CN109908007A - A kind of composition of the anti-sensitivity of tooth containing magnesium salts and its application - Google Patents

Abstract

The composition of the invention discloses a kind of anti-sensitivity of tooth containing magnesium salts, consists of the following components in percentage by mass: magnesium salts 0.01%~3%, magnesium salts anion provide agent 0.01%~0.8%；Tooth powder containing the composition, the mass percent that the composition accounts for entire tooth powder is 0.02%~3.8%；The mass percent that green tea accounts for entire tooth powder is 1%~40%；The mass percent that tea polyphenols account for entire tooth powder is 0.1%~40%；Also disclose the preparation method of the composition and the tooth powder containing the composition；The composition and its tooth powder of the invention has anti-sensitivity of tooth effect.

Description

A kind of composition of the anti-sensitivity of tooth containing magnesium salts and its application

Technical field

The composition and its tooth powder of the present invention relates to a kind of oral care product that can resist sensitivity of tooth containing magnesium salts and Preparation method belongs to oral care implement field.

Background technique

Sensitivity of tooth, also known as dentine hypersensitivity, are called dental hypersensitiveness, resident with advancing age, due to each Kind factor leads to the symptoms such as acid etching, enamel abrasion, wedge-shaped defect, gingival atrophy, when tooth encounters the cold and hot sour-sweet equal or external world When stimulation, cause of short duration and sharp discomfort or pain, it is serious to show as the aching and limp inability of tooth.

Dentine exposure and open tubules are the major reasons for generating dentine hypersensitivity.

The nearly dental pulp one end of dentinal tubule is thicker, and diameter is about 2.5 μm, more thinner to surface;It is about 1 μ near surface M, and arrange sparse.Dentine the ratio between tubule number in nearly marrow end and near surface per unit area is about 4:1, dentinal tubule Surface is stretched to from dental pulp end, separates many collateral, and the collateral matches mutually with neighbouring tubule on the way.

It is at present generally to use the substance of strontium salt, that is, strontium chloride and sylvite such as potassium nitrate as anti-sensitivity of tooth.

Toothpaste with fluoride is widely used in China and in the world, and fluoride is well known anti-caries agent.

Fluorine ion can promote remineralization of teeth.

Tealeaves especially green tea contains tea polyphenols, and refreshing and detoxicating, some researches show that tea polyphenols can alleviate oral inflammation, right The effect that gum reparation has.

In the patent document of 101123939 A of publication number CN, it is described below content: oral care composition, including xylose Pure and mild water-soluble calcium salt, wherein the big xylitol and the calcium salt exist with the weight ratio of at least about 10:1.It is solvable Be selected from the calcium salt of water: calcium chloride, calcium acetate, calcium butyrate, calcium citrate, calcium lactate, calcium salicylate, calcium glycerophosphate and its Mixture.Agent is provided including fluoride, wherein it is sodium monofluorophosphate that the fluoride, which provides agent,.Wherein the fluoride provides agent Existing amount is enough to provide about 200ppm to 3000ppm fluoride ion, and the fluoride provides agent with about 0.001% to about 3% Weight is present in the composition.

" oral health blue book " P128-132, " the B.12 method of clinic control dentine hypersensitivity ".

The 2nd phase of volume 23 " dentistry research " in April, 2007, " experiment of tricalcium silicate obstruction dentinal tubule was ground Study carefully " (key lab, Jilin University's School of Stomatology oral cavity biomedical engineering Jilin Province Wang Xiao rainbow etc.) be described below content: Abstract purpose: block capability of the evaluation tricalcium silicate to dentinal tubule.Conclusion: tricalcium silicate not only passes through self-curing process Block dentinal tubule, and can induce dentine remineralization under physiological environment.Therefore, it is contemplated that be used as treatment dentine mistake Quick active drug.

" Shanghai Second Emdical University's journal " Vol.19 No.1 1999, " tea polyphenols act on oral cavity and throat pathogenic bacteria Experiment in vitro " in (No.9 People's Hospital Attached to Shanghai No.2 Medical Univ Dental Research Institute Liu Li Mingyu is just) be described below Hold: abstract purpose: a possibility that evaluation tea polyphenols are as oral health medication.As a result: tea polyphenols are to oral cavity and throat principal causative Bacterium is sensitive, and synthesizing glucan ability and people's salivary amylase activity to cariogenic bacteria has inhibition.

