CN109645242A - A kind of piglet pearl shape blood enriching capsule and preparation method thereof - Google Patents

A kind of piglet pearl shape blood enriching capsule and preparation method thereof Download PDF

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Publication number
CN109645242A
CN109645242A CN201910024348.7A CN201910024348A CN109645242A CN 109645242 A CN109645242 A CN 109645242A CN 201910024348 A CN201910024348 A CN 201910024348A CN 109645242 A CN109645242 A CN 109645242A
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parts
piglet
pearl shape
capsule
raw material
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刘平祥
曾娟娟
陆应诚
刘金萍
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Guangdong Sanhang Biotechnology Co Ltd
Guangzhou Suntheme Biotechnology Co Ltd
Guangdong Driving Force Biological Polytron Technologies Inc
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Guangdong Sanhang Biotechnology Co Ltd
Guangzhou Suntheme Biotechnology Co Ltd
Guangdong Driving Force Biological Polytron Technologies Inc
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/30Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/60Feeding-stuffs specially adapted for particular animals for weanlings

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
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  • Food Science & Technology (AREA)
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  • Inorganic Chemistry (AREA)
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  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of piglet pearl shape blood enriching capsule, the piglet pearl shape capsule particle body that pearl shape blood enriching capsule is that diameter is 2-6mm, the capsule particle body includes the liquid medicine core positioned at external gelatinous layer and inside;The gelatinous layer is prepared by the raw material of following mass parts: 45-55 parts of water, 3-9 parts of sodium alginate, 3-9 parts of konjaku flour, the liquid medicine core are prepared by the raw material of following mass parts: 4-6 parts of the factor of enriching blood, 4-6 parts of complex enzyme formulation, 4-6 parts of compound micro-ecological preparation, nutrient solution and 35-45 parts of antistaling and antiseptic agent.Pearl shape blood enriching capsule palatability of the present invention is good, and animal is fond of, is easy to digest, easy absorption, and can adjust enteron aisle, promotes intestinal health development, improves the hematopoietic potential of piglet and the immunity of piglet.

Description

A kind of piglet pearl shape blood enriching capsule and preparation method thereof
Technical field
The invention belongs to field of feed, and in particular to a kind of piglet pearl shape blood enriching capsule and preparation method thereof.
Background technique
In order to improve sow productivity, column home utilization rate, Infection in Piglets infectious disease and parasitic disease are reduced, is broken by early stage Weaning Age is shortened to 21-28 age in days even earlier to shorten the nursing period of sow, but also leads to son at the same time by milk technology Pig produces stress.Suckling pig before wean, nutrition are completely or partially provided by breast milk, rouge rich in pig breast milk Fat and casein easy to digest;Its carbohydrate is the not starch-containing and fiber based on lactose.And after weaning, main energy The butterfat in amount source is substituted by cereal starch, and the casein that can be digested absorption completely becomes the lower plant of digestibility Albumen, and there are also the fibers that piglet can hardly digest in feed.When weaned piglet, due to stress factors such as environment, nutrition Influence, cause piglet to occur weightless, blood glucose, insulin and level of growth hormone, hepatic glycogen, gastric content weight reduce, stomach PH value, hydrocortisone free fatty acid levels increase, and often show as poor appetite, the disorders of digestion, diarrhea, growthing lag, Efficiency of feed utilization is low etc., that is, so-called early weaning piglet syndrome.
There are problems and deficiency for religion slot particulate material on the market now: product formula is not scientific, and nutrition is neither comprehensive Again unbalanced, extruding curing is improper.Extruding curing is insufficient, and particle is too hard, sucking pig bradymassesis, laborious, can be because of gum fatigue, pain Refuse to continue to search for food quickly bitterly, and because containing anti-nutritional factors in feed, sucking pig eats rear easy diarrhea;If full extruding, complete Curing then not only results in part nutritive loss in feed, and is easily broken into powder because particle is too soft, loses particulate material Benefit, this will obviously seriously affect the culture efficiency on pig farm.For above situation, in order to guarantee that piglet is successfully broken in early days Milk can mitigate again overcome therefore and caused by piglet strongly stress, reduce and from pig cream be converted to wound caused by solid feed, Patent application CN104855698A discloses a kind of anti-diarrhea liquid feed of capsule coating sucking pig.Under the capsule coating sucking pig is anti- Dysentery liquid feed is the ball-type capsule granule that diameter is 2~10mm, which includes positioned at external gelatinous layer and packet Liquid medicine core in the inner is wrapped up in, by weight percentage, the component of those granules includes: colloid 5~10%, Chinese medicine liquid 1 ~3%, remaining is nutrient solution and antistaling and antiseptic agent, wherein with weight ratio meter, the medicinal material component of the Chinese medicine liquid is constituted are as follows: yellow Stilbene: Chinese yam: honeysuckle: hawthorn: dark plum: Radix Glycyrrhizae=25~35:10~25:10~25:20~35:15~25:15~25.However The ingredient main function of above-mentioned capsule coating liquid feed be the anti-diarrhea of sucking pig, there is no for wean sucking pig anaemia problem and Immunity degradation problem is studied.
