CN106421424A - Anticancer traditional Chinese medicine electuary and preparation method thereof - Google Patents
Anticancer traditional Chinese medicine electuary and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an anticancer traditional Chinese medicine electuary. The anticancer traditional Chinese medicine electuary is characterized by being prepared from, by weight, 10-15 parts of suberect spatholobus stem, 10-13 parts of red-rooted salvia root, 10-13 parts of glossy privet fruit, 10-15 parts of Mongolian milkvetch root, 10-15 parts of honeysuckle, 10-15 parts of Herba Patriniae, 10-15 parts of kudzuvine root, 6-10 parts of Cortex Phellodendri, 5-8 parts of noble dendrobium stem, 8-12 parts of Radix Angelicae Sinensis, 6-10 parts of Radix Scutellariae, 10-15 parts of kelp, 10-15 parts of Herba Taraxaci and 10-15 parts of fortune eupatorium herb. Prepared from pure traditional Chinese medicines, the anticancer traditional Chinese medicine electuary has the advantages of no additives, no toxic or side effect, excellent anticancer effect, internal heat relieving, detoxifying, collateral dredging, immunity enhancing, heart protecting, kidney strengthening, liver smoothing, spleen tonifying, lung moistening and stomach warming.
Description
Technical field
The present invention relates to a kind of Chinese herbal medicine for preventing electuary and preparation method thereof, the Chinese herbal medicine for preventing of more particularly, to a kind of dredging collateral that relieves internal heat
And preparation method thereof, belong to technical field of traditional Chinese medicines.
Background technology
Channels and collaterals are the big passages of QI-blood circulation in human body, connect whole body acupuncture point and the heart of human body, liver, spleen, lung, kidney, the gate of vitality,
Three Jiao, stomach, courage, large intestine, small intestine, bladder 12 internal organs communicate, and are invisible impalpable institutional frameworks in human body.Channels and collaterals pathology
(I.e. channels and collaterals chronic carbuncle resistance disease)That modern medical equipment checks a kind of not latent disease out, this disease to health so that
Life very harmful.Which position is sick, illustrates that the channels and collaterals leading to that position occur in that chronic carbuncle resistance shape pathology(Or internal organs
Channels and collaterals carbuncle hinders)The metabolic function of the lighter's morbidity internal organs declines, and severe one can be dead to people.
The morbidity of channels and collaterals pathology is concealed, and slow stadium is longer to be had from several years to decades, and the later stage is easily induced into incurable disease
Dead to people.Channels and collaterals pathology originates from hot, wet, cold, evil, the wind five poisonous creatures: scorpion, viper, centipede, house lizard, toad, disease is sent out in tiring out, endure, gas, fire, frightened five because.The appearance of human body
Acupuncture point connection twelve channels and collaterals, twelve channels and collaterals connect 12 internal organs, the five poisonous creatures: scorpion, viper, centipede, house lizard, toad by acupuncture point enter channels and collaterals, entrance internal organs and be deposited on through
So that internal organs metabolic function declines within network and internal organs, incoming call and a variety of toxin eaten are deposited in vivo everywhere, and time is long
Various major diseases will be induced, such as die suddenly, sleep, cancer, cerebral infarction, hemiplegia, cerebral hemorrhage are all that channels and collaterals pathology stadium is excessively elongated
The consequence becoming.
Channels and collaterals pathology is not incurable disease, can prevent and cure, and all there is the reaction of discomfort at the initial stage of channels and collaterals pathology
Tire out as the weak, heart, too fast, the uncomfortable in chest shortness of breath of heart rate, on pull out gas, big forearm is ached and is thought that the doubtful heart disease of this class can not check heart again
The lung the heart channel of Hang-Shaoyin network carbuncle that obtained per capita of disease hinders disease.The people's early stage obtaining this disease can delay disease as reasonably made arrangements for the daily life and moving
The development of feelings, but can not tired it is impossible to exciting, can not vigorous exercise, once overstrain, excessively exciting, angry easily causing
Sudden lung the heart channel of Hang-Shaoyin network resistance is dead, and sudden death is exactly that the burst resistance of lung the heart channel of Hang-Shaoyin network extremely causes dead.Up to high ranking official dazzle expensive, national talent,
Artist, down to ordinary people, have in each year millions of people die from this disease.
