CN109652975B

CN109652975B - Preparation method of antibacterial auxiliary material

Info

Publication number: CN109652975B
Application number: CN201811452909.5A
Authority: CN
Inventors: 陈钦旺
Original assignee: Lishui Tianshun Guide Rail Manufacturing Co ltd
Current assignee: LISHUI TIANSHUN GUIDE RAIL MANUFACTURING Co.,Ltd.
Priority date: 2017-06-22
Filing date: 2017-06-22
Publication date: 2021-06-08
Anticipated expiration: 2037-06-22
Also published as: CN109577018B; CN109629119B; CN109629119A; CN109652975A; CN109629224A; CN107268178A; CN109371566A; CN109371566B; CN107268178B; CN109577018A; CN109629224B

Abstract

A method for preparing antibacterial adjuvant improves hydrophilicity of fiber web by plasma treatment, so that antibacterial agent is more easily absorbed by fiber web. The treatment of the fiber web by the electric field can lead the fiber monomers on the fiber web to stand up, which is more beneficial to the permeation and embedding of the antibacterial agent; the direction of the magnetic force line in the magnetic field can be parallel to the running direction of the fiber web and can also be vertical to the running direction of the fiber web, after the fiber web passes through the magnetic field, the nano magnetic particles applied to the fiber web generate an orientation effect under the action of an external magnetic field, so that the orientation of the magnetic particles is more regular, the auxiliary material has a magnetic field effect in a certain direction due to the regularly oriented magnetic particles, the blood microcirculation at the position where the auxiliary material is pasted can be improved, and the healing of a wound and the tissue regeneration are promoted.

Description

Preparation method of antibacterial auxiliary material

Technical Field

The invention relates to a preparation method of a medical material, in particular to a preparation method of an antibacterial auxiliary material.

Background

Plasma is an ionized gas of a fourth state of matter different from solid, liquid, and gaseous. 99% of the material in the universe exists in the form of plasma. Macroscopically, the plasma is electrically neutral, however, the plasma contains free charges and is electrically conductive. Plasma technology is an emerging technology with surprising potential applications. In the medical field, plasma treatment techniques can be used for wound healing, tumor therapy, tissue engineering, equipment disinfection and surgical devices. In the textile field, plasmas can graft new functional groups onto the surface of textile substrates and modify the surface properties of polymers with the aid of reactive gases (e.g. oxygen, nitrogen, ammonia or water vapor). In the electronics industry, plasmas are used in the fabrication of electronic devices for bonding, cleaning, and semiconductor manufacturing. With the aging of the plasma technology, the application prospect is wider and wider.

Plasma was named by langmuir in 1928, and dates back to williamus kluk in 1879 at the earliest time, which confirmed the presence of a substance in the discharge tube during gas discharge experiments) plasma state "the states of a substance can be transformed into one another under certain conditions; while different states of aggregation of the substance correspond to different degrees of order of the arrangement of the constituent particles of the substance. Thus, the transformation between states of matter is, in effect, a process that alters the degree of order of matter. It is recognized from scientific experiments and production practice that as long as the kinetic energy of electrons in each ion exceeds the ionization energy of atoms, electrons will be unbound from atoms and become free electrons, while atoms become positively charged ions due to the loss of electrons, and the process becomes ionization. When a sufficient number of atoms in the gas are ionized, the ionized gas is not the original gas but is converted into a new state of matter, the so-called plasma state. Any ordinary gas composed of neutral particles can become plasma as long as the outside supplies energy to raise the temperature sufficiently. Experiments show that even if 0.1% of gas in common gas is ionized, the ionized gas has good plasma property; if 1% of gas is ionized, then the plasma becomes ideal electric conductor' plasma which is composed of a large amount of free electrons and high-energy ions and represents quasi-electroneutral ionized gas as a whole, so that the property of the plasma is greatly different from that of common gas, particles in the common gas mainly carry out disordered thermal motion, and in the plasma, the high-energy particles generate plasma oscillation besides thermal motion, and particularly under the condition that an external magnetic field exists, the plasma motion is influenced and dominated by the magnetic field, which is an important difference between the plasma and the common gas.

