CN107751880A - A kind of dust composition and preparation method of the improvement enteric microorganism containing prebiotics - Google Patents
A kind of dust composition and preparation method of the improvement enteric microorganism containing prebiotics Download PDFInfo
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- CN107751880A CN107751880A CN201711218253.6A CN201711218253A CN107751880A CN 107751880 A CN107751880 A CN 107751880A CN 201711218253 A CN201711218253 A CN 201711218253A CN 107751880 A CN107751880 A CN 107751880A
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- powder
- black fungus
- oligosaccharide
- celery
- spinach
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The present invention relates to food, the technical field of health care, the dust composition and preparation method of specifically a kind of improvement enteric microorganism containing prebiotics.The composition of the dust composition is made up of celery powder, spinach powder, black fungus powder, hawthorn powder, red date powder, strawberry powder, galactooligosaccharide, isomalto-oligosaccharide, FOS, xylo-oligosaccharide raw material.This product composition is packed after ultrasonic wave cleans using sterileization automated packaging equipment.The products taste is good, there is promotion gastrointestinal motility, improves enteric microorganism composition, improves the effect of immunity.
Description
Technical field
The present invention relates to food, the technical field of health care, specifically a kind of improvement enteric microorganism containing prebiotics
Dust composition and preparation method.
Background technology
Enteron aisle is the maximum digestive organs of human body.Human intestinal microorganisms group is a complicated ecosystem, main bag
Bacterium and other microorganisms are included, such as fungi, parasite, virus and Archimycetes.Enteric microorganism take part in the multinomial life in enteron aisle
Reason activity, it is the indispensable pith of the daily vital movement of human body.In recent years research constantly confirms enteric microorganism and people
Body health is closely related.
In human body intestinal canal, including more than 1014, about 1.5 kilograms, the bacterium more than 1000 kinds.Enteric microorganism, which is divided into, to be had
Beneficial bacteria, harmful bacteria and neutral bacterium.Beneficial bacterium accounts for more than the 90% of total bacteria count, and main body is Bifidobacterium, Bacillus acidi lactici etc., is human body
The indispensable key element of health, can synthesize various vitamins, participate in the digestion of food, promote intestines peristalsis, suppress pathogenic bacteria
The growth of group, decompose harmful, noxious material etc..Harmful bacteria, if raised growth, a variety of diseases will be triggered, produce carcinogenic substance
Etc. harmful substance, or influence the function of immune system.Neutral bacterium, the i.e. bacterium with double action, such as Escherichia coli, intestines ball
Bacterium etc., it is beneficial to health under normal circumstances, if proliferation out of control, or it is transferred to other positions of body from enteron aisle, it is possible to trigger
Many problems.
Intestines problem may cause the symptoms such as poor appetite, nausea, stomachache, diarrhoea, constipation.In recent years, more and more
Research shows that enteric microorganism plays an important role in chronic gut inflammation, diarrhoea, constipation and other diseases are improved.And enteron aisle is micro-
Biology can be improved intestinal barrier function, body metabolism be adjusted with regulating system and mucosal immunity function.There is research to point out,
The ratio of beneficial bacterium reaches 70% in physically strong people's enteron aisle, and ordinary people is then 25%, and constipation crowd is reduced to 15%, and cancer
The ratio of probiotics in disease patient's enteron aisle only has 10%.
Prebiotics mainly includes various oligosaccharide kind materials or oligosaccharide (being made up of 2~10 molecule monose), such as oligomeric
Fructose, lactulose and galactooligosacchari(es, and the functional oligosaccharide such as isomaltulose, LS 55L.Prebiotics will not be disappeared by human body
Change system decomposition, can adjust enteron aisle, selective to allow specific intestinal beneficial bacterium --- refer mainly to Bifidobacterium and sent out with lactic acid bacteria
Ferment utilizes, and speedup breeding, is advantageous to health.It is thorn to short chain fatty acids caused by the fermentation of prebiotics by E
Swash an important factor for Bifidobacterium increases.
The organic acid that intestinal flora metabolism food is generated, the energy of needed by human body on the one hand can be provided, on the other hand,
Gut pH can be reduced, forms the environment for being unfavorable for pathogen existence, so as to effectively suppress enteron aisle corruption, and is improved to mineral member
The absorptivity of element, promote intestines peristalsis and be advantageous to defecation.