Hot, wet, cold, evil, the wind five poisonous creatures: scorpion, viper, centipede, house lizard, toad are the causes of disease of induction channels and collaterals chronic carbuncle resistance, and a pin, two moxibustions, three medications are in 5,000 years
The three big therapies that doctor creates, open resistance except confering, the law having become the traditional Chinese medical science to cure the disease promoting blood circulation and removing blood stasis.Smooth people is anosis for gas promoting circulation of blood, vapour lock blood stasis
All kinds of diseases and ailments are given birth to, promoting the circulation of qi, smooth blood be get rid of illness basic.
Content of the invention
It is an advantage of the invention that it provides a kind of no added, have no toxic side effect, the electuary made with pure Chinese medicine, this Chinese medicine rushes
Agent has good anticancer, relieves internal heat, dredging collateral, improves immunity, shield heart, strong kidney, easypro liver, invigorating the spleen, moistening lung, warm stomach effect.
The technical solution used in the present invention is as follows:
A kind of Chinese herbal medicine for preventing, is made up of the raw medicinal material of following parts by weight:Reticulate millettia 10-15 part, red sage root 10-13 part, glossy privet
Sub- 10-13 part, Radix Astragali 10-15 part, honeysuckle 10-15 part, field pennycress 10-15 part, root of kudzu vine 10-15 part, golden cypress 6-10 part, the stem of noble dendrobium
5-8 part, Radix Angelicae Sinensis 8-12 part, root of large-flowered skullcap 6-10 part, kelp 10-15 part, dandelion 10-15 part, eupatorium 10-15 part.
Preferably, the parts by weight of described each raw medicinal material are:13 parts of reticulate millettia, 12 parts of the red sage root, 12 parts of the fruit of glossy privet, the Radix Astragali 13
Part, 13 parts of honeysuckle, 13 parts of field pennycress, 13 parts of the root of kudzu vine, 8 parts of golden cypress, 7 parts of the stem of noble dendrobium, 10 parts of Radix Angelicae Sinensis, 8 parts of the root of large-flowered skullcap, 13 parts of kelp,
13 parts of dandelion, 13 parts of eupatorium.
Preferably, electuary made by described raw material.
Preferably, take the mixture of described raw medicinal material in proportion, cleaning, 1-3 minute of scalding in 80-100 degree hot water, get rid of
Dry, airing, pulverize through portable pulverizer, cross 140 mesh sieves, mix, steam 30-40 minute, dry, packaging, every bag of 2g.
Being described as follows of each raw medicinal material in formula:
(1)Reticulate millettia【Another name:Blood phoenix rattan, three leaf reticulate millettias, pig blood rattan.】Nature and flavor acrid, sweet, warm.Return liver warp.
A. main component is flavonoids thorn handle florigen, onocerin, ononin, prunetin, Daidezin etc..
B. it is mainly used in treating the deficiency of blood or has the stagnant amenorrhoea of the stasis of blood, delayed menstrual cycle, dysmenorrhoea concurrently, and the deficiency of blood is dizzy, limbs fiber crops
The diseases such as wood, soreness of waist and knee joint, arthralgia due to wind-dampness.
C. reticulate millettia can be enriched blood, to old man, the fire of deficiency type, bematoasthenic myospasm and blockage of main and collateral channels person preferably uses.Modern this product is treated again
The diseases such as raw aplastic anemia, decrease of platelet, leukopenia, the proliferation of mammary gland.
D. reticulate millettia has the external effect suppressing JTC-26 cancer cell.Millettia extract has stronger anti-herpes simplex
The effect of virus.
(2)The red sage root【Another name:Red ginseng, radix salviae miltiorrhizae, red with.】Bitter, cold nature.The thoughts of returning home, Liver Channel.
A. fat-soluble Diterpenoids from bulbus and water-soluble phenolic acrylic component are mainly contained, also flavonoids, triterpenes, sterol etc.
Other compositions.
B. the red sage root is used for Blood stasis, pain, confused and worried disease, warm disease, sore carbuncle swells and skin disease.
