CN101342353A - Traditional Chinese medicine preparation for treating barrenness and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating barrenness and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a Chinese herbal preparation for curing infertility and a preparation method thereof. The Chinese herbal preparation is prepared with 12g of Chinese angelica, 10g of Chinese mugwort leaf, 12g of fructus evodiae, 6g of prepared common monkshood daughter root, 15g of rhizoma corydalis, 12g of rhizoma curcumae longae, 12g of nutgrass galingale rhizome, 12g of common burreed rhizome, 12g of rhizoma zedoariae, 12g of peach kernel, 6g of safflower, 8g of cattail pollen, 12g of trogopterus dung, 15g of medicinal indianmulberry root, 15g of malaytea scurfpea fruit , 20g of motherwort herb, 12g of tortoise shell, 15g of beautiful sweetgum fruit, 12g of turtle shell, 15g of turmeric root-tuber, 12g of cassia barkcassia bark, 12g of red paeony root, 20g of Chinese dodder seed, 12g of Chinese taxillus twig, 12g of Chinese teasel root, 15g of cistanche deserticola, 12g of rehmanniae vaporata, 10g of villous amomum, 15g of common curculigo rhizome, 15g of epimedium herb, 15g of suberect spatholobus stem and 6g of donkey-hide glue. The Chinese herbal preparation, which belongs to a pure Chinese herbal preparation and can be taken by various infertile patients, can regulate the balance between the yin and yang of the human body and the endocrine and exocrine dyscrasias of the human body, so that the menstrual flow and ovulation of patients can return to normal, therefore the chance of conception is greatly increased, and the clinical effect is notable.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of infertility, particularly a kind of is the Chinese medicine preparation and preparation method thereof of the treatment infertility of preparation of raw material with Chinese medicine.
Background technology
After the women of child-bearing age marry, or after the last gestation, the matrimonial cohabitation sexual life is normal, and bridegroom's or husband's side reproductive function is normal, does not practise contraception 2 years and the person of not becoming pregnant is called " infertility ".The former claims " primary infertility ", and the latter claims " secondary infertility ".
The reason of infertility is very complicated, and Mr. and Mrs both sides respectively account for about 50%, and either party descends fertility, all can influence its spouse's fertility.Cause the reason of the female acyesis stagnation of liver-QI of suffering from a deficiency of the kidney, QI and blood deficiency, phlegm-damp, warm qi depression to blood stasis etc.Kidney governing reproduction, collaterals of the uterus be in kidney, kidney person master sting envelope Tibetans in smart part also, be the major reason of infertility so suffer from a deficiency of the kidney, owing to interpromotion and interrestraint between the internal organs meridians, influencing each other and transforming of the heresy of cold-damp expectorant heat has Different types of etiopathogenises clinically, produces different diseases.The pathological changes that these causes of disease cause dashing of kidney to be appointed can not consolidating semen be become pregnant and is caused a disease.In a word, the woman can not have ten (except the female sex organs deformities) by sick son, and uterus is cold, temper is strongly fragrant, taste are cold, the irritability stasis of blood, dai channel urgency, mental disorder Sheng, phase hyperactivity of fire, the kidney pulse decline, times superintend and direct disease, functioning of bladder is unfavorable, asthenia of qi and blood and the change of makings sexually transmitted disease (STD), as endometriosis, hysteromyoma etc., and the ovulatory dysfunction of doctor trained in Western medicine, anovulation, luteal insufficiency, genitals's pathological changes, the factor of cervix uteri, uterus factor, the factor in fallopian tube and abdominal cavity, immune factor, spiritual neural factor, exopathogenic factor factor.
