CN107519406A - Strengthening spleen, tonifying kidney composition and preparation method thereof - Google Patents
Strengthening spleen, tonifying kidney composition and preparation method thereof Download PDFInfo
- Publication number
- CN107519406A CN107519406A CN201710773098.8A CN201710773098A CN107519406A CN 107519406 A CN107519406 A CN 107519406A CN 201710773098 A CN201710773098 A CN 201710773098A CN 107519406 A CN107519406 A CN 107519406A
- Authority
- CN
- China
- Prior art keywords
- parts
- strengthening spleen
- tonifying kidney
- kidney composition
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 87
- 210000003734 kidney Anatomy 0.000 title claims abstract description 74
- 210000000952 spleen Anatomy 0.000 title claims abstract description 67
- 238000005728 strengthening Methods 0.000 title claims abstract description 61
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 44
- 241000237502 Ostreidae Species 0.000 claims abstract description 30
- 235000020636 oyster Nutrition 0.000 claims abstract description 30
- 240000008042 Zea mays Species 0.000 claims abstract description 29
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 28
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 28
- 235000005822 corn Nutrition 0.000 claims abstract description 28
- 241000234435 Lilium Species 0.000 claims abstract description 24
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 23
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 23
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 23
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 23
- 240000000249 Morus alba Species 0.000 claims abstract description 23
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 23
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 23
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 23
- 235000011034 Rubus glaucus Nutrition 0.000 claims abstract description 23
- 244000235659 Rubus idaeus Species 0.000 claims abstract description 23
- 235000009122 Rubus idaeus Nutrition 0.000 claims abstract description 23
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims abstract description 22
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims abstract description 22
- 235000009685 Crataegus X maligna Nutrition 0.000 claims abstract description 22
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims abstract description 22
- 235000009486 Crataegus bullatus Nutrition 0.000 claims abstract description 22
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims abstract description 22
- 235000009682 Crataegus limnophila Nutrition 0.000 claims abstract description 22
- 235000004423 Crataegus monogyna Nutrition 0.000 claims abstract description 22
- 235000002313 Crataegus paludosa Nutrition 0.000 claims abstract description 22
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims abstract description 22
- 244000241872 Lycium chinense Species 0.000 claims abstract description 21
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 240000000171 Crataegus monogyna Species 0.000 claims abstract 4
- 239000000284 extract Substances 0.000 claims description 56
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
- 239000000706 filtrate Substances 0.000 claims description 26
- 240000008866 Ziziphus nummularia Species 0.000 claims description 25
- 239000002245 particle Substances 0.000 claims description 13
- 239000004383 Steviol glycoside Substances 0.000 claims description 12
- 229930182488 steviol glycoside Natural products 0.000 claims description 12
- 235000019411 steviol glycoside Nutrition 0.000 claims description 12
- 150000008144 steviol glycosides Chemical class 0.000 claims description 12
- 235000019202 steviosides Nutrition 0.000 claims description 12
- 229920002774 Maltodextrin Polymers 0.000 claims description 11
- 239000005913 Maltodextrin Substances 0.000 claims description 11
- 229940035034 maltodextrin Drugs 0.000 claims description 11
- 238000012545 processing Methods 0.000 claims description 10
- 238000000605 extraction Methods 0.000 claims description 8
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 7
- 229920001353 Dextrin Polymers 0.000 claims description 7
- 239000004375 Dextrin Substances 0.000 claims description 7
- 235000019425 dextrin Nutrition 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 6
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 6
- 239000006071 cream Substances 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 5
- 230000003179 granulation Effects 0.000 claims description 5
- 239000007779 soft material Substances 0.000 claims description 5
- 238000010025 steaming Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 3
- 239000011122 softwood Substances 0.000 claims description 3
- 238000001291 vacuum drying Methods 0.000 claims description 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 23
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 244000126002 Ziziphus vulgaris Species 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 241001092040 Crataegus Species 0.000 description 18
- 239000008280 blood Substances 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 230000000694 effects Effects 0.000 description 10
- 208000024891 symptom Diseases 0.000 description 10
- 239000003814 drug Substances 0.000 description 9
- 201000010099 disease Diseases 0.000 description 8
- 210000004185 liver Anatomy 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 230000035900 sweating Effects 0.000 description 6
- 239000000686 essence Substances 0.000 description 5
- 235000013305 food Nutrition 0.000 description 5
- 238000010791 quenching Methods 0.000 description 5
- 230000002269 spontaneous effect Effects 0.000 description 5
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 4
- 235000017491 Bambusa tulda Nutrition 0.000 description 4
- 244000082204 Phyllostachys viridis Species 0.000 description 4
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 4
- 239000011425 bamboo Substances 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 239000010977 jade Substances 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 210000000582 semen Anatomy 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 235000013339 cereals Nutrition 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 230000035922 thirst Effects 0.000 description 3
- 235000020985 whole grains Nutrition 0.000 description 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 208000001953 Hypotension Diseases 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 244000241838 Lycium barbarum Species 0.000 description 2
- 235000015459 Lycium barbarum Nutrition 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 241000037826 Polygonatum kingianum Species 0.000 description 2
- 241000219780 Pueraria Species 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 239000011651 chromium Substances 0.000 description 2
- 229910052804 chromium Inorganic materials 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 235000003642 hunger Nutrition 0.000 description 2
- 208000021822 hypotensive Diseases 0.000 description 2
- 230000001077 hypotensive effect Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 229930182490 saponin Natural products 0.000 description 2
- 150000007949 saponins Chemical class 0.000 description 2
- 239000002893 slag Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 210000002237 B-cell of pancreatic islet Anatomy 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 208000002249 Diabetes Complications Diseases 0.000 description 1
- 206010012655 Diabetic complications Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000006083 Hypokinesia Diseases 0.000 description 1
- 206010054949 Metaplasia Diseases 0.000 description 1
- 241001468611 Polygonatum cyrtonema Species 0.000 description 1
- 241000037831 Polygonatum sibiricum Species 0.000 description 1
- 206010067868 Skin mass Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 description 1
- 235000007244 Zea mays Nutrition 0.000 description 1
- 208000011279 abdominal lump Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- LPQOADBMXVRBNX-UHFFFAOYSA-N ac1ldcw0 Chemical compound Cl.C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3CCSC1=C32 LPQOADBMXVRBNX-UHFFFAOYSA-N 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 229940089639 cornsilk Drugs 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000015689 metaplastic ossification Effects 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 238000003359 percent control normalization Methods 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000000291 postprandial effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 238000012958 reprocessing Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000001231 zea mays silk Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a kind of strengthening spleen, tonifying kidney composition and preparation method thereof, wherein, the strengthening spleen, tonifying kidney composition is made up of the raw material of following mass parts:150~180 parts of 90~110 parts of the fruit of Chinese wolfberry, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma.Strengthening spleen, tonifying kidney composition provided by the invention is mixed by kinds of traditional Chinese medicines, and sugar content is low, is beneficial to diabetic's use.
