CN111035688A - Preparation method of three-powder traditional Chinese medicine swelling agent - Google Patents
Preparation method of three-powder traditional Chinese medicine swelling agent Download PDFInfo
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- CN111035688A CN111035688A CN201910250641.5A CN201910250641A CN111035688A CN 111035688 A CN111035688 A CN 111035688A CN 201910250641 A CN201910250641 A CN 201910250641A CN 111035688 A CN111035688 A CN 111035688A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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Abstract
The invention discloses a preparation method of a three-powder traditional Chinese medicine swelling agent, relates to the technical field of traditional Chinese medicines, and mainly aims to solve the problems of low utilization rate of traditional Chinese medicine products, poor treatment effect and no elimination of toxic and side effects caused by the existing process; the preparation method of the three-powder traditional Chinese medicine swelling agent comprises the following steps: the preparation method comprises the steps of selecting and selecting the traditional Chinese medicine raw materials, chopping and carrying out superfine grinding, extracting the residue, adding the mixture, carrying out fermentation treatment, carrying out puffing granulation, drying, subpackaging and packaging, improving the utilization rate of the effective components of the traditional Chinese medicine product, improving the treatment effect, and eliminating the toxic and side effects of the traditional Chinese medicine raw materials through fermentation treatment.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a preparation method of a three-powder traditional Chinese medicine swelling agent.
Background
The three-powder traditional Chinese medicine swelling agent refers to a medicine for treating the rheum officinale, the radix scutellariae, the phellodendron amurense and the folium isatidis for aquatic fishes, has a good treatment effect on bacterial fish rancidity, rotten gills and enteritis of the aquatic fishes, belongs to powder of Chinese veterinary pharmacopoeia, is fed by mixing bait in the using process, causes a large amount of medicine loss due to the influence of conditions and using methods, and belongs to an oral medicine, so that the final medicine which can be foraged by the fishes is less than 20% of the product according to estimation.
The existing traditional Chinese medicine puffed product mainly has the following problems: (1) most of the traditional Chinese medicines belong to wood structures, have high fiber content, and have a large amount of coarse fibers after being subjected to superfine grinding and sieving, so that the traditional Chinese medicines cannot be fully utilized, and the active ingredients of the traditional Chinese medicines are reduced; (2) the traditional Chinese medicine product is not fermented, the toxic and side effects of the traditional Chinese medicine cannot be correspondingly eliminated, and the treatment effect of the traditional Chinese medicine cannot be maximized. The product solves the existing problems by changing the existing processing technology according to market information feedback and company test example conclusions.
Disclosure of Invention
The invention aims to provide a preparation method of a three-powder traditional Chinese medicine swelling agent, which improves the utilization rate of traditional Chinese medicine and improves the treatment effect.
In order to achieve the purpose, the invention provides the following technical scheme:
a preparation method of a three-powder traditional Chinese medicine swelling agent comprises the following steps:
step 1: the traditional Chinese medicine raw material mixture is picked and selected, the traditional Chinese medicine raw material mixture is cleaned in the picking and selecting process, redundant impurities are removed, and the traditional Chinese medicine raw material mixture with highest quality and best appearance is selected for standby application, so that the effect of the prepared traditional Chinese medicine can be improved;
step 2: crushing the standby traditional Chinese medicine raw material mixture in a crusher to obtain traditional Chinese medicine powder, sieving the residue of the traditional Chinese medicine powder to obtain traditional Chinese medicine powder I and traditional Chinese medicine powder II respectively, wherein the traditional Chinese medicine powder II is residue powder, and adding drinking water and an extracting solution into the traditional Chinese medicine powder II for decoction to obtain residue extracting solution;
and step 3: mixing the traditional Chinese medicine powder I and the residue extracting solution, adding the extracting solution into the mixture, fully and uniformly stirring the extracting solution to obtain a traditional Chinese medicine mixed solution, decocting the traditional Chinese medicine mixed solution again, and fermenting the traditional Chinese medicine mixed solution;
and 4, step 4: putting the fermented traditional Chinese medicine into equipment for puffing and granulating to obtain traditional Chinese medicine granules, and drying the traditional Chinese medicine granules;
and 5: and finally, subpackaging the dried traditional Chinese medicine granules firstly and then putting the granules into a packaging machine for packaging.
On the basis of the technical scheme, the invention also provides the following optional technical scheme:
a preparation method of a three-powder traditional Chinese medicine swelling agent comprises the following steps:
step 1: the traditional Chinese medicine raw material mixture is picked and selected, the traditional Chinese medicine raw material mixture is cleaned in the picking and selecting process, redundant impurities are removed, and the traditional Chinese medicine raw material mixture with highest quality and best appearance is selected for standby application, so that the effect of the prepared traditional Chinese medicine can be improved;
step 2: putting the standby traditional Chinese medicine raw material mixture into a grinder for grinding to obtain traditional Chinese medicine powder;
and step 3: adding the extracting solution into the traditional Chinese medicine powder, fully and uniformly stirring to obtain a traditional Chinese medicine mixed solution, and then performing fermentation treatment on the traditional Chinese medicine mixed solution;
and 4, step 4: putting the fermented traditional Chinese medicine into equipment for puffing and granulating to obtain traditional Chinese medicine granules, and drying the traditional Chinese medicine granules;
and 5: and finally, subpackaging the dried traditional Chinese medicine granules firstly and then putting the granules into a packaging machine for packaging.