The content of the invention
Present invention aims at the dust composition for providing a kind of improvement enteric microorganism containing prebiotics and preparation side
Method, said composition have a variety of prebioticses, can adjust gut flora balance, increase beneficial bacterium quantity, in nutritional ingredient and health care
There is synergy in terms of function.
The present invention is achieved by the following technical solutions：
A kind of dust composition of the improvement enteric microorganism containing prebiotics, it forms the following originals included by weight
Material：Celery powder 50-70g, spinach powder 20-40g, black fungus powder 10-20g, hawthorn powder 10-20g, red date powder 15-25g, strawberry powder
10-20g, galactooligosaccharide 10-20g, isomalto-oligosaccharide 10-20g, FOS 10-20g, xylo-oligosaccharide 10-20g.
Preferably, the dust composition of the improvement enteric microorganism containing prebiotics of the present invention, consisting of by weight
Following raw materials of gauge：Celery powder 60g, spinach powder 30g, black fungus powder 15g, hawthorn powder 15g, red date powder 20g, strawberry powder 15g,
Galactooligosaccharide 15g, isomalto-oligosaccharide 15g, FOS 10g, xylo-oligosaccharide 15g.
Present invention also offers a kind of preparation method of the dust composition of the improvement enteric microorganism containing prebiotics, tool
Body step is as follows：
(1) celery, spinach, hawthorn, jujube, strawberry are cleaned, celery segment, black fungus soaks 3-4h with 15-25 DEG C of water；
Above-mentioned ready raw material is put into ultrasonic ozone combination fruit-vegetable cleaner, 20-40min is cleaned in 60W, 40kHz；
(2) celery is put into -20 DEG C of freezing 1.5h, crushed immediately, then be placed in ultrafine crusher after ultrasonic wave cleans
30min is crushed, obtains the celery powder of 500 mesh, it is stand-by in the container of good seal；
(3) black fungus after ultrasonic wave is cleaned, is scalded with boiling water, is placed in baking oven, 50 DEG C of baking 8-10 hours, naturally cold
But, obtain drying black fungus, dried black fungus used into ultra-fine pulverizer disintegrating 15min, obtains 500 mesh black fungus powders,
It is stand-by in the container of good seal；
(4) spinach after ultrasonic wave is cleaned drains away the water, and is dried 6 hours at 55 DEG C, and natural cooling will be dried
Spinach is tentatively crumbed, then is put into 10min in ultra-fine pulverizer disintegrating, is obtained 500 mesh spinach powders, is treated in the container of good seal
With；
(5) hawthorn after ultrasonic wave is cleaned is drained away the water, and is enucleated, and section, is put into baking box, and 80 DEG C are dried 2 hours, then will
Temperature is down to 50-60 DEG C and is further continued for drying half an hour, natural cooling in an oven after the time terminates, uses ultra-fine pulverizer disintegrating
10min, that is, 300 mesh hawthorn powders are obtained, it is stand-by in the container of good seal；
(6) jujube after ultrasonic wave is cleaned, is drained away the water, and removes jujube core, cuts in half, be put into baking box, and 80 DEG C are dried 2
Hour, then cool the temperature to 50-60 DEG C and be further continued for drying half an hour, natural cooling in an oven after the time terminates, it is cool after jujube
Ultra-fine pulverizer disintegrating 10min is put into, that is, obtains 300 mesh red date powders, it is stand-by in the container of good seal；
(7) the strawberry stalk after ultrasonic wave is cleaned, is thinly sliced, is put into baking box, and 80 DEG C are dried 2 hours, then by temperature
Be down to 50-60 DEG C to be further continued for drying half an hour, natural cooling in an oven after the time terminates, it is cool after jujube be put into ultrafine crusher
10min is crushed, that is, obtains 300 mesh strawberry powders, it is stand-by in the container of good seal；
(8) using equivalent progressively increase method by ready celery powder 50-70g, spinach powder 20-40g, black fungus powder 10-20g,
Hawthorn powder 10-20g, red date powder 15-25g, strawberry powder 10-20g are well mixed, and then sequentially add galactooligosaccharide 10-
20g, isomalto-oligosaccharide 10-20g, FOS 10-20g, xylo-oligosaccharide 10-20g, it is stirring while adding, after being well mixed, adopt
Packed with sterileization automated packaging equipment.