C. the red sage root has antitumor action.Red sage root decoction can extend the time-to-live of Ehrlich ascites tumor mouse.The red sage root is to little
Mouse EC, euphorbia egg decoctum have GVT, and can increase endoxan, the anti-EC of camptothecine, liver
The active anticancer of cancer, euphorbia egg decoctum and leukaemia L615.Przewaquinone A is to Mice Bearing Lewis Lung Cancer, melanin tumour b16 and sarcoma
S180 has inhibitory action.Danshen injections is obviously promoted work to Mice Bearing Lewis Lung Cancer and Walkcr256 cancer cell hematogenous spread
With.Tanshinone IIA can promote human lung carcinoma cell line(SPC-A-1)Apoptotic effect, also to human cervical carcinoma cell lines
(mE180), rat liver cancer H22 knurl strain, human leukemia cell line(HL-60), mouse quasi-lymphocyte leukemia P388 knurl strain has
Good induction of differentiation.Tanshinone can induce the effect that the human liver cancer cell (SMMC-7721) of in vitro culture reverses.
D. the red sage root and its formulations toxic are less, but also have the report of bad reaction during clinical practice.By the red sage root and its preparation
The bad reaction causing mainly has allergic drug eruption, allergic asthma, headache, dizziness, palpitaition, shortness of breath, dry, abdominal distension, menstruation
Excessively, bleeding gums etc..
(3)The fruit of glossy privet【Another name:Glossy privet reality, purpleflower holly fruit, quick-fried lattice flea, Chinese wax tree, mouse Chinese catalpa.】Nature and flavor sweet, bitter, cold.Return
Liver and kidney channel.
A. main component is triterpene compound:Oleanolic acid, acetyloleanolic acid, ursolic acid, acetyl ursolic acid, Qi Dun
Tartaric acid sodium salt, hydroxyoleanolic acid, methyl ursolate and tormentic acid etc..
B. it is used for the disease such as the deficiency of liver-yin and kidney-yin, yin asthenia generating intrinsic heat, hypopsia.Additionally, fruit of glossy privet clinic is additionally operable to treat Chronic Benzene
Poisoning, clonic icterohepatitis, glaucoma, hyperlipidemia, infertility, Leukocytes after Chemotherapy minimizing, arrhythmia cordis, senile just
The auxiliary treatment of secret and tumor patient.
C. the fruit of glossy privet plays the role of liver protection, hypoglycemic, anti-inflammatory.
(4)The Radix Astragali【Another name:Astragalus, the continuous Radix Astragali, RADIX ASTRAGALI, the moxibustion Radix Astragali.】Nature and flavor are sweet, temperature.Return lung, the spleen channel.
A. the root of the Astragalus membranacus mainly composition containing saponin(e, flavones, polysaccharide, amino acid etc..
B. Radix Astragali invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.For insufficiency of the spleen all diseases, all diseases of the deficiency syndrome of the lung, sore swollen toxin,
Difficult urination, the disease such as quench one's thirst.Additionally, clinic is additionally operable to prevent and treat the infection of the upper respiratory tract at present, treatment pulmonary heart disease, atrophic gastritis,
Systemic loupus erythematosus, prostate hyperplasia, rotaviral enteritis, vital myocarditis, hepatitis, tumour etc..
C. the Radix Astragali has antitumor action.Radix Astragali water body thing has substantially works in coordination with cell factor promotion cancer of the esophagus TIL propagation and spy
The effect of different in nature killing activity.Astragalus decoction can promote the lymphocyte transformation rate of normal person and tumor patient.
(5)Honeysuckle【Another name:FLOSLONICERAE, honeysuckle flower, honeysuckle, two flowers, two precious flowers.】Nature and flavor are sweet, tremble with fear.Return lung, the heart, stomach.
A. volatile oil, flavonoids, organic acid, triterpenes etc. are mainly contained in honeysuckle.
B. honeysuckle is clearing heat and detoxicating, wind-heat dissipating.For carbuncle swells furunculosis, affection of exogenous wind-heat, warm disease from the beginning of, respiratory tract infection,
Diarrhoea, dysentery.Additionally, this product is additionally operable to hyperlipidemia, tumor radiotherapy, chemotherapy xerostomia etc..And the prevention for " SARS "
And treatment, in the tcm prescription of State Administration of Traditional Chinese Medicine's recommendation prevention " SARS ", in the square medicine having more than half, there is gold and silver
Flower, shows the very important effect in " SARS " preventing and treating of this product.
C. the water of in-vitro screening laboratory report honeysuckle and steeping in wine liquid euphorbia egg decoctum and EC are had significantly thin
Cytotoxicity.Honegsukle flower P.E is administered orally slight preventive effect to Experimental Gastric Ulcer in Rats.N of high dose oral chlorogenic acid energy
Increase gastrointestinal peristalsis, promote gastric juice and choleresis.Additionally, chlorogenic acid can also slightly strengthen adrenaline and norepinephrine
Boosting to cat and rat, but the nictitating membrane response of cat is no affected.
