CN107596247A - A kind of anaesthetic and its manufacturing process for treating tuberculosis - Google Patents

A kind of anaesthetic and its manufacturing process for treating tuberculosis Download PDF

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CN107596247A
CN107596247A CN201710988654.3A CN201710988654A CN107596247A CN 107596247 A CN107596247 A CN 107596247A CN 201710988654 A CN201710988654 A CN 201710988654A CN 107596247 A CN107596247 A CN 107596247A
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parts
anaesthetic
tuberculosis
acid
oil
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CN107596247B (en
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AFFILIATED HOSPITAL OF INNER MONGOLIA UNIVERSITY FOR NATIONALITIES
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Abstract

The present invention relates to a kind of medicine and its manufacturing process, i.e., a kind of anaesthetic and its manufacturing process for treating tuberculosis, it is characterized in:The anaesthetic includes the bulk drug of following parts by weight:2-18 parts of copper spin-off, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate; 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil; 1-3 parts of caryophyllus oil, 1-3 parts of linaloe oil, 1-3 parts of carthamin; 2-5 parts of dimethoxycoumarin, 0.5-1 part of iridin, 1-3 parts of myrobalan's tannic acid; 16-24 parts of cardamom, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG; 8-12 parts of calculus bovis factitius, 1-2 parts of muscone.The beneficial effects of the invention are as follows:With clearing heat and detoxicating, benefit lung and restrain cough resolve phlegm effect, there is significant curative effect to diseases such as cough ant phlegm, chest pulmonary abscess, tuberculosis or even lung cancer, and toxic side effect is very low, the crowd of being applicable scope is wide, is easy to take, is easy to digest and assimilate, markedly fast, it is expected to as the typical medicaments of pneumotherapy.

Description

A kind of anaesthetic and its manufacturing process for treating tuberculosis
Technical field
The present invention relates to a kind of medicine and preparation method, i.e., a kind of anaesthetic and its manufacturing process for treating tuberculosis.
Background technology
Tuberculosis refers mainly to the pulmonary lesions such as cough ant phlegm, chest pulmonary abscess, tuberculosis or even lung cancer.Modern medicine is referred to as lung Inflammation, pulmonary tuberculosis, occupying lesion etc., Mongolian medicine have abundant Couple herbs to such disease, there is a variety of effective illiteracies Prescription agent.But above-mentioned anaesthetic is more to be spread in the form of proved recipe among the people, some has been on the verge of lost, and some through encrypting repeatedly Changed beyond recognition, some bulk drug scarcity of resources or disabled, cause compatibility to differ in addition, and mechanism is unknown, and drug effect is unstable, Limit the application of clinic.The processing method of above-mentioned anaesthetic is more ancient, more using powder processed life with etc. mode be used as medicine, dosage is big, Difficulty is taken, some also has toxic side effect.Therefore, it is badly in need of carrying out research arrangement to the anaesthetic of existing treatment tuberculosis, finds treatment Effect is definite, have no toxic side effect, medicine source is sufficient, the Prescription of Mongolian Medicine that preparation method is advanced, convenient to take.
The content of the invention
The purpose of the present invention is to find a kind of to have the pulmonary lesions such as cough ant phlegm, chest pulmonary abscess, tuberculosis or even lung cancer Significant curative effect, and toxic side effect is low or fogless toxic side effect, medicine source are sufficient, the anaesthetic that preparation method is advanced, convenient to take and its manufacture Technique.
Above-mentioned purpose is realized by following technical scheme:A kind of anaesthetic for treating tuberculosis, is characterized in:The treatment lung The anaesthetic of disease includes the bulk drug of following parts by weight:2-18 parts of copper spin-off, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate are aqueous 2-5 parts of calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of caryophyllus oil, 1-3 parts of linaloe oil, carthamin 1-3 Part, 2-5 parts of dimethoxycoumarin, 0.5-1 part of iridin, 1-3 parts of myrobalan's tannic acid, 16-24 parts of cardamom, radix glehniae 8-12 Part, 8-12 parts of HEIYUNXIANG, 8-12 parts of calculus bovis factitius, 1-2 parts of muscone.
2-18 parts of the copper spin-off is copper ash(System)12-18 parts or 2-3 parts of 2-4 parts of verdigris or blue stone.
2-5 parts of the calcium carbonate, 2-5 parts of calcium phosphate, 40-60 parts with artiodactyl angle of 2-5 parts of amino acid substitute.
40-60 parts of the artiodactyl angle includes 8-12 parts of PULVIS CORNUS BUBALI CONCEN TRATUS, 8-12 parts of antelope's horn, deer horn 8-12 One of part, 18-22 parts of ox horn, 8-12 parts of pilose antler or two kinds and two or more.
16-24 parts of the cardamom is 8-12 parts of 8-12 parts of Amomum cardamomum and nutmeg.
The bulk drug sandalwood oil, caryophyllus oil, linaloe oil, carthamin, dimethoxycoumarin, iridin, myrobalan's tannic acid point Do not substituted by following bulk drug:The sandalwood oil is by 8-12 parts of 8-12 parts of Santalum album, santal replacements;The caryophyllus oil is by fourth Fragrant 8-12 parts of replacements;The iridin by 8-12 parts of 8-12 parts of iris or blackberry lily or 8-12 parts of elegant jessamine or fringed iris 8- 12 parts of replacements;The calcium sulfate 8-12 parts of replacements of gypsum;The dimethoxycoumarin is with 8-12 parts of artemisia scoparia or oriental wormwood 8-12 Part substitutes;Myrobalan's tannic acid is by 8-12 parts of replacements of myrobalan;The linaloe oil 8-12 parts of replacements of agalloch eaglewood;The carthamin is used 8-12 parts of replacements of safflower.
The bulk drug adds 8-12 parts of tsaoko, 8-12 parts of adder-wort, 8-12 parts of the tuber of dwarf lilyturf, 8-12 parts of fragrant plantain lily flower, white lettuce 8-12 parts of victory.
The antelope's horn, deer horn, the processing method of ox horn are with after the immersion of 75% ethanol or steam disinfection, are ground into fine powder. Add 10 times of weight waters to decoct twice, 7~10 hours every time, supplement the moisture boiled off, collecting decoction, filter in decoction process at any time Cross, filtrate is concentrated into 1-the 5% of original weight amount, after being dried below 80 DEG C, is ground into fine powder, sieves, produces.With other bulk drugs Mixing, the formulations such as ball, scattered, cream or capsule are made.
The cardamom, radix glehniae, HEIYUNXIANG, Santalum album, santal, cloves, iris, blackberry lily, elegant jessamine, fringed iris, shore Wormwood artemisia, oriental wormwood, myrobalan, agalloch eaglewood, safflower, tsaoko, adder-wort, the tuber of dwarf lilyturf, fragrant plantain lily flower, white lettuce victory are beaten powder and crossed more than 60 mesh and sieve, with other Bulk drug mixes, and the formulations such as ball, scattered, cream or capsule are made.
The cardamom, radix glehniae, HEIYUNXIANG, Santalum album, santal, cloves, iris, blackberry lily, elegant jessamine, fringed iris, shore Wormwood artemisia, oriental wormwood, myrobalan, agalloch eaglewood, safflower, tsaoko, adder-wort, the tuber of dwarf lilyturf, fragrant plantain lily flower, white lettuce victory are beaten powder and crossed more than 80 mesh and sieve, after mixing With more than 70% alcohol steep 30-60 minutes, ethanol is recovered under reduced pressure;Extracted 30-60 minutes with ethyl acetate again, recovery is molten Crushing is concentrated to dryness after agent, crosses more than 60 mesh and sieves, mixed with other bulk drugs, the formulations such as ball, scattered, cream or capsule are made.
The beneficial effects of the invention are as follows:With clearing heat and detoxicating, benefit lung and restrain cough resolve phlegm effect, to cough ant phlegm, chest pulmonary abscess, The disease such as tuberculosis or even lung cancer has significant curative effect, and toxic side effect is very low, and applicable crowd's scope is wide, is easy to take, is easy to digest Absorb, markedly fast, it is expected to as the typical medicaments of pneumotherapy.
Embodiment
The first embodiment:
A kind of anaesthetic for treating tuberculosis is developed, includes the bulk drug of following parts by weight:2-18 parts of copper spin-off, calcium carbonate 2-5 Part, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of caryophyllus oil, agalloch eaglewood 1-3 parts of oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of iridin, 1-3 parts of myrobalan's tannic acid, cardamom 16-24 parts, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, 8-12 parts of calculus bovis factitius, 1-2 parts of muscone.
Cardamom, radix glehniae, HEIYUNXIANG beaten powder crossed more than 60 mesh and sieve, mixed with other bulk drugs, be made ball, dissipate, cream or The formulations such as capsule.
Instructions of taking:Adult 1.5-2g/ times, takes 2-3 day.
Here copper spin-off is the broad sense oxide of metallic copper, can there is the product of a variety of micro mist shapes.Bronze, brass or copper ware is Mongolia Race's conventional cutlery, copper are also one of indispensable nutriment of human body, and copper is used as medicine has therapeutic action to a variety of diseases, There is the effect of definite especially for tuberculosis.The mode of copper similar drug is a lot, and this example is recommended using copper ash(System), can also adopt With verdigris or blue stone.
The copper ash is the traditional medicine of Mongolian medicine, the thin layer that mostly bronze, brass or copper ware manufacturing process high temperature is forged and come off, also may be used So that metallic copper is red through forging, wafer thin or filings are pounded into, sea-buckthorn soup boils, and dries, then grinds, stewing forges altogether with Sulfur, borax, sesame After apply.Processed product custom claims copper ash to be also known as red copper ash, the slow element of entitled wise this sound crow of Mongolia.Copper ash function for " dry purulence, The heat of clearing lung-heat liver ", available for diseases such as treatment lung heat, hepatapostema, pulmonary tuberculosis, cough purulence, hemoptysis.This example is used as medicine with 12-18 parts, is faced Bed is evident in efficacy.
