CN110151306A - A kind of electric pulse parallel pole - Google Patents

A kind of electric pulse parallel pole Download PDF

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Publication number
CN110151306A
CN110151306A CN201910415420.9A CN201910415420A CN110151306A CN 110151306 A CN110151306 A CN 110151306A CN 201910415420 A CN201910415420 A CN 201910415420A CN 110151306 A CN110151306 A CN 110151306A
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CN
China
Prior art keywords
fine needle
electrodes
discharge active
electric discharge
active section
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Pending
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CN201910415420.9A
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Chinese (zh)
Inventor
陈永刚
孙婷婷
吕维敏
陈新华
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Rui Di Bio Tech Ltd Hangzhou
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Rui Di Bio Tech Ltd Hangzhou
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Priority to CN201910415420.9A priority Critical patent/CN110151306A/en
Priority to PCT/CN2019/101270 priority patent/WO2020232850A1/en
Publication of CN110151306A publication Critical patent/CN110151306A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22CALLOYS
    • C22C19/00Alloys based on nickel or cobalt
    • C22C19/03Alloys based on nickel or cobalt based on nickel
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/02Pretreatment of the material to be coated
    • C23C14/021Cleaning or etching treatments
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/06Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
    • C23C14/14Metallic material, boron or silicon
    • C23C14/16Metallic material, boron or silicon on metallic substrates or on substrates of boron or silicon
    • C23C14/165Metallic material, boron or silicon on metallic substrates or on substrates of boron or silicon by cathodic sputtering
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/22Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
    • C23C14/34Sputtering
    • C23C14/35Sputtering by application of a magnetic field, e.g. magnetron sputtering
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/58After-treatment
    • C23C14/5806Thermal treatment
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23GCLEANING OR DE-GREASING OF METALLIC MATERIAL BY CHEMICAL METHODS OTHER THAN ELECTROLYSIS
    • C23G1/00Cleaning or pickling metallic material with solutions or molten salts
    • C23G1/14Cleaning or pickling metallic material with solutions or molten salts with alkaline solutions
    • C23G1/20Other heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00107Coatings on the energy applicator
    • A61B2018/00148Coatings on the energy applicator with metal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00702Power or energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00982Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe

Abstract

The present invention relates to medical instruments field, especially a kind of electric pulse parallel pole.Existing electric pulse parallel pole gos deep into inside of human body and needs to do open wound, there are problems that increasing Principle of Pain, improves operation risk.The present invention provides a kind of electric pulse parallel poles to solve foregoing problems, it includes two electrodes, described two electrodes are fine needle made of Ultimum Ti, fine needle from front end backward formation length be T2 electric discharge active section, wrap up insulating layer in the fine needle surface of self discharge active section backward, two electrodes are set in same interposing catheter, and electric discharge active section can elasticity be unfolded after releasing interposing catheter forward and parallel opposite keeping parallelism space D 2, electric discharge active section end set guide frame.The present invention can be using noninvasive feeding inside of human body of endoscope passages such as endoscopic apparatus, or is directly entered in vivo through human body own channels, makees electric pulse ablation to tumor tissues, and ablation effect is good, and can infiltrate through tumor tissues for subsequent dose and create conditions.

