CN1092681A

CN1092681A - " Ximeng " granule preparation and preparation method thereof

Info

Publication number: CN1092681A
Application number: CN 93118021
Authority: CN
Inventors: 颜德先
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-09-21
Filing date: 1993-09-21
Publication date: 1994-09-28

Abstract

The present invention is " Ximeng " granule preparation and preparation method thereof.It is to be raw material with " west cover No. one " medicinal Rhizoma Dioscoreae esculentae, through over-sampling, cleaning, immersion, centrifugation, alcohol extraction, mixing concentrate, the refining a kind of graininess electuaries that form of technology such as sugaring, molding.It contains hemoporphyrin, folic acid, a large amount of vitamin Ks, B ₁, B ₂, B ₁₂, C, and multiple human body trace elements necessary and 16 seed amino acids.To the human body hematopoietic function, it is all beneficial to purify the blood.Especially the control to cancers such as hemorrhage and leukemia all has effect preferably.And medicine source drug effect is all reliably guaranteed, and technology is simple, invest little, the yield advantages of higher.

Description

" Ximeng " granule preparation and preparation method thereof

The present invention is a kind of medicinal granule and preparation method thereof.

Through looking into newly as can be known, at present domestic do not have similar new drug, the similar medicine of drug effect to have only the hormones prednisone, but bigger toxic and side effects, manufacturing process complexity and difficult by shortcomings such as patient's acceptance are arranged.

The purpose of this invention is to provide that a kind of medicine source is abundant, cost is low, yield is high, technology is simple, have no side effect, can improve immunocompetence and can play a role in health care again, to cancer patients such as treatment acute idiopathic thrombocytopenic purpura and leukemia put, effective newtype drug after the chemotherapy.

The present invention adopts at home that the stem and leaf of " west is covered No. one " medicinal Rhizoma Dioscoreae esculentae of successful introduction is a primary raw material, sees accompanying drawing through a kind of electuary medicine, its technology of being processed into.

Advantage of the present invention is, with existing similar medicine prednisone relatively, not only have no side effect, technology is simple but also contain hemoporphyrin, folic acid, jalapinolic acid, a large amount of vitamin K, C, B ₁, B ₂, B ₁₂, and the trace element of multiple needed by human and 16 seed amino acids etc.Can purify the blood, health invigorating, the hemostasis of YIN nourishing removing heat from blood and blood all has obvious curative effects to all hemorrhages.

Its enforcement is as follows;

Stem and leaf, the corrupt impurity of removal of at first choosing fresh " west is covered No. one " medicinal Rhizoma Dioscoreae esculentae clean up with tap water, steeped 10-15 minute with 2% phosphoric acid solution, after cleaning once more with cold boiled water, stainless-steel grinding machine homogenate 5 minutes (the serosity pH value is 6), add 3000 milliliters in cold boiled water with 1000 gram serosity, stirred 12-24 hour, the homogenate diluent is gone up running 20 minutes at centrifuge (rotating speed is 2000rpm), it is stand-by to obtain supernatant (water extract); Leave and take precipitate, under agitation slowly add 95% ethanol (about 1.8 times), make pure content reach 60%, standing over night, reuse high pressure vacuum filter leaching alcohol extract discards slag.Water extract and alcohol extract are mixed, and the back that filters out impurities concentrates (temperature＜60 ℃) to extract relative density with the efficient film concentrator and reaches 1.35-1.45, recovery ethanol.Concentrated solution is placed 1-5 ℃ chamber, Tibetan cold preservation 24 hours, remove precipitation and promptly get drug extract: extractum.Qualified sucrose is placed pulverizing in dry 1-2 hour about 60 ℃, add in the extractum in 5: 1 ratios, mix homogeneously is adjusted humidity with about 70% ethanol again, becomes soft material, makes the granule of 12-16 order size again.Under 60 ℃ of left and right sides temperature dry 2-3 hour, promptly get the electuary granule after the 12-16 mesh sieve, be packed as a pouch with per 15 grams at last.

Claims

1, " Ximeng " granule preparation and preparation method thereof, its feature and preparation technology are:

Sampling → clean → soaking disinfection → cleaning → pulverizing → dilution → from

Soak: 2%H3PO4; Thickening temperature: less than 60 ℃;

Refrigerated storage temperature: 1-5 ℃; Granular size: 12-16 order.