CN109498509A - A kind of stoste and preparation method thereof with a variety of skin effects - Google Patents
A kind of stoste and preparation method thereof with a variety of skin effects Download PDFInfo
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- CN109498509A CN109498509A CN201811419104.0A CN201811419104A CN109498509A CN 109498509 A CN109498509 A CN 109498509A CN 201811419104 A CN201811419104 A CN 201811419104A CN 109498509 A CN109498509 A CN 109498509A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/49—Solubiliser, Solubilising system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The stoste and preparation method thereof with a variety of skin effects that the invention discloses a kind of, by weight percentage, specific formula component is as follows: water, Carbopol Ultrez U21, SEPIMAX ZEN, 1,3 propylene glycol, decoyl ketone, propylene glycol, Phenoxyethanol, TEA triethanolamine, vanillyl alcohol butyl ether, CO40, grapefruit essential oil, AQUAXYL, Liporeductl, HYDROVANCE, caffeine silanol, BN hydrolyze silk, De Minshu, sunset yellow, burnt sugar coloring;Stoste good penetrability of the invention easily absorbs, and clearly not sticky using rear face, whitening, moistening effect are good, promotes skin metabolism, and long-acting moisturizing, keeps skin water profit smooth, flexible;There is allergic phenomena in non-someone in whole subjects simultaneously, do not occur yet skin convulsion itch, shouting pain, the situations such as redness, therefore, the mild safety of the present invention can be used for a long time.
Description
Technical field
The present invention relates to Cosmetic Manufacture field, specifically a kind of stoste and its preparation side with a variety of skin effects
Method.
Background technique
" loving beauty is part of human nature " since having human civilization by oneself, has just there is the pursuit to beautification itself.In original society
Meeting, in sacrifice rites, animal fat can be smeared makes the colour of skin of oneself seem health and have light on the skin for some clans
Pool, this also earliest skin care behavior at last.It can be seen that the history of cosmetics can almost calculate that the presence from the mankind is opened
Begin.
Skin protection cosmetics is mainly to be formed by emulsifier by homogenization by this incompatible oil (phase) with water (phase),
But the emulsifier in traditional cosmetics is all compound, including various surfactants are all chemical synthesis, this was not both inconsistent
The psychological tendency to go back to nature is closed, does not also meet environmental requirement, and bring the stimulation to skin.In recent years, people are big
The lecithin and Tea Saponin extracted in soya-bean oil and plant of theaceae seed is used as emulsifier production cosmetics and obtains certain effect
Fruit, this is referred to as natural surfactant, is also can extract from animal tissue to more efficiently natural surfactant.Several years
The preceding U.S. uses Tel Aviv, Israel university professor and initiates invention, by the completely new emulsifier system extracted in marine organisms
Business cosmetics made of chemical emulsifier are not had at world's the first, lotion is fine and smooth, smooth, is popular.
For the administration of health for reinforcing cosmetics industrial enterprise, ensure cosmetics health quality and consumer using safe,
And cosmetics industry develops more perfect, more creates perfect product and benefits the people, our raw materials to cosmetics
And production technology will strict control, and have certain standard requirements.
With the influence of development and the accession to WTO of global economic integration, the raising of living standards of the people, China's makeup
Product market is just entering the flourishing as never before phase, and market competition is extremely fierce.
Stoste in cosmetic industry refers to adding relatively single high concentration skin care ingredient, can be directed to various fleshes
Skin needs, maintenance more direct to skin, safer, more potent, and the beauty for allowing skin to restore optimum state in a short time produces
Product.
The effect of stoste, has specific aim, and different stoste can improve skin for different skin problems, highly concentrated
Degree ingredient bring skin directly, effective maintenance, as aloe stoste has moisturizing, releive skin the effect of;Snail stoste repairing
The skin flaw such as acne scar brings skin new life to experience comprehensively there are also the multi-efficiencies such as microgroove are desalinated;Collagen stoste can be promoted
Elastic force enables skin consolidation full.
The effect of stoste, has the advantages that specific aim this this is both and the determination of stoste, although good for effect, function
Can be excessively single, although stoste can be compounded with various skin care item and bottom cosmetic, between different types of skin care item,
It is therefore, to be badly in need of a kind of stoste that can have a variety of skin effects in the presence of the possible of side effect is generated.