Description

A kind of electric pulse parallel pole
Technical field
The present invention relates to medical instruments field, especially a kind of electric pulse parallel pole.
Background technique
The existing electric pulse for forming impulse electric field ablation tumour using two electrodes connecting with impulse generator is flat Row electrode, but this existing electric pulse parallel pole can only carry out percutaneous puncture in treating, suitable for the tumour close to skin Tissue;For the lesion of inside of human body tissue, due to the limitation of blood vessel on the way and nerve etc., it is difficult for electrode to be needled into lesion group Inside is knitted, thus must be external by pathological tissues exposure, it is treated, very big wound is caused to patient, increase patient's pain Pain and operation risk.
Summary of the invention
The technical problem to be solved in the present invention and the technical assignment of proposition are that existing electric pulse parallel pole gos deep into human body Portion needs to do open wound, increases Principle of Pain, improves the problems such as operation risk, the present invention provides a kind of electric pulse is parallel Electrode, the parallel pole can use the noninvasive feeding inside of human body of the endoscope passages such as endoscopic apparatus, or directly through human body from Body channel enters in vivo, carries out electric pulse ablation to tumor tissues, is then formed on tumour cell using aforementioned electric pulse Electroporation increases cell permeability and creates conditions for subsequent dose, so that enhancing tumor tissues ablation effect becomes possible.
The present invention solves the technical solution that technical problem uses: a kind of electric pulse parallel pole, including two electrodes, described Two electrodes are metal fine needle, and fine needle is from the front end electric discharge active section that formation length is T2 backward, self discharge active section Insulating layer is wrapped up on fine needle surface backward, it is characterized in that described two electrodes are set in same interposing catheter, the interposing catheter It can go deep into through human body natural's cavity or by scope service aisle internal, described two electrodes are made of Ultimum Ti Fine needle, the respective electric discharge active section of two electrodes can elasticity expansion and parallel opposite, two electric discharges after releasing interposing catheter forward The parallel spacing of active section is D2, and the end of two electric discharge active sections is equipped with guide frame.The present invention passes through two electrodes and intervention The combination of conduit enables parallel pole to enter inside of human body through human body natural's cavity or scope service aisle are noninvasive, then utilizes Guide frame guides two parallel poles inside tumor tissues, and electric discharge active section is close to tumor tissues, so that electrode surrounding Substantially it is wrapped up, tumour coverage rate is improved, more precise positioning ablated tumor by tumour;Two electric discharge active sections are releasing interposing catheter It is unfolded afterwards using shape memory effect elasticity, keeping parallelism is opposite, the energy after being powered after two electrodes connect impulse generator The electric field that even intensity is formed between two parallel poles, effectively shortens ablation time, increases the ablation area of single insertion, controls Therapeutic effect is good, greatly facilitates doctor and sufferer, not will increase Principle of Pain, while reducing operation risk;Two electric discharge active sections Only after releasing interposing catheter just can elasticity expansion and parallel opposite, draw back two electrodes after interposing catheter and collapse and be constrained in intervention and lead In the lumen of pipe.In addition, can also open micropore insertion on human body in conjunction with Minimally Invasive Surgery using the present invention and carry out successive treatment; In the use of the present invention, two parallel electrodes also need connection impulse generator, latter two electrode that is powered is respectively positive and negative electrode To form impulse electric field, the impulse generator is the prior art.
As further improving and supplementing to above-mentioned technical proposal, the present invention uses following technical measures: the guiding Structure is the two electric discharge active sections tips that respectively end is arranged.Two electric discharge working ends setting tip can be convenient directly be pierced into or It penetrates human body cavity wall to be pierced into inside tumor tissues, which needs image documentation equipment auxiliary to realize.
The guide frame is the guiding piece of a taper, and the electric discharge active section end of described two electrodes is fixed on same cone The guiding piece of shape, the bigger diameter end of guiding piece and the caliber of interposing catheter match, and two electrodes make two in guiding piece rear setting one The adjacent electrode fixuture of electrode, described two respective electric discharge active sections of electrode are between guiding piece and electrode fixuture. Structure on the fixed taper guiding piece in electric discharge active section end of this two electrodes is suitable for tumor tissues in approach channel week Situation on wall, two electric discharge active sections are bonded tumor tissues between tapered guide part and electrode fixuture, furthermore discharge The electrode at active section both ends all needs to do insulation processing.