Infertility has the branch of absolute infertility and relative infertility, and absolute infertility is meant defective on woman's congenital or day after tomorrow of dissect physiology, and as four kinds on the contained spiral shell of case in ancient times, stricture of vagina, drum, angle, one says spiral shell: in vaginal orifice profile such as Bellamya quadrata sample screw in; Two say stricture of vagina: vaginal orifice is little big as the chopsticks head, can only lead to, and difficulty is joined, and name is said the woman with a hypoplastic vagina; Three say bulging fresh idea: it is anxious like atresia to stretch tight; Four say the corner piece taper like angle (bright perfectly sound " extensively succeed summary select join ").These infertile surgical operation school shapes that are due to the female reproduction deformity maybe can be proved effective, and real non-traditional Chinese medical science YAOSHI can be helped also.Traditional Chinese medical science institute antisterility is relative infertility, does not promptly have physiological defect, just visceral dysfunction and the infertility that causes.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of infertility and preparation method thereof, it can warm up cold womb by the kidney warming sun, blood circulation promoting and blood stasis dispelling, dredging oviduct, induced ovulation, liver-smoothing, qi-regulating, treatment cold womb type, blood stasis type infertility.
Another purpose of the present invention is to provide a kind of Chinese medicine preparation for the treatment of infertility and preparation method thereof, energy nourishing the liver and kidney, nourishing blood for regulating menstruation, treatment liver-kidney yin deficiency infertility.
A further object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of infertility and preparation method thereof, energy removing dampness clearing away phlegm, clearing away heat-damp and promoting diuresis, treatment stagnation of phlegm-damp in middle-JIAO type infertility.
For this reason, the present invention adopts following solution:
A kind of Chinese medicine preparation for the treatment of infertility is mainly used in cold womb type, blood stasis type infertility, and the component and the consumption of this Chinese medicine preparation are as follows:
Radix Angelicae Sinensis 12 gram Folium Artemisiae Argyis 10 gram Fructus Evodiae 12 gram Radix Aconiti Lateralis Preparatas 6 grams
Rhizoma Corydalis 15 gram Rhizoma Curcumae Longaes 12 gram Rhizoma Cyperis 12 gram rhizoma sparganic 12 grams
Rhizoma Curcumae 12 gram Semen Persicaes 12 gram Flos Carthamis 6 gram Pollen Typhaes 8 grams
Oletum Trogopterori 12 gram Radix Morindae Officinaliss 15 gram Fructus Psoraleaes 15 gram Herba Leonuris 20 grams
Carapax et Plastrum Testudinis 12 gram Fructus Liquidambaris 15 gram Carapax Trionycis 12 gram Radix Curcumaes 15 grams
Parasitic 12 grams of Cortex Cinnamomi 12 gram Radix Paeoniae Rubra 12 gram Semen Cuscutae, 20 grams
Radix Dipsaci 12 gram Herba Cistanchess 15 gram Radix Rehmanniaes Preparata 12 gram Fructus Amomis 10 grams
Rhizoma Curculiginis 15 gram Herba Epimedii 15 gram Caulis Spatholobis 15 gram Colla Corii Asini 6 grams.
A kind of Chinese medicine preparation for the treatment of infertility is mainly used in the liver-kidney yin deficiency infertility, and the component and the consumption of this Chinese medicine preparation are as follows:
Radix Angelicae Sinensis 15 gram Radix Ginsengs 10 Keshan medicines 12 gram Rhizoma Alismatis 12 grams
The Poria 12 gram Radixs Astragali 12 gram Fructus Jujubaes 12 gram Radix Paeoniae Albas 12 grams
The Rhizoma Atractylodis Macrocephalae 12 gram Cortex Moutans 15 gram Radix Curcumaes 12 gram Rhizoma Cyperis 12 grams
Each 12 gram Placenta Hominiss, 6 gram Colla Corii Asini, 10 Keshan taros, 12 gram of two ground
Semen Cuscutae 20 grams
A kind of Chinese medicine preparation for the treatment of infertility is mainly used in stagnation of phlegm-damp in middle-JIAO type infertility, and the component and the consumption of this Chinese medicine preparation are as follows:
Pericarpium Citri Reticulatae 12 cron Radix Gentianae 12 gram Rhizoma Cyperis 12 gram Radix Angelicae Sinensis 15 grams
The Radix Ginseng 10 gram Rhizoma Atractylodis Macrocephalaes 12 gram Rhizoma Atractylodis 12 gram Rhizoma Arisaematis 8 grams
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8 gram Massa Medicata Fermentata 12 gram Herba Lycopi 12 gram JUKE 12 grams
Fructus Forsythiae 12 gram Radix Bupleuri 12 gram Radix Paeoniae Rubra 12 gram Semen Persicaes 12 grams
Flos Carthami 6 gram Semen Cuscutae 20 grams
A kind of preparation method of making the Chinese medicine preparation of above-mentioned treatment infertility, it makes powder, and making step is: earlier be equipped with medicine by the Chinese herbal medicine of respectively distinguishing the flavor of in the prescription, through screening, high-temperature sterilization, dry, be ground into fine-powdered, again according to the ratio of medicine of respectively distinguishing the flavor of in the prescription, pack after getting the powder mix homogeneously respectively.
