CN109646378A - A kind of nti-freckle lotion of skin whitening, moisturizing and preparation method thereof - Google Patents
A kind of nti-freckle lotion of skin whitening, moisturizing and preparation method thereof Download PDFInfo
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- CN109646378A CN109646378A CN201910094321.5A CN201910094321A CN109646378A CN 109646378 A CN109646378 A CN 109646378A CN 201910094321 A CN201910094321 A CN 201910094321A CN 109646378 A CN109646378 A CN 109646378A
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- skin
- stabilizer
- emulsifier
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- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 230000037370 skin discoloration Effects 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- Cosmetics (AREA)
Abstract
The invention belongs to cosmetic field, the nti-freckle lotion and preparation method thereof of especially a kind of skin whitening, moisturizing.It is more preferable with the stability under sunlight, it absorbs good, can effectively solve to have dry skin the problems such as coarse, skin is dark yellow, loose, color spot, make the soft white bright, high resilience of skin and smooth feeling, and highly-safe, is applied to not easy to change after skin, property is stablized, high production efficiency.The technical solution adopted by the present invention is that by weight including following components: emollient, skin conditioning agent, stabilizer, emulsifier and solvent；Wherein, the emollient is 40~100 parts of glycerol, 40~120 parts of ethylhexyl palmitate, 30~80 parts of glutathione, 80~150 parts of isononyl isononanoate, 60~110 parts of 1,2- pentanediol, 30~85 parts of resveratrol, 4~15 parts of Butyrospermum parkii fruit rouge, 4~10 parts of furfuryl thiopropionate.High production efficiency of the present invention, the stability under sunlight is more preferable, is not easy to be especially suitable for high-grade cosmetics because of light and temperature discoloring after being applied to skin.
Description
Technical field
The invention belongs to cosmetic field, the nti-freckle lotion and preparation method thereof of especially a kind of skin whitening, moisturizing.
Background technique
Whitening product has the powerful market demand in the cosmetic field of Asia, because of the generally existing skin of yellow's colour of skin
Skin pigment deposition, the colour of skin it is obscure or it is dim it is yellow, lack the problems such as gloss and easy allergy.It is even more to influence that pigment deposition, which forms color spot,
Skin beauty and health are mainly in cheek, forehead position and the back of the hand, aggravate after solarization.Research shows that the colour of skin is obscure and color spot
It is since the fine circulation between histocyte is hindered by silt, cell dissolution is dead, and melanin, which increases, to be formed, and the epidermis of face is most
Thin, capillary is most abundant, also most easily forms pigmentation, pigmentation position is mainly in basal layer of epidermis, melanin granule
It increased significantly, also have more melanin in the melanophage of more serious person's skin corium, compared with normal, the number of chromatophore
Mesh, melanin is formed and the activity of melanin granule has different growths.
Because of the protective effect of skin surface, cosmetics are difficult to work to basal layer of epidermis and skin corium.It is most
Cosmetics prescription is added to a large amount of natural flowers and fruits plant extract component can only make although certain repairing effect can be obtained
For epidermis stroma cell, and it is less act on basal layer of epidermis and skin corium, the effect of deep layer reparation cannot be obtained.And contain
There is a large amount of natural plant composition, not only higher cost, and it is complex to interact between effective ingredients in plant, stability
It remains to be discussed.It especially when prescription had not only contained effective ingredients in plant but also contained compound, is easy to interfere with each other between component, drop
Inefficient fruit is easy discoloration, goes bad.Moreover, the performance of each component is different, leads to complex process in production process, need to use more
Kind of process equipment, such as emulsifying pot, cause that equipment investment is big, energy consumption is high, and production efficiency is low, is not easy to be mass produced.It is special
Be not, some plant extracts be flour, it is difficult to and containing there are many mixture of esters be uniformly mixed, even use
The equipment such as emulsifying pot carry out long-time homogeneous and are also difficult to reach ideal effect.Composition after homogeneous is undergone in transit
Prescription conglomeration, layering, precipitating etc. are easily generated after the impact such as vibrating, colliding, falling, leads to not normal use.Some combinations
Object does not have apparent conglomeration, layering, deposited phenomenon even, to be proposed after shaking up yet and use.
The plant extracts of powdery is difficult to and containing there are many mixtures of esters to be uniformly mixed, and component effect is not easy to send out
It waves, component interacts, and causes cosmetics itself to be easy discoloration, failure in the sun, does not have protection when using in the sun
Effect.Especially cosmetic application is done after skin at a temperature of major part component effect of sunlight, light-illuminating and skin
It disturbs, decompose, the effect that skin really obtains is less.And in skin whitening, moisturizing, superior cosmetics is with greater need in view of cosmetics sheet
The coloured effect of body, the color for interfering skin.
