CN109125208A - Micro- solidifying anti-ageing Essence of pearl of one kind and preparation method thereof - Google Patents
Micro- solidifying anti-ageing Essence of pearl of one kind and preparation method thereof Download PDFInfo
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The present invention relates to a kind of micro- solidifying anti-ageing Essences of pearl and preparation method thereof, being intended to provide one kind enables aging ingredient slowly to discharge in skin surface, it is deeply infiltrated into keratoderma, functional component is capable of the anti-ageing Essence of storage-stable before use simultaneously, and the Essence is composed of the following components: A phase: appropriate amount of deionized water；B1 phase: emollient 3~7%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.005-0.05%；B2 phase: emollient 2~9%, antidotal agent 0.11~3%；B3 phase: emollient 0.3~2%；C1 phase: anti-inflammatory agent 0.02~0.6%, moisturizer 7.4~19.8%；C2 phase: appropriate deionized water, suspending agent 0.1~0.5%；C3 phase: appropriate deionized water, pH adjusting agent 0.01~0.14%；C4 phase: antidotal agent 0.7~9.5%, skin conditioning agent 0.05~2%；D phase: antidotal agent 0.01-1%.Belong to technical field of skin care.
Description
Technical field
The invention discloses a kind of micro- solidifying anti-ageing Essences of pearl and preparation method thereof, belong to cosmetic technical field.
Background technique
Essence class skin protection cosmetics is mainly made of water conservation ingredient and nutritional ingredient, with reach cleaning, eliminate bad smell,
Skin care, beauty and the water-retaining property and soft and moist property that improve skin, and have the quality such as safety, stability, usability, validity
Characteristic.
In " modern cosmetics science and technology ", " cosmetic formulations workshop manual ", " surfactant answering in formula
With " etc. in books, the preparation process of essence class cosmetics routine is will to be retained ingredient to be dissolved in deionized water, and dissolution is complete
Afterwards, nutritional ingredient is added, is stirred evenly.If contain the ingredient of oily phase, need to add emulsifier (surfactant), leads to
The mixing of Over emulsfication homogeneous, water phase and oil phase is integrated.And emulsifying homogeneous is usually to utilize dynamic high-pressure microjet homogeneous
Machine carries out high-pressure homogeneous.High pressure homogenizer is the powerful shearing force being subject to when passing through narrow gap using liquid at high speed, to metal
Impulsive contact force is generated when parts at high speeds, a series of comprehensive works generated by high pressure such as hole explosive force generated by static pressure bust
With by oil mixing with water.It need to be recycled repeatedly using high-pressure homogeneous, a large amount of heat can be generated, cooling equipment need to be equipped with, therefore energy consumption is high,
Complex process.Therefore, using low energy consumption, the preparation method of simple process, while obtaining grease phase and uniformly mixing and stable
Essence is this field technical issues that need to address.
In addition, uniform for conventional hybrid essence (aqua class essence, emulsifying essence) containing aging ingredient, resists
Aging ingredient is scattered in solvent, when using product, when essence is applied to skin surface initial stage, aging ingredient with solvent into
Enter skin, but as solvent evaporates at any time, many aging ingredients cannot effectively penetrate to the skin cuticula performance in fact
Border effect wastes many effect ingredients, and ideal anti-ageing effect is not achieved.Senile-resistant efficacy ingredient is in external environment simultaneously
Under be easy to inactivate because itself is unstable, therefore, slow release can be reached by developing one kind, while functional component is before use
The essence dosage form for capableing of storage-stable seems extremely important.
Summary of the invention
In view of the above deficiencies, the object of the present invention is to provide one kind, and aging ingredient to be enable slowly to release in skin surface
It puts, is deeply infiltrated into keratoderma, while functional component is capable of the anti-ageing essence agent of storage-stable before use.
