CN109771328B - Mild children skin-refreshing composition and preparation method thereof - Google Patents
Mild children skin-refreshing composition and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a mild skin refreshing composition for children and a preparation method thereof, wherein the composition comprises the following functional components: the skin-refreshing air cushion comprises 0.1-1 wt% of bisabolol, 8-20 wt% of modified plant starch, 0.5-3 wt% of tranexamic acid and 0.1-0.5 wt% of allantoin. The modified plant starch is optimally combined with the bisabolol, the allantoin and the tranexamic acid, the modified plant starch adsorbs effective components to the maximum extent after being smeared on the skin, and after meeting excreta secreted by sweat glands, active substances are slowly released to stop bleeding, relieve the pain and relieve the itching, and simultaneously keep the water-oil balance of the skin, so that the dry and comfortable skin state of infants is kept constantly. Meanwhile, the composition is convenient to apply indoors or outdoors, the dosage form of the composition adopts an air cushion mode, the skin is cool, and the skin burden of infants is not increased.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a mild skin-refreshing composition for children and a preparation method thereof.
Background
The main components of the talcum powder are talcum powder, boric acid, magnesium carbonate, spice and the like. The talcum powder is divided into an adult powder and a child powder due to different boric acid components. The talcum powder can absorb sweat, smooth skin and reduce miliaria. The existing children toilet powder comprises traditional powder toilet powder and emulsion liquid toilet powder according to states. The product is mainly used for children after bathing to solve the problems of bacterial breeding and the like caused by secretion of skin oil and fat and sweat of children. And because the children are active, no product which is convenient to carry and can stop sweating in time is available on the market at present after sweating due to continuous movement. The sport first-aid spray product used in the market at present has the main effects on muscle sprain, inflammation diminishing and the like. The mildness of the product, as well as the resistance to continued contamination, is weak.
Disclosure of Invention
The invention aims to overcome the problems and provide a multifunctional child soothing and skin-refreshing composition which can be conveniently used indoors and outdoors and has the functions of arresting sweating, stopping bleeding and relieving itching.
In order to achieve the purpose, the invention adopts the technical scheme that the children refreshing composition comprises the following functional components: the skin care composition comprises 0.1-1 wt% of bisabolol, 8-20 wt% of modified plant starch, 0.5-3 wt% of tranexamic acid and 0.1-0.5 wt% of allantoin.
The modified plant starch is not easy to agglomerate and grow bacteria, can effectively adsorb active substances, is slowly released when being smeared, and can maintain the water-oil balance of the skin. The natural levorotatory bisabolol is used as an oil-soluble component, the water-soluble component is reasonably matched, the oil and water are balanced, the capability of absorbing oil and releasing the efficacy of the bisabolol can be realized when the skin secretes the oil, the tranexamic acid and the allantoin can be dissolved when absorbing water-based substances discharged by sweat glands and can be released to the skin through osmotic pressure to play a slow release role, and the natural levorotatory bisabolol, the modified plant starch, the tranexamic acid and the allantoin in the formula can play the roles of relieving itching, stopping bleeding and sweating and diminishing inflammation in the optimal matching proportion, so that the skin of infants is kept in a comfortable state.
In a preferred embodiment of the body refreshing composition for children of the present invention, the skin refreshing composition comprises 0.3 to 0.5% by weight of the bisabolol, 8 to 16% by weight of the modified plant starch, 1 to 1.5% by weight of the tranexamic acid, and 0.1 to 0.3% by weight of the allantoin. The effect of the composition can be influenced by the proportion of the components, and researches show that in the preferable weight percentage content range, the body-refreshing air cushion can achieve better effects in relieving itching, stopping bleeding and stopping sweating.
In a preferred embodiment of the body refreshing composition for children according to the present invention, the skin refreshing composition comprises 0.3 wt% of bisabolol, 8 wt% of the modified plant starch, 1 wt% of tranexamic acid, and 0.1 wt% of allantoin. The inventor of the present invention has unexpectedly found in a large number of experiments that, at the specific weight percentage, the cooling air cushion of the present invention achieves the best effects in relieving itching, stopping bleeding and suppressing sweating.