The electric discharge active section corresponds to fine needle surface equipped with groove.Groove can increase the electrode section where electric discharge active section Surface area, and then increase material launching electronics number, when the fine needle of electrode is close to tumor tissues, these grooves can increase electrode Surface area, make electron emission quantity increase, improve electric pulse parallel pole work when electric field density.
The groove is the annular groove that fine needle surface is spaced apart along fine needle length direction, or is fine needle surface along fine needle The continuous helicla flute of length direction, or be circumferential zigzag slot.Groove can be the independent annular groove being spaced apart, can also To be continuous helicla flute, or circumferential zigzag slot, effect are provided to increase surface area raising electric field density, add simultaneously Strong development effect.
The fine needle of described two electrodes is that Ultimum Ti of the nickel mass fraction between 54.5%-57.0% is made, Tantalum is plated on the corresponding fine needle surface of the electric discharge active section, and fine needle made of the Ultimum Ti uses magnetron sputtering coater Carry out plating tantalum, sputtering power 90W when plated film, 120 DEG C of substrate temperature, sputtering pressure 0.45Pa, sputtering time 240 minutes;Plate tantalum The thickness of layer is annealed 1.2 hours at 1~5 μm, and after plating tantalum at 800 DEG C.Electrode is using nickel mass fraction in 54.5%-57.0% Between Ultimum Ti be made, the critical load of the tantalum coating that the sputter coating obtains and nickel-titanium memory alloy-based body is super 70N is crossed, the two, which combines to consolidate, meets medical application requirement, radiography visibility is improved in parallel pole galvanization, specifically The radiation opaque for improving electrode facilitates two electrodes of positioning when operation precisely to enter tumor tissues;In 800 DEG C of height after plating tantalum Temperature annealing 1.2 hours, electrode surface metallographic hard, crisp, poor chemical stability by β-Ta(material) be changed into α-Ta(material more have it is tough Property, chemical stability is good), while coating surface is uniform, finish is good, it is more smooth in subsequent insertion tumor tissues.According to solid Electron theo ry on metal in body physics, since, there are potential barrier Wb, electronics will escape necessary from metal between metal surface and the external world Energy Wb is at least obtained, the function that this electronics overcomes surface potential barrier that must do when escaping from metal surface is work function, the evolution Function size has decisive action to electron emission power, and the fine needle of electrode is made and plates tantalum using Ultimum Ti here, then Annealing can greatly increase the evolution quantity of electronics under high-voltage pulse, improve electric field density, enhance ablation effect.
Fine needle made of the Ultimum Ti needs to do following processing before plating tantalum: roughening, blasting treatment;Oil removing, It is heated 30 minutes using alkaline chemical solution, then deionized water is cleaned repeatedly, then is dried after ten minutes with acetone ultrasonic cleaning. Tantalum coating can be improved by the treatment process and be attached to firmness on nickel-titanium memory alloy-based body, alkali described in actual use Property chemical solution be 60g/L oxygen sodium oxide molybdena and 80g/L sodium carbonate mixing liquid.
The present invention provides a kind of electric pulse parallel pole, the parallel pole can use the scopes work such as endoscopic apparatus Make the noninvasive feeding inside of human body in channel, or directly enter in vivo through human body natural's cavity, electric pulse ablation is carried out to tumor tissues, Then increase cell permeability on tumour cell using aforementioned electric pulse, create conditions for subsequent dose, to further increase Possible is become to the ablation effect of tumor tissues.
Detailed description of the invention
Fig. 1: 1 structural schematic diagram of embodiment.
Fig. 2: the electrode structure schematic diagram of embodiment 1.
Fig. 3: 1 operation schematic diagram of embodiment.
Fig. 4: the electric discharge active section schematic diagram of 1 electrode of embodiment.
Fig. 5: 2 operation schematic diagram of embodiment.
In figure: 1. electrodes, 2. electrodes, 3. insulating layers, 4. interposing catheters, 5. guide frames, 6. electrode fixutures, 7. human bodies Cavity wall, 8. tumor tissues, 9. grooves.
Specific embodiment
The present invention is described further with specific embodiment for explanation with reference to the accompanying drawing.
Embodiment 1 as shown in figures 1-4, a kind of electric pulse parallel pole, including electrode 1 and electrode 2, described two electrodes It is metal fine needle, and fine needle is from the front end electric discharge active section that formation length is T2 backward, self discharge active section backward thin Wire surface wraps up insulating layer 3, and two electrodes are set in same interposing catheter 4, the interposing catheter 4 can through human body natural's cavity or Go deep by scope service aisle internal, described two electrodes are fine needle made of Ultimum Ti, and two electrodes are respectively Electric discharge active section can the elasticity expansion and parallel opposite after releasing interposing catheter forward, the parallel spacing of two electric discharge active sections is The end of D2, two electric discharge active sections are equipped with guide frame 5, and the guide frame in the present embodiment is two electric discharge active sections respectively end The tip of setting.