The dust composition eating method of the present invention is as follows：Half an hour takes the improvement containing prebiotics of the 3g present invention before the meal
The dust composition of enteric microorganism can be taken in 35-42 DEG C of warm water after being stirred with soup ladle.
Each property of raw material is as follows in detail in the present invention：
Celery is high fiber food, can accelerate the digestion and exclusion of stomach, and its enteral digested effect produces a kind of wood
The material of quality or enteral fat, this kind of material are a kind of antioxidants.Simultaneously have convenient gut purge, calming liver and clearing heat, moisten the lung and relieve the cough,
Brain tonic calmness, stomach invigorating profit blood and other effects.Nutrition and Food Safety Office of China Disease Prevention and control Centre is written《Chinese food into
Divide table (2002)》It has been shown that, 12 kilocalories of every 100 grams of nutritional ingredient energy, 0.05 milligram of vitamin B6,0.6 gram of protein, fat
0.1 gram of fat, 4.8 grams of carbohydrate, the microgram of folic acid 29.8,2.6 grams of dietary fiber, the microgram of vitamin A 5, carrotene 29 are micro-
Gram, 0.01 milligram of thiamine, 0.03 milligram of riboflavin, 0.22 milligram of nicotinic acid, 4 milligrams of vitamin C, 36 milligrams of calcium, 35 milligrams of phosphorus,
15 milligrams of potassium, 313.3 milligrams of sodium, 15 milligrams of magnesium, 0.2 milligram of iron, 0.1 milligram of zinc, the microgram of selenium 0.1,0.02 milligram of copper, manganese 0.06
Milligram.Also have lowering blood pressure and blood fat, preventing and treating dynamic containing materials such as volatile oil, apiin, bergapten, organic acids in addition
The effect of pulse atherosclerosis；Also there is certain auxiliary dietary function to neurasthenia, gout, muscle cramp；It can also promote stomach
Liquid is secreted, and increases appetite.Particularly the elderly, it is susceptible to suffer from stool because body movement amount is small, dietary amount is few, amount of drinking water is insufficient and does
It is dry, often have some celery can stimulating gastrointestinal wriggle be beneficial to defecation.
Containing abundant carrotene, vitamin C, vitamin K, calcium, phosphorus in spinach, and it is a certain amount of iron, vitamin E, auxiliary
The multiple beneficial composition such as enzyme Q10.The substantial amounts of plant crude fiber that spinach contains, can promote the effect of intestines peristalsis, beneficial to defecation,
And pancreatic secretion can be promoted, help digest.There is treatment to make for illnesss such as habitual constipation, anal fissure, hemorrhoid, chronic pancreatitis
With.In addition, it is beneficial to scurvy, high blood pressure, anaemia, diabetes, yctalopia patient et al..
The nutritional ingredient of black fungus, is analyzed according to modern science, and 10.6 grams of protein, fat 0.2 are contained in every 100 grams of dry products
Gram, 65 grams of carbohydrate, 7 grams of crude fibre, 375 milligrams of calcium, 201 milligrams of phosphorus, 185 milligrams of iron, additionally contain vitamin
B10.15 milligrams, 0.55 milligram of vitamin B2,2.7 milligrams of nicotinic acid.Cellulose in black fungus promotes enterocinesia, and black fungus has
The dust that remains in digestion, impurity absorption can be put together row by certain adsorption capacity, colloid in black fungus
Go out in vitro, intestines are washed so as to play a part of clearing stomach.Black fungus enters stomach, liver, large intestine channel, can moisturize sharp intestines, moistening lung benefit stomach, and relaxing muscles and tendons is lived
Network, fill blood.Treat constipation, the disease such as deficiency of blood gas loses, cough due to deficiency of the lung, intestines wind hemorrhoid blood and traumatic injury.