Description
Technical field
The present invention relates to food processing technology field, and in particular to a kind of strengthening spleen, tonifying kidney composition and preparation method thereof.
Background technology
In recent years, the disease such as diabetes, hypertension and hyperlipidemia rises rapidly, and such disease is considered as and diet style
Closely related, prior art is proved in terms of can preventing this kind of disease by improving dietetic life.Diabetes (Diabetes
Mellitus, DM) by the caused endocrine metabolism using hyperglycaemia as common trait of the insulin reduction of pancreatic beta cell secretion
Disorder disease, it is referred to as " diabete " in the traditional Chinese medical science.Diabetes are often accompanied by serious complication, have a strong impact on diabetic's
Life.
Because the blood-sugar content in diabetic's body is unstable, it is necessary to Tighter control, the higher food of general sugar
Product are it is not recommended that edible.And the existing food lacked on the market with certain curative effect effect and suitable for patients with diabetes mellitus.
It is therefore desirable to provide a kind of food for adapting to patients with diabetes mellitus.
The content of the invention
The main object of the present invention is to provide a kind of strengthening spleen, tonifying kidney composition, with suitable for patients with diabetes mellitus.
To achieve the above object, strengthening spleen, tonifying kidney composition proposed by the present invention is made up of the raw material of following mass parts:Matrimony vine
90~110 parts of son, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, hawthorn 90
~110 parts, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, jujube 90~110
150~180 parts of part, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma.
Preferably, the sealwort is the steaming sealwort by processing.
Preferably, the oyster is the calcined oyster shell by processing.
Preferably, the spina date seed is the Semen Ziziphi Spinosae (parched) by processing.
Preferably, the strengthening spleen, tonifying kidney composition is form of powdery particles, also include in the strengthening spleen, tonifying kidney composition dextrin,
Maltodextrin and steviol glycoside.
The present invention also provides a kind of preparation method of strengthening spleen, tonifying kidney composition, comprises the following steps:
Step 1:By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, system
90~110 parts of dark plum, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, raspberry
90~110 parts, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam, corn stigma 150
~180 parts and water are added in extractor and extracted, and obtain extract solution;
Step 2:Steviol glycoside is added in the extract solution that the step 1 obtains, be concentrated under reduced pressure to obtain thick paste;
Step 3:Obtained thick paste in the step 2 is dried, dry cream is made, adds maltodextrin and dextrin,
Crushed after well mixed, add soft material granulation processed, and fluidized drying, the strengthening spleen, tonifying kidney composition of form of powdery particles is made.
Preferably, the concrete operations of the step 1 are:
By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, dark plum processed 90~
110 parts, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, raspberry 90~110
150~180 parts of part, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma
Mixture is mixed and made into, mixture and the first mass parts water are added in extractor and carry out first time extraction and obtain to extract for the first time
Thing;
First extract is filtered, obtains first filtrate and the first dregs of a decoction respectively, the first dregs of a decoction are placed in extractor
In and add the second mass parts water, extracted for the second time and obtain second extract;
Second extract is filtered, obtains secondary filtrate and the secondary dregs of a decoction respectively, by first filtrate and secondary filtrate
Merge and obtain the extract solution.
Preferably, the first mass parts water is 8~10 times of amounts of the gross mass of mixture in the step 1;The step 2
In the second mass parts water for mixture 5~6 times of gross mass amounts.
Preferably, the temperature being concentrated under reduced pressure in the step 2 be 60 DEG C~70 DEG C, pressure value be -0.06MPa~-
0.08MPa;Thick paste is dried in vacuo in the step 3, vacuum drying temperature be 60 DEG C~70 DEG C, pressure value for-
0.06MPa~-0.08MPa.
Preferably, the softwood processed in the step 3 is the ethanol water that concentration is 90%~95%.