A kind of preparation method of making the Chinese medicine preparation of above-mentioned treatment infertility, it makes pill, making step is: be equipped with medicine by the Chinese herbal medicine of respectively distinguishing the flavor of in the prescription earlier, through screening, high-temperature sterilization, dry, be ground into fine-powdered, again according to the ratio of medicine of respectively distinguishing the flavor of in the prescription, get respectively and beat ball behind the powder mix homogeneously, polishing is packed at last.
The invention belongs to pure Chinese medicinal preparation, be applicable to that all types of infertility patients takes, can regulate the equilibrium between yin and yang and the inside and outside dyssecretosis of human body, after orally using 1-2 the course of treatment, make patient's eumenorrhea, ovulation is normal, thereby pregnancy chance improves greatly, clinical efficacy is remarkable, total effective rate reaches 83%, and its processing technology of Chinese medicine preparation of the present invention is simple, patient's taking convenience, have no side effect, praised by extensive patients.
The specific embodiment
The total clinical manifestation of infertility has its general character, as menoxenia, dysmenorrhea, amenorrhea, distending pain of the breast, aching pain in waist and back etc., be clinically to stress difference and with, Chinese traditional treatment female infertility, dialectical from ancient times to the present a lot of, be relative infertility from traditional Chinese medical science institute antisterility.Promptly there is not physiological defect, and visceral dysfunction the and no matter infertility that causes the sort of situation or multiple syndrome occur, but from modal clinically, it is reduced the three major types type just:
One, cold womb type, blood stasis type
Etiology and pathogenesis: seven emotions, depressed emotion, qi depression to blood stasis or the resistance of the exopathogen invasion cold coagulation stasis of blood due to wound.
Uterus because the deficiency of kidney yin decline of the fire from the gate of life is dashed to appoint and lost in warm or following no deficiency and coldness, causes infertility for breeding the place of fetus.
Clinical manifestation: menoxenia or dysmenorrhea, coldness of the body with chills, the cold frequent micturition of few abdomen loose stool, light red tongue is fat, and tongue is white, deep-slow pulse or menoxenia, amount is few not smooth or dripping unclean, and menses are purple black, and there is ecchymosis on the dim limit of body of the tongue, and stringy pulse is heavy.
The Therapeutic Principle: the warm cold womb of the kidney warming sun, blood circulation promoting and blood stasis dispelling, liver-smoothing, qi-regulating, the pregnant son of medication title looses I number.
Prescription: Radix Angelicae Sinensis 12 grams, Folium Artemisiae Argyi 10 grams, Fructus Evodiae 12 grams, Radix Aconiti Lateralis Preparata 6 grams, Rhizoma Corydalis 15 grams, Rhizoma Curcumae Longae 12 grams, Rhizoma Cyperi 12 grams, rhizoma sparganic 12 grams, Rhizoma Curcumae 12 grams, Semen Persicae 12 grams, Flos Carthami 6 grams, Pollen Typhae 8 grams, Oletum Trogopterori 12 grams, Radix Morindae Officinalis 15 grams, Fructus Psoraleae 15 grams, Herba Leonuri 20 grams, Carapax et Plastrum Testudinis 12 grams, Fructus Liquidambaris 15 grams, Carapax Trionycis 12 grams, Radix Curcumae 15 grams, Cortex Cinnamomi 12 grams, Radix Paeoniae Rubra 12 grams, Semen Cuscutae 20 grams, parasitic 12 grams, Radix Dipsaci 12 grams, Herba Cistanches 15 grams, Radix Rehmanniae Preparata 12 grams, Fructus Amomi 10 grams, Rhizoma Curculiginis 15 grams, Herba Epimedii 15 grams, Caulis Spatholobi 15 grams, Colla Corii Asini 6 grams.Obey each 9 grams every day three times.