As a preferable embodiment of the children refreshing composition, the modified plant starch is obtained by modifying any starch of rice, cassava and corn plants, and preferably, the mesh number of the modified starch is 15-20 μm. When in use, the powder is sieved by a 200-mesh screen to obtain fine and uniform powder, and then the fine and uniform powder is subjected to formula proofing or production.
As a preferred embodiment of the body refreshing composition for children of the present invention, the body refreshing composition further comprises the following components by weight percentage: 1-20% of an emollient, 5-20% of a humectant, 0.1-1% of a thickener, 0.8-5% of a skin conditioner, 1-5% of an emulsifier and the balance of deionized water.
As a preferred embodiment of a child's body-building composition of the present invention, the emollient is caprylic/capric triglyceride; the emulsifier is C14-22 alcohol/C12-20 alkyl glucoside; the humectant is butanediol; the thickening agent is carbomer; the skin conditioner is a compound composed of hexanediol, p-hydroxyacetophenone, menthyl lactate, dipotassium glycyrrhizinate, arginine, lavender essential oil, and extracts of lavender flower and gardenia fruit.
The composition comprising lavender flower extract and gardenia fruit extract is available from blue lavenda complex of Shanghai Hanoza.
As a preferred embodiment of a child body lotion composition according to the present invention, the body lotion composition is in the form of a gas cushion body lotion. Meanwhile, the air cushion is used in a mode of being conveniently applied indoors or outdoors, only the air cushion needs to be lightly tapped to the skin, hands do not need to be cleaned after the air cushion is used, meanwhile, the air cushion gives cool feeling to the skin, the air cushion inherits the extremely simple and optimal concept, substances with volatility or cooling effects do not need to be additionally added, and the burden of the skin of the infant is increased.
The invention also provides a preparation method of the children refreshing composition, which comprises the following steps:
1) soaking the thickening agent in 8-15% of deionized water in advance until no particles exist, and stirring for 5-15 minutes at the temperature of 80-85 ℃; adding the mixture into a vacuum emulsifying pot, then adding the rest deionized water, allantoin, hexanediol and p-hydroxyacetophenone, and keeping the temperature at 80-85 ℃ and stirring to dissolve completely;
2) adding emulsifier, emollient, bisabolol, and menthyl lactate into oil pan, heating at 80 deg.C, stirring, and dissolving completely;
3) adding the mixture obtained in the step (2) into the mixture obtained in the step (1) for homogenizing and emulsifying for 3-8 minutes, then adding arginine, and stirring for 5-15 minutes under the condition of heat preservation;
4) cooling to 35-45 ℃, adding a humectant and modified plant starch, and then adding tranexamic acid, dipotassium glycyrrhizinate, lavender essential oil, lavender flower extract and gardenia fruit extract to obtain the child soothing and toning composition.
The invention has the beneficial effects that: the children soothing and skin-refreshing composition disclosed by the invention uses the optimized combination of the modified plant starch and the bisabolol, the allantoin and the tranexamic acid, the modified plant starch adsorbs the effective components to the maximum extent after being applied to the skin, and after meeting the excretion secreted by sweat glands, the modified plant starch slowly releases active substances to stop bleeding, relieve and relieve itching, and simultaneously keeps the water-oil balance of the skin, so that the dry and comfortable skin state of infants is kept constantly. Meanwhile, the air cushion is used in a mode of being convenient to apply indoors or outdoors, only the hands are required to be lightly tapped to the skin without cleaning the hands after use, and meanwhile, the air cushion can provide cool feeling to the skin, and the air cushion has a very simple and optimal concept without adding substances with volatility or cooling effects additionally, so that the burden of the skin of the infant is increased.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
The raw materials in the following examples are all commercially available general-purpose materials unless otherwise specified.
