CN111514230A - Lung-ventilating and lung-ventilating traditional Chinese medicine capsule containing ephedra and apricot seeds and preparation method of lung-ventilating and lung-ventilating traditional Chinese medicine capsule - Google Patents
Lung-ventilating and lung-ventilating traditional Chinese medicine capsule containing ephedra and apricot seeds and preparation method of lung-ventilating and lung-ventilating traditional Chinese medicine capsule Download PDFInfo
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Abstract
The invention discloses a ephedra and apricot lung-ventilating traditional Chinese medicine capsule which is applied to acute trachea and bronchitis diseases such as acute attack of chronic bronchitis and viral respiratory inflammation; the raw materials of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule comprise ephedra, bitter apricot kernel (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, heartleaf houttuynia herb, honeysuckle or lonicera confusa and dried orange peel; the invention discovers a new medical application of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule, so that the ephedra and apricot lung-ventilating traditional Chinese medicine capsule can be applied to treating acute tracheitis, bronchitis diseases and viral respiratory inflammation such as acute attack of chronic bronchitis, can effectively relieve the symptoms of the acute tracheitis, bronchitis diseases and viral respiratory inflammation such as acute attack of chronic bronchitis and can also cure the acute tracheitis, bronchitis diseases and viral respiratory inflammation such as acute attack of chronic bronchitis.
Description
Technical Field
The invention relates to a medicament for treating influenza virus, in particular to a ephedra and apricot lung-ventilating traditional Chinese medicine capsule and a preparation method thereof.
Background
Influenza virus (inflenzavirus) is an important disease affecting human health and economic development in the 21 st century, and has increasingly negative impact on various countries and even global economy as the global economy integration develops and communication between various countries becomes more frequent. In addition, seasonal influenza, which is frequently encountered in winter and spring every year, new subtype influenza virus which comes from time to time and avian influenza virus seriously threaten the health of human beings and the development of animal husbandry.
Disclosure of Invention
The invention aims to provide a ephedra and apricot lung-ventilating traditional Chinese medicine capsule applied to a medicine for treating influenza virus and a preparation method thereof.
The technical scheme for realizing the purpose of the invention is as follows: a Chinese medicinal capsule, MAXING XUANFEI Chinese medicinal capsule, is used for treating acute tracheitis and bronchitis diseases such as acute episode of chronic bronchitis, and viral respiratory inflammation; the raw materials of the lung-ventilating ephedra and apricot kernel Chinese medicinal capsule comprise ephedra, semen armeniacae amarae (blanched), liquorice, platycodon grandiflorum, fritillaria thunbergii, houttuynia cordata, honeysuckle or lonicera confusa and dried orange peel; the preparation method of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule comprises the following steps:
the method comprises the following steps of: 100 parts of houttuynia cordata, 30-70 parts of honeysuckle or lonicera confusa, 25-45 parts of semen armeniacae amarae (blanched), 25-45 parts of platycodon grandiflorum, 20-40 parts of thunberg fritillary bulb, 15-35 parts of ephedra, 10-30 parts of dried orange peel and 8-20 parts of liquorice;
step two, extracting the thunberg fritillary bulb in proportion by using ethanol, and concentrating the extracting solution to obtain an extracting solution; collecting volatile oil of herba Houttuyniae and pericarpium Citri Tangerinae at a certain proportion, extracting with water, and concentrating the extractive solution to obtain extractive solution; extracting flos Lonicerae or flos Lonicerae, semen Armeniacae amarum (blanched), radix Platycodi, herba Ephedrae, and Glycyrrhrizae radix with water, and concentrating the extractive solution to obtain extractive solution;
step three, respectively concentrating and drying extracts of ephedra, semen armeniacae amarae (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, houttuynia cordata, lonicera confusa and dried orange peel to obtain powder of each raw material extract;
step four, placing the powder of each raw material extracting solution obtained in the step three into a three-dimensional mixing tank, and mixing for 20-30 minutes at a rotating speed of 10-20 revolutions per minute to obtain mixed powder;
putting the mixed material powder obtained in the step four into a wet granulator, adding edible ethanol, stirring and granulating to obtain wet granules of the mixed material powder;
step six, drying and cooling the wet particles of the mixed material powder obtained in the step five to obtain dry particles of the mixed material powder, and sieving to obtain dry particles of 40-60 meshes;
and step seven, filling the dry particles obtained in the step six into capsules according to the filling amount of the ephedra and apricot lung-ventilating traditional Chinese medicine capsules.
