CN109966407A - Train first live-nourishing ' yanggan ' pill - Google Patents

Train first live-nourishing ' yanggan ' pill Download PDF

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CN109966407A
CN109966407A CN201910380128.8A CN201910380128A CN109966407A CN 109966407 A CN109966407 A CN 109966407A CN 201910380128 A CN201910380128 A CN 201910380128A CN 109966407 A CN109966407 A CN 109966407A
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parts
stir
liver
nourishing
kidney
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CN109966407B (en
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戴丽冰
王琪琳
温蕊瑜
朱志琼
王琼芳
周葵
刘益杉
康国娇
谢菠
李加云
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Puer Traditional Chinese Medicine Hospital
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Puer Traditional Chinese Medicine Hospital
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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Abstract

It is infertile caused by solving the problems, such as because of caused by liver and kidney deficiency the present invention relates to a kind of training member live-nourishing ' yanggan ' pill for improving infertile constitution.The effective component of the pharmaceutical composition, it is made by weight of following raw material: 17-22 parts of Rehmannia glutinosa, 14-17 parts of Fructus Corni, 19-23 parts of fructus lycii, 14-18 parts of Semen Cuscutae, 14-18 parts of stir-baked CORTEX EUCOMMIAE with salt solution, 13-16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 13-16 parts of Radix Angelicae Sinensis, 14-16 parts of Radix Salviae Miltiorrhizae, 18-21 parts of Chinese yam, 16-22 parts of Poria cocos, 17-21 parts of the fruit of glossy privet, 18-22 parts of Eclipta prostrata, 19-22 parts of longspur epimedium, 15-18 parts of Herba Cistanches, 9-14 parts of radix achyranthis bidentatae.It uses this drug therapy caused by liver and kidney deficiency to have significant curative effect for the infertility of the cause of disease, is only taken in this drug therapy case statistics in certain time, sum 30, effective percentage 80%, cure rate 66.6%.