Plasma discharge is required to be performed under different pressure conditions, and thus is classified into low-pressure plasma and normal-pressure plasma according to the working gas pressure. The low-pressure plasma needs to be realized under the condition of low pressure or high vacuum, and the normal-pressure plasma refers to a discharge mode in which plasma is generated under the condition of atmospheric pressure, so that the limitation existing in the application of the low-pressure plasma is overcome, and the continuous processing and modification of the material can be realized. The energy and quantity of particles excited by the atmospheric pressure plasma are different from those of the low-pressure plasma, but the effect of a large amount of active substances generated by the atmospheric pressure plasma on the material is similar to that of the low-pressure plasma.

In order to generate plasma, sufficient energy must be applied to the gas, and thus the plasma is classified into plasma including Direct Current (DC), Radio Frequency (RF), Low Frequency (LF), and Microwave (MW) according to an energy source.

With the increasing demand of modern society for functional fiber materials, cotton fibers need to have not only their most basic characteristics but also environmentally friendly functions such as self-cleaning, antibacterial, antifouling, etc. However, cotton fabrics contain a large number of hydroxyl groups in their structure, so they are easily wetted and stained by liquids, and many basic researches and practical applications are devoted to developing functional cotton fabrics with special wettability. At present, people introduce the super-hydrophilic self-cleaning function of lotus leaves into the field of textiles, and prepare super-hydrophilic cotton fabrics by increasing the surface roughness of the fabrics and reducing the surface free energy of the fabrics through chemical or geometric surface modification. Generally, fluorine-containing compounds are needed to prepare the super-hydrophilic cotton fabric, but long-chain fluorine-containing compounds are generally harmful to human bodies and easily cause environmental pollution. Moreover, the chemical bond acting force between the monomer and the cotton fabric is weak, so that the fastness of the fabric subjected to water repellent finishing is low. It has been found that cyclic siloxane tetramethyltetravinylcyclotetrasiloxane not only increases the water repellency of finished fabrics, but also increases the softness of the fabric. In the plasma graft copolymerization method, the monomer polymer and the fiber are combined by covalent bonds, thereby being beneficial to improving the washing fastness of the fabric. Therefore, the paper combines the plasma technology with fluorine-free tetramethyltetravinylcyclotetrasiloxane and octadecyl methacrylate monomers to develop the cotton textile with super-hydrophilic function.

Ordinary cotton is composed of cotton fiber materials, fungi are easily absorbed and bred on the fibers, and the ordinary cotton has no bacteriostatic and bactericidal effects and only has the function of shielding bacteria.

The antibacterial cotton is obtained by carrying out antibacterial finishing on common cotton. The finishing technology endows the cotton gauze material with antibacterial performance, improves the antibacterial capability of the material, and enables the material to resist or kill bacteria while shielding the bacteria. Therefore, the wound infection rate of the wound wrapped by cotton can be effectively reduced.

The existing antibacterial cotton is mainly divided into two categories according to different antibacterial finishing agents: organic antibacterial agent finished cotton and inorganic antibacterial agent finished cotton. The organic antibacterial agent finished cotton has the defects of single antibacterial type, poor safety, easy generation of drug resistance of microorganisms to the organic antibacterial agent, poor chemical stability, poor heat resistance and the like. The inorganic antibacterial agent finished cotton overcomes the defects, and has the advantages of broad-spectrum antibacterial, high use safety, strong chemical stability, good heat resistance and the like.

In the existing inorganic antibacterial agent finished cotton, the gauze finished by the silver antibacterial agent is more, and the molecular structure of the finishing agent does not have a group which generates acting force with cotton cellulose molecules, so that the antibacterial agents have the problems of low binding fastness with cotton fiber gauze and poor water washing resistance. The existing finishing process of silver-based antibacterial finishing gauze is mainly a coating method, namely, a proper amount of antibacterial agent is added into a coating agent to coat the surface of a fabric, and then a layer of coating is formed on the surface of the fabric through drying and necessary heat treatment. Most of the medical antibacterial gauze processed by the method is a single-side coating, and the area with antibacterial capability is concentrated on one side of the fabric and only exists on the surface of the fabric. Meanwhile, the antibacterial cotton product finished by the coating method is influenced by the finishing process, and the permeability and the handfeel softness of the cotton are poorer than those of the common cotton.