(6)Field pennycress【Another name:Imperial bud Patrinia scaniosaefolia, bitter vegetarian, Patrinia scaniosaefolia, Radix Patriniae.】Nature and flavor are pungent, bitter, are slightly cold.Return stomach, large intestine, liver
Warp.
A. the A of glycosides containing patrinia scabiosaefolia Fiscs, B, C, D, E, F, G in the root of patrinia scabiosaefolia Fiscs and rhizome, its aglycon is oleanolic acid or often
Spring rattan aglycon, the composition of sugar has wood sugar, sandlwood Tang, glucose and arabinose;Contain sitosterol-D-Glucose glycosides, rape steroid again
Alcohol-D-Glucose glycosides and the Patrinia scaniosaefolia glycosides of iridoids;Volatile oil is mainly the Multiple components such as patrinene and isopatrinene.
B. patrinia scabiosaefolia Fiscs has clearing heat and detoxicating, removing blood stasis and expelling pus effect.It is mainly used to acute appendicitis, lung carbuncle hyperpyrexia, pyohemoptysis, stasis
Chest and abdomen pain.Additionally, clinic is additionally operable to treat mumps, acute icteric catarrhal jaundice, acute appendix at present
Scorching, snail fever occurs together ascites, acute tonsillitis, infantile diarrhea, intestinal cancer, carcinoma of urinary bladder, breast cancer, laryngocarcinoma etc..
C. field pennycress has antitumaous effect.The inhibiting rate 50%-70% cancer cell to JTC26 cancer cell for the field pennycress hot water medicinal extract;
The hot water medicinal extract of Radix Patriniae is 98.2% to the inhibiting rate of JTC26, the growth of energy 100% promotion normal cell.Patrinia heterophylla with rough
Leaf Patrinia scaniosaefolia water extract, to mouse peritoneal injection, has direct killing effect to ascitic type S180 oncocyte.
(7)The root of kudzu vine【Another name:Pachyrhizua angulatus, Gan Ge, yellow jin, Pueraria lobota bar, dry Pueraria lobota.】Nature and flavor are sweet, pungent, cool.Returns spleen, stomach.
A. the root of kudzu vine contains isoflavonoid:Puerarin, daidzin, Daidzein, Daidzein -4 ', 7- bis- grape
Glucosides, 7- wood sugar Puerarin, 3 '-hydroxyl Puerarin, 3 '-methoxyl group root of kudzu vine base, onocerin and Genistein, rest-harrow
Element -7- glucoside etc..Additionally, also containing triterpenes components, Coumarins composition etc. in the root of kudzu vine.
B. the root of kudzu vine has expelling pathogenic factors from muscles and skin to bring down a fever, and promotes the production of body fluid, promoting eruption, the function of Shengyang Zhixie.It is mainly used to treat diseases caused by external factors table disease, measles is not
Thoroughly, pyreticosis is thirsty, the deficiency of Yin is quenched one's thirst, and heat expels the heat-evil dysentery, splenasthenic diarrhea.Additionally, the root of kudzu vine is clinically additionally operable to treat coronary heart disease, heart strand
Bitterly, high blood pressure etc..
C. the root of kudzu vine has antitumaous effect.The S86019 extracting from the root of kudzu vine can suppress HL-60 cell proliferation, makes cell by original
Early children grain phasic development be the band form nucleus of middle children's grain, evening children's grain and maturation, the segmented cell becoming ripe.Daidzein energy
Substantially change the formation of B16 cell, inducing mouse melanoma B14 changes.Kudzu root extract can activate animal abdominal cavity huge bite thin
The phagocytic function of born of the same parents, can start picibanik(OK432)Or lipopolysaccharides (LPs) produces TNF in serum
(TNF), have certain inhibitory action to Esc knurl, S180 sarcoma and Lewls lung cancer.Kudzu root extract and endoxan or
Picibanik shares, and the suppression to tumour growth has summation action.The total saposins of the root of kudzu vine show very strong CDCC.
(8)Golden cypress【Another name:Bark of a cork tree wood, bark of a cork tree skin, cork tree.】Nature and flavor are bitter, tremble with fear.Return kidney, bladder warp.
