CN109010781A - A kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof - Google Patents

A kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof Download PDF

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Publication number
CN109010781A
CN109010781A CN201811210344.XA CN201811210344A CN109010781A CN 109010781 A CN109010781 A CN 109010781A CN 201811210344 A CN201811210344 A CN 201811210344A CN 109010781 A CN109010781 A CN 109010781A
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parts
essential oil
radix
removing stasis
activating microcirculation
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韦水秀
韦昌铠
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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Abstract

The invention discloses a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, the wherein composition of the raw material of essential oil by weight are as follows: 10-28 parts of lopseed, 7-20 parts of the root of Chinese clematis, 5-20 parts of Radix Angelicae Pubescentis, 5-13 parts of rhizoma ligustici, 4-20 parts of Rhizoma Et Radix Notopterygii, 4-13 parts of radix saposhnikoviae, 7-20 parts of ginseng, 4-16 parts of Radix Astragali, 5-15 parts of Rhizoma Chuanxiong, 4-19 parts of safflower, 5-18 parts of Cortex Eucommiae, 4-15 parts of cynomorium songaricum, 5-18 parts of sweet wormwood, 6-19 parts of cortex cinnamomi, 5-15 parts of ginger, 3-8 parts of Radix Glycyrrhizae.Preparation method of the present invention is simple, significant in efficacy.The made essential oil of the present invention has no toxic side effect, low in cost, easy to use；Qi-regulating, activating microcirculation and removing stasis medicinal are relieved pain for affected part, quick acting can be treated for various diseases.

Description

A kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof
Technical field
The present invention relates to essential oil of traditional Chinese medicine technical field, more particularly to a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and Preparation method.
Background technique
Essential oil is the volatile flavor that extraction is refined in the flower from plant, leaf, stem, root or fruit, volatility compared with By force.Essential oil is generally divided into folk prescription essential oil and compound essential oil, and compound essential oil refers to that several folk prescription essential oils have matched, can make immediately Formula essential oil.By researching and developing the characteristic and effect of various raw materials, is deployed by combination and determine formula, finished product is made.For The compound essential oil that skin surface is smeared is also a variety of folk prescription essential oils and the mixture of compound essential oil by a certain percentage.
Hemostasis is the pathological product formed in lysis, and is the pathogenic factor of certain diseases.All blood circulating out of vessels accumulate In vivo or hematogenous blockage, block in the blood in passages through which vital energy circulates and internal organs, referred to as hemostasis.Its Crack cause has the deficiency of vital energy, the stagnation of the circulation of vital energy, blood Cold, blood-head can make hematogenous blockage, and form hemostasis.Various trauma skin and internal organ, make blood circulating out of vessels accumulate in vivo and Form hemostasis.After hemostasis is formed, stops product and do not dissipate in vivo, not only lose blood supports effect, but also can lead to new lesion Occur.
Promoting blood circulation and stopping pain stagnation resolvation is the drug therapy pain card and the stasis of blood that has dissipation analgesic effect or can attack by internal hemostasis The method of blood disease.General promoting blood circulation and stopping pain stagnation resolvation drug plays the role of that unobstructed blood vessels, the dissipation stasis of blood be stagnant, menstruction regulating and pain relieving.Currently, often The promoting blood circulation and stopping pain stagnation resolvation drug seen is divided into oral and is applied with two kinds, and specific aim is not strong, slow effect, it is difficult to dispel comprehensively pain and Hemostasis, and toxic side effect is larger.
Therefore, in conjunction with the above problem, one kind is provided and is had no toxic side effect, quick acting has analgesic qi-regulating, activating microcirculation and removing stasis medicinal function The problem of plants herb essential oil of effect is those skilled in the art's urgent need to resolve.
Summary of the invention
In view of this, the present invention provides a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, this method preparation Essential oil have no toxic side effect, it is low in cost, it is easy to use, for affected part relieve pain qi-regulating, activating microcirculation and removing stasis medicinal, quick acting.