" Practical oral medical journal " (J P ract Stom a to l) 2007 Jul, 23 (4)) " green tea polyphenols are to tooth The inhibiting effect of inflammatory factor in gingival epithelial cells " (hat educates flourish Pan Yaping) be described below content: abstract purpose: inquire into green tea The effect of nutgall catechin and gallate (EGCg) to the inflammatory reaction of human gingival epithelial cells in polyphenol.To be periodontal Safely and effectively periodontal disease inhibitor provides foundation for the prevention and treatment exploitation of disease.Conclusion: (EGCg) is to human gingival epithelial cells Inflammatory reaction it is inhibited, have as periodontal disease inhibitor potential.

A kind of dentinal tubule that can block opening containing magnesium salts is researched and developed, to be resistant to the oral-cavity article of sensitivity of tooth.

Summary of the invention

It is an object of the present invention to provide a kind of composition with anti-sensitivity of tooth and its tooth powder and preparation methods.

The present invention realizes its purpose technical solution.

Using one or more slightly solubles or it is insoluble in the particle of water, size is sufficiently small, and it is small to can enter open dentine Pipe, blocks open dentinal tubule, achievees the purpose that anti-sensitivity of tooth.The size of molecule and micel is with regard to sufficiently small, in model It can enter open dentinal tubule under the effect of moral China power, block open dentinal tubule.It can choose and have this characteristic Slightly soluble or be insoluble in molecule and micel of the magnesium salts if any magnesium fluoride, magnesium phosphate and magnesium carbonate etc. of water.

A kind of composition with anti-sensitivity of tooth provides agent by magnesium salts and magnesium salts anion and forms.In aqueous solution or saliva In liquid, magnesium salts discharges magnesium ion, and magnesium salts anion provides agent and discharges anion such as fluorine ion, in the oral cavity magnesium ion and fluorine ion The magnesium fluoride molecule and micel for being insoluble in water are generated, the molecule and micel enter open dentinal tubule, block and open Dentinal tubule, achieve the purpose that anti-sensitivity of tooth.

Based on the above-mentioned technical proposal, a kind of composition with anti-sensitivity of tooth, the constituent mass hundred of the composition are invented Divide ratio to be: magnesium salts 0.01%~3%, magnesium salts anion provide agent 0.01%~0.8%.

Magnesium salts.

Water-soluble magnesium salts is soluble and remains soluble in water or saliva and discharges magnesium ion, and suitable magnesium salts includes inorganic Magnesium salts and organic magnesium salts and its mixture.

Inorganic magnesium salt include magnesium nitrite, magnesium nitrate, magnesium sulfate, magnesium sulfite, magnesium thiosulfate, magnesium bromide, magnesium iodide, Magnesium hypochlorite, magron, magnesium perchlorate, hypobromous acid magnesium, magnesium bromate, hyperbromic acid magnesium, hypoiodous acid magnesium, magnesium iodate, periodic acid magnesium, sulphur Cyanic acid magnesium, magnesium bicarbonate, magnesium dihydrogen phosphate, magnesium monohydrogen phosphate, phosphorous acid magnesium, magnesium hypophosphite, magnesium fluosilicate, fluoboric acid magnesium, wolframic acid Magnesium and its mixture.

Organic magnesium salts include magnesium formate, magnesium acetate, propionic acid magnesium, α-hydracrylate magnesium, 2 Ethylbutanoic acid magnesium, magnesium octoate, lemon Lemon acid magnesium, magnesium lactate, Pfansteihl magnesium, magnesium salicylate, magnesium glycerophosphate, magnesium gluconate, Magnesium ascorbate, magnesium benzoate, junket Protein acid magnesium, magnesium lignosulfonate, bis- psicosoma of L-, magnesium fumarate, Magnesium dilaurate, phytic acid magnesium, 3-hydroxybutyrate magnesium, propylene Sour magnesium, magnesinm methacrylate, magnesium glycinate, L- lucid asparagus amino acid-magnesium chelate, pyruvic acid magnesium, thioacetic acid magnesium, magnesium malate, winestone Sour magnesium, 2,5- dihydroxy benzenes sulfonic acid magnesium, 3-hydroxybutyrate magnesium, L- magnesium threonate, magnesium triflate and its mixture.