Two, liver-kidney yin deficiency
Etiology and pathogenesis: conception vessel lies in kidney, kidney storing essence master born of the same parents tire, innate deficiency or kidney yang secretly consumes, moist, Chong and Ren channel disorder is lost in sperm loss, born of the same parents and cause infertile, the woman is this with blood, dash to appoint and be subordinate to, liver storing blood, department's sea of blood in liver, deficiency of liver-blood dash to appoint lose is supported and is caused infertile, deficiency of yang of liver and kidney is person or see hyperactivity of fire caused by deficiency of YIN very, sea of blood intrinsic heat, accumulation of heat in CHONG and REN meridians, and uterus can not be become pregnant by consolidating semen.
Clinical manifestation: menoxenia is successively indefinite, the few light or amenorrhea of color of amount, and aching pain in waist and back is had a dizzy spell, dryness of the mouth and throat, dysphoria with feverish sensation in the chest palms and soles, shortness of breath and palpitation, insomnia forgetfulness, spiritlessness and weakness, pale tongue with white fur etc.
The Therapeutic Principle: nourishing the liver and kidney, nourishing blood for regulating menstruation, the pregnant son of medication title looses II number.
Prescription: Radix Angelicae Sinensis 15 grams, Radix Ginseng 10 grams, Rhizoma Dioscoreae 12 grams, Rhizoma Alismatis 12 grams, Poria 12 grams, the Radix Astragali 12 grams, Fructus Jujubae 12 grams, the Radix Paeoniae Alba 12 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Cortex Moutan 15 grams, Radix Curcumae 12 grams, Rhizoma Cyperi 12 grams, each 12 gram of two ground, Placenta Hominis 6 grams, Colla Corii Asini 10 grams, Rhizoma Dioscoreae 12 grams, Semen Cuscutae 20 grams.
Three, stagnation of phlegm-damp in middle-JIAO type:
Etiology and pathogenesis: the easy impairment of YANG gas of damp being a kind of YIN pathogen, damp pathogen obstructing the spleen, spleen sun are subjected to press down, and water Tianjin is cloth not, accumulate the living expectorant of cloth, or the disturbance in functioning of QI of suffering from a deficiency of the kidney, and giving birth in the phlegm-damp stagnates appoints heap soil or fertilizer over and around the roots resistance uterus not become pregnant in dashing.With the passing of time damp accumulates and heat-transformation, and the uterus that is jammed also can cause and can not become pregnant by consolidating semen.
Clinical symptoms: menoxenia, very then amenorrhea, obesity, breast is indigestion and loss of appetite, and body is tired drowsiness.Leucorrhoea grow in quantity, light red tongue is fat, and soft pulse is slided, and menostaxis then appears in the with the passing of time biochemical heat of damp, the leucorrhea with red and white discharge lumbosacral aching pain, day food in one's mouth hectic fever, few abdomen bob is bloated etc.
The Therapeutic Principle: the removing dampness clearing away phlegm, clearing away heat-damp and promoting diuresis, the pregnant son of medication title looses III number.
Prescription: Pericarpium Citri Reticulatae 12 grams, Radix Gentianae 12 grams, Rhizoma Cyperi 12 grams, Radix Angelicae Sinensis 15 grams, Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Rhizoma Atractylodis 12 grams, Rhizoma Arisaematis 8 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8 grams, Massa Medicata Fermentata 12 grams, Herba Lycopi's 12 grams, JUKE 12 grams, Fructus Forsythiae 12 grams, Radix Bupleuri 12 grams, Radix Paeoniae Rubra 12 grams, Semen Persicae 12 grams, Flos Carthami 6 grams, Semen Cuscutae 20 grams.
