CN1754550B - Compound traditional Chinese medicine glossy ganoderma formulation and preparation method - Google Patents

Compound traditional Chinese medicine glossy ganoderma formulation and preparation method Download PDF

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Publication number
CN1754550B
CN1754550B CN 200410051704 CN200410051704A CN1754550B CN 1754550 B CN1754550 B CN 1754550B CN 200410051704 CN200410051704 CN 200410051704 CN 200410051704 A CN200410051704 A CN 200410051704A CN 1754550 B CN1754550 B CN 1754550B
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China
Prior art keywords
ganoderma
chinese medicine
medicine preparation
radix salviae
salviae miltiorrhizae
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CN 200410051704
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CN1754550A (en
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谢意珍
李森柱
李崇
张智
罗彪
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Guangdong Institute of Microbiology
Guangdong Yuewei Edible Mushroom Technology Co Ltd
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Guangdong Institute of Microbiology
Guangdong Yuewei Edible Mushroom Technology Co Ltd
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Abstract

The invention relates to a compound Chinese medicinal preparation of glossy ganoderma and its preparation, wherein the preparation is prepared from the following raw materials (by weight proportion): glossy ganoderma 20-60, epimedium 10-50, radix salvia miltiorrhiza 10-50, polyporusfrondosus 0-30 and Agaricus blazei Murrill 0-30.

Description

Compound ganoderma Chinese medicine preparation and method for making
[affiliated technical field]
The present invention relates to a kind of compound ganoderma Chinese medicine preparation and method for making, belong to tcm field.
[background technology]
Cancer is one of malignant disease that threatens the human life, does not still have specific medicament and therapy so far.The whole world because of number every year of cancer stricken death more than 5,000,000, the annual new discovery cancer patient of China has more than 160 ten thousand, dead more than 130 ten thousand.Cancer therapy drug occupies important position in world's drug market, effective component extracting is made anticarcinogen the forward position business opportunity is provided for China's Chinese medicine goes to the world from plant.Medicinal fungi is an important component part of natural drug, because of having the advantages that to improve immunity and do not have toxic and side effects, become the important component part of current exploration and excavation cancer therapy drug, and Ganoderma is exactly most widely used a kind of medicinal fungi.Over more than 2,000 year, in Chinese medicine, Ganoderma has been widely used in treating various human diseasess, comprises the disease that inflammation, hypertension, tumor and various dysimmunity cause.
[summary of the invention]
The object of the present invention is to provide a kind of compound ganoderma Chinese medicine preparation, strengthen Ganoderma immunologic function and tumor-inhibiting action, it is big to overcome in the present cancer therapy drug ubiquitous side effect, be easy to generate drug-fast characteristics, be used for ameliorate tumor patient postoperative, the side effect that put, chemotherapy causes and prolong life cycle, the quality of making the life better.
Another object of the present invention provides a kind of method for making of compound ganoderma Chinese medicine preparation.
The basic recipe of Chinese traditional compound medicine of the present invention is to be made by the raw material of following weight proportion (parts by weight): Ganoderma 20~60, Herba Epimedii 10~50, Radix Salviae Miltiorrhizae 10~50, Grifola frondosa 0~30, Agaricus blazei Murrill 0~30.
Chinese medicine preparation of the present invention can be made powder, thick paste, tablet, oral liquid or capsule etc. with the raw material of above-mentioned weight proportion (parts by weight).
The method for making of above-mentioned Chinese traditional compound medicine is: relevant composition is extracted 1~3 time with 5~15 times of 100 ℃ of hot water extraction or decompression, and each 1~3 hour, merge extractive liquid, was handled extracting solution on demand.
After said extracted liquid filters filtrate is concentrated, fill becomes oral liquid or further is condensed into thick paste, is spray dried to powder.
Or filtrate filtered is carried out high speed centrifugation, and (10000~20000 change/min), filtrate are concentrated, and fill becomes oral liquid or further is condensed into thick paste, is spray dried to powder.
The another kind of method for making of above-mentioned Chinese traditional compound medicine is: with 5~15 times of 40~80% medicinal alcohol, jacketed pan reflux 1-3 hour merges backflow with relevant composition, filters back reclaim under reduced pressure ethanol.Backflow is condensed into fluid extract, or further adds appropriate amount of starch, the pelletize of sieving behind the mix homogeneously is made tablet or is incapsulated.
The present invention is by with Chinese medicine reasonable compatibilities such as Ganoderma and Radix Salviae Miltiorrhizae, Herba Epimedii, having strengthened Ganoderma improves immune function, suppresses the growth of tumour cell ability, overcome in the present cancer therapy drug ubiquitous side effect big, be easy to generate drug-fast characteristics, simultaneously, because the adding of Radix Salviae Miltiorrhizae and Herba Epimedii, make this medicine have again and improve the effect of sleeping, supporting the kidney hepatoprotective, and to tumor patient because the operation, side effect such as the alopecia that put, the chemotherapy effect causes, inappetence, insomnia, lassitude have good improvement effect.
[specific embodiment]
Embodiment 1:
Ganoderma 50kg, Herba Epimedii 25kg, Radix Salviae Miltiorrhizae 25kg adds 10 times of water, puts into jacketed pan, feeds and is steam heated to 100 ℃, extracts twice, and each 2 hours, the cloth bag filtration.Merge and filter the back extracting solution, be concentrated into thick paste, be spray dried to powder.
Embodiment 2:
Ganoderma 50kg, Herba Epimedii 25kg, Radix Salviae Miltiorrhizae 25kg adds 10 times of water, puts into jacketed pan, feeds and is steam heated to 100 ℃, extracts twice, and each 2 hours, the cloth bag filtration.Merge and filter the back extracting solution, carry out high speed centrifugation with 15000 commentaries on classics/min.Filtrate is concentrated into thick paste, is spray dried to powder.
Embodiment 3:
Ganoderma 50kg, Herba Epimedii 25kg, Radix Salviae Miltiorrhizae 25kg adds 10 times of water, the 100 ℃ of hot water extraction or the extraction twice of reducing pressure, each 2 hours, merge extractive liquid, was further behind 15000 commentaries on classics/min high speed centrifugations, be concentrated into 200kg, add an amount of fructose or Mel, fill becomes oral liquid.
Embodiment 4:
Ganoderma 40kg, Herba Epimedii 30kg, Radix Salviae Miltiorrhizae 30kg adds 10 times of water, the 100 ℃ of hot water extraction or the extraction twice of reducing pressure, each 2 hours, merge extractive liquid, was spray dried to powder after concentrating.
Embodiment 5:
Ganoderma 30kg, Herba Epimedii 30kg, Radix Salviae Miltiorrhizae 30kg adds 10 times of water, the 100 ℃ of hot water extraction or the extraction twice of reducing pressure, each 2 hours, merge extractive liquid, was spray dried to powder after concentrating.
Embodiment 6:
Ganoderma 30kg, Herba Epimedii 25kg, Radix Salviae Miltiorrhizae 25kg, Grifola frondosa 10kg, Agaricus blazei Murrill 10kg adds 10 times of water, the 100 ℃ of hot water extraction or the extraction twice of reducing pressure, each 2 hours, merge extractive liquid, was spray dried to powder after concentrating.
Embodiment 7:
Ganoderma 30kg, Herba Epimedii 25kg, Radix Salviae Miltiorrhizae 25kg, Grifola frondosa 10kg, Agaricus blazei Murrill 10kg, the medicinal alcohol of 6 times of 70% concentration of adding, jacketed pan opposing steam flow 2 hours merges backflow, and reclaim under reduced pressure ethanol further is condensed into fluid extract with extracting solution.