Preferably, water-soluble magnesium salts is soluble and remains soluble in water or saliva, and the preferred magnesium salts is Inorganic magnesium salt, preferred inorganic magnesium salt are magnesium sulfate, and magnesium sulfate mass percent is 0.01%~3%.

Preferably, magnesium sulfate mass percent is 0.5%~1.5%.

Magnesium salts anion provides agent.

Magnesium salts anion, which provides agent, has enough water solubilitys to discharge anion or anionic group in water or saliva, Anion or anionic group and magnesium ion generate slightly soluble or are insoluble in the compound of water.Suitable magnesium salts anion provides agent packet Fluoride is included agent, phosphate, phosphite, metaphosphate, carbonate, tungstates, borate, acylate are provided and its mixed Close object.

Fluoride provides agent.

Fluoride, which provides agent, has enough water solubilitys to discharge fluoride anion in water or saliva.Suitable fluorination Object provides agent and provides agent for inorganic fluoride.

It includes fluoride salt, mono-fluor phosphate, difluorophosphoric acid salt and hexafluorophosphate, including fluorination that inorganic fluoride, which provides agent, Ammonium, lithium fluoride, sodium fluoride, potassium fluoride, rubidium fluoride RbF, cesium fluoride, stannous fluoride, single fluorophosphoric acid ammonium, single lithium fluophosphate, single fluorophosphoric acid Sodium, single fluorophosphoric acid potassium, single fluorophosphoric acid rubidium, single fluorophosphoric acid caesium, difluorophosphoric acid ammonium, difluorophosphate, difluorophosphoric acid sodium, difluorophosphoric acid Potassium, difluorophosphoric acid rubidium, difluorophosphoric acid caesium, ammonium hexafluorophosphate, lithium hexafluoro phosphate, sodium hexafluoro phosphate, Potassium Hexafluorophosphate, hexafluorophosphoric acid Rubidium, hexafluorophosphoric acid caesium and its mixture.

Phosphate.

Phosphate has enough water-soluble to discharge phosphate anion or one hydrogen radical ion of phosphoric acid in water or saliva.It is suitable Suitable phosphate includes ammonium phosphate, lithium phosphate, sodium phosphate, potassium phosphate, phosphoric acid rubidium, phosphoric acid caesium, magnesium phosphate, monoammonium phosphate, phosphorus A sour hydrogen lithium, disodium-hydrogen, potassium phosphate,monobasic, one hydrogen rubidium of phosphoric acid, one hydrogen caesium of phosphoric acid and its mixture.

Phosphite.

Phosphite has enough water solubilitys to discharge orthophosphite ions in water or saliva.Suitable phosphite Including ammonium phosphite, sodium phosphite, potassium phosphite, phosphorous acid rubidium, phosphorous acid caesium and its mixture.

Metaphosphate.

Metaphosphate has enough water solubilitys to discharge metaphosphate ion in water or saliva.Suitable phosphite Including ammonium metaphosphate, sodium metaphosphate, potassium metaphosphate, metaphosphoric acid rubidium, metaphosphoric acid caesium and its mixture.

Carbonate.

Carbonate has enough water solubilitys to discharge carbanion in water or saliva.Suitable carbonate includes carbon Sour lithium, sodium carbonate, potassium carbonate, rubidium carbonate, cesium carbonate, ammonium carbonate and its mixture.

Tungstates.

Tungstates has enough water solubilitys to discharge tungstate ion in water or saliva, and suitable tungstates includes tungsten Sour ammonium, tungstate lithium, sodium tungstate, potassium tungstate, wolframic acid rubidium, wolframic acid caesium and its mixture.

Borate.

Borate has enough water solubilitys to discharge borate ion in water or saliva, and suitable borate includes boron Sour ammonium, lithium borate, Boratex, potassium borate, boric acid rubidium, boric acid caesium and its mixture.

Acylate.

Acylate has enough water solubilitys to discharge organic acid anions or anionic group in water or saliva, has Machine hydrochlorate include unary fatty acid salt, di-fatty hydrochlorate, alkyl sulfate, alkylphosphonic, amino-acid salt, sulfonate and Its mixture.

Unary fatty acid salt includes its ammonium salt, lithium salts, sodium salt and sylvite, alkyl carbon chain C_9-20Range, such as ammonium laurate, the moon Cinnamic acid lithium, sodium laurate, potassium laurate, palmitic acid ammonium, sodium palmitate, palmitic acid potassium, ammonium stearate, lithium stearate, stearic acid Sodium, potassium stearate and its mixture.

