CN1077122A

CN1077122A - A kind of compound anticancer capsule preparation

Info

Publication number: CN1077122A
Application number: CN 92102701
Authority: CN
Inventors: 张士舜; 陈桂芳
Original assignee: Individual
Current assignee: Individual
Priority date: 1992-04-11
Filing date: 1992-04-11
Publication date: 1993-10-13

Abstract

The present invention relates to a kind of formulation method for the treatment of the compound capsule of cancer, be particularly useful for treating pulmonary carcinoma, colorectal cancer.Compound capsule component of the present invention is made up of Mylabris, Venenum Bufonis, Herba Scutellariae Barbatae, Hedyotidis Diffusae, Herba Solani Lyrati, Radix Ginseng, the Radix Astragali etc., technical processs such as preparation method comprises pulverizing, extraction, concentrates, granulation, through clinical verification, cure and obvious effective rate 12.6%, have no adverse reaction, strengthening vital QI to eliminate pathogenic factors, do not damage resistance of human body, do not damage the human immunity factor.

Description

A kind of compound anticancer capsule preparation

The present invention relates to a kind of compound anticancer capsule preparation method, belong to drug formulation process.

At present, malignant tumor does not worldwide still find the way of better radical cure, the Chemo-Therapy therapy has side effects bigger, and adopting drug matching treatment cancer card great advantage is strengthening vital QI to eliminate pathogenic factors, does not damage the resistance of human body, do not damage the human immunity factor, kill and wound cancerous cell to greatest extent, at present anticancer openly to report more be anticancer " beauty " capsule to Chinese medicine, and this medicine is put into serial production, " beauty " capsule mainly is the treatment esophageal carcinoma, cures obvious effective rate CR+PR=3.2%.

The object of the present invention is to provide a kind of treatment pulmonary carcinoma compound capsule method, the strengthening vital QI to eliminate pathogenic factors that utilizes the medicine active ingredient to produce, heat-clearing and toxic substances removing, blood-activating analgetic, air making-up and spleen enlivening, the functions such as kidney nourishes blood of overflowing reach and delay the cancer diffusion, alleviate slight illness, effectively the purpose of treatment.

Technical scheme of the present invention is achieved in that the composition of the compound medical capsule of this treatment cancer comprises Mylabris 0.05-0.06%, Venenum Bufonis 0.05-0.06%, Herba Scutellariae Barbatae 10-15%, Hedyotidis Diffusae 10-15%, Herba Solani Lyrati 10-15%, Radix Ginseng 2-3%.Radix Astragali 25-30%, Fructus Ligustri Lucidi 20-25%, Moschus 0.1-0.5%, Borneolum Syntheticum 0.05-0.1%, artificial Calculus Bovis 0.9-1.1%, Herba Schizonepetae 5.0-6.0%, Radix Saposhnikoviae 5.0-6.0%.The formulation method that the present invention treats the compound medical capsule of cancer is divided into several parts, at first Mylabris being removed sufficient wing, Semen setariae puts a pot internal heating and sprays water that a little is pasted on the pot to rice, the time cigarette adds Mylabris when emerging, stir-fries with the sallow degree of being of rice gently, takes out and removes the grain of rice, pulverizing, sieving for standby;

With Moschus, artificial Calculus Bovis, Venenum Bufonis, Borneolum Syntheticum, Radix Ginseng, Herba Schizonepetae be developed into fine powder respectively, sieve standby with the Mylabris mixing; Radix Saposhnikoviae elder generation water is moistening, feed superheated steam, volatile oil is distillated through condenser; The Radix Saposhnikoviae medicinal residues that extract volatile oil were extracted 2 hours with the decocting in water that Herba Scutellariae Barbatae, the Radix Astragali, Hedyotidis Diffusae, Herba Solani Lyrati, Fructus Ligustri Lucidi add 10 times of amounts again; the decocting in water that adds for the second time 8 times of amounts extracted 2 hours; filtration, merging filtrate; concentrating under reduced pressure becomes cream, drying, pulverizing to add Moschus, artificial Calculus Bovis, Venenum Bufonis, Borneolum Syntheticum, Radix Ginseng, Herba Schizonepetae, Mylabris fine powder mixing; granulate; spray adds Radix Saposhnikoviae volatile oil, and mixing dress enteric coated capsule promptly.