The ephedra and apricot lung-ventilating traditional Chinese medicine capsule is applied to treating viral respiratory tract inflammation, and is particularly applied to treating viral pneumonia. The viral pneumonia is novel coronavirus pneumonia.
The raw material medicaments used in the invention have the following effects:
herba ephedrae: the traditional Chinese medicine has strong efficacies of warming and sweating to relieve exterior syndrome, inducing diuresis and relieving swelling, is mainly used for treating wind-cold exterior syndrome, chest distress, cough and asthma, edema due to wind-cold, rheumatic arthralgia, deep carbuncle in the yin, phlegm nodule, and the honey ephedra has warm and moist properties, has mild pungent and sweating dispelling effects, enhances the efficacy of moistening lung and relieving cough, has the advantages of freeing lung and relieving asthma and relieving cough, and is mainly used for relieving exterior syndrome, asthma and cough.
Bitter almond (blanched): it enters lung and large intestine, has effects of lowering qi, relieving cough and asthma, loosening bowel to relieve constipation, and can be used for treating cough and asthma, fullness in chest, excessive phlegm, blood deficiency, dry body fluid, and constipation due to intestinal dryness.
Licorice root: invigorating spleen and replenishing qi, clearing heat and detoxicating, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs, and can be used for treating weakness of spleen and stomach, listlessness and debilitation, cardiopalmus and short breath, cough with excessive phlegm, abdominal cavity, limb spasm and pain, carbuncle swelling and sore toxin, and relieving drug intensity.
Balloon flower: to disperse lung qi, to help disperse hair, dispel phlegm and discharge pus to stop cough and asthma.
Thunberg fritillary bulb: clearing and resolving heat phlegm and nourishing the lung, and the alkaloid fritillaria cirrhosa essence has a protective effect on acute lung injury.
Houttuynia cordata: the effective component houttuynin can enhance phagocytic ability of leukocyte, and increase serum properdin, which is obviously increased when treating chronic tracheitis.
Wild honeysuckle flower: dispel wind-heat externally to relieve exterior pathogen and interior remove heat-toxin to relieve heat stagnation. Since ancient times, lonicera confusa is known as a holy drug for clearing heat and removing toxicity, and researches prove that the lonicera confusa contains active ingredients such as chlorogenic acid, luteolin glycoside and the like, has stronger inhibitory effect on various pathogenic bacteria such as hemolytic streptococcus, staphylococcus aureus and the like, upper respiratory infection pathogenic viruses and the like, and can also enhance immunity.
Dried orange peel: pungent and bitter with the actions of dispersing and purging, light ascending and floating, specially coordinating the qi activities of the spleen and lung to help dispersing and descending, regulating qi and relieving chest stuffiness, drying dampness and resolving phlegm.
By adopting the technical scheme, the invention has the following beneficial effects: the invention discovers a new medical application of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule, so that the ephedra and apricot lung-ventilating traditional Chinese medicine capsule can be applied to treating acute tracheitis, bronchitis diseases and viral respiratory inflammation such as acute attack of chronic bronchitis, can effectively relieve the symptoms of acute tracheitis, bronchitis diseases and viral respiratory inflammation such as acute attack of chronic bronchitis and can also cure acute tracheitis, bronchitis diseases and viral respiratory inflammation such as acute attack of chronic bronchitis.
Detailed Description
Example one
The ephedra and apricot lung-ventilating traditional Chinese medicine capsule is applied to treating influenza virus, and is applied to acute trachea and bronchitis diseases such as acute attack of chronic bronchitis and the like. The lung-ventilating ephedra and apricot kernel Chinese medicinal capsule is prepared from ephedra, bitter apricot kernel (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, heartleaf houttuynia herb, honeysuckle or lonicera confusa and dried orange peel.
