter plate 51; the top of the filter barrel 1 is provided with a driving component 6, the driving component 6 comprises a connecting rod 61, and the driving component 6 is connected with the movable filter component 5 through the connecting rod 61; the bottom of the connecting rod 61 is provided with a stirring paddle 7 above the movable filtering component 5, and the stirring paddle 7 is provided with a clamping piece 71, so that the stirring paddle 7 is separated from the clamping piece 71 when moving upwards, and the stirring paddle 7 can rotate independently; the bottom of the filter barrel 1 is provided with a fixed diatomite filter plate 8, and the fixed diatomite filter plate 8 is used for carrying out secondary filtration on the enzymolysis stock solution; a residue discharging component 9 is arranged at the position of the outer side of the filter barrel 1, which is opposite to the upper part of the fixed diatomite filter plate 8.
Further, 1 top of filter vat is provided with installation lid 11, installation lid 11 one side is connected with water pump 3 through connecting pipe 12, drive assembly 6 is located 11 top middle parts of installation lid, 1 below of filter vat is provided with supporting leg 14, 1 bottom of filter vat is provided with liquid outlet 15, utilize water pump 3 through connecting pipe 12 with the enzymolysis stoste suction filter vat 1 in stoste bucket 2 in, and make diatomaceous earth and enzymolysis stoste mix, adsorb earlier and clear away the debris in the enzymolysis stoste.
Further, the movable part 4 comprises a movable plate 41, a plurality of through holes 42 are arranged on the movable plate 41, a first rubber sheet 43 is arranged above the movable plate 41, two limit convex rings 44 are arranged on the side wall of the upper portion in the filter barrel 1, the movable part 4 is positioned between the two limit convex rings 44, a pressure detection sensor 45 is arranged on the outer side of the filter barrel 1 and below the limit convex rings 44, the pressure detection sensor 45 is used for detecting the pressure between the movable part 4 and the movable filter component 5, the middle portions of the movable plate 41 and the first rubber sheet 43 are in interference connection with the connecting rod 61 through a rubber ring 46, the movable plate 41 is connected with the first rubber sheet 43 through the rubber ring 46, and the rubber ring 46 is in interference connection with the connecting rod 61, so that when the connecting rod 61 moves up and down, the movable part 4 can be driven to move up and down, and under the action of the limit convex rings 44, the movable part 4 can only move up and down between the limit convex rings 44, when the connecting rod 61 drives the moving part 4 to move upwards, the movable plate 41 pushes the first rubber sheet 43 to move upwards at the bottom of the first rubber sheet 43 and moves to the position of the limiting convex ring 44 at the upper side, so that the peripheral side of the first rubber sheet 43 is in complete fit contact with the inner wall of the filter barrel 1, and the upper part of the filter barrel 1 is tightly plugged; when the connecting rod 61 drives the moving part 4 to move downwards, the movable plate 41 pulls the first rubber sheet 43 downwards at the bottom of the first rubber sheet 43 through the rubber ring 46, and moves to the position of the limiting convex ring 44 on the lower side, because the first rubber sheet 43 contacts with the inner wall of the filter barrel 1, under the action of friction force between the first rubber sheet 43 and the inner wall of the filter barrel 1, the peripheral side of the first rubber sheet 43 is partially separated from the inner wall of the filter barrel 1 to form a corrugated gap, and then the introduced enzymolysis stock solution enters the lower part of the moving part 4 to be mixed.