Summary of the invention
The object of the present invention is to provide a kind of piglet pearl shape blood enriching capsules.Animal is fond of, is easy to digest, easy absorption, Enteron aisle is adjusted, intestinal health can be promoted to develop, improve the hematopoietic potential of piglet and the immunity of piglet.
In order to achieve the above objectives, the present invention adopts the following technical solutions:
A kind of piglet pearl shape blood enriching capsule, the piglet is with the pearl that pearl shape blood enriching capsule is that diameter is 2-6mm Shape capsule particle body, the capsule particle body include the liquid medicine core positioned at external gelatinous layer and inside;The gelatinous layer Be prepared by the raw material of following mass parts: 45-55 parts of water, 3-9 parts of sodium alginate, 3-9 parts of konjaku flour, the liquid medicine core by The raw material of following mass parts is prepared: 4-6 parts of the factor of enriching blood, 4-6 parts of complex enzyme formulation, 4-6 parts of compound micro-ecological preparation, battalion Nutrient solution and 35-45 parts of antistaling and antiseptic agent;
The complex enzyme formulation is made of the raw material of following mass parts: 2-5 parts of cellulase, 2-5 parts of protease, amylase 2-5 parts, 2-5 parts of 1,4 beta-glucanase;The compound micro-ecological preparation includes the raw material of following mass parts: 3-6 parts of Bifidobacterium, thermophilic 3-6 parts of Lactobacillus lactis.
The present invention uses capsule coating liquid feed processing technology, uses the high-quality of few antigen and anti-nutritional factors original Material, is aided with the functional additives such as the factor of enriching blood, enzyme preparation, probiotics, produces a kind of hematopoietic function for enhancing piglet, Alleviate piglet iron-deficiency anemia, promote gastrointestinal health development, the piglet coating liquid feed for strengthening piglet autoimmunity is precious Pearl blood enriching capsule.
Preferably, the nutrient solution and antistaling and antiseptic agent are made of the raw material of following mass parts: 10-15 parts of whole milk, 3-9 parts of oligosaccharide, 3-9 parts of degreasing yellow meal worm powder, 1-3 parts of whey powder, 2-6 parts of plasma protein powder, 3-6 parts of lecithin, seawood meal 3-7 parts, 0.2-0.6 parts of calcium citrate, 0.2-0.6 parts of sodium alginate, 0.2-0.6 parts of saccharin, 0.06-0.12 parts of sorbic acid, water 50-60 parts.
It is further preferred that the nutrient solution and antistaling and antiseptic agent are made of the raw material of following mass parts: whole milk 12.5 part, 6 parts of oligosaccharide, 6 parts of degreasing yellow meal worm powder, 2 parts of whey powder, 4 parts of plasma protein powder, 4.5 parts of lecithin, seawood meal 5 Part, 0.4 part of calcium citrate, 0.4 part of sodium alginate, 0.4 part of saccharin, 0.09 part of sorbic acid, 55 parts of water.
Preferably, the factor of enriching blood is made of the raw material of following mass parts: 10-16 parts of PORPHYRIN IRON, vitamin e1 0-16 Part, vitamin B1210-16 parts, 20-30 parts of spinach extract.
It is further preferred that the factor of enriching blood is made of the raw material of following mass parts: 13 parts of PORPHYRIN IRON, vitamin e1 3 Part, vitamin B1213 parts, 25 parts of spinach extract.
Preferably, the complex enzyme formulation is made of the raw material of following mass parts: 3.5 parts of cellulase, protease 3 .5 Part, 3.5 parts of amylase, 3.5 parts of 1,4 beta-glucanase.
Preferably, the compound micro-ecological preparation includes the raw material of following mass parts: 4.5 parts of Bifidobacterium, acidophilus cream bar 4.5 parts of bacterium.
The preparation method of the spinach extract: using fresh spinach as raw material, tinning after cleaning, 6 cubes of tanks can fill 2000 Kilogram, 10 times of amount water boilings are extracted three times, combined extract, concentration and evaporation water, until specific gravity d=1.10 medicinal extract, spray drying, obtain Spinach extract powder, pulverizer crush, and vibrating screen sieves with 100 mesh sieve, and mix, and pack to get finished product.
The formula components effect of piglet of the present invention pearl shape blood enriching capsule is as follows.
Sodium alginate: a kind of natural polysaccharide, stability, dissolubility, viscosity and safety needed for there is pharmaceutical preparation auxiliary material Property, as gelling agent.
Konjaku flour: colloid is formed with after the molten water of sodium alginate, as colloid liquid.
PORPHYRIN IRON: at present medical field generally acknowledge to the most fast most lasting substance of hypoferric anemia effect, can be directly by human body Small intestinal absorption, the directly synthesis of participation erythrocyte.Simultaneously as iron atom is wrapped in Porphyrin Molecule, therefore when taking not It can stimulating gastrointestinal mucous membrane.