Therefore, it is necessary to provide a kind of nti-freckle lotion and preparation method thereof of skin whitening, moisturizing, not only there is preferable whitening
Moistening effect, also can reach deep layer reparation, dispelling stain, and anti-vibrating and impact is applied to not easy to change, production technology letter after skin
It is single.
Summary of the invention
In order to solve above-mentioned deficiency, the present invention provides a kind of nti-freckle lotion and preparation method thereof of skin whitening, moisturizing, under sunlight
Stability it is more preferable, absorb good, can effectively solve to have dry skin the problems such as coarse, skin is dark yellow, loose, color spot, make skin
Soft white bright, high resilience and smooth feeling, and it is highly-safe, it is applied to not easy to change, property stabilization after skin, anti-vibration punching
It hits, high production efficiency.
In order to realize that goal of the invention of the invention, the present invention adopt the following technical scheme that:
A kind of nti-freckle lotion of skin whitening, moisturizing, by weight include following components: emollient, skin conditioning agent, stabilizer,
Emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 40~100 parts of glycerol, ethylhexyl palmitate 40
~120 parts, 30~80 parts of glutathione, 80~150 parts of isononyl isononanoate, 60~110 parts of 1,2- pentanediol, resveratrol 30
~85 parts, 4~15 parts of Butyrospermum parkii fruit rouge；
Skin conditioning agent is by weight: 4~12 parts of Fructificatio Tricholomatis Matsutakis extract, 5~15 parts of Gotu Kola P.E, aloe extract 4
~10 parts, 4~12 parts of ginkgo biloba p.e, 4~10 parts of grape seed oil；
4~15 parts of stabilizer, 8~35 parts of emulsifier；
Solvent are as follows: 300~1000 parts of water.
Further, the emollient further include: 4~10 parts of furfuryl thiopropionate；
Further, the emulsifier is by weight: 3~15 parts of methyl sesquistearate, glycerol stearate
3~15 parts of ester；
Further, the stabilizer is by weight: 3~10 parts of sodium acetate, 3~12 parts of ethyl perfluorobutyl ether, first
3~10 parts of ester of base silane alcohol mannuronic acid.
A kind of preparation method of the nti-freckle lotion of above-mentioned skin whitening, moisturizing is:
(1) oily mutually material is heated to 75-90 DEG C, stirring fusing；It is described oil mutually material include glycerol, ethylhexyl palmitate,
Isononyl isononanoate, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 65-80 DEG C, stirring and dissolving；The water phase material includes Fructificatio Tricholomatis Matsutakis extract, centella extraction
Object, aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.7-0.2 atmospheric pressure of negative pressure
It mixes uniformly, is cooled to 35-50 DEG C, discharging；
(4) filling, packaging.
Glutathione can assist in keeping the function of normal immune system, and there is antioxidation and integration removing toxic substances to make
With to skin with anti-aging, whitening spot-removing effect.
Contain a variety of amino acid, polysaccharide, microelement, phenols, tannin, alkaloid and vitamin in Fructificatio Tricholomatis Matsutakis extract.Its
There is outstanding contribution in skin care industry, especially in terms of whitening.Modern research shows that matsutake extracting solution, which has, inhibits skin table
Complexion element biological chemical performance.Meanwhile blazei polysaccharide contained therein can promote the removing of body free radical, and it is anti-to increase body
Oxidability has significant protective effect to radiogenic immunologic mjury.
Gotu Kola P.E, CAS 84696-21-9, the triterpenes containing there are many, wherein including α-amyrin structure.It is main
Wanting ingredient is Asiaticoside, madecassoside, appearance brown color to white fine powder, mouthfeel slight bitter.It can be with compact epidermis
With corium coupling part, skin can be made to limber up, help to solve cutis laxa phenomenon, keep skin smooth flexible；Make skin
Achieve the effect that compact smooth.
Algisium C has excellent absorption, dispersibility, reduces sunlight to caused by skin
Discoloration and pigment aggregation promote the horn cell containing melanin to fall off, to effectively decompose, be metabolized melanin, inhibit melanin
It generates and realizes white-skinned face function；It soothes the skin surface layer, softened cuticula, increase local skin temperature, expand pore and sweat gland
Mouth is conducive to each component and passes through epidermis, and guidance component enters basal layer of epidermis and skin corium plays effect, raising absorption efficiency.
