CN110487618A - A kind of band shakes up the Sample Dilution device of function - Google Patents

A kind of band shakes up the Sample Dilution device of function Download PDF

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Publication number
CN110487618A
CN110487618A CN201910858308.2A CN201910858308A CN110487618A CN 110487618 A CN110487618 A CN 110487618A CN 201910858308 A CN201910858308 A CN 201910858308A CN 110487618 A CN110487618 A CN 110487618A
Authority
CN
China
Prior art keywords
diluted cup
shakes
function
dilution
diluted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201910858308.2A
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Chinese (zh)
Other versions
CN110487618B (en
Inventor
苗新利
汪治鑫
宋坤
程思奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Hybiome Biomedical Engineering Co Ltd
Original Assignee
Suzhou Hybiome Biomedical Engineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Suzhou Hybiome Biomedical Engineering Co Ltd filed Critical Suzhou Hybiome Biomedical Engineering Co Ltd
Priority to CN201910858308.2A priority Critical patent/CN110487618B/en
Priority to PCT/CN2019/111371 priority patent/WO2021046961A1/en
Publication of CN110487618A publication Critical patent/CN110487618A/en
Application granted granted Critical
Publication of CN110487618B publication Critical patent/CN110487618B/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/093Cleaning containers, e.g. tanks by the force of jets or sprays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • G01N2001/386Other diluting or mixing processes

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

This application involves the Sample Dilution devices that a kind of band shakes up function, dilute position when diluted cup opening straight up, straight down, injection needle protrudes into diluted cup the opening of diluted cup from top when positioned at dilution position when cleaning positions, successively will be in reagent and dilution injection diluted cup.After having infused liquid, again by shaking up Component driver diluted cup along its axial movement or swinging to realize and shake up liquid in the in-plane direction, the liquid shaken up is siphoned away by aspirating needle again, then diluted cup rotates to cleaning positions, and cleaning needle extend into blowing cleaning solution in diluted cup and cleans to diluted cup.Therefore, band of the invention shakes up the Sample Dilution device of function while having the function of shaking up and Sample Dilution.

