CN108102037A - 一种亲水性水凝胶的制备方法 - Google Patents

一种亲水性水凝胶的制备方法 Download PDF

Info

Publication number
CN108102037A
CN108102037A CN201611054924.5A CN201611054924A CN108102037A CN 108102037 A CN108102037 A CN 108102037A CN 201611054924 A CN201611054924 A CN 201611054924A CN 108102037 A CN108102037 A CN 108102037A
Authority
CN
China
Prior art keywords
preparation
hydrophilic
monomer
methyl
hydrophilic hydrogel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611054924.5A
Other languages
English (en)
Inventor
陈广炎
刘飏
刘福军
罗建华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danyang Yaben Chemical Technology Co Ltd
Original Assignee
Danyang Yaben Chemical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danyang Yaben Chemical Technology Co Ltd filed Critical Danyang Yaben Chemical Technology Co Ltd
Priority to CN201611054924.5A priority Critical patent/CN108102037A/zh
Publication of CN108102037A publication Critical patent/CN108102037A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C08F283/065—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals on to unsaturated polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
    • C08G64/20—General preparatory processes
    • C08G64/30—General preparatory processes using carbonates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • C08K3/346—Clay
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/05—Alcohols; Metal alcoholates
    • C08K5/053—Polyhydroxylic alcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C08K2003/2237—Oxides; Hydroxides of metals of titanium
    • C08K2003/2241—Titanium dioxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)

Abstract

本发明涉及一种亲水性水凝胶的制备方法，该亲水性水凝胶按照重量百分比，由以下组分组成：含硅单体：25～55％；亲水单体：35～65％；聚乙二醇二丙烯酸酯：1～3％；交联剂：1～2％；填充剂：0.1～0.5％；保湿剂：5～10％。本发明制备的水凝胶无需表面改性等后处理，可直接佩戴。制备过程简单易操作，适合规模化生产。

Description

一种亲水性水凝胶的制备方法
技术领域
本发明涉及一种亲水性凝胶的制备方法，属于化学领域。
背景技术
在隐形眼镜使用过程中，需要进行保湿，普通的材料制作的隐形眼镜已经不能满足人们的佩戴需求，为改善水凝胶的透氧性能，达到使镜片能够佩戴过夜的目的，研究学者们纷纷将研究热点转向能够高透氧的硅水凝胶。有机硅水凝胶材料能够结合有机硅材料的高透氧性和水凝胶材料的柔软性，可以满足消费者舒适性及连续佩戴的需求，消除因佩戴缺氧而引起的相关症状。目前许多研究者致力于硅橡胶或硅水凝胶表面亲水改性，效果良好但工艺条件复杂，不适用于规模化加工生产。
有鉴于上述缺陷，有必要提出一种新型的亲水性水凝胶的制备方法。
发明内容
本发明的目的是提供一种新型的亲水性水凝胶的制备方法。
本发明的技术方案如下：
一种亲水性水凝胶的制备方法，其特征在于，该亲水性水凝胶按照重量百分比，由以下组分组成：
含硅单体：25～55％；
亲水单体：35～65％；
聚乙二醇二丙烯酸酯：1～3％；
交联剂：1～2％；
填充剂：0.1～0.5％；
保湿剂：5～10％。
进一步的，所述的含硅单体为甲基-二(三甲基硅氧烷基)-甲烷基丙基甲基丙烯酸甘油酯，或者甲基-二(三甲基硅氧烷基)-甲烷基丙基甲基丙烯酸甘油酯和甲基丙烯酰氧丙基三(三甲基硅氧基)硅烷组成的混合物。
进一步的，所述亲水单体为己内酯单体、三亚甲基碳酸酯单体、乙交酯单体中的一种或多种。
进一步的，所述交联剂为苯乙烯、a-甲基苯乙烯、丙烯腈、丙烯酸、甲基丙烯酸、乙二醛、氮丙啶中的任一种。
进一步的，所述填充剂为高岭土、二氧化钛、云母中的一种或多种。
进一步的，所述保湿剂为甘油、丙二醇、山梨醇中的一种或多种。
借由上述方案，本发明至少具有以下优点：
本发明中且亲水单体含量高。本发明实施例能够通过制备带有保湿剂的亲水性水凝胶，抗蛋白沉积性能好，人眼佩戴舒适。且制备的硅水凝胶无需表面改性等后处理，可直接佩戴。制备过程简单易操作，适合规模化生产。
具体实施方式
下面结合实施例对本发明作进一步说明。
具体实施例配方：
含硅单体：25～55％；
亲水单体：35～65％；
聚乙二醇二丙烯酸酯：1～3％；
交联剂：1～2％；
填充剂：0.1～0.5％；
保湿剂：5～10％。
具体制备方法是：
将亲水单体、含硅单体、聚乙二醇二丙烯酸酯在搅拌条件下均匀分散于保湿剂形成A组份，将交联剂在搅拌条件下形成B组份，将B组份和填充剂加入到A组份中，在真空条件下形成凝胶层，得到亲水性水凝胶。
实施例1
将25％甲基-二(三甲基硅氧烷基)-甲烷基丙基甲基丙烯酸甘油酯、65％三亚甲基碳酸酯单体、3％聚乙二醇二丙烯酸酯搅拌均匀后分散于5％的甘油中形成A组份，将1.5％的苯乙烯在搅拌下形成B组份，将B组份和0.5％的高岭土加入到A组份中，在真空条件下形成凝胶层，得到亲水性水凝胶。
实施例2
将55％甲基丙烯酰氧丙基三(三甲基硅氧基)硅烷、35％乙交酯单体、1％聚乙二醇二丙烯酸酯搅拌均匀后分散于6.5％的丙二醇中形成A组份，将2％的二氧化钛在搅拌下形成B组份，将B组份和0.5％的云母加入到A组份中，在真空条件下形成凝胶层，得到亲水性水凝胶。
实施例3
将42％甲基-二(三甲基硅氧烷基)-甲烷基丙基甲基丙烯酸甘油酯和甲基丙烯酰氧丙基三(三甲基硅氧基)硅烷组成的混合物、44％三亚甲基碳酸酯单体、2％聚乙二醇二丙烯酸酯搅拌均匀后分散于10％的丙二醇中形成A组份，将1.5％的丙烯腈在搅拌下形成B组份，将B组份和0.5％的高岭土加入到A组份中，在真空条件下形成凝胶层，得到亲水性水凝胶。
以上所述仅是本发明的优选实施方式，并不用于限制本发明，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明技术原理的前提下，还可以做出若干改进和变型，这些改进和变型也应视为本发明的保护范围。

