CN110338280A - A kind of medicinal fish feed that can reduce antibiotic residue - Google Patents
A kind of medicinal fish feed that can reduce antibiotic residue Download PDFInfo
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- CN110338280A CN110338280A CN201910617877.8A CN201910617877A CN110338280A CN 110338280 A CN110338280 A CN 110338280A CN 201910617877 A CN201910617877 A CN 201910617877A CN 110338280 A CN110338280 A CN 110338280A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
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- A23K20/22—Compounds of alkali metals
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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Abstract
The present invention provides a kind of medicinal fish feeds, including A agent and B agent, A agent includes bait, amino acid complex, vitamin C and terramycin, B agent includes bait, amino acid complex, acetic acid, hydrogen peroxide and potassium ferrate, the bait contained in A agent and B agent, the amount of amino acid complex is equal, contain bait in A agent, the amino acid complex of 1-2 parts by weight, the terramycin of the vitamin C of 0.1-0.5 parts by weight and 1 parts by weight, contain bait in B agent, the amino acid complex of 1-2 parts by weight, the acetic acid of 0.1-0.5 parts by weight, the hydrogen peroxide of 1-5 parts by weight and the potassium ferrate of 2-8 parts by weight.Medicinal fish feed of the invention can significantly reduce fish only intracorporal Determination of oxytetracycline residues, so as to which off-drug period of the terramycin drug when being applied to aquaculture is greatly reduced.
Description
Technical field
The invention belongs to Medicines in Aquaculture, and in particular to one kind can reduce the medicinal fish feed of antibiotic residue.
Background technique
Terramycin is widely used in aquaculture as a kind of antibiotic that low in cost, curative effect determines,
It not only can be used as water body bacteriostatic agent, but also can be added in bait, but since it belongs to tetracycline antibiotics, human body intake
" tetracycline pigmentation teeth " etc. can be led to the problem of after terramycin to be difficult to cure, in existing aquaculture technology, in application terramycin one
As need the off-drug period up to 30d that it can just be made to be down to 100 μ g/kg hereinafter, terramycin is in aquatic products in the intracorporal residual of aquatic products
There is more serious limitations for cultivation application.
Summary of the invention
One kind is provided it is an object of the invention to overcome in place of the shortcomings of the prior art, and can to reduce antibiotic residual
The medicinal fish feed stayed.
To achieve the above object, the technical scheme adopted by the invention is as follows: a kind of medicinal fish feed, including A agent and B agent, A
Agent includes bait, amino acid complex, vitamin C and terramycin, and B agent includes bait, amino acid complex, acetic acid, peroxidating
The bait that contains in hydrogen and potassium ferrate, A agent and B agent, the amount of amino acid complex are equal, and bait, 1-2 weight are contained in A agent
Part amino acid complex, the vitamin C of 0.1-0.5 parts by weight and the terramycin of 1 parts by weight, bait, 1-2 weight are contained in B agent
Measure the ferric acid of the amino acid complex of part, the acetic acid of 0.1-0.5 parts by weight, the hydrogen peroxide of 1-5 parts by weight and 2-8 parts by weight
Potassium.
Inventors discovered through research that by bait, amino acid complex, terramycin, vitamin C, potassium ferrate, peroxidating
After hydrogen, acetic acid are prepared into medicinal fish feed use, high degree reduces terramycin in the intracorporal residual of fish.
Preferably, the amino acid complex is at least one of methionine, histidine, L-aminobutanedioic acid.
Preferably, the weight ratio of terramycin and potassium ferrate is 1:5-8 in the medicinal fish feed.
Preferably, the weight ratio of terramycin and potassium ferrate is 1:5-6.5 in the medicinal fish feed.
Under above-mentioned weight proportion, after medicinal fish feed, high degree to reduce terramycin intracorporal in fish
Residual.
Preferably, the weight ratio of terramycin and hydrogen peroxide is 1:3-4 in the medicinal fish feed.
Under above-mentioned weight proportion, after medicinal fish feed, high degree to reduce terramycin intracorporal in fish
Residual.
Preferably, terramycin and ascorbic weight ratio are 1:0.3-0.5 in the medicinal fish feed.
Under above-mentioned weight proportion, after medicinal fish feed, high degree to reduce terramycin intracorporal in fish
Residual.
Preferably, the weight ratio of terramycin and bait is 1:800-1500 in the A agent of the medicinal fish feed.
The present invention also provides the preparation methods of any of the above-described medicinal fish feed, and the method includes following steps
It is rapid:
(1) bait, amino acid complex, vitamin C and terramycin are uniformly mixed by weight ratio, obtain medicinal fish
The A agent of feed；
(2) bait, amino acid complex and potassium ferrate are uniformly mixed by weight ratio, take acetic acid to match by weight ratio
Acetic acid solution is made, hydrogen peroxide is taken to be configured to hydrogenperoxide steam generator by weight ratio, when use by B agent acetic acid solution,
Hydrogenperoxide steam generator is uniformly mixed with the mixture of bait, amino acid complex and potassium ferrate in B agent.