Vitamin E: liposoluble vitamin, hydrolysate are tocopherol, are one of most important antioxidant, tocopherol Sex hormone can be promoted to secrete, increase man's sperm motility and quantity;Increase woman's female hormone concentration, improves fertility energy Power, prevention of miscarriage.
Vitamin B12: cell division increment, DNA synthesis, the synthesis of protein are participated in, promotes the growth and development of body, mentions The utilization rate of high forage protein participates in manufacture erythrocyte, promotes the development and maturation of red blood cell, make at body hematopoietic function In normal condition, pernicious anaemia is prevented.
Spinach extract: cool in nature, acrid-sweet flavor tonifies the blood and arrest bleeding, relieving the five internal organs, promoting blood circulation, ease constipation of quenching the thirst, enriching yin calming the liver, helps and disappear Change.Contain a large amount of bata-carotene and iron and vitamin B6, folic acid, vitamin E, iron and potassium splendid source.Wherein, rich Rich iron has improvement result to hypoferric anemia;B family vitamin content abundant can prevent angular stomatitis, yctalopia etc. from tieing up The generation of raw element deficiency disease;Containing a large amount of antioxidant such as vitamin E etc., there is anti-aging, promote cel l proliferation.
Complex enzyme formulation: cellulase, protease, amylase, 1,4 beta-glucanase complex enzyme formulation can supplement endogenous enzyme Secretion that is insufficient and stimulating endogenous enzymes;Decomposing soluble non-starch polysaccharide improves the utilization rate of nutriment;It is strong to improve animal Health improves metaboilic level.
Bifidobacterium and lactobacillus acidophilus: Bifidobacterium is the main probiotics in a kind of large intestine, is had to human health Biological barrier, antitumor action, immunological enhancement, improves a variety of important lifes such as gastrointestinal function, anti-aging at trophism Manage function;Lactobacillus acidophilus not only under one's belt, the main probiotics in it or human small intestine;Both this mutually collaboration promotes, By safeguarding the microecological balance of entire gastrointestinal tract, play the role of promoting animal health.
Whole milk: protein rich in.
Oligosaccharide: as bifidus factor, it cannot be utilized by alimentary canal and pathogen, be only capable of being utilized by probiotics, make prebiotic Bacterium mass propagation enhances the competitive advantage of probiotics as the proliferation factor of probiotics.
Degreasing yellow meal worm powder: rich in protein, amino acid classes are complete and easy to digest and absorb, and can accelerate piglet Growth and development improves the anti pathologic immunity ability of piglet, reduces artificial breast deployment cost, increases economic efficiency.
Whey powder: its main component has lactose, lactalbumin, minerals etc., and nutritive value is high.A large amount of cream can be provided Sugar, fermentation can produce a large amount of lactic acid in piglet digestive, reduce alimentary canal pH value, help the digestion of cream, inhibit to cause a disease thin The growth of bacterium;The high quality lactalbumin contained have in piggy body high digestibility, good amino acid kenel, nonreactive nutrition because The advantage of son;Containing albumin and globulin (haemocyanin), equally there is positive influence, especially immune globulin on enteron aisle It is white, there is protecting effect to enteron aisle, Escherichia coli can be fought.The lactoperoxidase and lactoferrin contained in whey powder, tool There is sterilization, antibacterial.
Plasma protein powder: it is the high-quality protein source in early-weaned piglets daily ration, can be used as skimmed milk power and dry whey Substitute, palatability is higher than skimmed milk power.
Lecithin: promoting brain development, and the effect that protection liver, emulsification cut grease has certain hydrophily, there is increasing Heal the function of red pigment.
Seawood meal: algal polysaccharides, mannitol, amino acid, protein, vitamin and potassium, iron, calcium, phosphorus, iodine, selenium, cobalt are rich in Equal microelements, can not only supplement various microelements, moreover it is possible to improve pigling immunity.Add seawood meal in right amount in formula It can promote piglet development.
Calcium citrate: containing calcium abundant, provides the calcareous of abundance for the growth and development of piglet.
