CN109694805A - A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar - Google Patents

A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar Download PDF

Info

Publication number
CN109694805A
CN109694805A CN201910066450.3A CN201910066450A CN109694805A CN 109694805 A CN109694805 A CN 109694805A CN 201910066450 A CN201910066450 A CN 201910066450A CN 109694805 A CN109694805 A CN 109694805A
Authority
CN
China
Prior art keywords
fruit juice
filtrate
alcoholic drink
drink mixed
filter residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910066450.3A
Other languages
Chinese (zh)
Inventor
赵为兴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201910066450.3A priority Critical patent/CN109694805A/en
Publication of CN109694805A publication Critical patent/CN109694805A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/05Chlorophycota or chlorophyta (green algae), e.g. Chlorella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of formulas of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, are mainly prepared by tea extract, fructus cannabis alcoholic drink mixed with fruit juice, cortex cinnamomi, haematococcus pluvialis, Radix Astragali, mulberry leaf, pueraria lobata, Chinese yam and lemon alcoholic drink mixed with fruit juice;The tea extract is prepared by dry aged tea leaf;The fructus cannabis alcoholic drink mixed with fruit juice is mainly prepared by fructus cannabis, betadex, edible alcohol.The present invention is with reference to traditional chinese medicine to the Couple herbs of diabetes, modern scientific research achievement is utilized again peculiarly, for the first time tea extract and a variety of dual-purpose of drug and food natural plants compatible uses such as astaxanthin and cannabinoids and cortex cinnamomi, mulberry leaf, Chinese yam, collaboration plays, it activates the activity of glucokinase and hexokinase, improve the sensibility of insulin, promote insulin secretion, increases the content of serum insulin and have the function of adjusting blood glucose, there is certain auxiliary therapeutic action to diabetes.