Summary of the invention
The purpose of the present invention is to provide a kind of stostes with a variety of skin effects, to solve to mention in above-mentioned background technique
Out the problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows: water:
80.05445%, Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3
Propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol fourth
Ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:
1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%.
Further, with the stoste of a variety of skin effects, by weight percentage, specific formula component is as follows: water:
80.05445%, Genapol G-260:2%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3
Propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol fourth
Ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:
1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%.
Further, with the stoste of a variety of skin effects, by weight percentage, specific formula component is as follows: water:
79.05445%, Genapol G-260:2%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3
Propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol fourth
Ether: 1%, CO40:2.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:
1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%.
Further, the water in the present invention is deionized water;If using tap water, because containing Ca2+, Mg2+ ion,
Under alkaline condition, the oxyhydroxide of calcium, magnesium is generated, is a kind of cotton-shaped cohesion suspended matter, it is past when being put into emulsification agitated kettle
Toward the screen cloth for blocking piping filter, dilute light buck is caused to be unable to Channel Group.
Further, the evaporation when consideration in the present invention is heated to ionized water and in whipping process, aggregate losses are about
2%-3% often additionally adds 2%-3% moisture to accomplish stoste recovery rate 100%, supplements the loss of water.
A kind of preparation method of the stoste with a variety of skin effects, comprising the following steps:
S1, water phase preparation:
By Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3
Propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, hydrolyze silkworm
Silk: 0.2%, it is added in the deionized water of part, water is heated to 90-95 DEG C in a stainless steel jacket water (J.W.) steam heating boiler, dimension
20min sterilizing is held, heating kettle is equipped with simple turbine stirrer, and raw material is made to accelerate dissolution, accelerates heat transfer, so that water is heated up, be heated to
90 DEG C of water phase is cooled to 72-75 DEG C, and to obtain A water phase stand-by;Long-time heating should be avoided, in order to avoid cause viscosity change, for supplement
The moisture vapored away when heating and emulsification can be added 2% water by formula;
The preparation of S2, oily phase:
By vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%,
Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, De Minshu: 0.1%, sunset
It is yellow: 0.00015%, burnt sugar coloring: 0.0054%;Be added collet dissolving pan in, open steam heating, under constant agitation plus
Heat makes it sufficiently melt or be uniformly dissolved to obtain oily mutually stand-by to 70-75 DEG C;Avoid excessively heat and long-time heating with
Prevent material composition oxidation deterioration;
S3, emulsification:
A water phase being slowly added into oily phase, while homogenizer, after water adds, homogeneous blender is stirred for 5 minutes,
Then be added through ultraviolet disinfection and not heated another part deionized water (water of the part is B water phase, B water phase+A water
Phase=whole deionized water);The weight of B water phase can be measured in sunset phase pot or with metering pump-metered;
S4, cooling:
The cooling procedure of emulsion is realized by the stirring of scraper plate blender and the reflux of collet cooling water, and 1000L emulsification is stirred
The scraper plate blender revolving speed 20-30r/min for mixing pot can generate many bubbles, slowly when homogeneous blender starts emulsification stirring
The purpose of stirring is that the bubble risen is made gradually to disappear.
Further, the ratio of the A phase water in the present invention and B phase water: A=0.2-0.3, B phase=0.7-0.8.
Further, stirring is stronger when emulsification, and emulsifier can be lower, but emulsified body granular size and stirring are strong
Degree and emulsifier have relationship, and the present invention is advantageous to emulsifying using higher speed stirring when starting emulsification, terminate in emulsification
And after entering cooling stage, then it with medium speed or mixes slowly advantageous, stirs always to room temperature, can reduce be mixed into gas in this way
Bubble.