Description

Train first live-nourishing ' yanggan ' pill
Technical field
The present invention relates to drug infertile caused by caused by liver and kidney deficiency, especially a kind of training member live-nourishing ' yanggan ' pill for improving infertile constitution.
Background technique
Infertile medical definition is not take any contraceptives in, and sexual life is normally without successful pregnancy.Mainly It is divided into primary infertility and secondary infertility.Primary infertility is never to become pregnant；Secondary infertility is that once pregnancy was later and infertile.According to this The stringent definition of kind, infertile is a kind of common problem, about influences at least 10%~15% couple at child-bearing age.Cause infertile Pathogenic factor is divided into male infertility and female acyesis.
The deficiency of the liver-yin is also known as deficiecny of liver-YIN, and it is unsuccessful by feelings will to refer to, qi depression transforming into fire；Or the warm heat disease later period, consumption impariment of the liver yin；Or kidney yin Deficiency, water files to nourish wood, the yin-fluid virtual loss of caused liver and interior hot upper harassing syndrome is waited.Symptoms include dizziness and tinnitus, two xerophtalmias, eyesight subtract It moves back, Facial flush or cheekbone are red, and dryness of the mouth and throat is dysphoria in chestpalms-soles, hectic fever night sweat or the indistinct cusalgia of side of body rib or wriggling of limbs etc..It controls preferably Based on nourishing yin and nourishing liver.Chinese medicine says " The liver and the kidney have a common source ", also known as " yi and Kui are derived from the same origin ", " essence and blood sharing the same origin ", i.e. blood stored in the liver, kidney storing essence, smart energy Green blood, blood generating essence.Kidney essense and liver blood, Rong Zetong is flourish, declines, same to decline.The liver belonging to wood, kidney category water, kidney water can nourish edema with the liver involved, add Kidney yin be that the whole body yin-fluid is basic, therefore the deficiency of the kidney yin, water files to nourish wood, then causes deficiecny of liver-YIN so as to cause deficiency and exhaustion of liver-YIN.Kidney It is empty it is infertile be a kind of female body symptom, have the women of this symptom mostly insufficient because possesing, kidney essense is not filled, menses cannot on time and Extremely, or to conception vessel void without containing, is rushed, vessels of the uterus dystrophy cannot take the photograph essence at pregnant.
As environmental pollution is serious, rhythm of life is accelerated, operating pressure increases, the change and outlook on childbirth of dietary structure Transformation, infertile problem is also increasingly prominent to be come out.The disease incidence of China's infertility about 15%, wherein 60% leads for female factors What is caused is infertile, this seriously affects patient's physical and mental health, leads to many social concerns.Therefore, pregnancy rate how is improved to receive much attention. The development of modern reproductive medicine brings Gospel for many infertile patients and family.But there is also one for modern medical techniques A little problems, such as current existing hormone therapy, side effect is big, pregnancy rate is low, expense is higher, and patient is difficult to adhere to medication.In and Doctor systematically studies women's physiological, pathological characteristic from macroscopic perspective, and with whole conditioning, adverse reaction is small, late result is good Characteristic and advantage.So exploring, clinical efficacy is definite, and safety, reasonable, science, the recipe gesture easily by many patients receiving exist It must go.
Summary of the invention
In order to overcome the disadvantages mentioned above of the prior art, the present invention provides one kind and tonifies the liver and kidney, regulating menstruation and assisting pregnancy；Cure mainly liver deficiency of the kidney The training member live-nourishing ' yanggan ' pill of infertile caused by void, irregular menstruation, the infertile constitution of improvement of premature ovarian failure, menopausal disorders.
The technical solution adopted by the present invention to solve the technical problems is: train first live-nourishing ' yanggan ' pill, the pharmaceutical composition it is effective Ingredient is made by weight of following raw material: 17-22 parts of Rehmannia glutinosa, 14-17 parts of Fructus Corni, 19-23 parts of fructus lycii, Semen Cuscutae 14- 18 parts, 14-18 parts of stir-baked CORTEX EUCOMMIAE with salt solution, 13-16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 13-16 parts of Radix Angelicae Sinensis, 14-16 parts of Radix Salviae Miltiorrhizae, 18-21 parts of Chinese yam, Poria cocos 16- 22 parts, 17-21 parts of the fruit of glossy privet, 18-22 parts of Eclipta prostrata, 19-22 parts of longspur epimedium, 15-18 parts of Herba Cistanches, 9-14 parts of radix achyranthis bidentatae.
More excellent formula is 19-21 parts of Rehmannia glutinosa, 15-16 parts of Fructus Corni, 19-21 parts of fructus lycii, 15-18 parts of Semen Cuscutae, salt Du 14-15 parts secondary, 13-15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15-16 parts of Radix Angelicae Sinensis, 15-16 parts of Radix Salviae Miltiorrhizae, 19-20 parts of Chinese yam, 19-22 parts of Poria cocos, glossy privet 19-21 parts sub-, 20-22 parts of Eclipta prostrata, 19-20 parts of longspur epimedium, 15-16 parts of Herba Cistanches, 9-12 parts of radix achyranthis bidentatae.
Above-mentioned raw materials medicinal material is formed as active ingredient and pharmaceutic adjuvant, is taken by being processed into pill.Or usage: Cold water is fried boiling 20 minutes, and juice is taken to warmly take after meal.
