CN107418845A - White stern deer deer-blood wine in the Qilian mountains and preparation method thereof - Google Patents

White stern deer deer-blood wine in the Qilian mountains and preparation method thereof Download PDF

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Publication number
CN107418845A
CN107418845A CN201710262441.2A CN201710262441A CN107418845A CN 107418845 A CN107418845 A CN 107418845A CN 201710262441 A CN201710262441 A CN 201710262441A CN 107418845 A CN107418845 A CN 107418845A
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deer
blood
wine
white
qilian mountains
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杨旭忠
赵晓虎
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QILIANSHAN BIOLOGICAL SCIENCE-TECHNOLOGY DEVELOPMENT Co Ltd GANSU
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QILIANSHAN BIOLOGICAL SCIENCE-TECHNOLOGY DEVELOPMENT Co Ltd GANSU
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention relates to a kind of white stern deer deer-blood wine in Qilian mountains, the wine is made up of the raw material of following weight percentage:The white stern deer deer blood 10 ~ 20% in the Qilian mountains, sealwort 15 ~ 25%, mulberry fruit 15 ~ 25%, intelligence development 15 ~ 25%, spina date seed 20 ~ 30%.Meanwhile the invention also discloses the preparation method of the deer-blood wine.Nutritive value of the present invention is high, save 90% active material and effective ingredient, human body can full dose, balance, rapid absorb, active principle loss amount caused by thoroughly overcoming conventional method is big, complete deactivation, the shortcomings that uptake is low, mouthfeel is uncomfortable, there is the characteristics of high in technological content, added value is high.