The present invention also provides the piglet preparation methods of pearl shape blood enriching capsule, include the following steps:
S1: the preparation of colloid liquid: water is put into heating tank, and sodium alginate, konjaku flour is added after being heated to boiling, is used in combination Glass bar continues stirring until boiling, after 8-10 minutes stop heating, by colloid liquid be put into cooling system be cooled to 65-75 DEG C it is standby With;
S2: PORPHYRIN IRON, vitamin E, vitamin B are chosen12, spinach extract, be sufficiently mixed uniformly after it is spare;
S3: choosing cellulase, protease, amylase, 1,4 beta-glucanase, spare after being sufficiently mixed uniformly;
S4: selecting probiotics Bifidobacterium, lactobacillus acidophilus, spare after being sufficiently mixed uniformly;
S5: whole milk, oligosaccharide, degreasing yellow meal worm powder, whey powder, plasma protein powder, lecithin are got all the in nutrient solution preparation ready It is standby to all substances whole dissolution to be put into stirring in container for rouge, seawood meal, calcium citrate, sodium alginate, saccharin, sorbic acid, water With;
S6: the nutrient solution of mixture obtained by step S2, S3 and step S5 is poured into blending tank, is continued by mixed liquor allotment It is stirred until homogeneous, the substance and impurity not being completely dissolved is filtered out with 60-80 mesh filter screen, by the mixed of obtained solution and step S4 Object is closed to mix well to obtain mixed liquor;
S7: the step S6 mixed liquor formed is delivered in the container of automation titration device by coating, and by step S1 system Standby colloid liquid is delivered in the cyclone vessel below titration device, starts and run titration system, and machine upper container mixes It closes liquid to instill below machine in cyclone vessel through titration kit, 8-12 minutes under eddy flow state, colloid liquid is just in titration at pearl The outside of the mixing titration drop of shape forms one layer of coating to get pearl shape capsule particle has been arrived.
Preferably, it also needs to be cleaned after coating, the satisfactory precious Beads of membrane wrapping thickness is transferred to cleaning system System rolls flushing 3-6 times using ladder type conveyer belt pure water is rolled, to obtain the pearl shape capsule of surface smooth form rule Particle.It is further preferred that also needing to sterilize after cleaning, the pearl shape capsule particle after cleaning is put into sterilization kettle, in 72- It is cooled to room temperature after being sterilized 20-25 minutes at a temperature of 76 DEG C.
Beneficial effects of the present invention:
1, the present invention uses capsule coating liquid feed processing technology, produces the treasure that a kind of surface is wet and slippery, shape is mellow and full Pearl capsule coating liquid feed, has the characteristics that wet soft, smooth, tender and crisp, fragrant and sweet, and palatability is splendid, is very suitable to just wean Piglet it is edible.It is in good taste, nutrition is comprehensive, easy to digest, guarantee piglet successfully wean and can mitigate wean caused by piglet Strongly stress, reduce and from pig cream be converted to solid feed bring wound;Can be relieved current creep feed because product formula is not scientific, Extruding curing it is improper it is equal caused by piglet development be obstructed, feed intake decline, the weaning syndromes such as diarrhea.
2, compound micro-ecological preparation of the invention and complex enzyme formulation combine the physilogical characteristics of weanling pig, weanling pig Digestive organs still incomplete development, lactobacillus acidophilus and Bifidobacterium intergrowth relation can effectively adjust enteron aisle, promote intestinal health Development;Enzyme preparation can supplement the secretion of endogenous enzyme deficiency, stimulation endogenous enzymes, improve the utilization rate of nutriment, reduce diarrhea; Oligosaccharide promotes probiotics mass propagation as bifidus factor, and as the proliferation factor of probiotics, the competition for enhancing probiotics is excellent Gesture.
3, the present invention provides PORPHYRIN IRONs, VB12, the material base for element of enriching blood is provided for piglet, enriches element of enriching blood Type, and the hematopoietic potential of body can be improved, improves the immunity of piglet;Spinach extract promotes enteron aisle to nutriment, The especially digestion and absorption of iron significantly improves piglet hematopoietic potential, alleviates hypoferric anemia, piglet yellow-white dysentery, depauperation etc. Iron deficiency symptoms are reduced to the harm for using chemical synthetic drug and antibiotic minimum.
4, product of the present invention carries out capsule coating into pearl shape, nutriment general equilibrium therein through special process technology And be in liquid condition, medicaments uniformity distribution and efficient absorption can be made.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this Invention be further described, but the present invention claims protection scope be not limited to embodiment.
Embodiment 1:
The preparation of piglet pearl shape blood enriching capsule
S1: the preparation of colloid liquid: after getting all each component of colloid ready, water 45Kg is put into heating tank, is heated to boiling After rising, sodium alginate 3Kg, konjaku flour 3Kg is added, and continue stirring until boiling with glass bar, stops heating after 8 minutes, by glue Matter liquid be put into cooling system be cooled to 65-75 DEG C it is spare.
S2: quality raw materials, PORPHYRIN IRON 1Kg, vitamin e1 Kg, vitamin B are chosen121Kg, spinach extract 2Kg, it is sufficiently mixed It is spare after closing uniformly.
S3: preferred enzyme preparation, cellulase 2Kg, protease 2Kg, amylase 2 Kg, 1,4 beta-glucanase 2Kg are sufficiently mixed It is spare after uniformly.
S4: preferred probiotics, Bifidobacterium 3Kg, lactobacillus acidophilus 3Kg, it is spare after being sufficiently mixed uniformly.