Further, remove filtering component 5 and still include second sheet rubber 52, second sheet rubber 52 is located and removes diatomaceous earth filter 51 bottom, remove diatomaceous earth filter 51 and second sheet rubber 52 cup joint at connecting rod 61 lower extreme, connecting rod 61 bottom threaded connection has lock nut 611, connecting rod 61 is located lock nut 611 top and is provided with spacing lug 612, remove filtering component 5 and be located between lock nut 611 and the spacing lug 612, utilize connecting rod 61 to drive and remove diatomaceous earth filter 51 and reciprocate: when the movable diatomite filter plate 51 moves upwards, the movable diatomite filter plate 51 drives the second rubber sheet 52 at the bottom of the movable diatomite filter plate to move upwards together, the peripheral side of the second rubber sheet 52 is separated from the inner wall of the filter barrel 1 due to the friction force between the second rubber sheet 52 and the inner wall of the filter barrel 1 during moving, a corrugated gap is formed, the movable piece 4 also moves upwards at the moment, a sealing piece is formed to seal the top of the filter barrel 1, a syringe principle is formed between the movable piece 4 and the movable filter component 5, and then the enzymolysis stock solution between the movable piece 4 and the movable filter component 5 can be quickly discharged towards the lower part of the movable filter component 5; similarly, when the movable diatomite filter plate 51 moves downwards, the movable diatomite filter plate 51 pushes the second rubber sheet 52 at the bottom of the movable diatomite filter plate to move downwards, so that the peripheral side of the second rubber sheet 52 is completely matched with the inner wall of the filter barrel 1, the movable member 4 also moves downwards at the moment, the peripheral side of the first rubber sheet 43 is separated from the inner wall of the filter barrel 1 to form a corrugated gap, an injector principle is formed between the movable filter assembly 5 and the movable member 4 at the moment, and when the movable filter assembly 5 moves downwards, the enzymolysis stock solution above the movable member 4 is sucked between the movable filter assembly 5 and the movable member 4 from the corrugated gap formed at the peripheral side of the first rubber sheet 43.
Furthermore, the driving assembly 6 further comprises a plurality of multi-stage hydraulic cylinders 62, the multi-stage hydraulic cylinders 62 are located above the mounting cover 11 and around the connecting rod 61, the connecting rod 61 penetrates through the middle of the mounting cover 11, a connecting plate 63 is arranged at the top of the multi-stage hydraulic cylinders 62, a spring 64 is arranged at the bottom of the connecting plate 63, a linkage plate 65 is arranged at the bottom of the spring 64, the linkage plate 65 is connected with the connecting rod 61, the multi-stage hydraulic cylinders 62 are used for driving the connecting plate 63 to move in stages, the connecting plate 63 drives the linkage plate 65 to move through the spring 64, so that the connecting rod 61 can move up and down, and due to the staged successive expansion and contraction of the multi-stage hydraulic cylinders 62, the connecting rod 61 cannot drive the moving part 4 and the movable filter assembly 5 to move at one time, and the internal pressure intensity of the multi-stage hydraulic cylinders is not too high when the injector principle is formed between the two parts, the pressure intensity in the filter vat 1 is detected in real time by the pressure detection sensor 45 arranged outside the filter vat 1, and the adsorption capacity of the diatomite between the movable filter component 5 and the movable part 4 is judged by the pressure change degree detected by the pressure detection sensor 45 in the same step, so that the diatomite can be replaced in time.
Further, the middle of the stirring paddle 7 is provided with a connecting ring 72, the connecting ring 72 is sleeved outside the connecting rod 61, the clamping piece 71 is located between the connecting ring 72 and the connecting rod 61, the inner side of the top of the connecting ring 72 is provided with a wedge-shaped tooth groove 73, the wedge-shaped tooth groove 73 is matched with the clamping piece 71, the stirring paddle 7 is matched with the connecting rod 61 through the connecting ring 72, and when the wedge-shaped tooth groove 73 on the connecting ring 72 is clamped with the clamping piece 71, the stirring paddle 7 cannot rotate.
