CN109568209A - A kind of anti-ageing crease-resistant compact essential oils - Google Patents

A kind of anti-ageing crease-resistant compact essential oils Download PDF

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Publication number
CN109568209A
CN109568209A CN201910017107.XA CN201910017107A CN109568209A CN 109568209 A CN109568209 A CN 109568209A CN 201910017107 A CN201910017107 A CN 201910017107A CN 109568209 A CN109568209 A CN 109568209A
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China
Prior art keywords
extract
essential oils
component
skin
thallus laminariae
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Granted
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CN201910017107.XA
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Chinese (zh)
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CN109568209B (en
Inventor
梁活玲
李继德
胡家逢
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Guangzhou Yue Cosmetics Co., Ltd.
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SHANGHAI YUEMU COSMETICS Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of anti-ageing crease-resistant compact essential oils, mainly contain the component of following weight percentage: Crithmum maritimum extract 0.1-1%, wing algae extract 0.1-1%, Herba Cancriniae lasiocarpae flower extract 0.1-1%, thallus laminariae extract 0.1-1%.After four rationally compound, improve local organization, the living environment of cell rapidly by affinity interaction plant extracts bioactive molecule, accelerate its metabolism, comprehensively solve is because of some problems caused by local metabolic obstacle, promote cell metabolism and cytothesis function, it can be obviously improved skin wrinkle problem, there is significant crease-resistant, anti-ageing, tightening effect.

Description

A kind of anti-ageing crease-resistant compact essential oils
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of anti-ageing crease-resistant compact essential oils.
Background technique
With advancing age and the increasing of environmental pollution and life stress, the skin aging of people are more and more obvious, Crease-resistant compact beauty and skin care is also increasingly valued by people.Skin aging is usually expressed as skin elasticity reduction, skin wrinkle Line is added, the roughness of skin increases, moistens remitted its fury etc..Simple use moisturizer skin care is for prevention in daily life Skin aging is clearly inadequate.Other natural causes such as environment, sunlight and pressure etc. can also promote skin ageing to accelerate, at this moment It waits skin and also is easy spot, phenomena such as microgroove.The years can cause body ages simultaneously, and skin metabolism slows down, the glue of skin Former albumen and elastic fibrous tissue fiber change, and reduce texture and content, skin gradually lose elasticity, become loose, wrinkle goes out It is existing.
On the market mostly with aqua or oil-in-water product for anti-ageing crease-resistant compact product, therefore it is necessary to research and development are a pure Oil product, using oil-soluble plant extracts as the anti-ageing crease-resistant compact product of effective component.
Summary of the invention
Based on this, the purpose of the present invention is to provide a kind of anti-ageing crease-resistant compact essential oils.
A kind of anti-ageing crease-resistant compact essential oils, mainly contain the component of following weight percentage:
Crithmum maritimum extract 0.1-1%
Wing algae extract 0.1-1%
Herba Cancriniae lasiocarpae flower extract 0.1-1%
Thallus laminariae extract 0.1-1%.
The entitled Crithmum maritimum (CRITHMUM MARITIMUM) of cosmetics Chinese of Crithmum maritimum extract of the present invention mentions Object is taken, indicates that oil-soluble prepared by extraction mentions from plant-Crithmum maritimum on a kind of rock for being grown in and being exposed in wave Object is taken, can be contained or including one or more bioactive molecules, including glycolipid, oleic acid, erucic acid and phytosterol.It closes Suitable Crithmum maritimum extract may include NATIVE ESSENCE (from BiotechMarine company, France).
The entitled algae extract of cosmetics Chinese of wing algae extract of the present invention, indicates from wing algae made from extraction Oil soluble extract can contain or including one or more bioactive molecules, including glycolipid, polypeptide.Suitable wing Algae extract may include KALPARIANE AD (from BiotechMarine company, France).