In one alternative: the extracting solution is an ethanol solution.
In one alternative: the pulverization includes chopping and superfine pulverization.
In one alternative: the pulverizer is a superfine pulverizer.
In one alternative: the equipment used for puffing and granulating is a puffing machine.
In one alternative: the traditional Chinese medicine particles are placed in the packaging bag.
In one alternative: the Chinese medicinal materials include radix et rhizoma Rhei, Scutellariae radix, cortex Phellodendri and folium Isatidis.
Compared with the prior art, the invention has the following beneficial effects:
1. the traditional Chinese medicine product is subjected to superfine grinding, then the residue is sieved, and the effective components are retained to the maximum extent through secondary decoction and alcohol extraction, so that the maximum utilization rate of the traditional Chinese medicine product is ensured;
2. through traditional Chinese medicine fermentation treatment, toxic and side effects are eliminated, the property of the traditional Chinese medicine is changed, and the efficacy of the traditional Chinese medicine product is maximized.
Detailed Description
The examples are given solely for the purpose of illustration and are not intended to limit the scope of the invention. Any obvious modifications or variations can be made to the present invention without departing from the spirit or scope of the present invention.
Example 1
In the embodiment of the invention, a preparation method of a three-powder traditional Chinese medicine swelling agent comprises the following steps:
step 1: the traditional Chinese medicine raw material mixture is picked and selected, the traditional Chinese medicine raw material mixture is cleaned in the picking and selecting process, redundant impurities are removed, and the traditional Chinese medicine raw material mixture with highest quality and best appearance is selected for standby application, so that the effect of the prepared traditional Chinese medicine can be improved;
step 2: cutting the mixture of the raw materials into pieces, and pulverizing in a superfine pulverizer to obtain Chinese medicinal powder;
and step 3: adding the extracting solution into the traditional Chinese medicine powder, fully and uniformly stirring to obtain a traditional Chinese medicine mixed solution, adding the extracting solution into the traditional Chinese medicine powder, decocting to effectively remove wood fibers in the traditional Chinese medicine, fully utilizing the effective components of the traditional Chinese medicine, and performing fermentation treatment on the traditional Chinese medicine mixed solution to eliminate toxic and side effects contained in the traditional Chinese medicine mixed solution to obtain the maximum treatment effect;
and 4, step 4: the fermented traditional Chinese medicine is put into a bulking machine for bulking and granulating to obtain traditional Chinese medicine granules, and then the traditional Chinese medicine granules are dried to remove water in the traditional Chinese medicine granules, so that the traditional Chinese medicine granules are convenient to store and can be stored for a longer time;
and 5: and finally, subpackaging the dried traditional Chinese medicine particles firstly and then putting the traditional Chinese medicine particles into a packaging machine for packaging, wherein the traditional Chinese medicine particles are placed in a packaging bag.
Preferably, the extraction solution is an ethanol solution.
Preferably, the Chinese medicinal raw materials include rhubarb, scutellaria, phellodendron and isatis leaf.
Example 2
In the embodiment of the invention, a preparation method of a three-powder traditional Chinese medicine swelling agent comprises the following steps:
step 1: the traditional Chinese medicine raw material mixture is picked and selected, the traditional Chinese medicine raw material mixture is cleaned in the picking and selecting process, redundant impurities are removed, and the traditional Chinese medicine raw material mixture with highest quality and best appearance is selected for standby application, so that the effect of the prepared traditional Chinese medicine can be improved;
step 2: cutting the standby traditional Chinese medicine raw material mixture, then putting the cut mixture into an ultrafine grinder for grinding to obtain traditional Chinese medicine powder, then sieving the residue of the traditional Chinese medicine powder to respectively obtain traditional Chinese medicine powder I and traditional Chinese medicine powder II, wherein the traditional Chinese medicine powder II is residue powder, and adding drinking water and an extracting solution into the traditional Chinese medicine powder II for decoction to obtain residue extracting solution;
and step 3: mixing the traditional Chinese medicine powder I and the residue extracting solution, adding the extracting solution into the traditional Chinese medicine powder I and the residue extracting solution, fully and uniformly stirring to obtain a traditional Chinese medicine mixed solution, decocting again, adding the extracting solution into the traditional Chinese medicine powder I and the residue extracting solution, decocting, effectively removing wood fibers in traditional Chinese medicines, fully utilizing effective components of the traditional Chinese medicines, fermenting the traditional Chinese medicine mixed solution, eliminating toxic and side effects contained in the traditional Chinese medicine mixed solution, and obtaining the maximum treatment effect;
and 4, step 4: the fermented traditional Chinese medicine is put into a bulking machine for bulking and granulating to obtain traditional Chinese medicine granules, and then the traditional Chinese medicine granules are dried to remove water in the traditional Chinese medicine granules, so that the traditional Chinese medicine granules are convenient to store and can be stored for a longer time;
and 5: and finally, subpackaging the dried traditional Chinese medicine particles firstly and then putting the traditional Chinese medicine particles into a packaging machine for packaging, wherein the traditional Chinese medicine particles are placed in a packaging bag.