Further, the clamping piece 71 comprises a plurality of wedge-shaped teeth 74, the wedge-shaped teeth 74 are matched with the wedge-shaped tooth sockets 73, a fixing rod 75 is arranged at the bottom of each wedge-shaped tooth 74, a fixing plate 76 is arranged at the bottom of each fixing rod 75, the fixing plate 76 is fixedly connected with the connecting rod 61, a wedge-shaped convex ring 77 is arranged on the outer side of the joint of the fixing plate 76 and the connecting rod 61, so that the stirring paddle 7 can rotate at the position of the wedge-shaped convex ring 77, when the connecting rod 61 moves downwards by using the wedge-shaped teeth 74 in the clamping piece 71, the filter assembly 5 is moved to form sealing with the filter barrel 1, enzymolysis stock solution is pumped in, the stirring paddle 7 is impacted when the enzymolysis stock solution falls down, the stirring paddle 7 falls down, the wedge-shaped teeth 74 are separated from the wedge-shaped tooth sockets 73, and the stirring paddle 7 also has thrust on the enzymolysis stock solution when the stirring paddle 7 impacts on the stirring paddle 7, so that the enzymolysis stock solution is mixed with diatomite, wherein the fixed plate 76 is closely attached to the limit bump 612 above the movable filter component 5, so that the stirring paddle 7 brings up the diatomite above the movable filter component 5 to mix with the enzymolysis stock solution when the stirring paddle rotates under the impact force;
wherein, stirring rake 7 and go-between 72 use the density that material density is less than the enzymolysis stoste, can float in the enzymolysis stoste, make stirring rake 7 and go-between 72 when not receiving external force, go-between 72 come-up, wedge tooth 74 and the merging of wedge tooth socket 73, and then make stirring rake 7 unable rotation, when connecting rod 61 rebound (the enzymolysis stoste filters downwards through removing diatomaceous earth filter 51), diatomaceous earth sediment in the filter vat 1 is in removing diatomaceous earth filter 51 top, the reinforcing removes the filter effect of diatomaceous earth filter 51.
Further, the slag discharging assembly 9 comprises a sealing cover 91, the bottom of the filtering barrel 1 is provided with a slot 92, the sealing cover 91 is arranged to be matched with the slot 92, a sealing plate 93 is arranged at the inner side of the slot 92, the inner diameter of the sealing plate 93 is matched with the inner diameter of the filtering barrel 1, one side of the sealing cover 91 is rotatably connected with one side of the slot 92, a locking piece 94 is arranged at the other side of the sealing cover 91 and the other side of the slot 92, the locking piece 94 is used for locking the sealing cover 91 and the slot 92, the sealing cover 91 is matched with the slot 92, when the degree of pressure change detected by the pressure detection sensor 45 is abnormal, the water pump 3 is stopped to pump water, after the enzymolysis stoste above the removal diatomaceous earth filter 51 is discharged, open sealed cowling 91 through latch fitting 94, change the diatomaceous earth above the removal diatomaceous earth filter 51, perhaps change and remove diatomaceous earth filter 51, guarantee the filter effect of enzymolysis stoste.
When in use, the movable filter component 5 is positioned at the lowest part of the filter barrel 1, the sealing cover 91 is opened to check or replace the movable diatomite filter plate 51 and the fixed diatomite filter plate 8, and then a certain amount of diatomite particles are added above the movable diatomite filter plate 51; then, the operation is started, firstly, the driving component 6 is started, the multistage hydraulic cylinders 62 in the driving component 6 drive the connecting plates 63 to move in a grading manner, the connecting plates 63 drive the linkage plates 65 to move through the springs 64, so that the connecting rods 61 can move up and down, the connecting rods 61 move up first, so that the movable filtering component 5 and the stirring paddles 7 move to the lower side of the movable component 4, the connecting rods 61 stop moving up and move down, then the movable component 4 is driven by the connecting rods 61 to move down and move to the bottommost side of the limiting convex ring 44, and at the moment, the first rubber sheets 43 in the movable component 4 are partially separated from the inner wall of the filtering barrel 1 to form corrugated gaps;