Disclosure of Invention

The invention aims to provide a preparation method of an auxiliary material with better antibacterial property.

In order to achieve the purpose, the invention adopts the following technical scheme:

a preparation method of an antibacterial auxiliary material comprises the following steps:

1): mixing and opening fiber raw materials, and uniformly mixing the fiber raw materials through an automatic cotton mixer; the mixed fiber raw materials are mixed by a pre-opener, uniformly opened and delivered to the next procedure by a cotton delivery fan;

2): the raw materials conveyed by the pre-opener are further refined by the main opener to ensure that the raw materials are opened more uniformly, and then are conveyed to a cotton storage bin of a cotton feeding machine by a cotton conveying fan;

3): the cotton feeder feeds the loosened and mixed fiber raw materials into a carding machine quantitatively and uniformly; carding the fiber raw material output and formed by the cotton feeder into a web by a carding machine to form a uniform single-layer fiber web;

4): the lapping machine uniformly lays the single-layer fiber webs output by the carding machine to half of the required thickness, and after applying the nano magnetic particles between every two layers of fiber webs, the lapping is continued until the required thickness and width are reached, and the single-layer fiber webs are continuously conveyed to the next procedure;

5): longitudinally stretching the fiber web stacked by the lapping machine through a multi-roller drafting machine to ensure that the fiber web has more tension and elasticity, and then conveying the fiber web to a plasma processing part to ensure that the fiber web is easier to bond with an antibacterial agent applied in the subsequent antibacterial processing process;

6): carrying out antibacterial agent spraying treatment on the fiber web conveyed by the multi-roller drafting machine, respectively spraying antibacterial agents on the front and back surfaces of the fiber web by a front spraying box and a back spraying box, vacuumizing the front spraying box and the back spraying box to keep a negative pressure state, so that the antibacterial agents are more easily impregnated into the fiber web;

7): leading the fiber web which is not dried after being sprayed with the antibacterial agent to pass through a first electric field treatment area under the guidance of a first guide roller set;

8): the fiber web treated in the first electric field treatment area enters a low-temperature oven for pre-drying, the surface layer of the antibacterial agent coating is preliminarily shaped and dried, and the inner layer of the antibacterial agent is still in a semi-solidified flowable state;

9): and leading the pre-dried fiber web to pass through the first magnetic field treatment area under the guide of the second guide roller group, and performing orientation treatment on the nano magnetic particles applied to the fibers under the action of an external magnetic field.

10): sending the fiber web subjected to the first magnetic field treatment into a dryer for drying and shaping; cutting edges, cutting and coiling the shaped product through a rolling edge cutter;

further, the fiber raw materials in the step 1) comprise 50-80% of antibacterial fiber, 20-40% of superfine thermal fiber and 30-40% of antibacterial silver ion fiber.

Further, the fiber raw materials in the step 1) comprise 50 antibacterial fibers, 20 superfine thermal fibers and 30 antibacterial silver ion fibers.

Further, the process of the carding machine in the step 3) is set as follows: the cylinder speed is 1000-.

Further, the lower layer of the oven of the low-temperature oven for pre-drying in the step 8) is 40-60 ℃, the middle layer is 60-80 ℃ and the upper layer is 80-100 ℃; the temperature of the first region of the dryer performing the drying in the step 10) is 120-140 ℃, the temperature of the second region is 140-160 ℃, and the temperature of the third region is 160-180 ℃.

Further, the step 6)

The antibacterial agent is prepared by mixing 80% of pure acrylic polymer emulsion, 1% of nano titanium dioxide powder and a biological antibacterial agent.