A. little alkali, jateorrhizine, magnoflorine, the Multiple components such as phellodendrine are mainly contained.
B. effect is heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.Golden cypress is used under humid tropics, heat gonorrhea tinea pedis, rush down dysentery are yellow
Subcutaneous ulcer, sore swell and ache curative, eczema wet sore, fever due to yin deficiency, night sweat seminal emission.
C. golden cypress has Photosensitive Anticancer.With BGC-823 gastric carcinoma cells as test material, research golden cypress in 480nm and
Photosensitization to cancer cell under 650nm illumination.Result:Golden cypress dosing irradiation group is to growth of cancer cells, cancer cell tetrazolium bromide generation
Vigor of thanking all has photosensitive depression effect.Golden cypress experimental group cancer cell acid phosphatase content significantly reduces, and cancer cell 3HTdR mixes
Amount significantly reduces;Chromosome is had no with photosensitive cause adhesion distortion effect, but S phase cell cycle process can be delayed.10ml/L and
100ml/L makes the extensive swelling of experimental group cell mitochondrial, endoplasmic reticulum, expansion, and cytoribosome significantly reduces.Prompting golden cypress pair
BGC-823 gastric carcinoma cells have photosensitive depression effect really.
(9)The stem of noble dendrobium【Another name:The fresh stem of noble dendrobium, yellow grass.】Nature and flavor are sweet, light, are slightly cold.Return lung, stomach, kidney channel.
A. main component is HERBA DENDROBII, stem 0.41%-0.64% containing alkaloid;Predominantly dendrobine, the stem of noble dendrobium time alkali, 6- hydroxyl
Base dendrobine, stem of noble dendrobium ether alkali, 6- hydroxyl stem of noble dendrobium ether alkali, 4- hydroxyl stem of noble dendrobium ether alkali, stem of noble dendrobium ester alkali and methine dendrobine etc. are multiple
Material.
B. the stem of noble dendrobium has nourishing Yin and clearing heat, nourishing the stomach to improve the production of body fluid effect.It is mainly used in deficiency of stomach-Yin, Yin and fluid deficiency disease.Kidney deficiency and liver,
Deficiency of YIN-blood disease.Additionally, clinic is additionally operable to treat atrophic gastritis, diabetes and its complication at present, and delay to decline
Always.
C. the stem of noble dendrobium has antitumor action.Stem of noble dendrobium ethanol extract is to A549(Human Lung Cancer cell)、SK-OV-3(Human body ovum
Nest adenocarcinoma cell)And HL-60(Human body progranulocyte leukemia)Deng cell line, there is significant cytotoxic effect;Methyl alcohol carries
Take 4,7- dihydroxy -2- methoxyl group -9 in thing, 10- dihydro phenanthrene has antitumor activity.The stem of noble dendrobium has suppression rat kidney particulate
The effect of body Na+, K+-ATP enzyme, reverse transcriptase and archaeal dna polymerase etc.;Dendrobium Chrysotoxum Lindl all has containing EN, hair orchid phenanthrene, chrysotoxene
Antitumor activity in various degree, EN is the strongest to the inhibitory action of rat liver cancer, the suppression to mouse EC for the chrysotoxene
Making is used the strongest;May there is certain immunosuppressive action simultaneously.
(10)Radix Angelicae Sinensis【Another name:Dry return, the Qin is returned, cloud is returned, west is returned.】Sweet, pungent, warm in nature.Return liver, the heart, the spleen channel.
A. Radix Angelicae Sinensis master composition containing waving property, its volatile oil is made up of neutral oil, phenol oil, acid-soluble oil.Wherein, neutral oil by
The Multiple components such as nopinene, β-phellandrene, laurene form.
B. Chinese angelica blood supplementing promoting blood circulation, menstruction regulating and pain relieving, relax bowel.Clinically it is additionally operable to treat cerebral arteriovenous malformation, in ischemic
Wind, UGB, habitual constipation, dysmenorrhoea, scapulohumeral periarthritis, Temporomandibular Joint Dysfunction, sudden deafness, bronchus are roared
Breathe heavily, hyperlipidemia, high blood pressure, diabetes, pruitus, nettle rash etc..
C. Radix Angelicae Sinensis has antitumor action.Have one to the knurl strain such as mice transplanted tumor EC, Hep, S180, Lewis, B16
Determine the inhibitory action of degree, up to 39%, side effect is less for its inhibition rate of tumor growth, and can long-term prescription.