then, the enzymolysis stock solution in the stock solution barrel 2 is pumped into the filter barrel 1 through the water pump 3 and the connecting pipe 12, and the enzymolysis stock solution flows into the upper part of the movable filter component 5 through the through hole 42 on the movable plate 41 and the corrugated gap at the side of the first rubber sheet 43 due to the corrugated gap formed by the first rubber sheet 43, and meanwhile, the connecting rod 61 continuously descends to drive the movable filter component 5 to descend, so that the space above the movable filter component 5 is enlarged; when the movable diatomite filter plate 51 moves downwards, the movable diatomite filter plate 51 pushes the second rubber sheet 52 at the bottom of the movable diatomite filter plate to move downwards, so that the peripheral side of the second rubber sheet 52 is completely matched with the inner wall of the filter barrel 1, the movable piece 4 also moves downwards at the moment, the peripheral side of the first rubber sheet 43 is separated from the inner wall of the filter barrel 1 to form a corrugated gap, an injector principle is formed between the movable filter assembly 5 and the movable piece 4 at the moment, and when the movable filter assembly 5 moves downwards, the zymolysis stock solution above the movable piece 4 is sucked between the movable piece 5 and the movable piece 4 from the corrugated gap formed at the peripheral side of the first rubber sheet 43;
when the movable filter assembly 5 moves to the lowest position, the water pump 3 is stopped to pump the enzymolysis stock solution into the filter vat 1, at this time, the multistage hydraulic cylinder 62 is adjusted to enable the connecting rod 61 to move upwards, and then the connecting rod 61 drives the movable piece 4 to move upwards, the movable plate 41 pushes the first rubber sheet 43 to move upwards at the bottom of the first rubber sheet 43 and moves to the position of the limiting convex ring 44 at the upper side, so that the peripheral side of the first rubber sheet 43 is in complete fit contact with the inner wall of the filter vat 1, and the upper part of the filter vat 1 is tightly plugged; meanwhile, the movable diatomite filter plate 51 in the movable filter assembly 5 is driven by the connecting rod 61, when the movable diatomite filter plate 51 moves upwards, the movable diatomite filter plate 51 drives the second rubber sheet 52 at the bottom of the movable diatomite filter plate 51 to move upwards together, and the peripheral side of the second rubber sheet 52 is separated from the inner wall of the filter barrel 1 due to the friction force between the second rubber sheet 52 and the inner wall of the filter barrel 1 during moving, so that a corrugated gap is formed, the movable member 4 also moves upwards at the moment, a sealing member is formed to seal the top of the filter barrel 1, an injector principle is formed between the movable member 4 and the movable filter assembly 5, and the enzymolysis stock solution between the movable member 4 and the movable filter assembly 5 can be rapidly discharged through the lower part of the movable filter assembly 5.
When the movable filtering component 5 moves downwards, a seal is formed between the movable filtering component 5 and the filtering barrel 1, the enzymolysis stock solution is sucked in, and then the enzymolysis stock solution falls down to impact the stirring paddle 7, so that the stirring paddle 7 falls down, further the wedge-shaped teeth 74 are separated from the wedge-shaped tooth sockets 73, and when the enzymolysis stock solution impacts on the stirring paddle 7, the stirring paddle 7 also has thrust on the enzymolysis stock solution, at the moment, the stirring paddle 7 falls at the lowest part, and can rotate for a short time under the impact of the enzymolysis stock solution, so that the enzymolysis stock solution is mixed with diatomite, the fixing plate 76 is tightly attached to the limiting lug 612 above the movable filtering component 5, so that the diatomite above the movable filtering component 5 is taken up to be mixed with the enzymolysis stock solution when the stirring paddle 7 rotates under the impact;
when moving filter assembly 5 upwards and moving, because stirring rake 7 and go-between 72 use the density that material density is less than the enzymolysis stoste, can float in the enzymolysis stoste, make stirring rake 7 and go-between 72 when not receiving external force, go-between 72 come-up, wedge tooth 74 and wedge tooth's socket 73 merge, and then make stirring rake 7 unable rotation, when connecting rod 61 rebound (enzymolysis stoste is through removing diatomaceous earth filter 51 downward filtration), diatomaceous earth sediment in the filter vat 1 is in removing diatomaceous earth filter 51 top, the reinforcing removes the filter effect of diatomaceous earth filter 51.
After this filter works for a long time, when the pressure transform degree that pressure detection sensor 45 detected appears unusually, stop water pump 3 and draw water, after the enzymolysis stoste discharge of removal diatomaceous earth filter 51 top, open sealed cowling 91 through latch fitting 94, change the diatomaceous earth that removes diatomaceous earth filter 51 top, perhaps change and remove diatomaceous earth filter 51, guarantee the filter effect of enzymolysis stoste.