Further, the plasma processing technology in the step 5) is that the frequency of a high-voltage power supply is 500Hz to 800Hz, the pulse width is 2 mus to 10 mus, the voltage amplitude is minus 40kV to minus 60kV, and the processing time is 40min to 60 min.

Further, the first electric field in the step 7) is a capacitor electric field; the first magnetic field in the step 9) is a magnetic field generated by an electromagnetic coil, and the direction of magnetic lines in the magnetic field can be parallel to the running direction of the fiber web or perpendicular to the running direction of the fiber web.

The invention has the beneficial effects that: through adding certain nanometer titanium dioxide powder in the antibacterial agent, can absorb ultraviolet light, a large amount of hydroxyl free radicals that the silver ion in the antibiotic silver ion master batch primary fiber of nanometer passes through the photocatalytic reaction under the irradiation of ultraviolet light produces, can assault the microbial cell simultaneously through active oxygen group and silver ion from this, destroy cell wall and intracellular enzyme gene, thereby bactericidal effect has been improved, and through setting up the magnetic fiber net, the bactericidal effect of silver ion is better for its magnetic field that produces, and possess the magnetotherapy effect. The hydrophilicity of the web is improved by the plasma treatment, so that the antibacterial agent is more easily absorbed by the web. The hydrophilic properties of a material are determined by its surface energy and surface microstructure, which can be measured by the contact angle of a liquid with a solid surface. According to the invention, the hydrophilicity of the fiber web is improved by adopting a high-energy ion beam bombardment and low-energy ion beam deposition process, firstly, the high-energy ion beam is utilized to bombard a fiber web substrate material to generate a random micro-nano protruding structure, the protruding structure is thick in root due to high-low dislocation, and is more firmly combined with an antibacterial agent, the generation of the micro-nano protruding structure can increase the roughness of the surface of the material, improve the contact angle between the surface of the material and the antibacterial agent, increase the adhesive force between the antibacterial agent and the fiber web substrate, reduce the surface energy of the surface of the material, and further improve the affinity between the material and the antibacterial agent. The treatment of the fiber web by the electric field can lead the fiber monomers on the fiber web to stand up, which is more beneficial to the permeation and embedding of the antibacterial agent; the fiber net coated with the antibacterial agent is subjected to magnetic field treatment under the condition that the antibacterial agent is not completely solidified, the direction of magnetic force lines in a magnetic field can be parallel to the running direction of the fiber net and can also be vertical to the running direction of the fiber net, after the fiber net passes through the magnetic field, the nano magnetic particles applied to the fiber net generate orientation effect under the action of an external magnetic field, so that the orientation of the magnetic particles is more regular, the auxiliary material has a magnetic field effect in a certain direction due to the regularly oriented magnetic particles, the blood microcirculation of the auxiliary material application position can be improved, and the healing and the tissue regeneration of a wound are promoted.

Detailed Description

In order to clearly illustrate the technical features of the present solution, the present solution is explained below by way of specific embodiments.

Implementation mode one

further, the fiber raw materials in the step 1) comprise 50% of antibacterial fibers, 20% of superfine thermal fibers and 30% of antibacterial silver ion fibers.

Further, the process of the carding machine in the step 3) is set as follows: the cylinder speed is 1000r/min, the doffer speed is 500r/min, the working roll speed is 300r/min, and the swinging frequency of the screen forming swing is 25 hz.

Further, the lower layer of the oven of the low-temperature oven for pre-drying in the step 8) is 40 ℃, the middle layer is 60 ℃ and the upper layer is 80 ℃; the temperature of the first area of the dryer for drying in the step 10) is 120 ℃, the temperature of the second area is 140 ℃, and the temperature of the third area is 160 ℃.

Further, the step 6)

Further, the plasma processing technology in the step 5) is that the frequency of a high-voltage power supply is 500HzHz, the pulse width is 2 mus, the voltage amplitude is-40 kV, and the processing time is 40 min.

Further, the first electric field in the step 7) is a capacitor electric field; the first magnetic field in the step 9) is a magnetic field generated by an electromagnetic coil, and the direction of magnetic lines in the magnetic field can be parallel to the running direction of the fiber web.

