CN1077896A - Medicine for psoriasis and manufacture method - Google Patents

Medicine for psoriasis and manufacture method Download PDF

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Publication number
CN1077896A
CN1077896A CN 93102501 CN93102501A CN1077896A CN 1077896 A CN1077896 A CN 1077896A CN 93102501 CN93102501 CN 93102501 CN 93102501 A CN93102501 A CN 93102501A CN 1077896 A CN1077896 A CN 1077896A
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radix
rhizoma
salviae miltiorrhizae
paeoniae rubra
grams
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CN 93102501
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曲贵民
高长荣
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Individual
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Individual
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Abstract

A kind of psoriatic curative and manufacture method, be specially adapted to the treatment of blood dispersing wind dryness psoriasis pustulosa, this medicine is made up of Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Et Rhizoma Rhei, Rhizoma Curcumae, rhizoma sparganic, Cortex Dictamni, Herba Schizonepetae, Fructus Arctii, Radix Scutellariae, Radix Angelicae Sinensis, Radix Rehmanniae and Radix Glycyrrhizae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra are ground into fine powder, all the other medical materials extract with alcohol reflux and decocting, make watered pill grain then.This medicine has significant curative effect to the blood dispersing wind dryness psoriasis pustulosa, clinical observation 106 routine patients, and total effective rate is 91.4%, cure rate 71.6%, relapse rate is very low.