Description

A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar
Technical field
The present invention relates to alcoholic drink mixed with fruit juice production technical field, the formula and preparation method thereof of specifically a kind of friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar.
Background technique
Alcoholic drink mixed with fruit juice is using Spirit, fermented wine or edible alcohol as wine base, with the animals and plants essence of dual-purpose of drug and food, by advanced work Skill is process, and changes the alcoholic drink of its former wine base style.
Alcoholic drink mixed with fruit juice has the characteristics that full of nutrition, various in style, different style, including flowers and fruits type alcoholic drink mixed with fruit juice, animals and plants aroma type, The wine product such as tonic nutrient liquor.
Diabetes (diabetes) are by inherent cause, immunologic function disorder, microorganism infection and its toxin, free radical poison Element, the various virulence factors of mental element etc. act on body lead to hypoinsulinism, insulin resistance etc. and cause sugar, A series of metabolic disorder syndromes such as protein, fat, water and electrolyte, clinically using hyperglycemia as main feature, typical disease Example may occur in which the performances such as diuresis, more drinks, more food, syntexis, i.e., " three-many-one-little " symptom, diabetes (blood glucose) once control bad meeting Cause complication, leads to the failure lesion at the positions such as kidney, eye, foot, and can not cure.International Diabetes Federation announces sugar in 2017 Patient's number is urinated up to 4.25 hundred million.The current diabetic of China, about more than 100,000,000 people.
Summary of the invention
The present invention provides a kind of formula and preparation method thereof of friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, there is certain adjuvant treatment for diabetes Effect.
The present invention protects a kind of formula of friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, mainly raw by tea extract, fructus cannabis alcoholic drink mixed with fruit juice, cortex cinnamomi, rain Haematococcus, Radix Astragali, mulberry leaf, pueraria lobata, Chinese yam and lemon alcoholic drink mixed with fruit juice are prepared;The tea extract passes through dry aged tea leaf preparation It obtains;The fructus cannabis alcoholic drink mixed with fruit juice is mainly prepared by fructus cannabis, betadex, edible alcohol.
The present invention also protects a kind of preparation method of friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, comprising the following steps:
Step 1: haematococcus pluvialis being added in 95% or more edible ethanol of triplication and flowed back twice, merge filtrate twice, water-bath It is concentrated into primary doses, obtains cream liquid A;
Step 2: by cortex cinnamomi: Radix Astragali: mulberry leaf: pueraria lobata: Chinese yam: the mixing milling of 2:1:2:1:1 in mass ratio is packed into cotton bag, Obtain ingredient B;
Step 3: by sealed soak 7-10d in the fructus cannabis alcoholic drink mixed with fruit juice of ingredient B investment quintuple, obtaining mixing wine liquid C;
Step 4: by tea extract and cream liquid A and mixing wine liquid C and mix, wine liquid D must be mixed;
Step 5: being filtered after mixing wine liquid D is mixed with lemon alcoholic drink mixed with fruit juice according to the mass ratio of 1:1, filtrate is under the conditions of 18-26 DEG C After standing 7-10d, filters again, obtain filtrate E;
Step 6: standard is executed by alcoholic drink mixed with fruit juice GB/T27588--2011, with pure water or height edible ethanol adjustment alcoholic strength and always Sugar.
Further, 1. the tea extract preparation method in the step 4 is the following steps are included: be added three by stem tea Again in the pure water of amount, after impregnating 10-15 clock, is filtered after water bath sonicator processing 15-30min, obtain filtrate F, filter residue G;2. will be again He is added in the pure water of triplication cyclodextrin, and filtrate F is added after being completely dissolved, stirs 30min under the conditions of 50 DEG C of constant temperature, stops It only heats, continues stirring 8 hours at room temperature, obtain Solution H;Betadex and the mass ratio of the primary doses of stem tea are 1:3;③ Filter residue G is added in the pure water by the primary doses triplication of stem tea, water-bath 30min under the conditions of 80-85 DEG C, filtering obtains Filtrate I;4. filtrate H and filtrate I are tea extract.
Further, the preparation method of the fructus cannabis alcoholic drink mixed with fruit juice includes the following steps the preparation method of the fructus cannabis alcoholic drink mixed with fruit juice The following steps are included: 1. screening, that is, select full grains, the fructus cannabis without moldy metamorphism, free from insect pests;2. toasting, after screening Fructus cannabis raw material grind to 5 mesh more than, be laid on drip pan, be put into oven braking, 160 DEG C of baking temperature, duration 30min is dried to moisture lower than 8%;3. impregnating extraction, immersion extraction first is carried out to fructus cannabis powder with edible alcohol, after filtering After the filter residue drying arrived, then with petroleum ether immersion extraction is carried out, specifically includes the following steps: fructus cannabis powder is pressed with edible alcohol Solution A is mixed into according to the mass ratio of 1:5 ', it stirs at room temperature, impregnate and filter afterwards for 24 hours, obtain filtrate A ', filter residue A ';By filter residue A ' with Edible alcohol is mixed into solution B according to the mass ratio of 1:3 ', at room temperature stir, impregnate filter afterwards for 24 hours, obtain liquor B ', filter residue B '; Filter residue B ' is put into oven baking, its moisture content is dried to 3-5%;According to the mass ratio of 1:1, it is added into the filter residue B ' of drying Petroleum ether obtains solution C ', solution C ' water bath sonicator 