Strengthening spleen, tonifying kidney composition sugar content in the present invention is low, mouthfeel is good, suitable for patients with diabetes mellitus.By using Pueraria lobota
Root promotes the production of body fluid to quench thirst, to solve disappearing for the part of the body cavity above the diaphragm housing the heart and lungs;Radix polygonati officinalis, lily yin-nourishing increase liquid, share disappearing with Xie Zhongjiao;Chinese yam, jujube tonifying spleen lung kidney
Gas;Yijing blood that sealwort, the fruit of Chinese wolfberry, mulberry fruit, spina date seed are nourishing liver and kidney;Raspberry warms up kidney Wen Yang, and oyster is reinforced the kidney contracting spring, above conjunction
To take off the sorrow of Jiao.Corn stigma inducing diuresis for removing edema, hypotensive;Hawthorn disappears many stomach invigoratings, scattered stasis, changes turbid lipid-loweringing, to prevent in side
Flavour of a drug grow greasy property.All medicines share, resolving and invigoration therapies being applied simultaneously, Jiao of upper, middle and lower three lay equal stress on, and negative and positive of qi and blood is taken into account, and plays lung-clearing thirst-quenching, clearing stomach altogether
Stay one's hunger, the astringent or styptic treatment for spontaneous sweating effect of kidney tonifying.
Embodiment
The technical scheme in the embodiment of the present invention will be clearly and completely described below, it is clear that described implementation
Example is only the part of the embodiment of the present invention, rather than whole embodiments.It is general based on the embodiment in the present invention, this area
The every other embodiment that logical technical staff is obtained under the premise of creative work is not made, belong to what the present invention protected
Scope.
In addition, the technical scheme between each embodiment of the present invention can be combined with each other, but must be general with this area
Logical technical staff can be implemented as basis, will be understood that when the combination appearance of technical scheme is conflicting or can not realize this
The combination of technical scheme is not present, also not within the protection domain of application claims.
The present invention proposes a kind of strengthening spleen, tonifying kidney composition, and the strengthening spleen, tonifying kidney composition is made up of the raw material of following mass parts:
90~110 parts of the fruit of Chinese wolfberry, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, mountain
90~110 parts of short, bristly hair or beard, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, jujube 90
~110 parts, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam, 150~180 parts of corn stigma.
Preferably, the strengthening spleen, tonifying kidney composition is made up of the raw material of following mass parts:99 parts of the fruit of Chinese wolfberry, 118.8 parts of mulberry fruit,
99 parts of sealwort, 99 parts of dark plum processed, 99 parts of radix polygonati officinalis, 99 parts of hawthorn, 79.2 parts of oyster, 79.2 parts of spina date seed, 99 parts of raspberry, lily
165 parts of 99 parts, 99 parts of jujube, 99 parts of the root of kudzu vine, 118.8 parts of Chinese yam and corn stigma.
Traditional Chinese medicine thinks, The spleen has the function to transport and transform nutrients trough, metaplasia qi and blood, is " the foundation of acquired constitution ";Kidney storing essence, main production, development and life
Grow, be " the congenital foundation ".Diabetes are referred to as quenching one's thirst in traditional Chinese medicine, to drink more, more food, diuresis, it is weak, become thin as main table
Existing, deficiency of spleen and stomach is closely related with diabetes.Promoted the production of body fluid to quench thirst in strengthening spleen, tonifying kidney composition in the present invention by using the root of kudzu vine, with
The solution part of the body cavity above the diaphragm housing the heart and lungs disappears;Radix polygonati officinalis, lily yin-nourishing increase liquid, share disappearing with Xie Zhongjiao;Chinese yam, jujube tonifying spleen lung kidney qi;Sealwort, matrimony vine
Yijing blood that son, mulberry fruit, spina date seed are nourishing liver and kidney;Raspberry warms up kidney Wen Yang, and oyster is reinforced the kidney contracting spring, is shared above to take off Jiao's
Sorrow.Corn stigma inducing diuresis for removing edema, hypotensive;Hawthorn disappears many stomach invigoratings, scattered stasis, changes turbid lipid-loweringing, and greasy property is grown to prevent square taste of traditional Chinese medicine.
All medicines share, resolving and invigoration therapies being applied simultaneously, Jiao of upper, middle and lower three lay equal stress on, and negative and positive of qi and blood is taken into account, and plays lung-clearing thirst-quenching altogether, and clearing stomach is stayed one's hunger, and kidney tonifying is astringent or styptic treatment for spontaneous sweating
Effect.
It should be noted that contribute to the blood glucose of prevention reduction diabetic using corn stigma in the present invention.Corn
Containing a variety of chemical compositions beneficial to human body in palpus, such as saponin, flavones, alkaloid, organic acid, volatile oil, trace element and more
Kind vitamin.Saponin in corn stigma is the main component for reducing diabetes patient blood sugar.Contain chromium in corn stigma, chromium is that sugar is resistance to
The part of the factor is measured, insulin function can be strengthened.The content of Flavonoid substances is 15 times of iblet in corn stigma, its
The generation of free radical can be reduced and remove free radical, there is good oxidation resistance, and corn silk water extract is removed certainly
Isoflavones is higher than by the ability of base, diabetic complication can be prevented.
Wherein, the sealwort is the steaming sealwort by processing, and the oyster is to pass through the calcined oyster shell processed, the spina date seed
For by the Semen Ziziphi Spinosae (parched) processed.
Sealwort is liliaceous plant P. kingianum (Polygonatumkingianum Coll.et Hemsl.), sealwort
(Polygonatumsibiricum Red.) or the dry rhizome of David's-harp (Polygonatumcyrtonema Hua).It is yellow
Polyoses content is higher in essence, and it is strengthening spleen, tonifying kidney composition that sealwort is made into steaming sealwort reprocessing, compared to raw sealwort, is steamed in sealwort
Polysaccharide hydrolyzable be oligosaccharide and monose, be on the one hand advantageous to the performance of drug effect, be on the other hand advantageous to diabetic suction
Receive metabolism.