Description

Medicine for psoriasis and manufacture method
The present invention relates to treat psoriatic Chinese medicine and preparation method thereof.
Psoriasis is that commonly encountered diseases is come frequently-occurring disease, does not still have satisfied therapy at present.The western medicine medicine is a lot of, is summarised as immunosuppressant, hormone, photochemical therapy etc., but only can alleviate for the moment, can not cure, and all serious side effects be arranged.The treatment by Chinese herbs medicine is also more, as Pilulae Indigo Naturalis, KEYIN PIAN all based on heat-clearing and toxic substances removing, removing heat from blood, be intended to treat the blood heat wind-dryness type psoriasis, XIAOYIN PIAN is based on heat-clearing and toxic substances removing, removing heat from blood, nourishes blood, and is intended to treat blood heat wind-dryness type psoriasis and blood-deficiency and wind-dry psoriasis pustulosa.But above three kinds of Chinese medicines still do not have obvious curative effects to treatment blood dispersing wind dryness psoriasis pustulosa.
The object of the present invention is to provide a kind of the blood dispersing wind dryness psoriasis pustulosa to be had the Chinese medicine of significant curative effect, and the method for making this medicine is provided, cause this medicine can realize suitability for industrialized production.
Technical solution of the present invention is that medicine for psoriasis is made up of Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Et Rhizoma Rhei, Rhizoma Curcumae, rhizoma sparganic, Cortex Dictamni, Herba Schizonepetae, the other son of cattle, Radix Scutellariae, Radix Angelicae Sinensis, Radix Rehmanniae and Radix Glycyrrhizae, and the percentage by weight of each composition is: Radix Salviae Miltiorrhizae 6-16, Radix Sophorae Flavescentis 6-16, Rhizoma Corydalis 2-10, Rhizoma Chuanxiong 2-8, Radix Paeoniae Rubra 3-10, Radix Et Rhizoma Rhei 2-10, Rhizoma Curcumae 3-10, rhizoma sparganic 2-7, Cortex Dictamni 2-10, Herba Schizonepetae 2-10, cattle other sub-2-10, Radix Scutellariae 2-10, Radix Angelicae Sinensis 2-10, Radix Rehmanniae 7-13, Radix Glycyrrhizae 1-10.
The manufacture method of medicine for psoriasis of the present invention, finish through following steps:
A, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra are cleaned oven dry, are ground into fine powder, cross 120 mesh sieves,
In b, all the other 12 flavor medical materials, add 70% alcohol reflux 12 hours of 7 times of amounts of its weight, collect filtrate afterwards,
Add water in c, the medicinal residues, decocted 2 times in 2 hours, 1 hour respectively, gradation quiescent setting 12 hours is got supernatant,
The filtrate that d, merging are collected becomes thick paste with supernatant concentration, mixes back pill grain with Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra fine powder, drying, coating, glazing, pack then.
Prescription of the present invention is a monarch drug with Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis.Record in " Japan hanako materia medica " " Radix Salviae Miltiorrhizae is got its bitter in the mouth and is slightly cold and not only invigorates blood circulation but also removing heat from blood, and can nourish blood, and controls the malignant boil scabies, wart go to live in the household of one's in-laws on getting married toxic swelling "; Radix Sophorae Flavescentis is with heat clearing and damp drying, and dispelling wind for relieving itching is apt to control scabies and skin pruritus.Minister is with Rhizoma Corydalis, CHUANSHAO, Radix Paeoniae Rubra.Rhizoma Corydalis and Rhizoma Chuanxiong blood-activating and qi-promoting; Record " Radix Paeoniae Rubra promoting the circulation of blood removing blood stasis with potent drugs moves back heat in blood merit carbuncle skin ulcer, controls scabies " in " the southern regions of the Yunnan Province book on Chinese herbal medicine ".Above three and Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis 5 usefulness can strengthen blood-activating and qi-promoting, the merit of removing blood stasis with potent drugs.Assistant is with Radix Et Rhizoma Rhei, Rhizoma Curcumae, rhizoma sparganic.Record " Radix Et Rhizoma Rhei is captured stagnant, the removing pathogenic heat from blood and toxic substance from the body eliminating blood stasis and inducing menstruation " in " herbal classic "; Blood in the Rhizoma Curcumae energy dispelling the stagnated QI; Gas in the rhizoma sparganic energy removing blood stasis, the power that Rhizoma Curcumae, its removing blood stasis of the two mutual reinforcement between of rhizoma sparganic are opened the stasis of blood is strong, and three's mutual reinforcement between removing blood stasis repercussive is again with favus skin, Herba Schizonepetae, the other son of cattle, Radix Scutellariae heat-clearing and toxic substances removing, record in the dispelling wind for relieving itching, " property of medicine opinion " " favus skin is controlled all pyretic toxicity aversion to wind, wind skin ulcer scabies, red mashed "; Record