CN109668873A - 一种活载体疫苗活性检测装置及其使用方法 - Google Patents
一种活载体疫苗活性检测装置及其使用方法 Download PDFInfo
- Publication number
- CN109668873A CN109668873A CN201811478305.8A CN201811478305A CN109668873A CN 109668873 A CN109668873 A CN 109668873A CN 201811478305 A CN201811478305 A CN 201811478305A CN 109668873 A CN109668873 A CN 109668873A
- Authority
- CN
- China
- Prior art keywords
- liquid
- live vector
- vector vaccine
- vaccinogen
- storage cylinder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940023832 live vector-vaccine Drugs 0.000 title claims abstract description 103
- 230000000694 effects Effects 0.000 title claims abstract description 74
- 238000000034 method Methods 0.000 title claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 274
- 238000001514 detection method Methods 0.000 claims abstract description 82
- 241000894006 Bacteria Species 0.000 claims abstract description 19
- 229960005486 vaccine Drugs 0.000 claims abstract description 16
- 238000006243 chemical reaction Methods 0.000 claims abstract description 8
- 239000012530 fluid Substances 0.000 claims description 41
- 238000012546 transfer Methods 0.000 claims description 40
- 239000000203 mixture Substances 0.000 claims description 9
- 238000007789 sealing Methods 0.000 claims description 9
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims description 8
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims description 8
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 7
- 229960001484 edetic acid Drugs 0.000 claims description 7
- 230000008569 process Effects 0.000 claims description 6
- 238000012545 processing Methods 0.000 claims description 5
- 150000003950 cyclic amides Chemical class 0.000 claims description 4
- 230000000855 fungicidal effect Effects 0.000 claims description 4
- 238000002329 infrared spectrum Methods 0.000 claims description 4
- 235000014676 Phragmites communis Nutrition 0.000 claims description 3
- 238000004925 denaturation Methods 0.000 claims description 3
- 230000036425 denaturation Effects 0.000 claims description 3
- 201000010099 disease Diseases 0.000 claims description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 3
- 238000010494 dissociation reaction Methods 0.000 claims description 3
- 230000005593 dissociations Effects 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims description 3
- 238000005286 illumination Methods 0.000 claims description 3
- 230000003595 spectral effect Effects 0.000 claims description 3
- 238000000870 ultraviolet spectroscopy Methods 0.000 claims description 3
- LCCNCVORNKJIRZ-UHFFFAOYSA-N parathion Chemical compound CCOP(=S)(OCC)OC1=CC=C([N+]([O-])=O)C=C1 LCCNCVORNKJIRZ-UHFFFAOYSA-N 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000002779 inactivation Effects 0.000 abstract description 16
