CN112294681B - Formula of shampoo - Google Patents
Formula of shampoo Download PDFInfo
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- CN112294681B CN112294681B CN202011108942.3A CN202011108942A CN112294681B CN 112294681 B CN112294681 B CN 112294681B CN 202011108942 A CN202011108942 A CN 202011108942A CN 112294681 B CN112294681 B CN 112294681B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a formula of shampoo, which belongs to the technical field of living bath articles, and comprises hair oil, a surfactant, a thickening agent, an anti-dandruff agent, a nutritional agent, a preservative, a conditioning agent, a chelating agent, a pH regulator, a pearling agent and water; wherein the surfactant contains functional agent diosmetin-7-O-glucoside and/or isoerythrocin. The shampoo formula is obtained by adopting diosmetin-7-O-glucoside and/or isoxarin, so that the shampoo formula has the following beneficial effects: the foaming property is good, and the foam height reaches more than 140 mm; the foaming stability is good, and the foam height reduction rate is below 2% after 5 min; the flexibility is good, and the dynamic friction coefficient is below 0.12; the combing property is good, the wet combing force is below 2.3N, and the dry combing force is below 1.5N.
Description
Technical Field
The invention belongs to the technical field of living bath supplies, and particularly relates to a formula of shampoo.
Background
The shampoo is also called shampoo, shampoo or shampoo, is an essential daily product in life, and the requirements of people on the shampoo are higher and higher along with the continuous improvement of the living standard. It not only needs to have good cleaning effect, but also needs to have the characteristics of flexibility, easy carding and the like.
Disclosure of Invention
The invention aims to provide a formula of shampoo with good foamability, good foaming stability, good flexibility and good combing property.
The technical scheme adopted by the invention for realizing the purpose is as follows:
a shampoo, comprising:
the hair moistening oil is emulsified silicone oil; the surfactant comprises a main surfactant, a cosurfactant and a functional agent, wherein the main surfactant comprises sodium laureth sulfate, the cosurfactant comprises one or a mixture of cocamidopropyl betaine, sodium lauroyl sarcosinate and decyl glucoside, and the functional agent is diosmetin-7-O-glucoside and/or isoxarin; thickening agent, dandruff removing agent, nutritional agent, preservative, conditioning agent, chelating agent, pH regulator, pearling agent and water. The sodium laureth sulfate has full, white and fine foam, is easy to dissolve in water and can be quickly biodegraded; one or a mixture of cocamidopropyl betaine, sodium lauroyl sarcosinate and decyl glucoside is selected as the auxiliary surfactant, so that better foaming property, foam stability, proper viscosity and mild degree of the product are provided for the shampoo; diosmetin-7-O-glucoside and/or isoxatilin are added into shampoo, and interact with the main surfactant and the auxiliary surfactant, so that the foamability and foaming stability of the shampoo are further improved, and the flexibility and combing easiness of the shampoo are improved.
The invention discloses application of diosmetin-7-O-glucoside and/or isoxarin, which is at least one of the following 1) to 4):
1) the foaming property of the shampoo is improved;
2) the foaming stability of the shampoo is improved;
3) the flexibility of the shampoo is improved;
4) the combing performance of the shampoo is improved.
More preferably, the hair oil or fat is a high, medium or low viscosity silicone emulsion. Moisten hair and repair the damage of hair scales.
Preferably, the thickener comprises one or a mixture of sodium chloride, cocamide MEA, PEG-150 distearate and PPG-2 hydroxyethyl cocamide. The thickening agent is used for improving the stability of the shampoo formula, improving the viscosity of the shampoo formula and improving the operability during use.
Preferably, the antidandruff agent is climbazole. Has good antibacterial effect on Pityrosporum ovale, Candida albicans and Trichophyton which cause dandruff.
Preferably, the nutritional agent is an oat polypeptide extract. Similar to proteins constituting hair, has good affinity, and can effectively permeate into hair to repair damaged hair.
Preferably, the preservative is cason. Controlling the growth of microorganisms in the shampoo and preventing the microorganisms of the product from exceeding the specified range in the shelf life.
Preferably, the conditioning agent is polyquaternium-10. Neutralizing the charge and eliminating the electrostatic effect of hair.
Preferably, the chelating agent is disodium EDTA. Stabilizing shampoo formula, preventing discoloration and other problems.
Preferably, the pH adjusting agents are citric acid and sodium citrate. The scalp surface is weakly acidic, and the shampoo is adjusted to be weakly acidic.
Preferably, the pearling agent is one or a mixture of Ethylene Glycol Monostearate (EGMS) and Ethylene Glycol Distearate (EGDS). Enhancing the appearance of the shampoo.