The sweet Wen Zhirun of Rehmannia glutinosa in side, yin-nourishing of enriching blood, beneficial to spirit and marrow are monarch drug in a prescription；Fructus Corni, it is sweet, flat, can invigorating the spleen, reinforce the kidney, Strengthening the essence；Fructus lycii, it is sweet, flat, can be nourishing liver and kidney, benefiting shrewd head；Semen Cuscutae, it is sweet, flat, for the key medicine of flat tonifying liver spleen kidney, can kidney tonifying it is solid Essence, liver-benefiting eye-brightening, invigorating the spleen to arrest diarrhea；Stir-baked CORTEX EUCOMMIAE with salt solution, it is pungent, warm, can nourishing liver and kidney, strengthening the bones and muscles, miscarriage prevention；Stir-baked RHIZOMA POLYGONATI with yellow rice wine, nature and flavor are sweet, flat, enter spleen, Kidney, lung channel have the function of air making-up and spleen enlivening, moistening lung, kidney-nourishing.Fructus Corni, fructus lycii, Semen Cuscutae, stir-baked CORTEX EUCOMMIAE with salt solution, stir-baked RHIZOMA POLYGONATI with yellow rice wine are ministerial drug, auxiliary Principal drug assistance reinforces the function of its help to effect a permanent cure, and liver kidney is with mending, in the hope of The liver and the kidney have a common source, essence and blood alternate；Radix Angelicae Sinensis, it is sweet, pungent, warm, it can support Liver blood and menstruation regulating；Radix Salviae Miltiorrhizae, bitter, cold nature are apt to activating microcirculation and removing stasis medicinal menstruation regulating；Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae are adjutant promoting blood circulation for regulating menstruation to treat the symptoms；Mountain Medicine, it is sweet, flat, can invigorating the spleen, tonifying lung, reinforce the kidney；Three dirty all benefits；Poria cocos, it is sweet, light, it can inducing diuresis with bland drug；Keep day after tomorrow qi and blood metaplasia active； The fruit of glossy privet, Eclipta prostrata are nourishing liver and kidney；Herba Epimedii, Herba Cistanches warming kidney and enhancing yang；Radix achyranthis bidentatae: bitter, sour, flat.Return liver kidney channel, nourishing liver and kidney, Strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow are ensuringd proper downward flow of the blood.All medicines share, treating both manifestation and root cause of disease, through-supplementation are mended without stagnant, and row is without dissipating.Benefit is played altogether Liver and kidney benefiting, the function of regulating menstruation and assisting pregnancy.
Modern pharmacological research shows that having the Chinese medicine for promoting gonad function is mostly the Chinese medicine of kidney tonifying, strengthening the essence.Zhang Xiaohong etc. By the experimental study data of the influence to kidney-reinforcing drug in recent years to ovarian function and endometrium, find kidney-nourishing tcm drug to ovary function Energy and sub- inner membrance have the effect of parahormone sample, can adjust hypothalamo pituitary ovary s function；Promote ovarian follicular growth and ovulation induction；Regulate and control phase Close cell because and its acceptor levels；Integrally-regulated sex hormone and its acceptor levels；Improve endometrium rush to become pregnant, thus into one Walk illustrates that kidney-nourishing tcm drug truly has curative effect to the recovery of ovarian function and the improvement of status of endometrium.Semen Cuscutae has estrogen-like work With controllable gonad axis promotes corpus luteum function, increases uterus weight and keeps vagina epithelium cutinization the most significant； Kidney-yang deficiency hypothalamus of animals corticoliberim secretory volume can be improved in cornel extractive, adjusts hypothalamus- Hypophysis-adrenal cortex axis function；Radix Angelicae Sinensis can promote developing womb, and menstrual period are normal；Fructus lycii can increase the weight of hypophysis and ovary Amount, improves neuroendocrine adjusting, has and induces Effect of Ovulation.
The invention has the following advantages: being shown by numerous clinical pharmacology research, kidney-nourishing tcm drug has menstruation regulating, promotees It ovulates, help important function that is pregnant and promoting early embryonic development.The woman is based on the liver, and treat from liver gynecological disease is also important Link." Ling Shu Miraculous Pivot or Divine Axis passages through which vital energy circulates " is said: " the liver meridian of Foot-JUE YIN follows stock yin, enters in hair, ring external genitals, supports underbelly ", the process out of shape of Liver Channel Underbelly, external genitals, this also illustrates that liver and reproduction and gynecological disease are closely related.Therefore Clinical Selection tonifies the liver and kidney, regulating menstruation and assisting pregnancy Drug therapy is infertile, harvests good effect.
Specific embodiment
First live-nourishing ' yanggan ' pill is trained, which is to start medication for menstruation the 5th day, continuous use 8-10 days.
Embodiment 1
First live-nourishing ' yanggan ' pill is trained, the effective component of the pharmaceutical composition is made by weight of following raw material: 19 grams of Rehmannia glutinosa, mountain Zhu 16 grams of cornel, 19 grams of fructus lycii, 18 grams of Semen Cuscutae, 14 grams of stir-baked CORTEX EUCOMMIAE with salt solution, 15 grams of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15 grams of Radix Angelicae Sinensis, 16 grams of Radix Salviae Miltiorrhizae, 19 grams of Chinese yam, 22 grams of Poria cocos, 19 grams of the fruit of glossy privet, 20 grams of Eclipta prostrata, 19 grams of longspur epimedium, 16 grams of Herba Cistanches, 11 grams of radix achyranthis bidentatae.
Typical case 1, Lee XX, Yunnan people from Pu'er, first visit on March 23 in 2015,28 years old, patient was because of " unpregnancy two of not practising contraception Year has a surplus " it sees a doctor, patient's readme rule of menstruation usually prepares pregnancy, without living in separate places, sexual life is normal, does not keep away from 2013 Pregnant unpregnancy so far.Gynecologial examination: vulva wedding shape, vagina is unobstructed, and uterine neck is slightly rotten to the corn, no act pendulum pain.Anteversion of uterus, no tenderness, Double accessory is obviously normal.Diagnosis: infertility (caused by liver and kidney deficiency).
From on March 23rd, 2015,6 doses of format application prescription, interval further consultation in 7-15 days is primary, the accumulative further consultation number two in centre More than ten times, 6 doses of this prescription medicinal material are issued every time, usage: cold water soak 30 minutes, are fried boiling 20 minutes, decoct twice, take juice 600ml, It takes 200ml 1 time, three times a day, warmly takes after meal.To take this drug be further consultation on December 25 in 2015 to last time, medical history as before, It does not go within menstruation 5 days, now feels underbelly secret anguish, contraception in nearly January, red tongue with thin fur, arteries and veins is fine and smooth.