Oyster (ostreagigasthunberg), its taste is salty, cold nature, enters kidney Liver Channel.Function is transquilization with heavy material, and checking exuberance of yang is mended
The moon, softening and resolving hard mass, convergence is astringent or styptic treatment for spontaneous sweating, relieving haperacidity analgesic.Oyster cures mainly insomnia of palpitating with fear, dizziness and tinnitus, scrofula subcutaneous nodule , abdominal lump of mass in abdomen, from
The illness such as band, stomachache pantothenic acid is collapsed in sweat night sweat, seminal emission.Oyster obtains calcined oyster shell after processing, and compared to oyster, calcined oyster shell is strengthened
Convergence astringent or styptic treatment for spontaneous sweating effectiveness.Diabetic generally entails gastrointestinal symptoms, and intractable diarrhea is the protrusion of part of diabetes mellitus patient
Diarrhoea occurs in symptom, the diabetes patient that there are about 20%.By adding calcined oyster shell in strengthening spleen, tonifying kidney composition in the present invention,
On the one hand the symptom of diarrhea of diabetic can be alleviated, while another aspect radix polygonati officinalis, lily, the root of kudzu vine have tonifying yin effect, also
With certain de'collement, calcined oyster shell, which restrains astringent or styptic treatment for spontaneous sweating effectiveness, can reduce radix polygonati officinalis, lily, de'collement caused by the root of kudzu vine.
In theory of traditional Chinese medical science, raw and fried sweet acid and moisten, be used for the card of liver and gall abnormal heat, the raw effect promoted the production of body fluid with clearind deficient heat partially
By force.Semen Ziziphi Spinosae (parched) acid Wen Erxiang, has the effect of being amusing concurrently, partially for liver, courage, the heart, the card that the spleen deficiency of blood is slept less.Compared to raw wild jujube
Benevolence, fry the effect enhancing that wild jujube acid convergence stops abnormal sweating;In addition, the Semen Ziziphi Spinosae (parched) obtained by processing is more fragrant, perfume (or spice) can be amusing,
On the one hand absorption of the stomach and intestine to medicine can be promoted, is on the other hand beneficial to the mouthfeel for increasing strengthening spleen, tonifying kidney composition.
Further, the strengthening spleen, tonifying kidney composition is form of powdery particles, also includes paste in the strengthening spleen, tonifying kidney composition
Essence, maltodextrin and steviol glycoside.The calorific value of steviol glycoside is only the 1/300 of sucrose, is not absorbed, not produced after taking in human body
Heat, it is free of a burden after diabetes patient so as to improve the mouthfeel of the strengthening spleen, tonifying kidney composition.By by the strengthening spleen, tonifying kidney
Form of powdery particles is made in composition, is watered after brewing i.e. edible, easy to carry.
Strengthening spleen, tonifying kidney composition proposed by the present invention and preparation method thereof is carried out specifically below by way of specific embodiment
It is bright:
Embodiment one
A kind of strengthening spleen, tonifying kidney composition, the raw material of following mass parts are made:100 parts of the fruit of Chinese wolfberry, 120 parts of mulberry fruit, sealwort 100
Part, 100 parts of dark plum processed, 100 parts of radix polygonati officinalis, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily,
165 parts of 100 parts of jujube, 100 parts of the root of kudzu vine, 120 parts of Chinese yam and corn stigma.
The preparation method of the strengthening spleen, tonifying kidney composition comprises the following steps:
Step S11, by 100 parts of the fruit of Chinese wolfberry of following mass parts, 120 parts of mulberry fruit, 100 parts of sealwort, 100 parts of dark plum processed, jade
100 parts of bamboo, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily, 100 parts of jujube, the root of kudzu vine 100
Part, 120 parts of Chinese yam, 165 parts of corn stigma and water are added in extractor and extracted, and obtain extract solution;
Step S111, by 100 parts of the fruit of Chinese wolfberry of following mass parts, 120 parts of mulberry fruit, 100 parts of sealwort, 100 parts of dark plum processed, jade
100 parts of bamboo, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily, 100 parts of jujube, the root of kudzu vine 100
Part, 165 parts of 120 parts of Chinese yam and corn stigma be mixed and made into mixture, mixture and the first mass parts water are added in extractor
Row extracts for the first time and obtains first extract;
Specifically, above-mentioned each composition is weighed respectively with mass parts:100 parts of the fruit of Chinese wolfberry, 120 parts of mulberry fruit, 100 parts of sealwort, system
100 parts of dark plum, 100 parts of radix polygonati officinalis, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily, jujube
165 parts of 100 parts, 100 parts of the root of kudzu vine, 120 parts of Chinese yam and corn stigma, said mixture is placed in extractor, adds above-mentioned mixing
The pure water of 9 times of amounts of thing gross mass, it is 100 DEG C to set Extracting temperature, Dynamic Extraction 120 minutes, obtains first extract.