Preferably, the shampoo comprises the following components in parts by mass:
2-4 parts of hair-moistening grease, 20-40 parts of surfactant, 0.5-2 parts of thickener, 0.1-1 part of anti-dandruff agent, 0.3-2 parts of nutritional agent, 0.05-0.5 part of preservative, 0.1-0.5 part of conditioner, 0.03-0.1 part of chelating agent, 0.5-5 parts of pH regulator, 1-2 parts of pearling agent and 50-70 parts of water.
More preferably, the shampoo comprises the following components in parts by mass:
2.5 parts of hair-moistening grease, 23 parts of surfactant, 0.9 part of thickening agent, 0.3 part of anti-dandruff agent, 0.8 part of nutritional agent, 0.15 part of preservative, 0.15 part of conditioning agent, 0.05 part of chelating agent, 2 parts of pH regulator, 1.2 parts of pearling agent and 55 parts of water.
More preferably, the shampoo comprises the following components in parts by mass:
3.6 parts of hair-moistening grease, 35 parts of surfactant, 1.8 parts of thickening agent, 0.9 part of anti-dandruff agent, 1.6 parts of nutritional agent, 0.47 part of preservative, 0.43 part of conditioner, 0.09 part of chelating agent, 2 parts of pH regulator, 1.8 parts of pearling agent and 67 parts of water.
Preferably, the addition amount of diosmetin-7-O-glucoside in the surfactant is 1-4wt% of the main surfactant, and the addition amount of isoxarotenone is 0.5-5wt% of the main surfactant.
More preferably, the addition amount of diosmetin-7-O-glucoside in the surfactant is 1.5wt% of the main surfactant, and the addition amount of isoxatilin is 1.5wt% of the main surfactant.
More preferably, the addition amount of diosmetin-7-O-glucoside in the surfactant is 2wt% of the main surfactant, and the addition amount of isoxarotenone is 3.5% of the main surfactant.
More preferably, the conditioner further comprises Z-D-arginine hydrochloride and choline bitartrate. The addition amount of the Z-D-arginine hydrochloride is 1 to 3 percent of the polyquaternium-10 by weight, and the addition amount of the choline bitartrate is 0.6 to 2.4 percent of the polyquaternium-10 by weight. The Z-D-arginine hydrochloride and the choline bitartrate are dissolved in the shampoo and act with each component in the shampoo to further improve the foamability, the foaming stability, the flexibility and the combing easiness of the shampoo, and when the Z-D-arginine hydrochloride or the choline bitartrate is used independently, the foamability and the foaming stability are not influenced basically, and the flexibility and the combing easiness are improved slightly.
The shampoo formula is obtained by adopting diosmetin-7-O-glucoside and/or isoxarin, so that the shampoo formula has the following beneficial effects: the foaming property is good, and the foam height reaches more than 140 mm; the foaming stability is good, and the foam height reduction rate is below 2% after 5 min; the flexibility is good, and the dynamic friction coefficient is below 0.12; the combing property is good, the wet combing force is below 2.3N, and the dry combing force is below 1.5N. The invention further adopts Z-D-arginine hydrochloride and choline bitartrate in the formula, thereby further improving the foaming property, foaming stability, flexibility and combing property of the shampoo. Therefore, the shampoo formula has the advantages of good foamability, good foaming stability, good flexibility and good combing property.
Drawings
FIG. 1 is a graph showing the results of foaming performance of shampoo;
FIG. 2 is a graph showing the results of shampoo foaming stability;
FIG. 3 is a graph showing results of hair strand pliability after shampoo rinsing;
FIG. 4 is a graph showing wet combing results of a hair tress after shampoo rinsing;
FIG. 5 is a graph showing the results of dry combing of hair strands after shampoo rinsing.
Detailed Description
The technical solution of the present invention is further described in detail below with reference to the following detailed description and the accompanying drawings:
example 1:
a formula of a shampoo is provided,
2.5 parts of hair-moistening grease, 23 parts of surfactant, 0.9 part of thickening agent, 0.3 part of anti-dandruff agent, 0.8 part of nutritional agent, 0.15 part of preservative, 0.15 part of conditioning agent, 0.05 part of chelating agent, 2 parts of pH regulator, 1.2 parts of pearling agent and 55 parts of water.
The hair oil is emulsified silicone oil, the emulsified silicone oil comprises large-particle-size emulsified silicone oil (the content of silicone oil is 60 percent, and the internal phase viscosity is 30-100 ten thousand) and small-particle-size emulsified silicone oil (the content of silicone oil is 60 percent, and the internal phase viscosity is 30-100 ten thousand), and the mass ratio of the large-particle-size emulsified silicone oil to the small-particle-size emulsified silicone oil is 1: 2 was used.