Hawthorn is containing multivitamin, tartaric acid, citric acid, crataegolic acid, malic acid etc., also containing flavonoids, lactone, sugar
The mineral matter such as class, protein, fat and calcium, phosphorus, iron, contained lipolytic enzyme can promote the digestion of fat food.In addition, hawthorn
It can treat constipation, there is defaecation, preventing and treating dry mouth be yearningly and constipation caused by body fluid loses can be used.
Jujube contains protein, organic acid, a large amount of glucides, predominantly glucose, also containing fructose, sucrose and by Portugal
Oligosaccharide, araban and galacturonan of grape sugar and fructose composition etc.；Contain substantial amounts of vitamin C, riboflavin, thiamines
The multivitamins such as element, carrotene, niacin；The abundant nutrition such as lot of trace calcium and amino acid.Jujube have compared with
Strong tonify deficiency benefit health, nourishing blood and tranquilization, strengthening the spleen and stomach and other effects, immune function of human body can be improved, strengthen resistance against diseases.
Strawberry nutrition value is abundant, is described as being " fruit queen ", contains abundant vitamin C, vitamin A, vitamin
E, nicotinic acid, vitamin B1, vitamin B2, carrotene, tannic acid, aspartic acid, copper, strawberry amine, pectin, cellulose, leaf
The nutriments such as acid, iron, calcium, ellagic acid and anthocyanidin.Rich in abundant dietary fiber in strawberry, the compacted of intestines and stomach can be promoted
It is dynamic, promote the food digestion in intestines and stomach, improve constipation, prevent the generation of acne, intestinal cancer.
Galactooligosaccharide (GOS) is a kind of functional oligose with natural attribute, and its molecular structure is usually half
1~7 galactosyl is connected on lactose or glucose molecule.In nature, micro GOS in the milk of animal be present, and
Content is more in lacto, and the foundation of the species population in infants relies heavily on the GOS compositions in breast milk.It is low
Poly- galactolipin has stronger acid resistance, heat resistance, will not divide because of high temperature sterilization in process and human body hydrochloric acid in gastric juice
Solve and lose its characteristic.Galactooligosaccharide is the fabulous nutrition of the beneficial bacteriums such as Bifidobacterium in human body intestinal canal, Lactobacillus acidophilus
Source and effective proliferation factor, the digestion and absorption function of human body intestinal canal can be improved.
Isomalto-oligosaccharide is a kind of emerging functional oligose.Without hydrolysis isomalto-oligosaccharide in the enteron aisle of animal
Enzymatic hydrolysis system, therefore, they are not digested absorption, and it is preferably that Bifidobacterium is utilized to be directly entered big enteral, can be efficient
Breed beneficial bacterium in enteron aisle.Isomalto-oligosaccharide is that the beneficial bacterium in enteron aisle absorbs decomposition, produced big after human body intestinal canal is entered
The short chain fatty acids of amount, intestines peristalsis, increase excrement degree of wetting can be stimulated and keep certain osmotic pressure.Pass through phosphatidic acid and intestines
Mucosal epithelial cells are cooperated, and intestinal mucosa surface is occupied jointly with other anaerobic bacterias, form one layer of life with protective effect
Thing envelope barrier, suppress the propagation of external source pathogenic bacteria and the intrinsic putrefactivebacteria of enteral, reduce poisonous tunning and harmful bacteria
Produce, so as to reach purification enteron aisle, promotion enterocinesia, prevent treating constipation, enhancement immunity of organisms, improve intestinal environment and protection intestines
The effect in road.
FOS can be obviously improved microbial population ratio in enteron aisle, to profitable strain in enteron aisle such as Bifidobacterium Bifidum, breast
The selective proliferation function such as acidfast bacilli, the generation of enteral corrupt substance is reduced and suppressed, suppresses the growth of harmful bacteria, adjusted
Enteron aisle inner equilibrium；The absorption and utilization of trace elements iron, calcium can be promoted, to prevent osteoporosis；Hepatotoxin, energy can be reduced
The organic acid of anticancer is generated in intestines, there is significant preventing cancer function, strengthens immunity of organisms.