Step S112, is filtered to first extract, obtains first filtrate and the first dregs of a decoction respectively, and the first dregs of a decoction are put
In extractor and the second mass parts water is added, is extracted for the second time and obtains second extract;
Specifically, the mesh filtered through gauze of first extract 200 that will be obtained in step S111, obtain respectively first filtrate and just
The secondary dregs of a decoction, the first dregs of a decoction are placed in extractor and add the water of 5.5 times of amounts of said mixture gross mass, and setting Extracting temperature is
100 DEG C, Dynamic Extraction 60 minutes, extracted for the second time and obtain second extract
Step S113, the step S112 second extracts obtained are filtered, obtain secondary filtrate and secondary medicine respectively
Slag, first filtrate is merged with secondary filtrate and obtains the extract solution.
Specifically, the mesh filtered through gauze of second extract 200 obtained to step S112, secondary filtrate and secondary is obtained respectively
The dregs of a decoction.
Step S12, steviol glycoside is added in the extract solution that the step S11 is obtained, be concentrated under reduced pressure to obtain thick paste;
Specifically, in the extract solution obtained in the step S113 add 7 parts of steviol glycoside, pressure value for-
0.07MPa, temperature are concentrated under reduced pressure under the conditions of being 65 DEG C, obtain the thick paste that relative density is 1.25-1.3;
Step S13, obtained thick paste in the step S12 is dried, dry cream is made, add maltodextrin and paste
Essence, crushed after well mixed, add soft material granulation processed, and the strengthening spleen, tonifying kidney composition of the form of powdery particles of fluidized drying.
Specifically, thick paste is dried in vacuo under the conditions of pressure value is -0.07MPa, temperature is 65 DEG C, got dry extract,
600 parts of 60 parts of maltodextrin and dextrin are added, is crushed after well mixed, the ethanol water that concentration is 93% is added and pelletizes, and
Fluidized drying to water content is less than 5%, 12 mesh sieve whole grains, obtains 1000 parts of the strengthening spleen, tonifying kidney composition grain of form of powdery particles.
It is understood that can also use spray drying to thick paste, those skilled in the art can enter according to actual conditions
Row selection.
It is softwood processed to add the ethanol water that concentration is 93%, and the thick paste for making to make in step S2 has certain viscosity and wet
Degree, so that form of powdery particles is suitably made.
Embodiment two
A kind of strengthening spleen, tonifying kidney composition, the raw material of following mass parts are made:90 parts of the fruit of Chinese wolfberry, 110 parts of mulberry fruit, sealwort 90
Part, 90 parts of dark plum processed, 90 parts of radix polygonati officinalis, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, jujube
150 parts of 90 parts, 90 parts of the root of kudzu vine, 170 parts of Chinese yam and corn stigma.
The preparation method of the strengthening spleen, tonifying kidney composition comprises the following steps:
Step S21, by 90 parts of the fruit of Chinese wolfberry of following mass parts, 110 parts of mulberry fruit, 90 parts of sealwort, 90 parts of dark plum processed, radix polygonati officinalis 90
Part, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, 90 parts of jujube, 90 parts of the root of kudzu vine, Chinese yam 170
Part, 150 parts of corn stigma and water are added in extractor and extracted, and obtain extract solution;
Step S211, by 90 parts of the fruit of Chinese wolfberry of following mass parts, 110 parts of mulberry fruit, 90 parts of sealwort, 90 parts of dark plum processed, radix polygonati officinalis
90 parts, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, 90 parts of jujube, 90 parts of the root of kudzu vine, Chinese yam
170 parts and 150 parts of corn stigma are mixed and made into mixture, and mixture and the first mass parts water are added in extractor and carried out for the first time
Extract and obtain first extract;
Specifically, above-mentioned each composition is weighed respectively with mass parts:90 parts of the fruit of Chinese wolfberry, 110 parts of mulberry fruit, 90 parts of sealwort, system crow
90 parts of plum, 90 parts of radix polygonati officinalis, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, 90 parts of jujube, Pueraria lobota
90 parts of root, 170 parts of Chinese yam, 150 parts of corn stigma, said mixture is placed in extractor, adds 8 times of said mixture gross mass
The water of amount, it is 90 DEG C to set Extracting temperature, Dynamic Extraction 140 minutes, obtains first extract.
Step S212, is filtered to first extract, obtains first filtrate and the first dregs of a decoction respectively, and the first dregs of a decoction are put
In extractor and the second mass parts water is added, is extracted for the second time and obtains second extract;
Specifically, the mesh filtered through gauze of first extract 200 that will be obtained in step S211, obtain respectively first filtrate and just
The secondary dregs of a decoction, the first dregs of a decoction are placed in extractor and add the water of 5 times of amounts of said mixture gross mass, it is 90 to set Extracting temperature
DEG C, Dynamic Extraction 70 minutes, extracted for the second time and obtain second extract
Step S213, the step S212 second extracts obtained are filtered, obtain secondary filtrate and the dregs of a decoction respectively, will
First filtrate merges with secondary filtrate obtains the extract solution.
Specifically, the mesh filtered through gauze of second extract 200 obtained to step S212, secondary filtrate and secondary is obtained respectively
The dregs of a decoction.
Step S22, steviol glycoside is added in the extract solution that the step S21 is obtained, be concentrated under reduced pressure to obtain thick paste;
Specifically, in the extract solution obtained in the step S213 add 6 parts of steviol glycoside, pressure value for-
0.06MPa, temperature are concentrated under reduced pressure under the conditions of being 60 DEG C, obtain the thick paste that relative density is 1.20-1.25;
Step S23, obtained thick paste in the step S22 is dried, dry cream is made, add maltodextrin and paste
Essence, crushed after well mixed, add soft material granulation processed, and the strengthening spleen, tonifying kidney composition of the form of powdery particles of fluidized drying.
