CN113261675A - Probiotic composition suitable for human immunity - Google Patents
Probiotic composition suitable for human immunity Download PDFInfo
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- CN113261675A CN113261675A CN202110615600.9A CN202110615600A CN113261675A CN 113261675 A CN113261675 A CN 113261675A CN 202110615600 A CN202110615600 A CN 202110615600A CN 113261675 A CN113261675 A CN 113261675A
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- 239000006041 probiotic Substances 0.000 title claims abstract description 67
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 67
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 35
- 239000000203 mixture Substances 0.000 title claims abstract description 28
- 230000036039 immunity Effects 0.000 title claims abstract description 17
- 239000011573 trace mineral Substances 0.000 claims abstract description 23
- 235000013619 trace mineral Nutrition 0.000 claims abstract description 23
- 239000000126 substance Substances 0.000 claims abstract description 18
- UQZIYBXSHAGNOE-USOSMYMVSA-N Stachyose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](CO[C@@H]2[C@@H](O)[C@@H](O)[C@@H](O)[C@H](CO)O2)O1 UQZIYBXSHAGNOE-USOSMYMVSA-N 0.000 claims abstract description 16
- 239000000843 powder Substances 0.000 claims abstract description 16
- UQZIYBXSHAGNOE-XNSRJBNMSA-N stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 claims abstract description 16
- 239000002131 composite material Substances 0.000 claims abstract description 15
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 15
- 235000010755 mineral Nutrition 0.000 claims abstract description 15
- 239000011707 mineral Substances 0.000 claims abstract description 15
- 241000186000 Bifidobacterium Species 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000016623 Fragaria vesca Nutrition 0.000 claims abstract description 12
- 235000011363 Fragaria x ananassa Nutrition 0.000 claims abstract description 12
- 239000000654 additive Substances 0.000 claims abstract description 12
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 11
- 239000003765 sweetening agent Substances 0.000 claims abstract description 11
- 241000193171 Clostridium butyricum Species 0.000 claims abstract description 10
- 240000001046 Lactobacillus acidophilus Species 0.000 claims abstract description 10
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims abstract description 10
- 241000186604 Lactobacillus reuteri Species 0.000 claims abstract description 10
- 241000218588 Lactobacillus rhamnosus Species 0.000 claims abstract description 10
- 241000194020 Streptococcus thermophilus Species 0.000 claims abstract description 10
- 229940039695 lactobacillus acidophilus Drugs 0.000 claims abstract description 10
- 229940001882 lactobacillus reuteri Drugs 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 239000008213 purified water Substances 0.000 claims abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 238000002156 mixing Methods 0.000 claims description 46
- 238000003756 stirring Methods 0.000 claims description 24
- 238000001816 cooling Methods 0.000 claims description 20
- 239000000243 solution Substances 0.000 claims description 13
- 241000220223 Fragaria Species 0.000 claims description 11
- 238000001914 filtration Methods 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 8
- 239000003963 antioxidant agent Substances 0.000 claims description 7
- 230000003078 antioxidant effect Effects 0.000 claims description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
- 239000011259 mixed solution Substances 0.000 claims description 6
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 4
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 4
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 4
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 4
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 4
- 229930195725 Mannitol Natural products 0.000 claims description 4
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims description 4
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 4
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 4
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 4
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 claims description 4
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 4
- 239000011575 calcium Substances 0.000 claims description 4
- 229910052791 calcium Inorganic materials 0.000 claims description 4
- 239000000460 chlorine Substances 0.000 claims description 4
- 229910052801 chlorine Inorganic materials 0.000 claims description 4
- 229910052804 chromium Inorganic materials 0.000 claims description 4
- 239000011651 chromium Substances 0.000 claims description 4
- 229910052802 copper Inorganic materials 0.000 claims description 4
- 239000010949 copper Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 239000011737 fluorine Substances 0.000 claims description 4
- 229910052731 fluorine Inorganic materials 0.000 claims description 4
- 238000004108 freeze drying Methods 0.000 claims description 4
- 229910052740 iodine Inorganic materials 0.000 claims description 4
- 239000011630 iodine Substances 0.000 claims description 4
- 239000000832 lactitol Substances 0.000 claims description 4
- 235000010448 lactitol Nutrition 0.000 claims description 4
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims description 4
- 229960003451 lactitol Drugs 0.000 claims description 4
- 239000011777 magnesium Substances 0.000 claims description 4
- 229910052749 magnesium Inorganic materials 0.000 claims description 4
- 239000000845 maltitol Substances 0.000 claims description 4