Description

A kind of band shakes up the Sample Dilution device of function
Technical field
The application belongs to the field of medical instrument technology, and the Sample Dilution device of function is shaken up more particularly, to a kind of band.
Background technique
In chemiluminescence immunoassay detection, it is low that demand of each detection project to sample labeling object concentration has height to have.And entirely certainly It is very necessary that dynamic chemiluminescent analyzer device is equipped with a set of Sample Dilution mechanism.
Full-automatic chemiluminescence analysis instrument at present, when handling Sample Dilution project, using two ways: consumption one Reaction cup, as cut-back tank;Or using the repeatable dilution mechanism for rinsing the diluted cup used of configuration.
Chinese patent literature CN108458915A discloses a kind of dual cavity dilution device, comprising: cleaning chamber, dilution are held Device, cleaning pipe and fluid injection chamber;The top and bottom side wall of the cleaning chamber is respectively equipped with filling opening, liquid outlet;The dilution Container is rotatably dispose in cleaning chamber, and two dilution chambers open at one end are symmetrically arranged on the cut-back tank, described dilute Releasing container being rotated by driving equipment;The fluid injection chamber is set to cleaning chamber in the following, and fluid injection chamber connection There is liquid injection pipe;The cleaning pipe protrudes into cleaning chamber across fluid injection chamber and by the intercommunicating pore fluid injection chamber and cleaning chamber It is interior, and can be moved up and down under the driving of driving equipment.Dual cavity dilution device provided by the invention, avoids in cleaning chamber Phosphate flows into fluid injection chamber, while being rinsed to cleaning pipe.However above-mentioned dual cavity dilution device can not be shaken up Operation.
Summary of the invention
The technical problem to be solved by the present invention is to solve deficiency in the prior art, so that providing one kind can be simultaneously With the Sample Dilution device shaken up with Sample Dilution function.
The technical solution adopted by the present invention to solve the technical problems is:
A kind of band shakes up the Sample Dilution device of function, comprising:
Dilution component shakes up component and cleaning assembly;
Dilute component include dilution rotary drive, with interior accommodating space can be in dilution rotary drive Driving under along vertical plane rotation diluted cup fixed frame, the diluted cup in accommodation space is set, and the diluted cup passes through soft Property fixed form be arranged in the diluted cup fixed frame, the diluted cup fixed frame can reach under the driving of rotary drive Dilute position and cleaning positions;
Shaking up component includes shaking up actuator, is protruded into accommodation space from the virtual pivot of the diluted cup fixed frame Disturbing rod, the actuator that shakes up can drive disturbing rod to be axially moved along it or in the in-plane direction swing, and disturb The bottom of the diluted cup is so that the diluted cup shakes;
The cleaning assembly includes lifting actuator, the cleaning needle moved by the lifting actuator driving, described clear Wash needle can extend into the diluted cup positioned at cleaning positions under the drive of the lifting actuator.
Preferably, band of the invention shakes up the Sample Dilution device of function, and the diluted cup is two, two diluted cup phases To setting.
Preferably, band of the invention shakes up the Sample Dilution device of function, and the diluted cup fixed mount setting is in dilution chamber It is interior, opening is provided at the top and bottom of the dilution chamber, the component that shakes up is arranged in the dilution chamber.
Preferably, band of the invention shakes up the Sample Dilution device of function, and the dilution chamber bottom is provided with cleaning solution appearance Receive chamber, the opening of cleaning solution accommodating chamber bottom is provided with seal assembly, and the cleaning needle can pass through seal assembly, described Cleaning solution accommodating chamber is extend into diluted cup.
Preferably, band of the invention shakes up the Sample Dilution device of function, has flange flexible at the top of the diluted cup, The diluted cup is fixed on the diluted cup fixed frame by the flange.
Preferably, band of the invention shakes up the Sample Dilution device of function, and the disturbing rod end is provided with slide block, institute It states diluted cup bottom and is provided with holding tank for accommodating the slide block, the slide block can drive the dilution when moving Cup movement is swung.
Preferably, band of the invention shakes up the Sample Dilution device of function, and the lifting actuator passes through vertical direction cloth The linear slider sliding track mechanism driving catheter-fixing rack movement set, the cleaning needle are fixed on the catheter-fixing rack.
Preferably, band of the invention shakes up the Sample Dilution device of function, and the rotary drive includes rotating electric machine, with The belt pulley of the rotation axis connection of diluted cup fixed frame, rotating electric machine are connect by synchronous belt with belt pulley.
Preferably, band of the invention shakes up the Sample Dilution device of function, offers form in the dilution chamber.
Preferably, band of the invention shakes up the Sample Dilution device of function, it is described shake up actuator by cam mechanism with The disturbing rod connection.
The beneficial effects of the present invention are:
Band of the invention shakes up the Sample Dilution device of function, and the opening of diluted cup straight up, is cleaned when diluting position Straight down, injection needle protrudes into diluted cup the opening of diluted cup from top when positioned at dilution position, successively by reagent when position In dilution injection diluted cup.After having infused liquid, then by shaking up Component driver diluted cup along its axial movement or flat Face side is swung up to realize and shake up to liquid, and the liquid shaken up is siphoned away by aspirating needle again, and then diluted cup rotates To cleaning positions, cleaning needle extend into blowing cleaning solution in diluted cup and cleans to diluted cup.Therefore, band of the invention shakes up The Sample Dilution device of function has the function of shaking up simultaneously and Sample Dilution.
Detailed description of the invention
The technical solution of the application is further illustrated with reference to the accompanying drawings and examples.
Fig. 1 is the structural schematic diagram that the band of the embodiment of the present application shakes up the Sample Dilution device of function;
Fig. 2 a is the structural schematic diagram of the dilution component of the embodiment of the present application;
Fig. 2 b is the cross-sectional view of the dilution component of the embodiment of the present application;
Fig. 3 is the dilution chamber of the embodiment of the present application and the cross-sectional view of diluted cup;
Fig. 4 be the embodiment of the present application dilution chamber and diluted cup with shake up the cross-sectional view of component;
Fig. 5 is the cross-sectional view that the band of the embodiment of the present application shakes up the Sample Dilution device of function;
Appended drawing reference in figure are as follows:
100 dilution components
111 dilution chamber
112 forms