The surfactant comprises a main surfactant sodium laureth sulfate (70%), a cosurfactant cocamidopropyl betaine (30%) and a functional agent, wherein the main surfactant and the cosurfactant are mixed in a mass ratio of 4: 1, the functional agent comprises diosmetin-7-O-glucoside and isoxarotenone, the dosage of the diosmetin-7-O-glucoside is 1.5wt% of the main surface active agent, and the dosage of the isoxarotenone is 1.5wt% of the main surface active agent.
The thickening agent is a mixture of cocamide MEA and PEG-150 distearate, wherein the weight ratio of the cocamide MEA to the PEG-150 distearate is 1: 2 in a ratio of 2.
The dandruff removing agent is GANBAOSU.
The nutritional agent is oat polypeptide ExtRaCt (INCNI name: PRuNuS PERSICA (PEaCH) FlowER Extra Ct, Beijing Sanyou Huizhi Biotech Co., Ltd.).
The antiseptic is Kathon.
The conditioner is polyquaternium-10.
The chelating agent is disodium EDTA.
The pH regulator is citric acid and sodium citrate.
The pearling agent is ethylene glycol monostearate.
Example 2:
a formula of a liquid shampoo is provided,
3.6 parts of hair-moistening grease, 35 parts of surfactant, 1.8 parts of thickening agent, 0.9 part of anti-dandruff agent, 1.6 parts of nutritional agent, 0.47 part of preservative, 0.43 part of conditioner, 0.09 part of chelating agent, 2 parts of pH regulator, 1.8 parts of pearling agent and 67 parts of water.
The hair oil is emulsified silicone oil, the emulsified silicone oil comprises large-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand) and small-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand), and the mass ratio of the large-particle-size emulsified silicone oil to the small-particle-size emulsified silicone oil is 1: 2 in the ratio.
The surfactant comprises a main surfactant sodium laureth sulfate (70%), a cosurfactant cocamidopropyl betaine (30%) and a functional agent, wherein the main surfactant and the cosurfactant are mixed in a mass ratio of 4: 1, the functional agent comprises diosmetin-7-O-glucoside and isoxarotenone, the dosage of the diosmetin-7-O-glucoside is 3.6wt% of the main surface active agent, and the dosage of the isoxarotenone is 4.2wt% of the main surface active agent.
The thickening agent is a mixture of cocamide MEA and PEG-150 distearate, wherein the weight ratio of the cocamide MEA to the PEG-150 distearate is 1: 2, and mixing the components.
The dandruff removing agent is GANBAOSU.
The nutritional agent is oat polypeptide ExtRaCt (INCNI name: PRuNuS PERSICA (PEaCH) FlowER Extra Ct, Beijing Sanyou Huizhi Biotech Co., Ltd.).
The antiseptic is Kathon.
The conditioner is polyquaternium-10.
The chelating agent is disodium EDTA.
The pH regulator is citric acid and sodium citrate.
The pearling agent is ethylene glycol monostearate.
Example 3:
a formula of a liquid shampoo is provided,
3 parts of hair oil, 28 parts of surfactant, 1.5 parts of thickening agent, 0.6 part of anti-dandruff agent, 1.2 parts of nutritional agent, 0.3 part of preservative, 0.25 part of conditioner, 0.06 part of chelating agent, 2 parts of pH regulator, 1.5 parts of pearling agent and 60 parts of water.
The hair oil is emulsified silicone oil, the emulsified silicone oil comprises large-particle-size emulsified silicone oil (the content of silicone oil is 60 percent, and the internal phase viscosity is 30-100 ten thousand) and small-particle-size emulsified silicone oil (the content of silicone oil is 60 percent, and the internal phase viscosity is 30-100 ten thousand), and the mass ratio of the large-particle-size emulsified silicone oil to the small-particle-size emulsified silicone oil is 1: 2 in the ratio.
The surfactant comprises a main surfactant sodium laureth sulfate (70%), a cosurfactant cocamidopropyl betaine (30%) and a functional agent, wherein the main surfactant and the cosurfactant are mixed in a mass ratio of 4: 1, the functional agent comprises diosmetin-7-O-glucoside and isoxarotenone, the using amount of the diosmetin-7-O-glucoside is 2wt% of the main surface active agent, and the using amount of the isoxarotenone is 3.5wt% of the main surface active agent.
The thickening agent is a mixture of cocamide MEA and PEG-150 distearate, wherein the weight ratio of the cocamide MEA to the PEG-150 distearate is 1: 2 in a ratio of 2.
The dandruff removing agent is GANBAOSU.
The nutritional agent is oat polypeptide ExtRaCt (INCNI name: PRuNuS PERSICA (PEaCH) FlowER Extra Ct, Beijing Sanyou Huizhi Biotech Co., Ltd.).
The antiseptic is Kathon.
The conditioner is polyquaternium-10.
The chelating agent is disodium EDTA.
The pH regulator is citric acid and sodium citrate.
The pearling agent is ethylene glycol monostearate.