- 235000010449 maltitol Nutrition 0.000 claims description 4
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims description 4
- 229940035436 maltitol Drugs 0.000 claims description 4
- 229910052748 manganese Inorganic materials 0.000 claims description 4
- 239000011572 manganese Substances 0.000 claims description 4
- 239000000594 mannitol Substances 0.000 claims description 4
- 235000010355 mannitol Nutrition 0.000 claims description 4
- 229960001855 mannitol Drugs 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 4
- 229910052750 molybdenum Inorganic materials 0.000 claims description 4
- 239000011733 molybdenum Substances 0.000 claims description 4
- 239000011574 phosphorus Substances 0.000 claims description 4
- 229910052698 phosphorus Inorganic materials 0.000 claims description 4
- 239000011591 potassium Substances 0.000 claims description 4
- 229910052700 potassium Inorganic materials 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 4
- 239000011669 selenium Substances 0.000 claims description 4
- 229910052711 selenium Inorganic materials 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000000600 sorbitol Substances 0.000 claims description 4
- 235000010356 sorbitol Nutrition 0.000 claims description 4
- 229960002920 sorbitol Drugs 0.000 claims description 4
- 239000004250 tert-Butylhydroquinone Substances 0.000 claims description 4
- 235000019281 tert-butylhydroquinone Nutrition 0.000 claims description 4
- 239000000811 xylitol Substances 0.000 claims description 4
- 235000010447 xylitol Nutrition 0.000 claims description 4
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 4
- 229960002675 xylitol Drugs 0.000 claims description 4
- 239000011701 zinc Substances 0.000 claims description 4
- 229910052725 zinc Inorganic materials 0.000 claims description 4
- 230000000996 additive effect Effects 0.000 claims description 3
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 claims description 2
- 238000007710 freezing Methods 0.000 claims description 2
- 230000008014 freezing Effects 0.000 claims description 2
- 229910052742 iron Inorganic materials 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 15
- 241000894006 Bacteria Species 0.000 abstract description 14
- 230000036541 health Effects 0.000 abstract description 8
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 7
- 235000019605 sweet taste sensations Nutrition 0.000 abstract description 4
- 240000009088 Fragaria x ananassa Species 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 abstract 1
- 244000005700 microbiome Species 0.000 description 8
- 230000000968 intestinal effect Effects 0.000 description 6
- 230000035755 proliferation Effects 0.000 description 6
- 230000006870 function Effects 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 230000000172 allergic effect Effects 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 208000028774 intestinal disease Diseases 0.000 description 3
- 230000003871 intestinal function Effects 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 230000009967 tasteless effect Effects 0.000 description 3
- MRBKEAMVRSLQPH-UHFFFAOYSA-N 3-tert-butyl-4-hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1 MRBKEAMVRSLQPH-UHFFFAOYSA-N 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000002366 mineral element Substances 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 238000000859 sublimation Methods 0.000 description 2
- 230000008022 sublimation Effects 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 235000015816 nutrient absorption Nutrition 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/34—Sugar alcohols
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/173—Reuteri
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/21—Streptococcus, lactococcus
- A23V2400/249—Thermophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides a probiotic composition suitable for human immunity, and relates to the technical field of health products. The probiotic composition comprises the following raw materials in parts by weight: 30-50 parts of composite probiotics, 5-10 parts of trace mineral substances, 3-5 parts of additives, 4-8 parts of strawberry freeze-dried powder, 15-20 parts of stachyose, 10-20 parts of purified water and 5-10 parts of edible mineral substances, wherein the composite probiotics comprise clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus. Through clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus, the health care function of the probiotics is diversified more by various probiotic bacteria, the protection effect on the intestinal tract of a human body is better, stachyose and a sweetening agent added in the preparation process enable the probiotics to have sweet taste after being brewed, the resistance psychology of children when the probiotics are taken is avoided, and the health care beverage is worthy of being popularized vigorously.
Description
Technical Field
The invention relates to the technical field of health care products, in particular to a probiotic composition suitable for human immunity.
Background
The probiotics is an active microorganism which is beneficial to a host and is formed by changing the flora at a certain part of the host through colonization in a human body, and the function of promoting nutrient absorption and keeping the intestinal tract healthy is realized by regulating the immune function of the host mucous membrane and the system or regulating the flora balance in the intestinal tract, so that a single microorganism which is beneficial to the health or a mixed microorganism with a definite composition is generated.