30min, at room temperature stir, impregnate 2h, filtering, obtain liquor C ', filter residue C ';It presses Solution D is obtained to petroleum ether is added in filter residue C ' according to the mass ratio of 1:1 ', solution D ' water bath sonicator 30min is stirred at room temperature, is soaked 2h is steeped, filtering obtains filtrate D ', filter residue D ', and stirring, soaking temperature are no more than 50 DEG C;By liquor C ', after filtrate D ' steaming petroleum ether Paste, by 1:5 mass ratio be added edible alcohol, flow back 2h after filter, obtain filtrate E ', filter residue E ';Filter residue E ' is by 1:5's Edible alcohol is added in mass ratio, filters after the 2h that flows back, obtains filtrate F ', filter residue F ';4. by filtrate A ', liquor B ', filtrate E ', filtrate It is filtered after F ' mixing, obtains filtrate P ';5. food grade betadex is weighed according to the 8% of fructus cannabis material quality ratio, according to 1:5 Mass ratio be added pure water, stir at 50 °C, after betadex is completely dissolved, be slowly added to filtrate P ', after After continuous stirring 30min, stop heating, continues after stirring 8h, filter to get filtrate Q ';6. to appropriate Radix Angelicae Sinensis is added in the filtrate Q ' Extract, capejasmine extract, lemon extract and granulated sugar, angelica extract, capejasmine extract, lemon extract and granulated sugar add Dosage is adjusted according to taste;7. adjusting the alcoholic strength of alcoholic drink mixed with fruit juice by addition pure water or edible alcohol.
The present invention with reference to traditional chinese medicine to the Couple herbs of diabetes, and it is peculiar using modern scientific research at Fruit for the first time matches tea extract and a variety of dual-purpose of drug and food natural plants such as astaxanthin and cannabinoids and cortex cinnamomi, mulberry leaf, Chinese yam 5 use, and collaboration plays, and activate the activity of glucokinase and hexokinase, improve the sensibility of insulin, promote insulin Secretion increases the content of serum insulin and has the function of adjusting blood glucose, there is certain auxiliary therapeutic action to diabetes;And And it is convenient, 25-50mL is taken daily, is taken convenient for medium-term and long-term, no drinking person, and water-bath boils off wine degree before can taking.
Specific embodiment
The present invention will be further described in detail with reference to the specific embodiments.The embodiment of the present invention is to show It is provided for the sake of example and description, and is not exhaustively or to limit the invention to disclosed form.Many modifications and Variation is obvious for the ordinary skill in the art.Selection and description embodiment are to more preferably illustrate this The principle and practical application of invention, and make those skilled in the art it will be appreciated that the present invention is to which design is suitable for specific The various embodiments with various modifications of purposes.
Embodiment 1
A kind of formula of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, mainly by tea extract, fructus cannabis alcoholic drink mixed with fruit juice, cortex cinnamomi, haematococcus pluvialis, Radix Astragali, mulberry Leaf, pueraria lobata, Chinese yam and lemon alcoholic drink mixed with fruit juice are prepared;The tea extract is prepared by dry aged tea leaf;The fire fiber crops Benevolence alcoholic drink mixed with fruit juice is mainly prepared by fructus cannabis, betadex, edible alcohol.
The preparation method of the above-mentioned friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar the following steps are included:
Step 1: haematococcus pluvialis being added in 95% or more edible ethanol of triplication and flowed back twice, merge filtrate twice, water-bath It is concentrated into primary doses, obtains cream liquid A;
Step 2: by cortex cinnamomi: Radix Astragali: mulberry leaf: pueraria lobata: Chinese yam: the mixing milling of 2:1:2:1:1 in mass ratio is packed into cotton bag, Obtain ingredient B;
Step 3: by sealed soak 7-10d in the fructus cannabis alcoholic drink mixed with fruit juice of ingredient B investment quintuple, obtaining mixing wine liquid C;
Step 4: by tea extract and cream liquid A and mixing wine liquid C and mix, wine liquid D must be mixed;
Step 5: being filtered after mixing wine liquid D is mixed with lemon alcoholic drink mixed with fruit juice according to the mass ratio of 1:1, filtrate is under the conditions of 18-26 DEG C After standing 7-10d, filters again, obtain filtrate E;
Step 6: standard is executed by alcoholic drink mixed with fruit juice GB/T27588--2011, with pure water or height edible ethanol adjustment alcoholic strength and always Sugar.
The effect of a kind of effect of raw material is not equal to its each raw material it is simple cumulative, there are phases after each material combination combination The relationship of a variety of interactions such as life, mutual reinforcement between, mutual restraint between two drugs or the mutual-detoxication;The increase and decrease of each raw material component, the number of dosage can all make the group Complicated variation occurs for the function for closing object;These variations include the enhancing of original effect or the disappearance of decrease or original effect, Even generating opposite side effect.The present invention with reference to traditional chinese medicine to the Couple herbs of diabetes, and peculiar ground Using modern scientific research achievement, tea extract and a variety of medicines such as astaxanthin and cannabinoids and cortex cinnamomi, mulberry leaf, Chinese yam are eaten for the first time Dual-purpose natural plants compatible use, collaboration play, and activate the activity of glucokinase and hexokinase, improve the sensitivity of insulin Property, promote insulin secretion, increase the content of serum insulin and have the function of adjusting blood glucose, proves by verifying to glycosuria Disease has certain auxiliary therapeutic action.
