CN111228355A - Traditional Chinese medicine composition for treating heart and lung diseases, preparation method thereof and clinical preparation - Google Patents
Traditional Chinese medicine composition for treating heart and lung diseases, preparation method thereof and clinical preparation Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a traditional Chinese medicine composition for treating heart and lung diseases, a preparation method thereof and a clinical preparation, wherein the traditional Chinese medicine composition for treating heart and lung diseases comprises the following components in parts by mass: 8-10 parts of ligusticum wallichii, 9-12 parts of poria cocos, 8-13 parts of divaricate saposhnikovia root, 7-10 parts of fructus aurantii, 8-11 parts of radix bupleuri, 10-15 parts of schizonepeta, 3-7 parts of liquorice and 7-12 parts of platycodon grandiflorum; through the compatibility of seven essences and the monarch and minister blessing chihuilide, the traditional Chinese medicine composition has the effects of relieving exterior syndrome with pungent and warm natured drugs, strengthening vital qi to eliminate pathogenic factors, warming and resolving cold phlegm, dredging air passages and filling nutrient and defensive qi, and achieves the purpose of radically treating heart and lung diseases.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating heart and lung diseases, a preparation method thereof and a clinical preparation for treating heart and lung diseases.
Background
With the continuous progress of science and technology, science and technology are integrated into the lives of people, and the science and technology changes the clothes and eating habits of people, particularly for food eaten by people, the technology specifically comprises the following steps: the technology is integrated with the variety improvement of raw materials, the cultivation of the raw materials and the processing of the raw materials, particularly in the cultivation process of the raw materials, due to the use of various advanced medicines, the medicine residues enable the medicine to easily enter human bodies at the top end of a food chain, and long-time accumulation causes the reduction of the immunocompetence of a human immune system, so that the human bodies are easily attacked by viruses or bacteria to cause cardiopulmonary diseases.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a traditional Chinese medicine composition for treating cardiopulmonary diseases.
The technical scheme adopted by the invention is as follows: a traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following components in parts by mass:
8-10 parts of ligusticum wallichii, 9-12 parts of poria cocos, 8-13 parts of divaricate saposhnikovia root, 7-10 parts of fructus aurantii, 8-11 parts of radix bupleuri, 10-15 parts of schizonepeta, 3-7 parts of liquorice and 7-12 parts of platycodon grandiflorum.
Further limited, the traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following components in parts by mass:
9 parts of ligusticum wallichii, 9 parts of poria cocos, 9 parts of divaricate saposhnikovia root, 9 parts of fructus aurantii, 9 parts of radix bupleuri, 12 parts of schizonepeta, 6 parts of liquorice and 9 parts of platycodon grandiflorum.
The invention has the beneficial effects that: through the compatibility of seven essences and the monarch and minister blessing chihuilide, the traditional Chinese medicine composition has the effects of relieving exterior syndrome with pungent and warm natured drugs, strengthening vital qi to eliminate pathogenic factors, warming and resolving cold phlegm, dredging air passages and filling nutrient and defensive qi, and achieves the purpose of radically treating heart and lung diseases.
The invention also provides a preparation method of the traditional Chinese medicine composition for treating cardiopulmonary diseases, which comprises the following steps:
taking 8-10 parts by mass of ligusticum wallichii, 9-12 parts by mass of poria cocos, 8-13 parts by mass of radix sileris, 7-10 parts by mass of fructus aurantii, 8-11 parts by mass of radix bupleuri, 10-15 parts by mass of schizonepeta, 3-7 parts by mass of liquorice and 7-12 parts by mass of platycodon grandiflorum, distilling with steam to collect volatile oil and distilled residual liquid to obtain medicine residues, adding water into the medicine residues, decocting, filtering, collecting filtrate, mixing the filtrate with the distilled residual liquid, and concentrating to obtain clear paste.
Further limiting, the number of times of steam distillation is 1-3, and each time lasts for 5-8 hours.
The invention has the beneficial effects that: the effective components in the components can overflow out as much as possible by a steam distillation method, so that the concentration of the components is kept in a certain range, and the synergistic effect can be achieved and the maximum synergistic effect can be achieved, thereby achieving the purpose of treating the cardiopulmonary diseases.
The invention also provides a clinical preparation for treating the cardiopulmonary diseases, which is prepared from the traditional Chinese medicine composition for treating the cardiopulmonary diseases and pharmaceutically acceptable auxiliary materials.
Further limited, the clinical preparation is granules, capsules, tablets, pills or oral liquid
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the embodiments of the present invention are described in detail and completely, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
Example 1
A traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following components in parts by mass:
8 parts of ligusticum wallichii, 10 parts of poria cocos, 8 parts of divaricate saposhnikovia root, 7 parts of fructus aurantii, 8 parts of radix bupleuri, 10 parts of schizonepeta, 3 parts of liquorice and 7 parts of platycodon grandiflorum.