The entitled Herba Cancriniae lasiocarpae (SPILANTHES ACMELLA) of cosmetics Chinese of Herba Cancriniae lasiocarpae flower extract of the present invention Flower extract indicates oil soluble extract obtained by extracting from the flower of Herba Cancriniae lasiocarpae plant, and effective component is mainly alkylamide. Suitable Herba Cancriniae lasiocarpae flower extract may include that GATULINE IN-TENSE(comes from good method lion (Gattefoss é) company.
The entitled thallus laminariae (UNDARIA PINNATIFIDA) of cosmetics Chinese of thallus laminariae extract of the present invention mentions Take object, indicate the oil soluble extract obtained from extracting in thallus laminariae, main component be polyphenol with antioxidation, The substances such as flavones can contain EPHEMERTM(coming from BiotechMarine company, France).
In wherein some embodiments, the anti-ageing crease-resistant compact essential oils can also contain containing following quality percentage The component of amount: tocopherol acetate 0.1-2%.
In wherein some embodiments, the anti-ageing crease-resistant compact essential oils can also contain containing following quality percentage The component of amount: caprylic/capric triglyceride 94-99.5%.
In wherein some embodiments, the anti-ageing crease-resistant compact essential oils contain the group of following mass percentage Point: Crithmum maritimum extract 0.1%, wing algae extract 1%, Herba Cancriniae lasiocarpae flower extract 0.1%, thallus laminariae extract 1%, caprylic/capric Triglycerides 95.8%, tocopherol acetate 2%.
In wherein some embodiments, the anti-ageing crease-resistant compact essential oils contain the group of following mass percentage Point: Crithmum maritimum extract 0.5%%, wing algae extract 0.5%, Herba Cancriniae lasiocarpae flower extract 0.5%, thallus laminariae extract 0.5%, octanoic acid/ Triglyceride DDD 96%, tocopherol acetate 2%.
The present invention has the advantage that and the utility model has the advantages that
(1) present invention use oil-soluble plant extracts, using thallus laminariae extract contain antioxidant, have immediately with it is long-acting Inoxidizability, less free radical achievees the effect that anti-ageing.Contain glycolipid, oleic acid, erucic acid and plant using Crithmum maritimum extract Sterols can promote the synthesis of ceramide and silk polyprotein, anti-lipid peroxidation and inflammatory reaction, rebuild water balance, Increase skin shine.Contained elastomer network (protein and polysaccharide) using wing algae extract, is reduced early in senile cell Decline the synthesis of albumen, maintains the integrality of tissue, guarantees cyto-architectural adhesiveness and the degree of packing.Utilize Herba Cancriniae lasiocarpae flower extract Containing alkylamide, fibroblastic natural vigour can be excited, promotes fibroblastic movement and contraction, it is brilliant to increase collagen The density of shape network internal, compact skin.
(2) the anti-ageing crease-resistant compact essential oils of the present invention carry out the percutaneous water loss value of skin (TEWL value) experiment test, Also there is good water lock moistening effect as the result is shown, can be applied to dry skin or water deficient skin, play good moisturizing Effect.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below Step ground detailed description.Embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to Routine techniques carries out.
Experimental group 1
A kind of anti-ageing crease-resistant compact essential oils, the component containing following weight percentage:
Crithmum maritimum extract 0.1%, wing algae extract 1%, Herba Cancriniae lasiocarpae flower extract 0.1%, thallus laminariae extract 1%, caprylic/capric Triglycerides 95.8%, tocopherol acetate 2%.
Experimental group 2
A kind of anti-ageing crease-resistant compact essential oils, the component containing following weight percentage:
Crithmum maritimum extract 1%, wing algae extract 0.1%, Herba Cancriniae lasiocarpae flower extract 1%, thallus laminariae extract 0.1%, caprylic/capric Triglycerides 95.8%, tocopherol acetate 2%.
Experimental group 3
A kind of anti-ageing crease-resistant compact essential oils, the component containing following weight percentage:
It is Crithmum maritimum extract 0.5%%, wing algae extract 0.5%, Herba Cancriniae lasiocarpae flower extract 0.5%, thallus laminariae extract 0.5%, pungent Acid/Triglyceride DDD 96%, tocopherol acetate 2%.
