CN102091191B - Medicament for treating chronic pharyngitis - Google Patents
Medicament for treating chronic pharyngitis Download PDFInfo
- Publication number
- CN102091191B CN102091191B CN2011100411397A CN201110041139A CN102091191B CN 102091191 B CN102091191 B CN 102091191B CN 2011100411397 A CN2011100411397 A CN 2011100411397A CN 201110041139 A CN201110041139 A CN 201110041139A CN 102091191 B CN102091191 B CN 102091191B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicine
- medicament
- crude drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a medicament for treating chronic pharyngitis, which comprises the following components in part by weight: 10 to 15 parts of great burdock achene, 10 to 15 parts of blackberrykiky rhizome, 10 to 30 parts of vietnamese sophora root, 8 to 10 parts of mint, 8 to 30 parts of honeysuckle, 10 to 30 parts of weeping forsythia, 10 to 15 parts of platycodon root, 10 to 15 parts of baicalin, 10 to 30 parts of rehmanniae praeparatum, 10 to 15 parts of cortex moutan, 10 to 30 parts of raw astragalus, 8 to 12 parts of boat-fruited scaphium seed, 8 to 10 parts of puff-ball and 3 to 5 parts of liquoric root. The medicament can be prepared into common formulations for oral administration, has the effects of dispelling wind and heat, clearing heat, detoxicating, freeing lung, promoting eruption, relieving sore throat, eliminating stagnation, relieving cough and eliminating phlegm, is suitable for treating the chronic pharyngitis, has good curative effect, prevents relapse and has a 100 percent cure rate.
Description
Technical field
The present invention relates to a kind of medicine, particularly relate to a kind of Chinese medicine preparation of treating chronic pharyngolaryngitis and preparation method thereof.
Background technology
Chronic pharyngolaryngitis is the pharyngeal pathological changes of the caused diffusivity of chronic infection, mainly is the pharyngeal mucosa inflammation, is a kind of common disease that is mainly in most of crowds.Life regional climate is cold, dry, and the working environment air is polluted by dust, chemical gas, and tobacco and wine, pungent diet long-time stimulus etc. all are prone to cause chronic pharyngolaryngitis.In addition, it is irregular to live for a long time, and tired, psychentonia descend passive protective physical fitness, and antibacterial and virus repeated infection easily also cause pharyngolaryngitis easily.Acute pharyngolaryngitis shows effect repeatedly, can transfer to chronic.Sickness rate among the urbanite accounts for about 10% to 20% of laryngopharyngeal diseases.Because of its course of disease is long, symptom is obstinate, and the short-term difficulty is seen produce effects, so be difficult for curing.
The clinical symptoms of chronic pharyngolaryngitis generally is the pharyngeal foreign body sensation that has, the hypodynia of having an itch, dryness and heat etc.; Often have thick secretions to invest not easy-clear of pharynx rear wall, night, more so " uttering a sound or a word " uttered a word, and was intended to remove then fast.Secretions can cause irritable cough, even feel sick, vomit.
At present; The medicine of China's treatment chronic pharyngolaryngitis is more, and Chinese medicine commonly used has spray, granule and the pill of selling on the market etc., though these similar medicines all have certain therapeutic effect; But have can the respite chronic pharyngolaryngitis symptom; The effect of just playing interim performance drug effect that has, have discontinue medication after also to have the recurrence ratio higher, thereby can not play the effect of effecting a permanent cure.
And the Western medicine that generally uses at present more or less all have some side effect, and its curative effect is very not satisfactory yet when the treatment chronic pharyngolaryngitis.
Summary of the invention
The purpose of this invention is to provide a kind of treatment chronic pharyngolaryngitis good effect, have no the medicine of toxic and side effects.
A kind of medicine of treating chronic pharyngolaryngitis, it is that Chinese medicine by following portions by weight is the medicament that crude drug prepares:
Fructus Arctii 10-15 Rhizoma Belamcandae 10-15 Radix Sophorae Tonkinensiss 10-30
Herba Menthae 8-10 Flos Loniceraes 8-30 Fructus Forsythiaes 10-30
Radix Platycodonis 10-15 Radix Scutellariaes 10-15 Radix Rehmanniae 10-30
Cortex Moutan 10-15 Radix Astragali 10-30 Semen Sterculiae Lychnophoraes 8-12
Lasiosphaera Seu Calvatia 8-10 Radix Glycyrrhizaes 3-5.
Medicine of the present invention further is to be the medicament that crude drug prepares with following parts by weight of traditional Chinese medicines:
Fructus Arctii 10-12 Rhizoma Belamcandae 10-12 Radix Sophorae Tonkinensiss 10-15
Herba Menthae 8-10 Flos Loniceraes 8-15 Fructus Forsythiaes 10-15
Radix Platycodonis 10-12 Radix Scutellariaes 10-12 Radix Rehmanniae 10-20
Cortex Moutan 10-12 Radix Astragali 10-30 Semen Sterculiae Lychnophoraes 8-10
Lasiosphaera Seu Calvatia 8-10 Radix Glycyrrhizaes 3-5.
Can said medicine be processed into any peroral dosage form commonly used, like powder, tablet, capsule, the watered pill, honeyed pill etc., the preferred capsule of the present invention.
The concrete method for preparing of medicine of the present invention is:
The crude drug of said parts by weight added water to just flood medicine, decocted 30 minutes after being heated to boiling point, repeat 3 times, merge 3 times decocting liquid, be condensed into 60 ℃ of relative densities after the filtration and be 1.30~1.38 thick paste, drying and crushing obtains medicine activity component.
The active component that makes is added necessary adjuvant according to the conventional formulation processing method, then can be processed into corresponding peroral dosage form, for example, in medicine activity component, add supplementary product starch, mix homogeneously is processed capsule in incapsulating.
The traditional Chinese medical science thinks, many, stagnation of phlegm blood stasis or deficiency of YIN Tianjin withered institutes scorching of chronic pharyngolaryngitis because of deficiency of YIN fire extremely, often with pharyngeal discomfort, pain gesture indistinctly, pharyngeal have that foreign body sensation, sticking amount of expectoration are few, disease such as tinnitus dim eyesight, red tongue with lack of fluid, pulse condition are counted accurately.Drug therapy chronic pharyngolaryngitis of the present invention focuses on and effects a permanent cure, and is main with relieving sore-throat by clearing away heat, Yin-nourishing and body fluid promoting, and its component Fructus Arctii, Flos Lonicerae, Radix Glycyrrhizae have dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, the effect of removing toxic substances and promoting subsidence of swelling; Rhizoma Belamcandae pathogenic fire reducing, detoxifcation, loose blood, expectorant; The detoxifcation of relieving inflammation or internal heat of Radix Sophorae Tonkinensis, Fructus Forsythiae, Radix Scutellariae, reducing swelling and alleviating pain; Herba Menthae, Lasiosphaera Seu Calvatia are used to the conjunctival congestion of having a headache, laryngopharynx swelling and pain; Radix Platycodonis has effects such as eliminating phlegm and stopping cough, evacuation of pus; The effect that the Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid; The Cortex Moutan nourishing YIN to lower pathogenic fire is separated the speckle poison, throat; The Radix Astragali can be mended the gas of the whole body, has yang invigorating concurrently, strengthening superficial resistance to stop perspiration, evacuation of pus granulation promoting, the effect of inducing diuresis to remove edema; The Semen Sterculiae Lychnophorae clearing heat and moistening lung, liyan jiedu.All medicines share, dispelling wind and heat pathogens, and the detoxifcation of relieving inflammation or internal heat, the lung qi dispersing rash, the sore-throat relieving eliminating stagnation, eliminating phlegm and stopping cough is applicable to the treatment chronic pharyngolaryngitis, good effect is difficult for recurrence.
Observe for curative effect and safety, carried out following clinical trial medicine of the present invention.
1. patient's data
150 examples are organized in treatment, wherein male 73 examples, women 77 examples.Matched group 150 examples, wherein male 82 examples, women 68 examples.