The verdigris is also referred to as copper green, is oxidized after copper makes moist in atmosphere, the green basic copper carbonate that surface is given birth to.It is ancient When, verdigris is the rust of copper, and the rust for accelerating its generation green on copper can be sprayed on vinegar, scrapes and produces.Verdigris is bitter in taste, sour, puckery, It is cold.It is poisonous.With detoxifying, remove rotten, desinsection and other effects.This product makees externally applied drug because poisonous more, controls nose Xi meat, eyelid is rotten to the corn, sore Ulcer stubborn dermatitis etc..For oral administration be often incorporated in corresponding prescription treats wind phlegm to suffer from, fainted suddenly and the diseases such as vim and vigour are pained, each dosage of being grown up It is limited within 5g.This example is used as medicine with 2-4 parts, and maximum ratio is only 8%, is 160mg/ times according to 2g/ calculating of dosage, Belong to safe dose, and be suitable to short-term medication patient.
Blue stone, English name Copper (II) sulfate pentahydrate, molecular formula CUSO45H2O, Chinese Title Salzburg vitriol, Chinese nickname blue vitriol, blue stone, lapis divinus, copper sulphate, cupric sulfate pentahydrate (medicinal), copper sulphate (feed Level).Belong to the emetic drug in Chinese medicine.It is cold in nature;It is sour, pungent;Return liver, gallbladder channel.Function vomiting phlegmatic savliva, detoxify hygroscopic, corrosion sore of dispelling.It is main Control wind phlegm to be jammed, larynx numbness, epilepsy, eat poisonous substance by mistake, the eye of wind is red rotten, aphtha, the disease such as noma.Because its is toxic, wrongly take, excess Cause poisoning.Adult is for oral administration every time to be less than 300mg.This example is used as medicine for 2-3 parts with blue stone, and maximum ratio is only 6%, according to dosage 2g/ calculating, is 120mg/ times, belongs to safe dose, and be suitable to short-term medication patient.
Calcium carbonate Calcium carbonate, molecular formula:CaCO3.Precipitated calcium carbonate can be used as leavening agent, flour processing Agent, anticaking agent, acidity regulator, nutrition fortifier, curing agent etc..China provides to can be used for the varieties of food items that need to add swelling agent And chewing gum base, by GMP.Flour improver is can also be used for, maximum usage amount is 0.03%;7.5~18g/kg of milk powder;Soymilk Powder, 4~20g/kg of bean powder;0.4~3.4g/kg of soft drink;6~8g/kg of lotus root starch;2~7g/kg of instant breakfast cereal products.FDA (184.1192,2000)Being limited property does not provide, by GMP.It is more when this product makees leavening agent use to be used cooperatively with other kinds, with The leavening agent that the compoundings such as sodium acid carbonate, alum obtain, heat then slowly disengage carbon dioxide, produce food uniform, fine and smooth Bulk body, the quality of cake, bread, biscuit can be improved.In addition with the effect for strengthening calcium, the smaller easier suction of calcium carbonate granule Receive.In Japan, precipitated calcium carbonate is used as leavening agent, and dosage is 1% in normal food.Can also be used as feed nutrition hardening agent.Carbon Sour calcium is the main component of anaesthetic calcite, has clear bar up to xeothermic, antiemetic, antidiarrheal, help digestion, detoxify, broken ruffian, callus, synthetism Adjust member and other effects.
Calcium phosphate calcium phosphate, tribasic, molecular formula (Ca3 (PO4) 2), insoluble in ethanol and acetone, Water is slightly soluble in, is soluble in watery hydrochloric acid and nitric acid.It may be used as anticaking agent, acidity regulator, nutritional supplement, fumet, stably Agent, water retention agent.It is used as anticaking agent, acidity regulator, nutritional supplement, fumet, stabilizer, moisture in the food industry Retention agent.China《Food additives use sanitary standard》(GB2760-2011) provide:Calcium phosphate can be used for wheat flour, maximum Usage amount is 0.03g/kg;Solid beverage 8.0g/kg;Potato chips 2.0g/kg.It can be used for as water retention agent in flour. FAO/WHO is provided:As anticaking agent can be used for glucose powder, cane sugar powder, research on maximum utilized quantity be 15g/kg (individually or with other anticaking agents Share, in the absence of starch);Milk powder, dry cream, (shared individually or with other stabilizers, in terms of anhydride) for 5g/kg;For During automatic vending machine, milk powder, 10g/kg, dry cream 1g/kg (are shared individually or with other anticaking agents);Soup and custard, 15mg/kg (sharing individually or with stearate and silica, refer to dehydrating prods);Cocoa power and containing sugared cocoa power, 10g/kg (individually or Shared with other anticaking agents, automatic vending machine is only used for containing sugared cocoa power).As stabilizer etc. can be used for evaporated milk, condensed milk, Dilute cream, dosage is 2g/kg (alone), 3g/kg (being shared with other stabilizers), in terms of anhydride.It is for processing cheese 9g/kg (total phosphate, in terms of phosphorus).This product is still used as calcium constituent hardening agent, and for biscuit, bread etc., its dosage is to cereal Powder is 3g/kg, solid beverage 20g/kg, in terms of element calcium.Calcium phosphate is the animals such as Mongolian medicine's conventional crude drugs deer, ox, sheep, pig The main component of bone, have detoxify, calm the nerves, be anticonvulsion, strengthening body etc. acts on.
Hydrous calcium sulfate(CaSO4·2H2O), it is cool in nature, there is the effect of clearing heat and detoxicating.Can be cleared away heart-fire lung, control agitation, let out it is hot and suffocating, It is only dry thirsty, control fanatical, fire is coughed, and receives hot sweat, and disappear hot phlegm, firmly nosebleed epistaxis, adjusts aphtha, is managed pharyngalgia, promoting lactation, flat acute mastitis, Xie Huozhuo, is treated Metal-inflicted wound.Control and have a headache and fever, the long screen of blurred vision, toothache, desinsection, diuresis.
The amino acid (amino acid) is the common name of a kind of organic compound containing amino and carboxyl, macromolecular egg The basic composition unit of white matter, it is the base substance for forming protein needed for Animal nutrition.The species of amino acid is a lot, this example institute State amino acid include lysine, alanine, arginine, aspartic acid, cystine, leucine, proline, tyrosine, histidine, Valine.
Sandalwood oil, English name:Sandalwood Oil, latin name Santalum album L, it is sandalwood plants wingceltis Volatile oil of the fragrant heartwood through distillation gained, wherein santalol containing A and β-santalol (α-, β-Santalol) 90% with On, powerful antibacterial action is respectively provided with, once as urethra disinfectant.Be used as medicine bitter, warm-natured, returns stomach, kidney channel, have drop it is inverse and The effect of stomach, promoting qi circulation and relieving pain, gonorrhoea of stopping, swollen heat that disappears.It is usually used in cure hiccup, vomiting, epigastric pain, pain in the back, nephralgia, trusted subordinate's pain Bitterly.Modern study finds that sandalwood oil can suppress the growth of staphylococcus aureus in urinary tract, improves the difficult symptom of urine.To dysentery Shigella, mycobacterium tuberculosis have inhibitory action.
Caryophyllus oil is dicotyledon plant clove of myrtaceae(Eugenia caryophyllata)Dry flower (Cloves)Volatile oil through distillation gained, mainly contains Eugenol (Eugenol), acetyleugenol, B- carypohyllenes (B mono- ), and methyl-n-amyl ketone, gaultherolin, Humuleno (Humuleno), benzaldehyde, benzylalcohol, a first Caryophyllene Epoxide benzaldehyde, benzyl acetate, chavicol (Chavicol), ylangenes of a mono- (Ylangene of a mono-) etc..It is used as medicine acrid-sweet flavor, property is big Heat, enter stomach kidney two warp, there is middle benefit gas, warm up kidney, drop the effect of inverse.It is usually used in controlling hiccup, vomits, gastric disorder causing nausea, rush down dysentery, trusted subordinate's crymodynia, Xuan addictions, hernia, tinea etc..It is used for the skin trauma of sore, carbuncle, malignant boil, furuncle etc. after dilution, there is functions of detumescence, relieving inflammation, promotes the effect of healing.
Linaloe oil, volatile oil contained by agalloch eaglewood, wherein containing benzylacetone, to methoxybenzyl benzylacetone, hydrocinnamic acid, to first Epoxide hydrocinnamic acid, agarospirol(Agaro- spirol), linalool(Agarol), agarofuran(Agarofuran), two Hydrogen agarofuran, 4-Hydroxydihydroagarofuran, 3,4- dihydroxy dihydroagarofuran, Nor-Ketoagarofuran(Nor- ketoaga- rofuran)Deng.The study find that linaloe oil is the main active of agalloch eaglewood, except with the original of agalloch eaglewood Outside drug effect, there is the effect of obvious to pulmonary lesions such as cough ant phlegm, chest pulmonary abscess, tuberculosis or even lung cancer.
Carthamin (class of Chinese medicine II, freeze-dried) is a kind of water-soluble flavone class compound extracted from safflower, pharmacodynamics Documents and materials are reported:Safflower has reduction coronary resistance, increases the effect of coronary flow and myocardial nutrition.Carthamin can reduce rabbit reality The scope and degree of myocardial inyaretion are tested, improves damage and necrotic type ECG Change.Pharmacodynamic study shows, carthamin 7- 28mg/kg can significantly inhibit the rise of dog arteria coroaria sinistra caused by ligature EECG ST sections, reduce the release of serum acid kinase, contracting Myocardial infarct area.Carthamin has obvious effect to Rat Experimental thrombosis and platelet aggregation.
Dimethoxycoumarin, English name Scoparone, have relieving asthma, antibechic, phlegm-dispelling functions.Suitable for treating branch gas Pipe asthma and sample bronchitis of panting, it is especially preferable to senile bronchial astehma curative effect;It is athero- hard to be also applied for coronary artery The property changed heart disease(Coronary heart disease), angina pectoris and arrhythmia cordis etc..
Iridin, English name Tectoridin, molecular formula C22H22O11, energy heat-clearing poison, detumescence pain, it is usually used in experiencing wind-heat, Or phlegm heat stops up the abscess of throat caused by containing, constipation and anuresis, larynx numbness is obstructed, cough and asthma, belly ponding, and skin blacks, and cloudy hernia swells Thorn, acute mastitis is from the beginning of grade disease.