Example 4:
a formula of a shampoo is provided,
3 parts of hair oil, 28 parts of surfactant, 1.5 parts of thickening agent, 0.6 part of anti-dandruff agent, 1.2 parts of nutritional agent, 0.3 part of preservative, 0.25 part of conditioner, 0.06 part of chelating agent, 2 parts of pH regulator, 1.5 parts of pearling agent and 60 parts of water.
The hair oil is emulsified silicone oil, the emulsified silicone oil comprises large-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand) and small-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand), and the mass ratio of the large-particle-size emulsified silicone oil to the small-particle-size emulsified silicone oil is 1: 2 in the ratio.
The surfactant comprises a main surfactant sodium laureth sulfate (70%), a cosurfactant cocamidopropyl betaine (30%) and a functional agent, wherein the main surfactant and the cosurfactant are mixed in a mass ratio of 4: 1, the functional agent comprises diosmetin-7-O-glucoside and isoxarotenone, the dosage of the diosmetin-7-O-glucoside is 2wt% of the main surface active agent, and the dosage of the isoxarotenone is 3.5wt% of the main surface active agent.
The thickening agent is a mixture of cocamide MEA and PEG-150 distearate, wherein the weight ratio of the cocamide MEA to the PEG-150 distearate is 1: 2, and mixing the components.
The nutritional agent is oat polypeptide ExtRaCt (INCNI name: PRuNuS PERSICA (PEaCH) FlowER Extra Ct, Beijing Sanyou Huizhi Biotech Co., Ltd.).
The antiseptic is Kathon.
The conditioner is polyquaternium-10.
The conditioner also contains Z-D-arginine hydrochloride and choline bitartrate, wherein the addition amount of the Z-D-arginine hydrochloride is 1.2wt% of the polyquaternium-10, and the addition amount of the choline bitartrate is 0.8wt% of the polyquaternium-10.
The chelating agent is disodium EDTA.
The pH regulator is citric acid and sodium citrate.
The pearling agent is ethylene glycol monostearate.
Example 5:
a formula of a shampoo is provided,
3 parts of hair oil, 28 parts of surfactant, 1.5 parts of thickening agent, 0.6 part of anti-dandruff agent, 1.2 parts of nutritional agent, 0.3 part of preservative, 0.25 part of conditioner, 0.06 part of chelating agent, 2 parts of pH regulator, 1.5 parts of pearling agent and 60 parts of water.
The hair oil is emulsified silicone oil, the emulsified silicone oil comprises large-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand) and small-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand), and the mass ratio of the large-particle-size emulsified silicone oil to the small-particle-size emulsified silicone oil is 1: 2 in the ratio.
The surfactant comprises a main surfactant sodium laureth sulfate (70%), a cosurfactant cocamidopropyl betaine (30%) and a functional agent, wherein the main surfactant and the cosurfactant are mixed in a mass ratio of 4: 1, the functional agent comprises diosmetin-7-O-glucoside and isoxarotenone, the dosage of the diosmetin-7-O-glucoside is 2wt% of the main surface active agent, and the dosage of the isoxarotenone is 3.5wt% of the main surface active agent.
The thickening agent is a mixture of cocamide MEA and PEG-150 distearate, wherein the weight ratio of the cocamide MEA to the PEG-150 distearate is 1: 2 in a ratio of 2.
The nutritional agent is oat polypeptide ExtRaCt (INCNI name: PRuNuS PERSICA (PEaCH) FlowER Extra Ct, Beijing Sanyou Huizhi Biotech Co., Ltd.).
The antiseptic is Kathon.
The conditioner is polyquaternium-10.
The conditioner also contains Z-D-arginine hydrochloride and choline bitartrate, wherein the addition amount of the Z-D-arginine hydrochloride is 2.5wt% of the polyquaternium-10, and the addition amount of the choline bitartrate is 2.1wt% of the polyquaternium-10.
The chelating agent is disodium EDTA.
The pH regulator is citric acid and sodium citrate.
The pearling agent is ethylene glycol monostearate.
Example 6:
a formula of a shampoo is provided,
3 parts of hair oil, 28 parts of surfactant, 1.5 parts of thickening agent, 0.6 part of anti-dandruff agent, 1.2 parts of nutritional agent, 0.3 part of preservative, 0.25 part of conditioner, 0.06 part of chelating agent, 2 parts of pH regulator, 1.5 parts of pearling agent and 60 parts of water.
The hair oil is emulsified silicone oil, the emulsified silicone oil comprises large-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand) and small-particle-size emulsified silicone oil (the content of silicone oil is 60%, the internal phase viscosity is 30-100 ten thousand), and the mass ratio of the large-particle-size emulsified silicone oil to the small-particle-size emulsified silicone oil is 1: 2 in the ratio.