Compared with prior art, the beneficial effects of the present invention are: volunteer of the embodiment of the present invention indicates original of the invention
Liquid good penetrability easily absorbs, and clearly not sticky using rear face, whitening, moistening effect are good, promotes skin metabolism, and long
Moisturizing is imitated, keeps skin water profit smooth, it is flexible;There is allergic phenomena in non-someone in whole subjects simultaneously, does not also occur skin
The situations such as skin convulsion itches, shouting pain, redness, therefore, the mild safety of the present invention can be used for a long time.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment one, a kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows:
Water: 80.05445%,
Genapol G-260:3%,
Carbopol Ultrez U21:0.05%,
SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 3%,
Decoyl ketone: 0.5%,
Propylene glycol: 4%,
Phenoxyethanol: 0.3%,
TEA triethanolamine: 0.05%,
Vanillyl alcohol butyl ether: 1%,
CO40:1.5%,
Grapefruit essential oil: 0.04%,
AQUAXYL:1%,
Liporeductl:1.5%,
HYDROVANCE:1%,
Caffeine silanol C:2%,
BN:0.5%,
Hydrolysis silk: 0.2%,
De Minshu: 0.1%,
Sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%;
Embodiment two, a kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows:
Water: 80.05445%,
Genapol G-260:2%,
Carbopol Ultrez U21:0.05%,
SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 4%,
Decoyl ketone: 0.5%,
Propylene glycol: 4%,
Phenoxyethanol: 0.3%,
TEA triethanolamine: 0.05%,
Vanillyl alcohol butyl ether: 1%,
CO40:1.5%,
Grapefruit essential oil: 0.04%,
AQUAXYL:1%,
Liporeductl:1.5%,
HYDROVANCE:1%,
Caffeine silanol C:2%,
BN:0.5%,
Hydrolysis silk: 0.2%,
De Minshu: 0.1%,
Sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%;
Embodiment three, a kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows:
Water: 79.05445%,
Genapol G-260:2%,
Carbopol Ultrez U21:0.05%,
SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 4%,
Decoyl ketone: 0.5%,
Propylene glycol: 4%,
Phenoxyethanol: 0.3%,
TEA triethanolamine: 0.05%,
Vanillyl alcohol butyl ether: 1%,
CO40:2.5%,
Grapefruit essential oil: 0.04%,
AQUAXYL:1%,
Liporeductl:1.5%,
HYDROVANCE:1%,
Caffeine silanol C:2%,
BN:0.5%,
Hydrolysis silk: 0.2%,
De Minshu: 0.1%,
Sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%;
Water in the present invention is deionized water;If using tap water, because containing Ca2+, Mg2+ ion, in alkaline condition
Under, the oxyhydroxide of calcium, magnesium is generated, is that a kind of cotton-shaped cohesion suspended matter often blocks pipe when being put into emulsification agitated kettle
The screen cloth of road filter causes dilute light buck to be unable to Channel Group.
Evaporation when consideration in the present invention is heated to ionized water and in whipping process, aggregate losses about 2%-3%, to do
To stoste recovery rate 100%, often additionally add 2%-3% moisture, supplements the loss of water.
The entitled glycerin polyether -26 of INCI of Genapol G260 in the present invention;It is the glycerol of 26 moles of oxireme
Addition product has smooth, fine and smooth sense of touch as moisturizer and lubricant, it can be used as skin conditioning agent use, with sun
Ion, nonionic and anionic surfactant have good compatibility, and stablize within the scope of extensive PH.
It is a kind of hydrophobically modified, crosslinking acrylate copolymer by Carbopol Ultrez U21 in the present invention, can
Thickening, stabilization and suspension characteristic are brought for all kinds of personal care products;It buys from Lu Borun Lubrizol company.
The entitled polyacrylate cross-linked polymer -6 of the INCI of SEPIMAX ZEN in the present invention;With very high
The polyelectrolyte polymers of association can utmostly resist electrolyte and destroy to formula bring, while have well
Suspending stabilized ability is suitble to the various formulas such as the transparent system containing particle, superflow and white shape gel.
CO40 Chinese name in the present invention: rilanit special is a kind of good solubilizer and emulsifier, can make for days
So and chemically synthesized organic oil-soluble ingredients dissolve the property and smell for forming stablizing solution, and not changing substance in water,
Improve product and function, performance and sense organ.In Cosmetic Manufacture manufacturing field especially in opaque products, CO40 has it solely
Special attraction, it can reduce or eliminate the organic solvent in product, cheap water instead of, not only safety but also reduce organic
The detrimental effect of solvent and influence, while making that the fragrance of product is purer, feels more natural.