Specifically, thick paste is dried in vacuo under the conditions of pressure value is -0.06MPa, temperature is 60 DEG C, got dry extract,
580 parts of 55 parts of maltodextrin and dextrin are added, is crushed after well mixed, concentration is added and is pelletized for 90% ethanol water, and boil
Rise to dry to water content and be less than 5%, 12 mesh sieve whole grains, obtain 1000 parts of the strengthening spleen, tonifying kidney composition grain of form of powdery particles.
Embodiment three
A kind of strengthening spleen, tonifying kidney composition, the raw material of following mass parts are made:110 parts of the fruit of Chinese wolfberry, 130 parts of mulberry fruit, sealwort 110
Part, 110 parts of dark plum processed, 110 parts of radix polygonati officinalis, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily,
180 parts of 110 parts of jujube, 110 parts of the root of kudzu vine, 130 parts of Chinese yam and corn stigma.
The preparation method of the strengthening spleen, tonifying kidney composition comprises the following steps:
Step S31, by 110 parts of the fruit of Chinese wolfberry of following mass parts, 130 parts of mulberry fruit, 110 parts of sealwort, 110 parts of dark plum processed, jade
110 parts of bamboo, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily, 110 parts of jujube, the root of kudzu vine 110
Part, 130 parts of Chinese yam, 180 parts of corn stigma and water are added in extractor and extracted, and obtain extract solution;
Step S311, by 110 parts of the fruit of Chinese wolfberry of following mass parts, 130 parts of mulberry fruit, 110 parts of sealwort, 110 parts of dark plum processed, jade
110 parts of bamboo, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily, 110 parts of jujube, the root of kudzu vine 110
Part, 180 parts of 130 parts of Chinese yam and corn stigma be mixed and made into mixture, mixture and the first mass parts water are added in extractor
Row extracts for the first time and obtains first extract;
Specifically, above-mentioned each composition is weighed respectively with mass parts:110 parts of the fruit of Chinese wolfberry, 130 parts of mulberry fruit, 110 parts of sealwort, system
110 parts of dark plum, 110 parts of radix polygonati officinalis, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily, jujube
110 parts, 110 parts of the root of kudzu vine, 130 parts of Chinese yam, 180 parts of corn stigma, said mixture is placed in extractor, add said mixture
The water of 10 times of amounts of gross mass, it is 100 DEG C to set Extracting temperature, Dynamic Extraction 110 minutes, obtains first extract.
Step S312, is filtered to first extract, obtains first filtrate and the first dregs of a decoction respectively, and the first dregs of a decoction are put
In extractor and the second mass parts water is added, is extracted for the second time and obtains second extract;
Specifically, the mesh gauze of first extract 200 obtained in step S311 is filtered, obtains first filtrate respectively
With the first dregs of a decoction, the first dregs of a decoction are placed in extractor and add the water of 6 times of amounts of said mixture gross mass, Extracting temperature is set
For 100 DEG C, Dynamic Extraction 50 minutes, extracted for the second time and obtain second extract
Step S313, the step S312 second extracts obtained are filtered, obtain secondary filtrate and secondary medicine respectively
Slag, first filtrate is merged with secondary filtrate and obtains the extract solution.
Specifically, the mesh filtered through gauze of second extract 200 obtained to step S312, secondary filtrate and secondary is obtained respectively
The dregs of a decoction.
Step S32, steviol glycoside is added in the extract solution that the step S31 is obtained, be concentrated under reduced pressure to obtain thick paste;
Specifically, in the extract solution obtained in the step S313 add 8 parts of steviol glycoside, pressure value for-
0.08MPa, temperature are concentrated under reduced pressure under the conditions of being 70 DEG C, obtain the thick paste that relative density is 1.25-1.3;
Step S33, obtained thick paste in the step S32 is dried, dry cream is made, add maltodextrin and paste
Essence, crushed after well mixed, add soft material granulation processed, and the strengthening spleen, tonifying kidney composition of the form of powdery particles of fluidized drying.
Specifically, thick paste is dried in vacuo under the conditions of pressure value is -0.08MPa, temperature is 70 DEG C, got dry extract,
630 parts of 65 parts of maltodextrin and dextrin are added, is crushed after well mixed, concentration is added and is pelletized for 95% ethanol water, and boil
Rise to dry to water content and be less than 5%, 12 mesh sieve whole grains, obtain 1000 parts of the strengthening spleen, tonifying kidney composition grain of form of powdery particles.
There is certain prevention, intervention effect to diabetes to illustrate strengthening spleen, tonifying kidney composition of the present invention, with by above-mentioned
Strengthening spleen, tonifying kidney composition is tested made from method in embodiment 1~3, to prove that it has certain prevention, intervention effect,
But it can not form any restrictions to the scope of the present invention.
It is each 80 of 50~60 years old men and women for meeting type II diabetes to select the age, is divided into 4 groups, each group includes 20 men
Property, 20 women.1st group totally 40, man 20, female 20, the age be (55.18 ± 2.37) year, the course of disease for (18.79 ±
28.39) individual month, strengthening spleen, tonifying kidney composition made from the method in embodiment 1 is eaten;2nd group totally 40, man 20, female 20,
Age be (53.17 ± 2.21) year, the course of disease is (20.19 ± 28.11) individual month, strengthening spleen, tonifying kidney made from the method in embodiment 2
Composition;3rd group totally 40, man 20, female 20, the age be (54.56 ± 3.56) year, the course of disease be (19.33 ± 27.16) it is individual
Month, eat strengthening spleen, tonifying kidney composition made from the method in embodiment 3;4th group totally 40, man 20, female 20, the age is
In (53.89 ± 2.65) year, the course of disease is (20.35 ± 28.21) individual month edible placebo.During experiment, everyone is every for experimental group
Day respectively takes the strengthening spleen, tonifying kidney composition of the 10g present invention for 1 hour before meals sooner or later.Through statistics, two groups in sex, age, course of disease etc.