Furfuryl thiopropionate and ethylhexyl palmitate act synergistically, firstly, improving the photostability of composition, avoid group
Object discoloration, conglomeration, layering under sunlight irradiation is closed, cosmetics will not be caused to change colour because of being exposed under light after being applied to skin
Interfere skin color；Secondly induction horn cell metabolism normalization promotes the horn cell containing melanin to fall off；Promote indirectly
Break up into fibrocyte, while promoting the synthesis of collagen, skin corium is promoted to rebuild, stimulates cell neogenesis, mend comprehensively in time
To cytotrophy, cell membrane is reinforced, protects Skin Cell from free radical injury, effectively melanin is inhibited to generate, and decompose
The melanin of precipitating, decomposition subtract light color spot, and prevention and treatment skin generates allergy, spot under sunlight irradiation, under the stimulation such as wound, frostbite
And color spot.
Fructificatio Tricholomatis Matsutakis extract and Gotu Kola P.E are flour, it is difficult to and containing there are many mixing of the emollient of esters is equal
It is even, and only material mixes, and the effect of small molecule mixing is not achieved, and skin is difficult to absorb, it is more difficult to rise to deep skin
Effect.And after mixing, by long-time homogenization, its mixed effect is still not ideal enough, and mixture is not sufficiently stable, for a long time
Placement is easy to appear segregation phenomenon.It especially to undergo to fall during transportation and fall shock and vibration, high temperature, solarization, easily generate
Layering, precipitating, component agglomerate, in addition it is rotten.Ethyl perfluorobutyl ether is used to improve the mixing efficiency and effect of the application prescription,
Reduce homogenizing step and incorporation time.In this production technology, it is empty to generate bubble for ethyl perfluorobutyl ether in negative pressure whipping process
Chamber, but the bubble and uneven that ethyl perfluorobutyl ether is formed in negative pressure whipping process, cause mixed effect not good enough.First
Base silane alcohol mannuronic acid ester makes ethyl perfluorobutyl ether faster generate bubble under same pressure, the energy as long as less negative pressure
A large amount of to generate bubble cavity, bubble is more evenly.Sodium acetate restraining Algisium C makes ethyl perfluorobutyl ether
The speed for generating bubble under negative pressure, avoids generating a large amount of bubbles suddenly, keeps the bubble of ethyl perfluorobutyl ether smaller, closeer
Collection, more evenly, to improve the homogeneous mixing quality and process controllability of entire prescription.Cavity Blasting generate partial high pressure and
Impact keeps Algisium C and cosmetics each component conglomeration closer uniformly, realizes after skin surface is releived
Guidance component enters basal layer of epidermis in time and skin corium plays effect, better than the mixed effect of homogeneous.
In plant extracts bioactivity silicon mainly with the substances network such as tannic acid and and exist.Under sunlight irradiation, tannin
Acid is degradable, while silicon aquation forms amorphous SiO2 .nH2O, and polymerize and form silicic acid quasi polymer, finally loses activity.Beauty
A certain amount of stabilizer is added in the nti-freckle lotion of white moisturizing, and tannic acid can be effectively suppressed and degrade because illumination and storage time are long, press down
Elemental silicon processed is further formed the ingredients such as polysilicon acid because illumination and storage time are long, makes elemental silicon with the shape of organic trace element
Formula exists without decomposing, and obtained composition is made to remain to play preferable moisturizing whitening spot-removing function after illumination and long-time storage.
The utility model has the advantages that
The application stablizes, and the not easy to change, failure under sunlight irradiation avoids the skin under sunlight from generating color spot.Mixing
Effect is not easy to be separated by solid-liquid separation well, and storage time is more long, it is resistance to it is vibrated, collide, to fall ability strong.The application is rapid-action, reduces sun
Light to discoloration caused by skin and pigment aggregation, deep skin can be risen effect make the soft white bright, high resilience of skin and
Smooth feeling, and it is highly-safe, and property is stablized, high production efficiency.Stability under sunlight is more preferable, be applied to after skin be not easy because
For light and temperature discoloring, it is especially suitable for high-grade cosmetics.
Specific embodiment
Technical solution of the present invention is described in further detail combined with specific embodiments below, but the present invention is not limited to following
Embodiment.Unless otherwise indicated, various components used in the present invention are this field current material, can be purchased by commercial channel
It buys acquisition or is made by existing method.
Embodiment 1
A kind of nti-freckle lotion of skin whitening, moisturizing, by weight include following components: emollient, skin conditioning agent, stabilizer,
Emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 45 parts of glycerol, 113 parts of ethylhexyl palmitate, paddy
It is 37 parts of the sweet peptide of Guang, 138 parts of isononyl isononanoate, 74 parts of 1,2- pentanediol, 80 parts of resveratrol, 5 parts of Butyrospermum parkii fruit rouge, thio
8 parts of furfuryl propionate；
Skin conditioning agent is by weight: 5 parts of Fructificatio Tricholomatis Matsutakis extract, 13 parts of Gotu Kola P.E, 6 parts of aloe extract, ginkgo
10 parts of leaf extract, 5 parts of grape seed oil；
5 parts of stabilizer, 30 parts of emulsifier；
Solvent are as follows: 930 parts of water.