Description

White stern deer deer-blood wine in the Qilian mountains and preparation method thereof
Technical field
The present invention relates to biomedicine technical field, more particularly to white stern deer deer-blood wine in the Qilian mountains and preparation method thereof.
Background technology
Deer blood is considered as the top grade of nourishing from ancient times, and China is with a long history applied to health care by deer blood, antler blood, can chase after Trace back to the Song Dynasty.At that time, " lancing is drunk raw "(That is deer live body takes blood to drink)For the road of a kind of nourishing of imperial palace and high official and noble lord, earliest See people Song Zhou Hui's《The miscellaneous knot of clear ripple》.To Ming Dynasty's Li Shizhen《Compendium of Materia Medica》Detailed record then has been done to deer blood medical function: " big qi-restoratives damage, benefiting essence-blood, solution acne poison, medicine poison ".The beneficiating ingredient of deer blood is primarily present in haemocyte, and it has reinforcement Power, lessen fatigue, be nourishing liver and kidney, anti-aging, improving immunity function, increase resistance against diseases and other effects.
Domestic deer-blood wine is most of at present or is exactly that base liquor and deer blood simply mix using traditional production method, Only the producer of very few uses haemocyte enzyme solution, prepares new deer-blood wine, so not only overcomes product appearance Defect, also largely remain the active ingredient in deer blood.
The white stern deer in the Qilian mountains survives in the high-cold steppe of more than 3000 meters of height above sea level, and it, which eats careless class, kind more than 200, wherein 70% is the Chinese herbal medicine of traditional Chinese medical science pharmacopeia record.The special natural conditions in the Qilian mountains, the superior quality of the white stern deer in the Qilian mountains is determined, Had shown that through research, the white stern deer resistance in the Qilian mountains, hypoxia-bearing capability are strong, its byproduct medical value be significantly higher than Plain red deer and Sika deer.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of easily absorption, the white stern deer deer-blood wine in the Qilian mountains in good taste.
Another technical problem to be solved by this invention is to provide the preparation method of the white stern deer deer-blood wine in the Qilian mountains.
To solve the above problems, the white stern deer deer-blood wine in the Qilian mountains of the present invention, it is characterised in that:The wine is by following heavy The raw material of amount percentage is made:The white stern deer deer blood 10 ~ 20% in the Qilian mountains, sealwort 15 ~ 25%, mulberry fruit 15 ~ 25%, intelligence development 15 ~ 25%, acid Jujube kernel 20 ~ 30%.
15 ~ 20% in the white stern deer deer blood dosage in the Qilian mountains be other deer blood.
17 ~ 22% in the sealwort dosage be prepared rhizome of rehmannia.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains as described above, comprises the following steps:
(1) weighed by proportioning;
(2) after the white stern deer deer blood in the Qilian mountains being separated into serum according to a conventional method, erythrocytes of sika deer blood is obtained, and the erythrocytes of sika deer blood uses The sodium carbonate liquor that mass concentration is 5% is diluted to pH=7 ~ 7.3, then adds 1% neutral protein successively by dilution stereometer Enzyme, 0.2% papain, 0.2% trypsase, and digested in 50 ~ 60 DEG C, 65 degree are added after 24 ~ 36 hours Base liquor preserves 12 hours at 0 DEG C, through blending and deer-blood wine is made in filtering;
(3) after mixing sealwort, mulberry fruit, intelligence development, spina date seed, it is 50% to add 7 ~ 10 times of mass concentrations of its quality in the mixture Ethanol solution is extracted, and obtains extract solution, and 20% ~ 40% that ethanol is concentrated into original volume is recovered under reduced pressure in the extract solution, is obtained dense Contracting liquid;
(4) the deer-blood wine is well mixed with the concentrate, produces the white stern deer deer-blood wine in the Qilian mountains.
The step (2) in base liquor refer to fen-flavor type white spirit.
The step (3) in extraction conditions refer to that temperature is 70 DEG C ~ 100 DEG C, extraction time is 2 ~ 3 times, 2 ~ 3h every time.
The step (3) in concentration condition refer to 80 DEG C ~ 90 DEG C of thickening temperature, vacuum 0.08MPa ~ 0.09MPa.
The present invention has advantages below compared with prior art:
1st, the white stern deer deer blood nutritive value in the Qilian mountains is higher than general deer blood in the present invention, and the formula white stern deer deer blood in the Qilian mountains is monarch, Help the work(of qi-restoratives and blood;Minister is invigorated the spleen and benefited qi with sealwort nourshing kidney moistening lung;Assistant is strong with mulberry fruit liver-kidney tonifying, ease constipation of promoting the production of body fluid, help Work(;Make with intelligence development, spina date seed, tonifying liver, calming heart, arrest sweating, promote the production of body fluid, benefiting qi for tranquillization.Monarch qi-restoratives and blood, promotes the production of body fluid to 5 Yin-nourishing, clearing away the lungheat and moisturizing, tonifying five zang organs, simultaneous application of cooling and tonifying therapy is adjusted to control.