Further, when the movable filtering component 5 moves downwards, the peripheral side of the second rubber sheet 52 is completely matched with the inner wall of the filtering barrel 1, the moving part 4 also moves downwards at the moment, the peripheral side of the first rubber sheet 43 is separated from the inner wall of the filtering barrel 1 to form a corrugated gap, an injector principle is formed between the movable filtering component 5 and the moving part 4 at the moment, and then the pumped enzymolysis stock solution is sucked between the movable filtering component 5 and the moving part 4 to carry out the mixing treatment of the enzymolysis stock solution and the diatomite; when the movable filtering component 5 moves upwards, the peripheral side of the second rubber sheet 52 is separated from the inner wall of the filtering barrel 1, the formed corrugated gap is matched with the movable part 4 to move upwards, and the sealing part is formed to seal the top of the filtering barrel 1, so that an injector principle is formed between the movable part 4 and the movable filtering component 5, and further, the enzymolysis stock solution between the movable filtering component 4 and the movable filtering component 5 can quickly pass through the movable filtering component 5, so that the clarified filtrate is introduced into the bottom of the filtering barrel 1.
Further, drive connecting plate 63 through multistage pneumatic cylinder 62 in grades and remove, connecting plate 63 drives linkage plate 65 through spring 64 and removes, make connecting rod 61 can reciprocate, and because multistage pneumatic cylinder 62's grading is flexible one by one, make flexible one-level at every turn, rethread spring 64, make connecting rod 61 can once not drive moving part 4 and remove filter assembly 5 and move by a wide margin, and then when having guaranteed its syringe principle of formation between the two, its inside pressure can not be too big, the pressure detection sensor who recycles the setting of filter vat 1 outside carries out real-time detection to the pressure in the filter vat 1, through the pressure transform degree that pressure detection sensor 45 detected between same step, judge the diatomaceous earth adsorption capacity between removal filter assembly 5 and the moving part 4, can in time change diatomaceous earth.
Further, through the wedge-shaped teeth 74 in the clamping piece 71, when the connecting rod 61 drives the movable filtering component 5 to move downwards, a seal is formed between the movable filtering component 5 and the filtering barrel 1, the enzymolysis stock solution is pumped in, and then the stirring paddle 7 is impacted when the enzymolysis stock solution falls down, so that the stirring paddle 7 falls down, and further the wedge-shaped teeth 74 are separated from the wedge-shaped tooth grooves 73, and when the enzymolysis stock solution impacts on the stirring paddle 7, the stirring paddle 7 also has thrust on the enzymolysis stock solution, so that the enzymolysis stock solution is mixed with the diatomite, the fixing plate 76 is tightly attached to the limiting bump 612 above the movable filtering component 5, so that the diatomite above the movable filtering component 5 is brought up to be mixed with the enzymolysis stock solution when the stirring paddle 7 rotates under the impact force; when moving filter assembly 5 upwards and moving, stirring rake 7 floats in the enzymolysis stoste, make stirring rake 7 and go-between 72 when not receiving external force, go-between 72 come-up, wedge tooth 74 and the merging of wedge tooth's socket 73, and then make stirring rake 7 unable rotation, when connecting rod 61 rebound (the enzymolysis stoste is through moving diatomaceous earth filter filtration down), diatomaceous earth sediment in the filter vat is in the removal diatomaceous earth filter 51 top, reinforcing removes the filter effect of diatomaceous earth filter 51.
Further, through sealed cowling 91 cooperation fluting 92, when pressure transform degree that pressure detection sensor 45 detected appears unusual, stop water pump 3 and draw water, after the enzymolysis stoste discharge of removal diatomaceous earth filter 51 top, open sealed cowling 91 through latch fitting 94, conveniently change the diatomaceous earth that removes diatomaceous earth filter 51 top, perhaps change and remove diatomaceous earth filter 51, guarantee the filter effect of enzymolysis stoste.