Cortex cinnamomi has the function of reducing blood glucose, adjusts blood lipid, and mechanism of action is to protect and stimulate beta Cell of islet, to promote Into insulin secretion, increase the content of serum insulin;The sensibility of insulin is improved, Insulin Resistance is improved.
Radix Astragali has the function of increasing insulin sensitivity and reduces blood glucose to diabetic.Chinese herbal medicine astragalus can pass through Increase glycogen synthase activity, insulin receptor substrate activity, protein kinase B and protein kinase C activity, makes Glycogen synthesis enzyme activity Property increase and play increase insulin sensitivity, reduce blood glucose effect.
Mulberry leaf, mulberry leaf polysaccharide can alleviate diabetic symptom, and control diabetes fasting blood sugar increases, and reduce saccharification serum egg White and Area under the curve of blood glucose effect, can promote the synthesis of serum insulin, the secretion of liver HK and liver glycogen.
Pueraria lobata, can relieving muscles diaphoresis, invigorating vital function and promoting eruption, it is antipyretic promote the production of body fluid, have significant hypoglycemic effect, Chinese yam, experimental study Show there is hypoglycemic effect.Chinese medicine ancient prescription controls diabetes and often adds Chinese yam.
Haematococcus pluvialis will use containing superpower antioxidant astaxanthin is taken orally to treat the exogenous pancreas islet of diabetes Element --- insulin injection does not have habituation and dependence.
Chromium is the essential trace elements of the human body, lacks the people of chromium, and insulin just loses effect, causes the oxidation of sugar very slow Slowly.Chromium can activate insulin, and Cr3+ strengthens the physiological function of insulin as the active constituent of glucose tolerance factor (GTF), To reduce blood glucose, contain a certain amount of Organic Chromium in ingredient mulberry leaf, Chinese yam.Lemon alcoholic drink mixed with fruit juice is used for hydrotropy, synergy.
Tea extract is primarily referred to as tea polysaccharide, tea polyphenols and theanine.
Tea polysaccharide: a glucosidase inhibitor --- the absorption for inhibiting carbohydrate, i.e., to small intestine a- glucuroide It is active to have inhibiting effect and significantly increase liver glucose kinases and hexokinase activity shows apparent hypoglycemic energy Power can also enhance the activity of pancreas islet, secret out of more insulin, carry out the level of blood glucose in control volume.
In the activity to activation glucokinase and hexokinase, collaboration plays hypoglycemic work for tea polyphenols and tea polysaccharide With.
1. the tea extract preparation method that the present embodiment is used is the following steps are included: be added triplication for old stem tea Pure water in, impregnate 10-15 clock after, water bath sonicator processing 15-30min after filter, obtain filtrate F, filter residue G;2. inciting somebody to action his ring again Dextrin is added in the pure water of triplication, and filtrate F is added after being completely dissolved, and in 50 DEG C of constant temperature, (tea polysaccharide must be in 50 DEG C of items Extracted under part) under the conditions of stir 30min, stop heating, continue stirring 8 hours at room temperature, obtain the solution rich in tea polysaccharide H;Betadex and the mass ratio of the primary doses of stem tea are 1:3;3. filter residue G is added and presses the primary doses triplication of stem tea Pure water in, water-bath 30min under the conditions of 80-85 DEG C (tea polyphenols, theanine are extracted under 80 DEG C of conditions above), mistake Filter, obtains the filtrate I rich in tea polyphenols and theanine;4. filtrate H and filtrate I are tea extract.
Use betadex, be because the polysaccharide that extracts be in wine it is less soluble (polysaccharide component of plant, no Easily or it is insoluble in wine), it is wrapped using " micro-capsule " of betadex, guarantee solubility of the polysaccharide in wine, improves human body Absorptivity and bioavilability.
The preparation method of the fructus cannabis alcoholic drink mixed with fruit juice includes the following steps that the preparation method of the fructus cannabis alcoholic drink mixed with fruit juice includes following Step: 1. screening, that is, selects full grains, the fructus cannabis without moldy metamorphism, free from insect pests;2. toasting, by the fructus cannabis after screening It more than raw material grind to 5 mesh, is laid on drip pan, is put into oven braking, 160 DEG C of baking temperature, duration 30min is dried to Moisture is lower than 8%;3. impregnating extraction, immersion extraction first is carried out to fructus cannabis powder with edible alcohol, the filter residue drying obtained after filtering Afterwards, then with petroleum ether immersion extraction is carried out, specifically includes the following steps: by fructus cannabis powder and edible alcohol according to the quality of 1:5 Than being mixed into solution A ', it stirs at room temperature, impregnate and filter afterwards for 24 hours, obtain filtrate A ', filter residue A ';Filter residue A ' is pressed with edible alcohol Be mixed into solution B according to the mass ratio of 1:3 ', at room temperature stir, impregnate filter afterwards for 24 hours, obtain liquor B ', filter residue B ';Filter residue B ' is put Enter oven baking, its moisture content is dried to 3-5%;According to the mass ratio of 1:1, petroleum ether is added into the filter residue B ' of drying, obtains molten Liquid C ', solution C ' water bath sonicator 30min, at room temperature stir, impregnate 2h, filtering, obtain liquor C ', filter residue C ';According to the quality of 1:1 Than obtaining solution D to petroleum ether is added in filter residue C ' ', solution D ' water bath sonicator 30min is stirred at room temperature, is impregnated 2h, filters, Filtrate D ', filter residue D ' are obtained, stirring, soaking temperature are no more than 50 DEG C;By liquor C ', the paste after filtrate D ' steaming petroleum ether, Edible alcohol is added by the