Myrobalan's tannic acid, English name Tannic acid, Chinese nickname:Myrobalan's tannic acid;Myrobalani-tannin;Myrobalani-tannin;Terminalia chebula Diphenic acid;Myrobalan's woods tannin, molecular formula C76H52O46, its composition are Chebulagic acid(Chebulagic acid), chebulinic acid (Chebulinic acid), terchebin(Terchebin), corilagin(Corilagin), glucogallin (Glucogallin), gallic acid(Ellagic acid), 1,3,6- trigalloylglucoses and 1,2,3,4,6- five do not eat The such as sub- acyl glucose still containing shikimic acid, dehydroshikimis acid, quininic acid, arabinose, fructose, glucose, sucrose, rhamnose and Amino acid also contains Sennoside A(Sennoside A), terchebin(Chebulin), tannase(Tannase), polyphenol oxidase (Polyphenol oxidase), peroxidase and ascorbic acid oxidase etc..With astringing the lung, puckery intestines, a variety of work(such as lower gas Effect.Chronic cough aphonia is controlled, chronic diarrhea, protracted dysentery, prolapse of the anus, is had blood in stool, uterine bleeding, with, seminal emission, frequent micturition.
Cardamom, English name Jave Amonum Fruit, latin name:Alpinia katsumadai Hayat[Languas Katsumadai (Hayata) Merr.], have in one's early teens, Amomum cardamomum, Galanga Galangal Seed etc. it is a variety of, separately have the similar kind such as nutmeg.This Example recommends to use Amomum cardamomum and nutmeg.Amomum cardamomum is zingiberaceous plant Amomum cardamomum Amomum kravanh Pierre ex Gagnep or amomum compactum Soland ex Maton Amomum compactum Soland ex Maton dry mature fruit.Nature and flavor:It is pungent, heat. Return lung warp, the spleen channel, stomach.Function:Cold dispelling eliminating dampness, relieving alcoholism, dampness elimination disappear ruffian, promoting the circulation of qi middle benefit gas, appetite-stimulating indigestion-relieving.Cure mainly:It is wet it is turbid in Resistance, do not feel like eating, damp-warm syndrome is from the beginning of uncomfortable in chest not hungry, cold-dampness is vomitted inverse, chest and abdomen swelling and pain, dyspepsia.Nutmeg, scientific name Myristica Fragrans, it is the benevolence of Myristica aiphyllium plant, void can be controlled and rush down cold dysentery, coldness and pain in the epigastrium, vomiting etc., external application can post Infested expellent, treatment rheumatalgia etc..
Radix glehniae is that samphire glehnia littoralis (Glehnia lit-toralis F.Schmidt ex Miq.) is entered with root Medicine.Alias glehniae,radix, glehniae,radix, silver-colored the root of straight ladybell, RADIX GLEHNIAE from Liaoning of China, Soviet Union's bar ginseng, bar ginseng, RADIX GLEHNIAE.Containing Imperatorin (imperatorin), psoralen(psoralen), bergapten, circle angelica lactone -7-0- β-gentiobioside (oosthenol-7-0-β-gentio-bioside)Etc. a variety of cumarins, and containing alkaloid, starch, trace volatile oil etc..North The sweet sweet tea of the root of straight ladybell, is clinical conventional drugs for nourishing yin, nourishiing yin to clear away the lung-heat, expelling phlegm and arresting coughing.Cure mainly dryness of the lung dry cough, consumption of body fluid caused by febrile disease, thirsty etc. Disease.
HEIYUNXIANG is the dry of olive subject plant Mu Ku fruit myrrh Resin Commiphorae muakulis (Guggulum) Dry resin, contain stearic acid, stigmast-4-ene-3,6-dione, cupreol, 6 β-hydroxystigmast-4-ene- 3-one, 2 β, 20 (s)-dihydroxydammar-24-ene-3-one, daucosterol, isolariciresinol.It is used as medicine bitter, property It is cool, gas is fragrant, there is swelling and pain relieving, callus and other effects, for measles, smallpox, scarlet fever, anthrax, hemiplegia, liver heat, bone Folding, brain shouting pain etc..Modern pharmacology research proves that HEIYUNXIANG can reduce cholesterol in serum, phosphatide and triglycerides, first shape Gland activation, and the effect such as have significant anti-inflammatory, antibacterial antitumor of composition in HEIYUNXIANG.
Calculus bovis factitius is the artifact of natural ox gallstone, and cow-bezoar Bos taurus domesticus Gmelin are called west It is yellow, rhinoceros is yellow, ugly treasured, be the gall stone of Chordata Mammalia bovid cattle liver.Containing cholic acid 5% -11%, deoxycholic aicd About 2%, chenodeoxycholic acid 0.6% -1.7% and its esters, bilirubin (bilirubin) and its calcium salt, and containing cholesterine, ergot steroid Alcohol, lecithin, aliphatic acid, vitamin D, water-soluble peptide constituents SMC, Yi Jitong, iron, magnesium, zinc etc..Australia's production cow-bezoar contains Carotenoid, alanine, glycine, taurine (taurine), asparatate, arginine, leucine, methionine etc. are a variety of Amino acid.Traditional Chinese medicine thinks cow-bezoar gas delicate fragrance, mildly bitter flavor then sweet tea, cool in nature.Available for heat-clearing, removing toxic substances, arresting convulsion.Internal treatment of high fever Abscess of throat, aphtha carbuncle swells, uremia etc. are controlled in the disease such as delirious, demented, child convulsion, twitch, external application.
Muscone is the Synthetic artifact of natural musk.Moschus Moschus, also known as very little fragrant, member cun, when the door, smelly son, Fragrant navel.For animal in deer family woods musk deer Moschus berezovskii Flerov. horses musk deer M. sifanicusPrzewalski or Drying secretion in former musk deer M.moschiferus L. hero body note capsules.Containing muskone(Muscone), normuscone (Normuscone), 3-methylcyclopentadecanol(Muscol), Moschus pyrans(Mus- copyran), muscopyridine(Muscopyridine), hydroxyl Base muscopyridine-A(Hydroxymuscopyridine A), hydroxyl muscopyridine-B(Hydroxymuscopyridine B)、 3- methyl cyclotridecanones(3-Me- thylcyclotridecan-1-one), ring tetradecane ketone(Cyclotetrade- can-1- one)Deng.Also the 3- of Gona-4-en-3-one containing courage ketone(Cholest-4-ene-3- one), cholesterine and its esters, stosterone (Testosterone), female ethanol(Estradiol), 5 α-androstane -3,17- diketone(5α-Androstan-3,17-dione)Deng 11 kinds of androstane derivatives.Still contain protein and amino acids, contain in Moschus in the Moschus of protein about 25%. and find a kind of molecular weight For 1000 or so peptides active material, and a kind of polypeptide of molecular weight about 5000~6000 is isolated, 4 are contained in its alcohol soluble substance Kind free amino acid, i.e. arginine, proline, glycine and alanine extract alcohol soluble substance acetone, methanol and water, hydrolysis Amino acid analysis afterwards shows:Amino acid content highest in methanolic extract, wherein with asparatate, serine, cystine Equal size highest;Acetone extract Glutamic Acid, valine, histidine and glycine are higher.In addition, in Moschus also containing potassium, sodium, Calcium, magnesium, aluminium, lead, chlorine, sulfate, phosphate and ammonium carbonate and allantoin(Allantoin), urea, cellulose etc..Moschus Ketone is important active ingredient, its content account in natural musk meat 1.58%~1.84%, 0.90% accounted in natural musk hair shell ~3.08%, have been able to now artificial synthesized.Nature and flavor are pungent, temperature.Enter the heart, spleen, Liver Channel.And have one's ideas straightened out, invigorate blood circulation, dissipating bind, analgesic etc. Multiple efficacies.《Herbal steel wood》Carry " lead to all keys, open channels and collaterals, saturating flesh bone, relieving alcoholism, disappear melon and fruit dyspepsia, control apoplexy, middle gas, in Evil, coma due to blocking of the respiratory system, accumulation abdominal mass." " lid musk deer walks to alter, and can lead to the unfavorable of all keys, and the heap soil or fertilizer over and around the roots for opening channels and collaterals is held back, if all wind, all gas, all blood, all Bitterly, all diseases of frightened epilepsy, abdominal mass, channels and collaterals, which are stopped up, to be closed, the unfavorable person of hole key, and pacifying must be without being to guide to lead to what is opened.It is non-unavailable, but Ear can not be crossed ".It can be seen that its drug effect is extensive, but predominantly guiding is used.
Experimental example brief introduction:
Since 2013, on the basis of toxic side effect is not found by toxicological experiment, substantial amounts of clinic trial is carried out, has been taken Obtained the effect of being satisfied with.The experimental conditions of one group of prescription are only exemplified by below:
12-18 parts of copper ash, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid are bad The weight such as propylhomoserin, alanine, arginine, aspartic acid, cystine, leucine, proline, tyrosine, histidine, valine Part, 1-3 parts of sandalwood oil, 1-3 parts of caryophyllus oil, 2-5 parts of dimethoxycoumarin, 0.1-0.8 part of iridin, 16-24 parts of cardamom For 8-12 parts of Amomum cardamomum, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, 1-3 parts of myrobalan's tannic acid, manually 8-12 parts of cow-bezoar, 1-2 parts of muscone.
Wherein, Amomum cardamomum, nutmeg, radix glehniae, HEIYUNXIANG, beat powder and cross more than 60 mesh and sieve, mixed i.e. with other bulk drugs Into.
Instructions of taking:Adult 1.5-2g/ times, takes 2-3 day.One week is a course for the treatment of.
Disease amelioration is effective, and for 3 months no relapse of symptom disappearance follow-up to cure, medication has no that mitigation is nothing for two weeks Effect.Pulmonary lesion species, number of cases and treatment such as following table:
Disease amelioration is effective, and for 3 months no relapse of symptom disappearance follow-up to cure, medication has no that mitigation is invalid for two weeks.Lung Portion's lesion species, number of cases and treatment such as following table:
Efficient=(Significant figure+healing number)/ total number X 100%, cure rate=healing number/total number X 100%.
Experiment proves:This medicine has for pulmonary lesions such as cough ant phlegm, chest pulmonary abscess, tuberculosis, lung cancer preferably to be controlled Therapeutic effect, have dosage small compared with conventional medicine, be easy to take, cost is low, and toxic side effect is low to wait clear superiority.
Second of embodiment:
On the basis of the first embodiment, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of amino acid uses artiodactyl 1-38 parts of angle replacement.Form following prescription:
12-18 parts of copper ash, 1-38 parts of artiodactyl angle, 2-5 parts of hydrous calcium sulfate, 1-3 parts of sandalwood oil, caryophyllus oil 1-3 Part, 2-5 parts of dimethoxycoumarin, 0.1-0.8 part of iridin, 1-3 parts of linaloe oil, 1-3 parts of carthamin, 16-24 parts of cardamom For 8-12 parts of Amomum cardamomum, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, 1-3 parts of myrobalan's tannic acid, manually 8-12 parts of cow-bezoar, 1-2 parts of muscone.