Although the existing probiotic composition contains probiotic bacteria, the types of the probiotic bacteria are single, the protection effect on the intestinal tract of a human body is poor, the probiotic bacteria on the market are colorless and tasteless microorganisms, and the colorless and tasteless microorganisms are brewed to cause children to have resistance psychology when the probiotic bacteria are taken.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a probiotic composition suitable for human immunity, and solves the problems of single thallus type and colorless and tasteless liquid after brewing of the existing probiotic.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: a probiotic composition suitable for human immunity comprises the following raw materials in parts by weight: 30-50 parts of composite probiotics, 5-10 parts of trace mineral substances, 3-5 parts of additives, 4-8 parts of strawberry freeze-dried powder, 15-20 parts of stachyose, 10-20 parts of purified water and 5-10 parts of edible mineral substances, wherein the composite probiotics comprise clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus.
Preferably, the trace minerals comprise three or more trace elements of iron, copper, fluorine, selenium, zinc, chromium, molybdenum, iodine and manganese.
Preferably, the edible mineral comprises three or more trace elements of calcium, potassium, sodium, chlorine, phosphorus and magnesium.
Preferably, the antioxidant comprises tertbutylhydroquinone or butylhydroxyanisole, and the sweetener comprises two or more of xylitol, sorbitol, mannitol, lactitol and maltitol.
Preferably, the preparation method of the probiotic composition comprises the following steps:
s1. mixing treatment
Sequentially adding composite probiotics, trace mineral substances, edible mineral substances and clean water into a mixing container for mixing treatment, stirring the mixing container at the rotating speed of 150-250 r/min, heating the mixing container at the temperature of 30-50 ℃, stirring for 10-20 min, standing for 10-15 min, sequentially adding additives, strawberry freeze-dried powder and stachyose into the mixing container for secondary mixing, stirring the mixing container at the rotating speed of 100-150 r/min, heating the mixing container at the temperature of 40-60 ℃, and stirring for 5-10 min, so that liquid in the mixing container is mixed into a transparent state;
s2, cooling treatment
Pouring the mixed solution into a sealed container, placing the sealed container in a cooling chamber, cooling the sealed container at the temperature of 3-8 ℃, and cooling for 2-3 hours;
s3, filtering and drying treatment
Filtering the solution by using a screen with the surface mesh size of 40-60 meshes, putting the filtered solution into a freeze dryer, cooling the freeze dryer to-45-minus 60 ℃ for freeze drying treatment, and freezing and sublimating the water in the solution to obtain powdery probiotics;
s4. production treatment
And (3) putting the freeze-dried powder into a stirring tank, stirring and mixing at the rotating speed of 500-700 r/min for 5-8 min, and sealing and subpackaging the mixed powdery probiotics according to the standard of 2 g/bag.
(III) advantageous effects
The invention provides a probiotic composition suitable for human immunity. The method has the following beneficial effects:
1. the invention uses the composite probiotics including clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus, wherein the bifidobacterium has the effect of improving the intestinal function and reducing the side effect of antibiotic treatment, the lactobacillus reuteri can improve the intestinal flora distribution, antagonize the colonization of harmful bacteria, improve the immunity and promote the metabolism, the lactobacillus acidophilus has the effects of adjusting the intestinal flora balance and inhibiting the proliferation of undesirable microorganisms, the streptococcus thermophilus can help lactose digestion, the lactobacillus rhamnosus can adjust the immune balance and relieve the allergic symptoms, the clostridium butyricum can promote the proliferation of the bifidobacterium and inhibit the growth and the reproduction of the harmful bacteria, the stachyose can effectively prevent and relieve the constipation and the diarrhea of infants, inhibit intestinal diseases and enhance the immunocompetence of the infants, the health care function of the probiotic composition is more diversified by the various probiotic bacteria, and the protection effect on the intestinal tract of a human body is better.
2. According to the invention, stachyose and a sweetening agent are added in the preparation process, so that the powdery probiotic composition has slight sweet taste after being brewed, and the strawberry freeze-dried powder enables the probiotics to be red liquid after being brewed, thereby avoiding the resistance psychology of children when the composition is taken.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
the embodiment of the invention provides a probiotic composition suitable for human immunity, which comprises the following raw materials in parts by weight: 30 parts of composite probiotics, 5 parts of trace mineral substances, 3 parts of additives, 4 parts of strawberry freeze-dried powder, 15 parts of stachyose, 10 parts of purified water and 5 parts of edible mineral substances, wherein the composite probiotics comprise clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus, the bifidobacterium has the effect of improving the intestinal function and reducing the side effect of antibiotic treatment, the lactobacillus reuteri can improve the intestinal flora distribution, antagonize the permanent planting of harmful bacteria, improve the immunity and promote the metabolism, the lactobacillus acidophilus has the effect of adjusting the intestinal flora balance and inhibiting the proliferation of undesirable microorganisms, the streptococcus thermophilus can help the lactose digestion, the lactobacillus rhamnosus can adjust the immune balance and relieve the allergic symptoms, the clostridium butyricum can promote the proliferation of the bifidobacterium and inhibit the growth and the propagation of the harmful bacteria, the health care function of the probiotic composition is more diversified by the various probiotic bacteria, and the protection effect on the intestinal tract of a human body is better.