There was no significant difference for aspect (P > 0.05), has comparativity.Exclusion standard:(1) IDDM patient;(2) with severe cardiac,
Liver and kidney function is not complete and acute infection patient;(3) nursing period, pregnancy women.
Table 1 is referred to, table 1 is to eat the effect research table after strengthening spleen, tonifying kidney composition of the present invention.Wherein, with thirsty more
Drink, polyorexia, dysphoria in chestpalms-soles, lassitude hypodynamia are that symptom is scored, and symptom efficacy evaluation is classified by level Four point system:0 (nothing
Symptom), 1 (can sensory symptoms presence when must be through reminding), 2 (having symptom sometimes), 3 (symptom is obvious), and carry out symptom score
And integration.≤ 4 points of scoring is effective, and 4 < score≤8 points, is effective;It is invalid that scoring, which is more than 8 points,.
Table 1 eats the effect research table after strengthening spleen, tonifying kidney composition of the present invention
Group | Number of cases | It is effective | Effectively | It is invalid | Total effective rate |
Embodiment 1 | 40 | 17 | 21 | 2 | 95.0% |
Embodiment 2 | 40 | 17 | 20 | 3 | 92.5% |
Embodiment 3 | 40 | 14 | 25 | 1 | 97.5% |
Control group | 40 | 8 | 6 | 26 | 35.0% |
Table 2 is referred to, table 2 is to eat the blood sugar test table after strengthening spleen, tonifying kidney composition of the present invention.Experimental subjects is detected
FPG (fasting blood-glucose), P2hPG (postprandial 2 hours blood glucose).
Table 2 eats the blood sugar test table after strengthening spleen, tonifying kidney composition of the present invention
The strengthening spleen, tonifying kidney composition that can be observed to prepare in embodiment 1~3 by table 2 eats invigorating the spleen and mended compared with control group
Patient FPG, P2hPG value of kidney composition reduce (P < 0.05).
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the scope of the invention, it is every at this
Under the inventive concept of invention, the equivalent structure transformation made using description of the invention, or directly/to be used in other indirectly related
Technical field be included in the present invention scope of patent protection in.
Claims (10)
1. a kind of strengthening spleen, tonifying kidney composition, it is characterised in that it is made up of the raw material of following mass parts:90~110 parts of the fruit of Chinese wolfberry,
110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, oyster
70~90 parts, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, 90~110 parts of jujube, the root of kudzu vine 90~
150~180 parts of 110 parts, 110~130 parts of Chinese yam and corn stigma.
2. strengthening spleen, tonifying kidney composition as claimed in claim 1, it is characterised in that the sealwort is the steaming sealwort by processing.
3. strengthening spleen, tonifying kidney composition as claimed in claim 1, it is characterised in that the oyster is the calcined oyster shell by processing.
4. strengthening spleen, tonifying kidney composition as claimed in claim 1, it is characterised in that the spina date seed is the stir-fry wild jujube by processing
Benevolence.
5. the strengthening spleen, tonifying kidney composition as any one of Claims 1-4, it is characterised in that the strengthening spleen, tonifying kidney combination
Thing is form of powdery particles, and dextrin, maltodextrin and steviol glycoside are also included in the strengthening spleen, tonifying kidney composition.
6. a kind of preparation method of strengthening spleen, tonifying kidney composition, it is characterised in that comprise the following steps:
Step 1:By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, dark plum processed
90~110 parts, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, raspberry 90~
110 parts, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam, corn stigma 150~180
Part and water, which are added in extractor, to be extracted, and obtains extract solution;
Step 2:Steviol glycoside is added in the extract solution that the step 1 obtains, be concentrated under reduced pressure to obtain thick paste;
Step 3:Obtained thick paste in the step 2 is dried, dry cream is made, adds maltodextrin and dextrin, mixing
Crushed after uniformly, add soft material granulation processed, and fluidized drying, the strengthening spleen, tonifying kidney composition of form of powdery particles is made.
7. the preparation method of strengthening spleen, tonifying kidney composition as claimed in claim 6, it is characterised in that the specific behaviour of the step 1
As:
By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, dark plum processed 90~110
Part, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, hundred
150~180 parts of 90~110 parts of conjunction, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma mixing
Mixture is made, mixture and the first mass parts water are added in extractor and carries out first time extraction and obtains first extract;
First extract is filtered, obtains first filtrate and the first dregs of a decoction respectively, the first dregs of a decoction are placed in extractor simultaneously
The second mass parts water is added, is extracted for the second time and obtains second extract;
Second extract is filtered, obtains secondary filtrate and the secondary dregs of a decoction respectively, first filtrate is merged with secondary filtrate
Obtain the extract solution.
8. the preparation method of strengthening spleen, tonifying kidney composition as claimed in claim 7, it is characterised in that the first matter in the step 1
Measure 8~10 times amounts of part water for the gross mass of mixture;The second mass parts water is the 5 of the gross mass of mixture in the step 2
~6 times of amounts.