TEA in the present invention is triethanolamine TEOA also known as TEOA, TEA;Alias: 2,2,2- hydroxyl triethylamines, three hydroxyl second
Base amine, chemical formula (molecular formula): C6H15O3N is a kind of colourless to light yellow thick liquid for having ammonia taste, soluble easily in water, second
Alcohol, in alkalinity, aqueous ph value about 10.5 is a kind of widely used industrial chemicals, is used as daily chemical product wetting agent etc..
The entitled Xylitol-based glucoside of the INCI of AQUAXYL in the present invention (and) anhydro xylitol (and) xylitol,
Properties of product and application;The active constituent of natural botanical source, can moisturizing and rebuild skin texture system, promote GAGs (thoroughly
Bright matter acid and chondroitin sulfate) content increase, improves the moisture content of epidermis and corium, promotes ceramide synthesis, reinforce skin
Skin barrier action improves skin texture, reduces water loss, can be used in various moisturizing formulas, has the function of anti-aging;
Liporeductl in the present invention is a kind of nanometer of weight-reducing mixture, it can reduce and prevent Adipogenesis, and
Fat-reducing effect is provided, which can be included into body care formula, especially in anti-cellulite and diet products;Purchase is certainly
LIPOTEC company.
The entitled ethoxy urea of the INCI of HYDROVANCE in the present invention;Properties of product and application: ethoxy urea can
Fabulous moistening effect is provided, the elasticity of skin is increased, improves the skin sense of formula;It can also enter hair by epidermis, repair
Multiple internal sliver, therefore hair can be soaked and enhance hair quality.
The entitled siloxanes triol alginate esters/caffeine of the INCI of caffeine silanol C in the present invention, properties of product and
Using: silanol and caffeine synergistic effect have solution rouge function outstanding.Cyclic annular adenosine phosphoric acid activation is promoted by element silicon
Rouge is solved, the formation and accumulation of triglycerides are reduced by the inhibiting effect to lipoprotein lipase, while rebuilding skin histology, reaches tight
Skin, anti-inflammatory and other effects.Suitable for weight reducing, body and skin of face consolidation remove the products such as eye pouch.
BN full name in the present invention isELITE BN;The entitled starch ocentyl succinic aluminium of an INCI/nitrogen
Change boron;Properties of product and application: skin sense modifying agent combines boron nitride powder on the basis of DRY-FLO PC improves skin sense
Good characteristics.The sliding sense of fabulous children and coverage effect are imparted, also there is better adhesiveness compared to DRY-FLO PC starch.
De Minshu full name in the present invention are as follows:De Minshu 143535;INCI title are as follows: Butylene
Glycol, Pentylene Glycol, Hydroxyphenyl Propamidobenzoic Acid butanediol, 1,2- pentanediol,
Hydroxyphenyl propyl amides benzoic acid;Properties of product and application: there is antihistamine, anti-irritant, the itching-relieving action (scabies as caused by dry
Itch, the nursing of skin after the elderly's pruitus and bite by mosquitos);Effectively inhibit erythema, itch and mistake caused by histamine
Quick reaction;It is good with other material combinations.
Sunset yellow and burnt sugar coloring in the present invention are colorant.
A kind of preparation method of the stoste with a variety of skin effects, comprising the following steps:
S1, water phase preparation:
By Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3
Propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, hydrolyze silkworm
Silk: 0.2%, it is added in the deionized water of part, water is heated to 90-95 DEG C in a stainless steel jacket water (J.W.) steam heating boiler, dimension
20min sterilizing is held, heating kettle is equipped with simple turbine stirrer, and raw material is made to accelerate dissolution, accelerates heat transfer, so that water is heated up, be heated to
90 DEG C of water phase is cooled to 72-75 DEG C, and to obtain A water phase stand-by;Long-time heating should be avoided, in order to avoid cause viscosity change, for supplement
The moisture vapored away when heating and emulsification can be added 2% water by formula;
The preparation of S2, oily phase:
By vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%,
Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, De Minshu: 0.1%, sunset
It is yellow: 0.00015%, burnt sugar coloring: 0.0054%;Be added collet dissolving pan in, open steam heating, under constant agitation plus
Heat makes it sufficiently melt or be uniformly dissolved to obtain oily mutually stand-by to 70-75 DEG C;Avoid excessively heat and long-time heating with
Prevent material composition oxidation deterioration;
S3, emulsification:
A water phase being slowly added into oily phase, while homogenizer, after water adds, homogeneous blender is stirred for 5 minutes,
Then be added through ultraviolet disinfection and not heated another part deionized water (water of the part is B water phase, B water phase+A water
Phase=whole deionized water);The weight of B water phase can be measured in sunset phase pot or with metering pump-metered;
S4, cooling:
The cooling procedure of emulsion is realized by the stirring of scraper plate blender and the reflux of collet cooling water, using centrifugal pump-
Cooling tower forced circulation reflux type effect is good;
The revolving speed of scraper plate blender is as slow as possible, and 1000L emulsifies the scraper plate blender revolving speed 20-30r/min of agitated kettle,
When homogeneous blender starts emulsification stirring, many bubbles can be generated, the purpose being slowly stirred is that the bubble risen is made gradually to disappear
It loses.