Further consultation on January 4 in 2016, medical history is not as before, opsomenorrhea half a month goes, and urine pregnancy test is positive, red tongue with thin fur, arteries and veins It is fine and smooth.Diagnosis: early pregnancy cuts out this drug.Effect of follow-up visit by telephone: in 1 girl baby of Cesarean esction on the 28th of August in 2016.
Embodiment 2
First live-nourishing ' yanggan ' pill is trained, the effective component of the pharmaceutical composition is made by weight of following raw material: Rehmannia glutinosa 20g, Chinese yam 20g, Fructus Corni 15g, Radix Angelicae Sinensis 15g, stir-baked CORTEX EUCOMMIAE with salt solution 15g, Poria cocos 20g, Semen Cuscutae 15g, fructus lycii 20g, Radix Salviae Miltiorrhizae 15g, fruit of glossy privet 20g, Eclipta prostrata 20g, stir-baked RHIZOMA POLYGONATI with yellow rice wine 15g, Herba Epimedii 20g, Herba Cistanches 15g, radix achyranthis bidentatae 12g.
Typical case 2, Tan XX, Pu'er Municipal Forestry Bureau, first visit on July 28 in 2016,29 years old, patient was not because " practising contraception 3 years It is remaining " it sees a doctor, patient's readme menstruation irregularis, the menstrual cycle 40-60 days；Once 1 girl baby of Cesarean esction before this prepares bosom two from 2013 Tire, without living in separate places, sexual life is normal, unpregnancy so far of not practising contraception, once shows follicular dysplasia, intrauterine in outer court's monitoring ovulation Film is partially thin, and it is ineffective repeatedly to take western medicines in treatment.B ultrasound monitoring display: right ovary scrotum sample changes, no follicular development, urine Inspection is negative, inner membrance 0.3cm, opens first five doses of the live-nourishing ' yanggan ' pill of training, usage: cold water soak 30 minutes, being fried boiling 20 minutes, decocts twice, takes juice 600ml, takes 200ml 1 time, three times a day, warmly takes after meal.Period further consultation more than ten times, the application drug is taken, to November 4 in 2016 Day further consultation, monitoring on November 3 ovarian follicle: right side ovarian follicle 1.8cm*1.6cm, inner membrance 0.68cm, the further consultation same day monitor ovarian follicle: having arranged Out, inner membrance 0.8cm.The first live-nourishing ' yanggan ' pill of 6 doses of trainings is opened again to take, and advises its same branch of a family.
Further consultation on December 2 in 2016, readme November 20 look into B ultrasound from urine pregnancy test weakly positive, the further consultation same day is surveyed: in utero Pregnant 5+ weeks, early pregnancy is diagnosed, this drug is cut out.Effect of follow-up visit by telephone, on July 11st, 2,017 1 boy baby of Cesarean esction.
Embodiment 3
First live-nourishing ' yanggan ' pill is trained, the effective component of the pharmaceutical composition is made by weight of following raw material: 21 grams of Rehmannia glutinosa, mountain Zhu 15 grams of cornel, 21 grams of fructus lycii, 16 grams of Semen Cuscutae, 15 grams of stir-baked CORTEX EUCOMMIAE with salt solution, 14 grams of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 16 grams of Radix Angelicae Sinensis, 15 grams of Radix Salviae Miltiorrhizae, 19 grams of Chinese yam, 19 grams of Poria cocos, 21 grams of the fruit of glossy privet, 21 grams of Eclipta prostrata, 19 grams of longspur epimedium, 16 grams of Herba Cistanches, 11 grams of radix achyranthis bidentatae.
Typical case 3, warm XX, the firmly source Puer City Shui Yinglin, first visit on May 17 in 2017,28 years old, unpregnancy one of not practising contraception Year, five days menstrual period are net, and closely menstrual flow gradually decreases over the past half year, last menstrual period: on May 2nd, 2017, and few through measuring, color is dark red, press from both sides blood Block is ached with lower abdomen, and soreness of waist pain prepares pregnancy from 2016, without living in separate places, sexual life is normal.Existing symptom: soreness of waist pain, band Lower normal, two is just clear, and tongue is red slightly flat, and tongue fur is few, and arteries and veins is thin.Diagnosis: infertility (caused by liver and kidney deficiency) opens five Fu Peiyuan live-nourishing ' yanggan ' pills, and bag is decocted. Period further consultation more than 20 times, the application drug is taken, cold water soak 30 minutes, is boiled 20 minutes, decocted twice, packaging, one day one Agent, 3 times/day, one bag primary, takes orally.
Further consultation on the 27th in 2 months in 2018, patient's readme menstruation on the 14th in 2 months are not gone, and from urine pregnancy test weakly positive is surveyed, further consultation is worked as Day looks into B ultrasound: in utero pregnant 6+ weeks, diagnosis: early pregnancy cut out this drug.On May 16th, 2018, Effect of follow-up visit by telephone: without discomfort.B ultrasound Show: in utero pregnant, single tire living；The 17+ weeks size estimation moon of fetus.
Typical case 4, Lee XX, the Puer City stockaded village Dao Guang, first visit on April 9 in 2018,33 years old, patient was because of " unpregnancy 2 of not practising contraception Year " see a doctor, because infertile inspections is shown: bilateral salpingo blocks, in temporary dwelling palace laparoscopic surgery on March 1st, 2018, it is postoperative invariably It is suitable, follicular dysplasia is surveyed, clomiphene is now taken.Existing symptom: the red tongue fur of tongue is few, slippery.Diagnosis: infertility (caused by liver and kidney deficiency).It opens Take the first live-nourishing ' yanggan ' pill of 6 doses of trainings.Hereafter further consultation more than 20 times during, take the application drug, and packed for decocting, one is one, and 3 times/day, One bag primary, and cold water decocts, and boils 20 minutes, takes orally.
The further consultation on the 10th of August in 2018, readme July 29 day by day vagina bleed a little 1 day it is net, August 9 days is from surveying urine pregnancy test The positive, now sense nausea is 2 days uncomfortable, looks into B ultrasound and shows: in utero pregnant 5+ weeks, diagnosing early pregnancy (threatened abortion), withdrawal.
In addition to above-mentioned typical case, this drug therapy caused by liver and kidney deficiency is used to have significant curative effect, one for the infertility of the cause of disease It fixes time and only takes in this drug therapy case statistics, sum 30, effective percentage 80%, cure rate 66.6%.This drug therapy mesh Preceding depth has also been attracted the patient of neighbouring area and surrounding countries to hospital by the trust of many patients in addition to this city, is received good Good social benefit.