The surfactant comprises a main surfactant sodium laureth sulfate (70%), a cosurfactant cocamidopropyl betaine (30%) and a functional agent, wherein the main surfactant and the cosurfactant are mixed in a mass ratio of 4: 1, the functional agent comprises diosmetin-7-O-glucoside and isoxarotenone, the dosage of the diosmetin-7-O-glucoside is 2wt% of the main surface active agent, and the dosage of the isoxarotenone is 3.5wt% of the main surface active agent.
The thickening agent is a mixture of cocamide MEA and PEG-150 distearate, wherein the weight ratio of the cocamide MEA to the PEG-150 distearate is 1: 2, and mixing the components.
The nutritional agent is oat polypeptide ExtRaCt (INCNI name: PRuNuS PERSICA (PEaCH) FlowER Extra Ct, Beijing Sanyou Huizhi Biotech Co., Ltd.).
The antiseptic is Kathon.
The conditioner is polyquaternium-10.
The conditioner also contains Z-D-arginine hydrochloride and choline bitartrate, wherein the addition amount of the Z-D-arginine hydrochloride is 1.6wt% of the polyquaternium-10, and the addition amount of the choline bitartrate is 1.8wt% of the polyquaternium-10.
The chelating agent is disodium EDTA.
The pH regulator is citric acid and sodium citrate.
The pearling agent is ethylene glycol monostearate.
Comparative example 1:
this comparative example is different from example 3 only in that isoxarotene is not added to the surfactant.
Comparative example 2:
this comparative example is compared to example 3, except that no diosmetin-7-O-glucoside was added to the surfactant.
Comparative example 3:
this comparative example is compared to example 3, except that no diosmetin-7-O-glucoside and isoxagin were added to the surfactant.
Comparative example 4:
this comparative example is compared to example 6, except that choline bitartrate was not added to the surfactant.
Comparative example 5:
this comparative example is compared to example 6, except that no Z-D-arginine hydrochloride was added to the surfactant.
Test example 1:
the conventional process comprises the following steps: heating water to 85 ℃, adding a surfactant and a chelating agent while stirring, and dissolving; cooling to 60 deg.C, sequentially adding hair oil, thickener and dandruff removing agent, and stirring; cooling to 45 deg.C, sequentially adding nutritional agent, antiseptic, conditioner, pH regulator, and pearling agent, and stirring.
1. Foam test
Test samples: the shampoo obtained by the formulation of each example and comparative example is prepared according to the conventional process.
Preheating a constant-temperature water bath to 40 ℃, and opening a water circulation to preheat the Roche foamer to 40 ℃.
2.5g of the test sample was weighed, dissolved in 100ml of 1500mg/kg hard water (0.0999 g of calcium chloride, 0.148g of magnesium sulfate, constant volume 1000ml volumetric flask), transferred to a 1000ml glass flask, added with distilled water to the scale mark, and placed in a 40 ℃ for heating and aging for 30 min. And (3) washing the inner wall of the graduated tube by using the aged test solution, injecting the test solution from the bottom of the graduated tube to a position above a 50ml graduation line, closing a cock of the graduated tube, standing for 5min, and adjusting the liquid level to the position of the 50ml graduation line. The dropping tube is filled with 200ml of test solution by a suction method, and is fixed above the graduated tube by a clamp, so that the outlet of the dropping tube reaches the 900mm position at the upper end of the graduated tube, and the outlet of the dropping tube is positioned at the center of the graduated tube. The dropper was opened and a timer was started when the test solution had run out and the average height of the foam in the gate was read, recorded as the average height of the foam edge and apex, and read a second time at the end of 5 min. This procedure was repeated 2 times with new test solution, and the inner wall of the graduated tube was rinsed with test solution before each test. Care was taken to ensure that the height of each drop was the same.
The foam test results are shown in FIG. 1, where the highest foam height of example 5, up to 175mm, indicates good foaming performance, and the lowest foam height of comparative example 3, up to 135mm, indicates the worst foaming performance; examples 1-2 compared to example 3 show that the performance of shampoos of different formulations do not differ much; example 3 compared to comparative example 3, it is shown that the use of diosmetin-7-O-glucoside and isoxatilin together improves the foaming properties of the shampoo; example 3 compared to comparative examples 1-2, it is shown that the co-use of diosmetin-7-O-glucoside and isoxarotenone is superior to the use of diosmetin-7-O-glucoside or isoxarotenone alone; compared with the comparative example 3, the comparative examples 1-2 show that the single use of diosmetin-7-O-glucoside or isoxarin can improve the foaming performance of the shampoo; examples 4-6 show that the combination of Z-D-arginine hydrochloride and choline bitartrate further improves the foaming properties of the shampoo compared with example 3; comparative examples 4-5 compared to example 3, show that the use of Z-D-arginine hydrochloride or choline bitartrate alone does not substantially improve the foaming properties of the shampoo; example 6 compared with comparative examples 4-5, it is shown that the foaming performance of the shampoo can be remarkably improved only when the Z-D-arginine hydrochloride and the choline bitartrate are used together.