1-38 parts of the artiodactyl angle includes 8-12 parts of PULVIS CORNUS BUBALI CONCEN TRATUS, 1-3 parts of antelope's horn, deer horn 8-12 One of part, 8-12 parts of ox horn, 8-12 parts of pilose antler or two kinds and two or more.
Cornu bubali, English name Buffalo Horn, Latin literary fame Cornu Bubali, double angles of bovid buffalo.Water Ox horn (cholesterolo) containing cholesterine, cardiac stimulant composition, peptides, angle fiber;And serine (serine), glycine (glycine), alanine (alanine), lysine (lysine), histidine (histidine), aspartic acid (aspartic Acid), arginine (arginine), threonine (threonine), glutamic acid (glutamic acid), proline (proline), cystine (cystine), methionine (methionine), isoleucine (isoleucine), leucine (leucine) several amino acids such as, tyrosine (tyrosine), phenylalanine (phenylalanine), it is bitter in taste salty, tremble with fear, nothing Poison.Enter the heart, liver, spleen, stomach four to pass through.The effect of with heat-clearing, cool blood, removing toxic substances.It is usually used in controlling pyreticosis headache, high fever coma, macula, Hematemesis, child convulsion, larynx numbness pharynx swelling.
Antelope's horn is conventional Chinese medicine,《Sheng Nong's herbal classic》It is classified as middle product.The former animal of modern commercially available certified products is sahilite (Saiga tatarica L.-- vertebrate Vertebrata, Mammalia Mammalia, Artiodactyla Artiodactrla, hole Angle section Bovidae).Alias saiga tatarica.Sahilite angle egg containing angle(keratin)Calcium phosphate, insoluble inorganic salts, lysine (lysine), serine(serine), glutamic acid(glutamic acid), phenylalanine(phenylalanine), leucine (leucine), aspartic acid(aspartic acid), tyrosine(tyrosine)Deng 17 kinds of amino acid, and contain five kinds of phospholipids Composition, i.e. lecithin(lecithine), cephalin(cephalin), sphingomyelin(sphingomyelin), phosphatidyl silk Propylhomoserin(phosphatidylserine), phosphatidylinositols(phosphatidylinositol)Deng composition.Phosphoric acid calcium, angle egg Insoluble inorganic salts of bletilla etc., wherein keratin content is most.The keratin sulfur-bearing of antelope's horn only has 1.2%, is contained in keratin One of sulfur content those at least.Its pharmacological action of modern study has:1. the effect of Central nervous system:Antelope's horn crust leaches liquid energy The oriented locomotor reaction of mouse is reduced, Central nervous system has inhibitory action, can accelerate opening for barbital and etherization Beginning speed, significantly reduce to leptazol, strychnine, electroconvulsive shock sensitiveness, but do not cause of flaccid muscles.Antelope's horn is decocted Agent 10g/kg can significantly reduce the convulsions rate caused by caffeine and accelerate its recovery rate, reduce the death rate to mouse gavaging. To mouse peritoneal injection antelope's horn alcohol extract 10g/kg, water decoction 2g/kg, hydrolyzate 80mg/kg, it can extend thiobarbiturate The length of one's sleep of sodium.Mouse peritoneal injection antelope's horn parenteral solution 80mg/kg, it can also extend the length of one's sleep of yellow Jackets.2. Refrigeration function:Antelope's horn decoction causes the rabbit of heating to have a refrigeration function to typhoid, paratyphoid B and triple vaccine, 2 after gavage Hour body temperature is begun to decline, and is gradually recovered after 6 hours.3. antihypertensive effect:With antelope's horn alcohol extract 1g/kg to anesthetized dog or cat Intravenous injection, can reduce blood pressure.Conscious Rat application antelope horn preparation 1g/kg is given, also there is obvious antihypertensive effect.4. other Effect:Antelope's horn enzyme, acid hydrolysis liquid are to staphylococcus aureus, Pseudomonas aeruginosa, Bacillus influenzae, beta streptococcus and influenza virus There is different degrees of inhibitory action.Antelope's horn crust leachate, tolerance of the animal to anoxic can be increased, there is analgesia to make With.
Deer horn, English name " Deerhorn, Antler " latin name sika deer CervusnipponTemminck or red deer C.elaphusL, wild white deer CervusmaoneilliLydekker, white lip C.AlbirostrisPrzewalski, red deer C.unicolorKerr.Chemical analysis:Deer horn contains colloid 25%, calcium phosphate 50%-60%, calcium carbonate and nitride.Separately contain amino Acid, inside there is aspartic acid(aspartic acid), threonine(threonine), serine(serine), glutamic acid (glutamic acid), proline(proline), glycine(glycine), alanine(alanine), valine (valine), leucine(leucine), isoleucine(isoleucine), phenylalanine(phenylalanine), lysine (lysine), histidine(histidine), arginine(arginine).Pharmacological action:Antiinflammatory action;Crinosity deer horn n-butanol Extract(BETA)50mg/kg intraperitoneal injections award rat, it is seen that the monoamine oxidase of rats'liver and brain tissue Mitochondria (MAO)Activity is substantially suppressed.Experiment in vitro also proves to have to MAO inhibitory activity.Cornu Cervi extract 40mg/kg, fluorine can be made Alkane light anesthesia dog cardiac output substantially increases.
Ox horn, mainly ox angle, latin name:Bostaurus domesticus Gmelin, main chemical compositions:Steroid Alcohols;Amino acid:Alanine, arginine, aspartic acid, cystine, leucine, proline, tyrosine, histidine, valine; Peptides:The hydrolysis of alkaline peptides, both produce arginine, lysine, histidine, glycine, alanine, proline, valine, Leucine etc.;Guanidine derivative;Protein.Meridian distribution of property and flavor:It is bitter, salty, tremble with fear.The heart, liver, stomach three pass through.Cure mainly:For blood-heat bleeding Spit blood, bleeding from five sense organs or subcutaneous tissue, ulcerative carbuncle furuncle.
Pilose antler, when the tender angle of stag does not grow up to os osseum, band fine hair, containing blood.It is a kind of valuable Chinese medicine, as nourishing Tonic, it is effective in cure to weakness, neurasthenia etc..Because former animal is different, it is divided into pilose antler of sika(Yellow young pilose antler)And cervus elaphus linnaeus(Blue or green hair It is fine and soft)Two kinds;It is divided into again because collecting method is different and cuts fine and soft and saw fine and soft two kinds;Because branch pitches how many and old tender difference, can be divided into again Saddle, two thick sticks, Gua Jiao, three troubles, to cut young pilose antler, lotus flower etc. a variety of for flower.[nature and flavor] are sweet, salty, temperature.[channel tropism] returns kidney, Liver Channel.[function] Invigorating kidney yang, marrow is mended, strengthening the bones and muscles, adjusts punching to appoint, torr sore poison.[curing mainly] kidney deficiency, dizziness, deafness, mesh are dark, impotence, involuntary emission, Gong Leng Under infertile, thin thin, refreshing tired, chilly, spinal column crymodynia, muscles and bones impotence, uterine bleeding band, cloudy subcutaneous ulcer is not held back and the diseases such as prolonged illness is deficient.
Among above-mentioned animal horn, PULVIS CORNUS BUBALI CONCEN TRATUS category commercially available product, pilose antler can use conventional method to use, and antelope Angle, deer horn, ox horn then need to produce using new processing method.A kind of preferable processing method is described below:Soaked with 75% ethanol After bubble or steam disinfection, fine powder is ground into.Add 10 times of weight waters to decoct twice, 7~10 hours every time, mended at any time in decoction process The moisture boiled off is filled, collecting decoction, filtration, filtrate is concentrated into 1-the 5% of original weight amount, after being dried below 80 DEG C, is ground into thin Powder, sieving, is produced.Mixed with other bulk drugs, the formulations such as ball, scattered, cream or capsule are made.
Bulk drug alternate standard:Efficient and cure rate lower limit range of decrease compared with the first embodiment is less than 2 percentages Point, higher limit are unlimited.Following four combination meets alternate standard.
1. 8-12 parts of PULVIS CORNUS BUBALI CONCEN TRATUS, 1-3 parts of antelope's horn, 8-12 parts of pilose antler.
2. 8-12 parts of PULVIS CORNUS BUBALI CONCEN TRATUS, 1-3 parts of antelope's horn, 8-12 parts of deer horn.
3. 8-12 parts of PULVIS CORNUS BUBALI CONCEN TRATUS, 1-3 parts of antelope's horn, 8-12 parts of deer horn, 8-12 parts of pilose antler.
4. 18-22 parts of horn powder, 1-3 parts of antelope's horn, 8-12 parts of pilose antler.
It is demonstrated experimentally that the 3rd combined effect is best, first combined effect takes second place, but cost is relatively low, resultant effect compared with It is good.The same period curative effect of second combination is less than other two groups, but cost is minimum, still with clinical meaning.4th kind is replaced with ox horn For cornu bubali, equivalent effect slightly subtracts, but medicine source is sufficient, and cost is cheap, can escalated dose, thus there is feasibility.
The third embodiment:
On the basis of second of embodiment, sandalwood oil, 1-3 parts are substituted by 8-12 parts of Santalum album, 8-12 parts of santal.
Santalum album is the Santalaceae evergreen dungarunga santal SantalumalbumL. wooden heartwood of drying.Containing volatile oil, oil Containing α-santalol and β-santalol more than 90%.It is used as medicine, nature and flavor are pungent, temperature.Enter lung, stomach, the spleen channel.Can the wide chest of qi-regulating, dissipate Cold analgesic, can declare stagnant, the smooth wide chest of diaphragm of getting angry, warming stomach for dispelling cold.The diseases such as all chest and abdomen pain, dysphagic vomiting, can apply.Heat can be controlled Disease.It if external application for curing, can go to swell with anti-inflammatory, nurse one's health skin quality.Anti-aging, it is to treat dermopathic main medicine in Ancient Times in China period Material.
Santal contains volatile oil, and its principal component is α and β-santalene (α-, β-santalene), wingceltis terpene (santene), wingceltis Terpene ketone (santenone), α-wingceltis terpene alcohol, (a-santenol), sandatone (santal one), santalic acid (santalic Acid), teresantalic acid (teresantalic acid);Another pigment containing santal (santalin), deoxidation santal pigment (deoxysantalin) etc..It is warm-natured, acrid flavour.Returns spleen, stomach, the heart, lung channel.Promoting the circulation of qi middle benefit gas, appetizing analgesic.For cold obstruction causing qi stagnation, chest Bitterly, suffer from abdominal pain, deficiency of food of having a stomachache, coronary heart disease, angina pectoris.