When work, the elasticity expansion after releasing interposing catheter of the electric discharge active section of two electrodes, keeping parallelism is opposite, then Two electric discharge active sections are directed through human body cavity wall 7 using the tip of end and are pierced into inside tumor tissues 8, keep electric discharge active section tight Tumor tissues are pasted, electrode surrounding is wrapped up by tumour substantially, is improved to tumour coverage rate, more precise positioning ablated tumor, described two A electrode connects impulse generator in advance, and impulse generator latter two electrode that is powered becomes one positive one negative, positive and negative electrode it Between generate impulse electric field to tumour ablation, two electrode power offs, which are drawn back interposing catheter and collapsed, after ablation is constrained in interposing catheter Lumen in;Two electric discharge active section elasticity expansion after releasing interposing catheter, keeping parallelism is opposite, forms the electricity of even intensity , shorten ablation time, increases the ablation area of single insertion, therapeutic effect is good, greatly facilitates doctor and sufferer, Bu Huizeng Add Principle of Pain, while reducing operation risk.
Further, above-mentioned electric discharge active section corresponds to fine needle surface and is equipped with groove 9, and the groove in the present embodiment is preferably thin In addition it is continuous along fine needle length direction to be also possible to fine needle surface for the annular groove that wire surface is spaced apart along fine needle length direction Helicla flute, or circumferential zigzag slot.The surface area that the electrode section where electric discharge active section can be increased using groove, into And increase material launching electronics number, when the fine needle of electrode is thrusted straightly into tumor tissues, these grooves can increase the surface area of electrode, make Electron emission quantity increases, and improves the electric field density formed when the work of electric pulse parallel pole;These grooves can be with simultaneously Enhance development effect, electrode is facilitated to be accurately positioned.
The fine needle of described two electrodes is Ultimum Ti of the nickel mass fraction between 54.5%-57.0%, specifically It is using Ti-50.8at.%Ni, nickel mass fraction is made of 55.9% Ultimum Ti, then in electric discharge active section pair Tantalum is plated on the fine needle surface answered, and fine needle made of Ti-50.8at.%Ni memorial alloy carries out plating tantalum using magnetron sputtering coater, plates Sputtering power 90W when film, 120 DEG C of substrate temperature, sputtering pressure 0.45Pa, sputtering time 240 minutes;The thickness of tantalum layer is plated 1 ~5 μm, and anneal 1.2 hours after plating tantalum at 800 DEG C.Fine needle made of the Ti-50.8at.%Ni memorial alloy is in plating tantalum Before need to do following processing: roughening, blasting treatment;Oil removing is heated 30 minutes using alkaline chemical solution, and then deionized water is anti- Multiple cleaning, then dried after ten minutes with acetone ultrasonic cleaning.The tantalum coating that sputter coating obtains and nickel-titanium memory alloy-based body Critical load is more than 70N, and the two, which combines to consolidate, meets medical application requirement, and it is visual that radiography is improved in parallel pole galvanization Degree specifically improves the radiation opaque of electrode, and two electrodes of positioning when operation is facilitated precisely to enter tumor tissues;After plating tantalum 800 DEG C high annealing 1.2 hours, electrode surface metallographic hard, crisp, poor chemical stability by β-Ta(material) be changed into α-Ta (material more flexible, chemical stability are good), while coating surface is uniform, finish is good, more in subsequent insertion tumor tissues It is smooth.The fine needle of electrode is made and plates tantalum using Ultimum Ti, then makes annealing treatment, can be significantly under high-voltage pulse Increase the evolution quantity of electronics, improve electric field density, enhances ablation effect.
Embodiment 2 is as shown in figure 5, a kind of electric pulse parallel pole and the difference place of embodiment 1 are the guiding knot Structure 5 is the guiding piece of a taper, and the electric discharge active section end of the electrode 1 and electrode 2 is fixed on the guiding piece of same taper, The bigger diameter end of guiding piece and the caliber of interposing catheter 4 match, and two electrodes keep two electrodes adjacent in guiding piece rear setting one Electrode fixuture 6, the electrode section between guiding piece and electrode fixuture 6 include the respective electric discharge active section of two electrodes, electric discharge The electrode surface at active section both ends has insulating layer, and rest part and embodiment 1 are identical.When work, this two electrodes are put Structure on the fixed taper guiding piece in electric active section end is suitable for situation of the tumor tissues on approach channel circumference wall, due to Active section both ends discharge respectively by the constraint of puncture tip and electrode fixuture, tapered guide part is along human body cavity wall 7 when work It guides interposing catheter 4 to reach 8 position of tumor tissues, then draw back interposing catheter while releasing two electrodes, two electrodes Elasticity expansion and parallel opposite, two electric discharge active sections between tapered guide part and electrode fixuture after releasing interposing catheter Tumor tissues are bonded, the ablation that is powered finishes latter two electrode and draws back interposing catheter collapses the lumen for being constrained in interposing catheter again In.