A kind of activating microcirculation and removing stasis medicinal plants herb essential oil, the composition of raw material by weight are as follows: 10-28 parts of lopseed, root of Chinese clematis 7- 20 parts, 5-20 parts of Radix Angelicae Pubescentis, 5-13 parts of rhizoma ligustici, 4-20 parts of Rhizoma Et Radix Notopterygii, 4-13 parts of radix saposhnikoviae, 7-20 parts of ginseng, 4-16 parts of Radix Astragali, Rhizoma Chuanxiong 5- 15 parts, 4-19 parts of safflower, 5-18 parts of Cortex Eucommiae, 4-15 parts of cynomorium songaricum, 5-18 parts of sweet wormwood, 6-19 parts of cortex cinnamomi, 5-15 parts of ginger, Radix Glycyrrhizae 3- 8 parts.
Preferably, the composition of the raw material of the activating microcirculation and removing stasis medicinal plants herb essential oil by weight are as follows: 15-25 parts of lopseed, 12-18 parts of the root of Chinese clematis, 6-15 parts of Radix Angelicae Pubescentis, 7-10 parts of rhizoma ligustici, 5-17 parts of Rhizoma Et Radix Notopterygii, 6-10 parts of radix saposhnikoviae, 9-18 parts of ginseng, Radix Astragali 5-12 Part, 5-10 parts of Rhizoma Chuanxiong, 6-15 parts of safflower, 7-14 parts of Cortex Eucommiae, 6-11 parts of cynomorium songaricum, 8-15 parts of sweet wormwood, 6-13 parts of cortex cinnamomi, ginger 7-12 Part, 4-5 parts of Radix Glycyrrhizae.
Preferably, the composition of the raw material of the activating microcirculation and removing stasis medicinal plants herb essential oil by weight are as follows: 20 parts of lopseed, Wheeling 18 parts celestial, 13 parts of Radix Angelicae Pubescentis, 9 parts of rhizoma ligustici, 15 parts of Rhizoma Et Radix Notopterygii, windproof 7 parts, 15 parts of ginseng, 10 parts of Radix Astragali, 9 parts of Rhizoma Chuanxiong, safflower 13 Part, 10 parts of Cortex Eucommiae, 8 parts of cynomorium songaricum, 9 parts of sweet wormwood, 10 parts of cortex cinnamomi, 9 parts of ginger, 4 parts of Radix Glycyrrhizae.
To achieve the goals above, The technical solution adopted by the invention is as follows:
A kind of activating microcirculation and removing stasis medicinal plants herb essential oil, specific step is as follows for its preparation method:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, sieving；
S2, infiltration: the raw material after S1 is sieved is placed in container, inserts the organic solution of raw material gross weight 50-150%, leaching Moisten 2-4min, takes the raw material of wetting；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, to container plus Pressure, container inner pressure 20-25MPa, temperature are 42-50 DEG C, gaseous state CO2Become liquid, the plants essential oil of raw material is dissolved in CO2Liquid It in body, is depressurized after 2-5h, liquid CO2It is vaporized into gaseous state, isolates essential oil, separation temperature is 50-60 DEG C, and collection obtains plant plait This essential oil.
As can be seen from the above technical solutions, compared with prior art, beneficial effects of the present invention are as follows:
Plants herb essential oil is prepared in technical solution of the present invention using supercritical CO2Fluids extraction, can be close to room Temperature temperature under the conditions of and CO2It is extracted under gas blanket, effectively prevents the oxidation and loss of heat-sensitive substance.Cause This, remains the whole components of medicinal plant, and higher boiling, low volatility, the substance being easily pyrolyzed can be existed in extract It is extracted below its boiling temperature.Promoting blood circulation and stopping pain stagnation resolvation plants herb essential oil prepared by the present invention has the promoting blood circulation of highly significant Stagnation resolvation, regulating qi-flowing for relieving pain effect, it is cheap, it is easy to use, have tonifying Qi, blood-nourishing, warming channel and expelling cold, heat-clearing, promoting the circulation of qi, capture Effect can treat various diseases simultaneously.
Preferably, it pulverizes and sieves to obtain the coarse powder of 10-20 mesh in the step S1.
Preferably, organic solvent is any one or two kinds in ethyl alcohol, ethyl acetate and hexamethylene in the step S2 The solvent mixed above.
Preferably, the step S3 is passed through CO2Flow is 18kg/h.
Preferably, the container internal pressure after the step S3 decompression is 4.5-5.5MPa.