Examples 1 to 10
Examples 1-10 are examples of mild child skin care compositions according to the present invention, and the weight percentage content of each component of the child skin care compositions of examples 1-10 is shown in table 1.
The emollient in table 1 is caprylic/capric triglyceride, the emulsifier is C14-22 alcohol/C12-20 alkyl glucoside, and the humectant is butylene glycol; the thickening agent is carbomer; the skin conditioner is hexanediol, p-hydroxyacetophenone, menthyl lactate, dipotassium glycyrrhizinate, arginine, lavender essential oil, lavender flower extract and gardenia fruit extract.
TABLE 1
The preparation method of the children skin-refreshing composition provided by the embodiment 1-10 comprises the following steps:
1) soaking the thickening agent in 8-15% of deionized water in advance until no particles exist, and stirring for 5-15 minutes at the temperature of 80-85 ℃; adding the mixture into a vacuum emulsifying pot, then adding the rest deionized water, allantoin, hexanediol and p-hydroxyacetophenone, and keeping the temperature at 80-85 ℃ and stirring to dissolve completely;
2) adding emulsifier, emollient, bisabolol, and menthyl lactate into oil pan, heating at 80 deg.C, stirring, and dissolving completely;
3) adding the mixture obtained in the step (2) into the mixture obtained in the step (1) for homogenizing and emulsifying for 3-8 minutes, then adding arginine, and stirring for 5-15 minutes under the condition of heat preservation;
4) cooling to 35-45 ℃, adding a humectant and modified plant starch, and then adding tranexamic acid, dipotassium glycyrrhizinate, lavender essential oil, lavender flower extract and gardenia fruit extract to obtain the child soothing and toning composition.
Comparative examples 1 to 5
The weight percentage content of each component of the children skin-care composition of comparative examples 1-5 is shown in table 2.
TABLE 2
The skin conditioner in comparative examples 1-5 had the same content of each ingredient as in example 1, and the children's refreshing composition of comparative examples 1-5 was prepared by the same method as in example 1.
Example 11
This example was conducted to test the effect of the skin-refreshing compositions for children prepared in examples 1 to 10 and comparative examples 1 to 5.
Efficacy test for body-cooling and sweating-stopping
The test method is as follows:
test samples: examples 1 to 10, comparative examples 1 to 5, and commercial liquid toilet powder A (commercially available product).
The tested person: the 320 children aged 3-10 after exercise were randomly divided into 16 groups of 20 persons, and 16 groups of children used the products of examples 1-10 and comparative examples 1-5, respectively, which are commercially available.
Effect determination criteria:
the method has the following advantages: after the sweat is used, the sweat is absorbed until the skin is dry and comfortable, and the skin feeling is fresh and comfortable, namely the sweat is effective.
And (4) invalidation: after the sweat is used, the sweat is not completely absorbed, and the sweat still feels damp, hot and sticky, namely the sweat is ineffective.