- 108090000623 proteins and genes Proteins 0.000 abstract description 10
- 238000005516 engineering process Methods 0.000 abstract description 9
- 102000004169 proteins and genes Human genes 0.000 abstract description 9
- 238000003556 assay Methods 0.000 abstract description 7
- 229940031551 inactivated vaccine Drugs 0.000 description 6
- 241000700605 Viruses Species 0.000 description 5
- 230000009471 action Effects 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 2
- 230000001900 immune effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241001465805 Nymphalidae Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 108010008038 Synthetic Vaccines Proteins 0.000 description 1
- 241000700618 Vaccinia virus Species 0.000 description 1
- 241000700647 Variola virus Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 230000030741 antigen processing and presentation Effects 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001502 gel electrophoresis Methods 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229940124551 recombinant vaccine Drugs 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Engineering & Computer Science (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811478305.8A CN109668873B (zh) | 2018-12-05 | 2018-12-05 | 一种活载体疫苗活性检测装置及其使用方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811478305.8A CN109668873B (zh) | 2018-12-05 | 2018-12-05 | 一种活载体疫苗活性检测装置及其使用方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109668873A true CN109668873A (zh) | 2019-04-23 |
CN109668873B CN109668873B (zh) | 2021-03-16 |
Family
ID=66144119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811478305.8A Active CN109668873B (zh) | 2018-12-05 | 2018-12-05 | 一种活载体疫苗活性检测装置及其使用方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109668873B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113030465A (zh) * | 2021-03-03 | 2021-06-25 | 广州洛民塑料有限公司 | 一种全自动疫苗送检装置 |
Citations (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN200945432Y (zh) * | 2006-04-20 | 2007-09-12 | 周东海 | 活塞式自清洁反应器与搅拌釜 |
CN201837555U (zh) * | 2010-10-02 | 2011-05-18 | 大庆油田有限责任公司 | 可搅拌式配样器 |
CN102323409A (zh) * | 2011-01-17 | 2012-01-18 | 广东现代农业集团研究院有限公司 | 一种病毒感染检测方法 |
CN102854160A (zh) * | 2012-08-31 | 2013-01-02 | 贵州泰邦生物制品有限公司 | 紫外分光光度法检测人免疫球蛋白Fc段生物学活性的方法 |
EP2540764A2 (en) * | 2011-06-30 | 2013-01-02 | Korea Institute of Science and Technology | Poly(organophosphazene) composition for biomaterials |
US20130028931A1 (en) * | 2011-07-29 | 2013-01-31 | Boehringer Ingelheim Vetmedica Gmbh | Novel prrs virus inducing type i interferon in susceptible cells |
EP2554549A1 (en) * | 2011-08-02 | 2013-02-06 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Oligosaccharides and oligosaccharides-protein conjugates derived from clostridium difficile polysaccharide PS-I, methods of synthesis and uses thereof, in particular as vaccines and diagnostic tools |
