CN112691172A - 预防非洲猪瘟的一种新型添加剂发酵中药 - Google Patents
预防非洲猪瘟的一种新型添加剂发酵中药 Download PDFInfo
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- CN112691172A CN112691172A CN201911009984.9A CN201911009984A CN112691172A CN 112691172 A CN112691172 A CN 112691172A CN 201911009984 A CN201911009984 A CN 201911009984A CN 112691172 A CN112691172 A CN 112691172A
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- swine fever
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Abstract
本发明提供了预防非洲猪瘟的一种新型添加剂发酵中药,该添加剂发酵中药由中药化裁辅以八种活菌配置而成,其中中药的具体成分如下:黄芪120g,当归30g,甘草15g,川芎25g,党参60g,白术30g,板蓝根60g。本发明通过在黄芪、当归、甘草等混合发酵的中药材中添加蟾酥抗菌肽芽孢杆菌、双歧杆菌等八种活菌,使得该发酵中药产生了补气、活血化瘀、止痛、改善微循环、清泄肝胆实火、排毒解毒、补中益气、补肾填精、提升特异性和非特异性免疫力、调理胃肠、补充营养、消食健胃、提高饲料转化率、改善环境、降低动物呼吸道发病率的功效,同时八种活菌增效中药效用达30倍左右,使得中药的药效得到充分的发挥,确保了该发酵中药对非洲猪瘟的防治效果。
Description
技术领域
本发明属于预防非洲猪瘟的中药技术领域,尤其是涉及预防非洲猪瘟的一种新型添加剂发酵中药。
背景技术
非洲猪瘟是一种急性、发热传染性很高的滤过性病毒所引起的猪病,其特征是发病过程短,但死亡率高达100%,病猪临床表现为发热,皮肤发绀,***,肾,胃肠粘膜明显出血。
在生猪养殖的过程中,养殖户会不可避免的遇到非洲猪瘟的问题,为了能够避免非洲猪瘟对生猪的影响,确保养殖户的收益,本发明提出了预防非洲猪瘟的一种新型添加剂发酵中药,克服了传统的发酵中药药效低、中药药效得不到充分发挥、对非洲猪瘟的防治效果差的弊端。
发明内容
有鉴于此,本发明旨在提出预防非洲猪瘟的一种新型添加剂发酵中药,能够有效增强机体免疫力,提高机体的消化吸收效率,预防非洲猪瘟的发生。
为达到上述目的,本发明的技术方案是这样实现的:
预防非洲猪瘟的一种新型添加剂发酵中药,该添加剂发酵中药由中药化裁辅以八种活菌配置而成,其中中药的具体成分如下:黄芪120g,当归30g,甘草15g,川芎25g,党参60g,白术30g,板蓝根60g,淫羊藿30g,龙胆45g,黄连35g,何首乌25g,白头翁45g,陈皮25g,麦芽120g,神曲60克g,山楂60g,艾叶30g,绵马贯众20。
进一步的,所述的八种活菌分别为枯草芽孢杆菌、蟾酥抗菌肽芽孢杆菌、植物乳酸菌、嗜酸乳杆菌、双歧杆菌、丁酸梭菌、地衣芽孢杆菌、酵母菌,活菌蟾酥抗菌肽芽孢杆菌的添加,能有效抑制癌细胞及肿瘤的生长,对多重耐药菌和肿瘤细胞有较强的灭活作用,而不会破坏动物机体的正常细胞,是一类具有巨大发展潜力的新型抗菌肽,也是目前抗病原微生物开发的一个热点,双歧杆菌的添加也解决了本品的抗菌抗病毒的效果,而枯草芽孢杆菌、地衣芽孢杆菌、嗜酸乳杆菌、丁酸梭菌等的参与,可促进包括B细胞、T细胞、M细胞、吞噬细胞、体液免疫、细胞免疫、产溶菌酶细胞在内的免疫细胞的活性,产生多种消化酶,促进对蛋白质、脂类、碳水化合物、维生素、无机盐和黏液代谢等营养的消化、吸收和代谢,并能使胃肠菌群产生迁移传动复合物,刺激肠蠕动,而且还能代谢产酸,酸化肠道环境,活化酶***和抑制偏碱性有害微生物的生长。动物的微生态***就是通过上述多种作用,最终产生抑制有害菌群,增强免疫功能,防治疾病,提高饲料营养素的消化吸收和转化效率,促进动物产品的形成和品质改善。
