CN109498509A - A kind of stoste and preparation method thereof with a variety of skin effects - Google Patents

A kind of stoste and preparation method thereof with a variety of skin effects Download PDF

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CN109498509A
CN109498509A CN201811419104.0A CN201811419104A CN109498509A CN 109498509 A CN109498509 A CN 109498509A CN 201811419104 A CN201811419104 A CN 201811419104A CN 109498509 A CN109498509 A CN 109498509A
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water
stoste
phase
variety
skin
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张庆
孔令超
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/733Alginic acid; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/49Solubiliser, Solubilising system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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Abstract

The stoste and preparation method thereof with a variety of skin effects that the invention discloses a kind of, by weight percentage, specific formula component is as follows: water, Carbopol Ultrez U21, SEPIMAX ZEN, 1,3 propylene glycol, decoyl ketone, propylene glycol, Phenoxyethanol, TEA triethanolamine, vanillyl alcohol butyl ether, CO40, grapefruit essential oil, AQUAXYL, Liporeductl, HYDROVANCE, caffeine silanol, BN hydrolyze silk, De Minshu, sunset yellow, burnt sugar coloring;Stoste good penetrability of the invention easily absorbs, and clearly not sticky using rear face, whitening, moistening effect are good, promotes skin metabolism, and long-acting moisturizing, keeps skin water profit smooth, flexible;There is allergic phenomena in non-someone in whole subjects simultaneously, do not occur yet skin convulsion itch, shouting pain, the situations such as redness, therefore, the mild safety of the present invention can be used for a long time.

Description

A kind of stoste and preparation method thereof with a variety of skin effects
Technical field
The present invention relates to Cosmetic Manufacture field, specifically a kind of stoste and its preparation side with a variety of skin effects Method.
Background technique
" loving beauty is part of human nature " since having human civilization by oneself, has just there is the pursuit to beautification itself.In original society Meeting, in sacrifice rites, animal fat can be smeared makes the colour of skin of oneself seem health and have light on the skin for some clans Pool, this also earliest skin care behavior at last.It can be seen that the history of cosmetics can almost calculate that the presence from the mankind is opened Begin.
Skin protection cosmetics is mainly to be formed by emulsifier by homogenization by this incompatible oil (phase) with water (phase), But the emulsifier in traditional cosmetics is all compound, including various surfactants are all chemical synthesis, this was not both inconsistent The psychological tendency to go back to nature is closed, does not also meet environmental requirement, and bring the stimulation to skin.In recent years, people are big The lecithin and Tea Saponin extracted in soya-bean oil and plant of theaceae seed is used as emulsifier production cosmetics and obtains certain effect Fruit, this is referred to as natural surfactant, is also can extract from animal tissue to more efficiently natural surfactant.Several years The preceding U.S. uses Tel Aviv, Israel university professor and initiates invention, by the completely new emulsifier system extracted in marine organisms Business cosmetics made of chemical emulsifier are not had at world's the first, lotion is fine and smooth, smooth, is popular.
For the administration of health for reinforcing cosmetics industrial enterprise, ensure cosmetics health quality and consumer using safe, And cosmetics industry develops more perfect, more creates perfect product and benefits the people, our raw materials to cosmetics And production technology will strict control, and have certain standard requirements.
With the influence of development and the accession to WTO of global economic integration, the raising of living standards of the people, China's makeup Product market is just entering the flourishing as never before phase, and market competition is extremely fierce.
Stoste in cosmetic industry refers to adding relatively single high concentration skin care ingredient, can be directed to various fleshes Skin needs, maintenance more direct to skin, safer, more potent, and the beauty for allowing skin to restore optimum state in a short time produces Product.
The effect of stoste, has specific aim, and different stoste can improve skin for different skin problems, highly concentrated Degree ingredient bring skin directly, effective maintenance, as aloe stoste has moisturizing, releive skin the effect of;Snail stoste repairing The skin flaw such as acne scar brings skin new life to experience comprehensively there are also the multi-efficiencies such as microgroove are desalinated;Collagen stoste can be promoted Elastic force enables skin consolidation full.
The effect of stoste, has the advantages that specific aim this this is both and the determination of stoste, although good for effect, function Can be excessively single, although stoste can be compounded with various skin care item and bottom cosmetic, between different types of skin care item, It is therefore, to be badly in need of a kind of stoste that can have a variety of skin effects in the presence of the possible of side effect is generated.