Di-fatty hydrochlorate includes ammonium oxalate, lithium oxalate, sodium oxalate, potassium oxalate, malonic acid ammonium, Lithium malonate, malonic acid Sodium, malonic acid potassium, ammonium succinate, succinic acid lithium, sodium succinate, potassium succinate, glutaric acid ammonium, glutaric acid lithium, Sodium glutarate, penta Diacid potassium, ammonium adipate, lithium adipate, adipic acid sodium, Potassium Adipate, ammonium tartrate, ammonium tartrate, lithium tartrate, tartaric acid Sodium, potassium tartrate and its mixture.

Alkyl sulfate includes its ammonium salt, lithium salts, sodium salt and sylvite, alkyl carbon chain C_12-18Range, such as dodecyl sulphate Ammonium, lithium dodecyl sulfate, lauryl sodium sulfate, dodecyl sulphate potassium, n-hexadecyl sodium sulphate, n-octadecane base sulphur Sour sodium and its mixture.

Alkylphosphonic includes its ammonium salt, lithium salts, sodium salt and sylvite, alkyl carbon chain C_12-18Range, such as dodecylphosphoric acid Ammonium, dodecylphosphoric acid lithium, ferric tri-dodecanesulfonate, Potassium dodecyl phosphate, n-hexadecyl sodium phosphate, n-octadecane base phosphorus Sour sodium and its mixture.

Amino-acid salt includes sodium lauroyl sarcosine, potassium lauroyl sarcosine, sodium lauroyl glutamate, lauroyl glutamate Potassium, cocoyl Sodium Glycinate, cocoyl glycine potassium, cocoyl Sodium L-alaninate, sodium dodecyl aminopropionitrile, Pork and beans Guan acyl sodium glutamate, palmityl sodium glutamate, stearoyl-glutamic acid sodium and its mixture.

Sulfonate includes ammonium salt, lithium salts, sodium salt and the sylvite of alkylsulfonate, alkyl carbon chain C_12-20Range, such as dodecane Base ichthyodin, dodecyl sodium sulfonate lithium, dodecyl sodium sulfate, potassium dodecanesulfonate, there are also dioctyl sodium sulfosuccinate, Neopelex, nekal and its mixture.

Preferably, water-soluble magnesium salts anion offer agent is soluble and remains soluble in water or saliva, preferably The magnesium salts anion to provide agent be that fluoride provides agent, it is sodium fluoride, mass percent that preferred fluoride, which provides agent, It is 0.01%~0.8%.

Preferably, sodium fluoride mass percent is 0.1%~0.4%.

Preferably, a kind of mass percent of the composition with anti-sensitivity of tooth is 0.6%~1.9%, by as follows The group of mass percent is grouped as: magnesium sulfate 0.5%~1.5%, sodium fluoride 0.1%~0.4%.

A kind of application of above-mentioned composition in tooth powder.

Application of the composition in tooth powder, preferably, the mass percent that the composition accounts for whole components is 0.6%~1.9%.

A kind of tooth powder with anti-sensitivity of tooth, comprising rubbing agent, sweetener, tea polyphenols, also include the above technical side Composition described in case, mass percent of the composition in tooth powder are 0.02%~3.8%, preferably 0.6%~1.9%.

Mass percent of the tea polyphenols in tooth powder is 0.1%~40%, preferably 1%~20%.

A kind of tooth powder with anti-sensitivity of tooth, comprising rubbing agent, sweetener, tealeaves, also include above technical scheme The composition, mass percent of the composition in tooth powder are 0.02%~3.8%, preferably 0.6%~1.9%.

The tealeaves is black tea, green tea, Partial fermentation tea, preferably green tea, and the mass percent in tooth powder is 1% ~40%, preferably 5%~20%.

The composition is applied in mouthwass, collutory, mouthwash, the agent of liquid tooth, the agent of solid tooth, tooth film, gear rack, gel Application in agent, tooth bead, pastille, toothpaste, tooth gel and tooth latex, including mouthwass, collutory, mouthwash, The agent of liquid tooth, the agent of solid tooth, tooth film, gear rack, gel paint, tooth bead, pastille, toothpaste, tooth gel and tooth latex etc. exist It can be single-item before into oral cavity and be also possible to combined article.The composition account for whole components mass percent be 0.02%~ 3.8%。

A kind of preparation method of above-mentioned tooth powder includes the following steps: green tea, rubbing agent, sweetener, also includes anti-tooth Sensitive composition, is respectively prepared powder, and the component by every kind of content no more than 10% is first uniformly mixed in a reservoir, so Remaining component is put into the container afterwards to be stirred for being uniformly mixed and obtains mixture, is sieved, screenings is finished product tooth powder, tooth Powder preparation is completed.