The Santalum album, santal, which are beaten powder and crossed more than 60 mesh, to be sieved, and is mixed with other bulk drugs, and ball is made, dissipates, cream or glue The formulations such as capsule.
It is demonstrated experimentally that substituting sandalwood oil with Santalum album and santal, in addition to increasing dosage, drug effect influence is atomic, Cost is greatly reduced, and for basic hospital, has certain practical value.
4th kind of embodiment:
On the basis of the third, caryophyllus oil by 8-12 parts of replacements of cloves.
Cloves Syzygium aromaticum (L.) Merr. EtPerry are the bud of plant clove of myrtaceae.Bud It is caryophyllus oil containing volatile oil.Eugenol (Eugenol), acetyleugenol, B- carypohyllenes (B mono- are mainly contained in oil ), and methyl-n-amyl ketone, gaultherolin, Humuleno (Humuleno), benzaldehyde, benzylalcohol, a first Caryophyllene Epoxide benzaldehyde, benzyl acetate, chavicol (Chavicol), ylangenes of a mono- (Ylangene of a mono-) etc..Kidney can be warmed up, drop is inverse.Often For cure hiccup, vomiting, gastric disorder causing nausea, rush down dysentery, trusted subordinate's crymodynia, Xuan addictions, hernia, tinea.《Haiyao Bencao, Oversea Materia Medica》It is loaded with:Main wind infantile malnutrition due to digestive disturbances or intestinalparasites is hidden, Bone groove labor is smelly.Gas is controlled, black moustache hair, desinsection, five hemorrhoid is treated, wards off evil and uncharm.Milk headdress flower is controlled, only multicolored fulminant dysentery, healthy tendency, only pain in the chest and abdomen.
Cloves, which beats powder and crossed more than 60 mesh, sieves, and is mixed with other bulk drugs, and ball is made, dissipates, the formulation such as cream or capsule.
It is demonstrated experimentally that substituting caryophyllus oil with cloves, in addition to increasing dosage, drug effect influence is atomic, and cost significantly drops It is low, for basic hospital, there is certain practical value.
5th kind of embodiment:
On the basis of the 4th kind of embodiment, iridin with 8-12 parts of 8-12 parts of iris or blackberry lily or 8-12 parts of elegant jessamine Or 8-12 parts of replacements of fringed iris.
Iris, scientific name:Iris tectorum Maxim., also known as:Blue butterfly, The purple butterfly, flat bamboo etc., belong to lucid asparagus Mesh, it is the rhizome of irides iris.Containing tectoridin (tectoridin), iris Neogroside A, B (iristectorinA, B), Irone glucoside (tectoruside) etc..Acrid flavour is bitter, trembles with fear, poisonous.Can promoting blood circulation expelling wind and removing dampness removing toxic substances disperse accumulations.It is usually used in bruise Carbuncle furuncle poison traumatism and bleeding is controlled in damage, rheumatalgia pain, abscess of throat, dyspeptic abdominal distention, malaria, pyogenic infections, hemorrhoid complicated by anal fistula, external application.
Blackberry lily, alias:Black fan, Wu Pu, night are done, black Wooden-fan, crow are blown, careless ginger, English name:Blackberrylily Rhizome, for the rhizome of irides blackberry lily, isoflavone-containing constituents:Irigenin(irigenin), tectorigenin (tectorigenin), shekanin(tectoridin), Isoflavones Extracted from Belamcanda Chinensis(belamcanidin), methyl purpleking iris (Iris germanica var nepalensis) Flavones(methylirisolidone), tectorigenin Neogroside member(iristectoriginin)A, foreign irisin (irisflorentin), iridin(iridin), 5- removes first ocean irisin(noririsflorentin)Deng.Be used as medicine nature and flavor Hardship, tremble with fear, it is poisonous, enter lung, Liver Channel.For heat-clearing and detoxifying herb, there is removing toxic substances relieving sore-throat, clearing lung-heat heat and dissolving phlegm saliva, radiating disappear the work of knot With.Cure mainly:Larynx numbness pharyngalgia is controlled, cough with dyspnea, accumulation and obstruction of sputum, scrofula tuberculosis, malaria is female, women's Amenorrhea, carbuncle sore tumefacting virus.Modern study Blackberry lily has resisting pathogenic microbes effect, antiinflammatory action, estrogen-like action, refrigeration function, the formation for suppressing gastric ulcer, cholagogic And anti thrombotic action.
Elegant jessamine (Flos Puerariae) be legume pueraria lobata (Pueraria Lobate (Willd.) ohwi), The flower of sweet kudzu (Pueraria thomsonji Benth.), different name Pueraria lobota bar flower, it be used to alleviate vomiting etc. after drinking for a long time Symptom, its principle active component are isoflavonoids, and therefrom separation identifies more than ten and plants such compound at present, mainly Exist in the form of glycosides, it is common such as contg. glucoside of pueravia flower, tectorigenin -7-O- xylose glucoses glycosides, iridin, genistein, thorn awns handle Florigen etc., these isoflavonoids have antioxidation, bacteriostatic activity, antitumaous effect, can prevent and treat osteoporosis, the heart Popular name for etc..
Fringed iris, for the herb of irides fringed iris, isoflavone-containing class compound:Butterfly florigen A, B, tectorigenin Neogroside A, B, irigenin, purpleking iris (Iris germanica var nepalensis) flavones, 7-O- methyl sweet peas glucoside member, storehouse door irisin methyl ether, Buddhist nun's iris are yellow Plain methyl ether,-O- the acetyl group -6,2 of Chinese juniper glucoside member B, 5,7- bis- ', 3 ', 4 ', 5- pentamethoxyl isoflavones,-O- the acetyl of 5,7- bis- Base -6,2 ', 3 ', 4- tetramethoxy isoflavones.Petal contains embinin, swertisin.Fringed iris is sweet, bitter, puts down, can detoxify, and subsides a swelling Analgesic.Clinic be used for treat hepatitis, hepatomegaly, hepatodynia, laryngalgia, stomach trouble, lumbar sprain, arthralgia, and sore, furuncle, scabies, Tinea, itch etc..
The iris, blackberry lily, elegant jessamine, fringed iris, which beat powder and crossed more than 60 mesh, sieves, and mixes, is made with other bulk drugs The formulations such as ball, scattered, cream or capsule.
Above-mentioned Four Plants medicine contains iridin, and wherein iris, blackberry lily, fringed iris belongs to Iridaceae, all multiple characters and use together Way is close, has similar effect for the PUD D through experiment.And legume pueraria lobata flower (Flos Puerariae) Though not belonging to together, iris methods of glycosides activity contained by its recent research achievement proof is very strong, the experiment proved that also alternative iris Glycosides reaches therapeutic purposes.
6th kind of embodiment:
On the basis of the 5th kind of embodiment, 2-5 parts of calcium sulfate, 8-12 parts of replacements of gypsum.
Gypsum is monoclinic system mineral, and main chemical compositions are calcium sulfate (CaSO4).According to relevant information, calcium sulfate slightly soluble Yu Shui, but take orally and enter stomach, in the presence of hydrochloric acid in gastric juice, a part is transformed into calcium chloride, becomes soluble calcium salt.Inorganization Learn with organic chemistry, have calcium chloride salt only, nitric acid calcium salt is dissolved in water, is dissolved in the material of water with the flowing of blood, defeated to arrive machine Each position of body, participate in the physiological function of body.When calcium ion runs into organism metabolism or pathogenic microorganisms in machine in body Organic acid caused by vivo, will make it become insoluble calcium phosphate, lose toxicity.Particularly high fever patient, metabolic occurs Acid poisoning, it is excellent with its gypsum preparation, even more achievement:It has not only neutralized the organic acid for causing poisoning, and it is micro- with causing a disease Amino acid effect in biology, makes it lose nutrition and be suppressed.Although gypsum is not antibiotic, but he serves antibiotic suppression The effect of pathogenic microorganisms breeding development processed, it is not that antibiotic surpasses antibiotic, and acts on wide spectrum, to all pathogenic microorganisms All effectively, and drug resistance does not occur, has no side effect;Although gypsum is not antipyretic, but it has neutralized toxin and has moved back body Burn, serve the effect of alexipyretic;Calcium ion can not only maintain nerve normal function, and can also with body allergy caused by Histamine acts on, and it is lost activity, and antiallergy.Calcium preparation also has the effects such as stop blooding, prevention body fluid oozes out, diminished inflammation, Treatment burn is of miraculous efficacy.
This has satisfied effect it is demonstrated experimentally that substituting calcium sulfate with gypsum.
7th kind of embodiment:
On the basis of the 6th kind of embodiment, 2-5 parts of the dimethoxycoumarin by 8-12 parts of 8-12 parts of artemisia scoparia or oriental wormwood Substitute.
Artemisia scoparia, the perennial Bi sheets of English name Artemisia scoparia Waldst. et Kit. composite family artemisias or near First, biennial herb.Herb is containing organic acid (citric acid, malic acid, acetic acid, propionic acid, valeric acid), rutin, Quercetin 1 Glucose galactose glucoside, the glucose galactose glucoside of Kaempferol 1, the rutinose galactoside of Quercetin one 3,7 one, Quercetin one The double galactoside of 3,7 one rutinoses, cumarin, isocoumarin, β-sitosterol, pyrogallic tannin, volatile oil (thujanol, just Butyraldehyde, furfural, methyl heptenone, Eucarvone, 1,8 one Cineoles, absinthol, acetic acid Mang ox ester, cadinene, Eugenol, α mono- Firpene, β-firpene, agropyrene etc.), fat oil (myristic acid, palmitic acid, stearic acid, arachidic acid, linoleic acid, oleic acid etc.), 4 Monohydroxy acetophenone, choline, salicylic acid etc., azelaic acid, carypohyllene epoxides etc..Siliceous, lead in herb ash content, sodium, potassium, The elements such as iron, magnesium, phosphorus, barium, strontium, silver, titanium, chromium, copper, aluminium, zinc, nickel, zirconium, gallium.Seed includes yellow wormwood artemisia lactone, scoparone. Leaf and flower are containing capillin, the l- alcohol of 2,4 one hexadiine of 1- phenyl one, the fragrant blue aldehyde of folder.Five kinds of flavones are separated in inflorescence:7 monomethyls Aromadendrin, rhamnocitrin, Eupalitin, Crisimaritin, Eupatolitin and 7 monomethyl aesculetins, Scoparone and scopolactone.Be used as medicine bitter, pungent, cool in nature.Clearing lung-heat, cough-relieving, apocenosis.Control cough with lung heat, dyspnea, lung purulence It is swollen, cold cough, " heat of fighting ", abscess of throat.