And (3) observation of clinical experiments: the invention carries out clinical observation and treatment on 300 patients, wherein the patients are male and female in all ages, the patients with the largest age are 80 years old, and the patients with the smallest age are only 16 years old, and are all acute attack symptoms of chronic bronchitis. The treatment method comprises the following steps: the ephedra and apricot lung-ventilating traditional Chinese medicine capsule is orally taken once a day, and 7 days are a treatment course.
The evaluation standard of curative effect is as follows:
and (3) curing: the clinical symptoms and physical signs disappear, the functional activities return to normal, and the indexes return to normal after being checked.
Improvement: the clinical symptoms are obviously improved or improved, and each index is slightly improved after the examination.
And (4) invalidation: the clinical symptoms and signs are not improved, and the examination indexes are not improved.
The treatment effect is as follows: clinical research results of a plurality of three hospitals, namely a first auxiliary hospital of western medicine university, a Hunan elegant hospital of China-south university, an auxiliary hospital of China medical research institute in Hunan province, a traditional Chinese medicine institute in Hunan province and the like show that: overall efficacy in 300 treatment groups: the significant efficiency is 65.00 percent, the effective rate is 95.00 percent, and the traditional Chinese medicine symptom curative effect is as follows: the significant efficiency is 60.00 percent, and the effective rate is 87.50 percent.
Example two
The ephedra and apricot lung-ventilating traditional Chinese medicine capsule is used for treating viral respiratory tract inflammation, and the ephedra and apricot lung-ventilating traditional Chinese medicine capsule is used for treating viral respiratory tract inflammation. The lung-ventilating ephedra and apricot kernel Chinese medicinal capsule is prepared from ephedra, bitter apricot kernel (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, heartleaf houttuynia herb, honeysuckle or lonicera confusa and dried orange peel.
The ephedra and apricot lung-ventilating traditional Chinese medicine capsule is applied to treating viral respiratory tract inflammation, and is particularly applied to treating viral pneumonia. Viral pneumonia is a novel coronavirus pneumonia.
The raw material medicaments used in the invention have the following effects:
herba Ephedrae. The traditional Chinese medicine has strong efficacies of warming and sweating to relieve exterior syndrome, inducing diuresis and relieving swelling, is mainly used for treating wind-cold exterior syndrome, chest distress, cough and asthma, edema due to wind-cold, rheumatic arthralgia, deep carbuncle in the yin, phlegm nodule, and the honey ephedra has warm and moist properties, has mild pungent and sweating dispelling effects, enhances the efficacy of moistening lung and relieving cough, has the advantages of freeing lung and relieving asthma and relieving cough, and is mainly used for relieving exterior syndrome, asthma and cough.
Bitter apricot kernel (blanched). It enters lung and large intestine, has effects of lowering qi, relieving cough and asthma, loosening bowel to relieve constipation, and can be used for treating cough and asthma, fullness in chest, excessive phlegm, blood deficiency, dry body fluid, and constipation due to intestinal dryness.
Licorice root: invigorating spleen and replenishing qi, clearing heat and detoxicating, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs, and can be used for treating weakness of spleen and stomach, listlessness and debilitation, cardiopalmus and short breath, cough with excessive phlegm, abdominal cavity, limb spasm and pain, carbuncle swelling and sore toxin, and relieving drug intensity.
Balloon flower: to disperse lung qi, to help disperse hair, dispel phlegm and discharge pus to stop cough and asthma.
Thunberg fritillary bulb: clearing and resolving heat phlegm and nourishing the lung, and the alkaloid fritillaria cirrhosa essence has a protective effect on acute lung injury.
Houttuynia cordata: the effective component houttuynin can enhance phagocytic ability of leukocyte, and increase serum properdin, which is obviously increased when treating chronic tracheitis.
Wild honeysuckle flower: dispel wind-heat externally to relieve exterior pathogen and interior remove heat-toxin to relieve heat stagnation. Since ancient times, lonicera confusa is known as a holy drug for clearing heat and removing toxicity, and researches prove that the lonicera confusa contains active ingredients such as chlorogenic acid, luteolin glycoside and the like, has stronger inhibitory effect on various pathogenic bacteria such as hemolytic streptococcus, staphylococcus aureus and the like, upper respiratory infection pathogenic viruses and the like, and can also enhance immunity.