进一步的,所述的八种活菌的含量均大于等于2.0X107Cfu/g,通过上述八种活菌的共同作用,使得该发酵中药产生了补气、活血化瘀、止痛、改善微循环、清泄肝胆实火、排毒解毒、补中益气、补肾填精、提升特异性和非特异性免疫力、调理胃肠、补充营养、消食健胃、提高饲料转化率、改善环境、降低动物呼吸道发病率的功效,同时八种活菌增效中药效用达30倍左右,使得中药的药效得到充分的发挥,确保了该发酵中药对非洲猪瘟的防治效果。
所述的添加剂发酵中药的制备方法,包括如下步骤:
(1)取上述重量份的黄芪、当归、甘草、川芎、党参等中药材,进行混合粉碎,并进行熬制浓缩处理,以制得浓缩液备用;
(2)将上述八种活菌以及步骤(1)所制得的浓缩液混到一起,进行发酵;
(3)发酵一段时间后,只需将发酵好的物料进行密封装袋,即可投入使用。
进一步的,所述的步骤(2)中的发酵温度为42℃,所述步骤(2)中的发酵时间为20ds。
进一步的,该发酵中药的实用方法如下:母猪在非洲猪瘟瘟期间按4%添加一月即可抵抗该病的影响,由于母猪体内毒素承载量大,所以周期30天左右,只要用到时用够量即可,保育猪、中大猪可按4%~6%添加三周以上也是可以的。
相对于现有技术,本发明所述的添加剂发酵中药具有以下优势:
本发明通过在黄芪、当归、甘草等混合发酵的中药材中添加蟾酥抗菌肽芽孢杆菌、双歧杆菌等八种活菌,使得该发酵中药产生了补气、活血化瘀、止痛、改善微循环、清泄肝胆实火、排毒解毒、补中益气、补肾填精、提升特异性和非特异性免疫力、调理胃肠、补充营养、消食健胃、提高饲料转化率、改善环境、降低动物呼吸道发病率的功效,同时八种活菌增效中药效用达30倍左右,使得中药的药效得到充分的发挥,确保了该发酵中药对非洲猪瘟的防治效果。
具体实施方式
发酵中药是将天然药物(中药)提取液以优选的肠道益生菌菌群中一种或几种、一株或几株益生菌作为菌种,利用微生态学、仿生学的方法,通过生物嫁接的方式,在体外模拟机体的肠道环境和中药成分在机体内的消化分解过程,对提取的中药有效成分进行生物学转化,将中药的大分子物质,经过微生物转化成为能够被机体肠道直接吸收的小分子成分,使中药成为快速吸收、定量疗效的新型药物。
基于上述作用机理,本发明提供了预防非洲猪瘟的一种新型添加剂发酵中药,该添加剂发酵中药由中药化裁辅以八种活菌配置而成,其中中药的具体成分如下:黄芪120g,当归30g,甘草15g,川芎25g,党参60g,白术30g,板蓝根60g,淫羊藿30g,龙胆45g,黄连35g,何首乌25g,白头翁45g,陈皮25g,麦芽120g,神曲60克g,山楂60g,艾叶30g,绵马贯众20。
优选的,所述的八种活菌分别为枯草芽孢杆菌、蟾酥抗菌肽芽孢杆菌、植物乳酸菌、嗜酸乳杆菌、双歧杆菌、丁酸梭菌、地衣芽孢杆菌、酵母菌,活菌蟾酥抗菌肽芽孢杆菌的添加,能有效抑制癌细胞及肿瘤的生长,对多重耐药菌和肿瘤细胞有较强的灭活作用,而不会破坏动物机体的正常细胞,是一类具有巨大发展潜力的新型抗菌肽,也是目前抗病原微生物开发的一个热点,双歧杆菌的添加也解决了本品的抗菌抗病毒的效果,而枯草芽孢杆菌、地衣芽孢杆菌、嗜酸乳杆菌、丁酸梭菌等的参与,可促进包括B细胞、T细胞、M细胞、吞噬细胞、体液免疫、细胞免疫、产溶菌酶细胞在内的免疫细胞的活性,产生多种消化酶,促进对蛋白质、脂类、碳水化合物、维生素、无机盐和黏液代谢等营养的消化、吸收和代谢,并能使胃肠菌群产生迁移传动复合物,刺激肠蠕动,而且还能代谢产酸,酸化肠道环境,活化酶***和抑制偏碱性有害微生物的生长。动物的微生态***就是通过上述多种作用,最终产生抑制有害菌群,增强免疫功能,防治疾病,提高饲料营养素的消化吸收和转化效率,促进动物产品的形成和品质改善。