After standing for 5min after foaming, the foam stability is represented by a foam height reduction rate after detection again, the test result is shown in fig. 2, the foam height reduction rate of the example 5 is the smallest and reaches 0.57%, which indicates that the stability is the best, and the foam height reduction rate of the comparative example 3 is the highest and reaches 2.96%, which indicates that the stability is the weakest; examples 1-2 compared to example 3 show that the performance of shampoos of different formulations do not differ much; example 3 compared to comparative example 3, it is shown that the co-use of diosmetin-7-O-glucoside and isoxatilin improves the foaming stability of the shampoo; example 3 compared to comparative examples 1-2, it is shown that the co-use of diosmetin-7-O-glucoside and isoxarotenone is superior to the use of diosmetin-7-O-glucoside or isoxarotenone alone; comparison of comparative examples 1-2 with comparative example 3 shows that the single use of diosmetin-7-O-glucoside or isoxatilin can improve the foaming stability of the shampoo; examples 4-6 show that the combination of Z-D-arginine hydrochloride and choline bitartrate further improves the foaming stability of the shampoo compared with example 3; comparative examples 4-5 compared to example 3, show that the use of Z-D-arginine hydrochloride or choline bitartrate alone has substantially no effect on the foaming properties of the shampoo; example 6 compared to comparative examples 4-5, it is shown that Z-D-arginine hydrochloride and choline bitartrate are more effective in enhancing shampoo lathering.
In a foam test of the shampoo, the foam height reaches more than 140mm, and the foam height reduction rate is below 2% after 5 min.
2. Shampoo washing performance test of hair bundle
Test samples: the shampoo obtained by the formulation of each example and comparative example is prepared according to the conventional process.
Hair strand preparation
Hair strands (50 cm in length and about 20g in weight) were prepared, washed with tap water at 40 ℃ twice, rubbed together, and dried.
5g of sodium dodecyl sulfate was weighed and dissolved in a 1000mL beaker and heated to 75 ℃. Then the tresses are soaked in a beaker and placed in a constant temperature and humidity box at 45 ℃ for two hours. Taking out the hair bundle, gently kneading for a moment, washing with tap water, blowing to be semi-dry at a position 20cm away from the hair bundle by using a blower, and finally naturally drying.
Hair bundle compliance test
Taking 5g of shampoo sample to be tested, smearing the shampoo sample on hair bundles, rubbing for two minutes until rich foam is generated, standing for five minutes, then washing with tap water, and naturally drying. And then placing the dried hair bundle on a friction coefficient tester, measuring the dynamic friction coefficient, measuring three times and taking an average value, wherein the smaller the numerical value is, the better the flexibility of the hair bundle is, and thus, the quality of the shampoo sample is judged.
Hair tress combing test
Weighing 5g of shampoo sample to be tested, smearing the shampoo sample on hair bundle, rubbing for two minutes until rich foam is generated, standing for five minutes, and then washing with tap water. Wiping off excessive water with towel until no water drops on hair, combing with comb, and measuring wet hair combing property with tensile tester.
Then, the hair is blown to be half-dry at a position 20cm away from the hair bundle by a blower, combed smoothly by a comb, naturally dried, and the combing property of the dried hair is tested by a universal tension tester.
The flexibility test result is shown in fig. 3, the dynamic friction coefficient of the comparative example 3 is the largest and reaches 0.124, which shows that the flexibility is poor, and the dynamic friction coefficient of the example 5 is the smallest and reaches 0.101, which shows that the flexibility is the best; examples 1-2 compared to example 3 show that the performance of shampoos of different formulations do not differ much; example 3 compared with comparative example 3, it is shown that the flexibility of the shampoo is improved by using diosmetin-7-O-glucoside and isoxatilin together; example 3 compared to comparative examples 1-2, it is shown that the use of diosmetin-7-O-glucoside and isoxagin together is superior to the use of diosmetin-7-O-glucoside or isoxagin alone; compared with the comparative example 3, the comparative examples 1-2 show that the flexibility of the shampoo can be improved by using diosmetin-7-O-glucoside or isoxarin singly; examples 4-6 show that the use of Z-D-arginine hydrochloride and choline bitartrate further improves the flexibility of the shampoo compared with example 3; comparative examples 4-5 compared to example 3, show that the use of Z-D-arginine hydrochloride or choline bitartrate alone can slightly improve the flexibility of the shampoo; example 6 shows that the use of Z-D-arginine hydrochloride and choline bitartrate further improves shampoo pliability when compared to comparative examples 4-5.