The trace mineral comprises three or more trace elements of ferrum, copper, fluorine, selenium, zinc, chromium, molybdenum, iodine and manganese.
The edible mineral comprises three or more trace elements of calcium, potassium, sodium, chlorine, phosphorus and magnesium, and the trace mineral and the edible mineral are added in the preparation process to supplement mineral elements required by the body of the infant every day.
The additive comprises antioxidant and sweetener, the antioxidant comprises tert-butylhydroquinone or butyl hydroxy anisol, and the sweetener comprises two or more of xylitol, sorbitol, mannitol, lactitol, and maltitol.
A method of preparing a probiotic composition, comprising the steps of:
s1. mixing treatment
Sequentially adding composite probiotics, trace mineral substances, edible mineral substances and clean water into a mixing container for mixing treatment, stirring the mixing container at the rotating speed of 150r/min, heating the mixing container at the temperature of 30 ℃, stirring for 10min, standing for 10min, sequentially adding additives, strawberry freeze-dried powder and stachyose into the mixing container for secondary mixing, stirring the mixing container at the rotating speed of 100r/min, heating the mixing container at the temperature of 40 ℃, stirring for 5min, mixing liquid in the mixing container into a transparent state, wherein the stachyose can effectively prevent and relieve constipation and diarrhea of infants, inhibit intestinal diseases and enhance the immunocompetence of the infants, and the powdery probiotic composition has slight sweet taste after being brewed by the stachyose and a sweetening agent added in the preparation process, the strawberry freeze-dried powder makes probiotics appear as red liquid after being brewed, so that the resistance psychology of children is avoided when the probiotics are taken;
s2, cooling treatment
Pouring the mixed solution into a sealed container, cooling the mixed solution in a cooling chamber at the temperature of 3 ℃, and cooling for 2 hours;
s3, filtering and drying treatment
Filtering the solution by using a screen with the surface mesh size of 40 meshes, putting the filtered solution into a freeze dryer, cooling the freeze dryer to-45 ℃ for freeze drying treatment, and carrying out freeze sublimation on water in the solution to obtain powdery probiotics;
s4. production treatment
And (3) putting the freeze-dried powder into a stirring tank, stirring and mixing at the rotating speed of 500r/min for 5min, and sealing and subpackaging the mixed powdery probiotics according to the standard of 2 g/bag.
Example two:
the embodiment of the invention provides a probiotic composition suitable for human immunity, which comprises the following raw materials in parts by weight: 50 parts of composite probiotics, 10 parts of trace mineral substances, 5 parts of additives, 8 parts of strawberry freeze-dried powder, 20 parts of stachyose, 20 parts of purified water and 10 parts of edible mineral substances, wherein the composite probiotics comprise clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus, the bifidobacterium has the effect of improving the intestinal function and reducing the side effect of antibiotic treatment, the lactobacillus reuteri can improve the distribution of intestinal flora and antagonize the permanent planting of harmful bacteria, the immunity is improved, and the metabolism is promoted, the lactobacillus acidophilus has the effect of adjusting the balance of the intestinal flora and inhibiting the proliferation of undesirable microorganisms, the streptococcus thermophilus can help the lactose digestion, the lactobacillus rhamnosus can adjust the immune balance and relieve the allergic symptoms, the clostridium butyricum can promote the proliferation of the bifidobacterium and inhibit the growth and the propagation of the harmful bacteria, the health care function of the probiotic composition is more diversified by the various probiotic bacteria, and the protection effect on the intestinal tract of a human body is better.
The trace mineral comprises three or more trace elements of ferrum, copper, fluorine, selenium, zinc, chromium, molybdenum, iodine and manganese.
The edible mineral comprises three or more trace elements of calcium, potassium, sodium, chlorine, phosphorus and magnesium, and the trace mineral and the edible mineral are added in the preparation process to supplement mineral elements required by the body of the infant every day.
The additive comprises antioxidant and sweetener, the antioxidant comprises tert-butylhydroquinone or butyl hydroxy anisol, and the sweetener comprises two or more of xylitol, sorbitol, mannitol, lactitol, and maltitol.