优选的,所述的八种活菌的含量均大于等于2.0X107Cfu/g,通过上述八种活菌的共同作用,使得该发酵中药产生了补气、活血化瘀、止痛、改善微循环、清泄肝胆实火、排毒解毒、补中益气、补肾填精、提升特异性和非特异性免疫力、调理胃肠、补充营养、消食健胃、提高饲料转化率、改善环境、降低动物呼吸道发病率的功效,同时八种活菌增效中药效用达30倍左右,使得中药的药效得到充分的发挥,确保了该发酵中药对非洲猪瘟的防治效果。
所述的添加剂发酵中药的制备方法,包括如下步骤:
(1)取上述重量份的黄芪、当归、甘草、川芎、党参等中药材,进行混合粉碎,并进行熬制浓缩处理,以制得浓缩液备用;
(2)将上述八种活菌以及步骤(1)所制得的浓缩液混到一起,进行发酵;
(3)发酵一段时间后,只需将发酵好的物料进行密封装袋,即可投入使用。
优选的,所述的步骤(2)中的发酵温度为42℃,所述步骤(2)中的发酵时间为20ds。
优选的,该发酵中药的实用方法如下:母猪在非洲猪瘟瘟期间按4%添加一月即可抵抗该病的影响,由于母猪体内毒素承载量大,所以周期30天左右,只要用到时用够量即可,保育猪、中大猪可按4%~6%添加三周以上也是可以的。
以上所述仅为本发明的较佳实施例而已,并不用以限制本发明,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。
Claims (6)
1.预防非洲猪瘟的一种新型添加剂发酵中药,其特征在于:该添加剂发酵中药由中药化裁辅以八种活菌配置而成,其中中药的具体成分如下:黄芪120g,当归30g,甘草15g,川芎25g,党参60g,白术30g,板蓝根60g,淫羊藿30g,龙胆45g,黄连35g,何首乌25g,白头翁45g,陈皮25g,麦芽120g,神曲60克g,山楂60g,艾叶30g,绵马贯众20g。
2.根据权利要求1所述的添加剂发酵中药,其特征在于:所述的八种活菌分别为枯草芽孢杆菌、蟾酥抗菌肽芽孢杆菌、植物乳酸菌、嗜酸乳杆菌、双歧杆菌、丁酸梭菌、地衣芽孢杆菌、酵母菌。
3.根据权利要求1-2所述的添加剂发酵中药,其特征在于:所述的八种活菌的含量均大于等于2.0X107Cfu/g。
4.权利要求1-3中任一项所述的添加剂发酵中药的制备方法,其特征在于:包括如下步骤:
(1)取上述重量份的黄芪、当归、甘草、川芎、党参等中药材,进行混合粉碎,并进行熬制浓缩处理,以制得浓缩液备用;
(2)将上述八种活菌以及步骤(1)所制得的浓缩液混到一起,进行发酵;
(3)发酵一段时间后,只需将发酵好的物料进行密封装袋,即可投入使用。
5.根据权利要求4所述的添加剂发酵中药的制备方法,其特征在于:所述的步骤(2)中的发酵温度为42℃,所述步骤(2)中的发酵时间为20ds。
6.根据权利要求1-5所述的添加剂发酵中药,其特征在于:该发酵中药的使用方法如下:母猪在非洲猪瘟瘟期间按4%添加一月即可抵抗该病的影响,由于母猪体内毒素承载量大,所以周期30天左右,只要用到时用够量即可,保育猪、中大猪可按4%~6%添加三周以上也是可以的。
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CN114766590A (zh) * | 2022-05-14 | 2022-07-22 | 宿州市美联阳光饲料有限责任公司 | 一种中草药型抗病毒饲料 |
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