Further, the emulsifier is by weight: 5 parts of methyl sesquistearate, stearine 13
Part；
Further, the stabilizer is by weight: 8 parts of sodium acetate, 10 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol
9 parts of mannuronic acid ester.
A kind of preparation method of the nti-freckle lotion of above-mentioned skin whitening, moisturizing is:
(1) oily mutually material is heated to 87 DEG C, stirring fusing；Mutually material includes glycerol, ethylhexyl palmitate, different nonyl to the oil
The different nonyl ester of acid, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 78 DEG C, stirring and dissolving；The water phase material include Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E,
Aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.6 atmospheric pressure of negative pressure equal
It is even, 36 DEG C are cooled to, discharging；
(4) filling, packaging.
Embodiment 2
A kind of nti-freckle lotion of skin whitening, moisturizing, by weight include following components: emollient, skin conditioning agent, stabilizer,
Emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 90 parts of glycerol, 50 parts of ethylhexyl palmitate, paddy
72 parts of the sweet peptide of Guang, 90 parts of isononyl isononanoate, 105 parts of 1,2- pentanediol, 40 parts of resveratrol, 14 parts of Butyrospermum parkii fruit rouge, sulphur
For 5 parts of furfuryl propionate；
Skin conditioning agent is by weight: 10 parts of Fructificatio Tricholomatis Matsutakis extract, 6 parts of Gotu Kola P.E, 8 parts of aloe extract, ginkgo
5 parts of leaf extract, 10 parts of grape pip；
12 parts of stabilizer, 10 parts of emulsifier；
Solvent are as follows: 380 parts of water.
Further, the emulsifier is by weight: 12 parts of methyl sesquistearate, stearine 5
Part；
Further, the stabilizer is by weight: 5 parts of sodium acetate, 5 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol
5 parts of mannuronic acid ester.
A kind of preparation method of the nti-freckle lotion of above-mentioned skin whitening, moisturizing is:
(1) oily mutually material is heated to 80 DEG C, stirring fusing；Mutually material includes glycerol, ethylhexyl palmitate, different nonyl to the oil
The different nonyl ester of acid, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 70 DEG C, stirring and dissolving；The water phase material include Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E,
Aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.35 atmospheric pressure of negative pressure equal
It is even, 40 DEG C are cooled to, discharging；
(4) filling, packaging.
Embodiment 3
A kind of nti-freckle lotion of skin whitening, moisturizing, by weight include following components: emollient, skin conditioning agent, stabilizer,
Emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 70 parts of glycerol, 85 parts of ethylhexyl palmitate, paddy
It is 55 parts of the sweet peptide of Guang, 112 parts of isononyl isononanoate, 85 parts of 1,2- pentanediol, 57 parts of resveratrol, 9 parts of Butyrospermum parkii fruit rouge, thio
8 parts of furfuryl propionate；
Skin conditioning agent is by weight: 8 parts of Fructificatio Tricholomatis Matsutakis extract, 9 parts of Gotu Kola P.E, 7 parts of aloe extract, ginkgo leaf
8 parts of extract, 8 parts of grape seed oil；
10 parts of stabilizer, 20 parts of emulsifier；
Solvent are as follows: 700 parts of water.
Further, the emulsifier is by weight: 9 parts of methyl sesquistearate, stearine 10
Part；
Further, the stabilizer is by weight: 6 parts of sodium acetate, 7 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol
8 parts of mannuronic acid ester.
A kind of preparation method of the nti-freckle lotion of above-mentioned skin whitening, moisturizing is:
(1) oily mutually material is heated to 82 DEG C, stirring fusing；Mutually material includes glycerol, ethylhexyl palmitate, different nonyl to the oil
The different nonyl ester of acid, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 70 DEG C, stirring and dissolving；The water phase material include Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E,
Aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.5 atmospheric pressure of negative pressure equal
It is even, 45 DEG C are cooled to, discharging；
(4) filling, packaging.
Embodiment 4
A kind of nti-freckle lotion of skin whitening, moisturizing, by weight include following components: emollient, skin conditioning agent, stabilizer,
Emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 60 parts of glycerol, 60 parts of ethylhexyl palmitate, paddy
It is 40 parts of the sweet peptide of Guang, 90 parts of isononyl isononanoate, 65 parts of 1,2- pentanediol, 35 parts of resveratrol, 6 parts of Butyrospermum parkii fruit rouge, thio
5 parts of furfuryl propionate；
Skin conditioning agent is by weight: 11 parts of Fructificatio Tricholomatis Matsutakis extract, 12 parts of Gotu Kola P.E, 8 parts of aloe extract, ginkgo
10 parts of leaf extract, 7 parts of grape seed oil；
13 parts of stabilizer, 30 parts of emulsifier；
Solvent are as follows: 800 parts of water.