Preferably, the activating microcirculation and removing stasis medicinal plants herb essential oil is applied to the external application of skin surface.
Preferably, the activating microcirculation and removing stasis medicinal plants herb essential oil molecule is nano molecular.
In conclusion technical solution disclosed by the invention ensure that made plants herb essential oil for trauma flesh Skin, internal organ, which make blood circulating out of vessels accumulate the hemostasis formed in vivo, to be had effects that eliminate pain comprehensively and stops silt, rapid-action, energy and When eliminate hemostasis, avoid extravasated blood stop product in vivo dissipate cause new lesion to occur.And the raw materials used in the present invention is pure natural Plants herb extracts high-quality activating microcirculation and removing stasis medicinal plants herb essence oil nanometer molecule by scientific matching, is coated on sufferer skin table Layer gos deep into the through lesion of skin, has no toxic side effect and significant in efficacy.The activating microcirculation and removing stasis medicinal plants herb essential oil of preparation can be extensive It is extended to market, meets people's health demand.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects It encloses.
Embodiment 1:
The embodiment of the present invention 1 discloses a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, the technical side of use Case is as follows:
A kind of activating microcirculation and removing stasis medicinal plants herb essential oil, the composition of raw material by weight are as follows: 10 parts of lopseed, 7 parts of the root of Chinese clematis, solely 20 parts living, 13 parts of rhizoma ligustici, 4 parts of Rhizoma Et Radix Notopterygii, 4 parts of radix saposhnikoviae, 20 parts of ginseng, 16 parts of Radix Astragali, 5 parts of Rhizoma Chuanxiong, 4 parts of safflower, 18 parts of Cortex Eucommiae, 15 parts of cynomorium songaricum, 5 parts of sweet wormwood, 6 parts of cortex cinnamomi, 15 parts of ginger, 8 parts of Radix Glycyrrhizae.
The activating microcirculation and removing stasis medicinal plants herb essential oil, specific step is as follows for its preparation method:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, cross 10 meshes；
S2, infiltration: the raw material after S1 is sieved is placed in container, inserts the organic solution of raw material gross weight 50%, infiltration 2min, takes the raw material of wetting, and organic solvent is that any one or two kinds or more in ethyl alcohol, ethyl acetate and hexamethylene mix Solvent；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, it is passed through CO2 Flow is 18kg/h, is pressurizeed to container, container inner pressure 20MPa, and temperature is 42 DEG C, gaseous state CO2Become liquid, the plant of raw material Object essential oil is dissolved in CO2It in liquid, is depressurized after 2h, the container internal pressure after decompression is 4.5MPa, liquid CO2It is vaporized into gaseous state, point Essential oil is separated out, separation temperature is 50 DEG C, collects and obtains being applied to the plants herb essential oil that skin surface is applied with.
Embodiment 2:
The embodiment of the present invention 2 discloses a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, the technical side of use Case is as follows:
A kind of activating microcirculation and removing stasis medicinal plants herb essential oil, the composition of raw material by weight are as follows: 15 parts of lopseed, 12 parts of the root of Chinese clematis, 15 parts of Radix Angelicae Pubescentis, 10 parts of rhizoma ligustici, 5 parts of Rhizoma Et Radix Notopterygii, windproof 6 parts, 18 parts of ginseng, 12 parts of Radix Astragali, 5 parts of Rhizoma Chuanxiong, 6 parts of safflower, Cortex Eucommiae 14 Part, 11 parts of cynomorium songaricum, 8 parts of sweet wormwood, 6 parts of cortex cinnamomi, 12 parts of ginger, 5 parts of Radix Glycyrrhizae.
The activating microcirculation and removing stasis medicinal plants herb essential oil, specific step is as follows for its preparation method:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, cross 12 meshes；
S2, infiltration: the raw material after S1 is sieved is placed in container, inserts the organic solution of raw material gross weight 70%, infiltration 2min, takes the raw material of wetting, and organic solvent is that any one or two kinds or more in ethyl alcohol, ethyl acetate and hexamethylene mix Solvent；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, it is passed through CO2 Flow is 18kg/h, is pressurizeed to container, container inner pressure 21MPa, and temperature is 44 DEG C, gaseous state CO2Become liquid, the plant of raw material Object essential oil is dissolved in CO2It in liquid, is depressurized after 4h, the container internal pressure after decompression is 4.8MPa, liquid CO2It is vaporized into gaseous state, point Essential oil is separated out, separation temperature is 52 DEG C, collects and obtains being applied to the plants herb essential oil that skin surface is applied with.