Xylo-oligosaccharide (XOS) is combined into by 2-7 xylose molecule with β-Isosorbide-5-Nitrae glycosidic bond.Xylo-oligosaccharide is not digested suction
Receive, go directly colon.The primary efficacy of xylo-oligosaccharide plays a role in colon, while it promotes beneficial bacterium growth breeding
Suppress the growth of the harmful bacterias such as Escherichia coli, finally promote Tiny ecosystem flora in body to reach balance.Xylo-oligosaccharide is mainly bred
Bifidobacterium, specifically there is obvious proliferation function to bifidobacterium lactis, and suppress the growth and breeding of bacteroid.
Beneficial effects of the present invention are：
Pulvis of the present invention is to be main with the pulvis such as defecation, the celery for nursing one's health enteron aisle and other effects, spinach, black fungus are promoted
Raw material, prebiotic compositions xylo-oligosaccharide, FOS of the addition with regulation gut flora balance, add simultaneously on this basis
Enter hawthorn powder, red date powder, strawberry powder conditioning mouthfeel, its dietary fiber and active component content are high, to human body intestinal canal health, promote
Defecation has the effect of good, while conveniently drinks.
This product composition cleans through ultrasonic wave, and ultrasonic wave cleaning is will be clear by enormous impact force caused by cavitation
What the dirt on the vegetable melon and fruit surface washed hit.The intersection in solid and liquid is very easy to due to this cavitation
Produce, thus there is the vegetable melon and fruit for being put into ultrasonic ozone combination fruit-vegetable cleaner cleaning fluid very strong cleaning to make
With, can kill 99.99% bacterium, destroy chemistry of pesticide key, have more than 95% to highly toxic pesticide such as DDVP, malathions
Thorough degradation rate, moreover it is possible to the heavy metals such as the most cadmium of vegetable surface, copper, lead, arsenic, while ozone caused by use are removed, it is special
If ozone sterilization and degradation of pesticide function, germ can be killed, removes the agricultural chemicals remained on vegetables, the spy with efficient pollution-free
Point, disinfection washing is more thorough, carries out active oxidation decomposition to fruits and vegetables, reaches and eliminate the unusual smell, degrading pesticide, decomposes toxin, disappear
Kill bacterium.
In a word, the present invention adds a variety of prebioticses, can promote gastrointestinal motility mainly using daily veterinary antibiotics as raw material,
The ratio of beneficial bacterium is improved, suppresses harmful bacteria or harmful substance in enteron aisle, immunity is improved, contributes to the health of the mankind, contain
The pulvis of the improvement enteric microorganism of prebiotics can promote the increase of Bifidobacterium and lactobacillus quantity, reduce enterococcal number
Amount, has adjustment effect to enterobacteriaceae quantity, and its prebiotics contained can increase the quantity of beneficial bacterium, and human body is made without secondary
With.
Embodiment
Technical scheme is described in detail with reference to specific embodiment.
Embodiment 1
This contains the dust composition composition of the improvement enteric microorganism of prebiotics, by by weight：Celery powder 70g,
Spinach powder 40g, black fungus powder 20g, hawthorn powder 20g, red date powder 25g, strawberry powder 20g, galactooligosaccharide 20g, different malt are oligomeric
Sugared 20g, FOS 20g, xylo-oligosaccharide 20g.
Preparation method is as follows：Celery, spinach, hawthorn, jujube, strawberry are tentatively cleaned, celery segment, black fungus is through 20 DEG C
Water soaks 4h.Preliminary cleaned raw material is put into ultrasonic ozone combination fruit-vegetable cleaner, cleaned in 60W, 40kHz
30min, drain.Celery after ultrasonic wave is cleaned places -20 DEG C of freezing 1.5h, is crushed immediately.
Black fungus after ultrasonic wave is cleaned, is scalded with boiling water, is placed in baking oven, 50 DEG C of baking 8-10 hours, natural cooling,
Obtain drying black fungus, dried black fungus is used into ultra-fine pulverizer disintegrating 15min, 500 mesh black fungus powders is obtained, is mounted in
It is stand-by in the container of good seal.
Spinach after ultrasonic wave is cleaned drains away the water, and is dried 6 hours at 55 DEG C, natural cooling, by dried spinach
Dish is tentatively crumbed, then is put into 10min in ultra-fine pulverizer disintegrating, obtains 500 mesh spinach powders, is treated in the container of good seal
With.