CN202844257U (zh) * | 2012-10-30 | 2013-04-03 | 无锡耐思生物科技有限公司 | 一种混药预灌封注射器 |
KR20130119378A (ko) * | 2012-04-23 | 2013-10-31 | 주식회사 나노브릭 | 타겟 물질 검출 방법 및 장치 |
CN103694348A (zh) * | 2013-12-10 | 2014-04-02 | 刘聚祥 | 一种治疗猪病毒性腹泻生物制剂的制备和应用方法 |
CN104198357A (zh) * | 2014-09-24 | 2014-12-10 | 广东省农业科学院动物卫生研究所 | 流式细胞术方法在疫苗生产实时监测中的应用 |
CN104198669A (zh) * | 2014-09-02 | 2014-12-10 | 蒋建江 | 利用微量溶血分光光度法测定气管炎疫苗免疫活性的方法 |
CN104698166A (zh) * | 2015-03-17 | 2015-06-10 | 山东省农业科学院畜牧兽医研究所 | 一种灭活疫苗灭活程度的检测方法 |
CN104736172A (zh) * | 2012-05-09 | 2015-06-24 | 康特拉费克特公司 | 针对***的噬菌体溶素和抗生素组合 |
US9091251B1 (en) * | 2011-07-14 | 2015-07-28 | Boise State University | Actuation method and apparatus, micropump, and PCR enhancement method |
US20160129097A1 (en) * | 2014-11-06 | 2016-05-12 | Jeremy Delk | Method of processing a veterinary tumor vaccine and a veterinary tumor vaccine processing kit |
CN205398608U (zh) * | 2016-03-08 | 2016-07-27 | 山东富优生命科学有限公司 | 一种快速提取全血基因组设备 |
WO2016118780A1 (en) * | 2015-01-21 | 2016-07-28 | Fred Hutchinson Cancer Research Center | Point-of-care and/or portable platform for gene therapy |
CN106267419A (zh) * | 2016-07-01 | 2017-01-04 | 翁炳焕 | Hiv免疫净化器 |
CN106282388A (zh) * | 2016-10-18 | 2017-01-04 | 中国农业大学 | 基于环介导等温扩增消光技术的转基因油菜gt73检测方法 |
CN205895264U (zh) * | 2016-08-02 | 2017-01-18 | 上海力行工程技术发展有限公司 | 一种盾构机注浆防堵构件 |
US20170151346A1 (en) * | 2015-07-15 | 2017-06-01 | Suzhou M-Conj Biotech Co., Ltd. | Disulfur bridge linkers for conjugation of a cell-binding molecule |
CN107206165A (zh) * | 2014-12-24 | 2017-09-26 | 弗罗桑医疗设备公司 | 用于保持并混合第一和第二物质的注射器 |
CN107304419A (zh) * | 2016-04-22 | 2017-10-31 | 中国农业科学院兰州兽医研究所 | 一种抗猪瘟病毒VHH抗体的酵母cDNA文库及其构建方法和用途 |
CN107685414A (zh) * | 2017-09-30 | 2018-02-13 | 京华派克邯郸机械科技有限公司 | 一种混合装置 |
CN108138099A (zh) * | 2015-06-24 | 2018-06-08 | 阿德瓦希斯公司 | 用于个性化的基于递送载体的免疫疗法的制造装置和方法 |
CN207574373U (zh) * | 2017-11-22 | 2018-07-06 | 陈洪玉 | 具有环保节约特点的药液自动混合喷雾器 |
CN207640751U (zh) * | 2017-05-22 | 2018-07-24 | 胡茂伟 | 一种医院麻醉科手术局部麻醉用注射器 |
CN207666937U (zh) * | 2017-05-18 | 2018-07-31 | 李一凡 | 一种疫苗接种注射器 |
CN207972459U (zh) * | 2017-11-06 | 2018-10-16 | 林国亮 | 走珠式修正液笔头 |
CN207980654U (zh) * | 2017-12-28 | 2018-10-19 | 山西阳光中天医疗器械有限公司 | 一种用于分离脂肪混合液的滤油装置 |
CN108918444A (zh) * | 2018-07-23 | 2018-11-30 | 哈尔滨理工大学 | 基于紫外-可见光谱技术的牛乳中大肠杆菌的检测方法 |
-
2018
- 2018-12-05 CN CN201811478305.8A patent/CN109668873B/zh active Active
Patent Citations (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN200945432Y (zh) * | 2006-04-20 | 2007-09-12 | 周东海 | 活塞式自清洁反应器与搅拌釜 |
CN201837555U (zh) * | 2010-10-02 | 2011-05-18 | 大庆油田有限责任公司 | 可搅拌式配样器 |
CN102323409A (zh) * | 2011-01-17 | 2012-01-18 | 广东现代农业集团研究院有限公司 | 一种病毒感染检测方法 |
EP2540764A2 (en) * | 2011-06-30 | 2013-01-02 | Korea Institute of Science and Technology | Poly(organophosphazene) composition for biomaterials |