Claims (6)

1.一种亲水性水凝胶的制备方法，其特征在于，该亲水性水凝胶按照重量百分比，由以下组分组成：
含硅单体：25～55％；
亲水单体：35～65％；
聚乙二醇二丙烯酸酯：1～3％；
交联剂：1～2％；
填充剂：0.1～0.5％；
保湿剂：5～10％。
2.根据权利要求1所述的一种亲水性水凝胶的制备方法，其特征在于：所述的含硅单体为甲基-二(三甲基硅氧烷基)-甲烷基丙基甲基丙烯酸甘油酯，或者甲基-二(三甲基硅氧烷基)-甲烷基丙基甲基丙烯酸甘油酯和甲基丙烯酰氧丙基三(三甲基硅氧基)硅烷组成的混合物。
3.根据权利要求1所述的一种亲水性水凝胶的制备方法，其特征在于：所述亲水单体为己内酯单体、三亚甲基碳酸酯单体、乙交酯单体中的一种或多种。
4.根据权利要求1所述的一种亲水性水凝胶的制备方法，其特征在于：所述交联剂为苯乙烯、a-甲基苯乙烯、丙烯腈、丙烯酸、甲基丙烯酸、乙二醛、氮丙啶中的任一种。
5.根据权利要求1所述的一种亲水性水凝胶的制备方法，其特征在于：所述填充剂为高岭土、二氧化钛、云母中的一种或多种。
6.根据权利要求1所述的一种亲水性水凝胶的制备方法，其特征在于：所述保湿剂为甘油、丙二醇、山梨醇中的一种或多种。
CN201611054924.5A 2016-11-25 2016-11-25 一种亲水性水凝胶的制备方法 Pending CN108102037A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611054924.5A CN108102037A (zh) 2016-11-25 2016-11-25 一种亲水性水凝胶的制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611054924.5A CN108102037A (zh) 2016-11-25 2016-11-25 一种亲水性水凝胶的制备方法

Publications (1)

Publication Number Publication Date
CN108102037A true CN108102037A (zh) 2018-06-01

Family

ID=62204362

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611054924.5A Pending CN108102037A (zh) 2016-11-25 2016-11-25 一种亲水性水凝胶的制备方法

Country Status (1)

Country Link
CN (1) CN108102037A (zh)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102964532A (zh) * 2012-11-29 2013-03-13 海昌隐形眼镜有限公司 一种有机硅水凝胶隐形眼镜材料及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102964532A (zh) * 2012-11-29 2013-03-13 海昌隐形眼镜有限公司 一种有机硅水凝胶隐形眼镜材料及其制备方法

Similar Documents

Publication Publication Date Title
JPS58169127A (ja) シリコン含有コンタクトレンズ原料およびこれより作られたコンタクトレンズ
CN1073842C (zh) 含水分散液的化妆或局部涂敷用途
CN107531847A (zh) 基于有机硅的亲水共聚物和包括其的水凝胶组合物
CN106062043B (zh) 亲水性有机硅组合物
DE60040090D1 (de) Kontaktlinse
CN1059099A (zh) 调理纤维质和皮肤用的稳定液态制品
CN1305801A (zh) 含两性淀粉和阳离子调理剂的化妆品组合物及其用途
CN102964532A (zh) 一种有机硅水凝胶隐形眼镜材料及其制备方法
CN104044285A (zh) 具有稳定特征的眼科装置
CN104357595B (zh) 赋予皮革屏蔽紫外线功能的皮革加脂剂及其制备方法
CN1205909C (zh) 含有乙烯基二甲聚硅氧烷/二甲聚硅氧烷共聚物水性乳液和增稠剂的化妆品组合物及其用途
CN1242982A (zh) 含聚有机硅氧烷和丙烯酸三元共聚物的化妆品组合物,以及该组合物用于处理角质物质的应用
CN1292256A (zh) 用于洗涤角蛋白材料的组合物
CN104321352B (zh) 可聚合的含酰胺基的有机硅化合物、含硅聚合物以及由其制备的生物医学装置
CN108102038A (zh) 一种水凝胶
CN108102049A (zh) 水凝胶的制备方法
CN108102037A (zh) 一种亲水性水凝胶的制备方法
CN108102047A (zh) 水凝胶
CN108102039A (zh) 一种水凝胶的制备方法
CN104788879B (zh) 一种抗电击橡胶鞋底及其制备方法
CN203965744U (zh) 具有滤蓝光及抗uv功能的彩色隐形眼镜
CN206468864U (zh) 恒流器
CN205929867U (zh) 一种卷烟包装专用防水印刷薄膜
KR101152801B1 (ko) 이형성을 갖는 ｐｅｔ 시트용 양이온성 대전방지제
CN105088795B (zh) 一种合成革用水性消光表面处理剂的制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20180601

WD01 Invention patent application deemed withdrawn after publication