S5: whole milk 10Kg, oligosaccharide 3Kg, degreasing yellow meal worm powder 3Kg, whey powder 1Kg, blood are got all the in nutrient solution preparation ready Slurry protein powder 2Kg, lecithin 3Kg, seawood meal 3Kg, calcium citrate 0.2Kg, sodium alginate 0.2Kg, saccharin 0.2Kg, sorbic acid It is spare to all substances whole dissolution to be put into stirring in container by 0.06Kg, water 50Kg.
S6: mixed liquor allotment takes the nutrient solution 35Kg of mixture 4Kg and step S5 obtained by mixture 4Kg, S3 of step S2 It pours into blending tank, continues stirring until and uniformly filter out the substance and impurity not being completely dissolved with 60 mesh filter screens, it is molten by what is obtained The mixture 4Kg of liquid and step S4 mix well to obtain mixed liquor.
S7: the step S6 mixed liquor formed is delivered in the container of automation titration device by coating, and by step S1 system Standby colloid liquid is delivered in the cyclone vessel below titration device, starts and run titration system, and machine upper container mixes It closes liquid to instill below machine in cyclone vessel through titration kit, 8-12 minutes under eddy flow state, colloid liquid is just in titration at pearl The outside of the mixing titration drop of shape forms one layer of coating to get pearl shape capsule particle has been arrived.
It is cleaned after coating, the satisfactory precious Beads of membrane wrapping thickness is transferred to cleaning system, utilize rolling Ladder type conveyer belt is rolled with pure water and is rinsed 3-6 times, to obtain the more regular pearl shape capsule particle of surface more smooth form.Clearly It also needs to sterilize after washing, the pearl shape capsule particle after cleaning is put into sterilization kettle, sterilizes 20-25 at a temperature of 72-76 DEG C Minute after be cooled to room temperature to get.
Embodiment 2:
The preparation of piglet pearl shape blood enriching capsule
S1: the preparation of colloid liquid: after getting all each component of colloid ready, water 50Kg is put into heating tank, is heated to boiling After rising, sodium alginate 6Kg, konjaku flour 6Kg is added, and continue stirring until boiling with glass bar, stops heating after 9 minutes, by glue Matter liquid be put into cooling system be cooled to 65-75 DEG C it is spare.
S2: quality raw materials, PORPHYRIN IRON 13Kg, vitamin e1 3Kg, vitamin B are chosen1213Kg, spinach extract 25Kg, fill Divide spare after mixing.
S3: preferred enzyme preparation, cellulase 3.5Kg, protease 3 .5Kg, amylase 3.5Kg, 1,4 beta-glucanase 3.5Kg, It is spare after being sufficiently mixed uniformly.
S4: preferred probiotics, Bifidobacterium 4.5Kg, lactobacillus acidophilus 4.5Kg, it is spare after being sufficiently mixed uniformly.
S5: nutrient solution preparation, get all the ready whole milk 12.5Kg, oligosaccharide 6Kg, degreasing yellow meal worm powder 6Kg, whey powder 2Kg, Plasma protein powder 4Kg, lecithin 4.5Kg, seawood meal 5Kg, calcium citrate 0.4Kg, sodium alginate 0.4Kg, saccharin 0.4Kg, mountain It is spare to all substances whole dissolution to be put into stirring in container by pears acid 0.09Kg, water 55Kg.
S6: mixed liquor allotment takes the nutrient solution 45Kg of mixture 6Kg and step S5 obtained by mixture 6Kg, S3 of step S2 It pours into blending tank, continues stirring until and uniformly filter out the substance and impurity not being completely dissolved with 70 mesh filter screens, it is molten by what is obtained The mixture 6Kg of liquid and step S4 mix well to obtain mixed liquor.
S7: the step S6 mixed liquor formed is delivered in the container of automation titration device by coating, and by step S1 system Standby colloid liquid is delivered in the cyclone vessel below titration device, starts and run titration system, and machine upper container mixes It closes liquid to instill below machine in cyclone vessel through titration kit, 8-12 minutes under eddy flow state, colloid liquid is just in titration at pearl The outside of the mixing titration drop of shape forms one layer of coating to get pearl shape capsule particle has been arrived.
It is cleaned after coating, the satisfactory precious Beads of membrane wrapping thickness is transferred to cleaning system, utilize rolling Ladder type conveyer belt is rolled with pure water and is rinsed 3-6 times, to obtain the more regular pearl shape capsule particle of surface more smooth form.Clearly It also needs to sterilize after washing, the pearl shape capsule particle after cleaning is put into sterilization kettle, sterilizes 20-25 at a temperature of 72-76 DEG C Minute after be cooled to room temperature to get.
Embodiment 3:
The preparation of piglet pearl shape blood enriching capsule
S1: the preparation of colloid liquid: after getting all each component of colloid ready, water 55Kg is put into heating tank, is heated to boiling After rising, sodium alginate 9Kg, konjaku flour 9Kg is added, and continue stirring until boiling with glass bar, stops heating after ten minutes, by glue Matter liquid be put into cooling system be cooled to 65-75 DEG C it is spare.
