CN109566826A - 一种抗衰老提高免疫力美容的组合物 - Google Patents
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Abstract
本发明属于食品领域，涉及一种抗衰老，提高免疫力，美容的组合物。其原料及重量份数组分如下：烟酰胺腺嘌呤二核苷酸(NAD+)0.5‑1份、L‑蛋氨酸0.5‑1份，牛磺酸0.5‑1份，山楂粉3‑10份，葡萄糖3‑10份，枸杞子提取物3‑10份，菊花提取物3‑10份，玫瑰茄(洛神花)提取物3‑10份。
Description
技术领域
本发明涉及一种抗衰老，提高免疫力，美容的组合物。其特征在于，烟酰胺腺嘌呤二核苷酸(NAD+)、L-蛋氨酸，牛磺酸，山楂粉，葡萄糖，枸杞子提取物，菊花提取物，玫瑰茄(洛神花)提取物。
技术背景
目前市面上的抗衰老，提高免疫力，美容产品多数为食品或中药的提取物组合而成，一定程度上具有增强人体机能的作用，但是使用效果许多并不理想，功效有待加强。
衰老，是指机体各器官功能普遍的、逐渐降低的过程。衰老有两种不同的情况，一种是正常情况下出现的生理性衰老；另一种是疾病引起的病理性衰老。是一种自然规律。但是，当人们采用良好的生活***衡，均会导致和加快衰老，表现为精神不振、健忘、形寒肢冷、纳差少眠、腰膝无力、发脱齿摇、气短乏力，甚则面浮肿等。千百年来，人们一直在探索健康长寿的奥秘，充满对青春长驻、延年益寿的向往。
目前社会竞争激烈，生活节奏快，生活压力大，很多上班族长期处于激烈的竞争条件下，生活作息不规律，饮食不均衡，导致身体处于亚健康状态，免疫功能低下，免疫力的降低极大的影响了人体的健康，导致各种疾病的发生。目前，中国已经进入老龄化社会。随着年龄的增长，老年人自身的免疫力下降，身体各功能容易衰老，从而引发各种疾病。因此，需要延缓老年人体质下降、提高免疫力、降低高血脂、高血糖、高血压，有效提高老年人的身体免疫功能。
当今空气污染和紫外线越发严重地刺激和损伤人的皮肤，，表现为皮肤暴露部位粗糙略显肥厚、皱纹加深加粗、皮肤角质增厚、不规则性色素沉着、毛细血管扩张或消失、表皮角化不良及真皮弹性纤维变性等。目前随着人们生活水平提高，对外貌的要求也越来越高，因此，抗衰老护肤将是将来一个持续的发展趋势。
随着人们消费水平的日益提高，消费者在关注食品功效性的基础之上，更注重其天然性。中药来源的天然成分具有无毒、温和、高效等优点。研制一种天然绿色的抗衰老，提高免疫力，美容的产品成为当前人们的迫切需要。
发明内容
本发明提供了一种抗衰老，提高免疫力，美容的组合物。
为了实现上述发明目的，本发明提供以下技术方案：
本发明提供了一种抗衰老，提高免疫力，美容的组合物：烟酰胺腺嘌呤二核苷酸0.5-1份、L-蛋氨酸0.5-1份，牛磺酸0.5-1份，山楂粉3-10份，葡萄糖3-10份，枸杞子提取物3-10份，菊花提取物3-10份，玫瑰茄(洛神花)提取物3-10份。
本发明组合物中的NAD+属于人体必需的辅酶，并且人体可以自己合成。L-蛋氨酸，牛磺酸，山楂粉，葡萄糖，枸杞子提取物，菊花提取物，玫瑰茄(洛神花)提取物为药食同源的食物。
NAD+和L-蛋氨酸：NAD+是许多脱氢酶的辅酶，脱氢酶氧化产生的氢传递给NAD+，使之成为NADH。它在糖酵解，糖异生，三羧酸循环和呼吸链中发挥着不可替代的作用。人体中存在一种修复人体DNA的蛋白质PARP1，蛋白质PARP1可以修复人体DNA，在人体代谢的过程中DBC1的蛋白质侵蚀PARP1，使其失去修复DNA的能力，导致人体逐渐衰老。NAD+则可以抑制DBC1与PARP1起反应。NAD+辅助抗衰老蛋白质SIRT1和修复蛋白质PARP1的过程中会不断生成烟酰胺，烟酰胺是SIRT1和PARP1的抑制剂，过度堆积会导致抗衰老蛋白质SIRT1和PARP1活性下降。而烟酰胺通过体内代谢变成N-甲基4吡啶酮3甲酰胺和N-甲基2吡啶酮5甲酰胺，这两个反应都需要大量甲基参与反应。加入L-蛋氨酸即甲基供体可以加速烟酰胺代谢进程，防止烟酰胺的堆积对两种蛋白质活性造成影响。