The test results are shown in table 3:
TABLE 3
As can be seen from the data in table 3, the skin-refreshing compositions for children prepared in examples 1 to 10 of the present invention have good antiperspirant effect, the effective rates of the compositions are all above 70%, and are superior to those of the commercially available products, wherein the effective rate of example 1 is the best, and the effective rate reaches 90%, comparative example 1 is different from example 1 only in that natural l-bisabolol is absent, and the antiperspirant effect is reduced by 20% compared with example 1, because natural l-bisabolol is used as an oil-soluble component and a water-soluble component, and is reasonably matched and has oil-water balance, and when oil is secreted by skin, oil can be absorbed, and the antiperspirant effect can be achieved, and comparative example 2 is different from example 1 only in that tranexamic acid is absent, the antiperspirant effect is reduced, because tranexamic acid has the function of absorbing the water-based component discharged by sweat gland, so as to achieve the antiperspirant effect, comparative example 3 is different from example 1 only in that allantoin component is absent, and from the results, it is clear that the antiperspirant effect is also decreased because allantoin has a function of absorbing water of sweat glands, and comparative example 4 is different from example 1 only in that modified vegetable starch is absent, and the antiperspirant effect is inferior to example 1 because modified vegetable starch has a function of adsorbing tranexamic acid, allantoin, and native levalbonol, and at the same time, it is slowly released at the time of application, and water-oil balance of skin can be maintained, thereby promoting absorption of sweat by active ingredients such as tranexamic acid, allantoin, native levalbonol, and the like. The data of comparative examples 1-4 show that when the four active ingredients are compounded for use, the compound antiperspirant has the sweat absorption effect superior to that of the compound antiperspirant prepared from only one, two or three active ingredients under the condition of the same addition amount, and the compound antiperspirant prepared from the four active ingredients has stronger and longer antiperspirant effect. The content of some of the ingredients in comparative example 5 was out of the range of the present invention, and accordingly, the antiperspirant effect was also decreased, indicating that the ingredients of the present invention can exert the optimum efficacy only within the specific content range.
The examples 6 to 10 are different only in the content of the modified plant starch, tranexamic acid, allantoin and native levugenol, and as can be seen from the data in table 3, the modified plant starch, tranexamic acid, allantoin and native levugenol have a preferable antiperspirant effect when the modified plant starch, tranexamic acid and native levugenol are 8 to 16 wt%, 1 to 1.5 wt%, 0.1 to 0.3 wt% and 0.3 to 0.5 wt%, respectively.
(II) hemostasis efficacy test
Selecting 15 experimental mice with the same week age, slightly bleeding the skin of each mouse after breaking, calculating the blood coagulation time of each group of mice by using the products prepared in examples 1-10, comparative examples 1-2 and comparative examples 4-5 and the products sold in the market, and obtaining the results shown in table 4:
TABLE 4
As can be seen from the data in table 4, the skin-refreshing composition for children prepared in examples 1 to 10 of the present invention has a good blood coagulation effect, the effective rate of the composition is blood coagulation within 2.5min, which is superior to the commercial product, wherein the effect of example 1 is the best, and blood coagulation can be achieved within 0.5min, and comparative example 1 is different from example 1 only in that a natural laevorotatory bisabolol component is absent, and the blood coagulation effect is increased to 1.5min compared to example 1 because the oil-soluble component, the water-soluble component, the reasonable collocation and the oil-water balance of the natural laevorotatory bisabolol can absorb oil and fat when the skin secretes oil, so as to promote the release capacity of tranexamic acid, and the natural laevorotatory bisabolol can prevent and reduce inflammation, heal wound, and can nourish and moisturize dry skin, and has deodorization and sterilization effects. Comparative example 2 is different from example 1 only in that tranexamic acid component is absent, and coagulation effect is reduced because tranexamic acid belongs to the class of fibrinolysis inhibitor, and plasminogen can not be converted into plasmin by reversibly blocking lysine binding site on plasminogen molecule, thereby effectively inhibiting fibrinolysis and generating hemostasis effect. The comparative example 3 is different from the example 1 only in that allantoin is lacked, and the allantoin has physiological functions of promoting cell growth, accelerating wound healing and the like and is a good healing agent for skin wounds. Thus, the clotting time of comparative example 3 was longer than that of example 1. Comparative example 4 is different from example 1 only in that modified plant starch is absent, and the coagulation effect is inferior to example 1, because the modified plant starch has the function of adsorbing tranexamic acid, allantoin and natural levorotatory bisabolol, is slowly released when being smeared, and can maintain the water-oil balance of the skin, thereby promoting the active ingredients such as tranexamic acid, allantoin and natural levorotatory bisabolol to exert the effects of coagulation and accelerating wound healing. The data of comparative examples 1-4 show that when the four active ingredients are compounded for use, the blood coagulation effect of the four active ingredients is better than that of one, two or three active ingredients only under the condition of the same addition amount, and the blood coagulation effect of the four active ingredients is stronger and quicker.