Furthermore, the enzymolysis stock solution is guided into the space between the movable part 4 and the movable filtering component 5 by the movable part 4 matching with the movable filtering component 5, the diatomite is fully mixed with the enzymolysis stock solution under the action of the stirring paddle 7, the particles in the enzymolysis stock solution are adsorbed, the diatomite is deposited above the movable diatomite filtering plate 51, the enzymolysis stock solution is primarily filtered, the primarily filtered enzymolysis stock solution is secondarily filtered by the fixed diatomite filtering plate 51 at the bottom of the filtering barrel 1, the filtering effect of the filtering machine is further enhanced, meanwhile, the particles in the enzymolysis stock solution are firstly adsorbed by the addition of the diatomite, and when the diatomite filtering plate 51 is used for filtering, only a very small part of the diatomite filtering plate is needed to be filtered, the service life of the diatomite filtering plate 51 is prolonged, and the diatomite is added and mixed with the enzymolysis stock solution, so that the amount of the diatomite is far greater than the content of the diatomite on the diatomite filtering plate 51, and then can use for a long time and just need change, save the time of changing the filter plate when the enzymolysis stoste filters.
Test example 1
The oral administration effect test was performed on the health albumin pearl calcium oral liquids with immunoregulation function prepared in examples 3-6 and comparative examples 1-4.
The test method comprises the following steps: selecting people with weak constitution (all having symptoms of inappetence, pale complexion, leg and foot weakness, insomnia, dreaminess, palpitation, shortness of breath, easy sweating and the like) of 35-55 years old (240 men and women, respectively), randomly dividing men and women into 8 groups of 30 people each, randomly combining 1 group of men and 1 group of women to form a test group of 60 people each, taking the products prepared in examples 3-6 and comparative examples 1-4 respectively, using the notation of the product of example 3 as test group 1, the notation of the product of example 4 as test group 2, the notation of the product of example 5 as test group 3, the notation of the product of example 6 as test group 4, the notation of the product of comparative example 1 as test group 5, the notation of the product of comparative example 2 as test group 6, and the notation of the product of comparative example 3 as test group 7, the product of comparative example 2, designated test group 8, was administered once a day, 20mL each time, for 10 consecutive weeks.
Recording and analyzing the change condition of the constitution, and dividing the evaluation criteria into: (1) the method is remarkably effective: easy falling asleep, obviously reduced times of getting up at night, enhanced appetite, ruddy complexion, powerful legs and feet and good spirit; (2) the method has the following advantages: the sleep is fast, the times of getting up at night are reduced, the appetite is improved, the body feels forceful gradually, and the complexion is improved; (3) and (4) invalidation: no significant change, recorded every 2 weeks.
The analytical results are shown in table 1:
TABLE 1
As can be seen from table 1, the health albumin pearl calcium oral liquid with immunoregulation function, prepared by the invention, contains a large amount of bioactive peptides, soluble calcium, trace elements, abundant small molecular polypeptides and amino acids, can meet energy required by a body, promotes protein synthesis, can quickly and significantly improve the physical condition of people with weak constitution, has health care effect not limited to single sex, and has a considerable effect on males and females. It also has health promoting effect for people with hypoimmunity and postoperative recovery.
In the comparative example 1, the enzymolysis ovalbumin solution is not added, because more than 90% of the components in the pearl are inorganic substances such as calcium carbonate and the like, and the enzymolysis pearl calcium solution contains more amino acids and the like, but the content is relatively less, the content of bioactive peptides such as antioxidant peptide and the like in the prepared oral liquid product is greatly reduced compared with that in the example 3, the protein and enzyme synthesis and regulation capability of a human body is promoted to be weakened, and further, the effects of improving metabolism, enhancing immunity of the human body and the like are reduced, so the body improvement effect of the weak body in the test group 5 is obviously reduced.
In comparative example 2, the enzymatic hydrolyzed pearl calcium solution is not added, and compared with the oral liquid product prepared in example 3, the oral liquid product is not only lack of the effects of soluble calcium and trace elements in the enzymatic hydrolyzed pearl calcium solution, but also lack of amino acids necessary for human bodies to synthesize substances such as immunoglobulin, enzyme, hormone, antibody and the like of human bodies, cannot form a synergistic effect with the enzymatic hydrolyzed ovalbumin solution, and the product effect is remarkably reduced.