So " pregnant son loose " also is divided into I number, II number, III number in treatment, three kinds can be suitable for (remove Radix Ginseng when share, because of Radix Ginseng opposite with Oletum Trogopterori) altogether, and 3 also can separately be used, therapeutic effect is also arranged.
It can be made into powder the Chinese medicine preparation of above-mentioned treatment infertility, making step is: be equipped with medicine by the Chinese herbal medicine of respectively distinguishing the flavor of in the prescription earlier, through screening, high-temperature sterilization, dry, be ground into fine-powdered, again according to the ratio of medicine of respectively distinguishing the flavor of in the prescription, pack after getting the powder mix homogeneously respectively.
It can be made into pill the Chinese medicine preparation of same treatment infertility, making step is: be equipped with medicine by the Chinese herbal medicine of respectively distinguishing the flavor of in the prescription earlier, through screening, high-temperature sterilization, dry, be ground into fine-powdered, again according to the ratio of medicine of respectively distinguishing the flavor of in the prescription, get respectively and beat ball behind the powder mix homogeneously, polishing is packed at last.
The traditional Chinese medical science is valued for dialectical, and the Chinese medicine preparation that the present invention treats infertility must be grasped its characteristics in clinical treatment, pay attention to dialectical executing and control, and applies in a flexible way, and every side is the medicine of liver-smoothing, qi-regulating regulating qi to disperse stagnation in addition.Because the woman generally is good at anger, and grasp dosage according to body constitution, so good effect, safety finally reaches therapeutic purposes.
Model case:
1, Lee's meter, woman, 30 years old, native left bannerman, phone: 8430164
The patient is menoxenia always after marriage, dysmenorrhea, and amount is few, and color is black dull, and piece is not freely arranged, soreness of waist and knee joint, extremity are not warm, the hypochondriac pain mammary swelling, light red tongue is fat, and tongue is white, and petechia is arranged, deep-slow pulse, string is puckery.
2, Zhou Zhihua, the woman 28 years old, reports the township to report the village ingeniously, phone after exhaling the city: 688116513847110771 ingeniously
The patient married in 21 years old, menoxenia always after marriage, and amount is rare, and color is light, plain body weakness, lusterless complexion, dizziness, body is weary unable, and cardiopalmus is weak, insomnia forgetfulness, dysphoria with feverish sensation in the chest palms and soles, pale tongue with white fur, thready and soft pulse.
Differential diagnosis in tcm is: liver-kidney yin deficiency.Oral pregnant son looses II number, patient's pregnancy after four months.
3, Liang Siqin, woman, 26 years old, the work of 5303 factories.
The patient married in 20 years old, menoxenia after marriage even amenorrhea, and fat abundant expectoration, drowsiness weak, enlarged tongue is light, and tongue is greasy in vain, and soft pulse is sliding.
Differential diagnosis in tcm: stagnation of phlegm-damp in middle-JIAO type, oral pregnant son loose conceived after III number four months.
Below be the clinical research of the diffusing treatment of the pregnant son of utilization 388 routine female infertilities:
388 routine infertility are minimal ages 21 years old wherein, maximum 42 years old age, primary infertility 286 examples are arranged, insecondary 108 examples, what case was the longest has 19 years, the shortest 2 years.Infertile reason, 267 examples of menoxenia, 54 examples of gynecological inflammation, 65 examples of tubal occlusion, 1 example of other reason.
Below only supply explanation the present invention's usefulness, but not the restriction to inventing, person skilled in the relevant technique under the situation that does not break away from the spirit and scope of the present invention, can also be made various conversion or variation.Therefore, all technical schemes that are equal to also should belong to category of the present invention, should be limited by each claim.