Oriental wormwood, English name Capillary Wormwood Herb, alias:Artemisia stelleriana, pine tag Chinese mugwort, Tian Naili, are feverfew Artemisia capillaris Artemisia capillaris Thunb. aerial part.Containing volatile oil, in oil composition have laurene, limonene, It is eucalyptol, australene, amphene, α-curcumene, another up to a watt ketone, capillin, eugenol, isoeugenol, naphthalene, benzaldehyde, borneol Containing capillarisin, 6,7- escoparones, arcapillin A, B.It is bitter in taste, pungent, it is slightly cold.Returns spleen, stomach, liver, gallbladder channel. Can clearing heat and promoting diuresis, removing jaundice.Cure mainly:Jaundice, difficult urination, wet sore itch, infectious jaundice type hepatitis etc..Modern pharmacology research Prove that oriental wormwood plays the role of cholagogic, promotes cholic acid and bilirubin discharge in choleresis, increase bile, heart coronary artery blood can be increased Flow, improve microcirculation, and have antipyretic, anti-inflammatory, lowering blood pressure and blood fat, anticoagulation, diuresis is antipyretic relievings asthma, drives away roundworm and suppression Make the effect of a variety of pathogenic dermatophytes and bacterium.Mutagenesis of the Artemisia capillaris water decoction to AFB1 significantly inhibits effect Fruit, prompting may be significant to preventing liver cancer.Oriental wormwood, which has, promotes leucocyte division, increases number of white blood cells, improves T cell Immunocompetence, the effect such as immunological regulation and inducement interferon of body is participated in, thus improve the immunologic function of body from many aspects. Also anti-Leptospira, roundworm is killed, is relievingd asthma, presses down and kills Mouse Ehrlich Carcinoma Cells, MethA cytosiies.
Artemisia scoparia, oriental wormwood, which beat powder and crossed more than 60 mesh, sieves, and is mixed with other bulk drugs, and ball is made, dissipates, the agent such as cream or capsule Type.
Artemisia scoparia and a variety of characters of Artemisia capillaris and effect are close, thus are considered as two raw materials of anaesthetic oriental wormwood.This experiment It is equivalent to also demonstrate that treatment of both bulk drugs for pulmonary lesion has the function that, controlling for dimethoxycoumarin can be substituted Therapeutic effect.
8th kind of embodiment:
On the basis of the 7th kind of embodiment, myrobalan's tannic acid by 8-12 parts of replacements of myrobalan.
Myrobalan, Chinese medicine name.For combretaceae plant myrobalan Terminalia chebula Retz. or fine hair myrobalan Terminalia chebula Retz.var.tomentella Kurt. dry mature fruit.Containing tannin 23.60%~ 37.36%, its composition is Chebulagic acid(Chebulagic acid), chebulinic acid(Chebulinic acid), terchebin (Terchebin), corilagin(Corilagin), glucogallin(Glucogallin), gallic acid (Ellagic acid), the such as 1,3,6- trigalloylglucoses and 1,2,3,4,6- Penta-O-galloyl-D-glucopyranoses still contain thick grass Acid, dehydroshikimis acid, quininic acid, arabinose, fructose, glucose, sucrose, rhamnose and amino acid also contain Sennoside A (Sennoside A), terchebin(Chebulin), tannase(Tannase), polyphenol oxidase(Polyphenol oxidase), the such as peroxidase and ascorbic acid oxidase there is convergence, antidiarrheal, spasmolysis, antibacterial, antiviral etc. to act on, often For relieving diarrhea with astringents, astringe the lung to stop cough, fall fire relieving sore-throat, to protracted dysentery and diarrhea, prolapse of the anus of having blood in stool, the deficiency syndrome of the lung is breathed with cough, and is coughed long more than, pharyngalgia sound is mute Deng having good result.
The myrobalan, which beats powder and crossed more than 60 mesh, to sieve, and is mixed with other bulk drugs, and ball is made, dissipates, the formulation such as cream or capsule.
Experiment proves:By myrobalan, 8-12 parts substitute 1-3 parts of myrobalan's tannic acid, and therapeutic effect is very close, suitable for basic unit people Member's clinical practice.
9th kind of embodiment:
On the basis of the 8th kind of embodiment, substituted for 8-12 parts with agalloch eaglewood in 1-3 parts of the bulk drug linaloe oil, carthamin 1-3 parts with 8-12 parts of safflower replacement.
Agalloch eaglewood, English name Chinese Eaglewood, alias:Agar, suspension culture of Aquilaria sinensis, tabernaemontanus bulrush are fragrant, are dicotyledon medicine winter daphne Magaphanerophytes of section agalloch eaglewood Aquilaria agallocha (Lour.) Roxb or suspension culture of Aquilaria sinensis A. sinensis (Lour.) Gilg after by the injury of nature or by artificial destruction during self-regeneration, the grease that secrets out of by The infection of fungi, the secretion condensed into.Containing benzylacetone, to methoxybenzyl benzylacetone, hydrogenation osmanthus in the volatile oil of agalloch eaglewood Skin acid, to methoxyl group hydrocinnamic acid, agarospirol(Agaro- spirol), linalool(Agarol), agarofuran (Agarofuran), dihydroagarofuran, 4-Hydroxydihydroagarofuran, 3,4- dihydroxy dihydroagarofurans C16H28O2, Nor-Ketoagarofuran(Nor-ketoaga- rofuran)Deng.Nature and flavor are pungent, bitter, temperature.Returns spleen, stomach, kidney, lung channel, it is usually used in controlling Treat the circulation of vital energy in the wrong direction to pant, vomit hiccup, abdominal distention, waist and knee void is cold, and large intestine void is secret, the leaching of urine gas, man's cold sperm.It is swollen to treat geomantic omen poison, Bad odor is removed, it is swollen to treat evil core poison.
Safflower, Chinese medicine scientific name Flos Carthami.(English) Safflower, it is feverfew safflower Carthamus Tinctorius L. tubular corolla.Also known as safflower, warm-natured, acrid flavour, invigorate blood circulation, blood stasis removing analgesic.For coronary heart disease, fall Beat damage, blood stasis and swelling pain, Amenorrhea, dysmenorrhoea, lochia, abdominal mass lump in the abdomen, sore swell and ache curative and haematemesis and have the stagnant person of the stasis of blood.
Agalloch eaglewood, safflower, which are beaten powder and crossed more than 60 mesh, to be sieved, and is mixed with other bulk drugs, and ball is made, dissipates, the formulation such as cream or capsule.
It is demonstrated experimentally that the substitution effect of this example is good, medicine source is sufficient, suitable for basic medical unit and librarian use.
Tenth kind of embodiment:
On the basis of the first or the 9th kind of embodiment, 8-12 parts of tsaoko, 8-12 parts of adder-wort, the tuber of dwarf lilyturf are added in bulk drug 8-12 parts, 8-12 parts of fragrant plantain lily flower, white lettuce wins 8-12 parts.
Tsaoko, scientific name:Amomum tsaoko, are Zingiber cardamom platymisciums, the fruit of tsaoko, alias SEMEN TSAOKO, tsaoko Son.Fruit contains volatile oil, and the main component in oil is australene (α-pinene), nopinene (β-pinenen), 1, 8-Cineole (1,8-cineole), ρ-poly- cymene (ρ-cymene), linalool (linaloolo), alpha-terpineol (α-terpineol), orange The flower tertiary alcohol (nerolidol), aldehyde C-9 (nonanal), capraldehyde (capric aldehyde), trans-2-and-ecenal (trans-2- Undecenal, it is the piquancy component in this product), neral (neral), Geraniol (geraniol);Another (the μ containing trace element g/g):Zinc 69.2, copper 7.33, iron 57.2, manganese 283.7, cobalt 0.89.Acrid flavour, it is warm-natured, it is nontoxic.Enter the spleen channel, stomach.Function:Eliminating dampness Except cold, eliminating the phlegm preventing malaria, spleen benefiting and stimulating the appetite, inducing diuresis for removing edema.Cure mainly:Malaria, phlegm and retained fluid feeling of fullness, coldness and pain in the epigastrium, gastric disorder causing nausea, vomiting, rush down dysentery, food Product.Use scope:The diseases such as abnormal heat, cough, oedema, difficult urination, hot frightened, the first-born sore swells of children.
Adder-wort, English:Rhizoma Bistortae latin names:Polygonum bistorta L. [P.Lapidosum Kitag. " alias:Salvia chinensis, mountain shrimp, careless river car, polygonaceae plant adder-wort Polygonum bistorta L. rhizome.Containing nutgall Acid(gallic acid), benzoaric acid(ellagic acid)And condensed tannin and condensed tannin.Also catechu containing dextrorotation Phenol(catechol), left-handed table tea phenol(epicatechol), 6-Galloyl Glucose galloylglucose), 3,6- bis- do not have Gallate-based glucose(3,6-digalloyl glucose glucose(glucose).Hydroxyl tectoquinone, vitamin again [2], isomers of cupreol etc..Herb contains chlorogenic acid(chloroenic acid), caffeic acid(caffeicacid), former youngster Boheic acid(protocatechuic acid)And hyperin(Hyperin) etc..It is bitter in taste, it is cool.Return lung, liver, large intestine channel.Can be clear Heat is relieving convulsion, manages wet detumescence.Cure mainly that pyreticosis is frightened to jerk, lockjaw, dysentery characterized by blood in the stool, carbuncle swells, scrofula.Clearing heat and promoting diuresis;Cooling blood and hemostasis;Removing toxic substances dissipates Knot.Main lung heat cough adder-wort is coughed;Pyreticosis frightened epilepsy;Dysentery characterized by blood in the stool;Heat is rushed down;Spit blood;Bleeding from five sense organs or subcutaneous tissue;Hemorrhoid hemorrhage;Carbuncle sore tumefacting virus.