For this purpose, first technical solution provided by the present application is such that
A kind of micro- solidifying anti-ageing Essence of pearl, by A phase component, B1 phase component, B2 phase component, B3 phase component, C1 phase component, C2
Phase component, C3 phase component, C4 phase component and D phase component composition, it is each according to micro- solidifying anti-ageing Essence overall weight percent meter of pearl
Main component in phase and its account for Essence total weight percentage composition are as follows:
A phase: appropriate amount of deionized water；
B1 phase: emollient 3~7%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.005-
0.05%；
B2 phase: emollient 2~9%, antidotal agent 0.11~3%；
B3 phase: emollient 0.3~2%；
C1 phase: anti-inflammatory agent 0.02~0.6%, moisturizer 7.4~19.8%；
C2 phase: appropriate deionized water, suspending agent 0.1~0.5%；
C3 phase: appropriate deionized water, pH adjusting agent 0.01~0.14%；
C4 phase: antidotal agent 0.7~9.5%, skin conditioning agent 0.05~2%；
D phase: antidotal agent 0.01-1%.
It wherein, further include odorant Roman chamomile caul-fat 0.001-0.05% in the B2 phase.
Emollient is pentaerythrite four (thylhexoic acid) ester in the B1 phase；Emollient is docosyl alcohol in the B2 phase
With the combination of one or both of dimethyl silicone polymer, paraffin, antidotal agent is ubiquinone // tocopherol acetate //C12-
15 alcohol benzoic ethers // tocopherol acetate //one or both of C12-15 alcohol benzoic ether or dipalmitoyl hydroxyproline
Combination；Emollient in the B3 phase is Parleam.
Moisturizer is one of dipropylene glycol, glycerol, 1,3- propylene glycol, 1,2- hexylene glycol or any in the C1 phase
Combination；Anti-inflammatory agent is one of allantoin or dipotassium glycyrrhizinate or combination in C1 phase.
The C1 phase further includes chelating agent EDETATE SODIUM 0.01~0.15%, and antioxidant parahydroxyacet-ophenone 0.4~
0.8%.
Suspending agent is carbomer in the C2 phase；PH adjusting agent is sodium hydroxide in the C3 phase；The C4 phase
Middle antidotal agent is Argireline, palmityl tripeptides -5, one kind or any combination of decarboxylation carnosine HCl, skin conditioning agent
For golden yellow camomile extract.
The D phase further includes moisturizer 0.1-2%, and moisturizer is aloe barbadensis Miller leaf extract, radix sophorae extraction
Object, lycium barbarum berry extract, Echinacea angustifolia extract, the composition of HERBA DENDROBII stem extraction or the group with hydrolecithin
It closes.
Antidotal agent is carnosine in the D phase.
Further, antidotal agent also includes that puncture vine berry extract or green colored grace south tomato bark extract in the D phase
One of object or combination.
A kind of preparation method of micro- solidifying anti-ageing Essence of pearl, comprising the following steps:
1) deionized water in A phase component is added in emulsion pot, stirring is warming up to 75-80 DEG C；
2) by B1 phase component mixing homogeneous 2-3min to no fine particle that is uniformly dispersed, B2 phase component, B3 phase component are added
Enter in B1 phase component, stirring is warming up to 70-75 DEG C to being dissolved as transparent oil-phase solution；
3) 75-80 DEG C of emulsion pot is kept, slowly oil-phase solution made from step 2) is added by mixing speed 80-120rpm
In the water phase of step 1), stirring to oil is mutually separated into fine particle, adds oily phase, and mixing speed 60-80rpm stirs 10-
15min is to forming uniform oil droplet particle；
4) steam valve for closing emulsion pot is opened and freezes water valve, unlatching rapid cooling, in temperature-fall period, mixing speed
100rpm is cooled to 35-45 DEG C, forms uniform oil droplet particle；
5) C1 phase, C4 phase, D phase component are added in emulsion pot, is stirred evenly, C2 component is added, improve mixing speed extremely
140-160rpm stirs 10-15min, and C3 component is added, and improves mixing speed to 180-200rpm, stirs 15-20min into
With it is complete, stir evenly, can discharge.
Compared with prior art, the present invention has the advantage that
(1) present invention, which does not need high pressure homogenizer, makes grease mix homogeneous, but uses grease phase and suspending agent itself
Interfacial tension, so that the oil containing aging ingredient is mutually dispersed in biphasic solvent in the form of micro- solidifying pearl
In, micro- solidifying pearl size controlling is in 1~2mm.Meanwhile aging ingredient is also added in dicyandiamide solution, formation is uniformly dispersed, stablizes
The good micro- solidifying anti-ageing Essence of pearl of property, preparation process is simple, and method is easy to operate, and product stability is good.