The content of some of the components in comparative example 5 was out of the range of the present invention, and accordingly, the coagulation effect was also decreased, indicating that the components of the present invention can exert the optimum effect only within the specific content range.
The difference between examples 6 and 10 is only that the contents of the modified plant starch, tranexamic acid, allantoin and native levalbonol are different, and as can be seen from the data in table 3, the modified plant starch has a better coagulation effect when the contents of the modified plant starch, the tranexamic acid, the allantoin and the native levalbonol are 8 to 16 wt%, 1 to 1.5 wt%, 0.1 to 0.3 wt% and 0.3 to 0.5 wt%, respectively.
(III) test of relieving itching Effect
Selecting 16 experimental white mice with the week age of 8-10 weeks, smearing the back skin of the white mice with histamine respectively, smearing the back skin of the white mice with the histamine immediately by using the examples 1-10, the comparative examples 1-5 and a product sold in the market, counting the number of scratching of the white mice within 30 minutes, and counting the results as shown in Table 5:
TABLE 5
As can be seen from the data in table 5, the skin-refreshing compositions for children prepared in examples 1 to 10 of the present invention have good effect of relieving itching, and the number of scratching itching is smaller than that of commercial products, wherein the best effect is obtained in example 1, and the number of scratching is 16 within 30min, and comparative examples 1 to 4 are different from example 1 only in that natural l-bisabolol, tranexamic acid, allantoin, and modified plant starch are respectively absent, and the corresponding effect of relieving itching is also reduced, because the natural l-bisabolol having the effect of relieving is an oil-soluble component, a water-soluble component, a reasonable combination, and an oil-water balance, and can absorb oil when the skin secretes the oil, thereby promoting the release capacity of the bisabolol, and protecting and caring the allergic skin. The allantoin can help skin to resist inflammation, relieve and promote cell repair, and the modified plant starch has the effects of adsorbing tranexamic acid, allantoin and natural L-bisabolol, and can be slowly released when being applied, and can maintain the water-oil balance of skin, thereby promoting the effects of active ingredients such as tranexamic acid, allantoin and natural L-bisabolol. The data of comparative examples 1-4 show that when the four active ingredients are compounded for use, under the condition of the same addition amount, the composite has a better effect of relieving itching than the effect of relieving itching by only using one, two or three active ingredients, and the effect of relieving itching by compounding the four active ingredients is stronger and longer. The content of some of the ingredients in comparative example 5 was out of the range of the present invention, and accordingly, the soothing effect was also decreased, indicating that the ingredients of the present invention can exert the best effects only within the specific content range.
The examples 6 to 10 are different only in the content of the modified plant starch, tranexamic acid, allantoin, and native levugenol, and as can be seen from the data in table 3, the modified plant starch, tranexamic acid, allantoin, and native levugenol have a preferable anti-itching effect when the modified plant starch, tranexamic acid, and native levugenol are 8 to 16 wt%, 1 to 1.5 wt%, 0.1 to 0.3 wt%, and 0.3 to 0.5 wt%, respectively.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (7)
1. A children skin-refreshing composition is characterized by comprising the following functional components: the skin care composition comprises 0.3-0.5 wt% of bisabolol, 8-16 wt% of modified plant starch, 1-1.5 wt% of tranexamic acid and 0.1-0.3 wt% of allantoin, wherein the modified plant starch is obtained by modifying corn plant starch, and the mesh number of the modified starch is 15-20 mu m.
2. The pediatric skin rejuvenation composition of claim 1 wherein the bisabolol is present in an amount of 0.3 weight percent, the modified plant starch is present in an amount of 8 weight percent, the tranexamic acid is present in an amount of 1 weight percent, and the allantoin is present in an amount of 0.1 weight percent of the rejuvenation composition.
