CN108294041A - A kind of bactericidal composition containing three octyl benzene sulfonate and benzothiostrobin of biguanides - Google Patents
A kind of bactericidal composition containing three octyl benzene sulfonate and benzothiostrobin of biguanides Download PDFInfo
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- CN108294041A CN108294041A CN201810279720.4A CN201810279720A CN108294041A CN 108294041 A CN108294041 A CN 108294041A CN 201810279720 A CN201810279720 A CN 201810279720A CN 108294041 A CN108294041 A CN 108294041A
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- Prior art keywords
- biguanides
- benzene sulfonate
- benzothiostrobin
- octyl benzene
- bactericidal composition
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of bactericidal compositions containing three octyl benzene sulfonate and benzothiostrobin of biguanides, it is characterised in that：It is compounded by three octyl benzene sulfonate of active ingredient biguanides and benzothiostrobin, and the weight ratio of three octyl benzene sulfonate of biguanides and benzothiostrobin is 1:60‑60:1；Being applied in combination for two kinds of fungicide, expands fungicidal spectrum, can prevent multiple diseases simultaneously；Notable synergistic effect is shown as to rice sheath blight disease；To Target crops, people and animals, Environmental security；It reduces formulation rate, reduce application times, be easy to use, reduce use cost, have the advantages that efficient, quick-acting, lasting period length.
Description
Technical field
The invention belongs to technical field of pesticide, particularly relate to a kind of containing three octyl benzene sulfonate of biguanides and benzene thiophene
The bactericidal composition of bacterium ester.
Background technology
It in agricultural production process, is lost caused by fungal disease to reduce, chemical prevention is more aobvious at present
One of means of work, but since for a long time, Scientific Usage of Drugs means do not have resulted in many diseases for unicity, continuity, repeatability etc.
Opportunistic pathogen generates currently used medicament different degrees of resistance, and it is reported that due to this unscientific medication means, various
The resistance generation time of medicament shortens year by year, and cost accounting, Environmental costs, medicament R＆D costs is caused to be significantly increased.It is based on
This present situation improves effect of drugs relatively inexpensive effective means in order to solve the above problem on the basis of existing.
Benzothiostrobin has broad spectrum antibacterial activity, in addition to having good preventive effect to cucumber downy mildew and powdery mildew, to black star
Black disease, charcoal Ju diseases, brown spot, gray mold, banded sclerotial blight, false smut, rubber point germ, banana sigatoka leaf spot disease, rubber spore
Tikka, rubber Pcriconia leaf spot bacterium, banana blight, sclerotinia sclerotiorum, citrus blossom-end rot etc. show excellent inhibition
Activity.And it is effective to the bacterial strain for generating resistance, have the characteristics that efficient, less toxic, environmental-friendly.
Three octyl benzene sulfonate of biguanides, chemical name：1,1- octyl methylene biguanides, three octyl phenylbenzimidazole sulfonic acid salt.It is double
Three octyl benzene sulfonate of guanidine is wide spectrum low toxicity fungicide, inhibits germ quasi-grease compound biosynthesis, and local permeability is strong,
There is very high growth inhibitory activity to pathogen sac fungus, Fungi Imperfecti.
There is no the relevant reports of three octyl benzene sulfonate of biguanides and benzothiostrobin compounding in the prior art.
Invention content
In order to overcome dosing existing for above-mentioned single bactericide big, environmental pollution is serious, germ resistance generates speed
Spend the shortcomings of fast, the present invention be directed to germ drug resistance the problem of, the medication of controlling plant diseases is improved, a kind of energy is provided
Enough delay the bactericidal composition of drug resistance.
Technical solution provided by the invention is：
A kind of bactericidal composition containing three octyl benzene sulfonate and benzothiostrobin of biguanides, it is pungent by active ingredient biguanides three
Alkylbenzene sulfonate and benzothiostrobin compound.
Preferably, the weight ratio of the three octyl benzene sulfonate of biguanides and benzothiostrobin is 1:60-60:1.As
It is preferred that the weight ratio of the three octyl benzene sulfonate of biguanides and benzothiostrobin is 1:1-1:40.
The present invention also provides it is a kind of include the bactericidal composition, the three octyl benzene sulfonate of biguanides and
The weight of benzothiostrobin accounts for the 10-50% of pesticidal preparations total weight, and surplus is auxiliary element pesticide-acceptable.
Preferably, the weight of the three octyl benzene sulfonate of biguanides and benzothiostrobin accounts for pesticidal preparations total weight
20-40%, surplus are auxiliary element auxiliary agent, solvent or filler pesticide-acceptable.
Preferably, the dosage form of the pesticidal preparations is wettable powder, water dispersible granules, suspending agent, microcapsule suspension
Agent, granule or aqueous emulsion etc..