The tuber of dwarf lilyturf, scientific name:In Ophiopogon japonicus (Linn. f.) Ker-Gawl. Liliaceae Ophiopogons Cultigen, perennial evergreen herbaceous plant, there are the thick spire leaf tuber of dwarf lilyturf, the two types tuber of dwarf lilyturf.The also known as tuber of dwarf lilyturf, dwarf lilyturf, Hang Mai Winter, the river tuber of dwarf lilyturf, very little winter, the small tuber of dwarf lilyturf, containing a variety of steroid saponins, ophiopogon saponin A, B, C, D, glucoside member is ruscogenin, Separately contain ophiopogonin B ', C ', D ', glucoside member is diosgenin;Still contain a variety of flavone compounds:Such as tuber of dwarf lilyturf methyl flavane Ketone A, B, ophiopogon flavonoid A, ophiopogonone A, B, Methyl Ophiopogon flavonoid A, B;Separately get 5 homoisoflavone class compounds.Nature and flavor Sweet, slight bitter, is slightly cold.The thoughts of returning home, lung, stomach.There is nourishing Yin and promoting production of body fluid, the effect of moistening lung clears away heart-fire, be used for dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx Numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines.
Fragrant plantain lily flower HostaplantagineaAschers, alias:Beautiful spring rod, white crane be colored, beautiful flower bulb, white jade hairpin, perennial Herbaceous plant, the nature and flavor that are used as medicine are sweet, cool, micro- poison.Can regulating the qi flowing in the channels, promoting blood circulation, qi-restoratives, moistening lung, cough-relieving blood, solution Chinese blister beetle poison, exhausted tire is pregnant, dissipates swollen Poison.Abscess of throat is cured mainly, urinary obstruction, sore, is burnt, is passed out semen, is spitted blood, wind-puff is red to collapse, leukorrhea etc..
White lettuce victory, latin name:Lactuca sativa L. alias:Seed of garden lettuce, Ju Sheng, white lettuce, romaine lettuce, are chrysanthemum The fruit of section plant lettuce.Acrid flavour, hardship, tepor, return stomach, Liver Channel, have diuresis, anti-arrhythmia, promoting lactation, profit small Just, blood circulation promoting competent silt, it is usually used in treating alactation, difficult urination, traumatic injury, pain caused by ecchymoma, scrotum swelling and pain.
The bulk drug added, which can beat powder, to be crossed more than 60 mesh and sieves, and is mixed with other drugs, and ball is made, dissipates, cream, capsule Etc. a variety of formulations.But dose should increase more than 1g on the basis of the first embodiment.
Add above-mentioned raw materials medicine and form a variety of compatibilities, be only exemplified by five kinds of typical experimental examples below:
1. 12-18 parts of bronze medal ash, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, wingceltis 1-3 parts of sesame oil, 1-3 parts of caryophyllus oil, 1-3 parts of linaloe oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, iridin 0.5-1 part, 16-24 parts of cardamom, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, 1-3 parts of myrobalan's tannic acid, calculus bovis factitius 8- 12 parts, 1-2 parts of muscone, 8-12 parts of tsaoko, 8-12 parts of adder-wort, 8-12 parts of the tuber of dwarf lilyturf, 8-12 parts of fragrant plantain lily flower, white lettuce victory 8-12 parts.
Wherein, cardamom, radix glehniae, HEIYUNXIANG, tsaoko, adder-wort, the tuber of dwarf lilyturf, fragrant plantain lily flower, white lettuce victory, which is beaten powder and crossed more than 60 mesh, sieves, Mixed with other bulk drugs.
Instructions of taking:Adult 2-3g/ times, takes 2-3 day.One week is a course for the treatment of.
Disease amelioration is effective, and for 3 months no relapse of symptom disappearance follow-up to cure, medication has no that mitigation is nothing for two weeks Effect.Pulmonary lesion species, number of cases and treatment such as following table:
Disease Number of cases Effectively Cure It is invalid It is efficient(%) Cure rate(%)
Cough ant phlegm 41 7 31 3 92.7 75.6
Chest pulmonary abscess 36 6 26 4 88.9 72.2
Tuberculosis 30 6 19 5 83.3 63.3
Lung cancer 22 14 5 3 86.4 22.7
Efficient=(Significant figure+healing number)/ total number X 100%, cure rate=healing number/total number X 100%.
It can be seen that therapeutic effect is better than the first embodiment.
2. 12-18 parts of bronze medal ash, ox horn 8-12 parts of powder of concentration, 8-12 parts of antelope's horn, 8-12 parts of pilose antler, gypsum 8-12, 8-12 parts of Santalum album, 8-12 parts of santal, 8-12 parts of cloves, 8-12 parts of agalloch eaglewood, 8-12 parts of safflower, 8-12 parts of oriental wormwood, 8-12 parts of blackberry lily, 8-12 parts of Amomum cardamomum, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, myrobalan 8-12 Part, 8-12 parts of calculus bovis factitius, 1-2 parts of muscone, 8-12 parts of tsaoko, 8-12 parts of adder-wort, 8-12 parts of the tuber of dwarf lilyturf, fragrant plantain lily flower 8-12 parts, white lettuce wins 8-12 parts.
Wherein, the processing method of antelope's horn is with after the immersion of 75% ethanol or steam disinfection, is ground into fine powder.Add 10 times of weights Amount decocting is boiled twice, 7~10 hours every time, supplements the moisture boiled off in decoction process at any time, and collecting decoction filters, and filtrate is dense 1-the 5% of original weight amount is reduced to, below 80 DEG C after drying, fine powder is ground into, more than 60 mesh sieves and produce excessively.It is cardamom, radix glehniae, black Yun Xiang, Santalum album, santal, cloves, blackberry lily, oriental wormwood, myrobalan, agalloch eaglewood, safflower, tsaoko, adder-wort, the tuber of dwarf lilyturf, fragrant plantain lily flower, white lettuce victory Beat powder and cross more than 60 mesh and sieve, mixed with other bulk drugs, ball is made, dissipates, the formulation such as cream or capsule.
Instructions of taking:Adult 5-6g/ times, takes 2-3 day.10 are a course for the treatment of.
It is effective to take a course for the treatment of disease amelioration, and 3 months no relapse of symptom disappearance follow-up take medicine two weeks not to cure It is invalid to see mitigation.Pulmonary lesion species, number of cases and treatment such as following table:
Disease Number of cases Effectively Cure It is invalid It is efficient(%) Cure rate(%)
Cough ant phlegm 41 8 28 5 87.8 68.3
Chest pulmonary abscess 32 5 23 4 87.5 71.9
Tuberculosis 32 4 19 9 71.9 59.4
Lung cancer 25 14 5 6 76.0 20.0
Efficient=(Significant figure+healing number)/ total number X 100%, cure rate=healing number/total number X 100%.
It can be seen that therapeutic effect, close to the first embodiment, although dosage is larger, cost is relatively low, still have higher Clinical value.
3. 2-4 parts of verdigris, ox horn 8-12 parts of powder of concentration, 8-12 parts of antelope's horn, 8-12 parts of pilose antler, gypsum 8-12, in vain 8-12 parts of santal, 8-12 parts of santal, 8-12 parts of cloves, 8-12 parts of agalloch eaglewood, 8-12 parts of safflower, 8-12 parts of artemisia scoparia are wild 8-12 parts of flower of kudzuvine, 8-12 parts of Amomum cardamomum, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, myrobalan 8-12 Part, 8-12 parts of calculus bovis factitius, 1-2 parts of muscone, 8-12 parts of tsaoko, 8-12 parts of adder-wort, 8-12 parts of the tuber of dwarf lilyturf, fragrant plantain lily flower 8-12 parts, white lettuce wins 8-12 parts.
Wherein, ox horn, the processing method of antelope's horn are with after the immersion of 75% ethanol or steam disinfection, are ground into fine powder.Add 10 Times weight water decocts twice, 7~10 hours every time, supplements the moisture boiled off in decoction process at any time, collecting decoction, filters, filter Liquid is concentrated into 1-the 5% of original weight amount, below 80 DEG C after drying, is ground into fine powder, more than 60 mesh sieves and produce excessively.Cardamom, north are husky Ginseng, HEIYUNXIANG, Santalum album, santal, cloves, artemisia scoparia, elegant jessamine, myrobalan, agalloch eaglewood, safflower, tsaoko, adder-wort, the tuber of dwarf lilyturf, jade hairpin Colored, white lettuce victory, which is beaten powder and crossed more than 60 mesh, sieves, and mix with other bulk drugs, the formulations such as ball, scattered, cream or capsule are made.
Instructions of taking:Adult 5-6g/ times, takes 2-3 day.10 are a course for the treatment of.
It is effective to take a course for the treatment of disease amelioration, and 3 months no relapse of symptom disappearance follow-up is cure, two treatments of taking medicine Cheng Weijian mitigates to be invalid.Pulmonary lesion species, number of cases and treatment such as following table:
Disease Number of cases Effectively Cure It is invalid It is efficient(%) Cure rate(%)
Cough ant phlegm 43 7 30 6 86.0 69.8
Chest pulmonary abscess 35 5 25 5 85.7 71.4
Tuberculosis 33 4 20 9 72.7 60.6
Lung cancer 27 14 6 7 74.1 22.2
Efficient=(Significant figure+healing number)/ total number X 100%, cure rate=healing number/total number X 100%.
It can be seen that therapeutic effect, close to the first embodiment, although dosage is larger, cost is relatively low, still have higher Clinical value.
4. 2-3 parts of blue stone, 18-22 parts of ox horn, 8-12 parts of antelope's horn, 8-12 parts of pilose antler, gypsum 8-12, Santalum album 8-12 parts, 8-12 parts of santal, 8-12 parts of cloves, 8-12 parts of agalloch eaglewood, 8-12 parts of safflower, 8-12 parts of artemisia scoparia, fringed iris 8-12 parts, 8-12 parts of Amomum cardamomum, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, 8-12 parts of myrobalan, 8-12 parts of calculus bovis factitius, 1-2 parts of muscone, 8-12 parts of tsaoko, 8-12 parts of adder-wort, 8-12 parts of the tuber of dwarf lilyturf, fragrant plantain lily flower 8- 12 parts, white lettuce wins 8-12 parts.