Embodiment 3:
The embodiment of the present invention 3 discloses a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, the technical side of use Case is as follows:
20 parts of lopseed, 18 parts of the root of Chinese clematis, 13 parts of Radix Angelicae Pubescentis, 9 parts of rhizoma ligustici, 15 parts of Rhizoma Et Radix Notopterygii, windproof 7 parts, 15 parts of ginseng, Radix Astragali 10 parts, 9 parts of Rhizoma Chuanxiong, 13 parts of safflower, 10 parts of Cortex Eucommiae, 8 parts of cynomorium songaricum, 9 parts of sweet wormwood, 10 parts of cortex cinnamomi, 9 parts of ginger, 4 parts of Radix Glycyrrhizae.
The activating microcirculation and removing stasis medicinal plants herb essential oil, specific step is as follows for its preparation method:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, cross 14 meshes；
S2, infiltration: the raw material after S1 is sieved is placed in container, and filling raw material infiltrates 3min, take with the organic solution of weight The raw material of wetting, organic solvent are any one or two kinds or more mixed solvents in ethyl alcohol, ethyl acetate and hexamethylene；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, it is passed through CO2 Flow is 18kg/h, is pressurizeed to container, container inner pressure 22MPa, and temperature is 46 DEG C, gaseous state CO2Become liquid, the plant of raw material Object essential oil is dissolved in CO2It in liquid, is depressurized after 5h, the container internal pressure after decompression is 5.0MPa, liquid CO2It is vaporized into gaseous state, point Essential oil is separated out, separation temperature is 55 DEG C, collects and obtains being applied to the plants herb essential oil that skin surface is applied with.
Embodiment 4:
The embodiment of the present invention 4 discloses a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, the technical side of use Case is as follows:
A kind of activating microcirculation and removing stasis medicinal plants herb essential oil, the composition of raw material by weight are as follows: 25 parts of lopseed, 18 parts of the root of Chinese clematis, 6 parts of Radix Angelicae Pubescentis, 7 parts of rhizoma ligustici, 17 parts of Rhizoma Et Radix Notopterygii, windproof 10 parts, 9 parts of ginseng, 5 parts of Radix Astragali, 10 parts of Rhizoma Chuanxiong, 15 parts of safflower, Cortex Eucommiae 7 Part, 6 parts of cynomorium songaricum, 15 parts of sweet wormwood, 13 parts of cortex cinnamomi, 7 parts of ginger, 4 parts of Radix Glycyrrhizae.
The activating microcirculation and removing stasis medicinal plants herb essential oil, specific step is as follows for its preparation method:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, cross 16 meshes；
S2, infiltration: the raw material after S1 is sieved is placed in container, inserts the organic solution of raw material gross weight 120%, infiltration 4min, takes the raw material of wetting, and organic solvent is that any one or two kinds or more in ethyl alcohol, ethyl acetate and hexamethylene mix Solvent；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, it is passed through CO2 Flow is 18kg/h, is pressurizeed to container, container inner pressure 23MPa, and temperature is 48 DEG C, gaseous state CO2Become liquid, the plant of raw material Object essential oil is dissolved in CO2It in liquid, is depressurized after 4h, the container internal pressure after decompression is 5.2MPa, liquid CO2It is vaporized into gaseous state, point Essential oil is separated out, separation temperature is 58 DEG C, collects and obtains being applied to the plants herb essential oil that skin surface is applied with.
Embodiment 5:
The embodiment of the present invention 5 discloses a kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof, the technical side of use Case is as follows:
A kind of activating microcirculation and removing stasis medicinal plants herb essential oil, the composition of raw material by weight are as follows: 28 parts of lopseed, 20 parts of the root of Chinese clematis, 5 parts of Radix Angelicae Pubescentis, 5 parts of rhizoma ligustici, 20 parts of Rhizoma Et Radix Notopterygii, windproof 13 parts, 7 parts of ginseng, 4 parts of Radix Astragali, 15 parts of Rhizoma Chuanxiong, 19 parts of safflower, Cortex Eucommiae 5 Part, 4 parts of cynomorium songaricum, 18 parts of sweet wormwood, 19 parts of cortex cinnamomi, 5 parts of ginger, 3 parts of Radix Glycyrrhizae.
The activating microcirculation and removing stasis medicinal plants herb essential oil, specific step is as follows for its preparation method:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, cross 20 meshes；
S2, infiltration: the raw material after S1 is sieved is placed in container, inserts the organic solution of raw material gross weight 150%, infiltration 4min, takes the raw material of wetting, and organic solvent is that any one or two kinds or more in ethyl alcohol, ethyl acetate and hexamethylene mix Solvent；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, it is passed through CO2 Flow is 18kg/h, is pressurizeed to container, container inner pressure 25MPa, and temperature is 50 DEG C, gaseous state CO2Become liquid, the plant of raw material Object essential oil is dissolved in CO2It in liquid, is depressurized after 5h, the container internal pressure after decompression is 5.5MPa, liquid CO2It is vaporized into gaseous state, point Essential oil is separated out, separation temperature is 60 DEG C, collects and obtains being applied to the plants herb essential oil that skin surface is applied with.
In order to further prove the activating microcirculation and removing stasis medicinal health-care efficacy of essential oil in product of the present invention, to 1-5 system of the embodiment of the present invention Standby plants herb essential oil out is tested.
Healthy rat is chosen, is randomly divided into 7 groups, every group has 10 mouse, and 1-5 group respectively corresponds 5 embodiment groups, and the 6th Group is ointment group, and the ointment of selection is the common stagnation resolvation ointment in market, and dosage is consistent with the essential oil amount that 1-5 group uses；7th group is sky White control group.1-7 group takes blood 0.1ml from tail vein under sterile working, and it is left that the new blood of taking-up injects blood sampling rat immediately Hemotoncus is caused in vola pedis bottom afterwards.Corresponding drug is given after injection immediately.The left back foot of rat after 4h is administered in measurement respectively Sufficient volume, administration process holding essential oil, ointment directly contact the skin of rat.
This experiment the results show that administration 4h after, smear essential oil, the affected part for sticking ointment 1-6 group sufficient volume obviously increase Greatly, the 7th group of sufficient volume has the tendency that continuing to increase, this may be to cause local organization acute inflammation to cause by injecting self blood , for rear 1-5 group without apparent difference, sufficient volume is close, illustrates that acute inflammatory reaction is eased for 24 hours.The 1-6 group phase of administration group Than the 7th group local patholoic change mitigates, although and the 6th group of local patholoic change sticking ointment mitigates, without the bright of 1-5 group mitigation It is aobvious.The stagnation resolvation ointment common on the market that this explanation is selected in an experiment has some improvement to self hemotoncus model tool, But its curative effect is weaker than the essential oil for smearing preparation of the embodiment of the present invention.The experimental results showed that plants herb essential oil tool prepared by the present invention There are the function of promoting blood circulation to disperse blood clots of quick acting, and the stagnation resolvation ointment that therapeutic effect is common better than market.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other The difference of embodiment, the same or similar parts in each embodiment may refer to each other.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (10)

1. a kind of activating microcirculation and removing stasis medicinal plants herb essential oil, which is characterized in that the raw material of the activating microcirculation and removing stasis medicinal plants herb essential oil is by weight Measure the composition of part are as follows: 10-28 parts of lopseed, 7-20 parts of the root of Chinese clematis, 5-20 parts of Radix Angelicae Pubescentis, 5-13 parts of rhizoma ligustici, 4-20 parts of Rhizoma Et Radix Notopterygii, radix saposhnikoviae 4-13 parts, 7-20 parts of ginseng, 4-16 parts of Radix Astragali, 5-15 parts of Rhizoma Chuanxiong, 4-19 parts of safflower, 5-18 parts of Cortex Eucommiae, 4-15 parts of cynomorium songaricum, blueness 5-18 parts of wormwood artemisia, 6-19 parts of cortex cinnamomi, 5-15 parts of ginger, 3-8 parts of Radix Glycyrrhizae.