Further, the emulsifier is by weight: 11 parts of methyl sesquistearate, stearine 9
Part；
Further, the stabilizer is by weight: 4 parts of sodium acetate, 8 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol
10 parts of mannuronic acid ester.
A kind of preparation method of the nti-freckle lotion of above-mentioned skin whitening, moisturizing is:
(1) oily mutually material is heated to 85 DEG C, stirring fusing；Mutually material includes glycerol, ethylhexyl palmitate, different nonyl to the oil
The different nonyl ester of acid, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 70 DEG C, stirring and dissolving；The water phase material include Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E,
Aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.6 atmospheric pressure of negative pressure equal
It is even, 42 DEG C are cooled to, discharging；
(4) filling, packaging.
Comparative example 1: the difference of comparative example 1 and embodiment 3 is that, without containing furfuryl thiopropionate, remaining condition is homogeneous
Together.
Comparative example 2: the difference of comparative example 2 and embodiment 3 is that, without containing ethylhexyl palmitate, remaining condition is homogeneous
Together.
Comparative example 3: the difference of comparative example 3 and embodiment 3 is without containing Algisium C, remaining
Condition is all the same.
Comparative test 1: select healthy adult cavy as experimental animal, experimental animal weight range are as follows: cavy 350g~
450g.Experimental animal skin health is without breakage.Animal will adapt to the 3d time in experimental animal room before testing.Conventional feed is selected,
Drinking-water does not limit.Every group of cavy is 10, half male and half female.The coat at back is cut off, manufactures spot, laser with dry ice frostbite respectively
Irradiation manufacture spot smears ammonium hydroxide manufacture spot, ultraviolet light irradiation manufacture spot.Then the 3d time is raised in experimental animal room,
To the composition of spot application embodiment 1-4 and comparative example 1-3, spot extinction time, unit: day are recorded.
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Comparative example 1 | Comparative example 2 | Comparative example 3 | |
| Color dodge | 4.7 | 4.9 | 4.5 | 5.1 | 8.6 | 8.9 | 9.2 |
| Color spot disappears | 10.4 | 10.1 | 9.2 | 9.8 | 14.6* | 15.2* | 15.9* |
| Scar disappears | 15.1 | 14.8 | 13.6 | 14.6 | 22.7* | 23.2* | 24.6* |
Table 1
In table 1, * is not just subtracting light, disappearance after representing to certain day, therefore not disappear.
Comparative example 1,2 is compared pair with embodiment 1-4, illustrates that furfuryl thiopropionate and ethylhexyl palmitate act synergistically,
It is aided with Algisium C and improves assimilation effect, the horn cell containing melanin can be effectively facilitated and fallen off, point
The melanin of precipitating is solved, decomposition subtracts light color spot, prevents and treats skin spot and color spot.
Comparative example 3 is compared pair with test example 1-4, illustrates that Algisium C can make that effect is guided to reach
Basal layer of epidermis and skin corium play effect, improve assimilation effect.Color spot and scar, which fail to completely disappear explanation, does not have methyl silicon
Alkanol mannuronic acid ester to superficial skin releive and guiding function, furfuryl thiopropionate are cooperateed with ethylhexyl palmitate
Except spot effect cannot arrive at basal layer of epidermis and skin corium, therefore spot cannot be completely eliminated.
Comparative example 3 is compared with test example 1-4 to smell, and the smell of comparative example 3 is dense, fragrance weight, and test example 1-4 smell is clear
It is light, the pure and fresh easy people of fragrance.Illustrate that Algisium C inhibits the smell of furfuryl thiopropionate, make the easy people of smell,
Avoid pungent taste.
Check experiment 2, light color test
The composition that embodiment and reference examples provide is tested with ultraviolet ray ageing case, temperature 60 is selected in vibration
DEG C, illumination condenses the period: 8H illumination, 4H condensation, UV irradiation level 35W/M2.Vibration be in order to simulate the vibration in transportational process,
Collision, temperature 60 C and ultraviolet light irradiate to test the validity period of long-term preservation.Every kind of composition provides 10 test specimens, note
Record the test data of each group, unit: H.