3. The children's skin care composition of claim 1, further comprising the following components in weight percent: 1-20% of an emollient, 5-20% of a humectant, 0.1-1% of a thickener, 0.8-5% of a skin conditioner, 1-5% of an emulsifier and the balance of deionized water.
4. The pediatric skin rejuvenation composition according to claim 3 wherein said emollient is caprylic/capric triglyceride; the emulsifier is C14-22 alcohol/C12-20 alkyl glucoside; the humectant is butanediol; the thickening agent is carbomer; the skin conditioner is a compound composed of hexanediol, p-hydroxyacetophenone, menthyl lactate, dipotassium glycyrrhizinate, arginine, lavender essential oil and lavender flower extract and gardenia fruit extract.
5. The children's skin care composition according to claim 4, wherein the skin conditioning agent comprises the following components in percentage by weight of the children's skin care composition: 0.3-0.6% of hexanediol, 0.3-0.6% of p-hydroxyacetophenone, 0.05-0.5% of menthyl lactate, 0.02-0.2% of dipotassium glycyrrhizinate, 0.1-1.5% of arginine, 0.02-0.1% of lavender essential oil and 0.01-1% of a compound consisting of a lavender flower extract and a gardenia fruit extract.
6. The pediatric skin rejuvenation composition according to any one of claims 3 to 5 wherein the skin rejuvenation composition is in the form of a gas cushion skin rejuvenation emulsion.
7. A process for preparing a child's skin-soothing composition according to claim 6, comprising the steps of:
1) soaking the thickening agent in 8-15% of deionized water in advance until no particles exist, and stirring for 5-15 minutes at the temperature of 80-85 ℃; adding the mixture into a vacuum emulsifying pot, then adding the rest deionized water, allantoin, hexanediol and p-hydroxyacetophenone, and keeping the temperature at 80-85 ℃ and stirring to dissolve completely;
2) adding emulsifier, emollient, bisabolol, and menthyl lactate into oil pan, heating at 80 deg.C, stirring, and dissolving completely;
3) adding the mixture obtained in the step 2) into the mixture obtained in the step 1) for homogenizing and emulsifying for 3-8 minutes, then adding arginine, and stirring for 5-15 minutes under the condition of heat preservation;
4) cooling to 35-45 ℃, adding a humectant and modified plant starch, and then adding tranexamic acid, dipotassium glycyrrhizinate, lavender essential oil, lavender flower extract and gardenia fruit extract to obtain the child soothing and toning composition.
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| JPH09291012A (en) * | 1996-04-25 | 1997-11-11 | Sunstar Inc | Antiphlogistic skin cosmetic |
| WO1998011877A1 (en) * | 1996-09-18 | 1998-03-26 | Dragoco, Inc. | Liposome encapsulated active agent dry powder composition |
| CN104107159A (en) * | 2014-06-27 | 2014-10-22 | 陈海 | Cosmetic and preparation method thereof |
| CN106063774A (en) * | 2016-03-31 | 2016-11-02 | 福建欧柏亚日化有限公司 | A kind of Semen Maydis soft liquid talcum powder |
| CN109091411A (en) * | 2018-11-13 | 2018-12-28 | 王亚平 | A kind of infant's lotion and preparation method thereof |
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2019
- 2019-01-24 CN CN201910071826.XA patent/CN109771328B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09291012A (en) * | 1996-04-25 | 1997-11-11 | Sunstar Inc | Antiphlogistic skin cosmetic |
| WO1998011877A1 (en) * | 1996-09-18 | 1998-03-26 | Dragoco, Inc. | Liposome encapsulated active agent dry powder composition |
| CN104107159A (en) * | 2014-06-27 | 2014-10-22 | 陈海 | Cosmetic and preparation method thereof |
| CN106063774A (en) * | 2016-03-31 | 2016-11-02 | 福建欧柏亚日化有限公司 | A kind of Semen Maydis soft liquid talcum powder |
| CN109091411A (en) * | 2018-11-13 | 2018-12-28 | 王亚平 | A kind of infant's lotion and preparation method thereof |
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