Claims (2)

1. training first live-nourishing ' yanggan ' pill, the effective component of the pharmaceutical composition is made by weight of following raw material: 17-22 parts of Rehmannia glutinosa, 14-17 parts of Fructus Corni, 19-23 parts of fructus lycii, 14-18 parts of Semen Cuscutae, 14-18 parts of stir-baked CORTEX EUCOMMIAE with salt solution, 13-16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, Radix Angelicae Sinensis 13-16 Part, 14-16 parts of Radix Salviae Miltiorrhizae, 18-21 parts of Chinese yam, 16-22 parts of Poria cocos, 17-21 parts of the fruit of glossy privet, 18-22 parts of Eclipta prostrata, longspur epimedium 19- 22 parts, 15-18 parts of Herba Cistanches, 9-14 parts of radix achyranthis bidentatae.
2. training first live-nourishing ' yanggan ' pill as described in claim 1, it is characterised in that: 19-21 parts of Rehmannia glutinosa, 15-16 parts of Fructus Corni, fructus lycii 19-21 parts, 15-18 parts of Semen Cuscutae, 14-15 parts of stir-baked CORTEX EUCOMMIAE with salt solution, 13-15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15-16 parts of Radix Angelicae Sinensis, 15-16 parts of Radix Salviae Miltiorrhizae, mountain 19-20 parts of medicine, 19-22 parts of Poria cocos, 19-21 parts of the fruit of glossy privet, 20-22 parts of Eclipta prostrata, 19-20 parts of longspur epimedium, Herba Cistanches 15-16 Part, 9-12 parts of radix achyranthis bidentatae.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111632108A (en) * 2020-07-02 2020-09-08 贾锐 Medicine for treating infertility