in " herbal classic " " Herba Schizonepetae is dispeled the wind, induces sweat, rash ", " Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication "; Record in " not Lu " " the other sub-dispelling wind and heat pathogens of cattle, detoxifcation rash ".Multiple assistant can be moistened foster skin with Radix Angelicae Sinensis, Radix Rehmanniae, Radix Glycyrrhizae, the invigorating middle warmer of blood enriching and dryness moistening QI invigorating, makes skin soft and moist and white scales must move back, and matches with the promoting blood circulation and breaking stagnation person again, makes it removing blood stasis and does not just hinder.Record " Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation " in " herbal classic ", " Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting ", the invigorating middle warmer of Radix Glycyrrhizae QI invigorating, heat-clearing and toxic substances removing relaxes the property of medicine.
Comprehensive full side is total to the Minato blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, and the effect of dispelling wind for relieving itching, thus be applicable to the blood dispersing wind dryness psoriasis pustulosa, and significant curative effect is arranged.
Chinese medicine of the present invention can be made the grain ball with said method, also can make big ball, electuary, tablet, capsule etc. with additive method, and wherein the drug effect of grain ball is the highest.
The present invention compared with prior art has the following advantages:
1, drug dose and composition are constant, and the raw material source is wide, and cost is low, and medicinal alcohol reflux and decocting extraction in 4/5ths are arranged, and improve drug effect.
2, the various raw materials that adopt of the present invention are the medical material of the no side effects that records of Chinese Pharmacopoeia, drug safety, reliable.
3, this Chinese medicine is to 106 routine blood dispersing wind dryness psoriasis pustulosa patients, through clinical observation result, and the stasis of blood of fullying recover from an illness rate 71.6%, effective percentage 19.8%, total effective rate is 91.4%, relapse rate is low.
4, this oral medicinal herb, outer sick treatment by oral administration of medicines takes stopgap measures and effects a permanent cure, and has opened up a new way for treating obstinate blood dispersing wind dryness psoriasis pustulosa.
Further specify technical solution of the present invention in conjunction with the embodiments.
Example 1
1, gets Radix Salviae Miltiorrhizae 15 grams, Rhizoma Chuanxiong 9 grams, the clean oven dry of Radix Paeoniae Rubra 10 grams, be ground into fine powder, cross 120 mesh sieves.
2, get Radix Sophorae Flavescentis 15 gram, Rhizoma Corydalis 10 grams, Radix Et Rhizoma Rhei 10 grams, Rhizoma Curcumae 10 grams, rhizoma sparganic 9 grams, Cortex Dictamni 5 grams, Herba Schizonepetae 5 grams, other son 5 grams of cattle, Radix Scutellariae 5 grams, Radix Angelicae Sinensis 5 grams, Radix Rehmanniae 10 grams, Radix Glycyrrhizae 4 grams and add 889 grams, 70% alcohol heating reflux again and extracted 12 hours, collect filtrate afterwards.
3, add entry in the medicinal residues, decocted 2 times in 2 hours, 1 hour respectively, gradation quiescent setting 12 hours is got supernatant.
4, the filtrate of merge collecting becomes thick paste with supernatant concentration, mixes back pill grain with Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra fine powder, then drying, coating, glazing, pack 9 bags of Chinese medicines, every bag heavy 7 restrains.
Example 2
Get Radix Salviae Miltiorrhizae 10 grams, Rhizoma Chuanxiong 5 grams, Radix Paeoniae Rubra 10 grams, Radix Sophorae Flavescentis 15 grams, Rhizoma Corydalis 5 grams, Radix Et Rhizoma Rhei 10 grams, Rhizoma Curcumae 5 grams, rhizoma sparganic 5 grams, Cortex Dictamni 10 grams, Herba Schizonepetae 5 grams, other son 10 grams of cattle, Radix Scutellariae 10 grams, Radix Angelicae Sinensis 5 grams, Radix Rehmanniae 14 grams, Radix Glycyrrhizae 4 grams, by the method for example 1 produce 8 bags of Chinese medicines of the present invention, every bag heavy 7 the gram.
Example 3
Get Radix Salviae Miltiorrhizae 1500 grams, Rhizoma Chuanxiong 1000 grams, Radix Paeoniae Rubra 1000 grams, Radix Sophorae Flavescentis 1500 grams, Rhizoma Corydalis 1000 grams, Radix Et Rhizoma Rhei 500 grams, Rhizoma Curcumae 500 grams, rhizoma sparganic 500 grams, Cortex Dictamni 1000 grams, Herba Schizonepetae 1000 grams, other son 1000 grams of cattle, Radix Scutellariae 1000 grams, Radix Angelicae Sinensis 1000 grams, Radix Rehmanniae 1000 grams, Radix Glycyrrhizae 500 grams, by the method for example 1 produce 1000 bags of Chinese medicines of the present invention, every bag heavy 7 the gram.
The Chinese medicine of above embodiment contains matrine for every bag and is not less than 0.7 gram.This Chinese medicine is grown up each 1 to 2 bag, every day 3 warm water delivery services, children's is cut down according to the circumstance, 30 days was 1 course of treatment, was as the criterion with 5 course of therapy.