(2) Essence of micro- solidifying pearl form enables aging ingredient slowly to discharge in skin surface, is deeply infiltrated into
Keratoderma, while aging ingredient mutually and in water phase is added oily, so that Essence plays double-deck anti-ageing effect.When
The essence is applied to surface, is that the anti-ageing ingredient of oil droplet in essence discharges into skin first, secondly the anti-ageing ingredient in water phase
Skin is discharged into again, so that the nutritional ingredient in essence be made to achieve the effect that slow release.
(3) when hydrolecithin and other active components are combined, so that micro- solidifying pearl is more stable in water phase
Ground exists, while the penetration enhancing of entire component, nutritional ingredient are able to enter skin corium and preferably absorb.
(4) the puncture vine berry extract in micro- solidifying pearl essence contains peroxide catabolic enzyme, when with green colored grace Nan Fanqieshu
When bark extract and carnosine interact, so that the antioxidation of green colored grace south tomato bark extract and carnosine is increased
By force, to play apparent anti-aging effects, the anti-aging effects of Essence is made to reach best；Technical solution provided by the invention
Skin can be readily penetrated through, through dermal layer of the skin is penetrated deep into, plays and improves skin repair power of regeneration, reduces free radical
Damage, has the function that anti-aging；Meanwhile can inhibit the synthesis of SNARE assembly, inhibit the release of catecholamine, promotes glue
While former albumen generates, inhibit MMP and cytokine-expressing, protect collagen not to be degraded enzyme degradation, increase type i collagen
The synthesis of albumen, to reach crease-resistant and skin smoothing effect.
Specific embodiment
For the ease of the understanding of this technology personnel, the present invention is made further instructions below with reference to embodiment, is implemented
The content that mode refers to not is limitation of the invention.
Embodiment 1
A kind of micro- solidifying anti-ageing Essence of pearl, the raw material including following weight percent:
Embodiment 2
A kind of micro- solidifying anti-ageing Essence of pearl, the raw material including following weight percent:
Embodiment 3
A kind of micro- solidifying anti-ageing Essence of pearl, the raw material including following weight percent:
Embodiment 4
A kind of micro- solidifying anti-ageing Essence of pearl, the raw material including following weight percent:
Embodiment 5
A kind of micro- solidifying anti-ageing Essence of pearl, the raw material including following weight percent:
Embodiment 6
A kind of micro- solidifying anti-ageing Essence of pearl, the raw material including following weight percent:
The preparation method of any one solidifying anti-ageing Essence of pearl of Examples 1 to 6 is:
1) deionized water in A phase component is added in emulsion pot, stirring is warming up to 75-80 DEG C；
2) by B1 phase component mixing homogeneous 2-3min to no fine particle that is uniformly dispersed, B2 phase component, B3 phase component are added
Enter in B1 phase component, stirring is warming up to 70-75 DEG C to being dissolved as transparent oil-phase solution；
3) 75-80 DEG C of emulsion pot is kept, slowly oil-phase solution made from step 2) is added by mixing speed 80-120rpm
In the water phase of step 1), stirring to oil is mutually separated into fine particle, adds oily phase, and mixing speed 60-80rpm stirs 10-
15min is to forming uniform oil droplet particle；
4) steam valve for closing emulsion pot is opened and freezes water valve, unlatching rapid cooling, in temperature-fall period, mixing speed
100rpm is cooled to 35-45 DEG C, forms uniform oil droplet particle；
5) C1 phase, C4 phase, D phase component are added in emulsion pot, is stirred evenly, C2 component is added, improve mixing speed extremely
140-160rpm stirs 10-15min, and C3 component is added, and improves mixing speed to 180-200rpm, stirs 15-20min into
With it is complete, stir evenly, can discharge.