Summary of the invention
The purpose of the present invention is to provide a kind of stostes with a variety of skin effects, to solve to mention in above-mentioned background technique Out the problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows: water: 80.05445%, Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 Propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol fourth Ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE: 1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, Burnt sugar coloring: 0.0054%.
Further, with the stoste of a variety of skin effects, by weight percentage, specific formula component is as follows: water: 80.05445%, Genapol G-260:2%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 Propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol fourth Ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE: 1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, Burnt sugar coloring: 0.0054%.
Further, with the stoste of a variety of skin effects, by weight percentage, specific formula component is as follows: water: 79.05445%, Genapol G-260:2%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 Propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol fourth Ether: 1%, CO40:2.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE: 1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, Burnt sugar coloring: 0.0054%.
Further, the water in the present invention is deionized water;If using tap water, because containing Ca2+, Mg2+ ion, Under alkaline condition, the oxyhydroxide of calcium, magnesium is generated, is a kind of cotton-shaped cohesion suspended matter, it is past when being put into emulsification agitated kettle Toward the screen cloth for blocking piping filter, dilute light buck is caused to be unable to Channel Group.
Further, the evaporation when consideration in the present invention is heated to ionized water and in whipping process, aggregate losses are about 2%-3% often additionally adds 2%-3% moisture to accomplish stoste recovery rate 100%, supplements the loss of water.
A kind of preparation method of the stoste with a variety of skin effects, comprising the following steps:
S1, water phase preparation:
By Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 Propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, hydrolyze silkworm Silk: 0.2%, it is added in the deionized water of part, water is heated to 90-95 DEG C in a stainless steel jacket water (J.W.) steam heating boiler, dimension 20min sterilizing is held, heating kettle is equipped with simple turbine stirrer, and raw material is made to accelerate dissolution, accelerates heat transfer, so that water is heated up, be heated to 90 DEG C of water phase is cooled to 72-75 DEG C, and to obtain A water phase stand-by;Long-time heating should be avoided, in order to avoid cause viscosity change, for supplement The moisture vapored away when heating and emulsification can be added 2% water by formula;
The preparation of S2, oily phase:
By vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, De Minshu: 0.1%, sunset It is yellow: 0.00015%, burnt sugar coloring: 0.0054%;Be added collet dissolving pan in, open steam heating, under constant agitation plus Heat makes it sufficiently melt or be uniformly dissolved to obtain oily mutually stand-by to 70-75 DEG C;Avoid excessively heat and long-time heating with Prevent material composition oxidation deterioration;
S3, emulsification:
A water phase being slowly added into oily phase, while homogenizer, after water adds, homogeneous blender is stirred for 5 minutes, Then be added through ultraviolet disinfection and not heated another part deionized water (water of the part is B water phase, B water phase+A water Phase=whole deionized water);The weight of B water phase can be measured in sunset phase pot or with metering pump-metered;
S4, cooling:
The cooling procedure of emulsion is realized by the stirring of scraper plate blender and the reflux of collet cooling water, and 1000L emulsification is stirred The scraper plate blender revolving speed 20-30r/min for mixing pot can generate many bubbles, slowly when homogeneous blender starts emulsification stirring The purpose of stirring is that the bubble risen is made gradually to disappear.
Further, the ratio of the A phase water in the present invention and B phase water: A=0.2-0.3, B phase=0.7-0.8.
Further, stirring is stronger when emulsification, and emulsifier can be lower, but emulsified body granular size and stirring are strong Degree and emulsifier have relationship, and the present invention is advantageous to emulsifying using higher speed stirring when starting emulsification, terminate in emulsification And after entering cooling stage, then it with medium speed or mixes slowly advantageous, stirs always to room temperature, can reduce be mixed into gas in this way Bubble.