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CN101049397A (en) * 2007-05-16 2007-10-10 北京艺信堂医药研究所 Composition of Chinese traditional medicine for treating barrenness caused by premature ovarian failure
CN103393879A (en) * 2013-07-24 2013-11-20 赵世明 Traditional Chinese medicine composition for treating liver and kidney deficiency
CN104758854A (en) * 2015-04-28 2015-07-08 高纪英 Chinese herba preparation for treating premature ovarian failure
CN105748916A (en) * 2016-04-06 2016-07-13 柳州市妇幼保健院 Medicine for treating ovulation failure

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Publication number Priority date Publication date Assignee Title
CN101049397A (en) * 2007-05-16 2007-10-10 北京艺信堂医药研究所 Composition of Chinese traditional medicine for treating barrenness caused by premature ovarian failure
CN103393879A (en) * 2013-07-24 2013-11-20 赵世明 Traditional Chinese medicine composition for treating liver and kidney deficiency
CN104758854A (en) * 2015-04-28 2015-07-08 高纪英 Chinese herba preparation for treating premature ovarian failure
CN105748916A (en) * 2016-04-06 2016-07-13 柳州市妇幼保健院 Medicine for treating ovulation failure

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111632108A (en) * 2020-07-02 2020-09-08 贾锐 Medicine for treating infertility

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