Comparative example 1
Component in embodiment 6 is prepared as follows:
1) A phase, C1 phase, C2 are mixed and is added in emulsion pot, stirring is warming up to 75-80 DEG C, is dissolved as uniform water phase
Solution；
2) B1 mixing homogenous disperse B2 phase, B3 phase is added in B1 phase with this, stirring is warming up to uniformly without fine particle
70-75 DEG C to being dissolved as transparent oil-phase solution；
3) oil-phase solution is added in aqueous phase solution, homogeneous, insulated and stirred cool down after twenty minutes after mixing evenly；
4) it is cooled to 40 DEG C, C3 phase is added, stirring adds C4 phase, D phase stirs evenly to neutralizing completely, can discharge.
Experimental example 1
Stability test
Experimental method: it is directed to Examples 1 to 6, the sample in comparative example 1 carries out illumination respectively, heat-resisting, cold-resistant, fever and chills are handed over
Stability test under fork, normal temperature condition.
1) illumination: the test sample of Examples 1 to 6, comparative example 1 is put at illumination, is observed sample the 0th, 1,2,4,8 week
Variation, if change.
Test result of 1 sample of table under illumination condition
Wherein, √ indicates that sample state is normal, × indicate sample state variation, similarly hereinafter.
As can be seen from the table, by 8 weeks, the Essence of Examples 1 to 6 is in stable condition under illumination condition, does not have
There is generating state variation.The sample layering of 1 method of comparative example preparation, state labile.
2) resist cold: by Examples 1 to 6, the test sample of comparative example 1 is placed in low-temperature test in -15 DEG C of incubators, observes sample
Product variation.
The cold-resistant test result of 2 sample of table
As can be seen from the table, by 8 weeks, the Essence of Examples 1 to 6 is in stable condition under the conditions of -15 DEG C, does not have
There is generating state variation, illustrates that its cold-resistant effect is good.The sample layering of 1 method of comparative example preparation, state labile.
3) heat-resisting: by Examples 1 to 6, the test sample of comparative example 1 is placed in high temperature test in 45 DEG C of incubators, observes sample
Product variation；
The heat-resisting test result of 3 sample of table
As can be seen from the table, by 8 weeks, the Essence of Examples 1 to 6 is in stable condition under the conditions of -45 DEG C, does not have
There is generating state variation, illustrates that its heat-resisting effect is good.The sample of 1 method of comparative example preparation is in stratification state, and system is unstable.
4) fever and chills intersect: by Examples 1 to 6, the test sample of comparative example 1 is in -15 DEG C/45 DEG C temperature alternating incubators
Fever and chills temperature cross-beta, 7 days circulation primaries recycle 8 periods, observe sample variation；
The fever and chills cross-beta result of 4 sample of table
As can be seen from the table, by 8 weeks, the Essence of Examples 1 to 6 shape under the conditions of -15 DEG C/45 DEG C of alternations
State is stablized, and there is no state change, the effect for illustrating that its resistance to fever and chills intersects is good.The sample of 1 method of comparative example preparation is in layering
State, system are unstable.
5) room temperature: the test sample of Examples 1 to 6, comparative example 1 is put in room temperature, observes sample variation；
The room temperature test result of 5 sample of table
As can be seen from the table, by 8 weeks, the Essence of Examples 1 to 6 is in stable condition under normal temperature conditions, does not have
There is generating state variation, illustrating it under normal temperature conditions has preferable stability.The sample of 1 method of comparative example preparation is in layering
State, and system is unstable.
Therefore, from the above test result can be seen that for Examples 1 to 6 sample carry out heat-resisting, cold-resistant, fever and chills intersect,
Illumination, room temperature are tested 8 weeks, and sample is without exception, illustrates that the stability of the product is good.Both the preparation of comparative example 1 by conventional method
The resulting Essence of method can be layered, state labile.
Experimental example 2
Skin elasticity test
1) experimental method: choosing average age is to have wrinkle, the undamaged female volunteers 40 of skin health in 40~45 years old
Name, male volunteers 20.6 groups are randomly divided into, every group 10, uses micro- solidifying anti-ageing essence of pearl in Examples 1 to 6 respectively
Liquid.Subject smears Essence in face, smears twice, is used continuously 4 weeks sooner or later daily.During experiment, subject is being tested
Position cannot smear any other cosmetics.