Further, the ratio (see the table below -1) of the A phase water in the present invention and B phase water has to selection suitably, generally, low
The condensed emulsified cognition of viscosity makes the addition of next step B phase water be easy to carry out.
The ratio of table -1 A phase and B phase water
Currently preferred that A phase is compressed to lower value, A=0.2-0.3, B phase can be improved to 0.7-0.8.
Further, stirring is stronger when emulsification, and emulsifier can be lower, but emulsified body granular size and stirring are strong
Degree and emulsifier have relationship, and universal law is as shown in table -2.
The relationship of -2 stirring intensity of table and granular size and emulsifier
Stirring intensity | Granular size | Emulsifier |
Difference (craft or paddle stirring) | Greatly (emulsification is poor) | On a small quantity |
Difference | It is medium | Middle amount |
(colloid mill) by force | It is medium | Amount in as little as |
(homogenizer) by force | It is small | Amount in as little as |
Medium (craft or rotary propeller type) | It is small | In to a large amount |
Difference | It is superfine (clear) | Very high amount |
Excessive strong stirring might not be effective to reduction granular size, and is easily mixed into air, using medium
When stirring intensity, with the available thin particle of phase inversion method, when being stirred using paddle or rotary propeller type, it should be noted that do not make air
It stirs into emulsified body.
Ordinary circumstance is, advantageous to emulsifying using higher speed stirring when starting emulsification, terminates in emulsification and enters cooling
After stage, then with medium speed or mixes slowly advantageous, stir always to room temperature, can reduce be mixed into bubble in this way.
Properties of product test:
1. the Detection of Stability of product
When studying and the stability of emulsified body system being discussed, there is famous Stokes (Stokes) equation:
V=2rr (p2-p1) × g/9 η
In formula: the sinking speed of particle (drop) in v- system
Medium viscosity in η-system
The radius (2 powers that the rr in this formula represents r) of particle (drop) in r- system
G- acceleration of gravity,
P1, p2 are respectively interior phase, the density of foreign minister.
Sinking speed v in formula is exactly the aggregation velocity of the particle (drop) in system, it is clear that if aggregation velocity η is big,
The interior phase (oil mutually or water phase) of system is just easily accumulated on causes water-oil separating and unstable together, so, sinking speed
Smaller, cream or emulsion system are just more stable;By formula it follows that working as interior phase and the foreign minister of system, i.e., oily phase and water phase
Density difference (p2-p1) is cured hour, and system is more stable;When the particle (drop) of system is smaller, i.e., v is smaller, that is, oil droplet or water
Drop is dispersed thinner, and v is just smaller, and system is more stable.So efficient emulsifying device, revolving speed should be made when preparing emulsified body
There is a 3000rpm or more, the dispersion degree of system is high, and the stability of product is good and the glossy exquisiteness of appearance;But in formula system is situated between
The viscosity of matter (i.e. foreign minister), sinking speed v are inversely proportional with η, i.e. the viscosity η of foreign minister is bigger, and v is smaller, and system is just more stable.Such as
When preparing O/W type cream, it can be thickened by the way that hydrophilic macromolecular compounds are added in foreign minister (water phase) to improve the stabilization of cream
Property.
For the stability for guaranteeing cosmetic product, design and experimental stage in formula can also strengthen sample
Stability test, to judge its stability.