Second embodiment

further, the fiber raw materials in the step 1) comprise 80% of antibacterial fibers, 40% of superfine thermal fibers and 40% of antibacterial silver ion fibers.

Further, the process of the carding machine in the step 3) is set as follows: the cylinder speed is 1200r/min, the doffer is 800r/min, the working roll is 500r/min, and the swinging frequency of the screen forming swing is 30 hz.

Further, the lower layer of the oven of the low-temperature oven for pre-drying in the step 8) is 60 ℃, the middle layer is 80 ℃ and the upper layer is 100 ℃; the temperature of the first area of the dryer for drying in the step 10) is 140 ℃, the temperature of the second area is 160 ℃, and the temperature of the third area is 180 ℃.

Further, the step 6)

Further, the plasma processing technology in the step 5) is that the frequency of a high-voltage power supply is 800Hz, the pulse width is 10 mus, the voltage amplitude is-60 kV, and the processing time is 60 min.

Through adding certain nanometer titanium dioxide powder in the antibacterial agent, can absorb ultraviolet light, a large amount of hydroxyl free radicals that the silver ion in the antibiotic silver ion master batch primary fiber of nanometer passes through the photocatalytic reaction under the irradiation of ultraviolet light produces, can assault the microbial cell simultaneously through active oxygen group and silver ion from this, destroy cell wall and intracellular enzyme gene, thereby bactericidal effect has been improved, and through setting up the magnetic fiber net, the bactericidal effect of silver ion is better for its magnetic field that produces, and possess the magnetotherapy effect.

The hydrophilicity of the web is improved by the plasma treatment, so that the antibacterial agent is more easily absorbed by the web. The hydrophilic properties of a material are determined by its surface energy and surface microstructure, which can be measured by the contact angle of a liquid with a solid surface. According to the invention, the hydrophilicity of the fiber web is improved by adopting a high-energy ion beam bombardment and low-energy ion beam deposition process, firstly, the high-energy ion beam is utilized to bombard a fiber web substrate material to generate a random micro-nano protruding structure, the protruding structure is thick in root due to high-low dislocation, and is more firmly combined with an antibacterial agent, the generation of the micro-nano protruding structure can increase the roughness of the surface of the material, improve the contact angle between the surface of the material and the antibacterial agent, increase the adhesive force between the antibacterial agent and the fiber web substrate, reduce the surface energy of the surface of the material, and further improve the affinity between the material and the antibacterial agent.

The treatment of the fiber web by the electric field can lead the fiber monomers on the fiber web to stand up, which is more beneficial to the permeation and embedding of the antibacterial agent; the fiber net coated with the antibacterial agent is subjected to magnetic field treatment under the condition that the antibacterial agent is not completely solidified, the direction of magnetic force lines in a magnetic field can be parallel to the running direction of the fiber net and can also be vertical to the running direction of the fiber net, after the fiber net passes through the magnetic field, the nano magnetic particles applied to the fiber net generate orientation effect under the action of an external magnetic field, so that the orientation of the magnetic particles is more regular, the auxiliary material has a magnetic field effect in a certain direction due to the regularly oriented magnetic particles, the blood microcirculation of the auxiliary material application position can be improved, and the healing and the tissue regeneration of a wound are promoted.

Claims

1. The preparation method of the antibacterial auxiliary material is characterized by comprising the following steps:

9): leading the pre-dried fiber web to pass through a first magnetic field treatment area under the guide of a second guide roller set, and carrying out orientation treatment on the nano magnetic particles applied to the fibers under the action of an external magnetic field;

the lower layer of the oven of the low-temperature oven for pre-drying in the step 8) is 40-60 ℃, the middle layer is 60-80 ℃ and the upper layer is 80-100 ℃; the temperature of the first area of the dryer for drying in the step 10) is 120-140 ℃, the temperature of the second area is 140-160 ℃, and the temperature of the third area is 160-180 ℃;

the antibacterial agent in the step 6) is formed by mixing 80% of pure acrylic polymer emulsion, 1% of nano titanium dioxide powder and a biological antibacterial agent.