CN109563039A - 一种羟尼酮的制备方法 - Google Patents
一种羟尼酮的制备方法 Download PDFInfo
- Publication number
- CN109563039A CN109563039A CN201780048603.0A CN201780048603A CN109563039A CN 109563039 A CN109563039 A CN 109563039A CN 201780048603 A CN201780048603 A CN 201780048603A CN 109563039 A CN109563039 A CN 109563039A
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- ethyl acetate
- methyl
- purification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
Description
Claims (10)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2016106425150 | 2016-08-08 | ||
CN201610642515.0A CN107698499A (zh) | 2016-08-08 | 2016-08-08 | 一种羟尼酮的制备方法 |
PCT/CN2017/095882 WO2018028508A1 (zh) | 2016-08-08 | 2017-08-03 | 一种羟尼酮的制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109563039A true CN109563039A (zh) | 2019-04-02 |
Family
ID=61161577
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610642515.0A Pending CN107698499A (zh) | 2016-08-08 | 2016-08-08 | 一种羟尼酮的制备方法 |
CN202310048439.0A Pending CN116082225A (zh) | 2016-08-08 | 2016-08-08 | 一种羟尼酮的制备方法 |
CN201780048603.0A Pending CN109563039A (zh) | 2016-08-08 | 2017-08-03 | 一种羟尼酮的制备方法 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610642515.0A Pending CN107698499A (zh) | 2016-08-08 | 2016-08-08 | 一种羟尼酮的制备方法 |
CN202310048439.0A Pending CN116082225A (zh) | 2016-08-08 | 2016-08-08 | 一种羟尼酮的制备方法 |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP6764999B2 (zh) |
CN (3) | CN107698499A (zh) |
WO (1) | WO2018028508A1 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111004173A (zh) * | 2019-12-31 | 2020-04-14 | 北京康蒂尼药业有限公司 | 一种羟尼酮的制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005047256A1 (fr) * | 2003-11-14 | 2005-05-26 | Shanghai Genomics, Inc. | Derives de pyridone, et utilisation correspondante |
CN101165051A (zh) * | 2007-08-07 | 2008-04-23 | 中国科学院长春应用化学研究所 | 树枝状主体材料及该化合物制备的有机电致发光器件 |
CN101723883A (zh) * | 2008-10-24 | 2010-06-09 | 上海睿星基因技术有限公司 | 一种羟尼酮的制备方法 |
CN102099036A (zh) * | 2008-06-03 | 2011-06-15 | 英特芒尼公司 | 用于治疗炎性疾患和纤维化疾患的化合物和方法 |
CN102766041A (zh) * | 2012-08-17 | 2012-11-07 | 济南大学 | 一种水杨醛衍生物中间体的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0129260D0 (en) * | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
PE20080150A1 (es) * | 2006-06-02 | 2008-04-11 | Janssen Pharmaceutica Nv | Derivados de piridinona n-aril y n-heteroaril sustituidos como antagonistas del receptor de la hormona concentradora de melanina (mch) |
ES2483866T3 (es) * | 2006-12-05 | 2014-08-08 | Janssen Pharmaceutica Nv | Derivados de diaza-espiro-piridinona sustituidos novedosos para uso en enfermedades mediadas por MCH-1 |
KR20090082484A (ko) * | 2006-12-14 | 2009-07-30 | 일라이 릴리 앤드 캄파니 | 5-[4-(아제티딘-3-일옥시)-페닐]-2-페닐-5h-티아졸로[5,4-c]피리딘-4-온 유도체 및 mch 수용체 길항제로서의 이들의 용도 |
AR092742A1 (es) * | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
AU2017213690A1 (en) * | 2016-02-01 | 2018-08-16 | 3M Innovative Properties Company | Adhesive compositions |
-
2016
- 2016-08-08 CN CN201610642515.0A patent/CN107698499A/zh active Pending
- 2016-08-08 CN CN202310048439.0A patent/CN116082225A/zh active Pending
-
2017
- 2017-08-03 CN CN201780048603.0A patent/CN109563039A/zh active Pending
- 2017-08-03 JP JP2019507241A patent/JP6764999B2/ja active Active
- 2017-08-03 WO PCT/CN2017/095882 patent/WO2018028508A1/zh active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005047256A1 (fr) * | 2003-11-14 | 2005-05-26 | Shanghai Genomics, Inc. | Derives de pyridone, et utilisation correspondante |
CN101165051A (zh) * | 2007-08-07 | 2008-04-23 | 中国科学院长春应用化学研究所 | 树枝状主体材料及该化合物制备的有机电致发光器件 |
CN102099036A (zh) * | 2008-06-03 | 2011-06-15 | 英特芒尼公司 | 用于治疗炎性疾患和纤维化疾患的化合物和方法 |
CN101723883A (zh) * | 2008-10-24 | 2010-06-09 | 上海睿星基因技术有限公司 | 一种羟尼酮的制备方法 |
CN102766041A (zh) * | 2012-08-17 | 2012-11-07 | 济南大学 | 一种水杨醛衍生物中间体的制备方法 |
Non-Patent Citations (1)
Title |
---|
能源部西安热工研究所主编: "《热工技术手册》", 30 June 1993 * |
Also Published As
Publication number | Publication date |
---|---|
CN116082225A (zh) | 2023-05-09 |
WO2018028508A1 (zh) | 2018-02-15 |
JP6764999B2 (ja) | 2020-10-07 |
CN107698499A (zh) | 2018-02-16 |
JP2019525946A (ja) | 2019-09-12 |
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Legal Events
Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20201105 Address after: 101300 Beijing city Shunyi District Linhe Industrial Development Zone Shun Kang Road No. 60 Applicant after: BEIJING CONTINENT PHARMACEUTICAL Co.,Ltd. Address before: 300308 Tianjin Binhai New Area Tianjin Free Trade Test Zone (Airport Economic Zone) No. 82 West Second Avenue Ligang Tower Skirt Room 201-B106 Applicant before: Tianjin Ruiying Biological Technology Co.,Ltd. |
|
TA01 | Transfer of patent application right | ||
CB02 | Change of applicant information |
Address after: 101300 No.60, Shunkang Road, Linhe Industrial Development Zone, Shunyi District, Beijing Applicant after: Beijing kangdini Pharmaceutical Co.,Ltd. Address before: 101300 No.60, Shunkang Road, Linhe Industrial Development Zone, Shunyi District, Beijing Applicant before: BEIJING CONTINENT PHARMACEUTICAL Co.,Ltd. |
|
CB02 | Change of applicant information |