A kind of preparation method of above-mentioned tooth powder includes the following steps: tea polyphenols, rubbing agent, sweetener, also includes anti-tooth The composition of tooth sensitivity, is respectively prepared powder, and the component by every kind of content no more than 10% is first uniformly mixed in a reservoir, Then remaining component being put into the container to be stirred for being uniformly mixed and obtains mixture, be sieved, screenings is finished product tooth powder, Tooth powder preparation is completed.

The beneficial effects of the present invention are: the composition of the anti-sensitivity of tooth for oral care of the invention, can block Open dentinal tubule plays the role of alleviating sensitivity of tooth pain, achievees the effect that anti-sensitivity of tooth, then including the group It closes and tea polyphenols or green tea is added in the tooth powder of object, play the role of alleviating gum discomfort, reduce oral peculiar smell.

Specific embodiment

Below with reference to embodiment, the invention will be further described, but not thereby limiting the invention.

Experimental method in following embodiments is unless otherwise instructed conventional method.

Embodiment 1 has the composition of anti-sensitivity of tooth.

Embodiment 1 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 0.01% ~3%, sodium fluoride 0.01%~0.8%.

Embodiment 2 has the composition of anti-sensitivity of tooth.

Embodiment 2 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 0.01%, Sodium fluoride 0.01%.

Embodiment 3 has the composition of anti-sensitivity of tooth.

Embodiment 3 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 0.5%~ 1%, sodium fluoride 0.1%~0.2%.

Embodiment 4 has the composition of anti-sensitivity of tooth.

Embodiment 4 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 1.2%, Sodium fluoride 0.32%.

Embodiment 5 has the composition of anti-sensitivity of tooth.

Embodiment 5 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 1%~ 1.5%, sodium fluoride 0.2%~0.4%.

Embodiment 6 has the composition of anti-sensitivity of tooth.

Embodiment 6 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 1.5%~ 2.5%, sodium fluoride 0.5%~0.7%.

Embodiment 7 has the composition of anti-sensitivity of tooth.

Embodiment 7 has the composition of anti-sensitivity of tooth, consists of the following components in percentage by mass: magnesium sulfate 3%, fluorine Change sodium 0.8%.

Embodiment 8 has the tooth powder of anti-sensitivity of tooth.

Embodiment 8 prepares tooth powder in accordance with the following steps: granularity is made not less than 325 mesh powder, by rubbing agent system in green tea It is not less than 1000 mesh powder at granularity, the combination of anti-sensitivity of tooth described in any one embodiment in sweetener, embodiment 1-7 Granularity is respectively prepared not less than 100 mesh powders in object, and the component by every kind of content no more than 10% is first stirred in a reservoir It is even, then remaining component is put into the container be stirred for be uniformly mixed obtain mixture, mixture sieves with 100 mesh sieve, under sieve Object is finished product tooth powder, and tooth powder preparation is completed.

Embodiment 9 has the tooth powder of anti-sensitivity of tooth.

Embodiment 9 prepares tooth powder in accordance with the following steps: granularity is made not less than 1000 mesh powder in rubbing agent, tea polyphenols, Granularity is respectively prepared not less than 100 in the composition of anti-sensitivity of tooth described in any one embodiment in sweetener, embodiment 1-7 Mesh powder, the component by every kind of content no more than 10% are first uniformly mixed in a reservoir, then remaining component are put into It is stirred for being uniformly mixed in the container and obtains mixture, mixture sieves with 100 mesh sieve, and screenings is finished product tooth powder, tooth powder preparation It completes.

The mass percent of each component described in embodiment 8-9.

The composition 0.02%~3.8% of the anti-sensitivity of tooth, preferably 0.6%~1.9%.

The rubbing agent 70%~98%, preferably 80%~93%, silica, calcium monohydrogen phosphate, calcium carbonate can be used Deng.

The sweetener 0.1%~5%, preferably 0.5%~2%, neotame, Abbas's sweet tea, saccharin sodium etc. can be used.