Dried orange peel: pungent and bitter with the actions of dispersing and purging, light ascending and floating, specially coordinating the qi activities of the spleen and lung to help dispersing and descending, regulating qi and relieving chest stuffiness, drying dampness and resolving phlegm.
The application of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule in the treatment of the novel coronary virus pneumonia is studied by taking the ephedra and apricot lung-ventilating traditional Chinese medicine capsule in the embodiment as an example.
1. Experimental materials and methods of administration: 10 Kunming mice of 18-22g which were positive in nucleic acid detection were prepared. The ephedra and apricot lung-ventilating traditional Chinese medicine capsule of the embodiment is soaked in water to obtain a concentrated medicament, and each white mouse is irrigated with 4g of the concentrated medicament every day.
2. And (3) experimental observation: the observation period is 15 days, wherein CT lung imaging shooting is carried out on the mice every three days, and lung disease grouping is observed according to the CT imaging shooting, the mice with white spots on the lungs are grouped into an uncured group, the mice with no white spots on the lungs are grouped into a cured group, the administration of the drug in the cured group is stopped, the nucleic acid detection is carried out again, and the drug administration of the uncured group is continued and the observation is continued.
3. The experimental results are as follows: the experiment was carried out for 16 days, and 9 surviving mice were treated in the cured group, and 1 dead mouse was treated in the non-cured group.
EXAMPLE III
The preparation method of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule comprises the following steps:
the method comprises the following steps of: 100 parts of houttuynia cordata, 30-70 parts of honeysuckle or lonicera confusa, 25-45 parts of semen armeniacae amarae (blanched), 25-45 parts of platycodon grandiflorum, 20-40 parts of thunberg fritillary bulb, 15-35 parts of ephedra, 10-30 parts of dried orange peel and 8-20 parts of liquorice;
step two, extracting the thunberg fritillary bulb in proportion by using ethanol, and concentrating the extracting solution to obtain an extracting solution; collecting volatile oil of herba Houttuyniae and pericarpium Citri Tangerinae at a certain proportion, extracting with water, and concentrating the extractive solution to obtain extractive solution; extracting flos Lonicerae or flos Lonicerae, semen Armeniacae amarum (blanched), radix Platycodi, herba Ephedrae, and Glycyrrhrizae radix with water, and concentrating the extractive solution to obtain extractive solution;
step three, respectively concentrating and drying extracts of ephedra, semen armeniacae amarae (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, houttuynia cordata, lonicera confusa and dried orange peel to obtain powder of each raw material extract;
step four, placing the powder of each raw material extracting solution obtained in the step three into a three-dimensional mixing tank, and mixing for 20-30 minutes at a rotating speed of 10-20 revolutions per minute to obtain mixed powder;
putting the mixed material powder obtained in the step four into a wet granulator, adding edible ethanol, stirring and granulating to obtain wet granules of the mixed material powder;
step six, drying and cooling the wet particles of the mixed material powder obtained in the step five to obtain dry particles of the mixed material powder, and sieving to obtain dry particles of 40-60 meshes;
and step seven, filling the dry particles obtained in the step six into capsules according to the filling amount of the ephedra and apricot lung-ventilating traditional Chinese medicine capsules.