Claims (7)

1. a kind of electric pulse parallel pole, including two electrodes (1,2), described two electrodes are metal fine needle, and fine needle is certainly Insulating layer (3) are wrapped up on the front end electric discharge active section that formation length is T2 backward, the fine needle surface of self discharge active section backward, It is characterized in that described two electrodes (1,2) is set in same interposing catheter (4), the interposing catheter (4) can be through human body natural's cavity Or go deep by scope service aisle internal, described two electrodes (1,2) are fine needle made of Ultimum Ti, two electricity Extremely respective electric discharge active section can the elasticity expansion and parallel opposite after releasing interposing catheter forward, two electric discharge active sections it is parallel Spacing is D2, and the end of two electric discharge active sections is equipped with guide frame (5).
2. electric pulse parallel pole according to claim 1, it is characterized in that the guide frame (5) is two electric discharge active sections The tip of respective end setting.
3. electric pulse parallel pole according to claim 1, it is characterized in that the guide frame (5) is the guidance of a taper The electric discharge active section end of part, described two electrodes (1,2) is fixed on the guiding piece of same taper, the bigger diameter end of guiding piece and The caliber of interposing catheter (4) matches, and two electrodes (1,2) make the adjacent electrode fixuture of two electrodes in guiding piece rear setting one (6), described two respective electric discharge active sections of electrode (1,2) are located between guiding piece and electrode fixuture (6).
4. according to claim 1 to electric pulse parallel pole described in one of 3, it is characterized in that the electric discharge active section corresponds to fine needle Surface is equipped with groove (9).
5. electric pulse parallel pole according to claim 4, it is characterized in that the groove (9) is that fine needle surface is long along fine needle The annular groove that is spaced apart of degree direction, perhaps be fine needle surface along the continuous helicla flute of fine needle length direction or be that circumferential direction is sawed The slot of tooth form.
6. electric pulse parallel pole according to one of claims 1 to 5, it is characterized in that described two electrodes (1,2) is thin Needle is that Ultimum Ti of the nickel mass fraction between 54.5%-57.0% is made, the corresponding fine needle of the electric discharge active section Tantalum is plated on surface, and fine needle made of the Ultimum Ti carries out plating tantalum using magnetron sputtering coater, sputtering power when plated film 90W, 120 DEG C of substrate temperature, sputtering pressure 0.45Pa, sputtering time 240 minutes;The thickness of tantalum layer is plated at 1~5 μm, and is plated It anneals 1.2 hours after tantalum at 800 DEG C.
7. electric pulse parallel pole according to claim 6, it is characterized in that fine needle made of the Ultimum Ti exists Need to do following processing before plating tantalum: roughening, blasting treatment;Oil removing is heated 30 minutes, then deionization using alkaline chemical solution Water cleans repeatedly, then is dried after ten minutes with acetone ultrasonic cleaning.
CN201910415420.9A 2019-05-17 2019-05-17 A kind of electric pulse parallel pole Pending CN110151306A (en)

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CN201910415420.9A CN110151306A (en) 2019-05-17 2019-05-17 A kind of electric pulse parallel pole
PCT/CN2019/101270 WO2020232850A1 (en) 2019-05-17 2019-08-19 Electrical pulse-related parallel electrodes

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