S2: quality raw materials, PORPHYRIN IRON 16Kg, vitamin e1 6Kg, vitamin B are chosen1216Kg, spinach extract 30Kg, fill Divide spare after mixing.
S3: preferred enzyme preparation, cellulase 5Kg, protease 5Kg, amylase 5Kg, 1,4 beta-glucanase 5Kg are sufficiently mixed It is spare after uniformly.
S4: preferred probiotics, Bifidobacterium 6Kg, lactobacillus acidophilus 6Kg, it is spare after being sufficiently mixed uniformly.
S5: whole milk 15Kg, oligosaccharide 9Kg, degreasing yellow meal worm powder 9Kg, whey powder 3Kg, blood are got all the in nutrient solution preparation ready Slurry protein powder 6Kg, lecithin 6Kg, seawood meal 7Kg, calcium citrate 0.6Kg, sodium alginate 0.6Kg, saccharin 0.6Kg, sorbic acid It is spare to all substances whole dissolution to be put into stirring in container by 0.12Kg, water 60Kg.
S6: mixed liquor allotment takes the nutrient solution 40Kg of mixture 5Kg and step S5 obtained by mixture 5Kg, S3 of step S2 It pours into blending tank, continues stirring until and uniformly filter out the substance and impurity not being completely dissolved with 80 mesh filter screens, it is molten by what is obtained The mixture 5Kg of liquid and step S4 mix well to obtain mixed liquor.
S7: the step S6 mixed liquor formed is delivered in the container of automation titration device by coating, and by step S1 system Standby colloid liquid is delivered in the cyclone vessel below titration device, starts and run titration system, and machine upper container mixes It closes liquid to instill below machine in cyclone vessel through titration kit, 8-12 minutes under eddy flow state, colloid liquid is just in titration at pearl The outside of the mixing titration drop of shape forms one layer of coating to get pearl shape capsule particle has been arrived.
It is cleaned after coating, the satisfactory precious Beads of membrane wrapping thickness is transferred to cleaning system, utilize rolling Ladder type conveyer belt is rolled with pure water and is rinsed 3-6 times, to obtain the more regular pearl shape capsule particle of surface more smooth form.Clearly It also needs to sterilize after washing, the pearl shape capsule particle after cleaning is put into sterilization kettle, sterilizes 20-25 at a temperature of 72-76 DEG C Minute after be cooled to room temperature to get.
Embodiment 4:
The preparation of piglet pearl shape blood enriching capsule
S1: the preparation of colloid liquid: after getting all each component of colloid ready, water 52Kg is put into heating tank, is heated to boiling After rising, sodium alginate 7Kg, konjaku flour 5Kg is added, and continue stirring until boiling with glass bar, stops heating after 8 minutes, by glue Matter liquid be put into cooling system be cooled to 65-75 DEG C it is spare.
S2: quality raw materials, PORPHYRIN IRON 12Kg, vitamin e1 3Kg, vitamin B are chosen1215Kg, spinach extract 27Kg, fill Divide spare after mixing.
S3: preferred enzyme preparation, cellulase 3Kg, protease 2Kg, amylase 4Kg, 1,4 beta-glucanase 3Kg are sufficiently mixed It is spare after uniformly.
S4: preferred probiotics, Bifidobacterium 3Kg, lactobacillus acidophilus 5Kg, it is spare after being sufficiently mixed uniformly.
S5: whole milk 11Kg, oligosaccharide 4Kg, degreasing yellow meal worm powder 5Kg, whey powder 2Kg, blood are got all the in nutrient solution preparation ready Slurry protein powder 4Kg, lecithin 6Kg, seawood meal 5Kg, calcium citrate 0.4Kg, sodium alginate 0.3Kg, saccharin 0.4Kg, sorbic acid It is spare to all substances whole dissolution to be put into stirring in container by 0.09Kg, water 58Kg.
S6: mixed liquor allotment takes the nutrient solution 43Kg of mixture 5Kg and step S5 obtained by mixture 4Kg, S3 of step S2 It pours into blending tank, continues stirring until and uniformly filter out the substance and impurity not being completely dissolved with 80 mesh filter screens, it is molten by what is obtained The mixture 6Kg of liquid and step S4 mix well to obtain mixed liquor.
S7: the step S6 mixed liquor formed is delivered in the container of automation titration device by coating, and by step S1 system Standby colloid liquid is delivered in the cyclone vessel below titration device, starts and run titration system, and machine upper container mixes It closes liquid to instill below machine in cyclone vessel through titration kit, 8-12 minutes under eddy flow state, colloid liquid is just in titration at pearl The outside of the mixing titration drop of shape forms one layer of coating to get pearl shape capsule particle has been arrived.
It is cleaned after coating, the satisfactory precious Beads of membrane wrapping thickness is transferred to cleaning system, utilize rolling Ladder type conveyer belt is rolled with pure water and is rinsed 3-6 times, to obtain the more regular pearl shape capsule particle of surface more smooth form.Clearly It also needs to sterilize after washing, the pearl shape capsule particle after cleaning is put into sterilization kettle, sterilizes 20-25 at a temperature of 72-76 DEG C Minute after be cooled to room temperature to get.