Method specifically: determine certain time interval (6h or for 24 hours, preferably for 24 hours), product is first stirred into high temperature (50
DEG C) in insulating box, taken out after the time of above-mentioned determination, restore room temperature, then (- 15 DEG C) are stirred into refrigerator, and pass through same
Time, take out restore room temperature after, place into high-temperature incubator, so after recycling twice or thrice, observe product
Stability shows that the formula design of the embodiment one of the product is the most reasonable, and the stability of each embodiment is as shown in following table -3.
The stability of each embodiment of table -3
Embodiment | Embodiment one | Embodiment two | Embodiment three |
Stability | It is the most stable | Stablize | Difference |
Wherein the stability of the product of embodiment 1 is best, is not any change, and occurs a small amount of sink in the product of embodiment two
Then there is lamination slightly in starch, the product of embodiment three.
2. the hygienic chemistry index of product: " cosmetics safety technical specification " (version in 2015) Physico-chemical tests method is referred to,
As a result as shown in table -4.
- 4 hygienic chemistry testing result of table
Inspection project | Embodiment one | Embodiment two | Embodiment three |
Arsenic | ≤0.1mg/kg | ≤0.1mg/kg | ≤0.1mg/kg |
Mercury | ≤0.2mg/kg | ≤0.2mg/kg | ≤0.2mg/kg |
Lead | ≤10mg/kg | ≤10mg/kg | ≤10mg/kg |
Methanol | ≤5mg/kg | ≤5mg/kg | ≤5mg/kg |
3. the microbiological indicator of product: " cosmetics safety technical specification " (version in 2015) microorganism detection method is referred to,
As a result as shown in table -5.
- 5 microorganism detection result of table
Inspection project | Embodiment one | Embodiment two | Embodiment three |
Total plate count | ≤1000CFU/g | ≤1000CFU/g | ≤1000CFU/g |
Yeast and mold sum | ≤10CFU/g | ≤50CFU/g | ≤100CFU/g |
Thermotolerant coliform | It does not detect | It does not detect | It does not detect |
Staphylococcus aureus | It does not detect | It does not detect | It does not detect |
4. the performance test of product: selection volunteer 18, the age 25-30 years old, average age 28 years old;Volunteer is divided equally
At 6 people in 3 groups, every group, 1-2 group is experimental group, and third group is control group, and corresponding volunteer is corresponding to use embodiment 1-3
Stoste;4th group of volunteer does not use any cosmetics;Continuous experiment 50 days, volunteer was used before and after cosmetics in every 10 days
It compares.As a result as shown in table -6.
The performance test results of -6 product of table
Note: it because the skin quality of different users is different, tells in same test group more than half people, and default the group to make
(such as the 10th day four volunteer's microgrooves in first group significantly reduce, skin shine improves, that is, default the group with effective
Effect is that microgroove significantly reduces, skin shine improves), while all test groups are without any adverse reactions.
Volunteer of the embodiment of the present invention indicates stoste good penetrability of the invention, easily absorbs, clearly not using rear face
Sticky, whitening, moistening effect are good, promote skin metabolism, and long-acting moisturizing, keep skin water profit smooth, flexible;
Wherein the stoste of the stability highest preferred embodiment 1 of embodiment 1 is preferred embodiment;
There is allergic phenomena in non-someone in whole subjects simultaneously, do not occur yet skin convulsion itch, shouting pain, the shapes such as redness
Condition.Therefore, the present invention is mildly safe, can be used for a long time.
The preferred embodiment of the patent is described in detail above, but this patent is not limited to above-mentioned embodiment party
Formula within the knowledge of one of ordinary skill in the art can also be under the premise of not departing from this patent objective
It makes a variety of changes.
Claims (8)
1. a kind of stoste with a variety of skin effects, which is characterized in that by weight percentage, specific formula component is as follows:
Water: 80.05445%, Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanilla
Alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%,
HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow:
0.00015%, burnt sugar coloring: 0.0054%.
2. the stoste according to claim 1 with a variety of skin effects, which is characterized in that with a variety of skin effects
Stoste, by weight percentage, specific formula component are as follows: water: 80.05445%, Genapol G-260:2%, Carbopol
Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, benzene
Oxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%,
AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, hydrolysis
Silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, burnt sugar coloring: 0.0054%.