Hawthorn after ultrasonic wave is cleaned is drained away the water, and is enucleated, and section, is put into baking box, and 80 DEG C are dried 2 hours, then by temperature
Degree is down to 50-60 DEG C and is further continued for drying half an hour, natural cooling in an oven after the time terminates, with ultra-fine pulverizer disintegrating 10min,
300 mesh hawthorn powders are obtained, it is stand-by in the container of good seal.
Jujube after ultrasonic wave is cleaned, drains away the water, and removes jujube core, cuts in half, be put into baking box, and 80 DEG C of bakings 2 are small
When, then cool the temperature to 50-60 DEG C and be further continued for drying half an hour, natural cooling in an oven after the time terminates, it is cool after jujube put
To ultra-fine pulverizer disintegrating 10min, that is, 300 mesh red date powders are obtained, it is stand-by in the container of good seal.
Strawberry stalk after ultrasonic wave is cleaned, is thinly sliced, is put into baking box, and 80 DEG C are dried 2 hours, then cooled the temperature to
50-60 DEG C is further continued for drying half an hour, natural cooling in an oven after the time terminates, it is cool after jujube be put into ultra-fine pulverizer disintegrating
10min, that is, 300 mesh strawberry powders are obtained, it is stand-by in the container of good seal.
Specific preparation process：Method is progressively increased by celery powder 70g, spinach powder 40g, black fungus powder 20g, hawthorn powder using equivalent
20g, red date powder 25g, strawberry powder 20g are well mixed, then sequentially add galactooligosaccharide 20g, isomalto-oligosaccharide 20g,
FOS 20g, xylo-oligosaccharide 20g, it is stirring while adding, after being well mixed, packed using sterileization automated packaging equipment.
From healthy male mice in kunming (Shandong University's Experimental Animal Center), body weight 20-25g.Mouse is randomly divided into
Four groups, every group 20.Mouse experiment is grouped and gavage volume is shown in Table 1.It is 5g to recommend the daily dosage of adult, and mouse dosage is respectively
2 times, 10 times, 20 times of dosage of being grown up.Mouse stomach experiment is carried out, mouse stomach volume is 0.1ml/10g.Continuous gavage two
In week, respectively before to mouse stomach and after gavage last time 24h, aseptic collection stool in mice 0.2-0.4g, determine bifid bar
Bacterium, lactobacillus, enterobacteria, enterococcal quantity.
Experimental result is shown：Enterobacteria, enterococcal quantity are generation significant changes in stool in mice.High dose group
In, bifidobacteria dramatically increases compared with quantity before itself gavage.Middle dose group, lactobacillus quantity contrast in blank group, difference
Significantly.The quantity of lactobacillus either own control in high dose group, or compare with blank group and dramatically increased, its
In contrasted with blank group, difference is extremely notable.Illustrating the dust composition of the present invention has the effect of regulation gut flora.Test number
According to being shown in Table 2.
The mouse experiment of table 1 is grouped and gavage volume
| Experiment packet | Gavage is grouped |
| Control group | 0.1ml/10g physiological saline |
| Low dose group | 0.17g/kg.BW |
| Middle dose group | 0.83g/kg.BW |
| High dose group | 1.67g/kg.BW |
The mouse intestinal flora testing result of table 2 (log cfu/g,)
Note：P1 represents that itself gavage is front and rear relatively in table, and P2 values represent test group compared with control group；* represent that difference shows
Write, * * represent that difference is extremely notable.
Embodiment 2
This contains the dust composition composition of the improvement enteric microorganism of prebiotics, by by weight：Celery powder 60g,
Spinach powder 30g, black fungus powder 15g, hawthorn powder 15g, red date powder 20g, strawberry powder 15g, galactooligosaccharide 15g, different malt are oligomeric
Sugared 15g, FOS 10g, xylo-oligosaccharide 15g.
Preparation method is as follows：Celery, spinach, hawthorn, jujube, strawberry are tentatively cleaned, celery segment, black fungus is through 25 DEG C
Water soaks 3h.Preliminary cleaned raw material is put into ultrasonic ozone combination fruit-vegetable cleaner, cleaned in 60W, 40kHz
30min, drain.Celery after ultrasonic wave is cleaned places -20 DEG C of freezing 1.5h, is crushed immediately.