US9091251B1 (en) * | 2011-07-14 | 2015-07-28 | Boise State University | Actuation method and apparatus, micropump, and PCR enhancement method |
US20130028931A1 (en) * | 2011-07-29 | 2013-01-31 | Boehringer Ingelheim Vetmedica Gmbh | Novel prrs virus inducing type i interferon in susceptible cells |
EP2554549A1 (en) * | 2011-08-02 | 2013-02-06 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Oligosaccharides and oligosaccharides-protein conjugates derived from clostridium difficile polysaccharide PS-I, methods of synthesis and uses thereof, in particular as vaccines and diagnostic tools |
KR20130119378A (ko) * | 2012-04-23 | 2013-10-31 | 주식회사 나노브릭 | 타겟 물질 검출 방법 및 장치 |
CN104736172A (zh) * | 2012-05-09 | 2015-06-24 | 康特拉费克特公司 | 针对***的噬菌体溶素和抗生素组合 |
CN102854160A (zh) * | 2012-08-31 | 2013-01-02 | 贵州泰邦生物制品有限公司 | 紫外分光光度法检测人免疫球蛋白Fc段生物学活性的方法 |
CN202844257U (zh) * | 2012-10-30 | 2013-04-03 | 无锡耐思生物科技有限公司 | 一种混药预灌封注射器 |
CN103694348A (zh) * | 2013-12-10 | 2014-04-02 | 刘聚祥 | 一种治疗猪病毒性腹泻生物制剂的制备和应用方法 |
CN104198669A (zh) * | 2014-09-02 | 2014-12-10 | 蒋建江 | 利用微量溶血分光光度法测定气管炎疫苗免疫活性的方法 |
CN104198357A (zh) * | 2014-09-24 | 2014-12-10 | 广东省农业科学院动物卫生研究所 | 流式细胞术方法在疫苗生产实时监测中的应用 |
US20160129097A1 (en) * | 2014-11-06 | 2016-05-12 | Jeremy Delk | Method of processing a veterinary tumor vaccine and a veterinary tumor vaccine processing kit |
CN107206165A (zh) * | 2014-12-24 | 2017-09-26 | 弗罗桑医疗设备公司 | 用于保持并混合第一和第二物质的注射器 |
WO2016118780A1 (en) * | 2015-01-21 | 2016-07-28 | Fred Hutchinson Cancer Research Center | Point-of-care and/or portable platform for gene therapy |
CN104698166A (zh) * | 2015-03-17 | 2015-06-10 | 山东省农业科学院畜牧兽医研究所 | 一种灭活疫苗灭活程度的检测方法 |
CN108138099A (zh) * | 2015-06-24 | 2018-06-08 | 阿德瓦希斯公司 | 用于个性化的基于递送载体的免疫疗法的制造装置和方法 |
US20170151346A1 (en) * | 2015-07-15 | 2017-06-01 | Suzhou M-Conj Biotech Co., Ltd. | Disulfur bridge linkers for conjugation of a cell-binding molecule |
CN205398608U (zh) * | 2016-03-08 | 2016-07-27 | 山东富优生命科学有限公司 | 一种快速提取全血基因组设备 |
CN107304419A (zh) * | 2016-04-22 | 2017-10-31 | 中国农业科学院兰州兽医研究所 | 一种抗猪瘟病毒VHH抗体的酵母cDNA文库及其构建方法和用途 |
CN106267419A (zh) * | 2016-07-01 | 2017-01-04 | 翁炳焕 | Hiv免疫净化器 |
CN205895264U (zh) * | 2016-08-02 | 2017-01-18 | 上海力行工程技术发展有限公司 | 一种盾构机注浆防堵构件 |
CN106282388A (zh) * | 2016-10-18 | 2017-01-04 | 中国农业大学 | 基于环介导等温扩增消光技术的转基因油菜gt73检测方法 |
CN207666937U (zh) * | 2017-05-18 | 2018-07-31 | 李一凡 | 一种疫苗接种注射器 |
CN207640751U (zh) * | 2017-05-22 | 2018-07-24 | 胡茂伟 | 一种医院麻醉科手术局部麻醉用注射器 |
CN107685414A (zh) * | 2017-09-30 | 2018-02-13 | 京华派克邯郸机械科技有限公司 | 一种混合装置 |
CN207972459U (zh) * | 2017-11-06 | 2018-10-16 | 林国亮 | 走珠式修正液笔头 |
CN207574373U (zh) * | 2017-11-22 | 2018-07-06 | 陈洪玉 | 具有环保节约特点的药液自动混合喷雾器 |
CN207980654U (zh) * | 2017-12-28 | 2018-10-19 | 山西阳光中天医疗器械有限公司 | 一种用于分离脂肪混合液的滤油装置 |