The auxiliary agent used in the pesticidal preparations of the present invention includes solvent, dispersant, emulsifier, stabilizer, antifreezing agent, film forming
Agent, wetting agent etc. and it is other be beneficial to active ingredient in the formulation stablize and drug effect play known substance, be all pesticidal preparations
In commonly use or allow the various composition used, be not particularly limited, specific ingredient and dosage are according to recipe requirements by simply trying
Test determination.
The bactericidal composition of the present invention is applied in the multiple diseases on prevention crop, is particularly suitable for prevention rice banded sclerotial blight
Disease.The composition of the present invention can also be applied by common method, and such as spraying is spread, and amount of application is with weather condition or crop shape
State changes.
Compared with prior art, the present invention has the advantages that：
Being applied in combination for two kinds of fungicide, expands fungicidal spectrum, can prevent multiple diseases simultaneously；Rice sheath blight disease is showed
For notable synergistic effect；To Target crops, people and animals, Environmental security；It reduces formulation rate, reduce application times, be easy to use, reduce
Use cost has the advantages that efficient, quick-acting, lasting period length.
Specific implementation mode
The specific implementation mode of the present invention is described in detail with reference to embodiment, it is to be understood that the guarantor of the present invention
Shield range is not restricted by specific implementation.
Example of formulations
Embodiment 1：18% biguanides, three octyl benzene sulfonate benzothiostrobin wettable powder
By biguanides three octyl benzene sulfonate 9g, benzothiostrobin 9g, neopelex 13g, di-2-ethylhexylphosphine oxide naphthalene sulphur
Sour sodium 6g, wetting and penetrating agent F 3g, White Carbon black add to 100g, and mixture carries out air-flow crushing, and wettable powder is made.
Embodiment 2：25% biguanides, three octyl benzene sulfonate benzothiostrobin aqueous suspension agent
By biguanides three octyl benzene sulfonate 5g, benzothiostrobin 20g, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5g, base phenol formaldehyde
Resin polyoxyethylene ether 2g, glycerine 3g, silicone oil 0.5g, fatty alcohol polyoxyethyl ether 5.5g, xanthans 1g, bentonite 2g, water
100g is supplied, mixes, is homogenized through wet grinding, aqueous suspension agent is made.
Embodiment 3：30% biguanides, three octyl benzene sulfonate benzothiostrobin water dispersible granules
By biguanides three octyl benzene sulfonate 20g, benzothiostrobin 10g, alkyl benzene sulfonate calcium salt 6g, Nonyl pheno
Ether 6g, urea 2g, sodium bicarbonate 3g, bentonite 12g, kaolin add to 100, and water dispersible grain is made through crushing to be granulated in mixing
Agent.
Biological activity determination
Inventor has found three octyl benzene sulfonate of biguanides and benzothiostrobin compounded combination pair by a large amount of screening test
Rice sheath blight disease has significantly synergistic function, and rather than just the simple addition of two kinds of medicaments, this is from following biometric
Determine example to be clear that.
Bioassay example 1：Three octyl benzene sulfonate of biguanides compounds the interior to Rhizoctonia solani Kuhn with benzothiostrobin
Toxicity test
Subjects：Pick up from the Rhizoctonia solani Kuhn in field
Test method：Detached Vicia faba Leaves method.By Rhizoctonia solani Kuhn PDA culture medium culture, wait for that bacterium colony has just covered with training
When supporting ware, the card punch for being 5mm with internal diameter is punched from edge, and the mycelia block broken into is used as inoculum.Choose the consistent silkworm in leaf position
Beans blade often handles 10, is immersed in 10min in prepared liquid, and taking-up is dried, and is put into the culture dish for being covered with moisture retention paper,
5 concentration gradients are arranged in each medicament.Mycelia block is finally inverted in central vane, and is cultivated in 28 DEG C of constant incubators,
After the onset of waiting for control fully, lesion diameter is measured with crossing method, and calculate control effect.
Control effect is converted into niqueMin (y), liquor strength (μ g/ml) is converted into logarithm (x), with least square method
Concentration EC50 in calculating virulence equation and inhibiting, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to Sun Yunpei's Method.
When CTC≤80, then composition shows as antagonism, and as 80 ＜ CTC ＜ 120, then composition shows as being added and make
With when CTC >=120, then composition shows as synergistic effect.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) × 100
Percentage composition+B the medicament toxicity index of A in theoretical toxicity index (TTI)=A medicament toxicity index × mixture × mixed
The percentage composition of B in agent
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] × 100.