2. diagnostic criteria
Observed patient is diagnostic criteria with reference to " the clinical research guideline of new Chinese medicine treatment chronic pharyngitis " of Ministry of Public Health promulgation:
(1) YIN-deficiency of the lung and kidney: pharyngeal dried pain is uncomfortable, burning sensation, foreign body sensation, or itching throat and dry cough; Expectorant is few and sticking, and symptom is heavy towards light dusk, can have a sleepless night with hectic fever in the afternoon, fidgets due to deficiency, is hard and dry, disease such as soreness of the waist and knees, checks that pharyngeal mucosa is dark red, dry; Red tongue with lack of fluid, the few or flower stripping of tongue, thready and rapid pulse;
(2) deficiency of spleen-YANG and kidneyYANG: the throat hypodynia, the discomfort of choking, not red pneumonedema or have a little pale in the pharynx, faint low voice, lassitude, clear urine in large amounts, poor appetite, hands and feet being not warm, waist soreness, light red tongue, white, slippery and moist fur is a little less than the deep-thready pulse;
(3) phlegm-fire pent-up: foreign body in pharynx sense, expectorant adhesion sense or hypodynia, be prone to feel sick and feel sick, the thick sputum band is yellow, halitosis; Check that pharyngeal color is dark red, pachymucosa, pharynx rear wall folliculus increases even merges in bulk, and lateral pharyngeal band is plump; Body of the tongue is red partially or the ecchymosis petechia is arranged, and yellow fur is thick, thready,rolling and rapid pulse.
3. get rid of the case standard
(1) eliminating confirms by person due to some invisible pathological changes of oropharynx, nasopharynx, nose, larynx, esophagus, cervical region and whole body on inspection;
(2) gestation or women breast-feeding their children are to drug allergy person of the present invention more than 65 one full year of life below 18 one full year of life the age;
(3) be associated with serious primary disease such as cardiovascular, liver, kidney and hemopoietic system, the psychotic, do not meet the standard of including in;
(4), can't judge curative effect or data not umbra sound curative effect or safety judgement person not by the regulation medication.
4. Therapeutic Method
Matched group gives the Western medicine Yanyan slice, and three times on the one oral, each 3.The treatment group adopts capsule medicine of the present invention to treat, and every day, each was once oral sooner or later, each 2.Treatment is 2 months the course of treatment.
5. efficacy assessment standard
" the clinical research guideline of new Chinese medicine treatment chronic pharyngitis " with the Ministry of Public Health promulgation is that efficacy assessment standard carries out efficacy evaluation:
Produce effects: 2 weeks of medication did not have recurrence (catch a cold if meet, the then pharyngeal sense of discomfort time is no more than 10 days) with interior clinical symptoms and sign disappearance in 2 months with interior sx more than 1 year;
Effectively: 2 weeks of medication, 2 months with interior clinical symptoms and the disappearance of part sign with interior sx;
Invalid: symptom has slightly to alleviate or do not have and alleviates after the medication, and sign does not have obvious improvement.
6. therapeutic outcome
Treatment is organized among the 150 routine patients, produce effects 133 examples, obvious effective rate 88.7%, effective 17 examples, effective percentage 11.3%, invalid 0 example.The treatment total effective rate of medicine of the present invention reaches 100%, and effective patient is followed the tracks of, not recurrence prescription on individual diagnosis again in 1 year.Among the matched group 150 routine patients, produce effects 52 examples, obvious effective rate 34.7%, effective 38 examples, effective percentage 25.3%, invalid 60 examples, inefficiency 40%.The treatment total effective rate of contrast groups is stomach discomfort appears in 60%, 15 routine patient in drug administration process a symptom, effectively has 10 examples in 1 year, to recur prescription on individual diagnosis among the patient.
The specific embodiment
Embodiment 1
Get Fructus Arctii 20kg, Rhizoma Belamcandae 20kg, Radix Sophorae Tonkinensis 30kg, Herba Menthae 20 kg, Flos Lonicerae 60kg, Fructus Forsythiae 50kg, Radix Platycodonis 20kg, Radix Scutellariae 30 kg, the Radix Rehmanniae 40 kg, Cortex Moutan 30kg, Radix Astragali 50kg, Semen Sterculiae Lychnophorae 20kg, Lasiosphaera Seu Calvatia 20kg, Radix Glycyrrhizae 6kg.Add water and just flood Chinese medicine, be heated to behind the boiling point and decocted 30 minutes, decoct 3 times with the method; Merge 3 times decocting liquid; Be condensed into 60 ℃ of relative densities after the filtration and be 1.30~1.38 thick paste, after the drying and crushing, the active component of preparation cost invention medicine; The active component that makes is mixed with 5kg starch, process capsule in incapsulating.