Comparative example 1:
Compared with Example 1, spinach extract is free of, other operations are same as Example 1.
Comparative example 2:
Compared with Example 1, compound micro-ecological preparation is free of, other operations are same as Example 1.
Comparative example 3:
Compared with Example 1, enzyme-containing formulation, other operations are not same as Example 1.
Comparative example 4:
Compared with Example 1, the content of nutrient solution raw materials is different, and other operating procedures are same as Example 1.Concrete content It is as follows:
Whole milk 9Kg, oligosaccharide 2Kg, degreasing yellow meal worm powder 8Kg, whey powder 1Kg, plasma protein powder 2Kg, lecithin 2Kg, seawood meal 3Kg, calcium citrate 0.2Kg, sodium alginate 0.2Kg, saccharin 0.2Kg, sorbic acid 0.06Kg, water 50Kg.
Performance test
The piglet that embodiment 1-4 and comparative example 1-4 are finally prepared is subjected to relevant property with pearl shape blood enriching capsule It can test.Testing program: choosing health, 21 age in days weanling pigs similar in weight, is randomly divided into 9 groups, every group of 3 repetitions, often A repetition 10, experimental period are that wean starts to terminate within 30 days to wean.Test period: for 12 days 13 days-July of June in 2018, examination Test place: Ganzhou.Guarantee rearing conditions and the raisings such as daylighting, ventilation, temperature and humidity, cultured space and the density of every group of piglet Facility is same or similar, and poultry raiser's management level will be also consistent as far as possible.Feeding method: daily feeding 3 times, blank group is base Plinth daily ration, test group add 5% piglet pearl shape blood enriching capsule in basal diet.
Testing index and method are as follows: utilize URIT-15 Hemoglobin Meter, respectively before the test with piglet ear is taken after test Edge vein hematometry piglet hemoglobin concentration, and record piglet growth, diarrhea and extremely wash in a pan situation, collect data and use SPSS17.0 statistics, is as a result indicated with " average value ± standard error ", significance 0.05.Test result is as shown in table 1.
Table 1
Note: digital shoulder marking-up is female in table, horizontally-arranged different expressions significant difference (P < 0.05)
As can be seen from Table 1, the piglet that 1-4 of the embodiment of the present invention is obtained is compared comparative example 1- with pearl shape blood enriching capsule 4 and blank group, the hemoglobin concentration of weanling pig can be significantly improved, feed intake, weight gain obviously increase, diarrhea rate death and culling rate It reduces.Compared with Example 1, comparative example 1 is free of spinach extract, and comparative example 2 is free of compound micro-ecological preparation, and comparative example 3 is not Enzyme-containing formulation, the content of nutrient solution raw materials is different in comparative example 4;At these four, obtained blood enriching capsule compares this hair Bright embodiment 1, improve hemoglobin concentration, feed intake, weight gain the effect of on declined, while feedstuff-meat ratio, diarrhea rate, Death and culling rate also increased.Therefore, piglet of the invention is selected and is contained by each raw material in formula with pearl shape blood enriching capsule Amount proportion, makes to act synergistically between ingredient, can adjust enteron aisle, promotes intestinal health development, improves hematopoietic potential and the son of piglet The immunity of pig.
According to the disclosure and teachings of the above specification, those skilled in the art in the invention can also be to above-mentioned embodiment party Formula is changed and is modified.Therefore, the invention is not limited to the specific embodiments disclosed and described above, to the one of invention A little modifications and changes should also be as falling into the scope of the claims of the present invention.In addition, although being used in this specification Some specific terms, these terms are merely for convenience of description, does not limit the present invention in any way.

Claims (10)

1. a kind of piglet pearl shape blood enriching capsule, which is characterized in that it is 2- that the piglet, which is diameter with pearl shape blood enriching capsule, The pearl shape capsule particle body of 6mm, the capsule particle body include the liquid medicine core positioned at external gelatinous layer and inside;Institute It states gelatinous layer to be prepared by the raw material of following mass parts: 45-55 parts of water, 3-9 parts of sodium alginate, 3-9 parts of konjaku flour, the liquid Body medicine core is prepared by the raw material of following mass parts: 4-6 parts of the factor of enriching blood, 4-6 parts of complex enzyme formulation, compound micro-ecological preparation 4-6 parts, nutrient solution and 35-45 parts of antistaling and antiseptic agent;
The complex enzyme formulation is made of the raw material of following mass parts: 2-5 parts of cellulase, 2-5 parts of protease, amylase 2-5 Part, 2-5 parts of 1,4 beta-glucanase;The compound micro-ecological preparation includes the raw material of following mass parts: 3-6 parts of Bifidobacterium, acidophilus 3-6 parts of lactobacillus.