113 cleaning solution accommodating chambers
121 belt pulleys
122 rotary shafts
123 diluted cup fixed frames
124 diluted cups
125 flanges
126 bearing groups
131 rotary drives
132 synchronous belts
200 shake up component
201 shake up actuator;
202 motor fixing frames;
203 cam mechanisms;
204 disturbing rods;
205 slide blocks;
300 cleaning assemblies;
301 lifting actuators;
302 chassis;
303 linear slider sliding track mechanisms;
304 catheter-fixing racks;
305 cleaning needles;
306 seal assemblies.
Specific embodiment
It should be noted that in the absence of conflict, the features in the embodiments and the embodiments of the present application can phase Mutually combination.
In the description of the present application, it is to be understood that term " center ", " longitudinal direction ", " transverse direction ", "upper", "lower", The orientation or positional relationship of the instructions such as "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description the application and simplifies description, rather than instruction or dark Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair The limitation of the application protection scope.In addition, term " first ", " second " etc. are used for description purposes only, and should not be understood as indicating Or it implies relative importance or implicitly indicates the quantity of indicated technical characteristic." first ", " second " etc. are defined as a result, Feature can explicitly or implicitly include one or more of the features.In the description of the invention, unless separately It is described, the meaning of " plurality " is two or more.
In the description of the present application, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can To be mechanical connection, it is also possible to be electrically connected;It can be directly connected, can also can be indirectly connected through an intermediary Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood by concrete condition Concrete meaning in this application.
It is described in detail the technical solution of the application below with reference to the accompanying drawings and in conjunction with the embodiments.
Embodiment
The present embodiment provides the Sample Dilution devices that a kind of band shakes up function, as shown in Figure 1, comprising:
Dilution component 100 shakes up component 200 and cleaning assembly 300;
Diluting component 100, with rotary drive 131, (rotary drive 131 includes rotating electric machine, with diluted cup including dilution The belt pulley 121 that the rotary shaft 122 of fixed frame 123 connects, rotating electric machine are connect by synchronous belt 132 with belt pulley 121), tool There is the diluted cup fixed frame that can be rotated under the driving of dilution rotary drive 131 along vertical plane of interior accommodating space 123, the diluted cup 124 in accommodation space is set, and the diluted cup 124 passes through flexible fixed form and is arranged in the diluted cup Fixed frame 123, the diluted cup fixed frame 123 can reach dilution position and cleaning position under the driving of rotary drive 131 It sets;The dilution is motor, hydraulic cylinder, cylinder etc. with rotary drive
Shaking up component 200 includes shaking up actuator 201, is protruded into from the virtual pivot of the diluted cup fixed frame 123 Disturbing rod 204 in accommodation space, the actuator 201 that shakes up can drive disturbing rod 204 to be axially moved or swing along it, And the bottom of the diluted cup 124 is disturbed so that the diluted cup 124 shakes;
The cleaning assembly 300 includes lifting actuator 301, the cleaning moved by lifting actuator 301 driving Needle 305, the cleaning needle 305 can extend into the rotation angle positioned at cleaning positions under the drive of the lifting actuator 301 In the diluted cup 124 of degree.
The band of above-described embodiment shakes up the Sample Dilution device of function, when diluting position the opening of diluted cup 124 vertically to On, straight down, injection needle protrudes into diluted cup 124 from top to the opening of diluted cup 124 when positioned at dilution position when cleaning positions It is interior, it successively will be in reagent and dilution injection diluted cup 124.After having infused liquid, then by shaking up the driving diluted cup of component 200 124 are axially moved along it or swing in the in-plane direction to realize and shake up to liquid, and the liquid shaken up passes through suction again Liquid needle siphons away, and then diluted cup 124 rotates to cleaning positions, and cleaning needle 305, which is extend into diluted cup 124, is blown cleaning solution pair Diluted cup 124 is cleaned.Therefore, the band of the present embodiment shake up the Sample Dilution device of function while having shake up it is dilute with sample The function of releasing.
The diluted cup fixed frame 123 is arranged in dilution chamber 111, and the top and bottom of the dilution chamber 111 are respectively provided with There is opening, the component 200 that shakes up is arranged in the dilution chamber 111.Form can be opened up in dilution chamber 111 for convenience of observing 112。
As an improvement embodiment, 111 bottom of dilution chamber is provided with cleaning solution accommodating chamber 113, described clear The opening of 113 bottom of washing lotion accommodating chamber is provided with seal assembly 306, and the cleaning needle 305 can pass through seal assembly 306, institute Cleaning solution accommodating chamber 113 is stated to extend into diluted cup 124.Cleaning solution accommodating chamber 113 has cleaning solution tap, seal assembly 306 can prevent cleaning solution from flowing away from the gap location of inner wall and cleaning needle 305.
Further, there is flange 125 flexible, the diluted cup 124 passes through the flange at the top of the diluted cup 124 125 are fixed on the diluted cup fixed frame 123, for example the diluted cup fixed frame can be fixed on by screw or rivet On 123.As improved implementation method, the diluted cup 124 can be fixed by spring and the diluted cup fixed frame 123, To guarantee that there is the freedom degree that can be shaken or swing.Rotary shaft 122 is supported by bearing 126 is fixed.
Further, 204 end of disturbing rod is provided with circular slide block 205,124 bottom of the diluted cup setting There is the holding tank for accommodating the slide block 205, the slide block 205 can drive the diluted cup 124 to move when moving Or it swings.
Further, the actuator 201 that shakes up is connect by cam mechanism 203 with the disturbing rod 204.
Further, the lifting actuator 301 is led by linear slider sliding track mechanism 303 arranged in a vertical direction driving Tube fixing device 304 moves, and the cleaning needle 305 is fixed on the catheter-fixing rack 304, transports together with the cleaning needle 305 It is dynamic.
Further, the diluted cup 124 is two, and two diluted cups are oppositely arranged, and two diluted cups 124 can make clearly It washes and dilutes while carrying out with fluid injection, to improve equipment service efficiency.
Chassis 302 is for installing above-mentioned all components.
It is enlightenment with the above-mentioned desirable embodiment according to the application, through the above description, relevant staff is complete Full various changes and amendments can be carried out in the range of without departing from this item application technical idea.The technology of this item application Property range is not limited to the contents of the specification, it is necessary to which the technical scope thereof is determined according to the scope of the claim.