Claims (8)

1. compound ganoderma Chinese medicine preparation is characterized in that it is made by following materials of weight proportions medicine: Ganoderma 20~60, Herba Epimedii 10~50, Radix Salviae Miltiorrhizae 10~50, Grifola frondosa 0~30, Agaricus blazei Murrill 0~30.
2. the described compound ganoderma Chinese medicine preparation of claim 1 is characterized in that it is made by following materials of weight proportions medicine: Ganoderma 50, Herba Epimedii 25, Radix Salviae Miltiorrhizae 25.
3. the described compound ganoderma Chinese medicine preparation of claim 1 is characterized in that it is made by following materials of weight proportions medicine: Ganoderma 40, Herba Epimedii 30, Radix Salviae Miltiorrhizae 30.
4. the described compound ganoderma Chinese medicine preparation of claim 1 is characterized in that it is made by following materials of weight proportions medicine: Ganoderma 30, Herba Epimedii 30, Radix Salviae Miltiorrhizae 30.
5. the described compound ganoderma Chinese medicine preparation of claim 1 is characterized in that it is made by following materials of weight proportions medicine: Ganoderma 30, Herba Epimedii 25, Radix Salviae Miltiorrhizae 25, Grifola frondosa 10, Agaricus blazei Murrill 10.
6. the method for making of the described Chinese medicine preparation of one of claim 1-5 is characterized in that crude drug is extracted 1-3 time with 5~15 times of 100 ℃ of hot water extraction or decompression, and each 1-3 hour, merge extractive liquid, was handled extracting solution on demand.
7. the method for making of the described Chinese medicine preparation of claim 6 is characterized in that extracting solution behind 10000~20000 commentaries on classics/min high speed centrifugations, concentrates, and fill is oral liquid or further concentrates, is spray dried to powder.
8. another method for making of the described Chinese medicine preparation of one of claim 1-5, it is characterized in that crude drug with 5~15 times of 40~80% medicinal alcohol, jacketed pan heating and refluxing extraction 1-3 hour, merge backflow, filter back reclaim under reduced pressure ethanol, backflow is condensed into fluid extract, or further adds appropriate amount of starch, the pelletize of sieving behind the mix homogeneously is made tablet or is incapsulated.
CN 200410051704 2004-09-30 2004-09-30 Compound traditional Chinese medicine glossy ganoderma formulation and preparation method Active CN1754550B (en)

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103610059A (en) * 2013-11-28 2014-03-05 潘新华 Lucid ganoderma oral solution
CN110585268A (en) * 2019-09-18 2019-12-20 广东粤微生物科技有限公司 Composition for improving male endurance and energy vitality as well as preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1118263A (en) * 1994-09-06 1996-03-13 毕盛 Life star-Chinese medicine for cancers
CN1444983A (en) * 2003-03-18 2003-10-01 李新民 Ankangxin capsule

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1118263A (en) * 1994-09-06 1996-03-13 毕盛 Life star-Chinese medicine for cancers
CN1444983A (en) * 2003-03-18 2003-10-01 李新民 Ankangxin capsule

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