Blank group
A kind of simple basis is free of the essential oils of other active matters, and the component containing following weight percentage: caprylic/capric is sweet Oily three esters 98%, tocopherol acetate 2%.
Control group 1
A kind of essential oils, the component containing following weight percentage: thallus laminariae extract 2%, caprylic/capric triglyceride 96%, tocopherol acetate 2%.
Control group 2
A kind of essential oils, the component containing following weight percentage: Crithmum maritimum extract 2%, caprylic/capric triglyceride 96%, tocopherol acetate 2%.
Control group 3
A kind of essential oils, the component containing following weight percentage: algae extract 2%, caprylic/capric triglyceride 96%, life Educate phenol acetic acid esters 2%.
Control group 4
A kind of essential oils, the component containing following weight percentage: Herba Cancriniae lasiocarpae flower extract 2%, caprylic/capric triglyceride 96%, tocopherol acetate 2%.
Control group 5
A kind of essential oils, the component containing following weight percentage: thallus laminariae extract 0.7%, Crithmum maritimum extract 0.7%, Algae extract 0.7%, caprylic/capric triglyceride 95.9%, tocopherol acetate 2%.
Control group 6
A kind of essential oils, the component containing following weight percentage: Herba Cancriniae lasiocarpae flower extract 0.7%, Crithmum maritimum extract 0.7%, algae extract 0.7%, caprylic/capric triglyceride 95.9%, tocopherol acetate 2%.
Control group 7
A kind of essential oils, the component containing following weight percentage: Herba Cancriniae lasiocarpae flower extract 0.7%, thallus laminariae extract 0.7%, algae extract 0.7%, caprylic/capric triglyceride 95.9%, tocopherol acetate 2%.
Control group 8
A kind of essential oils, the component containing following weight percentage: Herba Cancriniae lasiocarpae flower extract 0.7%, thallus laminariae extract 0.7%, Crithmum maritimum extract 0.7%, caprylic/capric triglyceride 95.9%, tocopherol acetate 2%.
Test 1 security test
The experiment of human body patch
Select 150 healthy volunteers, the age 25-60 years old, wherein especially select 120 35-60 years old and face wrinkles it is bright Aobvious, skin elasticity difference volunteer.Men and women is unlimited, is divided into 2 groups, every group of 60 people, everyone does 6 samples, selection standard spot tester (north Capital is happy to be reached), with enclosed patch test method, tested material about 0.020-0.025g is put into spot tester cell, be pasted on by It is surveyed in examination person's arm, spot tester is removed after 24 hours, respectively at 0.5 hour, 6 hours, 12 hours, 24 hours, 48 hours Dermoreaction is observed, records its result by skin closure type patch test dermoreaction grade scale in table 1.Selected volunteer It complies with standard.
1 skin closure type patch test dermoreaction grade scale of table
Table 2-3 patch test record
2 test data sheet of table
3 test data sheet of table
As table 2, table 3 as it can be seen that 120 volunteers through the invention described in blank group, control group 1-8, experimental group 1-3 spot Patch test, illustrates in the present invention in observation dermoreaction in 0.5,6,12,24,48 hour wherein 0 skin adverse reaction occurs The blank group, control group 1-8, experimental group 1-3 are safe.
Test 2 crowds test on probation
2.1 flexibility test
The aspiration that tested volunteer: selecting above-mentioned 120 especially selected 35-60 years old and face wrinkles are obvious, skin elasticity is poor Person is divided into 12 groups at random.
Given the test agent: sample made from heretofore described blank group, control group 1-8 and experimental group 1-3.
Application method: after the daily morning and evening face cleaning cleaning face of volunteer, given the test agent 2-3 drop palm of the hand in palm is taken to rub with the hands Heat coats entire face with double palms and presses lightly on to absorption.Other unusable products of period.Continuous use 4 weeks, weekly Skin elasticity is carried out to volunteer, skin is percutaneously lost, face imaging texture wrinkle analysis.Record 0 week, 1 week, 2 weeks, 3 weeks, 4 All results.
Test environment: the tested preceding clear water of volunteer cleans up face, to be 22 ± 2 DEG C in temperature, and relative humidity 50 ± In the environment of 2%RH, tested after waiting 30min.