Embodiment 2
Get Fructus Arctii 10kg, Rhizoma Belamcandae 15kg, Radix Sophorae Tonkinensis 15kg, Herba Menthae 9kg, Flos Lonicerae 25kg, Fructus Forsythiae 10kg, Radix Platycodonis 15kg, Radix Scutellariae 10kg, Radix Rehmanniae 20kg, Cortex Moutan 15kg, Radix Astragali 25kg, Semen Sterculiae Lychnophorae 10kg, Lasiosphaera Seu Calvatia 9kg, Radix Glycyrrhizae 3kg.Add water and just flood Chinese medicine, be heated to behind the boiling point and decocted 30 minutes, decoct 3 times with the method; Merge 3 times decocting liquid; Be condensed into 60 ℃ of relative densities after the filtration and be 1.30~1.38 thick paste, after the drying and crushing, the active component of preparation cost invention medicine; The active component that makes is mixed with 2kg starch, process capsule in incapsulating.
Claims (4)
1. medicine of treating chronic pharyngolaryngitis is characterized in that by following parts by weight of traditional Chinese medicines be the medicament that crude drug prepares:
Fructus Arctii 10-15 Rhizoma Belamcandae 10-15 Radix Sophorae Tonkinensiss 10-30
Herba Menthae 8-10 Flos Loniceraes 8-30 Fructus Forsythiaes 10-30
Radix Platycodonis 10-15 Radix Scutellariaes 10-15 Radix Rehmanniae 10-30
Cortex Moutan 10-15 Radix Astragali 10-30 Semen Sterculiae Lychnophoraes 8-12
Lasiosphaera Seu Calvatia 8-10 Radix Glycyrrhizaes 3-5.
2. the medicine of treatment chronic pharyngolaryngitis according to claim 1 is characterized in that wherein the parts by weight of each crude drug are:
Fructus Arctii 10-12 Rhizoma Belamcandae 10-12 Radix Sophorae Tonkinensiss 10-15
Herba Menthae 8-10 Flos Loniceraes 8-15 Fructus Forsythiaes 10-15
Radix Platycodonis 10-12 Radix Scutellariaes 10-12 Radix Rehmanniae 10-20
Cortex Moutan 10-12 Radix Astragali 10-30 Semen Sterculiae Lychnophoraes 8-10
Lasiosphaera Seu Calvatia 8-10 Radix Glycyrrhizaes 3-5.
3. the medicine of treatment chronic pharyngolaryngitis according to claim 1 and 2 is characterized in that described medicine is processed capsule.
4. the method for preparing of the medicine of the said treatment chronic pharyngolaryngitis of claim 3; Be in the crude drug of said parts by weight, to add water to flood crude drug, be heated to behind the boiling point and decocted 30 minutes, repeat 3 times; Merge 3 times decocting liquid; Be condensed into 60 ℃ of relative densities after the filtration and be 1.30~1.38 thick paste, drying and crushing obtains medicine activity component, adds starch and incapsulates and be prepared into capsule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011100411397A CN102091191B (en) | 2011-02-21 | 2011-02-21 | Medicament for treating chronic pharyngitis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011100411397A CN102091191B (en) | 2011-02-21 | 2011-02-21 | Medicament for treating chronic pharyngitis |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102091191A CN102091191A (en) | 2011-06-15 |
CN102091191B true CN102091191B (en) | 2012-06-20 |
Family
ID=44124570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2011100411397A Expired - Fee Related CN102091191B (en) | 2011-02-21 | 2011-02-21 | Medicament for treating chronic pharyngitis |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102091191B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102716372B (en) * | 2012-07-10 | 2014-04-16 | 李西秦 | Traditional Chinese medicine composition for curing chronic cough, and preparation method and usage thereof |
CN102872333B (en) * | 2012-10-29 | 2014-03-05 | 李福花 | Traditional Chinese medicine composition for treating pharyngitis |
CN103285230B (en) * | 2013-06-13 | 2014-09-10 | 西安新通药物研究有限公司 | Pharmaceutical composition for treating pharyngitis and preparation method thereof |
CN104208375A (en) * | 2014-09-19 | 2014-12-17 | 彭海明 | Traditional Chinese medicine preparation for treating cough |