The above-mentioned embodiments are intended to illustrate the objects, technical solutions and advantages of the present invention in further detail, and it should be understood that the above-mentioned embodiments are only exemplary embodiments of the present invention and are not intended to limit the present invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (3)
1. The ephedra and apricot lung-ventilating traditional Chinese medicine capsule is characterized in that: the ephedra and apricot lung-ventilating traditional Chinese medicine capsule is applied to acute trachea and bronchitis diseases such as acute attack of chronic bronchitis and the like and viral respiratory inflammation; the raw materials of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule comprise ephedra, bitter apricot kernel (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, heartleaf houttuynia herb, honeysuckle or lonicera confusa and dried orange peel; the preparation method of the ephedra and apricot lung-ventilating traditional Chinese medicine capsule comprises the following steps:
the method comprises the following steps of: 100 parts of houttuynia cordata, 30-70 parts of honeysuckle or lonicera confusa, 25-45 parts of semen armeniacae amarae (blanched), 25-45 parts of platycodon grandiflorum, 20-40 parts of thunberg fritillary bulb, 15-35 parts of ephedra, 10-30 parts of dried orange peel and 8-20 parts of liquorice;
step two, extracting the thunberg fritillary bulb in proportion by using ethanol, and concentrating the extracting solution to obtain an extracting solution; collecting volatile oil of herba Houttuyniae and pericarpium Citri Tangerinae at a certain proportion, extracting with water, and concentrating the extractive solution to obtain extractive solution; extracting flos Lonicerae or flos Lonicerae, semen Armeniacae amarum (blanched), radix Platycodi, herba Ephedrae, and Glycyrrhrizae radix with water, and concentrating the extractive solution to obtain extractive solution;
step three, respectively concentrating and drying extracts of ephedra, semen armeniacae amarae (blanched), liquorice, platycodon grandiflorum, thunberg fritillary bulb, houttuynia cordata, lonicera confusa and dried orange peel to obtain powder of each raw material extract;
step four, placing the powder of each raw material extracting solution obtained in the step three into a three-dimensional mixing tank, and mixing for 20-30 minutes at a rotating speed of 10-20 revolutions per minute to obtain mixed powder;
putting the mixed material powder obtained in the step four into a wet granulator, adding edible ethanol, stirring and granulating to obtain wet granules of the mixed material powder;
step six, drying and cooling the wet particles of the mixed material powder obtained in the step five to obtain dry particles of the mixed material powder, and sieving to obtain dry particles of 40-60 meshes;
and step seven, filling the dry particles obtained in the step six into capsules according to the filling amount of the ephedra and apricot lung-ventilating traditional Chinese medicine capsules.
2. The ephedra-apricot lung-ventilating traditional Chinese medicine capsule as claimed in claim 1, is characterized in that: the ephedra and apricot lung-ventilating traditional Chinese medicine capsule is applied to viral respiratory inflammation, and is particularly applied to treating viral pneumonia.
3. The ephedra-apricot lung-ventilating traditional Chinese medicine capsule as claimed in claim 3, is characterized in that: the viral pneumonia is novel coronavirus pneumonia.
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| CN113995821A (en) * | 2021-10-26 | 2022-02-01 | 首都医科大学附属北京地坛医院 | Traditional Chinese medicine composition and preparation for treating novel coronavirus and pneumonia of other viruses and preparation method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049424A (en) * | 2006-04-03 | 2007-10-10 | 湖南中达骛马制药有限责任公司 | Medication for treating infection in respiratory system |
| CN104623332A (en) * | 2015-02-12 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine preparation for treating pediatric pulmonary pneumonia and preparation method thereof |
| CN106806664A (en) * | 2015-11-29 | 2017-06-09 | 宋淑芹 | A kind of Chinese medicine preparation for treating infantile pneumonia and preparation method thereof |
-
2020
- 2020-05-18 CN CN202010421029.2A patent/CN111514230A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049424A (en) * | 2006-04-03 | 2007-10-10 | 湖南中达骛马制药有限责任公司 | Medication for treating infection in respiratory system |
| CN104623332A (en) * | 2015-02-12 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine preparation for treating pediatric pulmonary pneumonia and preparation method thereof |
| CN106806664A (en) * | 2015-11-29 | 2017-06-09 | 宋淑芹 | A kind of Chinese medicine preparation for treating infantile pneumonia and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 米内网: "独家新药抗肺炎，麻杏宣肺颗粒瞄准下个十年", 《HTTPS://WWW.SOHU.COM/A/372752783_293363，【焦点】独家新药抗肺炎，麻杏宣肺颗粒瞄准下个十年》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113995821A (en) * | 2021-10-26 | 2022-02-01 | 首都医科大学附属北京地坛医院 | Traditional Chinese medicine composition and preparation for treating novel coronavirus and pneumonia of other viruses and preparation method |
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Application publication date: 20200811 |