A method of preparing a probiotic composition, comprising the steps of:
s1. mixing treatment
Sequentially adding composite probiotics, trace mineral substances, edible mineral substances and clean water into a mixing container for mixing treatment, stirring the mixing container at the rotating speed of 250r/min, heating the mixing container at the temperature of 50 ℃, stirring for 20min, standing for 15min, sequentially adding additives, strawberry freeze-dried powder and stachyose into the mixing container for secondary mixing, stirring the mixing container at the rotating speed of 150r/min, heating the mixing container at the temperature of 60 ℃, stirring for 10min, mixing liquid in the mixing container into a transparent state, wherein the stachyose can effectively prevent and relieve constipation and diarrhea of infants, inhibit intestinal diseases and enhance the immunocompetence of the infants, and the powdery probiotic composition has slight sweet taste after being brewed by the stachyose and a sweetening agent added in the preparation process, the strawberry freeze-dried powder makes probiotics appear as red liquid after being brewed, so that the resistance psychology of children is avoided when the probiotics are taken;
s2, cooling treatment
Pouring the mixed solution into a sealed container, cooling the mixed solution in a cooling chamber at the temperature of 8 ℃, and cooling for 3 hours;
s3, filtering and drying treatment
Filtering the solution by using a screen with the surface mesh size of 60 meshes, putting the filtered solution into a freeze dryer, cooling the freeze dryer to-60 ℃ for freeze drying treatment, and carrying out freeze sublimation on water in the solution to obtain powdery probiotics;
s4. production treatment
And (3) putting the freeze-dried powder into a stirring tank, stirring and mixing at the rotating speed of 700r/min for 8min, and sealing and subpackaging the mixed powdery probiotics according to the standard of 2 g/bag.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. A probiotic composition suitable for human immunity is characterized in that: the feed comprises the following raw materials in parts by weight: 30-50 parts of composite probiotics, 5-10 parts of trace mineral substances, 3-5 parts of additives, 4-8 parts of strawberry freeze-dried powder, 15-20 parts of stachyose, 10-20 parts of purified water and 5-10 parts of edible mineral substances, wherein the composite probiotics comprise clostridium butyricum, bifidobacterium, lactobacillus reuteri, lactobacillus acidophilus, streptococcus thermophilus and lactobacillus rhamnosus.
2. The probiotic composition suitable for human immunity according to claim 1, wherein: the trace mineral comprises three or more trace elements of iron, copper, fluorine, selenium, zinc, chromium, molybdenum, iodine and manganese.
3. The probiotic composition suitable for human immunity according to claim 1, wherein: the edible mineral comprises three or more trace elements of calcium, potassium, sodium, chlorine, phosphorus and magnesium.
4. The probiotic composition suitable for human immunity according to claim 1, wherein: the additive comprises an antioxidant and a sweetener, wherein the antioxidant comprises tert-butylhydroquinone or butyl hydroxy anisole, and the sweetener comprises two or more of xylitol, sorbitol, mannitol, lactitol and maltitol.
5. The probiotic composition suitable for human immunity according to claim 1, wherein: the preparation method of the probiotic composition comprises the following steps:
s1. mixing treatment
Sequentially adding composite probiotics, trace mineral substances, edible mineral substances and clean water into a mixing container for mixing treatment, stirring the mixing container at the rotating speed of 150-250 r/min, heating the mixing container at the temperature of 30-50 ℃, stirring for 10-20 min, standing for 10-15 min, sequentially adding additives, strawberry freeze-dried powder and stachyose into the mixing container for secondary mixing, stirring the mixing container at the rotating speed of 100-150 r/min, heating the mixing container at the temperature of 40-60 ℃, and stirring for 5-10 min, so that liquid in the mixing container is mixed into a transparent state;
s2, cooling treatment
Pouring the mixed solution into a sealed container, placing the sealed container in a cooling chamber, cooling the sealed container at the temperature of 3-8 ℃, and cooling for 2-3 hours;
s3, filtering and drying treatment
Filtering the solution by using a screen with the surface mesh size of 40-60 meshes, putting the filtered solution into a freeze dryer, cooling the freeze dryer to-45-minus 60 ℃ for freeze drying treatment, and freezing and sublimating the water in the solution to obtain powdery probiotics;
s4. production treatment
And (3) putting the freeze-dried powder into a stirring tank, stirring and mixing at the rotating speed of 500-700 r/min for 5-8 min, and sealing and subpackaging the mixed powdery probiotics according to the standard of 2 g/bag.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114431476A (en) * | 2022-02-28 | 2022-05-06 | 山东拜因诺生物科技有限公司 | Special probiotics for women |
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Application publication date: 20210817 |