(11)The root of large-flowered skullcap【Another name:Bar a kind of reed mentioned in ancient books, sub- a kind of reed mentioned in ancient books, withered a kind of reed mentioned in ancient books, rotten intestines.】Nature and flavor are bitter, tremble with fear.Return lung, courage, spleen, large intestine, small intestinl channel.
A. main component has scutelloside, baicalein, wogonin, wogonoside, chrysin, oroxylin, mica
Plain A, the Multiple components such as neobaicalein I and II.
B. root of large-flowered skullcap effect is heat-clearing and damp-drying drug, purging intense heat and detonicating, and hemostasis is antiabortive.The root of large-flowered skullcap is used for damp and hot caused various disease conditions, fire
Various disease conditions caused by heat, blood-head tells nosebleed, fetal movement with fever.Additionally, the root of large-flowered skullcap is clinically additionally operable to treat infantile respiratory tract infection, hook
Leptospiral disease, meningococal meningitis carrier, catarrhal jaundice, acute biliary infection, ephritis, pyelonephritis, high blood
Pressure disease, sty, burning hot nosebleed epistaxis etc..
C. the root of large-flowered skullcap has antitumor action.The research of root of large-flowered skullcap antitumor action is related to different tumor models, relevant report
From immunity, enzymatic activity, to suppression of oncocyte etc. in terms of inquire into the effect link of active ingredient the root of large-flowered skullcap.Scutelloside, baicalein
There is certain inhibitory action with wogonin to the propagation of cancer cell.The Inhibit proliferaton effect of baicalein is that it can be direct
Suppression is expressed to growing related signal factor and protein tyrosine kinase, the mRNA of minimizing growth factor.In experiment made on the living,
E3H/HeN mouse every oral scutelloside 10mg daily, can significantly inhibit tumour and increase, the Scullcap total-flavonoid of various dose
The internal propagation of suppression transplanted sarcoma S180 knurl strain, and be in dose-effect relationship, show the antitumor activity of high-efficiency low-toxicity.The root of large-flowered skullcap is yellow
Ketone A also can suppress the propagation of HCC BEL-7402, when with cis-platinum(Cis), Doxorubicin(Dox), 5 FU 5 fluorouracil(5-
FU)There is addition when sharing or act synergistically, and there is induction of differentiation, it is possible to decrease the expression of telomerase activation.Root of large-flowered skullcap ether carries
Thing has CDCC to mouse leukemia L1210 cell, and ED50 is 10.4mg/ml, and skullcapflavone II is to mouse L1210 cell
ED50 be 1.5 μ g/ml.
(12)Kelp【Another name:River Chinese cabbage, edible seaweed, goose slaps dish.】Nature and flavor are salty, tremble with fear.Return liver, stomach, kidney channel.
A. kelp contains alginic acid, phycocolloid acid, tangic acid, mannitol, laminine, laminine, glutamic acid, asparagus fern ammonia
Acid, proline etc., the polysaccharide such as galactan, vitamin B1, B2, C, P and carrotene, the inorganic salts such as I, K, Ca.
B. kelp can softening and resolving hard mass, dissolving phlegm Li Shui.It is mainly used to the diseases such as goiter and tumor, goitre carbuncle, oedema beriberi edema.Additionally, kelp
The subthyroidism being clinically usually used in correcting iodine deficiency and causing, also can temporarily suppress hyperthyroid newly old
Metabolic rate and mitigation symptoms;And the treatment proliferation of mammary gland, endometriosis, fibroid, atrophic gastritis etc. and preventing and treating
Cataract of old people etc..
C. kelp has antitumor action.Sea-tangle hot water extract has substantially to mouse peritoneal, subcutaneous transplantation tumor S180
Inhibitory action, the material that 40%-80% ethanol precipitation is crossed has the leukemic activity of anti-congenital L1210.The active portion of sea-tangle
Divide and there is good antitumor activity in vivo, there is no activity in vitro;Thallus Laminariae (Thallus Eckloniae) extract is for external human body KB cell(Cancer
Cell)Culture has obvious CDCC, can kill more than 50% cancer cell.Laminaran(Laminaran)And laminaran
Sulfuric ester has facilitation to body's immunity.The laminarin of 5 kinds of different sources is non-toxic, and K562 cell unrestraint is killed
Wound acts on, and the impact to immunologic function is inconspicuous, and anti-cancer effect in vitro is inconspicuous, the laminarin effect phase of 5 kinds of different sources
Seemingly.