2 biguanides of table, three octyl benzene sulfonate compounds the indoor virulence to Rhizoctonia solani Kuhn with benzothiostrobin
Measurement result
As shown in table 2, in bactericidal composition of the invention biguanides three octyl benzene sulfonate and benzothiostrobin weight ratio
1:60-60:In 1 range, co-toxicity coefficient is all higher than 120, i.e. the composition shows the bioactivity of Rhizoctonia solani Kuhn
For synergistic effect；When the weight ratio of three octyl benzene sulfonate of biguanides and benzothiostrobin is 1:1-1:In 40 ranges, co-toxicity coefficient
It is all higher than 140.
Bioassay example 2：Three octyl benzene sulfonate of biguanides and benzothiostrobin compounding are to rice sheath blight disease field efficacy
Test method：Respectively in rice tillering latter stage, boot stage, cut phase, each dispenser of neat fringe pustulation period 1 time, altogether dispenser 4
It is secondary.Conventional spraying is made using WSB-16 type knapsack sprayers, there is the water layer of 3cm or so in water spray 750kg/hm2, field.It applies
Field keeps certain water layer, check plot to spray clear water when medicine.Be fine day on the day of dispenser in experiment, after medicine for 24 hours in non-rainfall.
Rice milky ripe stage is often handled cell and is sampled using 5 point types, and every is looked into 5 caves, looks into 25 cave rice altogether, records diseased plant number and by classification
Standard grading.Calculate diseased plant rate, disease index and control effect.
2 biguanides of table, three octyl benzene sulfonate and benzothiostrobin compounding are to rice sheath blight disease field efficacy
As seen from the above table, compared with exclusive use, three octyl benzene sulfonate of biguanides and benzothiostrobin are used in compounding can be with
The control effect to rice sheath blight disease is significantly improved, is had significant synergies, the amount of application of active constituent can be reduced, subtracted
The generation of slow drug resistance.Field observation, to crop safety.
The foregoing is merely presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification should all belong to the covering scope of the present invention.
Claims (6)
1. a kind of bactericidal composition containing three octyl benzene sulfonate and benzothiostrobin of biguanides, it is characterised in that：Its by effectively at
Three octyl benzene sulfonate of biguanides and benzothiostrobin compounding is divided to form 1:60-60:1.
2. bactericidal composition according to claim 1, it is characterised in that：The three octyl benzene sulfonate of biguanides and benzene
The weight ratio of thiophene bacterium ester is 1:1-1:40.
3. a kind of including any bactericidal composition of claim 1 to 2, it is characterised in that：Three octane of biguanides
The weight of base benzene sulfonate and benzothiostrobin accounts for the 10-50% of total weight, surplus be auxiliary pesticide-acceptable at.
4. bactericidal composition according to claim 3, it is characterised in that：The three octyl benzene sulfonate of biguanides and benzene
The weight of thiophene bacterium ester accounts for the 20-40% of pesticidal preparations total weight, surplus be auxiliary element auxiliary agent pesticide-acceptable, solvent or
Filler.
5. bactericidal composition according to claim 4, it is characterised in that：The dosage form of the pesticidal preparations is wettable powder
Agent, water dispersible granules, aqueous suspension agent, microcapsule suspending agent, granule or aqueous emulsion etc..
6. according to claim 1-5 any one of them bactericidal compositions, it is characterised in that：Prevention for rice sheath blight disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810279720.4A CN108294041B (en) | 2018-04-01 | 2018-04-01 | Bactericidal composition containing iminoctadine trioctylphenyl sulfonate and benzothiostrobin |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810279720.4A CN108294041B (en) | 2018-04-01 | 2018-04-01 | Bactericidal composition containing iminoctadine trioctylphenyl sulfonate and benzothiostrobin |
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| CN108294041A true CN108294041A (en) | 2018-07-20 |
| CN108294041B CN108294041B (en) | 2021-04-09 |
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| CN201810279720.4A Active CN108294041B (en) | 2018-04-01 | 2018-04-01 | Bactericidal composition containing iminoctadine trioctylphenyl sulfonate and benzothiostrobin |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110495458A (en) * | 2018-05-19 | 2019-11-26 | 安徽省农业科学院植物保护与农产品质量安全研究所 | A kind of bactericidal composition containing three octyl benzene sulfonate of coumoxystrobin and biguanides |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103229777A (en) * | 2013-05-08 | 2013-08-07 | 陕西农心作物科技有限公司 | Pyraclostrobin-containing sterilization composition |
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2018
- 2018-04-01 CN CN201810279720.4A patent/CN108294041B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103229777A (en) * | 2013-05-08 | 2013-08-07 | 陕西农心作物科技有限公司 | Pyraclostrobin-containing sterilization composition |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110495458A (en) * | 2018-05-19 | 2019-11-26 | 安徽省农业科学院植物保护与农产品质量安全研究所 | A kind of bactericidal composition containing three octyl benzene sulfonate of coumoxystrobin and biguanides |
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| CN108294041B (en) | 2021-04-09 |
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