The present invention also provides the application methods of any of the above-described medicinal fish feed, and the method includes following steps
It is rapid:
First the A agent of medicinal fish feed is launched, B agent is launched after 4-8 hour.
The beneficial effects of the present invention are: the present invention provides a kind of medicinal fish feed, medicinal fish of the invention is raised
Material can significantly reduce fish only intracorporal Determination of oxytetracycline residues, be applied to aquatic products so as to which terramycin drug is greatly reduced
Off-drug period when cultivation.
Detailed description of the invention
Fig. 1 is the weight ratio of terramycin and potassium ferrate in the medicinal fish feed of the embodiment of the present invention to Determination of oxytetracycline residues
Influence result.
Fig. 2 is the weight ratio of terramycin and hydrogen peroxide in the medicinal fish feed of the embodiment of the present invention to Determination of oxytetracycline residues
Influence result.
Fig. 3 is terramycin in the medicinal fish feed of the embodiment of the present invention and ascorbic weight ratio to Determination of oxytetracycline residues
Influence result.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 1 weight in B agent
Measure the hydrogen peroxide, the potassium ferrate of 2 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
The preparation method of the medicinal fish feed of the present embodiment the following steps are included:
(1) bait, amino acid complex, vitamin C and terramycin are uniformly mixed by weight ratio, obtain medicinal fish
The A agent of feed；
(2) bait, amino acid complex and potassium ferrate are uniformly mixed by weight ratio, take acetic acid to match by weight ratio
Acetic acid solution is made, hydrogen peroxide is taken to be configured to hydrogenperoxide steam generator by weight ratio, when use by B agent acetic acid solution,
Hydrogenperoxide steam generator is uniformly mixed with the mixture of bait, amino acid complex and potassium ferrate in B agent.
Embodiment 2
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 1 weight in B agent
Measure the hydrogen peroxide, the potassium ferrate of 3 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 3
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 1 weight in B agent
Measure the hydrogen peroxide, the potassium ferrate of 5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 4
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 1 weight in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 5
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 1 weight in B agent
Measure the hydrogen peroxide, the potassium ferrate of 8 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 6
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 2 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 7
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 3 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 8
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 9
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 5 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 10
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.1 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 11
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.2 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 12
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.4 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 13
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.5 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 14
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and L-aminobutanedioic acid that weight ratio is 1:1, bait, the amino contained in A agent and B agent
The amount of sour compound is equal, the vitamin C of amino acid complex, 0.5 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
Terramycin and 1200 parts by weight bait, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 in B agent
The bait of the hydrogen peroxide of parts by weight, the potassium ferrate of 6.5 parts by weight and 1200 parts by weight；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Embodiment 15
As a kind of medicinal fish feed of the embodiment of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of histidine and L-aminobutanedioic acid that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.5 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide, the potassium ferrate of 6.5 parts by weight and the bait of 1200 parts by weight of part；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Comparative example 1
As a kind of medicinal fish feed of comparative example of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 4 weights in B agent
Measure the hydrogen peroxide of part and the bait of 1200 parts by weight；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Comparative example 2
As a kind of medicinal fish feed of comparative example of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the vitamin C of amino acid complex, 0.3 parts by weight containing 1.5 parts by weight in A agent, 1 parts by weight
The bait of terramycin and 1200 parts by weight, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, 6.5 in B agent
The bait of the potassium ferrate of parts by weight and 1200 parts by weight；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Comparative example 3
As a kind of medicinal fish feed of comparative example of the present invention, including A agent and B agent, A agent include amino acid complex,
Vitamin C, terramycin and bait, B agent include amino acid complex, acetic acid, hydrogen peroxide, potassium ferrate and bait, the ammonia
Base acid compound is the mixture of methionine and histidine that weight ratio is 1:1, bait, the amino acid contained in A agent and B agent
The amount of compound is equal, the terramycin of amino acid complex, 1 parts by weight containing 1.5 parts by weight in A agent and 1200 parts by weight
Bait, the amino acid complex containing 1.5 parts by weight, the acetic acid of 0.1 parts by weight, the hydrogen peroxide of 4 parts by weight, 6.5 weights in B agent
Measure the potassium ferrate of part and the bait of 1200 parts by weight；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Comparative example 4
As a kind of medicinal fish feed of comparative example of the present invention, by the terramycin of 1 parts by weight and the bait of 1200 parts by weight
Material composition；
The bait by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, 8 parts by weight wheat bran and
The medical stone of 0.3 parts by weight forms.
Experimental example 1
For the antibiotic residue for verifying medicinal fish feed of the invention, pharmacological evaluation is carried out.
Using the childhood carp of health, 15 ± 1g of original body mass is divided into experimental group 1-15 and control group 1-4,
Experimental group 1-15 feeds the medicinal fish feed that embodiment 1-13 is obtained respectively, and control group 1-4 feeds control group 1-4
Medicinal fish feed.