In the comparative example 3, compared with the example 4, the quality ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is improved, and the efficacy of the product is obviously reduced; in comparative example 4, compared with example 3, the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid is reduced, and the efficacy of the product is remarkably reduced, which indicates that in the invention, the mass ratio of the enzymolysis ovalbumin liquid to the enzymolysis pearl calcium liquid needs to be kept in a certain range, and the two effective components can exert a synergistic effect, thereby increasing the nutrition of a human body and enhancing and regulating the immune function of the human body.
Test example two
The health albumin pearl calcium oral liquid with immunoregulation function prepared in example 3 and comparative example 5 is subjected to taste and shelf life tests.
(1) And (3) testing the mouthfeel: 20 volunteers were selected, each taking the product of example 3 and comparative example 5 and given a score, on 6 scoring scales: 0 point, 1 point, 2 points, 3 points, 4 points and 5 points, wherein the taste is the worst in the 0 point and the best in the 5 point;
(2) shelf life test: taking 10 clean beakers, respectively pouring the products of the example 3 and the comparative example 5 into 5 beakers, respectively marking the beakers containing the products of the example 3 as 1-1, 1-2, 1-3, 1-4 and 1-5, respectively marking the beakers containing the products of the comparative example 5 as 2-1, 2-2, 2-3, 2-4 and 2-5, respectively pouring 50mL of the beakers into each beaker, placing the beakers in the same room temperature environment in an open mode, and recording the time of decay;
the test results are shown in table 2:
TABLE 2
As can be seen from Table 2, the health albumin pearl calcium oral liquid with immunoregulation function prepared by the invention has good taste, is popular with users, has good antiseptic and antibacterial effects, and can prolong the shelf life of the product, and in comparative example 5, lactic acid is not added, so that the taste is reduced, and the shelf life is obviously shortened.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. A health albumin pearl calcium oral liquid with an immunoregulation function is characterized by comprising the following components in parts by weight:
300 parts of enzymolysis ovalbumin liquid;
50-200 parts of enzymolysis pearl calcium liquid;
50-80 parts of a sweetening agent;
30-50 parts of sour agent.
2. The albumin-pearl calcium oral liquid with immunoregulation function according to claim 1, wherein the sweetener comprises aspartame and stevioside.
3. The albumin-pearl calcium oral liquid with immunoregulatory function according to claim 1, wherein the sour agent comprises lactic acid.
4. A preparation method of a health albumin pearl calcium oral liquid with an immunoregulation function is characterized by comprising the following components in parts by weight:
300 parts of enzymolysis ovalbumin liquid;
50-200 parts of enzymolysis pearl calcium liquid;
50-80 parts of a sweetening agent;
30-50 parts of a sour agent;
the preparation method comprises the following preparation steps:
s1, preparing an enzymolysis ovalbumin solution;
s2, preparing an enzymolysis pearl calcium solution;
and S3, mixing the enzymatic hydrolysis egg white protein liquid, the enzymatic hydrolysis pearl calcium liquid, the sweetening agent and the sour agent in parts by weight, and dissolving and uniformly dispersing to obtain the health albumin pearl calcium oral liquid with the immunoregulation function.
5. The preparation method of the health albumin pearl calcium oral liquid with immunoregulation function as claimed in claim 4, wherein the preparation of the enzymatic ovalbumin liquid comprises the following steps:
(1) adding the egg white powder into pure water, heating and stirring for curing;
(2) after the curing is finished and the mixture is cooled, adding neutral protease for the first time, and carrying out enzymolysis reaction by stirring at a constant temperature;
(3) adding neutral protease for the second time, and performing enzymolysis reaction by stirring at a constant temperature;
(4) after enzymolysis, heating to raise the temperature for enzyme deactivation;
(5) after enzyme deactivation is completed and cooling is performed, obtaining an enzymolysis stock solution A;
(6) mixing the enzymolysis stock solution A with diatomite, soaking, and filtering to obtain clear enzymolysis solution B;
(7) and (4) concentrating the enzymolysis liquid B under reduced pressure to obtain enzymolysis ovalbumin liquid.
