CN108101842B - 一种2-羟基-4-羧基喹啉的制备方法 - Google Patents
一种2-羟基-4-羧基喹啉的制备方法 Download PDFInfo
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- CN108101842B CN108101842B CN201711469792.7A CN201711469792A CN108101842B CN 108101842 B CN108101842 B CN 108101842B CN 201711469792 A CN201711469792 A CN 201711469792A CN 108101842 B CN108101842 B CN 108101842B
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- Prior art keywords
- acetic acid
- glacial acetic
- hydroxy
- carboxyquinoline
- isatin
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (8)
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CN201711469792.7A CN108101842B (zh) | 2017-12-29 | 2017-12-29 | 一种2-羟基-4-羧基喹啉的制备方法 |
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CN201711469792.7A CN108101842B (zh) | 2017-12-29 | 2017-12-29 | 一种2-羟基-4-羧基喹啉的制备方法 |
Publications (2)
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CN108101842A CN108101842A (zh) | 2018-06-01 |
CN108101842B true CN108101842B (zh) | 2021-04-30 |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20140075082A (ko) * | 2012-12-10 | 2014-06-19 | 주식회사 이큐스앤자루 | 디하이드로퀴놀린 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 인플루엔자 a형 바이러스에 의한 질환의 예방 또는 치료용 약학적 조성물 |
CN104302624A (zh) * | 2012-04-10 | 2015-01-21 | 邓迪大学 | 抗疟疾剂 |
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2017
- 2017-12-29 CN CN201711469792.7A patent/CN108101842B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104302624A (zh) * | 2012-04-10 | 2015-01-21 | 邓迪大学 | 抗疟疾剂 |
KR20140075082A (ko) * | 2012-12-10 | 2014-06-19 | 주식회사 이큐스앤자루 | 디하이드로퀴놀린 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 인플루엔자 a형 바이러스에 의한 질환의 예방 또는 치료용 약학적 조성물 |
Non-Patent Citations (1)
Title |
---|
Synthesis of the pentacyclic core of lihouidine;Ken S. Feldman et al.;《Tetrahedron Letters》;20080201;第49卷;第2137页Scheme 2 * |
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Publication number | Publication date |
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CN108101842A (zh) | 2018-06-01 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of 2-hydroxy-4-carboxyquinoline Effective date of registration: 20220616 Granted publication date: 20210430 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |
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Date of cancellation: 20230726 Granted publication date: 20210430 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |
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