Example 2
A traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following components in parts by mass:
9 parts of ligusticum wallichii, 9 parts of poria cocos, 9 parts of divaricate saposhnikovia root, 9 parts of fructus aurantii, 9 parts of radix bupleuri, 12 parts of schizonepeta, 6 parts of liquorice and 9 parts of platycodon grandiflorum.
Example 3
A traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following components in parts by mass:
10 parts of ligusticum wallichii, 12 parts of poria cocos, 13 parts of divaricate saposhnikovia root, 10 parts of fructus aurantii, 11 parts of radix bupleuri, 15 parts of schizonepeta, 7 parts of liquorice and 12 parts of platycodon grandiflorum.
Example 4
A preparation method of a traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following steps:
taking 9 parts by mass of ligusticum wallichii, 9 parts by mass of poria cocos, 9 parts by mass of radix sileris, 9 parts by mass of fructus aurantii, 9 parts by mass of radix bupleuri, 12 parts by mass of schizonepeta, 6 parts by mass of liquorice and 9 parts by mass of platycodon grandiflorum, performing steam distillation on the obtained volatile oil and the obtained distillation residue to obtain medicine residues, adding water into the obtained medicine residues, decocting the medicine residues, filtering the obtained decoction residues to obtain filtrate, mixing the filtrate with the distillation residue, and concentrating the obtained filtrate to obtain clear paste; wherein the number of steam distillations is 1 time, 8 hours each time.
Example 5
A preparation method of a traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following steps:
taking 8 parts by mass of ligusticum wallichii, 9 parts by mass of poria cocos, 8 parts by mass of radix sileris, 7 parts by mass of fructus aurantii, 8 parts by mass of radix bupleuri, 10 parts by mass of schizonepeta, 3 parts by mass of liquorice and 7 parts by mass of platycodon grandiflorum, performing steam distillation on the obtained volatile oil and the obtained distillation residue to obtain medicine residues, adding water into the obtained medicine residues, decocting the medicine residues, filtering the obtained decoction residues to obtain filtrate, mixing the filtrate with the distillation residue, and concentrating the obtained filtrate to obtain clear paste; wherein the number of steam distillations was 2 times, each for 6 hours.
Example 6
A preparation method of a traditional Chinese medicine composition for treating cardiopulmonary diseases comprises the following steps:
taking 10 parts by mass of ligusticum wallichii, 12 parts by mass of poria cocos, 13 parts by mass of radix sileris, 10 parts by mass of fructus aurantii, 11 parts by mass of radix bupleuri, 15 parts by mass of schizonepeta, 7 parts by mass of liquorice and 12 parts by mass of platycodon grandiflorum, performing steam distillation on the raw materials to collect volatile oil and distilled residual liquid to obtain medicine residues, adding water into the medicine residues, decocting the medicine residues, filtering the decoction, collecting filtrate, mixing the filtrate with the distilled residual liquid, and concentrating the mixture to obtain clear paste; wherein the number of steam distillations is 3 times, each for 5 hours.
Example 7
A clinical preparation for treating cardiopulmonary diseases comprises the following components in parts by weight;
8 parts of ligusticum wallichii, 10 parts of poria cocos, 8 parts of divaricate saposhnikovia root, 7 parts of fructus aurantii, 8 parts of radix bupleuri, 10 parts of schizonepeta, 3 parts of liquorice, 7 parts of platycodon grandiflorum, 2 parts of aspartame, 1.5 parts of orange essence, 2 parts of magnesium stearate and 3 parts of citric acid.
Example 8
A clinical preparation for treating cardiopulmonary diseases comprises the following components in parts by weight;
8 parts of ligusticum wallichii, 10 parts of poria cocos, 8 parts of divaricate saposhnikovia root, 7 parts of fructus aurantii, 8 parts of radix bupleuri, 10 parts of schizonepeta, 3 parts of liquorice, 7 parts of platycodon grandiflorum, 2 parts of aspartame, 1.5 parts of orange essence and 3 parts of citric acid; the clinical preparation is granules, capsules, tablets, pills or oral liquid.
Example 9
A clinical preparation for treating cardiopulmonary diseases comprises the following components in parts by weight;
8 parts of ligusticum wallichii, 10 parts of poria cocos, 8 parts of divaricate saposhnikovia root, 7 parts of fructus aurantii, 8 parts of radix bupleuri, 10 parts of schizonepeta, 3 parts of liquorice, 7 parts of platycodon grandiflorum, 2 parts of aspartame, 1.5 parts of orange essence, 2 parts of magnesium stearate and 3 parts of citric acid; the clinical preparation is tablets, and the weight of each tablet is 3 g.