9. the preparation method of strengthening spleen, tonifying kidney composition as claimed in claim 6, it is characterised in that depressurized in the step 2 dense
The temperature of contracting is 60 DEG C~70 DEG C, and pressure value is -0.06MPa~-0.08MPa;Vacuum is carried out in the step 3 to thick paste to do
Dry, vacuum drying temperature is 60 DEG C~70 DEG C, and pressure value is -0.06MPa~-0.08MPa.
10. the preparation method of the strengthening spleen, tonifying kidney composition as any one of claim 6 to 9, it is characterised in that the step
Softwood processed in rapid three is the ethanol water that concentration is 90%~95%.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710773098.8A CN107519406A (en) | 2017-08-31 | 2017-08-31 | Strengthening spleen, tonifying kidney composition and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710773098.8A CN107519406A (en) | 2017-08-31 | 2017-08-31 | Strengthening spleen, tonifying kidney composition and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107519406A true CN107519406A (en) | 2017-12-29 |
Family
ID=60683075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710773098.8A Pending CN107519406A (en) | 2017-08-31 | 2017-08-31 | Strengthening spleen, tonifying kidney composition and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107519406A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109464598A (en) * | 2018-12-28 | 2019-03-15 | 贵州爱多康生物科技有限公司 | A kind of composition and preparation method thereof containing Acer truncatum leaves for health drink |
CN113785981A (en) * | 2021-10-14 | 2021-12-14 | 潘学群 | Health-preserving medicinal and edible composition and preparation method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103859378A (en) * | 2012-12-10 | 2014-06-18 | 天津红日药业股份有限公司 | Formula and preparation method of life cultivation and health preservation food helpful for reducing blood sugar |
CN104547547A (en) * | 2014-12-30 | 2015-04-29 | 兰州古驰生物科技有限公司 | Traditional Chinese medicine preparation used for comprehensively conditioning health of five internal organs |
CN106728868A (en) * | 2016-12-28 | 2017-05-31 | 陕西红顶名医堂药业有限公司 | Chinese medicine composition and preparation method thereof for treating diabetes |
-
2017
- 2017-08-31 CN CN201710773098.8A patent/CN107519406A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103859378A (en) * | 2012-12-10 | 2014-06-18 | 天津红日药业股份有限公司 | Formula and preparation method of life cultivation and health preservation food helpful for reducing blood sugar |
CN104547547A (en) * | 2014-12-30 | 2015-04-29 | 兰州古驰生物科技有限公司 | Traditional Chinese medicine preparation used for comprehensively conditioning health of five internal organs |
CN106728868A (en) * | 2016-12-28 | 2017-05-31 | 陕西红顶名医堂药业有限公司 | Chinese medicine composition and preparation method thereof for treating diabetes |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109464598A (en) * | 2018-12-28 | 2019-03-15 | 贵州爱多康生物科技有限公司 | A kind of composition and preparation method thereof containing Acer truncatum leaves for health drink |
CN113785981A (en) * | 2021-10-14 | 2021-12-14 | 潘学群 | Health-preserving medicinal and edible composition and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104435775B (en) | A kind of Traditional Chinese medicinal health-care wine and preparation method thereof | |
CN103039668B (en) | Pueraria breast enlargement tea and preparation method thereof | |
CN103719498B (en) | A kind of Siberian solomonseal rhizome health-care tea improving immunity and preparation method thereof | |
CN104642654A (en) | Health tea for controlling body weight, reducing uric acid and reducing hypertension, hyperglycemia and hyperlipemia | |
CN104351578A (en) | Compound feed for treating chicken internal lesion caused by overexertion and preparation method of compound feed for treating chicken internal lesion caused by overexertion | |
CN104904964A (en) | Folium apocyni veneti health tea capable of decreasing sugar and lipid and preparation method thereof | |
CN107549373A (en) | One kind is used for health care tea capable of reducing blood sugar, preparation method and application | |
CN107519406A (en) | Strengthening spleen, tonifying kidney composition and preparation method thereof | |
CN111358907B (en) | Medicinal and edible traditional Chinese medicine formula granule for treating insomnia and preparation method thereof | |
CN103749819B (en) | Fructus Corni health protection tea of a kind of hypoglycemic and preparation method thereof | |
CN108355088A (en) | A kind of spina date seed medicinal liquor and preparation method thereof improving sleep quality | |
CN108669533A (en) | A kind of meal replacing food and preparation method thereof of conditioning shield stomach | |
CN104474472A (en) | Broadleaf holly leaf buccal tablet capable of reducing high blood pressure, high blood lipid and high blood glucose and production method of buccal tablet | |
CN104206595A (en) | Blood lipid and blood glucose reducing Chinese wolfberry root-bark health care tea and preparation method thereof | |
CN106511705A (en) | Traditional Chinese medicine preparation for treating and regulating blood fat and reducing blood pressure and blood sugar and preparation method | |
CN103461805B (en) | Flour for osteoporosis patients to eat | |
CN107125751B (en) | Tortoise powder, preparation method and application thereof | |
CN104957515A (en) | Steamed buns assisting to lower blood sugar and preparation method thereof | |
CN104825750B (en) | The preparation of a kind of Flos Ginseng processed and preparation method | |
CN103393938B (en) | Traditional Chinese medicine composition for reducing blood sugar | |
CN107212402B (en) | Blood pressure lowering food and preparation method thereof | |
CN105213876A (en) | A kind of medicament for treating insomnia and preparation method thereof | |
CN110101818A (en) | A kind of Chinese medicine for treating diabetes | |
CN104524359B (en) | A kind of Chinese medicine composition, its preparation method and application | |
CN107047868A (en) | A kind of ginger jujube tea and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171229 |