The wet combing test results are shown in fig. 4, with the friction force of example 5 being the lowest and 2.04N, indicating the best wet combing of the shampoo, and the friction force of comparative example 3 being the highest and 2.56N, indicating the worst wet combing; examples 1-2 compared to example 3 show that the performance of shampoos of different formulations do not differ much; example 3 compared to comparative example 3, it is shown that the use of diosmetin-7-O-glucoside and isoxatilin together improves the wet combing properties of the shampoo; example 3 compared to comparative examples 1-2, it is shown that the use of diosmetin-7-O-glucoside and isoxagin together is superior to the use of diosmetin-7-O-glucoside or isoxagin alone; comparative examples 1-2 compared to comparative example 3, show that the single use of diosmetin-7-O-glucoside or isoxarin can improve the wet combing property of the shampoo; examples 4-6 show that the co-use of Z-D-arginine hydrochloride and choline bitartrate can further improve the wet combing property of the shampoo compared with example 3; comparative examples 4-5 compared to example 3, show that the use of Z-D-arginine hydrochloride or choline bitartrate alone can slightly improve the wet combing property of the shampoo; example 6 shows that the use of Z-D-arginine hydrochloride and choline bitartrate further improves the wet combing properties of shampoo compared to comparative examples 4-5.
The dry combing test results are shown in fig. 5, with example 5 having the lowest friction of 1.08N, indicating the best dry combing, and comparative example 3 having the highest friction of 1.63N, indicating the worst dry combing; examples 1-2 compared to example 3 show that the performance of shampoos of different formulations do not differ much; example 3 compared to comparative example 3, it is shown that the co-use of diosmetin-7-O-glucoside and isoxarin improves the dry combing properties of the shampoo; example 3 compared to comparative examples 1-2, it is shown that the co-use of diosmetin-7-O-glucoside and isoxarotenone is superior to the use of diosmetin-7-O-glucoside or isoxarotenone alone; comparative examples 1-2 compared to comparative example 3, show that the single use of diosmetin-7-O-glucoside or isoxarin can improve the dry combing property of the shampoo; examples 4-6 show that the co-use of Z-D-arginine hydrochloride and choline bitartrate can further improve the dry combing property of the shampoo compared with example 3; comparative examples 4-5 compared to example 3, show that the use of Z-D-arginine hydrochloride or choline bitartrate alone can slightly improve the dry combing property of the shampoo; example 6 shows that the combination of Z-D-arginine hydrochloride and choline bitartrate can further improve the drying combing property of shampoo compared with comparative examples 4-5.
In the test of the shampoo after cleaning hair, the dynamic friction coefficient is below 0.12, the wet combing force is below 2.3N, and the dry combing force is below 1.5N.
3. Inspection of health indicators
The test sample was a shampoo prepared according to the formulation of example 3 by a conventional process.
The microbial index test of the prepared shampoo is carried out according to GB/T29679-2013, and the test results are shown as follows.
TABLE 1 microbiological indicators and test results
| Index item | Require to make a request for | Test results |
| Total number of colonies/(cfu/g) | ≤1000 | Meets the requirements |
| Overview of yeasts and molds/(cfu/g) | ≤100 | Meets the requirements |
| Fecal coliform bacteria/g | Cannot be detected | Meets the requirements |
| Staphylococcus aureus/g | Cannot be detected | Meets the requirements |
| Pseudomonas aeruginosa/g | Cannot be detected | Meets the requirements |
The microbial indexes of the shampoo are qualified.
4. Physical and chemical index investigation
The test sample was a shampoo prepared according to the formulation of example 3 by a conventional process.
The formulated shampoo was subjected to sensory index testing according to GB/T29679-2013, and the test results are shown below.
TABLE 2 sensory index test results
| Index (I) | Premium product | Measured index | Level of compliance |
| Appearance of the product | No foreign matter | No foreign matter | Super grade |
| Color | Meet the specified color and luster | Meets the requirements | Super grade |
| Fragrance | Qualified fragrance | Meets the requirements | Super grade |
| Heat resistance | (40 +/-1 ℃) for 24 hours, and no delamination phenomenon after room temperature recovery | Meets the requirements | Super grade |
| Cold-resistant | Keeping the temperature at (-8 +/-1 ℃) for 24 hours, and no delamination phenomenon after the room temperature is recovered | Meets the requirements | Super grade |
Test results show that the sensory indexes of the shampoo provided by the invention reach the standard and reach the grade of top-grade products.
5. Stability survey
The test sample was a shampoo prepared according to the formulation of example 3 by a conventional process.
After the shampoo is placed for a long time, the problems of layering, thickening, thinning and thickening of all components due to sedimentation caused by environmental factors can be caused. The stability of the shampoo products is mainly considered to be the heat resistance and the cold resistance of the products. The test results are shown below.