Typical clinical cases
Cao Yi, woman, age 45, chest X , blood pressure, abnormal electrocardiogram; the clinical manifestations are as follows: no sweat, headache, limb joint pain, aversion to wind and severe cold, fever 37.6-39 ℃; stuffy nose, heavy voice, itching throat, thin and white sputum, preference for hot drinks or dry mouth, thin and white tongue and floating, rapid or tight pulse; etiology analysis: exterior-interior relation, interior cold and exterior heat, pathogenic wind-cold externally binding the exterior, defensive yang being depressed, cardiopulmonary blood circulation being obstructed, cold can be induced, respiratory airway phlegm obstruction or stasis obstruction, two points being identified as narrow, respiratory qi difficulty, chest stuffiness pain, easy vomiting, no sweating, lung skin and hair, lung not spreading, spleen descending and losing right, headache, heart, lung qi and blood deficiency, lusterless complexion, purple or white lips, limb pain, pneumococcus, sudden chill, throat itching or pain, body deficiency, exuberant yin cause, lesion, clinical watery nasal discharge, phlegm vomiting rarity, metabolism of lung and large intestine exterior-interior relation, cold secret or qi secret or rarefied, acid-base property being excessive; the tablets in example 9 were administered 3 times a day, 1 tablet at a time, and taken for 5 days, and the chest film was photographed again, and the blood pressure and the electrocardiogram were measured, and the results were improved; then, the patient continues to take the medicine for 5 days, the chest film is photographed again, the blood pressure and the electrocardiogram are measured, and the results of the electrocardiogram, the blood pressure and the chest film are normal.
The invention is not limited to the above alternative embodiments, and any other various forms of products can be obtained by anyone in the light of the present invention, but any changes in shape or structure thereof, which fall within the scope of the present invention as defined in the claims, fall within the scope of the present invention.
Claims (7)
1. A traditional Chinese medicine composition for treating cardiopulmonary diseases is characterized by comprising the following components in parts by mass:
8-10 parts of ligusticum wallichii, 9-12 parts of poria cocos, 8-13 parts of divaricate saposhnikovia root, 7-10 parts of fructus aurantii, 8-11 parts of radix bupleuri, 10-15 parts of schizonepeta, 3-7 parts of liquorice and 7-12 parts of platycodon grandiflorum.
2. The traditional Chinese medicine composition for treating cardiopulmonary diseases according to claim 1, which comprises the following components in parts by mass:
9 parts of ligusticum wallichii, 9 parts of poria cocos, 9 parts of divaricate saposhnikovia root, 9 parts of fructus aurantii, 9 parts of radix bupleuri, 12 parts of schizonepeta, 6 parts of liquorice and 9 parts of platycodon grandiflorum.
3. The method for preparing a Chinese medicinal composition for treating cardiopulmonary diseases according to claim 1 or 2, comprising the steps of:
taking 8-10 parts by mass of ligusticum wallichii, 9-12 parts by mass of poria cocos, 8-13 parts by mass of radix sileris, 7-10 parts by mass of fructus aurantii, 8-11 parts by mass of radix bupleuri, 10-15 parts by mass of schizonepeta, 3-7 parts by mass of liquorice and 7-12 parts by mass of platycodon grandiflorum, distilling with steam to collect volatile oil and distilled residual liquid to obtain medicine residues, adding water into the medicine residues, decocting, filtering, collecting filtrate, mixing the filtrate with the distilled residual liquid, and concentrating to obtain clear paste.
4. The method according to claim 3, wherein the steam distillation is performed 1 to 3 times for 5 to 8 hours.
5. The Chinese medicinal composition prepared by the preparation method of claim 3 or 4.
6. A clinical preparation for treating cardiopulmonary diseases, which comprises the Chinese medicinal composition of claim 1, claim 2 or claim 5 and pharmaceutically acceptable adjuvants.
7. The clinical preparation according to claim 6, wherein the clinical preparation is granules, capsules, tablets, pills or oral liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010198320.8A CN111228355A (en) | 2020-03-19 | 2020-03-19 | Traditional Chinese medicine composition for treating heart and lung diseases, preparation method thereof and clinical preparation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115531455A (en) * | 2021-06-29 | 2022-12-30 | 山东新时代药业有限公司 | Application of traditional Chinese medicine composition in preparation of medicine for treating hypokalemia |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412676A (en) * | 2015-12-31 | 2016-03-23 | 闫冷 | Medicine for treating meat pigeon wind-heat cold and preparation method therefor |
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2020
- 2020-03-19 CN CN202010198320.8A patent/CN111228355A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412676A (en) * | 2015-12-31 | 2016-03-23 | 闫冷 | Medicine for treating meat pigeon wind-heat cold and preparation method therefor |
Non-Patent Citations (1)
| Title |
|---|
| 李瑞泉: "介绍防治流行性感冒的有效方", 《中国临床医生》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115531455A (en) * | 2021-06-29 | 2022-12-30 | 山东新时代药业有限公司 | Application of traditional Chinese medicine composition in preparation of medicine for treating hypokalemia |
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Application publication date: 20200605 |