mass ratio of 1:5, is filtered after the 2h that flows back, obtains filtrate E ', filter residue E ';Filter residue E ' is added by the mass ratio of 1:5 Enter edible alcohol, is filtered after the 2h that flows back, obtain filtrate F ', filter residue F ';4. by filtrate A ', liquor B ', filtrate E ', filtrate F ' mixing after Filtering, obtains filtrate P ';5. food grade betadex is weighed according to the 8% of fructus cannabis material quality ratio, according to the mass ratio of 1:5 Pure water is added, stirs at 50 °C, after betadex is completely dissolved, is slowly added to filtrate P ', continues to stir After 30min, stop heating, continues after stirring 8h, filter to get filtrate Q ';6. being extracted to appropriate Radix Angelicae Sinensis is added in the filtrate Q ' Object, capejasmine extract, lemon extract and granulated sugar, angelica extract, capejasmine extract, lemon extract and granulated sugar additive amount It is adjusted according to taste;7. adjusting the alcoholic strength of alcoholic drink mixed with fruit juice by addition pure water or edible alcohol.
The edible alcohol referred in above-mentioned fructus cannabis alcoholic drink mixed with fruit juice preparation method is 95%vol or more, because of having in fructus cannabis A little ingredient indissolubles or not soluble in water, but it is dissolved in organic solvent alcohol, and alcoholic strength is higher, ingredient therein is just easy to leach.This Invention first carries out immersion extraction to fructus cannabis powder with edible alcohol, that is, ethyl alcohol, after the filter residue drying obtained after filtering, then uses petroleum Ether carries out immersion extraction, and first inorganic compound, small-molecule substance are extracted with ethyl alcohol, then in petroleum ether extraction raw material Organic compound, so that the inorganic compound and organic compound in raw material are fully extracted out;Recycle betadex It is wrapped, extract ingredient is wrapped up, adjustable mouthfeel, increase solubility, especially increase bioavilability, together When keep sugared friendly tender tea leaves alcoholic drink mixed with fruit juice color bright orange.
The main component of fructus cannabis is wrapped in its histocyte, and cell periphery is one layer of cellulose, hemicellulose and fruit The cell wall of the material compositions such as glue is plasm in cell wall.It is molten in solution A, the step 3.2 in the step 3.1 Solution C in liquid B, the step 3.4 can destroy plasmic physiology function in stirring, the preceding water bath sonicator 30min of immersion Can, so that the effective component and other solable matters in fructus cannabis histocyte penetrate into outside cell, improve recovery rate.
130-160 DEG C of baking temperature in the step 3.3, duration 15-35min, being mainly used for will be in fructus cannabis powder Moisture content is baked between 3-5%, reduces the water content in filter residue B, improves extraction of the fructus cannabis internal component in petroleum ether Rate, and promote cannabidiol this ingredient maturation in fructus cannabis, making it, there is no bioactivity, to will not be converted into Four phenol of hemp of poison.
The formula and preparation method thereof of fructus cannabis alcoholic drink mixed with fruit juice is disclosed in the application for a patent for invention that applicant applies early period In 201811473030.9.
Application Example 1
Jinan City, Shandong Province vial factory, Lee master worker suffer from diabetes year high disease deeply, and glucose in urine generally in four plus siges, starts to take sugar The friendly daily 25-50mL of tender tea leaves alcoholic drink mixed with fruit juice, only takes a piece of glibenclamide daily, and glucose in urine can be controlled in 1-2 plus sige;It takes two months Afterwards, withdraw glibenclamide, only take sugared friendly tender tea leaves alcoholic drink mixed with fruit juice and vitamin, glucose in urine is micro or disappears, some complication such as hand of diabetes Arm numbness etc. take a favorable turn, and then withdraws sugared friendly tender tea leaves alcoholic drink mixed with fruit juice, but just have uncomfortable feeling again after one month, then continues to take again Sugared friend's tender tea leaves alcoholic drink mixed with fruit juice takes the rear state of an illness and gets back improvement.
Application Example 2
Leave one's post worker for In Kuandian, Liaoning Province, and king xx, thirsty urine is more, general weakness, blood glucose 17.6, three plus siges of glucose in urine, and hospital is true It examines as diabetes.Take sugared friendly tender tea leaves alcoholic drink mixed with fruit juice 25-50mL daily afterwards, after eight or nine months, blood glucose 6.2, glucose in urine is without plus sige, body Restore normal.
Application Example 3
Sichuan Province, military subarea cadre's sanitarium, inland river, section xx suffer from diabetes more than ten years, are diagnosed as dependent/non-dependent pancreas islet patients with type Ⅰ DM, blood There is bleeding blister in sugar 16.87, double toe head many places, and the rotten red watery blood of stream is more than, and toe has deformed, binocular cataract, fundus hemorrhage, depending on Power decline.Glibenclamide is taken, insulin injection has used many methods also ineffective.The friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar is attempted afterwards, is taken daily 25-50mL, blood glucose assessment is down to 11.00 after two weeks, is down to 8.8 again after two months, and the bleeding blister on toe has been fully recovered, white There has also been be clearly better for cataract or glaucoma;So far still adhere to taking sugared friendly tender tea leaves alcoholic drink mixed with fruit juice daily, control the medicines of diabetes full cut-off, feel good It is good.
Obviously, described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, this field and those of ordinary skill in the related art institute without creative labor The every other embodiment obtained, all should belong to the scope of protection of the invention.