3. the stoste according to claim 1 with a variety of skin effects, which is characterized in that with a variety of skin effects
Stoste, by weight percentage, specific formula component are as follows: water: 79.05445%, Genapol G-260:2%, Carbopol
Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, benzene
Oxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol butyl ether: 1%, CO40:2.5%, grapefruit essential oil: 0.04%,
AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, hydrolysis
Silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, burnt sugar coloring: 0.0054%.
4. the stoste according to claim 1 with a variety of skin effects, which is characterized in that the present invention in water be go from
Sub- water;If, because containing Ca2+, Mg2+ ion, under alkaline condition, generating the oxyhydroxide of calcium, magnesium using tap water, being
A kind of cotton-shaped cohesion suspended matter often blocks the screen cloth of piping filter, causes dilute light buck when being put into emulsification agitated kettle
It is unable to Channel Group.
5. the stoste according to claim 1 with a variety of skin effects, which is characterized in that the present invention in consideration to from
Evaporation when sub- water heats and in whipping process, aggregate losses about 2%-3%, to accomplish stoste recovery rate 100%, often additionally
Add 2%-3% moisture, supplements the loss of water.
6. a kind of preparation method of the stoste with a variety of skin effects, which comprises the following steps:
S1, water phase preparation:
By Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 the third two
Alcohol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, hydrolyze silk:
0.2%, it is added in the deionized water of part, water is heated to 90-95 DEG C in a stainless steel jacket water (J.W.) steam heating boiler, maintains
20min sterilizing, heating kettle are equipped with simple turbine stirrer, and raw material is made to accelerate dissolution, accelerate heat transfer, so that water is heated up, be heated to 90
DEG C water phase be cooled to 72-75 DEG C to obtain A water phase stand-by;Long-time heating should be avoided, in order to avoid causing viscosity change, add for supplement
The moisture vapored away when heat and emulsification can be added 2% water by formula;
The preparation of S2, oily phase:
By vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:
1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, De Minshu: 0.1%, sunset yellow:
0.00015%, burnt sugar coloring: 0.0054%;It is added in collet dissolving pan, opens steam heating, heat under constant agitation
To 70-75 DEG C, it is made sufficiently to melt or be uniformly dissolved to obtain oily mutually stand-by;Avoid excessively heat and long-time heating to prevent
Only material composition oxidation deterioration;
S3, emulsification:
A water phase is slowly added into oily phase, while homogenizer, after water adds, homogeneous blender is stirred for 5 minutes, then
Be added another part deionized water not heated through ultraviolet disinfection (water of the part is B water phase, B water phase+A water phase=
Whole deionized water);The weight of B water phase can be measured in sunset phase pot or with metering pump-metered;
S4, cooling:
The cooling procedure of emulsion is to realize that 1000L emulsifies agitated kettle by the stirring of scraper plate blender and the reflux of collet cooling water
Scraper plate blender revolving speed 20-30r/min, homogeneous blender start emulsification stirring when, many bubbles can be generated, be slowly stirred
Purpose be make rise bubble gradually disappear.
7. the preparation method of the stoste according to claim 6 with a variety of skin effects, which is characterized in that in the present invention
A phase water and B phase water ratio: A=0.2-0.3, B phase=0.7-0.8.
8. the preparation method of the stoste according to claim 6 with a variety of skin effects, which is characterized in that stirred when emulsification
It mixes more strongly, emulsifier can be lower, but emulsified body granular size and stirring intensity and emulsifier have relationship, this
Invention is advantageous to emulsifying using higher speed stirring when starting to emulsify, after emulsification end enters cooling stage, then with medium
Speed mixes slowly favorably, stirs always to room temperature, can reduce be mixed into bubble in this way.
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CN115590772A (en) * | 2022-10-31 | 2023-01-13 | 北京茂思商贸有限公司(Cn) | Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof |
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CN107233282A (en) * | 2017-06-20 | 2017-10-10 | 诺斯贝尔化妆品股份有限公司 | A kind of collagen, which compacts, lifts plentiful shining color face cream |
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2018
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CN107233282A (en) * | 2017-06-20 | 2017-10-10 | 诺斯贝尔化妆品股份有限公司 | A kind of collagen, which compacts, lifts plentiful shining color face cream |
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CN115590772A (en) * | 2022-10-31 | 2023-01-13 | 北京茂思商贸有限公司(Cn) | Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof |
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