Compared with prior art, the beneficial effects of the present invention are: volunteer of the embodiment of the present invention indicates original of the invention Liquid good penetrability easily absorbs, and clearly not sticky using rear face, whitening, moistening effect are good, promotes skin metabolism, and long Moisturizing is imitated, keeps skin water profit smooth, it is flexible;There is allergic phenomena in non-someone in whole subjects simultaneously, does not also occur skin The situations such as skin convulsion itches, shouting pain, redness, therefore, the mild safety of the present invention can be used for a long time.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment one, a kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows:
Water: 80.05445%,
Genapol G-260:3%,
Carbopol Ultrez U21:0.05%,
SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 3%,
Decoyl ketone: 0.5%,
Propylene glycol: 4%,
Phenoxyethanol: 0.3%,
TEA triethanolamine: 0.05%,
Vanillyl alcohol butyl ether: 1%,
CO40:1.5%,
Grapefruit essential oil: 0.04%,
AQUAXYL:1%,
Liporeductl:1.5%,
HYDROVANCE:1%,
Caffeine silanol C:2%,
BN:0.5%,
Hydrolysis silk: 0.2%,
De Minshu: 0.1%,
Sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%;
Embodiment two, a kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows:
Water: 80.05445%,
Genapol G-260:2%,
Carbopol Ultrez U21:0.05%,
SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 4%,
Decoyl ketone: 0.5%,
Propylene glycol: 4%,
Phenoxyethanol: 0.3%,
TEA triethanolamine: 0.05%,
Vanillyl alcohol butyl ether: 1%,
CO40:1.5%,
Grapefruit essential oil: 0.04%,
AQUAXYL:1%,
Liporeductl:1.5%,
HYDROVANCE:1%,
Caffeine silanol C:2%,
BN:0.5%,
Hydrolysis silk: 0.2%,
De Minshu: 0.1%,
Sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%;
Embodiment three, a kind of stoste with a variety of skin effects, by weight percentage, specific formula component is as follows:
Water: 79.05445%,
Genapol G-260:2%,
Carbopol Ultrez U21:0.05%,
SEPIMAX ZEN:0.2%,
1,3 propylene glycol: 4%,
Decoyl ketone: 0.5%,
Propylene glycol: 4%,
Phenoxyethanol: 0.3%,
TEA triethanolamine: 0.05%,
Vanillyl alcohol butyl ether: 1%,
CO40:2.5%,
Grapefruit essential oil: 0.04%,
AQUAXYL:1%,
Liporeductl:1.5%,
HYDROVANCE:1%,
Caffeine silanol C:2%,
BN:0.5%,
Hydrolysis silk: 0.2%,
De Minshu: 0.1%,
Sunset yellow: 0.00015%,
Burnt sugar coloring: 0.0054%;
Water in the present invention is deionized water;If using tap water, because containing Ca2+, Mg2+ ion, in alkaline condition Under, the oxyhydroxide of calcium, magnesium is generated, is that a kind of cotton-shaped cohesion suspended matter often blocks pipe when being put into emulsification agitated kettle The screen cloth of road filter causes dilute light buck to be unable to Channel Group.
Evaporation when consideration in the present invention is heated to ionized water and in whipping process, aggregate losses about 2%-3%, to do To stoste recovery rate 100%, often additionally add 2%-3% moisture, supplements the loss of water.
The entitled glycerin polyether -26 of INCI of Genapol G260 in the present invention;It is the glycerol of 26 moles of oxireme Addition product has smooth, fine and smooth sense of touch as moisturizer and lubricant, it can be used as skin conditioning agent use, with sun Ion, nonionic and anionic surfactant have good compatibility, and stablize within the scope of extensive PH.
It is a kind of hydrophobically modified, crosslinking acrylate copolymer by Carbopol Ultrez U21 in the present invention, can Thickening, stabilization and suspension characteristic are brought for all kinds of personal care products;It buys from Lu Borun Lubrizol company.
The entitled polyacrylate cross-linked polymer -6 of the INCI of SEPIMAX ZEN in the present invention;With very high The polyelectrolyte polymers of association can utmostly resist electrolyte and destroy to formula bring, while have well Suspending stabilized ability is suitble to the various formulas such as the transparent system containing particle, superflow and white shape gel.
CO40 Chinese name in the present invention: rilanit special is a kind of good solubilizer and emulsifier, can make for days So and chemically synthesized organic oil-soluble ingredients dissolve the property and smell for forming stablizing solution, and not changing substance in water, Improve product and function, performance and sense organ.In Cosmetic Manufacture manufacturing field especially in opaque products, CO40 has it solely Special attraction, it can reduce or eliminate the organic solvent in product, cheap water instead of, not only safety but also reduce organic The detrimental effect of solvent and influence, while making that the fragrance of product is purer, feels more natural.
TEA in the present invention is triethanolamine TEOA also known as TEOA, TEA;Alias: 2,2,2- hydroxyl triethylamines, three hydroxyl second Base amine, chemical formula (molecular formula): C6H15O3N is a kind of colourless to light yellow thick liquid for having ammonia taste, soluble easily in water, second Alcohol, in alkalinity, aqueous ph value about 10.5 is a kind of widely used industrial chemicals, is used as daily chemical product wetting agent etc..
The entitled Xylitol-based glucoside of the INCI of AQUAXYL in the present invention (and) anhydro xylitol (and) xylitol, Properties of product and application;The active constituent of natural botanical source, can moisturizing and rebuild skin texture system, promote GAGs (thoroughly Bright matter acid and chondroitin sulfate) content increase, improves the moisture content of epidermis and corium, promotes ceramide synthesis, reinforce skin Skin barrier action improves skin texture, reduces water loss, can be used in various moisturizing formulas, has the function of anti-aging;
Liporeductl in the present invention is a kind of nanometer of weight-reducing mixture, it can reduce and prevent Adipogenesis, and Fat-reducing effect is provided, which can be included into body care formula, especially in anti-cellulite and diet products;Purchase is certainly LIPOTEC company.
The entitled ethoxy urea of the INCI of HYDROVANCE in the present invention;Properties of product and application: ethoxy urea can Fabulous moistening effect is provided, the elasticity of skin is increased, improves the skin sense of formula;It can also enter hair by epidermis, repair Multiple internal sliver, therefore hair can be soaked and enhance hair quality.
The entitled siloxanes triol alginate esters/caffeine of the INCI of caffeine silanol C in the present invention, properties of product and Using: silanol and caffeine synergistic effect have solution rouge function outstanding.Cyclic annular adenosine phosphoric acid activation is promoted by element silicon Rouge is solved, the formation and accumulation of triglycerides are reduced by the inhibiting effect to lipoprotein lipase, while rebuilding skin histology, reaches tight Skin, anti-inflammatory and other effects.Suitable for weight reducing, body and skin of face consolidation remove the products such as eye pouch.
BN full name in the present invention isELITE BN;The entitled starch ocentyl succinic aluminium of an INCI/nitrogen Change boron;Properties of product and application: skin sense modifying agent combines boron nitride powder on the basis of DRY-FLO PC improves skin sense Good characteristics.The sliding sense of fabulous children and coverage effect are imparted, also there is better adhesiveness compared to DRY-FLO PC starch.
De Minshu full name in the present invention are as follows:De Minshu 143535;INCI title are as follows: Butylene Glycol, Pentylene Glycol, Hydroxyphenyl Propamidobenzoic Acid butanediol, 1,2- pentanediol, Hydroxyphenyl propyl amides benzoic acid;Properties of product and application: there is antihistamine, anti-irritant, the itching-relieving action (scabies as caused by dry Itch, the nursing of skin after the elderly's pruitus and bite by mosquitos);Effectively inhibit erythema, itch and mistake caused by histamine Quick reaction;It is good with other material combinations.
Sunset yellow and burnt sugar coloring in the present invention are colorant.
A kind of preparation method of the stoste with a variety of skin effects, comprising the following steps:
S1, water phase preparation:
By Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 Propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, hydrolyze silkworm Silk: 0.2%, it is added in the deionized water of part, water is heated to 90-95 DEG C in a stainless steel jacket water (J.W.) steam heating boiler, dimension 20min sterilizing is held, heating kettle is equipped with simple turbine stirrer, and raw material is made to accelerate dissolution, accelerates heat transfer, so that water is heated up, be heated to 90 DEG C of water phase is cooled to 72-75 DEG C, and to obtain A water phase stand-by;Long-time heating should be avoided, in order to avoid cause viscosity change, for supplement The moisture vapored away when heating and emulsification can be added 2% water by formula;
The preparation of S2, oily phase:
By vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, De Minshu: 0.1%, sunset It is yellow: 0.00015%, burnt sugar coloring: 0.0054%;Be added collet dissolving pan in, open steam heating, under constant agitation plus Heat makes it sufficiently melt or be uniformly dissolved to obtain oily mutually stand-by to 70-75 DEG C;Avoid excessively heat and long-time heating with Prevent material composition oxidation deterioration;
S3, emulsification:
A water phase being slowly added into oily phase, while homogenizer, after water adds, homogeneous blender is stirred for 5 minutes, Then be added through ultraviolet disinfection and not heated another part deionized water (water of the part is B water phase, B water phase+A water Phase=whole deionized water);The weight of B water phase can be measured in sunset phase pot or with metering pump-metered;
S4, cooling:
The cooling procedure of emulsion is realized by the stirring of scraper plate blender and the reflux of collet cooling water, using centrifugal pump- Cooling tower forced circulation reflux type effect is good;
The revolving speed of scraper plate blender is as slow as possible, and 1000L emulsifies the scraper plate blender revolving speed 20-30r/min of agitated kettle, When homogeneous blender starts emulsification stirring, many bubbles can be generated, the purpose being slowly stirred is that the bubble risen is made gradually to disappear It loses.
Further, the ratio (see the table below -1) of the A phase water in the present invention and B phase water has to selection suitably, generally, low The condensed emulsified cognition of viscosity makes the addition of next step B phase water be easy to carry out.
The ratio of table -1 A phase and B phase water
Currently preferred that A phase is compressed to lower value, A=0.2-0.3, B phase can be improved to 0.7-0.8.
Further, stirring is stronger when emulsification, and emulsifier can be lower, but emulsified body granular size and stirring are strong Degree and emulsifier have relationship, and universal law is as shown in table -2.
The relationship of -2 stirring intensity of table and granular size and emulsifier
Stirring intensity Granular size Emulsifier
Difference (craft or paddle stirring) Greatly (emulsification is poor) On a small quantity
Difference It is medium Middle amount
(colloid mill) by force It is medium Amount in as little as
(homogenizer) by force It is small Amount in as little as
Medium (craft or rotary propeller type) It is small In to a large amount
Difference It is superfine (clear) Very high amount
Excessive strong stirring might not be effective to reduction granular size, and is easily mixed into air, using medium When stirring intensity, with the available thin particle of phase inversion method, when being stirred using paddle or rotary propeller type, it should be noted that do not make air It stirs into emulsified body.
Ordinary circumstance is, advantageous to emulsifying using higher speed stirring when starting emulsification, terminates in emulsification and enters cooling After stage, then with medium speed or mixes slowly advantageous, stir always to room temperature, can reduce be mixed into bubble in this way.
Properties of product test:
1. the Detection of Stability of product
When studying and the stability of emulsified body system being discussed, there is famous Stokes (Stokes) equation:
V=2rr (p2-p1) × g/9 η
In formula: the sinking speed of particle (drop) in v- system
Medium viscosity in η-system
The radius (2 powers that the rr in this formula represents r) of particle (drop) in r- system
G- acceleration of gravity,
P1, p2 are respectively interior phase, the density of foreign minister.
Sinking speed v in formula is exactly the aggregation velocity of the particle (drop) in system, it is clear that if aggregation velocity η is big, The interior phase (oil mutually or water phase) of system is just easily accumulated on causes water-oil separating and unstable together, so, sinking speed Smaller, cream or emulsion system are just more stable;By formula it follows that working as interior phase and the foreign minister of system, i.e., oily phase and water phase Density difference (p2-p1) is cured hour, and system is more stable;When the particle (drop) of system is smaller, i.e., v is smaller, that is, oil droplet or water Drop is dispersed thinner, and v is just smaller, and system is more stable.So efficient emulsifying device, revolving speed should be made when preparing emulsified body There is a 3000rpm or more, the dispersion degree of system is high, and the stability of product is good and the glossy exquisiteness of appearance;But in formula system is situated between The viscosity of matter (i.e. foreign minister), sinking speed v are inversely proportional with η, i.e. the viscosity η of foreign minister is bigger, and v is smaller, and system is just more stable.Such as When preparing O/W type cream, it can be thickened by the way that hydrophilic macromolecular compounds are added in foreign minister (water phase) to improve the stabilization of cream Property.
For the stability for guaranteeing cosmetic product, design and experimental stage in formula can also strengthen sample Stability test, to judge its stability.
Method specifically: determine certain time interval (6h or for 24 hours, preferably for 24 hours), product is first stirred into high temperature (50 DEG C) in insulating box, taken out after the time of above-mentioned determination, restore room temperature, then (- 15 DEG C) are stirred into refrigerator, and pass through same Time, take out restore room temperature after, place into high-temperature incubator, so after recycling twice or thrice, observe product Stability shows that the formula design of the embodiment one of the product is the most reasonable, and the stability of each embodiment is as shown in following table -3.
The stability of each embodiment of table -3
Embodiment Embodiment one Embodiment two Embodiment three
Stability It is the most stable Stablize Difference
Wherein the stability of the product of embodiment 1 is best, is not any change, and occurs a small amount of sink in the product of embodiment two Then there is lamination slightly in starch, the product of embodiment three.
2. the hygienic chemistry index of product: " cosmetics safety technical specification " (version in 2015) Physico-chemical tests method is referred to, As a result as shown in table -4.
- 4 hygienic chemistry testing result of table
Inspection project Embodiment one Embodiment two Embodiment three
Arsenic ≤0.1mg/kg ≤0.1mg/kg ≤0.1mg/kg
Mercury ≤0.2mg/kg ≤0.2mg/kg ≤0.2mg/kg
Lead ≤10mg/kg ≤10mg/kg ≤10mg/kg
Methanol ≤5mg/kg ≤5mg/kg ≤5mg/kg
3. the microbiological indicator of product: " cosmetics safety technical specification " (version in 2015) microorganism detection method is referred to, As a result as shown in table -5.
- 5 microorganism detection result of table
Inspection project Embodiment one Embodiment two Embodiment three
Total plate count ≤1000CFU/g ≤1000CFU/g ≤1000CFU/g
Yeast and mold sum ≤10CFU/g ≤50CFU/g ≤100CFU/g
Thermotolerant coliform It does not detect It does not detect It does not detect
Staphylococcus aureus It does not detect It does not detect It does not detect
4. the performance test of product: selection volunteer 18, the age 25-30 years old, average age 28 years old;Volunteer is divided equally At 6 people in 3 groups, every group, 1-2 group is experimental group, and third group is control group, and corresponding volunteer is corresponding to use embodiment 1-3 Stoste;4th group of volunteer does not use any cosmetics;Continuous experiment 50 days, volunteer was used before and after cosmetics in every 10 days It compares.As a result as shown in table -6.
The performance test results of -6 product of table
Note: it because the skin quality of different users is different, tells in same test group more than half people, and default the group to make (such as the 10th day four volunteer's microgrooves in first group significantly reduce, skin shine improves, that is, default the group with effective Effect is that microgroove significantly reduces, skin shine improves), while all test groups are without any adverse reactions.
Volunteer of the embodiment of the present invention indicates stoste good penetrability of the invention, easily absorbs, clearly not using rear face Sticky, whitening, moistening effect are good, promote skin metabolism, and long-acting moisturizing, keep skin water profit smooth, flexible;
Wherein the stoste of the stability highest preferred embodiment 1 of embodiment 1 is preferred embodiment;
There is allergic phenomena in non-someone in whole subjects simultaneously, do not occur yet skin convulsion itch, shouting pain, the shapes such as redness Condition.Therefore, the present invention is mildly safe, can be used for a long time.
The preferred embodiment of the patent is described in detail above, but this patent is not limited to above-mentioned embodiment party Formula within the knowledge of one of ordinary skill in the art can also be under the premise of not departing from this patent objective It makes a variety of changes.

Claims (8)

1. a kind of stoste with a variety of skin effects, which is characterized in that by weight percentage, specific formula component is as follows: Water: 80.05445%, Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 propylene glycol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanilla Alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, hydrolysis silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, burnt sugar coloring: 0.0054%.
2. the stoste according to claim 1 with a variety of skin effects, which is characterized in that with a variety of skin effects Stoste, by weight percentage, specific formula component are as follows: water: 80.05445%, Genapol G-260:2%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, benzene Oxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, hydrolysis Silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, burnt sugar coloring: 0.0054%.
3. the stoste according to claim 1 with a variety of skin effects, which is characterized in that with a variety of skin effects Stoste, by weight percentage, specific formula component are as follows: water: 79.05445%, Genapol G-260:2%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 propylene glycol: 4%, decoyl ketone: 0.5%, propylene glycol: 4%, benzene Oxyethanol: 0.3%, TEA triethanolamine: 0.05%, vanillyl alcohol butyl ether: 1%, CO40:2.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl:1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, hydrolysis Silk: 0.2%, De Minshu: 0.1%, sunset yellow: 0.00015%, burnt sugar coloring: 0.0054%.
4. the stoste according to claim 1 with a variety of skin effects, which is characterized in that the present invention in water be go from Sub- water;If, because containing Ca2+, Mg2+ ion, under alkaline condition, generating the oxyhydroxide of calcium, magnesium using tap water, being A kind of cotton-shaped cohesion suspended matter often blocks the screen cloth of piping filter, causes dilute light buck when being put into emulsification agitated kettle It is unable to Channel Group.
5. the stoste according to claim 1 with a variety of skin effects, which is characterized in that the present invention in consideration to from Evaporation when sub- water heats and in whipping process, aggregate losses about 2%-3%, to accomplish stoste recovery rate 100%, often additionally Add 2%-3% moisture, supplements the loss of water.
6. a kind of preparation method of the stoste with a variety of skin effects, which comprises the following steps:
S1, water phase preparation:
By Genapol G-260:3%, Carbopol Ultrez U21:0.05%, SEPIMAX ZEN:0.2%, 1,3 the third two Alcohol: 3%, decoyl ketone: 0.5%, propylene glycol: 4%, Phenoxyethanol: 0.3%, TEA triethanolamine: 0.05%, hydrolyze silk: 0.2%, it is added in the deionized water of part, water is heated to 90-95 DEG C in a stainless steel jacket water (J.W.) steam heating boiler, maintains 20min sterilizing, heating kettle are equipped with simple turbine stirrer, and raw material is made to accelerate dissolution, accelerate heat transfer, so that water is heated up, be heated to 90 DEG C water phase be cooled to 72-75 DEG C to obtain A water phase stand-by;Long-time heating should be avoided, in order to avoid causing viscosity change, add for supplement The moisture vapored away when heat and emulsification can be added 2% water by formula;
The preparation of S2, oily phase:
By vanillyl alcohol butyl ether: 1%, CO40:1.5%, grapefruit essential oil: 0.04%, AQUAXYL:1%, Liporeductl: 1.5%, HYDROVANCE:1%, caffeine silanol C:2%, BN:0.5%, De Minshu: 0.1%, sunset yellow: 0.00015%, burnt sugar coloring: 0.0054%;It is added in collet dissolving pan, opens steam heating, heat under constant agitation To 70-75 DEG C, it is made sufficiently to melt or be uniformly dissolved to obtain oily mutually stand-by;Avoid excessively heat and long-time heating to prevent Only material composition oxidation deterioration;
S3, emulsification:
A water phase is slowly added into oily phase, while homogenizer, after water adds, homogeneous blender is stirred for 5 minutes, then Be added another part deionized water not heated through ultraviolet disinfection (water of the part is B water phase, B water phase+A water phase= Whole deionized water);The weight of B water phase can be measured in sunset phase pot or with metering pump-metered;
S4, cooling:
The cooling procedure of emulsion is to realize that 1000L emulsifies agitated kettle by the stirring of scraper plate blender and the reflux of collet cooling water Scraper plate blender revolving speed 20-30r/min, homogeneous blender start emulsification stirring when, many bubbles can be generated, be slowly stirred Purpose be make rise bubble gradually disappear.
7. the preparation method of the stoste according to claim 6 with a variety of skin effects, which is characterized in that in the present invention A phase water and B phase water ratio: A=0.2-0.3, B phase=0.7-0.8.
8. the preparation method of the stoste according to claim 6 with a variety of skin effects, which is characterized in that stirred when emulsification It mixes more strongly, emulsifier can be lower, but emulsified body granular size and stirring intensity and emulsifier have relationship, this Invention is advantageous to emulsifying using higher speed stirring when starting to emulsify, after emulsification end enters cooling stage, then with medium Speed mixes slowly favorably, stirs always to room temperature, can reduce be mixed into bubble in this way.
CN201811419104.0A 2018-11-26 2018-11-26 A kind of stoste and preparation method thereof with a variety of skin effects Pending CN109498509A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115590772A (en) * 2022-10-31 2023-01-13 北京茂思商贸有限公司(Cn) Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof

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CN107233282A (en) * 2017-06-20 2017-10-10 诺斯贝尔化妆品股份有限公司 A kind of collagen, which compacts, lifts plentiful shining color face cream

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CN107233282A (en) * 2017-06-20 2017-10-10 诺斯贝尔化妆品股份有限公司 A kind of collagen, which compacts, lifts plentiful shining color face cream

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