(13)Dandelion【Another name:Sow with a drill weeding hoe, Herba Taraxaci, dandelion.】Nature and flavor are sweet, put down, nontoxic.
Dandelion has Detoxicating food-poisoning, scattered stagnant gas, changes heat toxin, and the evil that disappears is swollen, black beard and hair, the function of strengthening the bone.
(14)Eupatorium【Another name:Fragrant thoroughwort, water perfume, a thousand pieces of gold grass, Canton love-pea vine, female orchid, backshank phoenix.】Nature and flavor are pungent, put down.Returns spleen, stomach,
Lung channel.
A. herb 1.5%-2.0% containing volatile oil, its main component has to P-cymene, neryl acetate, Thymol
Methyl ether, and the non-alkali in alkaloid Lip river containing Ningde, the Multiple components such as heliotrine of lying on the back.
B. eupatorium has and removes dampness by means of aromatics, appetizing of being amusing, delivers effect of relieving summer-heat.Eupatorium is used for burnt disease, outer affection by summer-heat in humidity hysteresis
Wet or Wen Wen from the beginning of.Additionally, this product clinic is additionally operable to treat venomous snake bite, summer-heat damp cold, Meniere disease etc..
C. eupatorium has antitumaous effect.Eupatorium alkaloid shows certain antitumor activity in testing in vitro, to external
The human cervical carcinoma cell of culture has 50% inhibiting rate.In vivo studies shows lumbar injection eupatorium biology total alkali 50mg/kg, continuous 7
Day, the existence time limit of ascitic type S180 sarcoma mouse significantly extends, secondary experiment increase in life span be respectively 33.93% and
44.43%.Lumbar injection or hypodermic injection biology total alkali are shared with endoxan, all can extend Bearing Mice Life, in synergy.
The present invention to 125 cancer cells, 199 cancer cells, small cell carcinoma cell, non-small cell cancer cell, S ascites cells,
Mass-type canceration virus has stronger suppression to kill effect.
Specific embodiment
Below will by embodiment, the invention will be further described, these descriptions are not that present invention is made further
Restriction.Person skilled should be understood that the equivalent that the technical characteristic to the present invention is made, or is correspondingly improved, and still belongs to
Within protection scope of the present invention.
Embodiment 1
Prescription:Reticulate millettia 10g, red sage root 10g, fruit of glossy privet 10g, Radix Astragali 10g, honeysuckle 10g, field pennycress 10g, root of kudzu vine 10g, golden cypress
6g, stem of noble dendrobium 5g, Radix Angelicae Sinensis 8g, root of large-flowered skullcap 6g, kelp 10g, dandelion 10g, eupatorium 10g.(Medicinal material weight 125g).
Preparation method:Take the mixture of described raw medicinal material in proportion, cleaning, 1-3 minute of scalding in 80-100 degree hot water, get rid of
Dry, airing, pulverize through portable pulverizer, cross 140 mesh sieves, mix, steam 30-40 minute, dry, packaging, every bag of 2g.
Embodiment 2
Prescription:Reticulate millettia 13g, red sage root 12g, fruit of glossy privet 12g, Radix Astragali 13g, honeysuckle 13g, field pennycress 13g, root of kudzu vine 13g, golden cypress
8g, stem of noble dendrobium 7g, Radix Angelicae Sinensis 10g, root of large-flowered skullcap 8g, kelp 13g, dandelion 13g, eupatorium 13g.(Medicinal material weight 161g).
Preparation method:Ibid.
Embodiment 3
Prescription:Reticulate millettia 15g, red sage root 13g, fruit of glossy privet 13g, Radix Astragali 15g, honeysuckle 15g, field pennycress 15g, root of kudzu vine 15g, golden cypress
10g, stem of noble dendrobium 8g, Radix Angelicae Sinensis 12g, root of large-flowered skullcap 10g, kelp 15g, dandelion 15g, eupatorium 15g.(Medicinal material weight 186g).
Preparation method:Ibid.
Instructions of taking of the present invention is as follows:
Three times a day, a 4g, continuously takes two months.
Below Chinese herbal medicine for preventing prepared by above-described embodiment is applied in pharmacological research.
Model case is studied:
Case 1:Liu Guiping, female, 58 years old, cervical carcinoma, medical history 5 years.