Claims (5)
1, a kind of Chinese medicine preparation for the treatment of infertility is characterized in that: the component and the consumption of this Chinese medicine preparation are as follows:
Radix Angelicae Sinensis 12 gram Folium Artemisiae Argyis 10 gram Fructus Evodiae 12 gram Radix Aconiti Lateralis Preparatas 6 grams
Rhizoma Corydalis 15 gram Rhizoma Curcumae Longaes 12 gram Rhizoma Cyperis 12 gram rhizoma sparganic 12 grams
Rhizoma Curcumae 12 gram Semen Persicaes 12 gram Flos Carthamis 6 gram Pollen Typhaes 8 grams
Oletum Trogopterori 12 gram Radix Morindae Officinaliss 15 gram Fructus Psoraleaes 15 gram Herba Leonuris 20 grams
Carapax et Plastrum Testudinis 12 gram Fructus Liquidambaris 15 gram Carapax Trionycis 12 gram Radix Curcumaes 15 grams
Parasitic 12 grams of Cortex Cinnamomi 12 gram Radix Paeoniae Rubra 12 gram Semen Cuscutae, 20 grams
Radix Dipsaci 12 gram Herba Cistanchess 15 gram Radix Rehmanniaes Preparata 12 gram Fructus Amomis 10 grams
Rhizoma Curculiginis 15 gram Herba Epimedii 15 gram Caulis Spatholobis 15 gram Colla Corii Asini 6 grams.
2, a kind of Chinese medicine preparation for the treatment of infertility is characterized in that: the component and the consumption of this Chinese medicine medicine preparation are as follows:
Radix Angelicae Sinensis 15 gram Radix Ginsengs 10 Keshan medicines 12 gram Rhizoma Alismatis 12 grams
The Poria 12 gram Radixs Astragali 12 gram Fructus Jujubaes 12 gram Radix Paeoniae Albas 12 grams
The Rhizoma Atractylodis Macrocephalae 12 gram Cortex Moutans 15 gram Radix Curcumaes 12 gram Rhizoma Cyperis 12 grams
Each 12 gram Placenta Hominiss, 6 gram Colla Corii Asini, 10 Keshan taros, 12 gram of two ground
Semen Cuscutae 20 grams.
3, a kind of Chinese medicine preparation for the treatment of infertility is characterized in that: the component and the consumption of this Chinese medicine medicine preparation are as follows:
Pericarpium Citri Reticulatae 12 cron Radix Gentianae 12 gram Rhizoma Cyperis 12 gram Radix Angelicae Sinensis 15 grams
The Radix Ginseng 10 gram Rhizoma Atractylodis Macrocephalaes 12 gram Rhizoma Atractylodis 12 gram Rhizoma Arisaematis 8 grams
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8 gram Massa Medicata Fermentata 12 gram Herba Lycopi 12 gram JUKE 12 grams
Fructus Forsythiae 12 gram Radix Bupleuri 12 gram Radix Paeoniae Rubra 12 gram Semen Persicaes 12 grams
Flos Carthami 6 gram Semen Cuscutae 20 grams.
4, a kind of preparation method for preparing the Chinese medicine preparation of claim 1 or 2 or 3 described treatment infertility, it is characterized in that: be made into powder, its making step is: be equipped with medicine by the Chinese herbal medicine of respectively distinguishing the flavor of in the prescription earlier, through screening, high-temperature sterilization, dry, be ground into fine-powdered, again according to the ratio of medicine of respectively distinguishing the flavor of in the prescription, pack after getting the powder mix homogeneously respectively.
5, a kind of preparation method for preparing the Chinese medicine preparation of claim 1 or 2 or 3 described treatment infertility, it is characterized in that: be made into pill, its making step is: be equipped with medicine by the Chinese herbal medicine of respectively distinguishing the flavor of in the prescription earlier, through screening, high-temperature sterilization, dry, be ground into fine-powdered, again according to the ratio of medicine of respectively distinguishing the flavor of in the prescription, get respectively and beat ball behind the powder mix homogeneously, polishing is packed at last.
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