CN108918444A (zh) * | 2018-07-23 | 2018-11-30 | 哈尔滨理工大学 | 基于紫外-可见光谱技术的牛乳中大肠杆菌的检测方法 |
Non-Patent Citations (6)
Title |
---|
LIU B: "Characterization and immunological activity of different forms of recom⁃binant secreted Hc of botulinum neurotoxin serotype B products expressed in yeast", 《SCI REP》 * |
WILLIAM FOUNTAIN: "Near-infrared spectroscopy for the determination of testoterone in thin-film composits", 《JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS》 * |
丁军涛: "山羊痘病毒 P32 抗原基因口服活载体 DNA", 《中国兽医科学》 * |
崔淑芬: "《实验动物学(第4版)》", 31 January 2013, 第二中医大学出版社 * |
彭宜: "利用RT-LAMP可视化检测技术检测H1亚型", 《病毒学报》 * |
陈博阳: "B型肉毒毒素重组Hc亚单位疫苗的免疫原性研究", 《生物技术通讯》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113030465A (zh) * | 2021-03-03 | 2021-06-25 | 广州洛民塑料有限公司 | 一种全自动疫苗送检装置 |
Also Published As
Publication number | Publication date |
---|---|
CN109668873B (zh) | 2021-03-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106434330B (zh) | 一种基于高效液滴微反应器的绝对定量数字核酸分析*** | |
TWI734929B (zh) | 多色螢光激發及偵測裝置及其核酸分析設備應用 | |
CN109668873A (zh) | 一种活载体疫苗活性检测装置及其使用方法 | |
CN105092543A (zh) | 一种便携式荧光定量pcr检测仪 | |
CN110231275B (zh) | 一种基于流式细胞术检测nk细胞杀伤活性的方法 | |
CN102838993A (zh) | 一种氧化乐果农药的荧光纳米CdSe量子点探针及其应用 | |
RU2014144000A (ru) | Проточная камера для флуорометра реального времени | |
CN104391050A (zh) | 化妆品中38种限用着色剂同时检测的方法 | |
CN105277697A (zh) | 一种测定血液中循环上皮肿瘤细胞数量的方法 | |
CN109141989A (zh) | 页岩解析气自动定量采样装置 | |
CN105246190B (zh) | 标准光源及采用该标准光源的化学发光免疫分析仪 | |
CN108531175B (zh) | 一种近红外荧光粉及其制备方法和应用 | |
CN204462091U (zh) | 一种捕获植物挥发性物质的气流式液相微富集装置 | |
CN102539573A (zh) | Uplc-tqd联用技术同时测定组织引流液中万古霉素与妥布霉素含量的方法 | |
CN105319187B (zh) | 一种快速检测血液thc的设备 | |
CN111413149B (zh) | 一种生物科技药剂制品检测用取样装置 | |
CN106370637A (zh) | 一种针对葡萄糖的量子点气凝胶微传感器、其量子点气凝胶的制备方法及其应用 | |
CN102944539B (zh) | 基于量子点共振能量转移的mgmt活性检测试剂盒及方法 | |
CN205192951U (zh) | 一种快速检测血液thc的设备 | |
CN109142303A (zh) | 一种检测汞离子的方法 | |
CN214142350U (zh) | 一种核酸检测***的预装层与提取层连接结构 | |
WO2022203792A1 (en) | Closed-system sorting flow cytometer adapters and methods of use thereof | |
CN103594625B (zh) | 基于有机p-n结的紫外探测器件及使用该器件的紫外图像探测器 | |
CN221078473U (zh) | 一种微塑料拉曼检测装置 | |
CN217586902U (zh) | 一种基于傅里叶红外光谱的气体检测装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information |
Inventor after: Wang Chunbo Inventor after: Wu Jinfeng Inventor after: Liu Wei Inventor after: Xing Fengjiang Inventor before: Xing Fengjiang |
|
CB03 | Change of inventor or designer information | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20210301 Address after: 266000 north of Xinyue Road, west of torch Branch Road, high tech Industrial Development Zone, Qingdao City, Shandong Province Applicant after: SHANDONG HENGYE BIOTECHNOLOGY Co.,Ltd. Address before: 136000 2-11-2, No.57, Pingnan street, Tiedong District, Siping City, Jilin Province Applicant before: Xing Fengjiang |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant |