CN109479972A - Improve the baby milk powder companion and preparation method thereof of gastrointestinal tract - Google Patents

Improve the baby milk powder companion and preparation method thereof of gastrointestinal tract Download PDF

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Publication number
CN109479972A
CN109479972A CN201811502914.2A CN201811502914A CN109479972A CN 109479972 A CN109479972 A CN 109479972A CN 201811502914 A CN201811502914 A CN 201811502914A CN 109479972 A CN109479972 A CN 109479972A
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China
Prior art keywords
milk powder
gastrointestinal tract
orange peel
dried orange
baby milk
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Pending
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CN201811502914.2A
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Chinese (zh)
Inventor
薛玉玲
朱宏
王世杰
冯丽莉
张栋
荀萍
荀一萍
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Shijiazhuang Junlebao Dairy Co Ltd
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Shijiazhuang Junlebao Dairy Co Ltd
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Priority to CN201811502914.2A priority Critical patent/CN109479972A/en
Publication of CN109479972A publication Critical patent/CN109479972A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/156Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a kind of baby milk powder companions for improving gastrointestinal tract, it is mainly made of lactobacillus paracasei N1115, the whole oat four of curing, yam flour and dried orange peel infusion, the invention also discloses the preparation methods of baby milk powder companion for improving gastrointestinal tract a kind of, and sequence carries out according to the following steps for it: (1) thallus (3) freeze-drying (4) milling is collected in actication of culture and Multiplying culture (2).In the present invention by probiotics together with aid digestion, row's pneumatosis oat, Chinese yam and dried orange peel compatibility, and the compatibility of oat, Chinese yam and dried orange peel is reasonable, cooperate with baby formula milk powder, can effectively improve infant and the bowel symptoms such as flatulence even intestinal colic, constipation, diarrhea often occur.Oat, Chinese yam can protect thallus simultaneously, keep vigor of the bacterium powder within the shelf-life, improve the stability and validity of bacterium powder.

Description

Improve the baby milk powder companion and preparation method thereof of gastrointestinal tract
Technical field
The invention belongs to field of food, are related to a kind of baby milk powder companion, specifically, being a kind of improvement gastrointestinal tract Baby milk powder companion and preparation method thereof.
Background technique
After newborn's birth, since the abilities of digestive and absorption of intestinal tissue is weak, and the intake and acquisition of nutrition are turned by placenta It is changed to enteron aisle, therefore, enteron aisle faces huge pressure.Since food intake and enteron aisle design feature and digestion and absorption function are mutual Often there are the bowel symptoms such as flatulence even intestinal colic, constipation, diarrhea in effect, infant.
Baby formula milk powder is full of nutrition, is the ultimate food of no breast milk or breast milk deficiency infant close to breast milk.I State's about 17,000,000 baby dues every year, the market annual requirement of baby milk powder is about at 300,000 tons or so.Although infant Formula milk is to carry out modernization overlay using breast milk as standard to milk, it is made close to breast milk, to meet infant to the maximum extent and disappear Change absorption and nutritional need.But the bowel symptoms incidence of the infant of edible baby formula milk powder, which is higher than breast milk, feeds It supports, how effectively to mitigate the edible infant's gastrointestinal tract burden of formula milk, have become a great problem.
Probiotics is widely applied in terms of preventing or treating a variety of intestines problems as the microorganism beneficial to body.Benefit Raw bacterium develops animal early stage Intestinal Morphology, and the intestinal growths process such as epithelial cell proliferation, immune system differentiation has a major impact. Intervened by microorganism, especially probiotics is intervened, and effectively enhances the abilities of digestive and absorption of enteron aisle.If by probiotics and tool There is aid digestion, row's pneumatosis important component compatibility together, plays its synergistic effect, be effectively improved the same of infant's bowel symptoms When, and infant's intestinal growth can be promoted, it is of great significance for the healthy development of infant.
Summary of the invention
The invention aims to the enterogastric diseases for the infant for eating baby formula milk powder in the prior art The problems such as incidence is high proposes a kind of baby milk powder companion for improving gastrointestinal tract, to improve edible baby milk powder Infant's gastrointestinal tract promotes the intestinal growth of infant.
It is a further object to provide the preparation methods of baby milk powder companion for improving gastrointestinal tract a kind of.
To achieve the above object, used technical solution is as follows by the present invention:
A kind of baby milk powder companion improving gastrointestinal tract, the raw material that its effective component is made specifically include that lactobacillus paracasei N1115, the whole oat four of curing, yam flour and dried orange peel infusion, the lactobacillus paracasei N1115, curing whole oat four, The amount ratio of yam flour and dried orange peel infusion are as follows: 109~1011CFU:50~70g:50~70g:1L.
As a kind of restriction of the invention, the dried orange peel infusion the preparation method comprises the following steps: 35 ~ 45g dried orange peel be added 0.8 ~ 1.2 In L pure water, 75 ~ 85 DEG C of 30 ~ 50min of immersion filter to obtain dried orange peel infusion.
The present invention also provides the preparation methods of baby milk powder companion for improving gastrointestinal tract a kind of, it is according to the following steps Sequence carries out:
(1) actication of culture and Multiplying culture
0.8 ~ 1.2mL lactobacillus paracasei N1115 is inoculated into 8 ~ 10mLMRS fluid nutrient medium and is activated, the bacterium that will have been activated Kind it is inoculated in Multiplying culture in 0.8 ~ 1.2L high-density culture medium, and carries out viable count detection, until viable count is up to 109~1011 When CFU/L, bacterium solution A is obtained;Every 1L high-density culture medium is mainly made of following raw material: glucose 20g, yeast powder 20g, Sodium citrate/sodium acetate/dipotassium hydrogen phosphate buffer salt 0.09mol, MnSO4•5H2O 50mg, pure water 1L;
(2) thallus is collected
Bacterium solution A carries out the high revolving speed of low temperature in 4.5 ~ 8 DEG C, 12500 ~ 14000rpm and is centrifuged 8 ~ 15min, discards supernatant liquid, obtains bacterium Mud B;
(3) it is freeze-dried
Bacterium mud B is added with bacterium solution A isometric solution C, obtains material D after mixing, vacuum freeze drying is carried out, must freeze Dry product E;Every 1L solution C is mainly made of following raw material: 50~70g of whole oat four of curing, 50 ~ 70g of yam flour, dried orange peel Infusion 1L;
(4) it is milled
Dried frozen aquatic products E is milled, crosses 45 ~ 60 meshes to get the baby milk powder companion for improving gastrointestinal tract.
Limited as another kind of the invention, the dried orange peel infusion the preparation method comprises the following steps: 35 ~ 45g dried orange peel be added 0.8 ~ In 1.2 L pure water, 75 ~ 85 DEG C of 30 ~ 50min of immersion filter to obtain dried orange peel infusion.
The present invention is there are also a kind of restriction, vacuum freeze drying described in step (3), successively carries out according to the following steps:
1. pre-freeze
Material D is subjected to pre-freeze under conditions of -45~-40 DEG C of plate layer temperature, until when temperature≤- 35 DEG C of material, material D Product freeze reality completely;
2. primary drying phase
It is that temperature is to slowly warm up to -30~-26 DEG C by 5 DEG C/30min with heating rate, maintains this temperature until plate layer and product Between heat exchange terminate substantially, vacuum degree has descended to≤0.02MPa, and fluctuating range≤0.002 MPa, cold well Temperature drops to -70 DEG C, and primary drying phase terminates;
3. the parsing-desiccation stage
Temperature is directly raised to 10 DEG C, is evaporated the moisture of remaining, until water content is 3.5~4%, vacuum freeze drying terminates.
Due to the adoption of the above technical solution, compared with prior art, acquired technological progress is the present invention:
Lactobacillus paracasei N1115 is known strain in the present invention, is a kind of probiotics, has immunoregulation effect.
In the present invention by probiotics together with aid digestion, row's pneumatosis oat, Chinese yam and dried orange peel compatibility, Er Qieyan The compatibility of wheat, Chinese yam and dried orange peel is reasonable, cooperates with baby formula milk powder, can effectively improve infant and flatulence even intestines often occurs The bowel symptoms such as colic pain, constipation, diarrhea.Oat, Chinese yam simultaneously can substitute freeze drying protectant protection thallus, keep bacterium powder While vigor in shelf-life, harm of the unnecessary ingredient to infant is avoided, lactobacillus paracasei N1115 is being frozen Damage during dry is reduced, and freeze-drying survival rate increases, while it is reduced as the vigor attenuation rate of probiotic powder, is greatly improved The stability and validity of bacterium powder.
Contain oligofructose in oat, the content of whole oat four oligofructose in 50~60g/ L has well thallus Keep active effect.The purpose that whole oat four is cured is to be easier to absorb, and the starch otherwise included is not easy by people Body is digested and assimilated.
Chinese yam is a kind of plant of integration of drinking and medicinal herbs, contains a variety of nutriments such as protein, free amino acid, polysaccharide and work Property ingredient, nutrition and medical value are approved by people.Its mannose contained, galactolipin, fructose etc. form Chinese yam polysaccharide, Have with oat cooperation to lactobacillus paracasei and preferably keeps active effect.Chinese yam trace elements zn also rich in, Fe, The microelements such as Mn, Cu, Se and macroelement Ca, microelement has activation to the enzyme of internal digestive system, to promote Digestion adjusts gastrointestinal tract.Diastase in active constituent contained by Chinese yam can using playing the role of promoting digestion when gasteremphraxis To remove the symptom having a stomach upset, be conducive to improve the function that taste are digested and assimilated.
Dried orange peel, containing ingredients such as volatile oil, polysaccharide, flavonoids, the volatile oil contained by it has mild stimulation to make gastrointestinal tract With, can promote the secretion of digestive juice, exclude pneumatosis in intestinal tube, increase appetite.It has invigorating the spleen qi-regulating with Chinese yam compatibility, nourishing the stomach Effect.
Detailed description of the invention
Fig. 1 improves number of viable testing result of the baby milk powder companion of gastrointestinal tract in 18 months.
Specific embodiment
The present invention is described in further detail below in conjunction with specific embodiment.
The baby milk powder companion of the improvement gastrointestinal tract of embodiment 1 ~ 5
Embodiment 1 ~ 5 is respectively a kind of baby milk powder companion for improving gastrointestinal tract, and difference is only that the type and again of raw material It is different to measure number, specifically see the table below:
The usage and dosage of any one of embodiment 1 ~ 5 baby milk powder companion for improving gastrointestinal tract are as follows: with made infant Formula milk reconstitutes, and takes within one day 1 time, a 2g, the flatulence that infant often occurs can be effectively improved for 1 ~ 2 day by taking, even Intestinal colic, constipation, diarrhea etc. promote infantile health development because of gastrointestinal symptom caused by eating baby formula milk powder.
A kind of preparation method for the baby milk powder companion for improving gastrointestinal tract of embodiment 6
Sequence carries out according to the following steps for it:
(1) actication of culture and Multiplying culture
1mL lactobacillus paracasei N1115 is inoculated into 9 mLMRS fluid nutrient mediums and is activated, the strain activated is inoculated in Multiplying culture in 1L high-density culture medium, and carry out viable count detection, until viable count is up to 109~1011 When CFU/L, bacterium is obtained Liquid A;Every 1L high-density culture medium is mainly made of following raw material: glucose 20g, yeast powder 20g, sodium citrate/acetic acid Sodium/phosphorus acid hydrogen dipotassium buffer salt 0.09mol, MnSO4•5H2O 50mg, pure water 1L;
(2) thallus is collected
Bacterium solution A carries out the high revolving speed of low temperature in 5 DEG C, 12500rpm and is centrifuged 10min, discards supernatant liquid, obtains bacterium mud B;
(3) it is freeze-dried
Bacterium mud B is added with bacterium solution A isometric solution C, obtains material D after mixing, vacuum freeze drying is carried out, must freeze Dry product E;Every 1L solution C is mainly made of following raw material: the whole oat four 50g of curing, yam flour 70g, dried orange peel infusion 1L;
Wherein vacuum freeze drying successively carries out according to the following steps:
1. pre-freeze
Material D is subjected to pre-freeze under conditions of -45~-40 DEG C of plate layer temperature, until when temperature≤- 35 DEG C of material, material D Product freeze reality completely;
2. primary drying phase
It is that temperature is to slowly warm up to -30~-26 DEG C by 5 DEG C/30min with heating rate, maintains this temperature until plate layer and product Between heat exchange terminate substantially, vacuum degree has descended to≤0.02MPa, and fluctuating range≤0.002 MPa, cold well Temperature drops to -70 DEG C, and primary drying phase terminates;
3. the parsing-desiccation stage
Temperature is directly raised to 10 DEG C, is evaporated the moisture of remaining, until water content is 3.5~4%, vacuum freeze drying terminates.
(4) it is milled
Dried frozen aquatic products E is milled, crosses 50 meshes to get the baby milk powder companion for improving gastrointestinal tract.
Embodiment 7 ~ 11 improves the preparation method of the baby milk powder companion of gastrointestinal tract
Embodiment 7~11 is respectively the preparation method of baby milk powder companion for improving gastrointestinal tract a kind of, and the operating procedure is equal Same as Example 6, the temperature that is only centrifuged, revolving speed, time, the control parameters such as raw material composition are different, specifically see the table below:
A kind of preparation method of the dried orange peel infusion of embodiment 12
40g dried orange peel is added in 1L pure water, and 80 DEG C of immersion 40min filter to obtain dried orange peel infusion.
The preparation method of 13 ~ 17 dried orange peel infusion of embodiment
Embodiment 13 ~ 17 is respectively a kind of preparation method of dried orange peel infusion, and the operating procedure is identical as embodiment 12, Only the control parameters such as the dosage, temperature of raw material, time are different, specifically see the table below:
Embodiment 18 takes infant's gastrointestinal health situation of the baby milk powder companion of the present invention for improving gastrointestinal tract
This example baby milk powder companions for improving gastrointestinal tract described in any item to embodiment 1 ~ 5 improve infant's flatulence The case where symptom, devises test-meal experiment:
Experimental method:
1, infant 10 that 10 6 ~ 18 months edible formula milks have the gastrointestinal symptoms such as flatulence are screened.
2, simple randomization is divided into 5 people of intervention group, and 5 people of control group carries out random, double blind placebo parallel control experiment, Using milk powder plus the baby milk powder companion of the present invention for improving gastrointestinal tract as laboratory sample, milk powder is control sample, is eaten daily With one bag (2g), continuous test-meal 2 months, to assess the baby milk powder companion of improvement gastrointestinal tract of the invention to infant's stomach and intestine The influence in road.
3, the flatulence situation of infant is monitored daily, while also excrement number and excrement state is carried out Observation.
Experimental result:
By test-meal in 2 months, tested infant did not occurred significant adverse reaction, good security.Experimental group can be observed Tested infant gastrointestinal tract flatulence situation alleviate, defecation frequency increase, appetite increase.
Flatulence situation is as follows:
Parent evaluates tested infant's flatulence degree.Intestinal tympanites degree is evaluated with 5 points of systems, 5 points are tested baby children Youngster shows the degree of flatulence, and 1 point is not observe flatulence phenomenon.From following table as can be seen that the flatulence phenomenon of experimental group infant obtains To being relieved.Although and infant's flatulence phenomenon of control group is alleviated with the increase of week old, is not so good as experimental group Alleviation degree is high.
Evaluation table of 1 parent of table to tested infant's flatulence degree
Excrement number:
Compared with before drink, experimental group infant is drinking the first of the baby milk powder companion of the present invention for improving gastrointestinal tract Week, 4th week and after the 8th week, defecation frequency increased, and experimental group infant is compared with control group infant, and the 4th The defecation frequency in week has significant difference, is specifically shown in Table 2.
The variation of the tested infant's excrement number of table 2
Excrement state:
Parent evaluates tested infant's excrement state.Excrement state degree are evaluated with 5 points of systems, 5 points are high rigidity, 1 point It is watery.Compared with before drink, experimental group infant is drinking first week, 4th week and after the 8th week, and the hardness of excrement is gradually Soften;And experimental group infant starts in the stool hardness of second week significantly less than control group;Specifically it is shown in Table 3.
Evaluation table of 3 parent of table to tested infant's excrement state
Embodiment 19 improves baby milk powder companion viable count detection test within the shelf-life of gastrointestinal tract
Viable count of this example baby milk powder companions for improving gastrointestinal tract described in any item to embodiment 1 ~ 5 in 18 months Amount has carried out tracing detection, and testing result refers to Fig. 1, although the baby milk powder companion of the present invention for improving gastrointestinal tract exists In 18 months shelf-lifves, number of viable is in be gradually reduced trend, but remain at 10 when 18 months expired8CFU/g or more.

Claims (5)

1. a kind of baby milk powder companion for improving gastrointestinal tract, it is characterised in that: the raw material that its effective component is made specifically includes that Lactobacillus paracasei N1115, the whole oat four of curing, yam flour and dried orange peel infusion are the lactobacillus paracasei N1115, ripe The amount ratio of the whole oat four of change, yam flour and dried orange peel infusion are as follows: 109~1011CFU:50~70g:50~70g:1L.
2. improving the baby milk powder companion of gastrointestinal tract as described in claim 1, it is characterised in that: the system of the dried orange peel infusion Preparation Method are as follows: 35 ~ 45g dried orange peel is added in 0.8 ~ 1.2 L pure water, and 75 ~ 85 DEG C of 30 ~ 50min of immersion filter to obtain dried orange peel infusion.
3. it is a kind of improve gastrointestinal tract baby milk powder companion preparation method, it is characterised in that: it according to the following steps sequence It carries out:
(1) actication of culture and Multiplying culture
0.8 ~ 1.2mL lactobacillus paracasei N1115 is inoculated into 8 ~ 10mLMRS fluid nutrient medium and is activated, the bacterium that will have been activated Kind it is inoculated in Multiplying culture in 0.8 ~ 1.2L high-density culture medium, and carries out viable count detection, until viable count is up to 109~1011 When CFU/L, bacterium solution A is obtained;Every 1L high-density culture medium is mainly made of following raw material: glucose 20g, yeast powder 20g, Sodium citrate/sodium acetate/dipotassium hydrogen phosphate buffer salt 0.09mol, MnSO4•5H2O 50mg, pure water 1L;
(2) thallus is collected
Bacterium solution A carries out the high revolving speed of low temperature in 4.5 ~ 8 DEG C, 12500 ~ 14000rpm and is centrifuged 8 ~ 15min, discards supernatant liquid, obtains bacterium Mud B;
(3) it is freeze-dried
Bacterium mud B is added with bacterium solution A isometric solution C, obtains material D after mixing, vacuum freeze drying is carried out, must freeze Dry product E;Every 1L solution C is mainly made of following raw material: 50~70g of whole oat four of curing, 50 ~ 70g of yam flour, dried orange peel Infusion 1L;
(4) it is milled
Dried frozen aquatic products E is milled, crosses 45 ~ 60 meshes to get the baby milk powder companion for improving gastrointestinal tract.
4. improving the preparation method of the baby milk powder companion of gastrointestinal tract as claimed in claim 3, it is characterised in that: the dried orange peel Infusion the preparation method comprises the following steps: 35 ~ 45g dried orange peel be added 0.8 ~ 1.2 L pure water in, 75 ~ 85 DEG C of 30 ~ 50min of immersion filter old Severe edema due to hypofunction of the spleen immersion liquid.
5. improving the preparation method of the baby milk powder companion of gastrointestinal tract as claimed in claim 3, it is characterised in that: step (3) Described in vacuum freeze drying, according to the following steps successively carry out:
1. pre-freeze
Material D is subjected to pre-freeze under conditions of -45~-40 DEG C of plate layer temperature, until when temperature≤- 35 DEG C of material, material D Product freeze reality completely;
2. primary drying phase
It is that temperature is to slowly warm up to -30~-26 DEG C by 5 DEG C/30min with heating rate, maintains this temperature until plate layer and product Between heat exchange terminate substantially, vacuum degree has descended to≤0.02MPa, and fluctuating range≤0.002 MPa, cold well Temperature drops to -70 DEG C, and primary drying phase terminates;
3. the parsing-desiccation stage
Temperature is directly raised to 10 DEG C, is evaporated the moisture of remaining, until water content is 3.5~4%, vacuum freeze drying terminates.
CN201811502914.2A 2018-12-10 2018-12-10 Improve the baby milk powder companion and preparation method thereof of gastrointestinal tract Pending CN109479972A (en)

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