The preparation method of other components is the same as embodiment 1.
The preparation method of the dust composition：Method is progressively increased by black fungus powder 15g, hawthorn powder 15g, red date powder using equivalent
20g, strawberry powder 15g are well mixed, and then sequentially add galactooligosaccharide 15g, isomalto-oligosaccharide 15g, FOS
10g, xylo-oligosaccharide 15g, it is stirring while adding, after being well mixed, packed using sterileization automated packaging equipment.
To the present invention, existing volunteer trial subject：20-45 year, totally 20, wherein each 10 of men and women, wherein 10 masterpieces
For experimental group, another 10 people as a control group, excludes allergic constitution person, and exclusion has the serious disease such as angiocarpy, liver, kidney and hemopoietic system
Patient.
Dosage and usage：Experimental group personnel 5g for each person every day, is taken, continuous two weeks with 35-40 DEG C of warm water.Control group is not done
Any processing factor.During experiment, experimental group and control group are accustomed to according to daily eating habit and work and rest.
Indexs measure：1. sleep, blood pressure and the stool and urine situation during testing experimental group and control group are observed；②
Hospital is entrusted to carry out blood routine, just routine urinalysis, routine inspection to subject；3. its functional attributes：Subject's fresh excreta is immediately
Censorship.
Number of live bacteria of probiotics is shown in Table 3.
The number of live bacteria of probiotics of table 3 (log cfu/g,N=10)
| Viable bacteria title | Bifidobacterium | Lactobacillus | Enterobacteria | Enterococcus |
| Before taking | 8.04±1.82 | 7.94±1.34 | 7.03±0.75 | 5.63±1.31 |
| After taking | 9.54±2.06 | 8.36±0.72 | 6.91±0.75 | 5.52±1.12 |
Volunteer's safety indexes are shown in Table 4.
The volunteer's safety indexes of table 4
As can be seen from Table 3, after the pulvis of the improvement enteric microorganism containing prebiotics is taken, Bifidobacterium and newborn bar
The quantity of bacterium all has different degrees of increase, and enterobacteria and enterococcus have different degrees of decline, illustrate changing containing prebiotics
The pulvis of kind enteric microorganism has adjustment effect to enterobacteriaceae quantity, and its prebiotics contained can increase the quantity of beneficial bacterium.
As can be seen from Table 4, after volunteer takes the pulvis of the improvement enteric microorganism containing prebiotics, detection knot
Fruit shows that volunteer's safety indexes are free from side effects all in normal range (NR) to human body.
Embodiment 3
This contains the dust composition composition of the improvement enteric microorganism of prebiotics, by by weight：Celery powder 60g,
Spinach powder 30g, black fungus powder 15g, hawthorn powder 15g, red date powder 20g, strawberry powder 15g, galactooligosaccharide 15g, different malt are oligomeric
Sugared 15g, FOS 10g, xylo-oligosaccharide 15g.
Preparation method is as follows：Celery, spinach, hawthorn, jujube, strawberry are tentatively cleaned, celery segment, black fungus is through 15 DEG C
Water soaks 4h.Preliminary cleaned raw material is put into ultrasonic ozone combination fruit-vegetable cleaner, cleaned in 60W, 40kHz
20min, drain.Celery after ultrasonic wave is cleaned places -20 DEG C of freezing 1.5h, is crushed immediately.
Black fungus after ultrasonic wave is cleaned, is scalded with boiling water, is placed in baking oven, 50 DEG C of baking 8-10 hours, natural cooling,
Obtain drying black fungus, dried black fungus is used into ultra-fine pulverizer disintegrating 15min, 500 mesh black fungus powders is obtained, is mounted in
It is stand-by in the container of good seal.
The preparation method of other components is the same as embodiment 1.
Claims (3)
1. a kind of dust composition of the improvement enteric microorganism containing prebiotics, it forms the following originals included by weight
Material：Celery powder 50-70g, spinach powder 20-40g, black fungus powder 10-20g, hawthorn powder 10-20g, red date powder 15-25g, strawberry powder
10-20g, galactooligosaccharide 10-20g, isomalto-oligosaccharide 10-20g, FOS 10-20g, xylo-oligosaccharide 10-20g.