6. The preparation method of the health albumin pearl calcium oral liquid with immunoregulation function as claimed in claim 4, wherein the preparation of the enzymatic hydrolysis pearl calcium liquid comprises the following steps:
(1) heat treating Margarita, and naturally cooling;
(2) pulverizing heat-treated Margarita into Margarita calcium powder;
(3) adding pearl calcium powder into pure water, adding lactic acid in several times, and stirring;
(4) heating and stirring to dissolve pearl calcium powder;
(5) after cooling, adding a calcium hydroxide solution to adjust the pH value of the feed liquid to obtain acidolysis solution after acidolysis;
(6) adding neutral protease into the acidolysis solution, and carrying out enzymolysis reaction by stirring at a constant temperature;
(7) after enzymolysis, heating to raise the temperature for enzyme deactivation;
(8) after enzyme deactivation is completed and cooling is performed, obtaining enzymolysis stock solution C;
(9) mixing the enzymolysis stock solution C with diatomite, soaking, and filtering to obtain clear enzymolysis solution D;
(10) and (4) carrying out reduced pressure concentration on the enzymolysis liquid D to obtain enzymolysis pearl calcium liquid.
7. The preparation method of the health albumin pearl calcium oral liquid with the immunoregulation function according to any one of claims 5 to 6, characterized in that a diatomite filter is adopted to filter each enzymolysis stock solution, the diatomite filter comprises a filter vat (1), a stock solution vat (2) is arranged on one side of the filter vat (1), the filter vat (1) is connected with the stock solution vat (2) through a water pump (3), a movable member (4) is arranged above an inner cavity of the filter vat (1), and the sealing degree of the top of the filter vat (1) is changed when the movable member (4) moves up and down;
the middle part of the filter barrel (1) is provided with a movable filter component (5), and the movable filter component (5) comprises a movable diatomite filter plate (51) for primarily filtering enzymolysis stock solution;
the top of the filter barrel (1) is provided with a driving assembly (6), the driving assembly (6) comprises a connecting rod (61), and the driving assembly (6) is connected with the movable filter assembly (5) through the connecting rod (61);
a stirring paddle (7) is arranged at the bottom of the connecting rod (61) above the movable filtering component (5);
the bottom of the filter barrel (1) is provided with a fixed diatomite filter plate (8) for carrying out secondary filtration on the enzymolysis stock solution.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1218690A (en) * | 1997-12-05 | 1999-06-09 | 上海众联生化技术开发有限公司 | Polypeptide oral liquor |
| CN1476782A (en) * | 2002-08-20 | 2004-02-25 | 北京京港耀新生物技术开发有限公司 | Preparation process of complete-component pearl product |
| CN105624255A (en) * | 2016-03-30 | 2016-06-01 | 蔡庭守 | Extraction method for entity small molecule peptide of pearls |
| CN106075385A (en) * | 2016-08-17 | 2016-11-09 | 贵州佰世合意股份有限公司 | A kind of polypeptide oral liquor and preparation method thereof |
| CN110477381A (en) * | 2019-09-03 | 2019-11-22 | 广东紫薇星健康产业有限公司 | A kind of albumin amino acid Calcium oral liquid prescription and preparation method with immunological regulation healthcare function |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1218690A (en) * | 1997-12-05 | 1999-06-09 | 上海众联生化技术开发有限公司 | Polypeptide oral liquor |
| CN1476782A (en) * | 2002-08-20 | 2004-02-25 | 北京京港耀新生物技术开发有限公司 | Preparation process of complete-component pearl product |
| CN105624255A (en) * | 2016-03-30 | 2016-06-01 | 蔡庭守 | Extraction method for entity small molecule peptide of pearls |
| CN106075385A (en) * | 2016-08-17 | 2016-11-09 | 贵州佰世合意股份有限公司 | A kind of polypeptide oral liquor and preparation method thereof |
| CN110477381A (en) * | 2019-09-03 | 2019-11-22 | 广东紫薇星健康产业有限公司 | A kind of albumin amino acid Calcium oral liquid prescription and preparation method with immunological regulation healthcare function |
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