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Comparative example 1 | Comparative example 2 | Comparative example 3 | |
| Discoloration | 229.2 | 211.5 | 267.2 | 271.6 | 124.5 | 110.8 | 263.4 |
| Conglomeration | / | / | / | / | 184.5 | 157.3 | / |
| Layering | / | / | / | / | 227.7 | 209.5 | / |
| Precipitating | / | / | / | / | 260.7 | 248.1 | / |
Table 2
/ it is unchanged when testing 360H.
Embodiment 1-4, reference examples 3 in table 2 are compared pair with reference examples 1-2, illustrate furfuryl thiopropionate and palmitinic acid second
The own ester synergistic effect of base, improves the photostability of composition, avoids composition from changing colour under sunlight irradiation, be applied to after skin not
It can be more suitable for preparing high-grade cosmetics because being exposed under light leads to cosmetics discoloration interference skin color；And not
Easy to knot groups, layering and precipitating, shelf-life are longer.
Embodiment 1-4, reference examples 3 and the conglomeration of reference examples 1-2, layering, precipitating project are compared pair, illustrate propane thioic acid
Chaff ester and ethylhexyl palmitate are shared in the application, and the stability that composition can be made to mix is more preferable, are met during transportation
To vibration, collide, fall etc. also not easy to knot groups, layering, precipitating.
Check experiment 3, tannic acid and the detection of silicon degradation rate
Comparative example 4: the difference of comparative example 4 and embodiment 4 is without containing stabilizer provided by the present application, remaining condition
It is all the same.
Embodiment 1-4 and comparative example 4 composition provided are tested with ultraviolet ray ageing case, temperature is selected in vibration
60 DEG C, illumination condenses the period: 8H illumination, 4H condensation, UV irradiation level 35W/M2.Vibration is to simulate the vibration in transportational process
Dynamic, collision, temperature 60 C and ultraviolet light irradiate to test the validity period of long-term preservation.Every kind of composition provides 10 tests
Sample records tannic acid and silicon degradation rate.
Table 3
Embodiment 1-4 in table 3 is compared with comparative example 4 pair it is found that stabilizer can be effectively suppressed tannic acid because of illumination and
Storage time is degraded long, is inhibited elemental silicon to be further formed the ingredients such as polysilicon acid because illumination and storage time are long, is made simple substance
Silicon in the form of organic trace element exist without decompose, make be made composition remained to after illumination and long-time storage play compared with
Good moisturizing whitening spot-removing function.
Check experiment 4: the mixed effect of homogeneous
Comparative example 5: the difference of comparative example 5 and embodiment 1 is that, without containing ethyl perfluorobutyl ether, remaining condition is homogeneous
Together.
Comparative example 6: the difference of comparative example 6 and embodiment 1 is without containing Algisium C, remaining
Condition is all the same.
Comparative example 7: the difference of comparative example 7 and embodiment 1 is that, without containing sodium acetate, remaining condition is all the same.
The condition of production of recording step (3) in process of production.
Embodiment 1 has uniformly fine and closely woven bubble generation, 1600 turns/min revolving speed stirring 5 minutes in 0.6 atmospheric pressure of negative pressure
It can be uniformly mixed, complete homogeneous.
Comparative example 5, in 0.6 atmospheric pressure of negative pressure, bubble-free is generated, and 1600 turns/min revolving speed stirs 60 minutes mixabilities
It is still undesirable.
Comparative example 6, in 0.6 atmospheric pressure of negative pressure, the bubble of generation is extremely uneven, and a large amount of bubbles that generate cause to overflow suddenly
Out, revolving speed is unable to reach stabilization, can not continue to produce.
Comparative example 7 could generate bubble, and bubble is few in 0.9 atmospheric pressure of negative pressure, and mixed effect is poor, and 1600 turns/min
It is still undesirable that revolving speed stirs 60 minutes mixabilities.
The above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair
Limitation of the invention, protection scope of the present invention should be defined by the scope defined by the claims..For the art
For those of ordinary skill, without departing from the spirit and scope of the present invention, several improvements and modifications can also be made, these change
It also should be regarded as protection scope of the present invention into retouching.
Claims (10)
1. a kind of nti-freckle lotion of skin whitening, moisturizing, it is characterised in that by weight include following components: emollient, skin condition
Agent, stabilizer, emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 40~100 parts of glycerol, ethylhexyl palmitate 40~120
Part, 30~80 parts of glutathione, 80~150 parts of isononyl isononanoate, 60~110 parts of 1,2- pentanediol, resveratrol 30~85
Part, 4~15 parts of Butyrospermum parkii fruit rouge, 4~10 parts of furfuryl thiopropionate；
Skin conditioning agent is by weight: 4~12 parts of Fructificatio Tricholomatis Matsutakis extract, 5~15 parts of Gotu Kola P.E, aloe extract 4~10
Part, 4~12 parts of ginkgo biloba p.e, 4~10 parts of grape seed oil；
4~15 parts of stabilizer, 8~35 parts of emulsifier；
Solvent are as follows: 300~1000 parts of water.