2. a kind of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 1, which is characterized in that the activating microcirculation and removing stasis medicinal plant The composition of the raw material of essential oils of herbs by weight are as follows: 15-25 parts of lopseed, 12-18 parts of the root of Chinese clematis, 6-15 parts of Radix Angelicae Pubescentis, rhizoma ligustici 7- 10 parts, 5-17 parts of Rhizoma Et Radix Notopterygii, 6-10 parts of radix saposhnikoviae, 9-18 parts of ginseng, 5-12 parts of Radix Astragali, 5-10 parts of Rhizoma Chuanxiong, 6-15 parts of safflower, Cortex Eucommiae 7-14 parts, 6-11 parts of cynomorium songaricum, 8-15 parts of sweet wormwood, 6-13 parts of cortex cinnamomi, 7-12 parts of ginger, 4-5 parts of Radix Glycyrrhizae.
3. a kind of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 1, which is characterized in that the activating microcirculation and removing stasis medicinal plant The composition of the raw material of essential oils of herbs by weight are as follows: 20 parts of lopseed, 18 parts of the root of Chinese clematis, 13 parts of Radix Angelicae Pubescentis, 9 parts of rhizoma ligustici, Rhizoma Et Radix Notopterygii 15 Part, windproof 7 parts, 15 parts of ginseng, 10 parts of Radix Astragali, 9 parts of Rhizoma Chuanxiong, 13 parts of safflower, 10 parts of Cortex Eucommiae, 8 parts of cynomorium songaricum, 9 parts of sweet wormwood, cortex cinnamomi 10 parts, 9 parts of ginger, 4 parts of Radix Glycyrrhizae.
4. a kind of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 1, which is characterized in that the activating microcirculation and removing stasis medicinal plant Specific step is as follows for the preparation method of essential oils of herbs:
S1, raw material weighing: according to the parts by weight in formula weigh lopseed, the root of Chinese clematis, Radix Angelicae Pubescentis, rhizoma ligustici, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, ginseng, Radix Astragali, Rhizoma Chuanxiong, safflower, Cortex Eucommiae, cynomorium songaricum, sweet wormwood, cortex cinnamomi, ginger, Radix Glycyrrhizae, raw material mixed powder is broken, sieving；
S2, infiltration: the raw material after S1 is sieved is placed in container, inserts the organic solution of raw material gross weight 50-150%, infiltrates 2- 4min takes the raw material of wetting；
S3, supercritical CO2Fluid extraction: it takes the raw material of wetting to be placed in sealing container, CO is passed through into container2, it pressurizes to container, Container inner pressure is 20-25MPa, and temperature is 42-50 DEG C, gaseous state CO2Become liquid, the plants essential oil of raw material is dissolved in CO2Liquid In, it is depressurized after 2-5h, liquid CO2It is vaporized into gaseous state, isolates essential oil, separation temperature is 50-60 DEG C, and collection obtains plants herb Essential oil.
5. a kind of preparation method of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 4, which is characterized in that the step It pulverizes and sieves to obtain the coarse powder of 10-20 mesh in rapid S1.
6. a kind of preparation method of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 4, which is characterized in that the step Organic solvent is any one in ethyl alcohol, ethyl acetate and hexamethylene or two kinds or more mixed solvents in rapid S2.
7. a kind of preparation method of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 4, which is characterized in that the step Rapid S3 is passed through CO2Flow is 18kg/h.
8. a kind of preparation method of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 4, which is characterized in that the step Container internal pressure after rapid S3 decompression is 4.5-5.5MPa.
9. a kind of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 1-7, which is characterized in that the promoting blood circulation Stagnation resolvation plants herb essential oil is applied to the external application of skin surface.
10. a kind of activating microcirculation and removing stasis medicinal plants herb essential oil according to claim 9, which is characterized in that the activating microcirculation and removing stasis medicinal is planted Object essential oils of herbs molecule is nano molecular.
CN201811210344.XA 2018-10-17 2018-10-17 A kind of activating microcirculation and removing stasis medicinal plants herb essential oil and preparation method thereof Pending CN109010781A (en)

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Application publication date: 20181218