Test equipment and index: skin elasticity tester MPA580(Germany CK) the facial elastic index R2 of detection, measurement 3 It is secondary to be averaged, the springback capacity of skin and there is the ratio between maximum tension amount of negative pressure when R2 value refers to no negative pressure, R value is said closer to 1 Bright skin elasticity is better.
Change rate %=(R valueAfter use- R valueBefore use)/R valueBefore use*100%
4 skin elasticity R2 value change rate number record of table
5 skin elasticity R2 value change rate number record of table
By table 4, table 5 as it can be seen that heretofore described experimental group 1-3, volunteer is after using 4 weeks, the variation of skin elasticity R2 value Rate is all larger than 10%, and experimental group 1-3 skin elasticity R2 value change rate is faster than blank group, control group 1-8, illustrates, the present invention makes The molten plant Crithmum maritimum extract of oil, wing algae extract, Herba Cancriniae lasiocarpae flower extract, thallus laminariae extract are shared with extensive Multiple skin elasticity, the effect of compact skin.
By experimental group 1-3 and control group 1-8 comparison it is found that when the molten plant Crithmum maritimum extract of oil, wing algae extract, golden button Button flower extract, thallus laminariae extract lack with one of component or a component are applied alone, and effect is all undesirable.
The percutaneous water loss value of 2.2 skins (TEWL value) test
Use skin water loss instrument TewameterTM300(Germany CK), divided by being percutaneously lost TEWL value to skin Analysis, TEWL value is smaller, illustrates that skin condition is better.
Change rate %=(TEWL valueAfter use- TEWL valueBefore use)/TEWL valueBefore use*100%
6 skin of table is percutaneously lost TEWL value change rate record
7 skin of table is percutaneously lost TEWL value change rate record
By table 6, table 7 as it can be seen that heretofore described experimental group 1-3, volunteer 4 weeks after use, TEWL value change rate was small In -15%, and experimental group 1-3 TEWL value change rate is faster than blank group, control group 1-8, illustrates the molten plant of oil that the present invention uses The essential oils that object Crithmum maritimum extract, wing algae extract, Herba Cancriniae lasiocarpae flower extract, thallus laminariae extract compound have drop The effect of low skin water loss.
2.3 VISIA image analysis wrinkles, the test of texture score value
(front, 45 ° of left side, 45 ° of right side direction) is taken pictures to volunteer's face using VISIA face-image analysis system, It is analyzed for wrinkle, texture two score values, score value is lower, and wrinkle of skin, texture are more unobvious.
Change rate %=(VISIA score valueAfter use- VISIA score valueBefore use)/VISIA score valueBefore use*100%
8 face-image of table analyzes wrinkle, texture score value change rate record
9 face-image of table analyzes wrinkle, texture score value change rate record
By table 8, table 9 as it can be seen that heretofore described experimental group 1-3, volunteer 4 weeks after use, wrinkle, texture score value changed Rate is respectively less than -15%, and experimental group 1-3 wrinkle, texture variations rate are faster than blank group, control group 1-8, illustrate use of the present invention The molten plant Crithmum maritimum extract of oil, wing algae extract, Herba Cancriniae lasiocarpae flower extract, thallus laminariae extract there is synergistic work With the essential oils compounded have the effect of less wrinkle texture.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.

Claims (5)

1. a kind of anti-ageing crease-resistant compact essential oils, which is characterized in that mainly contain the component of following weight percentage:
Crithmum maritimum extract 0.1-1%
Wing algae extract 0.1-1%
Herba Cancriniae lasiocarpae flower extract 0.1-1%
Thallus laminariae extract 0.1-1%.
2. essential oils according to claim 1, which is characterized in that also contain the component of following mass percentage: fertility Phenol acetic acid esters 0.1-2%.
3. essential oils according to claim 1 or 2, which is characterized in that also contain the component of following mass percentage: pungent Acid/Triglyceride DDD 94-99.5%.