2. the nti-freckle lotion of a kind of skin whitening, moisturizing according to claim 1, it is characterized in that the emollient further include: sulphur
For 4~10 parts of furfuryl propionate.
3. a kind of nti-freckle lotion of skin whitening, moisturizing according to claim 1, it is characterized in that the emulsifier is by weight:
3~15 parts of methyl sesquistearate, 3~15 parts of stearine.
4. a kind of nti-freckle lotion of skin whitening, moisturizing according to claim 1, it is characterized in that the stabilizer is by weight:
3~10 parts of sodium acetate, 3~12 parts of ethyl perfluorobutyl ether, 3~10 parts of Algisium C.
5. according to claim 1, a kind of nti-freckle lotion of skin whitening, moisturizing described in 2,4, it is characterized in that by weight including following
Component: emollient, skin conditioning agent, stabilizer, emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 40~100 parts of glycerol, ethylhexyl palmitate 40~120
Part, 30~80 parts of glutathione, 80~150 parts of isononyl isononanoate, 60~110 parts of 1,2- pentanediol, resveratrol 30~85
Part, 4~15 parts of Butyrospermum parkii fruit rouge, 4~10 parts of furfuryl thiopropionate；
Skin conditioning agent is by weight: 4~12 parts of Fructificatio Tricholomatis Matsutakis extract, 5~15 parts of Gotu Kola P.E, aloe extract 4~10
Part, 4~12 parts of ginkgo biloba p.e, 4~10 parts of grape seed oil；
4~15 parts of stabilizer, 8~35 parts of emulsifier；
Solvent are as follows: 300~1000 parts of water；
The stabilizer is by weight: 3~10 parts of sodium acetate, 3~12 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol mannose
3~10 parts of aldehydic acid ester.
6. a kind of nti-freckle lotion of skin whitening, moisturizing described in -5 according to claim 1, it is characterized in that by weight by following components
Composition: emollient, skin conditioning agent, stabilizer, emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 40~100 parts of glycerol, ethylhexyl palmitate 40~120
Part, 30~80 parts of glutathione, 80~150 parts of isononyl isononanoate, 60~110 parts of 1,2- pentanediol, resveratrol 30~85
Part, 4~15 parts of Butyrospermum parkii fruit rouge, 4~10 parts of furfuryl thiopropionate；
Skin conditioning agent is by weight: 4~12 parts of Fructificatio Tricholomatis Matsutakis extract, 5~15 parts of Gotu Kola P.E, aloe extract 4~10
Part, 4~12 parts of ginkgo biloba p.e, 4~10 parts of grape seed oil；
4~15 parts of stabilizer, 8~35 parts of emulsifier；
Solvent are as follows: 300~1000 parts of water；
The emulsifier is by weight: 3~15 parts of methyl sesquistearate, 3~15 parts of stearine；
The stabilizer is by weight: 3~10 parts of sodium acetate, 3~12 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol mannose
3~10 parts of aldehydic acid ester.
7. a kind of preparation method of the nti-freckle lotion of skin whitening, moisturizing according to claim 4-6, it is characterized in that: negative pressure is stirred
It mixes.
8. a kind of preparation method of the nti-freckle lotion of skin whitening, moisturizing described in -6 according to claim 1, it is characterized in that:
(1) oily mutually material is heated to 75-90 DEG C, stirring fusing；Mutually material includes glycerol, ethylhexyl palmitate, different nonyl to the oil
The different nonyl ester of acid, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 65-80 DEG C, stirring and dissolving；The water phase material include Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E,
Aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.7-0.2 atmospheric pressure of negative pressure equal
It is even, it is cooled to 35-50 DEG C, discharging；
(4) filling, packaging.