Preferably, the extraction solution is an ethanol solution.
Preferably, the Chinese medicinal raw materials include rhubarb, scutellaria, phellodendron and isatis leaf.
The working principle of the invention is as follows: the Chinese medicinal composition is prepared by micronizing, extracting with alcohol, removing wood fiber, and fermenting to remove toxic and side effects and improve therapeutic effect.
The above description is only for the specific embodiments of the present disclosure, but the scope of the present disclosure is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present disclosure, and all the changes or substitutions should be covered within the scope of the present disclosure. Therefore, the protection scope of the present disclosure shall be subject to the protection scope of the claims.
Claims (8)
1. A preparation method of a three-powder traditional Chinese medicine swelling agent is characterized by comprising the following steps:
step 1: picking and selecting the traditional Chinese medicine raw material mixture, cleaning the traditional Chinese medicine raw material mixture in the picking and selecting process, removing redundant impurities, and selecting the traditional Chinese medicine raw material mixture with highest quality and best appearance for later use;
step 2: crushing the standby traditional Chinese medicine raw material mixture in a crusher to obtain traditional Chinese medicine powder, sieving the residue of the traditional Chinese medicine powder to obtain traditional Chinese medicine powder I and traditional Chinese medicine powder II respectively, wherein the traditional Chinese medicine powder II is residue powder, and adding drinking water and an extracting solution into the traditional Chinese medicine powder II for decoction to obtain residue extracting solution;
and step 3: mixing the traditional Chinese medicine powder I and the residue extracting solution, adding the extracting solution into the mixture, fully and uniformly stirring the extracting solution to obtain a traditional Chinese medicine mixed solution, decocting the traditional Chinese medicine mixed solution again, and fermenting the traditional Chinese medicine mixed solution;
and 4, step 4: putting the fermented traditional Chinese medicine into equipment for puffing and granulating to obtain traditional Chinese medicine granules, and drying the traditional Chinese medicine granules to remove water in the traditional Chinese medicine granules;
and 5: and finally, subpackaging the dried traditional Chinese medicine granules firstly and then putting the granules into a packaging machine for packaging.
2. A preparation method of a three-powder traditional Chinese medicine swelling agent is characterized by comprising the following steps:
step 1: the traditional Chinese medicine raw material mixture is picked and selected, the traditional Chinese medicine raw material mixture is cleaned in the picking and selecting process, redundant impurities are removed, and the traditional Chinese medicine raw material mixture with highest quality and best appearance is selected for standby application, so that the effect of the prepared traditional Chinese medicine can be improved;
step 2: putting the standby traditional Chinese medicine raw material mixture into a grinder for grinding to obtain traditional Chinese medicine powder;
and step 3: adding the extracting solution into the traditional Chinese medicine powder, fully and uniformly stirring to obtain a traditional Chinese medicine mixed solution, and then performing fermentation treatment on the traditional Chinese medicine mixed solution;
and 4, step 4: putting the fermented traditional Chinese medicine into equipment for puffing and granulating to obtain traditional Chinese medicine granules, and drying the traditional Chinese medicine granules to remove water in the traditional Chinese medicine granules;
and 5: and finally, subpackaging the dried traditional Chinese medicine granules firstly and then putting the granules into a packaging machine for packaging.
3. The method for preparing a three-powder traditional Chinese medicine swelling agent according to claim 1 or 2, wherein the extracting solution is an ethanol solution.
4. The method for preparing a three-powder traditional Chinese medicine swelling agent according to claim 1 or 2, wherein the pulverization comprises chopping and ultrafine pulverization.
5. The method for preparing a three-powder traditional Chinese medicine swelling agent as claimed in claim 1 or 2, wherein the pulverizer is an ultrafine pulverizer.
6. The method for preparing a three-powder traditional Chinese medicine puffing agent according to claim 1 or 2, wherein the equipment used for puffing and granulating is a puffing machine.
7. The preparation method of the three-powder traditional Chinese medicine swelling agent according to claim 1 or 2, wherein the traditional Chinese medicine particles are placed in a packaging bag.
8. The preparation method of a three-powder traditional Chinese medicine swelling agent as claimed in claim 1 or 2, wherein the traditional Chinese medicine raw materials comprise rhubarb, radix scutellariae, phellodendron bark and folium isatidis.
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CN201910250641.5A CN111035688A (en) | 2019-03-29 | 2019-03-29 | Preparation method of three-powder traditional Chinese medicine swelling agent |
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CN201910250641.5A CN111035688A (en) | 2019-03-29 | 2019-03-29 | Preparation method of three-powder traditional Chinese medicine swelling agent |
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Application publication date: 20200421 |
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RJ01 | Rejection of invention patent application after publication |