Wherein, ox horn, the processing method of antelope's horn are with after the immersion of 75% ethanol or steam disinfection, are ground into fine powder.Add 10 Times weight water decocts twice, 7~10 hours every time, supplements the moisture boiled off in decoction process at any time, collecting decoction, filters, filter Liquid is concentrated into 1-the 5% of original weight amount, below 80 DEG C after drying, is ground into fine powder, more than 60 mesh sieves and produce excessively.Cardamom, north are husky Ginseng, HEIYUNXIANG, Santalum album, santal, cloves, artemisia scoparia, fringed iris, myrobalan, agalloch eaglewood, safflower, tsaoko, adder-wort, the tuber of dwarf lilyturf, jade hairpin Colored, white lettuce victory, which is beaten powder and crossed more than 60 mesh, sieves, and mix with other bulk drugs, the formulations such as ball, scattered, cream or capsule are made.
Instructions of taking:Adult 5-6g/ times, takes 2-3 day.10 are a course for the treatment of.
It is effective to take a course for the treatment of disease amelioration, and 3 months no relapse of symptom disappearance follow-up is cure, two treatments of taking medicine Cheng Weijian mitigates to be invalid.Pulmonary lesion species, number of cases and treatment such as following table:
Disease Number of cases Effectively Cure It is invalid It is efficient(%) Cure rate(%)
Cough ant phlegm 44 7 31 6 86.4 70.5
Chest pulmonary abscess 37 5 26 6 83.8 70.3
Tuberculosis 36 4 22 10 72.2 61.1
Lung cancer 24 13 5 6 75.0 20.8
Efficient=(Significant figure+healing number)/ total number X 100%, cure rate=healing number/total number X 100%.
It can be seen that therapeutic effect, close to the first embodiment, although dosage is larger, cost is relatively low, still have higher Clinical value.
5. the processing technology of pair above-mentioned prescription is improved, autonomic drug cardamom therein, radix glehniae, HEIYUNXIANG, Asiatic sweet leaf Perfume, santal, cloves, iris, blackberry lily, elegant jessamine, fringed iris, artemisia scoparia, oriental wormwood, myrobalan, agalloch eaglewood, safflower, tsaoko, adder-wort, wheat Winter, fragrant plantain lily flower, white lettuce victory are beaten powder and crossed more than 80 mesh and sieve, after mixing with more than 70% alcohol steep 30-60 minutes, depressurize back Receive ethanol;Extracted 30-60 minutes with ethyl acetate again, crushing is concentrated to dryness after recycling design, crossed more than 60 mesh and sieve, with other Bulk drug mixes, and the formulations such as ball, scattered, cream or capsule are made.
Above-mentioned technique is soaked without being eluted successively with different solvents with general alcohol extract at present by the way of carrying using solvent Mode, which is compared, has three advantages:One the step of being the reduction of solvent extraction;Second, although the composition extracted is in the original location, Still it is easy to patient to absorb;Third, the quality requirement of extraction is not high, the active ingredient of no dissolution still can retain profit With.Instructions of taking:Adult 2-3g/ times, takes 2-3 day.One week is a course for the treatment of.
Using the medicine of above-mentioned technique, effective time is substantially better than previous experiments close to the first embodiment, therapeutic effect Example.The above-mentioned 2nd, 3, the prescription of 4 kind of experimental example this technique is respectively adopted and is processed, average, tie again after testing respectively Fruit is as follows:
Instructions of taking:Adult 3-4g/ times, takes 2-3 times, 7 are a course for the treatment of day.
A week after taking disease amelioration is effective, and to cure, medication has no for two weeks to be subtracted 3 months no relapse of symptom disappearance follow-up Gently to be invalid.Pulmonary lesion species, number of cases and treatment such as following table:
Disease Number of cases Effectively Cure It is invalid It is efficient(%) Cure rate(%)
Cough ant phlegm 43 7 32 4 90.7 74.4
Chest pulmonary abscess 40 6 29 5 87.5 72.5
Tuberculosis 31 6 20 5 83.9 64.5
Lung cancer 24 14 6 4 83.3 25.0
Efficient=(Significant figure+healing number)/ total number X 100%, cure rate=healing number/total number X 100%.
It can be seen that using new processing technology, its taking dose decreases than the 2nd, 3,4 kind of experimental example, takes more square Just, and therapeutic effect has also strengthened.

Claims (10)

  1. A kind of 1. anaesthetic for treating tuberculosis, it is characterised in that:The anaesthetic includes the bulk drug of following parts by weight:Copper spin-off 2-18 parts, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of caryophyllus oil, 1-3 parts of linaloe oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of iridin, myrobalan 1-3 parts of tannic acid, 16-24 parts of cardamom, 8-12 parts of radix glehniae, 8-12 parts of HEIYUNXIANG, 8-12 parts of calculus bovis factitius, muscone 1-2 parts.
  2. 2. the anaesthetic of tuberculosis is treated according to claim 1, it is characterised in that:2-18 parts of the copper spin-off is copper ash (System)12-18 parts or 2-3 parts of 2-4 parts of verdigris or blue stone.
  3. 3. the anaesthetic of tuberculosis is treated according to claim 1, it is characterised in that:2-5 parts of the calcium carbonate, calcium phosphate 2-5 Part, 40-60 parts with artiodactyl angle of 2-5 parts of amino acid substitutes.
  4. 4. the anaesthetic of tuberculosis is treated according to claim 3, it is characterised in that:40-60 parts of the artiodactyl angle includes water One of 8-12 parts of powder of ox horn concentration, 8-12 parts of antelope's horn, 8-12 parts of deer horn, 18-22 parts of ox horn, 8-12 parts of pilose antler or two Plant and two or more.
  5. 5. the anaesthetic of tuberculosis is treated according to claim 1, it is characterised in that:16-24 parts of the cardamom be Amomum cardamomum 8- 12 parts and 8-12 parts of nutmeg.
  6. 6. the anaesthetic of tuberculosis is treated according to claim 1, it is characterised in that:The bulk drug sandalwood oil, caryophyllus oil, agalloch eaglewood Oil, carthamin, dimethoxycoumarin, iridin, myrobalan's tannic acid are substituted by following bulk drug respectively:The sandalwood oil is by Santalum album 8-12 parts of 8-12 parts, santal replacements;The caryophyllus oil is by 8-12 parts of replacements of cloves;The iridin is by 8-12 parts of iris Or 8-12 parts of replacements of 8-12 parts of blackberry lily or 8-12 parts of elegant jessamine or fringed iris;The calcium sulfate 8-12 parts of replacements of gypsum; The dimethoxycoumarin 8-12 parts of replacements of 8-12 parts of artemisia scoparia or oriental wormwood;Myrobalan's tannic acid is by 8-12 parts of replacements of myrobalan; The linaloe oil 8-12 parts of replacements of agalloch eaglewood;The carthamin 8-12 parts of replacements of safflower.
  7. 7. the anaesthetic of tuberculosis is treated according to claim 1, it is characterised in that:The bulk drug adds 8-12 parts of tsaoko, fist 8-12 parts of ginseng, 8-12 parts of the tuber of dwarf lilyturf, 8-12 parts of fragrant plantain lily flower, white lettuce win 8-12 parts.
  8. 8. the manufacturing process of the anaesthetic for the treatment of tuberculosis as claimed in claim 1, it is characterised in that:The antelope's horn, deer horn, ox horn Processing method be with 75% ethanol immersion or steam disinfection after, be ground into fine powder;10 times of weight waters are added to decoct twice, every time 7~ 10 hours, the moisture boiled off to be supplemented in decoction process at any time, collecting decoction, is filtered, filtrate is concentrated into 1-the 5% of original weight amount, After less than 80 DEG C dryings, fine powder is ground into, sieves, produces;Mixed with other bulk drugs, the agent such as ball, scattered, cream or capsule are made Type.
  9. 9. the manufacturing process of the anaesthetic of tuberculosis is treated as claimed in claims 6 or 7, it is characterised in that:The cardamom, radix glehniae, HEIYUNXIANG, Santalum album, santal, cloves, iris, blackberry lily, elegant jessamine, fringed iris, artemisia scoparia, oriental wormwood, myrobalan, agalloch eaglewood, safflower, grass Fruit, adder-wort, the tuber of dwarf lilyturf, fragrant plantain lily flower, white lettuce victory are beaten powder and crossed more than 60 mesh and sieve, and mixs with other bulk drugs, be made ball, scattered, cream or The formulations such as capsule.
  10. 10. the manufacturing process of the anaesthetic of tuberculosis is treated as claimed in claims 6 or 7, it is characterised in that:The cardamom, radix glehniae, HEIYUNXIANG, Santalum album, santal, cloves, iris, blackberry lily, elegant jessamine, fringed iris, artemisia scoparia, oriental wormwood, myrobalan, agalloch eaglewood, safflower, grass Fruit, adder-wort, the tuber of dwarf lilyturf, fragrant plantain lily flower, white lettuce victory are beaten powder and crossed more than 80 mesh and sieve, after mixing with more than 70% alcohol steep 30-60 Minute, ethanol is recovered under reduced pressure;Extracted 30-60 minutes with ethyl acetate again, be concentrated to dryness crushings after recycling design, 60 mesh of mistake with Upper sieve, mixed with other bulk drugs, the formulations such as ball, scattered, cream or capsule are made.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117534544A (en) * 2024-01-09 2024-02-09 四川尊楠生物科技发展有限公司 Method for separating and obtaining high-purity agalloch eaglewood spiro-alcohol

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005107734A1 (en) * 2004-05-06 2005-11-17 Taiyokagaku Co., Ltd. Alcohol metabolism accelerating composition, and food or drink containing the composition
CN107582899A (en) * 2017-10-21 2018-01-16 内蒙古民族大学附属医院 The anaesthetic and its manufacturing process of a kind of clearing away heat to stop bleeding

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005107734A1 (en) * 2004-05-06 2005-11-17 Taiyokagaku Co., Ltd. Alcohol metabolism accelerating composition, and food or drink containing the composition
CN107582899A (en) * 2017-10-21 2018-01-16 内蒙古民族大学附属医院 The anaesthetic and its manufacturing process of a kind of clearing away heat to stop bleeding

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
康爱多网上药店: ""三十五味沉香丸分别有什么成分"", 《HTTPS://WWW.360KAD.COM/MEDICATION/2532048.SHTML》 *
楚伦***: "四味沙参汤治疗小儿迁延性肺炎体会", 《中国民族医药杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117534544A (en) * 2024-01-09 2024-02-09 四川尊楠生物科技发展有限公司 Method for separating and obtaining high-purity agalloch eaglewood spiro-alcohol
CN117534544B (en) * 2024-01-09 2024-03-15 四川尊楠生物科技发展有限公司 Method for separating agalloch eaglewood screw alcohol

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