Claims (10)

1. the Sample Dilution device that a kind of band shakes up function characterized by comprising
Dilution component (100) shakes up component (200) and cleaning assembly (300);
Diluting component (100) includes dilution rotary drive, and can use in dilution with interior accommodating space rotates driving Along the diluted cup fixed frame (123) of vertical plane rotation under the driving of part (131), the diluted cup (124) in accommodation space is set, The diluted cup (124) passes through flexible fixed form and is arranged in the diluted cup fixed frame (123), the diluted cup fixed frame (123) dilution position and cleaning positions can be reached under the driving of rotary drive (131);
Shaking up component (200) includes shaking up actuator (201), is stretched from the virtual pivot of the diluted cup fixed frame (123) Enter the disturbing rod (204) in accommodation space, the actuator (201) that shakes up can drive disturbing rod (204) along its axial movement Or it swings in the in-plane direction, and disturb the bottom of the diluted cup (124) so that the diluted cup (124) shakes;
The cleaning assembly (300) includes lifting actuator (301), is moved clear by lifting actuator (301) driving It washes needle (305), the cleaning needle (305) can extend under the drive of lifting actuator (301) is located at cleaning positions The diluted cup (124) in.
2. the Sample Dilution device that band according to claim 1 shakes up function, which is characterized in that the diluted cup (124) It is two, two diluted cups are oppositely arranged.
3. the Sample Dilution device that band according to claim 1 shakes up function, which is characterized in that the diluted cup fixed frame (123) setting is provided with opening at the top and bottom of the dilution chamber (111) in dilution chamber (111), described to shake up component (200) it is arranged on the dilution chamber (111).
4. the Sample Dilution device that band according to claim 3 shakes up function, which is characterized in that the dilution chamber (111) Bottom is provided with cleaning solution accommodating chamber (113), and the opening of cleaning solution accommodating chamber (113) bottom is provided with seal assembly (306), the cleaning needle (305) can pass through seal assembly (306), the cleaning solution accommodating chamber (113) extend into diluted cup (124) in.
5. the Sample Dilution device that band according to claim 1 shakes up function, which is characterized in that the diluted cup (124) Top has flange flexible (125), and the diluted cup (124) is fixed on the diluted cup by the flange (125) and fixes On frame (123).
6. the Sample Dilution device that band according to claim 1 shakes up function, which is characterized in that the disturbing rod (204) End is provided with slide block (205), and diluted cup (124) bottom is provided with the receiving for accommodating the slide block (205) Slot, the slide block (205) can drive the diluted cup (124) to move or swing when moving.
7. the Sample Dilution device that band according to claim 1 shakes up function, which is characterized in that the lifting actuator (301) pass through linear slider sliding track mechanism (303) arranged in a vertical direction driving catheter-fixing rack (304) movement, the cleaning Needle (305) is fixed on the catheter-fixing rack (304).
8. the Sample Dilution device that band according to claim 1-7 shakes up function, which is characterized in that the rotation Actuator (131) includes rotating electric machine, the belt pulley (121) with the rotation axis connection of diluted cup fixed frame (123), rotating electric machine It is connect by synchronous belt (132) with belt pulley (121).
9. the Sample Dilution device that band according to claim 3 shakes up function, which is characterized in that the dilution chamber (111) On offer form (112).
10. -9 described in any item bands shake up the Sample Dilution device of function according to claim 1, which is characterized in that described to shake Even actuator (201) is connect by cam mechanism (203) with the disturbing rod (204).
CN201910858308.2A 2019-09-11 2019-09-11 Area shakes even sample diluting device of function Active CN110487618B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201910858308.2A CN110487618B (en) 2019-09-11 2019-09-11 Area shakes even sample diluting device of function
PCT/CN2019/111371 WO2021046961A1 (en) 2019-09-11 2019-10-16 Sample dilution device having shaking up function

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910858308.2A CN110487618B (en) 2019-09-11 2019-09-11 Area shakes even sample diluting device of function

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CN110487618A true CN110487618A (en) 2019-11-22
CN110487618B CN110487618B (en) 2021-03-02

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WO (1) WO2021046961A1 (en)

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