2. piglet pearl shape blood enriching capsule according to claim 1, which is characterized in that the nutrient solution and antistaling and antiseptic agent It is made of the raw material of following mass parts: 10-15 parts of whole milk, 3-9 parts of oligosaccharide, 3-9 parts of degreasing yellow meal worm powder, whey powder 1- 3 parts, 2-6 parts of plasma protein powder, 3-6 parts of lecithin, 3-7 parts of seawood meal, 0.2-0.6 parts of calcium citrate, sodium alginate 0.2-0.6 Part, 0.2-0.6 parts of saccharin, 0.06-0.12 parts of sorbic acid, 50-60 parts of water.
3. piglet pearl shape blood enriching capsule according to claim 2, which is characterized in that the nutrient solution and antistaling and antiseptic agent It is made of the raw material of following mass parts: 12.5 parts of whole milk, 6 parts of oligosaccharide, 6 parts of degreasing yellow meal worm powder, 2 parts of whey powder, blood 4 parts of slurry protein powder, 4.5 parts of lecithin, 5 parts of seawood meal, 0.4 part of calcium citrate, 0.4 part of sodium alginate, 0.4 part of saccharin, sorb 0.09 part, 55 parts of water of acid.
4. piglet according to claim 1 or claim 2 pearl shape blood enriching capsule, which is characterized in that the factor of enriching blood is by following The raw material of mass parts forms: 10-16 parts of PORPHYRIN IRON, 0-16 parts of vitamin e1, vitamin B1210-16 parts, spinach extract 20-30 Part.
5. piglet pearl shape blood enriching capsule according to claim 4, which is characterized in that the factor of enriching blood is by following quality The raw material composition of part: 13 parts of PORPHYRIN IRON, 3 parts of vitamin e1, vitamin B1213 parts, 25 parts of spinach extract.
6. piglet pearl shape blood enriching capsule according to claim 1, which is characterized in that the complex enzyme formulation is by following matter Measure the raw material composition of part: 3.5 parts of cellulase .5 parts of protease 3,3.5 parts of amylase, 3.5 parts of 1,4 beta-glucanase.
7. piglet pearl shape blood enriching capsule according to claim 1, which is characterized in that the compound micro-ecological preparation includes The raw material of following mass parts: 4.5 parts of Bifidobacterium, 4.5 parts of lactobacillus acidophilus.
8. the preparation method of any piglet pearl shape blood enriching capsule of claim 1-7, which is characterized in that including walking as follows It is rapid:
S1: the preparation of colloid liquid: water is put into heating tank, sodium alginate, konjaku flour is added after being heated to boiling, and use glass Stick continues stirring until boiling, after 8-10 minutes stop heating, by colloid liquid be put into cooling system be cooled to 65-75 DEG C it is spare;
S2: PORPHYRIN IRON, vitamin E, vitamin B are chosen12, spinach extract, be sufficiently mixed uniformly after it is spare;
S3: choosing cellulase, protease, amylase, 1,4 beta-glucanase, spare after being sufficiently mixed uniformly;
S4: selecting probiotics Bifidobacterium, lactobacillus acidophilus, spare after being sufficiently mixed uniformly;
S5: nutrient solution preparation, get all the ready whole milk, oligosaccharide, degreasing yellow meal worm powder, whey powder, plasma protein powder, lecithin, It is spare to all substances whole dissolution to be put into stirring in container for seawood meal, calcium citrate, sodium alginate, saccharin, sorbic acid, water;
S6: mixed liquor allotment pours into the nutrient solution of mixture obtained by step S2, S3 and step S5 in blending tank, lasting to stir To uniform, the substance and impurity not being completely dissolved are filtered out with 60-80 mesh filter screen, by the mixture of obtained solution and step S4 It mixes well to obtain mixed liquor;
S7: the step S6 mixed liquor formed is delivered in the container of automation titration device by coating, and prepared by step S1 Colloid liquid is delivered in the cyclone vessel below titration device, starts and run titration system, the mixed liquor of machine upper container It is instilled below machine in cyclone vessel through titration kit, 8-12 minutes under eddy flow state, colloid liquid is just in titration at perlarious The outside of mixing titration drop forms one layer of coating to get pearl shape capsule particle has been arrived.
9. the preparation method of piglet pearl shape blood enriching capsule according to claim 8, which is characterized in that need to also be into after coating The satisfactory precious Beads of membrane wrapping thickness are transferred to cleaning system by row cleaning, using rolling ladder type conveyer belt with pure Water, which rolls, to be rinsed 3-6 times, to obtain the pearl shape capsule particle of surface smooth form rule.
10. the preparation method of piglet pearl shape blood enriching capsule according to claim 9, which is characterized in that also needed after cleaning It sterilizes, the pearl shape capsule particle after cleaning is put into sterilization kettle, it is cold after being sterilized 20-25 minutes at a temperature of 72-76 DEG C But to room temperature.
CN201910024348.7A 2019-01-10 2019-01-10 A kind of piglet pearl shape blood enriching capsule and preparation method thereof Pending CN109645242A (en)

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