The test pool is 100cm × 100cm × 100cm plastics pond, and every pond puts 30 tail carps, every group of 1 pond in a suitable place to breed.Feeding method
Are as follows: daily 9:00 launches the A agent of medicinal fish feed, and 16:00 launches the B agent of medicinal fish feed, daily medicinal fish feed
A agent feed that measure equivalent terramycin dosage be 60mg/kg weight, Feeding time is 7 days, and then every pond takes 5 tails to test at random
Fish carries out internal oxytetracycline residues detection to it, then continues to feed bait to experimental group 1-15 and control group 1-4, described
Bait is by the fish meal of 8 parts by weight, the dregs of beans of 15 parts by weight, the soya-bean oil of 2 parts by weight, the wheat bran of 8 parts by weight and the wheat of 0.3 parts by weight
Meal stone composition takes the test of 5 tails to carry out internal oxytetracycline residues detection with fish for every group at random again after continuing 7 days.
Be averaged residual quantity with the internal terramycin of control group 4 fish after raising 7 days only as 100, experimental result such as 1 institute of table
Show.
1 terramycin of table is averaged residual quantity
As shown in Table 1, the medicinal fish feed of 1-13 of the embodiment of the present invention can significantly reduce fish only intracorporal soil is mould
Element residual, so as to which off-drug period of the terramycin drug when being applied to aquaculture is greatly reduced, and it is real by comparison
Apply a 1-13 and comparative example 1-3's as a result, discovery embodiment medicinal fish feed using rear Determination of oxytetracycline residues significantly lower than pair
Ratio 1-3 illustrates that the potassium ferrate in medicinal fish feed, hydrogen peroxide, vitamin C are for reduction Determination of oxytetracycline residues and have weight
It acts on.
Comparing embodiment 1- embodiment 5 as a result, as shown in Figure 1, illustrating terramycin and ferric acid in medicinal fish feed
When the weight ratio of potassium is 1:5-6.5, after medicinal fish feed, terramycin is less in the intracorporal residual quantity of fish.
Comparing embodiment 4, embodiment 6- embodiment 9 as a result, as shown in Fig. 2, illustrating terramycin in medicinal fish feed
When weight ratio with hydrogen peroxide is 1:3-4, after medicinal fish feed, terramycin is less in the intracorporal residual quantity of fish.
Comparing embodiment 8, embodiment 10- embodiment 13 as a result, as shown in figure 3, in medicinal fish feed terramycin and
When ascorbic weight ratio is 1:0.3-0.5, after medicinal fish feed, terramycin is less in the intracorporal residual quantity of fish.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (9)
1. a kind of medicinal fish feed, which is characterized in that including A agent and B agent, A agent includes bait, amino acid complex, dimension life
Plain C and terramycin, B agent include bait, amino acid complex, acetic acid, hydrogen peroxide and potassium ferrate, are contained in A agent and B agent
Bait, the amount of amino acid complex are equal, and bait, the amino acid complex of 1-2 parts by weight, 0.1-0.5 parts by weight are contained in A agent
Vitamin C and 1 parts by weight terramycin, contain bait, the amino acid complex of 1-2 parts by weight, 0.1-0.5 weight in B agent
The acetic acid, the hydrogen peroxide of 1-5 parts by weight and the potassium ferrate of 2-8 parts by weight of part.
2. medicinal fish feed according to claim 1, which is characterized in that the amino acid complex be methionine,
At least one of histidine, L-aminobutanedioic acid.
3. medicinal fish feed according to claim 1, which is characterized in that terramycin and height in the medicinal fish feed
The weight ratio of potassium ferrite is 1:5-8.
4. medicinal fish feed according to claim 3, which is characterized in that terramycin and height in the medicinal fish feed
The weight ratio of potassium ferrite is 1:5-6.5.
5. according to claim 1, any medicinal fish feed of claim 3-4, which is characterized in that the medicinal fish
The weight ratio of terramycin and hydrogen peroxide is 1:3-4 in feed.
6. medicinal fish feed according to claim 5, which is characterized in that terramycin and dimension in the medicinal fish feed
The weight ratio of raw element C is 1:0.3-0.5.
7. medicinal fish feed according to claim 1, which is characterized in that soil is mould in the A agent of the medicinal fish feed
The weight ratio of element and bait is 1:800-1500.
8. the preparation method of medicinal fish feed as claimed in claim 1, which is characterized in that the method includes with
Lower step:
(1) bait, amino acid complex, vitamin C and terramycin are uniformly mixed by weight ratio, obtain medicinal fish feed
A agent；
(2) bait, amino acid complex and potassium ferrate are uniformly mixed by weight ratio, take by weight ratio peracetic acid formulation at
Acetic acid solution takes hydrogen peroxide to be configured to hydrogenperoxide steam generator by weight ratio, by acetic acid solution, the peroxide in B agent when use
Change hydrogen solution to be uniformly mixed with the mixture of bait, amino acid complex and potassium ferrate in B agent.
9. the application method of medicinal fish feed as claimed in claim 1, which is characterized in that the method includes with
Lower step:
First the A agent of medicinal fish feed is launched, B agent is launched after 4-8 hour.
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