Claims (7)

1. a kind of formula of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, which is characterized in that mainly red by tea extract, fructus cannabis alcoholic drink mixed with fruit juice, cortex cinnamomi, rain life Ball algae, Radix Astragali, mulberry leaf, pueraria lobata, Chinese yam and lemon alcoholic drink mixed with fruit juice are prepared.
2. the formula of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar according to claim 1, which is characterized in that the tea extract is old by what is done Tealeaves is prepared.
3. the formula of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar according to claim 1, which is characterized in that the fructus cannabis alcoholic drink mixed with fruit juice is mainly by fiery fiber crops Benevolence, betadex, edible alcohol are prepared.
4. a kind of preparation method of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar, which comprises the following steps:
Step 1: haematococcus pluvialis being added in 95% or more edible ethanol of triplication and flowed back twice, merge filtrate twice, water-bath It is concentrated into primary doses, obtains cream liquid A;
Step 2: by cortex cinnamomi: Radix Astragali: mulberry leaf: pueraria lobata: Chinese yam: the mixing milling of 2:1:2:1:1 in mass ratio is packed into cotton bag, Obtain ingredient B;
Step 3: by sealed soak 7-10d in the fructus cannabis alcoholic drink mixed with fruit juice of ingredient B investment quintuple, obtaining mixing wine liquid C;
Step 4: by tea extract and cream liquid A and mixing wine liquid C and mix, wine liquid D must be mixed;
Step 5: being filtered after mixing wine liquid D is mixed with lemon alcoholic drink mixed with fruit juice according to the mass ratio of 1:1, filtrate is under the conditions of 18-26 DEG C After standing 7-10d, filters again, obtain filtrate E;
Step 6: standard is executed by alcoholic drink mixed with fruit juice GB/T27588--2011, with pure water or height edible ethanol adjustment alcoholic strength and always Sugar.
5. the preparation method of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar according to claim 4, which is characterized in that the tealeaves in the step 4 mentions Object preparation method is taken the following steps are included: 1. stem tea is added in the pure water of triplication, after impregnating 10-15 clock, water-bath is super It is filtered after sonication 15-30min, obtains filtrate F, filter residue G;2. betadex is added in the pure water of triplication, it is completely molten Filtrate F is added after solution, 30min is stirred under the conditions of 50 DEG C of constant temperature, stops heating, continues stirring 8 hours at room temperature, obtains Solution H; 3. filter residue G is added in the pure water by the primary doses triplication of stem tea, water-bath 30min under the conditions of 80-85 DEG C, filtering, Obtain filtrate I;4. filtrate H and filtrate I are tea extract.
6. the preparation method of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar according to claim 5, which is characterized in that betadex and stem tea are former The mass ratio of raw material amount is 1:3.
7. the preparation method of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar according to claim 5, which is characterized in that the preparation of the fructus cannabis alcoholic drink mixed with fruit juice Method includes the following steps the preparation method of the fructus cannabis alcoholic drink mixed with fruit juice the following steps are included: 1. screening, that is, selects full grains, nothing Moldy metamorphism, free from insect pests fructus cannabis;2. toasting, more than the fructus cannabis raw material grind to 5 mesh after screening, it is laid in drip pan On, it is put into oven braking, 160 DEG C of baking temperature, duration 30min, is dried to moisture lower than 8%;3. extraction is impregnated, first with edible Alcohol carries out immersion extraction to fructus cannabis powder, after the drying of the filter residue that obtains after filtering, then with petroleum ether carries out immersion extraction, specifically The following steps are included: fructus cannabis powder and edible alcohol are mixed into solution A according to the mass ratio of 1:5 ', it stirs, impregnate at room temperature It filters afterwards for 24 hours, obtains filtrate A ', filter residue A ';Filter residue A ' and edible alcohol are mixed into solution B according to the mass ratio of 1:3 ', room temperature It is lower stirring, impregnate filter afterwards for 24 hours, obtain liquor B ', filter residue B ';Filter residue B ' is put into oven baking, its moisture content is dried to 3-5%; According to the mass ratio of 1:1, petroleum ether is added into the filter residue B ' of drying, obtains solution C ', solution C ' water bath sonicator 30min, room temperature It is lower stirring, impregnate 2h, filtering, obtain liquor C ', filter residue C ';It is obtained molten according to the mass ratio of 1:1 to petroleum ether is added in filter residue C ' Liquid D ', solution D ' water bath sonicator 30min are stirred at room temperature, are impregnated 2h, and filtering obtains filtrate D ', filter residue D ', stirring, soaking temperature No more than 50 DEG C;By liquor C ', the paste after filtrate D ' steaming petroleum ether, edible alcohol, reflux is added by the mass ratio of 1:5 It is filtered after 2h, obtains filtrate E ', filter residue E ';Edible alcohol is added by the mass ratio of 1:5 in filter residue E ', filters after the 2h that flows back, obtains filtrate F ', filter residue F ';4. by filtrate A ', liquor B ', filtrate E ', filtrate F ' mixing after filter, obtain filtrate P ';5. according to fructus cannabis raw material The 8% of mass ratio weighs food grade betadex, and pure water is added according to the mass ratio of 1:5, stirs at 50 °C, to After betadex is completely dissolved, it is slowly added to filtrate P ', continues after stirring 30min, stops heating, is continued after stirring 8h, mistake Filter to obtain filtrate Q ';6. to appropriate angelica extract, capejasmine extract, lemon extract and granulated sugar are added in the filtrate Q ', when The additive amount of extract, capejasmine extract, lemon extract and granulated sugar is returned to be adjusted according to taste;7. passing through addition pure water or food With the alcoholic strength of alcohol adjustment alcoholic drink mixed with fruit juice.
CN201910066450.3A 2019-01-24 2019-01-24 A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar Pending CN109694805A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910066450.3A CN109694805A (en) 2019-01-24 2019-01-24 A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910066450.3A CN109694805A (en) 2019-01-24 2019-01-24 A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar

Publications (1)

Publication Number Publication Date
CN109694805A true CN109694805A (en) 2019-04-30

Family

ID=66234336

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910066450.3A Pending CN109694805A (en) 2019-01-24 2019-01-24 A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar

Country Status (1)

Country Link
CN (1) CN109694805A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110205228A (en) * 2019-06-24 2019-09-06 赵为兴 A kind of fructus cannabis coffee alcoholic drink mixed with fruit juice formula and preparation method thereof for alleviating gout
CN113528282A (en) * 2021-08-10 2021-10-22 赵为兴 Formula and preparation method of red butter liqueur
CN115232699A (en) * 2022-03-31 2022-10-25 赵为兴 Fructus cannabis beverage and preparation method thereof

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1536066A (en) * 2003-04-07 2004-10-13 尹凤琴 Health-care liquor with functions of reducing blood sugar, reducing blood fat and promoting urination
CN1552839A (en) * 2003-06-01 2004-12-08 高景曦 Nano modified red common stonecrop health-care wine
JP2009005607A (en) * 2007-06-27 2009-01-15 Nara Prefecture Pueraria lobata liquor and method for producing the same
CN101967439A (en) * 2010-10-29 2011-02-09 重庆康友葛根专业合作社 Vine root health wine and preparation method thereof
CN102266484A (en) * 2011-07-26 2011-12-07 南京正宽医药科技有限公司 Pueraria wine capable of preventing and treating cardiovascular and cerebrovascular diseases as well as preparation method and application thereof
CN102604797A (en) * 2011-01-20 2012-07-25 云南龙润药业有限公司 Beautifying and detoxifying wine and its preparation method
CN102994342A (en) * 2012-11-23 2013-03-27 吴江永祥酒精制造有限公司 Mulberry juice wine and preparation method thereof
CN103468505A (en) * 2013-09-09 2013-12-25 刘鹏 Yellow wine with health-care effect on patients with diabetes
CN104479946A (en) * 2014-10-23 2015-04-01 苏州垣梦新能源环保科技有限公司 Method for preparing nutrient alcoholic drink mixed with fruit juice from hibiscus esculentus-fungus-algae plant composition
CN105018312A (en) * 2015-06-26 2015-11-04 刘伟 Strawberry health preserving liqueur and preparation method thereof
CN107586682A (en) * 2017-10-23 2018-01-16 广西巴马响泉食品有限公司 A kind of brew method of alcoholic drink mixed with fruit juice
CN107898826A (en) * 2017-11-01 2018-04-13 云南谷益美农业开发有限公司 The preparation method of the numb medicinal extract of fire containing cannabidiol
CN108524631A (en) * 2018-03-12 2018-09-14 安徽海神寿***业有限公司 It is a kind of mix peach kernel, fructus cannabis ease constipation extract powder production method