Claims (2)

1, a kind of psoriatic curative, the curative of blood dispersing wind dryness psoriasis pustulosa particularly, it is characterized in that being made up of Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Et Rhizoma Rhei, Rhizoma Curcumae, rhizoma sparganic, Cortex Dictamni, Herba Schizonepetae, the other son of cattle, Radix Scutellariae, Radix Angelicae Sinensis, Radix Rehmanniae and Radix Glycyrrhizae, the percetage by weight of each composition is Radix Salviae Miltiorrhizae 6-16, Radix Sophorae Flavescentis 6-16, Rhizoma Corydalis 2-10, Rhizoma Chuanxiong 2-8, Radix Paeoniae Rubra 3-10, Radix Et Rhizoma Rhei 2-10, Rhizoma Curcumae 3-10, rhizoma sparganic 2-7, Cortex Dictamni 2-10, Herba Schizonepetae 2-10, cattle other sub-2-10, Radix Scutellariae 2-10, Radix Angelicae Sinensis 2-10, Radix Rehmanniae 7-13, Radix Glycyrrhizae 1-10.
2, make the method for the described product of claim 1, it is characterized in that finishing through following steps:
A, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra are cleaned oven dry, are ground into fine powder, cross 120 mesh sieves,
In b, all the other 12 flavor medical materials, add 7 times of 70% alcohol reflux of its weight 12 hours, collect filtrate afterwards,
Add water in c, the medicinal residues, decocted 2 times in 2 hours, 1 hour respectively, gradation quiescent setting 12 hours is got supernatant,
The filtrate that d, merging are collected becomes thick paste with supernatant concentration, mixes back pill grain with Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra fine powder, drying, coating, glazing, pack then.
CN 93102501 1993-03-11 1993-03-11 Medicine for psoriasis and manufacture method Pending CN1077896A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053580C (en) * 1996-04-05 2000-06-21 李国雄 Yuxianwan pill for curing psoriasis
CN1078084C (en) * 1999-12-13 2002-01-23 朱卫国 Medicinal composition for treating psoriasis
US7615239B2 (en) * 2002-04-15 2009-11-10 Tetsuo Santo Tea for treating dermatitis comprising herbal extracts
US7906159B2 (en) 2008-04-17 2011-03-15 Vivien Chou Herbal compositions and methods for enhancing vital energy and athletic performance
CN102114230A (en) * 2011-02-21 2011-07-06 刘绍居 Medicament for treating psoriasis
CN104189822A (en) * 2014-08-25 2014-12-10 河南科技大学第一附属医院 Psoriasis coating paste and preparation method thereof
CN104208533A (en) * 2014-09-17 2014-12-17 山西忻州兴华皮肤病专科医院 Drug for treating pustular psoriasis
CN105169296A (en) * 2015-11-08 2015-12-23 长沙佰顺生物科技有限公司 Traditional Chinese medicine composition for treating psoriasis
CN105497734A (en) * 2015-12-31 2016-04-20 孙伟 Medicament for treating radiation enteritis and preparation method thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053580C (en) * 1996-04-05 2000-06-21 李国雄 Yuxianwan pill for curing psoriasis
CN1078084C (en) * 1999-12-13 2002-01-23 朱卫国 Medicinal composition for treating psoriasis
US7615239B2 (en) * 2002-04-15 2009-11-10 Tetsuo Santo Tea for treating dermatitis comprising herbal extracts
US7906159B2 (en) 2008-04-17 2011-03-15 Vivien Chou Herbal compositions and methods for enhancing vital energy and athletic performance
US8119170B2 (en) 2008-04-17 2012-02-21 Wen Hsien Chou Herbal compositions and methods for enhancing vital energy and athletic performance
CN102114230A (en) * 2011-02-21 2011-07-06 刘绍居 Medicament for treating psoriasis
CN102114230B (en) * 2011-02-21 2012-07-04 刘绍居 Medicament for treating psoriasis
CN104189822A (en) * 2014-08-25 2014-12-10 河南科技大学第一附属医院 Psoriasis coating paste and preparation method thereof
CN104208533A (en) * 2014-09-17 2014-12-17 山西忻州兴华皮肤病专科医院 Drug for treating pustular psoriasis
CN104208533B (en) * 2014-09-17 2017-09-05 山西忻州兴华皮肤病专科医院 A kind of medicine for treating psoriasis pustulosa
CN105169296A (en) * 2015-11-08 2015-12-23 长沙佰顺生物科技有限公司 Traditional Chinese medicine composition for treating psoriasis
CN105497734A (en) * 2015-12-31 2016-04-20 孙伟 Medicament for treating radiation enteritis and preparation method thereof

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