9. a kind of nti-freckle lotion of skin whitening, moisturizing described in -8 according to claim 1, it is characterized in that by weight by following components
Composition: emollient, skin conditioning agent, stabilizer, emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 40~100 parts of glycerol, ethylhexyl palmitate 40~120
Part, 30~80 parts of glutathione, 80~150 parts of isononyl isononanoate, 60~110 parts of 1,2- pentanediol, resveratrol 30~85
Part, 4~15 parts of Butyrospermum parkii fruit rouge, 4~10 parts of furfuryl thiopropionate；
Skin conditioning agent is by weight: 4~12 parts of Fructificatio Tricholomatis Matsutakis extract, 5~15 parts of Gotu Kola P.E, aloe extract 4~10
Part, 4~12 parts of ginkgo biloba p.e, 4~10 parts of grape seed oil；
4~15 parts of stabilizer, 8~35 parts of emulsifier；
Solvent are as follows: 300~1000 parts of water；
The emulsifier is by weight: 3~15 parts of methyl sesquistearate, 3~15 parts of stearine；
The stabilizer is by weight: 3~10 parts of sodium acetate, 3~12 parts of ethyl perfluorobutyl ether, methyl-monosilane alcohol mannose
3~10 parts of aldehydic acid ester；
Preparation method, it is characterized in that:
(1) oily mutually material is heated to 75-90 DEG C, stirring fusing；Mutually material includes glycerol, ethylhexyl palmitate, different nonyl to the oil
The different nonyl ester of acid, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 65-80 DEG C, stirring and dissolving；The water phase material include Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E,
Aloe extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred under 0.7-0.2 atmospheric pressure of negative pressure equal
It is even, it is cooled to 35-50 DEG C, discharging；
(4) filling, packaging.
10. a kind of nti-freckle lotion of skin whitening, moisturizing described in -8 according to claim 1, it is characterised in that packet is by following by weight
Group is grouped as: emollient, skin conditioning agent, stabilizer, emulsifier and solvent；
Wherein, the emollient is composed of the following components by weight: 45 parts of glycerol, 113 parts of ethylhexyl palmitate, gluathione
37 parts of peptide, 138 parts of isononyl isononanoate, 74 parts of 1,2- pentanediol, 80 parts of resveratrol, 5 parts of Butyrospermum parkii fruit rouge, propane thioic acid
8 parts of chaff ester；
Skin conditioning agent is by weight: 5 parts of Fructificatio Tricholomatis Matsutakis extract, 13 parts of Gotu Kola P.E, 6 parts of aloe extract, ginkgo leaf mention
Take 10 parts of object, 5 parts of grape seed oil；
5 parts of stabilizer, 30 parts of emulsifier；
Solvent are as follows: 930 parts of water；
The emulsifier is by weight: 5 parts of methyl sesquistearate, 13 parts of stearine；
The stabilizer is by weight: 8 parts of sodium acetate, 10 parts of ethyl perfluorobutyl ether, Algisium C 9
Part；
Preparation method is:
(1) oily mutually material is heated to 87 DEG C, stirring fusing；Mutually material is different including glycerol, ethylhexyl palmitate, isononanoic acid for the oil
Nonyl ester, 1,2- pentanediol, resveratrol, Butyrospermum parkii fruit rouge, furfuryl thiopropionate, grape seed oil；
(2) water phase material is heated to 78 DEG C, stirring and dissolving；The water phase material includes Fructificatio Tricholomatis Matsutakis extract, Gotu Kola P.E, aloe
Extract, ginkgo biloba p.e, glutathione, water；
(3) under stirring, by stabilizer, emulsifier, oil, mutually material is added in water phase, is stirred evenly under 0.6 atmospheric pressure of negative pressure, is dropped
Temperature is to 36 DEG C, discharging；
(4) filling, packaging.
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| CN116236428A (en) * | 2023-03-02 | 2023-06-09 | 佐登妮丝（广州）美容化妆品有限公司 | Whitening and moisturizing composition, emulsion and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1806855A (en) * | 2005-11-30 | 2006-07-26 | 合肥恒星医疗用品有限公司 | Wet wound dressing containing plant effective ingredient |
| CN107913204A (en) * | 2016-10-07 | 2018-04-17 | 申扬阳 | Ginkgo leaf facial treatment milk |
| CN108852945A (en) * | 2018-09-14 | 2018-11-23 | 广州艾蓓生物科技有限公司 | A kind of amino acid cleansing cream from foaming |
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2019
- 2019-01-30 CN CN201910094321.5A patent/CN109646378B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1806855A (en) * | 2005-11-30 | 2006-07-26 | 合肥恒星医疗用品有限公司 | Wet wound dressing containing plant effective ingredient |
| CN107913204A (en) * | 2016-10-07 | 2018-04-17 | 申扬阳 | Ginkgo leaf facial treatment milk |
| CN108852945A (en) * | 2018-09-14 | 2018-11-23 | 广州艾蓓生物科技有限公司 | A kind of amino acid cleansing cream from foaming |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116236428A (en) * | 2023-03-02 | 2023-06-09 | 佐登妮丝（广州）美容化妆品有限公司 | Whitening and moisturizing composition, emulsion and preparation method thereof |
| CN116236428B (en) * | 2023-03-02 | 2024-01-23 | 佐登妮丝（广州）美容化妆品有限公司 | Whitening and moisturizing composition, emulsion and preparation method thereof |
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