On October 8th, 2011 finds the cervical carcinoma later stage, and bleeding serious Tianjin center hospital for gynaecology and obstetrics doctor informs that multipotency is lived
10 months.Index for examination cancer antigen 125:71.48, cancer antigen 199:25.66, go home afternoon to start to take the embodiment of the present invention 2
Gained instant particles as Chinese medicine, 3 times a day, one time 4 grams.Continuously take 25 days, cancer antigen 125 drops to 13.93, and cancer antigen 199 is down to
23.84, remove hospital surgical, postoperative see focus with calcification.Examination in hospital is gone to return to one's perfect health after continuing to have taken 2 months.Extremely
Modern health is good.
Case 2:Li Yisheng, man, 62 years old, lung cancer small cell types, medical history 1 year.
On January 5th, 2014 finds lung cancer small cell types in Tianjin tumour hospital, and January 17 took the embodiment of the present invention 2 institute
Instant particles as Chinese medicine, 3 times a day, one time 4 grams, continuously take rehabilitation in 4 months, can normal work, health is good so far.
The present inventor successfully makes pure Chinese medicine electuary that is no added, having no toxic side effect, this Chinese medicine system through years of researches
Agent has anticancer, relieves internal heat, dredging collateral, improves immunity, shield heart, strong kidney, easypro liver, invigorating the spleen, moistening lung, the effect of warm stomach.Solve one
Individual difficult medical problem, brings raw hope to cancer patients such as carcinoma of vagina, cervical carcinoma, lung cancer, the carcinoma of the rectum.
Claims (4)
1. a kind of Chinese herbal medicine for preventing is it is characterised in that be made up of the raw medicinal material of following parts by weight:Reticulate millettia 10-15 part, the red sage root
10-13 part, fruit of glossy privet 10-13 part, Radix Astragali 10-15 part, honeysuckle 10-15 part, field pennycress 10-15 part, root of kudzu vine 10-15 part is yellow
Cypress 6-10 part, stem of noble dendrobium 5-8 part, Radix Angelicae Sinensis 8-12 part, root of large-flowered skullcap 6-10 part, kelp 10-15 part, dandelion 10-15 part, eupatorium 10-15
Part.
2. Chinese herbal medicine for preventing according to claim 1 is it is characterised in that the parts by weight of described each raw medicinal material are:Chicken blood
13 parts of rattan, 12 parts of the red sage root, 12 parts of the fruit of glossy privet, 13 parts of the Radix Astragali, 13 parts of honeysuckle, 13 parts of field pennycress, 13 parts of the root of kudzu vine, 8 parts of golden cypress, stone
7 parts of dry measure used in former times, 10 parts of Radix Angelicae Sinensis, 8 parts of the root of large-flowered skullcap, 13 parts of kelp, 13 parts of dandelion, 13 parts of eupatorium.
3. Chinese herbal medicine for preventing according to claim 1 and 2 is it is characterised in that electuary made by described raw material.
4. Chinese herbal medicine for preventing according to claim 1 and 2 is it is characterised in that take the mixture of described raw medicinal material in proportion,
Cleaning, 1-3 minute of scalding in 80-100 degree hot water, dry, airing, pulverize through portable pulverizer, cross 140 mesh sieves, mix, steam
30-40 minute, dries, packaging, every bag of 2g.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108371664A (en) * | 2018-04-12 | 2018-08-07 | 广东医科大学 | Wogonoside is in the application for preparing anti-rotavirus medicaments |
CN111254182A (en) * | 2020-03-30 | 2020-06-09 | 深圳市兰科植物保护研究中心 | Dendrobe polysaccharide anticancer activity analysis method and application of dendrobe polysaccharide |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103933193A (en) * | 2014-04-29 | 2014-07-23 | 黄葵 | Natural plant type biological anti-cancer medicine |
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2016
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103933193A (en) * | 2014-04-29 | 2014-07-23 | 黄葵 | Natural plant type biological anti-cancer medicine |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108371664A (en) * | 2018-04-12 | 2018-08-07 | 广东医科大学 | Wogonoside is in the application for preparing anti-rotavirus medicaments |
CN111254182A (en) * | 2020-03-30 | 2020-06-09 | 深圳市兰科植物保护研究中心 | Dendrobe polysaccharide anticancer activity analysis method and application of dendrobe polysaccharide |
CN111254182B (en) * | 2020-03-30 | 2024-01-02 | 深圳市兰科植物保护研究中心 | Dendrobium polysaccharide anticancer activity analysis method and application of dendrobium polysaccharide |
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