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1536066A (en) * 2003-04-07 2004-10-13 尹凤琴 Health-care liquor with functions of reducing blood sugar, reducing blood fat and promoting urination
CN1552839A (en) * 2003-06-01 2004-12-08 高景曦 Nano modified red common stonecrop health-care wine
JP2009005607A (en) * 2007-06-27 2009-01-15 Nara Prefecture Pueraria lobata liquor and method for producing the same
CN101967439A (en) * 2010-10-29 2011-02-09 重庆康友葛根专业合作社 Vine root health wine and preparation method thereof
CN102604797A (en) * 2011-01-20 2012-07-25 云南龙润药业有限公司 Beautifying and detoxifying wine and its preparation method
CN102266484A (en) * 2011-07-26 2011-12-07 南京正宽医药科技有限公司 Pueraria wine capable of preventing and treating cardiovascular and cerebrovascular diseases as well as preparation method and application thereof
CN102994342A (en) * 2012-11-23 2013-03-27 吴江永祥酒精制造有限公司 Mulberry juice wine and preparation method thereof
CN103468505A (en) * 2013-09-09 2013-12-25 刘鹏 Yellow wine with health-care effect on patients with diabetes
CN104479946A (en) * 2014-10-23 2015-04-01 苏州垣梦新能源环保科技有限公司 Method for preparing nutrient alcoholic drink mixed with fruit juice from hibiscus esculentus-fungus-algae plant composition
CN105018312A (en) * 2015-06-26 2015-11-04 刘伟 Strawberry health preserving liqueur and preparation method thereof
CN107586682A (en) * 2017-10-23 2018-01-16 广西巴马响泉食品有限公司 A kind of brew method of alcoholic drink mixed with fruit juice
CN107898826A (en) * 2017-11-01 2018-04-13 云南谷益美农业开发有限公司 The preparation method of the numb medicinal extract of fire containing cannabidiol
CN108524631A (en) * 2018-03-12 2018-09-14 安徽海神寿***业有限公司 It is a kind of mix peach kernel, fructus cannabis ease constipation extract powder production method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吴克刚等: "《食品微胶囊技术》", 31 July 2006, 中国轻工业出版社 *
王镜岩等: "《生物化学》", 30 September 2002, 高等教育出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110205228A (en) * 2019-06-24 2019-09-06 赵为兴 A kind of fructus cannabis coffee alcoholic drink mixed with fruit juice formula and preparation method thereof for alleviating gout
CN113528282A (en) * 2021-08-10 2021-10-22 赵为兴 Formula and preparation method of red butter liqueur
CN115232699A (en) * 2022-03-31 2022-10-25 赵为兴 Fructus cannabis beverage and preparation method thereof

Similar Documents

Publication Publication Date Title
CN104435775B (en) A kind of Traditional Chinese medicinal health-care wine and preparation method thereof
CN102988638B (en) Cyclocarya paliurus blood-lipid and blood-sugar reducing health-care tea and preparation method thereof
CN103749817A (en) Jasmine tea and preparation method thereof
CN104186793B (en) A kind of health tea and preparation method thereof
CN103053748A (en) Kudzu vine root fat-reducing sugar-reducing health-care tea and preparation method thereof
CN109694805A (en) A kind of formula and preparation method thereof of the friendly tender tea leaves alcoholic drink mixed with fruit juice of sugar
CN108578544A (en) A kind of Chinese medicine composition and the preparation method and application thereof with blood sugar reducing function
CN107751993A (en) A kind of antifatigue cream taste and preparation method thereof
CN110205228A (en) A kind of fructus cannabis coffee alcoholic drink mixed with fruit juice formula and preparation method thereof for alleviating gout
CN110051815A (en) A kind of auxiliary hyperglycemic food ball and preparation method thereof
CN104474472B (en) Buccal lozenge of lectuce tea and its production method with three high drop effect
CN107019136A (en) A kind of solid beverage with effect of lowering blood sugar and preparation method thereof
KR101647917B1 (en) Chestnut medicinal wine having extract of stachys sieboldii and methods for manufacturing thereof
CN106362007A (en) Traditional Chinese medicine composition containing dendrobium huoshanense and achieving glucose lowering effect and preparation method thereof
CN105077467A (en) Health-care abalone-sea cucumber beverage with blood sugar-reducing function
CN105219602B (en) A kind of hypoglycemic root of kudzu vine yellow rice wine and preparation method thereof
CN108260682A (en) A kind of hypoglycemic, reducing blood lipid and the health protection tea of blood pressure lowering
CN106692760A (en) Golden flower wine formula for preventing diabetes and preparation method thereof
CN106421491A (en) Formula of radix helicteris oral liquid with blood glucose reducing effect and preparation method
CN107125521A (en) A kind of fermenting plant beverage for improving sleep and preparation method thereof
CN105433372A (en) Stomach-warming and intestine-moistening coix-seed paste as well as preparation method thereof
CN110157572A (en) Functional Golden flower wine and preparation method thereof
CN104606570A (en) Consumptive thirst tea substitute drink suitable for diabetes patients and preparation method of consumptive thirst tea substitute drink
KR101118047B1 (en) An oriental drink comprising a phyllostachys bambusoides, a barley sprout, a yacon strawberry and a mulberry leaves
CN108967787A (en) A kind of India's ivy gourd leaf beverage and preparation method thereof with effect of lowering blood sugar

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190430