CN109195665A - 针对ctla4的单域抗体及其衍生蛋白 - Google Patents

针对ctla4的单域抗体及其衍生蛋白 Download PDF

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CN109195665A
CN109195665A CN201780030832.XA CN201780030832A CN109195665A CN 109195665 A CN109195665 A CN 109195665A CN 201780030832 A CN201780030832 A CN 201780030832A CN 109195665 A CN109195665 A CN 109195665A
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seq
ctla4
antibody
binding protein
cdr2
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CN109195665B (zh
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徐霆
汪皛皛
李洁
吴海燕
高丽
储倩
白玉
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Suzhou Alphamab Co Ltd
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Abstract

本发明涉及医药生物领域，公开了针对CTLA4的单域抗体及其衍生蛋白。具体而言，本发明公开了一种CTLA4结合蛋白及其用途，特别是在治疗和/或预防CTLA4相关疾病例如肿瘤中的用途。

Description

PCT国内申请，说明书已公开。

Claims (27)

  1. PCT国内申请，权利要求书已公开。
CN201780030832.XA 2016-05-19 2017-05-19 针对ctla4的单域抗体及其衍生蛋白 Active CN109195665B (zh)

Applications Claiming Priority (3)

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CN2016103325907 2016-05-19
CN201610332590.7A CN107400166A (zh) 2016-05-19 2016-05-19 针对ctla4的单域抗体及其衍生蛋白
PCT/CN2017/085038 WO2017198212A1 (zh) 2016-05-19 2017-05-19 针对ctla4的单域抗体及其衍生蛋白

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CN109195665A true CN109195665A (zh) 2019-01-11
CN109195665B CN109195665B (zh) 2022-09-09

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US (2) US11091549B2 (zh)
EP (1) EP3459597B1 (zh)
JP (2) JP2019522489A (zh)
CN (2) CN107400166A (zh)
DK (1) DK3459597T3 (zh)
ES (1) ES2931223T3 (zh)
FI (1) FI3459597T3 (zh)
WO (1) WO2017198212A1 (zh)

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WO2023066401A1 (zh) * 2021-10-21 2023-04-27 江苏诺迈博生物医药科技有限公司 一种特异性结合人ctla4的抗体及包含其的药物和试剂盒

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CN110407942B (zh) * 2018-04-27 2022-02-22 苏州康宁杰瑞生物科技有限公司 针对kn044的单域抗体
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