牛磺酸：作为人体必不可少的营养素，其最显著的作用就是抗疲劳、增强体质和免疫力，此外还具有提高神经传导和视觉机能、缓解视觉疲劳、抑制血小板凝集、降低血脂、保持人体正常血压、防治动脉硬化、保护心肌细胞、抗心律失常的作用，对降低血液中胆固醇含量有特殊疗效，可促进脂类的吸收、抗氧化、抗衰老、改善记忆力、维持正常的生殖功能、降血糖、消炎、解热、镇痛以及促进婴幼儿脑组织和智力发育等作用，可用于治疗急慢性肝炎、脂肪肝、多种炎症、感冒、发烧、心力衰竭、高血压等。
山楂粉：具有降血脂、血压、强心、抗心律不齐等作用，同时也是健脾开胃、消食化滞、活血化痰的良药，对胸膈脾满、疝气、血淤、闭经等症有很好的疗效。山楂内的黄酮类化合物牡荆素，是一种抗癌作用较强的药物，其提取物对抑制体内癌细胞生长、增殖和浸润转移均有一定的作用。
葡萄糖：快速补充能量，加强记忆，刺激钙质吸收和增加细胞间的沟通。
枸杞子提取物：是一种营养丰富、功效显著的传统中药，其主要成分为枸杞多糖、甜菜碱、颠茄碱、天仙子胺、类胡萝卜素、多肽、黄酮、多种氨基酸、多种维生素及微量元素、玉蜀黍黄素、有机酸等，具有提高人体免疫力、抗疲劳、抗衰老、抗肿瘤、降压、降血糖、防治高血压和心脏病、动脉硬化等作用。
菊花提取物：味道稍苦，清热能力强，常用于散风热。具有疏风散热、养肝明目、清凉解毒的功能，可治伤风感冒、疔疮肿毒、血压偏高及动脉硬化等症。还具有清凉降火，明目醒脑，抗氧化，防衰老的功效。
玫瑰茄(洛神花)提取物：含有丰富的蛋白质、有机酸、多种氨基酸及维生素，有“植物红宝石”的美誉。具有清热解渴、养血活血、养颜美容，消除疲倦，改善便秘等作用，对皮肤粗糙、肤色黯淡都有帮助。
本发明优点：本发明直接补充人体中所需的NAD+，提高体内NAD+的水平，从而维持PARP1不被破坏，抗衰老。牛磺酸，枸杞子，洛神花提高人体免疫力，美容养颜。依据中西医相结合的理论，研究出的一种绿色天然，安全的食品组合物。
具体实施方式
实施例1
烟酰胺腺嘌呤二核苷酸500mg，L-蛋氨酸200mg，牛磺酸300mg，山楂粉200mg，葡萄糖1000mg，枸杞子提取物300mg，菊花提取物350mg，洛神花提取物400mg经混合，制粒，干燥，压片，制成压片糖果。
实施例2
烟酰胺腺嘌呤二核苷酸300mg，L-蛋氨酸150mg，牛磺酸200mg，山楂粉150mg，葡萄糖800mg，枸杞子提取物120mg，菊花提取物200mg，洛神花提取物300mg经混合，加入占总质量50％-60％的微晶纤维素，混合均匀，喷入95％乙醇溶液，制软材，过50目筛制粒，干燥后分装于胶囊中，制得胶囊剂型糖果。
实施例3
烟酰胺腺嘌呤二核苷酸600mg，L-蛋氨酸300mg，牛磺酸300mg，山楂粉3g，葡萄糖10g，枸杞子提取物5g，菊花提取物4g，洛神花提取物5g经混合匀，干燥，分装于铝箔袋中，制得固体饮料(凉水或者温水冲调后饮用)。
实施例4
烟酰胺腺嘌呤二核苷酸400mg，L-蛋氨酸300mg，牛磺酸300mg，山楂粉20mg，葡萄糖1500mg，枸杞子提取物500mg，菊花提取物400mg，洛神花提取物500mg，加入常规量的防腐剂，稳定剂等辅料，过滤、灭菌后分装10mL瓶中，制成口服液。
Claims (8)
1.一种抗衰老，提高免疫力，美容的组合物其特征在于，由烟酰胺腺嘌呤二核苷酸、L-蛋氨酸，牛磺酸、山楂粉，葡萄糖，枸杞子提取物，菊花提取物，玫瑰茄(洛神花)提取物等人体可以服用的药食同源的组分制成。
2.一种抗衰老，提高免疫力，美容的组合物。其原料及重量份数组分如下：烟酰胺腺嘌呤二核苷酸0.5-1份、L-蛋氨酸0.5-1份，牛磺酸0.5-1份，山楂粉3-10份，葡萄糖3-10份，枸杞子提取物3-10份，菊花提取物3-10份，玫瑰茄(洛神花)提取物3-10份。
3.如权利要求1所述的用于抗衰老，提高免疫力，美容的组合物。
4.如权利要求1至3中任一项所述的抗衰老，提高免疫力，美容的组合物。
5.根据权利要求1所述的抗衰老，提高免疫力，美容的组合物，其特征在于：所述烟酰胺腺嘌呤二核苷酸含量不大于1g。
6.根据权利要求1所述的抗衰老，提高免疫力，美容的组合物，其特征在于：所述L-蛋氨酸含量不超过0.7g。
7.任何含有烟酰胺腺嘌呤二核苷酸的抗衰老，提高免疫力，美容的食品和保健品。
8.根据权利要求1-7任意一项所述的抗衰老，提高免疫力，美容的组合物，其特征在于：组合物为口服制剂，包括固体饮料，压片糖果、胶囊剂型糖果、口服液。
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