2. the dust composition of the improvement enteric microorganism according to claim 1 containing prebiotics, it is characterised in that its
Form as following raw materials by weight：Celery powder 60g, spinach powder 30g, black fungus powder 15g, hawthorn powder 15g, red date powder 20g,
Strawberry powder 15g, galactooligosaccharide 15g, isomalto-oligosaccharide 15g, FOS 10g, xylo-oligosaccharide 15g.
3. the preparation method of the dust composition of the improvement enteric microorganism containing prebiotics as claimed in claim 1 or 2, tool
Body step is as follows：
（1）Celery, spinach, hawthorn, jujube, strawberry cleaning, celery segment, black fungus are soaked into 3-4h with 15-25 DEG C of water；Will be upper
State ready raw material to be put into ultrasonic ozone combination fruit-vegetable cleaner, 20-40min is cleaned in 60W, 40kHz；
（2）Celery is put into -20 DEG C of freezing 1.5h, crushed immediately, then be placed in ultra-fine pulverizer disintegrating after ultrasonic wave cleans
30min, the celery powder of 500 mesh is obtained, it is stand-by in the container of good seal；
（3）Black fungus after ultrasonic wave is cleaned, is scalded with boiling water, is placed in baking oven, 50 DEG C of baking 8-10 hours, natural cooling,
Obtain drying black fungus, dried black fungus is used into ultra-fine pulverizer disintegrating 15min, 500 mesh black fungus powders is obtained, is mounted in
It is stand-by in the container of good seal；
（4）Spinach after ultrasonic wave is cleaned drains away the water, and is dried 6 hours at 55 DEG C, natural cooling, by dried spinach
Tentatively crumb, then be put into 10min in ultra-fine pulverizer disintegrating, obtain 500 mesh spinach powders, it is stand-by in the container of good seal；
（5）Hawthorn after ultrasonic wave is cleaned is drained away the water, and is enucleated, and section, is put into baking box, and 80 DEG C are dried 2 hours, then by temperature
It is down to 50-60 DEG C to be further continued for drying half an hour, natural cooling in an oven after the time terminates, with ultra-fine pulverizer disintegrating 10min, i.e.,
300 mesh hawthorn powders are obtained, it is stand-by in the container of good seal；
（6）Jujube after ultrasonic wave is cleaned, drains away the water, and removes jujube core, cuts in half, be put into baking box, and 80 DEG C of bakings 2 are small
When, then cool the temperature to 50-60 DEG C and be further continued for drying half an hour, natural cooling in an oven after the time terminates, it is cool after jujube put
To ultra-fine pulverizer disintegrating 10min, that is, 300 mesh red date powders are obtained, it is stand-by in the container of good seal；
（7）Strawberry stalk after ultrasonic wave is cleaned, is thinly sliced, is put into baking box, and 80 DEG C are dried 2 hours, then cooled the temperature to
50-60 DEG C is further continued for drying half an hour, natural cooling in an oven after the time terminates, it is cool after jujube be put into ultra-fine pulverizer disintegrating
10min, that is, 300 mesh strawberry powders are obtained, it is stand-by in the container of good seal；
（8）Method is progressively increased by ready celery powder 50-70g, spinach powder 20-40g, black fungus powder 10-20g, hawthorn using equivalent
Powder 10-20g, red date powder 15-25g, strawberry powder 10-20g are well mixed, and then sequentially add galactooligosaccharide 10-20g, different
Malto-oligosaccharide 10-20g, FOS 10-20g, xylo-oligosaccharide 10-20g, stirring while adding, after being well mixed, use is sterile
Change automated packaging equipment to be packed.
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| CN108813450A (en) * | 2018-05-16 | 2018-11-16 | 浙江省中医药研究院 | A kind of dust composition and preparation method improving enteric microorganism |
| CN111642753A (en) * | 2020-07-17 | 2020-09-11 | 广州同康生物科技有限公司 | Dietary nutrition supplement composition and preparation method thereof |
| CN114105700A (en) * | 2021-11-04 | 2022-03-01 | 济南大学 | Mulching film substitute for strawberry planting and preparation method and application thereof |
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