CN107519333A (en) * | 2017-09-22 | 2017-12-29 | 陈延琼 | Treat Chinese medicine composition of pharyngitis, chronic and refractory pharyngitis and preparation method thereof |
CN108465065A (en) * | 2018-06-26 | 2018-08-31 | 桐城市泰安中药材种植专业合作社 | A kind of Chinese medicine and preparation method thereof for treating chronic hypertrophic laryngitis |
CN111991484A (en) * | 2020-09-18 | 2020-11-27 | 天津中医药大学 | A pharmaceutical composition for treating respiratory diseases in winter |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1278436A (en) * | 2000-06-07 | 2001-01-03 | 吴少伟 | Chinese medicine for acute and chronic laryngopharyngitis |
-
2011
- 2011-02-21 CN CN2011100411397A patent/CN102091191B/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1278436A (en) * | 2000-06-07 | 2001-01-03 | 吴少伟 | Chinese medicine for acute and chronic laryngopharyngitis |
Non-Patent Citations (2)
Title |
---|
张勉等.中医中药治疗慢性咽炎近况.《河北中医》.2003,第25卷(第9期),第714-716页. * |
王付.怎样分型辨治慢性咽炎.《中医杂志》.2011,(第1期),第65页. * |
Also Published As
Publication number | Publication date |
---|---|
CN102091191A (en) | 2011-06-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102091191B (en) | Medicament for treating chronic pharyngitis | |
CN101129906B (en) | Orally taken traditional Chinese medicine composition for treating tuberculosis | |
CN101954062B (en) | Medicament for treating chronic pharyngitis | |
CN102145114B (en) | Novel traditional Chinese medicine for treating cold | |
CN103432374A (en) | Medicine for treating pneumonia of pig | |
CN103230549B (en) | Traditional Chinese medicine preparation for treating fever in children | |
CN103006872B (en) | Chinese medicinal preparation for treating flu | |
CN103495021B (en) | Traditional Chinese medicine for treating chronic pharyngitis | |
CN101036706A (en) | Wine for promoting blood circulation by removing blood stasis and for eliminating rheumatism | |
CN105327182A (en) | Medicine for treating child pertussis and preparation method thereof | |
CN106138637B (en) | Traditional Chinese medicine composition for promoting blood circulation, removing blood stasis, resisting rheumatism and relieving pain and preparation method thereof | |
CN103933343A (en) | Traditional Chinese medicine pill for treating bronchial asthma | |
CN103394064A (en) | Traditional Chinese medicine composition used for treating slight cold | |
CN101485844A (en) | Chinese medicinal composition for treating chronic gastritis | |
CN104524296A (en) | Traditional Chinese medicine composition for treating summerheat-heat stirring wind syndrome pattern summerheat convulsive disease | |
CN105362548A (en) | Traditional Chinese medicine for treating allergic asthma | |
CN105125716A (en) | Traditional Chinese medicinal preparation for treating upper respiratory infection | |
CN104971151A (en) | Traditional Chinese medicine for treating chronic pharyngitis | |
CN104998189A (en) | Traditional Chinese medicine powder for treating infantile oral ulcer of wind-heat spleen type and preparation method thereof | |
CN103356879A (en) | Traditional Chinese medicine formula for treating tetanus | |
CN104398778A (en) | Traditional Chinese medicine for treating pneumonia | |
CN117982576A (en) | Traditional Chinese medicine for treating cold and cough | |
CN103977313A (en) | Diuresis promoting and itching relieving pills and preparation method thereof | |
CN104399045A (en) | Medicament for treating hyperlipidemia | |
CN103494924A (en) | Chinese medicine composition for treating damp-heat stagnation acne |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Ma Rong Inventor after: Lu Zhengping Inventor before: Lu Zhengping |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: LU ZHENGPING TO: MA RONG LU ZHENGPING |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120620 Termination date: 20130221 |