4. essential oils according to claim 1, which is characterized in that the essential oils contain following mass percentage Component: Crithmum maritimum extract 0.1%, wing algae extract 1%, Herba Cancriniae lasiocarpae flower extract 0.1%, thallus laminariae extract 1%, the octanoic acid/last of the ten Heavenly stems Acid glycerol three ester 95.8%, tocopherol acetate 2%.
5. essential oils according to claim 1, which is characterized in that the essential oils contain following mass percentage Component: Crithmum maritimum extract 0.5%%, wing algae extract 0.5%, Herba Cancriniae lasiocarpae flower extract 0.5%, thallus laminariae extract 0.5%, pungent Acid/Triglyceride DDD 96%, tocopherol acetate 2%.
CN201910017107.XA 2019-01-08 2019-01-08 Anti-aging, anti-wrinkle and firming essence oil Active CN109568209B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110448486A (en) * 2019-08-14 2019-11-15 广州睿晞生化科技有限公司 It is a kind of to repair the impaired essential oils of sebum film
FR3102059A1 (en) * 2020-12-29 2021-04-23 Algologie Cosmetic compositions to fight against environmental pollution

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CN101816624A (en) * 2010-05-06 2010-09-01 广州法施兰化妆品有限公司 Moisturizing cosmetic and preparation method thereof
CN106794214A (en) * 2014-10-20 2017-05-31 瓦尔比奥蒂斯公司 The composition of the mixture of contained molecule in mixture containing plant extracts or the plant, and for controlling the purposes of carbohydrate and/or lipid-metabolism
CN107334725A (en) * 2017-08-08 2017-11-10 广州蜜妆生物科技有限公司 A kind of anti-ageing American's flesh facial mask of Crithmum maritimum
CN107468582A (en) * 2017-09-12 2017-12-15 上海馥优化妆品有限公司 One kind is compacted anti-wrinkle eye shadow and preparation method thereof
CN107567329A (en) * 2015-03-05 2018-01-09 路博润先进材料公司 The extractive from fermentative of cot penicillium and its beautifying use
CN108853000A (en) * 2018-08-17 2018-11-23 广州皓雨投资有限公司 Have effects that moisture-keeping crease-shedding restores the composition of elasticity of skin, facial mask and preparation method thereof
CN109106651A (en) * 2018-10-11 2019-01-01 圣凯西(上海)生物科技有限公司 A kind of compact frost of anti-wrinkle and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101816624A (en) * 2010-05-06 2010-09-01 广州法施兰化妆品有限公司 Moisturizing cosmetic and preparation method thereof
CN106794214A (en) * 2014-10-20 2017-05-31 瓦尔比奥蒂斯公司 The composition of the mixture of contained molecule in mixture containing plant extracts or the plant, and for controlling the purposes of carbohydrate and/or lipid-metabolism
CN107567329A (en) * 2015-03-05 2018-01-09 路博润先进材料公司 The extractive from fermentative of cot penicillium and its beautifying use
CN107334725A (en) * 2017-08-08 2017-11-10 广州蜜妆生物科技有限公司 A kind of anti-ageing American's flesh facial mask of Crithmum maritimum
CN107468582A (en) * 2017-09-12 2017-12-15 上海馥优化妆品有限公司 One kind is compacted anti-wrinkle eye shadow and preparation method thereof
CN108853000A (en) * 2018-08-17 2018-11-23 广州皓雨投资有限公司 Have effects that moisture-keeping crease-shedding restores the composition of elasticity of skin, facial mask and preparation method thereof
CN109106651A (en) * 2018-10-11 2019-01-01 圣凯西(上海)生物科技有限公司 A kind of compact frost of anti-wrinkle and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110448486A (en) * 2019-08-14 2019-11-15 广州睿晞生化科技有限公司 It is a kind of to repair the impaired essential oils of sebum film
CN110448486B (en) * 2019-08-14 2021-06-11 广州睿晞生化科技有限公司 Essential oil capable of repairing damaged sebum membrane
FR3102059A1 (en) * 2020-12-29 2021-04-23 Algologie Cosmetic compositions to fight against environmental pollution

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