Green tea 1%~40%, preferably 5%~20% described in embodiment 8.

Tea polyphenols 0.1%~40%, preferably 1%~20% described in embodiment 9.

Embodiment 10 contains the tooth powder measure of merit of anti-sensitivity of tooth composition.

The tooth powder of composition of the preparation containing anti-sensitivity of tooth, the constituent mass percentage of the tooth powder is calcium carbonate respectively 82.98%, green tea 15%, magnesium sulfate 1.2%, saccharin sodium 0.5%, sodium fluoride 0.32%.Sensitivity of tooth patient using before the tooth powder, Usually feel that suffering from tooth is afraid of acid, after first being brushed teeth with toothpaste, tooth powder is gently applied on the tooth and gum of full mouth, is generated to oral cavity Saliva, with salivary rinse 3~7 minutes, once in the morning and once at night, and 1~1.5 gram of each dosage, after the 10 day time of the tooth powder, Do not feel that suffering from the feeling that tooth has acid feels to suffer from tooth also when slightly firmly scraping the exterior of teeth for suffering from the nearly tooth root of tooth with nail A little sour, breath freshening, using one month future trouble tooth of the tooth powder, sour feeling is not suffered from after the tooth powder three months Tooth not sour feeling when slightly firmly scraping the exterior of teeth for suffering from the nearly tooth root of tooth with nail, feels that tooth is not sour.Tooth powder tool There is the effect of anti-sensitivity of tooth.

Embodiment 11 contains the tooth powder measure of merit of anti-sensitivity of tooth composition.

The tooth powder of composition of the preparation containing anti-sensitivity of tooth, the constituent mass percentage of the tooth powder is calcium carbonate respectively 87.98%, tea polyphenols 10%, magnesium sulfate 1.2%, saccharin sodium 0.5%, sodium fluoride 0.32%.Sensitivity of tooth patient suffer from tooth be afraid of acid with Implication when slightly firmly scraping the exterior of teeth for suffering from the nearly tooth root of tooth with nail, feels tooth acid, after first being brushed teeth with toothpaste, by tooth Powder is gently applied on the tooth and gum of full mouth, generates saliva to oral cavity, with salivary rinse 3~7 minutes, the daily morning and evening each one It is secondary, about 1~1.5 gram of each dosage, feel to suffer from odonthemodia after a week using the tooth powder obviously much better, breath freshening uses this One month future trouble tooth of tooth powder has good effect in acid, and when slightly firmly scraping the exterior of teeth for suffering from the nearly tooth root of tooth with nail, feels that tooth is not sour, It is had good effect in acid using three months future trouble teeth of the tooth powder, sensitivity of tooth is alleviated, which has anti-sensitivity of tooth and reduce oral peculiar smell Effect.

Claims (6)

1. a kind of composition with anti-sensitivity of tooth containing magnesium salts, which is characterized in that be grouped by the group of following mass percent At: magnesium salts 0.01%~3%, magnesium salts anion provide agent 0.01%~0.8%.

2. magnesium salts as described in claim 1 and magnesium salts anion provide agent, which is characterized in that magnesium salts is selected from magnesium sulfate, magnesium salts Anion provides agent and is selected from sodium fluoride.

3. a kind of such as application of the described in any item compositions of claim 1-2 in tooth powder.

4. a kind of tooth powder with anti-sensitivity of tooth includes tea polyphenols, rubbing agent, sweetener, which is characterized in that also comprising having the right Benefit requires the described in any item compositions of 1-2, and mass percent of the composition in entire tooth powder is 0.02%~3.8%； Mass percent of the tea polyphenols in entire tooth powder is 0.1%~40%.

5. a kind of tooth powder with anti-sensitivity of tooth includes tealeaves, rubbing agent, sweetener, which is characterized in that also comprising having the right It is required that the described in any item compositions of 1-2, mass percent of the composition in entire tooth powder is 0.02%~3.8%；Institute The tealeaves stated is selected from green tea, and mass percent of the green tea in entire tooth powder is 1%~40%.

6. if the described in any item compositions of claim 1-2 are in mouthwass, collutory, mouthwash, the agent of liquid tooth, solid Application in tooth agent, tooth film, gear rack, gel paint, tooth bead, pastille, toothpaste, tooth gel and tooth latex, feature exist In the mass percent that the composition accounts for whole components is 0.02%~3.8%.