Compound anti-cancer capsule preparation commodity of the present invention Tai Ji pellet by name is produced by pharmaceutical factory, through Shanghai Institute of Pharmaceutical Industry, the basic non-toxic type medicine of genus of institute of materia medica, Tianjin, Chinese medical courses in general institute resources of medicinal plant toxicity that developmental research is carried out, pharmacological research proof is to S ₁₈₀, HAC, Lemis lung and L ₇₇₁₂Tumor models such as leukemia have than the obvious suppression effect, and obvious effective rate CR+PR=12.6% is cured in clinical practice, and is apparent in view to effects such as pulmonary carcinoma, colorectal cancer, breast carcinoma.

Describe content of the present invention in detail below in conjunction with embodiment.

1, prescription:

Mylabris 1g, Venenum Bufonis 1g, Herba Scutellariae Barbatae 235g, Hedyotidis Diffusae 235g, Herba Solani Lyrati 235g, Radix Ginseng 50g, Radix Astragali 505g, Fructus Ligustri Lucidi 470g, Moschus 2.4g, Borneolum Syntheticum 1.2g, artificial Calculus Bovis 19.2g, Herba Schizonepetae 100g, Radix Saposhnikoviae 1.2g.

2, method for making:

1, Mylabris rice is fried: Mylabris is chosen clean impurity, remove sufficient wing, Semen setariae and put a pot internal heating and spray water that a little is pasted on the pot to rice, add Mylabris when marquis's cigarette is emerged, stir-fry with sallow be the degree of rice gently, the grain of rice is removed in taking-up, pulverizing, sieving for standby;

2, Moschus, artificial Calculus Bovis, Venenum Bufonis, Borneolum Syntheticum, Radix Ginseng, Herba Schizonepetae are ground into fine powder respectively, sieve standby with the Mylabris mixing;

3, Radix Saposhnikoviae elder generation water is moistening, feed superheated steam, volatile oil is distillated through condenser;

4, the Radix Saposhnikoviae medicinal residues that will extract behind the volatile oil extracted 2 hours with the decocting in water that Herba Scutellariae Barbatae, the Radix Astragali, Hedyotidis Diffusae, Herba Solani Lyrati, Fructus Ligustri Lucidi add 10 times of amounts again; the decocting in water that adds for the second time 8 times of amounts extracted 2 hours; filtration, merging filtrate; concentrating under reduced pressure becomes cream, drying, pulverizing to add Moschus, artificial Calculus Bovis, Venenum Bufonis, Borneolum Syntheticum, Radix Ginseng, Herba Schizonepetae, Mylabris fine powder mixing; granulate; spray adds Radix Saposhnikoviae volatile oil, and mixing dress enteric coated capsule promptly.

Claims

1, a kind of compound anticancer capsule preparation, its composition comprises Mylabris 0.05-0.06%, Venenum Bufonis 0.05-0.06%, Herba Scutellariae Barbatae 10-15%, Hedyotidis Diffusae 10-15%, Herba Solani Lyrati 10-15%, Radix Ginseng 2-3%.Radix Astragali 25-30%, Fructus Ligustri Lucidi 20-25%, Moschus 0.1-0.5%, Borneolum Syntheticum 0.05-0.1%, artificial Calculus Bovis 0.9-1.1%, Herba Schizonepetae 5.0-6.0%, Radix Saposhnikoviae 5.0-6.0%.

2, a kind of compound anticancer capsule preparation method is characterized in that Mylabris is removed sufficient wing, Semen setariae puts a pot internal heating and spray water that a little is pasted on the pot to rice, waits when cigarette is emerged to add Mylabris, stir-fry with sallow be the degree of rice gently, and the grain of rice is removed in taking-up, pulverizing, sieving for standby;

With Moschus, artificial Calculus Bovis, Venenum Bufonis, Borneolum Syntheticum, Radix Ginseng, Herba Schizonepetae be ground into fine powder respectively, sieve standby with the Mylabris mixing;

Radix Saposhnikoviae elder generation water is moistening, feed superheated steam, volatile oil is distillated through condenser;

The Radix Saposhnikoviae medicinal residues that extract volatile oil were extracted 2 hours with the decocting in water that Herba Scutellariae Barbatae, the Radix Astragali, Hedyotidis Diffusae, Herba Solani Lyrati, Fructus Ligustri Lucidi add 10 times of amounts again; the decocting in water that adds for the second time 8 times of amounts extracted 2 hours; filtration, merging filtrate; concentrating under reduced pressure becomes cream, drying, pulverizing to add Moschus, artificial Calculus Bovis, Venenum Bufonis, Borneolum Syntheticum, Radix Ginseng, Herba Schizonepetae, Mylabris fine powder mixing; granulate; spray adds Radix Saposhnikoviae volatile oil, and mixing dress enteric coated capsule promptly.