2) test apparatus
Skin elasticity instrument CotometerMPA580 host, Reviscometer RV600 elastic fibrous tissue test probe
(German CK company)
3) Flexibility Test Method: the skin of the 0th week and 4 weeks is tested respectively using skin elasticity instrument Cutometer MPA580
State, test position are cheekbone portion, and probe is averaged in same tested region duplicate measurements 3 times when measurement.Test parameter is R2
(the springback capacity Ua of skin and the ratio between maximum tension amount Uf when having a negative pressure) when no negative pressure, R2 closer to 1, get over by the elasticity of skin
It is good ,-the 0 week R2 value of R2 average change value=4th week R2 value, the R2 average rate of change=R2 average change value/0th week R2 value.Tool
The test result of body skin elasticity is as shown in table 6.
The variation of 6 skin elasticity R2 of table
| Sample | 0th week | 4th week | Average change value | The average rate of change (%) |
| Embodiment 1 | 0.532 | 0.656 | 0.124 | 23.31 |
| Embodiment 2 | 0.512 | 0.655 | 0.143 | 27.93 |
| Embodiment 3 | 0.523 | 0.675 | 0.152 | 29.06 |
| Embodiment 4 | 0.548 | 0.712 | 0.164 | 29.93 |
| Embodiment 5 | 0.604 | 0.796 | 0.192 | 31.79 |
| Embodiment 6 | 0.576 | 0.757 | 0.181 | 31.42 |
Table 6 is the situation of change using skin elasticity R2 behind Essence 4 weeks in Examples 1 to 6.Data can be with from table
Find out, after using the Essence in Examples 1 to 6 for a period of time, the elasticity of skin is improved.For embodiment
5, using after 4 weeks, skin elasticity R2 is mentioned to 30% or more embodiment 6, and it is good to illustrate that micro- solidifying anti-ageing Essence of pearl has
Anti-aging effects.
Experimental example 3
The test of dermatoglyph degree
1) experimental method: choosing average age is to have wrinkle, the undamaged female volunteers 30 of skin health in 40~45 years old
Name, male volunteers 12.6 groups are randomly divided into, every group 7, uses micro- solidifying anti-ageing Essence of pearl in Examples 1 to 6 respectively.
Subject smears Essence at inboard arm is away from 10 centimeters of palm base portion, smears twice, is used continuously 4 weeks sooner or later daily.It is real
During testing, subject cannot smear any other cosmetics in Test sites.
2) test apparatus
Skin image analysis system (SkinVisiometerSV600)
3) texture test method: the numerical value that the 0th week and 4 weeks statistics volunteer's Test sites measure analyzes its skin line
Reason degree situation of change.
The variation of 7 dermatoglyph degree of table
| Sample | 0th week | 4th week | Average change value | The average rate of change (%) |
| Embodiment 1 | 53.5 | 33.6 | -19.9 | -37.20 |
| Embodiment 2 | 54.3 | 33.0 | -21.3 | -39.23 |
| Embodiment 3 | 55.4 | 34.6 | -20.8 | -37.55 |
| Embodiment 4 | 53.1 | 32.5 | -20.6 | -38.80 |
| Embodiment 5 | 55.2 | 31.1 | -24.1 | -43.66 |
| Embodiment 6 | 54.7 | 31.2 | -23.5 | -42.90 |
As can be seen from Table 7, using after of the invention Essence 4 weeks, dermatoglyph situation is clearly better.Dermatoglyph degree
The average rate of change 37% or more.The average rate of change in embodiment 5, embodiment 6 is up to 40% or more.Illustrate tool of the present invention
There are good anti-aging effects；Since the product of comparative example preparation is in water-oil separating state, it is considered as substandard product, therefore does not carry out
Skin detection test.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (10)
1. a kind of micro- solidifying anti-ageing Essence of pearl, which is characterized in that by A phase component, B1 phase component, B2 phase component, B3 phase component, C1
Phase component, C2 phase component, C3 phase component, C4 phase component and D phase component composition, according to micro- solidifying anti-ageing Essence total weight percentage of pearl
Number meter, main component in each phase and its accounts for Essence total weight percentage composition are as follows:
A phase: appropriate amount of deionized water；
B1 phase: emollient 3~7%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.005-0.05%；
B2 phase: emollient 2~9%, antidotal agent 0.11~3%；
B3 phase: emollient 0.3~2%；
C1 phase: anti-inflammatory agent 0.02~0.6%, moisturizer 7.4~19.8%；
C2 phase: appropriate deionized water, suspending agent 0.1~0.5%；
C3 phase: appropriate deionized water, pH adjusting agent 0.01~0.14%；
C4 phase: antidotal agent 0.7~9.5%, skin conditioning agent 0.05~2%；
D phase: antidotal agent 0.01-1%.
2. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that further include assigning in the B2 phase
Pastil Roman chamomile caul-fat 0.001-0.05%.
3. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that emollient described in B1 phase is
Pentaerythrite four (thylhexoic acid) ester；Emollient described in B2 phase is one in docosyl alcohol and dimethyl silicone polymer, paraffin
Kind or two kinds any combination, antidotal agent are ubiquinone // tocopherol acetate //C12-15 alcohol benzoic ether // tocopheryl acetate
The combination of one or both of ester //C12-15 alcohol benzoic ether or dipalmitoyl hydroxyproline；Moisturizing described in B3 phase
Agent is Parleam.
4. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that moisturizer described in C1 phase is
One of dipropylene glycol, glycerol, 1,3- propylene glycol, 1,2- hexylene glycol or any combination；Anti-inflammatory agent described in C1 phase is urine
One of Bursin or dipotassium glycyrrhizinate or combination.
5. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that the C1 phase further includes chelating
Agent EDETATE SODIUM 0.01~0.15%, antioxidant parahydroxyacet-ophenone 0.4~0.8%.
6. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that suspending agent described in C2 phase is
Carbomer；PH adjusting agent described in C3 phase is sodium hydroxide；Antidotal agent described in C4 phase is Argireline, palm
One kind or any combination of acyl tripeptides -5, decarboxylation carnosine HCl, the skin conditioning agent are golden yellow camomile extract.
7. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that the D phase further includes moisturizing
Agent 0.1-2%, and moisturizer is aloe barbadensis Miller leaf extract, kuh-seng root extract, lycium barbarum berry extract, purple coneflower
Extract, the composition of HERBA DENDROBII stem extraction or the combination with hydrolecithin.
8. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 1, which is characterized in that antidotal agent in the D phase
For carnosine.
9. the micro- solidifying anti-ageing Essence of pearl of one kind according to claim 8, it is characterised in that antidotal agent also wraps in the D phase
Include one of puncture vine berry extract or green colored grace south tomato bark extract or combination.
10. the method for preparing the micro- solidifying anti-ageing Essence of pearl of one kind described in claim 1, which is characterized in that mainly include following
Step:
1) deionized water in A phase component is added in emulsion pot, stirring is warming up to 75-80 DEG C；
2) by B1 phase component mixing homogeneous 2-3min to no fine particle that is uniformly dispersed, B1 is added in B2 phase component, B3 phase component
In phase component, stirring is warming up to 70-75 DEG C to being dissolved as transparent oil-phase solution；
3) 75-80 DEG C of emulsion pot, mixing speed 80-120rpm is kept, step slowly is added in oil-phase solution made from step 2)
1) in water phase, stirring to oil is mutually separated into fine particle, adds oily phase, mixing speed 60-80rpm, stirring 10-15min is extremely
Form uniform oil droplet particle；
4) steam valve for closing emulsion pot is opened and freezes water valve, unlatching rapid cooling, in temperature-fall period, mixing speed 100rpm,
It is cooled to 35-45 DEG C, forms uniform oil droplet particle；
5) C1 phase, C4 phase, D phase component are added in emulsion pot, is stirred evenly, C2 component is added, improve mixing speed to 140-
160rpm stirs 10-15min, and C3 component is added, and improves mixing speed to 180-200rpm, stirs 15-20min to having neutralized
Entirely, it stirs evenly, can discharge.
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| CN117224433A (en) * | 2023-09-27 | 2023-12-15 | 铂臻(广州)生物科技有限公司 | Suspended oil-pearl essence and preparation method thereof |
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