Table 3 stability test results
| Investigation item | Standing time | Require to make a request for | Examination results |
| Constant temperature of 48 |
2 months old | No delamination and no obvious change | No delamination and slight yellowing in the second month |
| Constant temperature of 40 |
2 months old | No delamination and no obvious change | No delamination and no obvious change |
| Constant temperature of 25 |
2 months old | No delamination and no obvious change | No delamination and no obvious change |
| Constant temperature of 0 DEG C | 1 month | No delamination and no obvious change | No delamination and no obvious change |
| Constant temperature of-15 DEG C | 1 week | No delamination and no obvious change | No delamination and no obvious change |
The shampoo obtained by the invention has good stability.
The above embodiments are merely illustrative, and not restrictive, and those skilled in the art can make various changes and modifications without departing from the spirit and scope of the invention. Therefore, all equivalent technical solutions also belong to the scope of the present invention, and the protection scope of the present invention should be defined by the claims.
Claims (8)
1. The application of diosmetin-7-O-glucoside and/or isoxarin in improving the foaming property, foaming stability, flexibility and combing property of shampoo is characterized in that: the shampoo contains surfactants, wherein the surfactants comprise a main surfactant, a cosurfactant and a functional agent, the main surfactant comprises sodium laureth sulfate, and the cosurfactant comprises one or a mixture of cocamidopropyl betaine, sodium lauroyl sarcosinate and decyl glucoside; the functional agent is diosmetin-7-O-glucoside and/or isoxarin; the addition amount of diosmetin-7-O-glucoside in the surfactant is 1-4wt% of the main surfactant, and the addition amount of isoxatilin is 0.5-5wt% of the main surfactant; the main surfactant and the auxiliary surfactant are mixed in a mass ratio of 4: the ratio of 1 was used.
2. Use according to claim 1, characterized in that: the addition amount of diosmetin-7-O-glucoside in the surfactant is 2wt% of the main surfactant, and the addition amount of isoxatilin is 3.5wt% of the main surfactant.
3. Use according to claim 1, characterized in that: the shampoo comprises:
the hair moistening oil is emulsified silicone oil;
thickening agent, anti-dandruff agent, nutritional agent, preservative, conditioning agent, chelating agent, pH regulator, pearling agent and water.
4. Use according to claim 3, characterized in that: the shampoo comprises the following components in parts by mass:
2-4 parts of hair-moistening grease, 20-40 parts of surfactant, 0.5-2 parts of thickener, 0.1-1 part of anti-dandruff agent, 0.3-2 parts of nutritional agent, 0.05-0.5 part of preservative, 0.1-0.5 part of conditioner, 0.03-0.1 part of chelating agent, 0.5-5 parts of pH regulator, 1-2 parts of pearling agent and 50-70 parts of water.
5. Use according to claim 3, characterized in that: the thickener comprises one or a mixture of sodium chloride, cocamide MEA, PEG-150 distearate and PPG-2 hydroxyethyl cocamide.
6. Use according to claim 3, characterized in that: the dandruff removing agent is climbazole.
7. Use according to claim 3, characterized in that: the nutritional agent is oat polypeptide extract.
8. Use according to claim 3, characterized in that: the preservative is cason.
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| CN103381137A (en) * | 2013-07-31 | 2013-11-06 | 朱耀灯 | Natural softening moisturizing shampoo composition |
| CN103819520A (en) * | 2014-02-14 | 2014-05-28 | 闻永举 | Method for preparing mono-glucoside through selective hydrolysis of flavone rutinoside or neohesperidoside |
| WO2017094905A1 (en) * | 2015-12-02 | 2017-06-08 | 金印株式会社 | Hair restoration/growth stimulating agent |
| CN108743695A (en) * | 2018-07-05 | 2018-11-06 | 乙丙丁健康产业（深圳）有限公司 | A kind of Chinese medicine composition and preparation of hair-growing and hair care |
| CN109602639A (en) * | 2019-01-31 | 2019-04-12 | 广州艾蓓生物科技有限公司 | A kind of amino pickling shield shampoo and preparation method thereof |
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2020
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103381137A (en) * | 2013-07-31 | 2013-11-06 | 朱耀灯 | Natural softening moisturizing shampoo composition |
| CN103819520A (en) * | 2014-02-14 | 2014-05-28 | 闻永举 | Method for preparing mono-glucoside through selective hydrolysis of flavone rutinoside or neohesperidoside |
| WO2017094905A1 (en) * | 2015-12-02 | 2017-06-08 | 金印株式会社 | Hair restoration/growth stimulating agent |
| CN108743695A (en) * | 2018-07-05 | 2018-11-06 | 乙丙丁健康产业（深圳）有限公司 | A kind of Chinese medicine composition and preparation of hair-growing and hair care |
| CN109602639A (en) * | 2019-01-31 | 2019-04-12 | 广州艾蓓生物科技有限公司 | A kind of amino pickling shield shampoo and preparation method thereof |
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