2nd, products obtained therefrom of the present invention is the white stern deer deer-blood wine in the Qilian mountains, and its external appearance characteristic is brown yellow transparent liquid, it is allowed to There is a small amount of precipitation, there is the compound fragrance that fen-flavor type white spirit is main body, slightly sweetness and bitterness taste and the deer smell of blood.Its key technical indexes For:Alcoholic strength 28.0 ± 1.0%(V/V), 0.30~1.0g/ of total acid L, total ester >=1.5g/L, ethyl hexanoate >=1.0g/L, Iron >=4mg/L, solid content >=2%.
3rd, present invention centrifugation, haemocyte enzymolysis, extracts active ingredients, the technique such as blend, improve the battalion of product Support value, save 90% active material and effective ingredient in product, human body can full dose, balance, rapid absorption, thoroughly overcome Active principle loss amount caused by conventional method is big, complete deactivation, the shortcomings that uptake is low, mouthfeel is uncomfortable, contain with science and technology The characteristics of amount is high, added value is high.
Embodiment
The white stern deer deer-blood wine in the Qilian mountains of embodiment 1, the wine is by following weight percentage(kg/kg)Raw material be made:Qi The white stern deer deer blood 10% in the Lianshan Mountain, sealwort 25%, mulberry fruit 25%, intelligence development 15%, spina date seed 25%.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains, comprises the following steps:
(1) weighed by proportioning.
(2) the white stern deer deer blood in the Qilian mountains is centrifuged 20 minutes with centrifuge with 3000 rpm rotating speed according to a conventional method, removed After serum, erythrocytes of sika deer blood is obtained, the erythrocytes of sika deer blood uses mass concentration to be diluted to pH=7 ~ 7.3 for 5% sodium carbonate liquor, Then 1% neutral proteinase, 0.2% papain, 0.2% trypsase is added successively by dilution stereometer, and in 50 ~ 60 DEG C are digested, and 65 degree of base liquor is added after 24 ~ 36 hours and is preserved 12 hours at 0 DEG C, through blending and deer is made in filtering Blood wine.
Wherein:Base liquor refers to fen-flavor type white spirit.
(3) after mixing sealwort, mulberry fruit, intelligence development, spina date seed, adding 7 ~ 10 times of mass concentrations of its quality in the mixture is 50% ethanol solution, extracted in 70 DEG C ~ 100 DEG C 2 ~ 3 times, 2 ~ 3h, merging every time obtains extract solution, and the extract solution is in concentration temperature 80 DEG C ~ 90 DEG C of degree, under conditions of vacuum 0.08MPa ~ 0.09MPa through be recovered under reduced pressure ethanol be concentrated into original volume 20% ~ 40%, obtain concentrate.
(4) deer-blood wine is well mixed with concentrate, produces the white stern deer deer-blood wine in the Qilian mountains.
The white stern deer deer-blood wine in the Qilian mountains of embodiment 2, the wine is by following weight percentage(kg/kg)Raw material be made:Qi The white stern deer deer blood 20% in the Lianshan Mountain, sealwort 15%, mulberry fruit 15%, intelligence development 20%, spina date seed 30%.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains is the same as embodiment 1.
The white stern deer deer-blood wine in the Qilian mountains of embodiment 3, the wine is by following weight percentage(kg/kg)Raw material be made:Qi The white stern deer deer blood 15% in the Lianshan Mountain, sealwort 20%, mulberry fruit 20%, intelligence development 20%, spina date seed 25%.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains is the same as embodiment 1.
The white stern deer deer-blood wine in the Qilian mountains of embodiment 4, the wine is by following weight percentage(kg/kg)Raw material be made:Qi The white stern deer deer blood 19% in the Lianshan Mountain, sealwort 18%, mulberry fruit 18%, intelligence development 25%, spina date seed 20%.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains is the same as embodiment 1.
The white stern deer deer-blood wine in the Qilian mountains of embodiment 5, the wine is by following weight percentage(kg/kg)Raw material be made:Qi The white stern deer deer blood 20% in the Lianshan Mountain, sealwort 15%, mulberry fruit 15%, intelligence development 20%, spina date seed 30%.
Wherein:15 ~ 20% in the white stern deer deer blood dosage in the Qilian mountains be other deer blood.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains is the same as embodiment 1.
The white stern deer deer-blood wine in the Qilian mountains of embodiment 6, the wine is by following weight percentage(kg/kg)Raw material be made:Qi The white stern deer deer blood 10% in the Lianshan Mountain, sealwort 25%, mulberry fruit 25%, intelligence development 15%, spina date seed 25%.
Wherein:17 ~ 22% in sealwort dosage be prepared rhizome of rehmannia.
The preparation method of the white stern deer deer-blood wine in the Qilian mountains is the same as embodiment 1.

Claims (7)

1. the white stern deer deer-blood wine in the Qilian mountains, it is characterised in that:The wine is made up of the raw material of following weight percentage:The white stern in the Qilian mountains Deer deer blood 10 ~ 20%, sealwort 15 ~ 25%, mulberry fruit 15 ~ 25%, intelligence development 15 ~ 25%, spina date seed 20 ~ 30%.
2. the white stern deer deer-blood wine in the Qilian mountains as claimed in claim 1, it is characterised in that:The white stern deer deer blood dosage in the Qilian mountains In 15 ~ 20% be other deer blood.
3. the white stern deer deer-blood wine in the Qilian mountains as claimed in claim 1, it is characterised in that:17 ~ 22% in the sealwort dosage are Prepared rhizome of rehmannia.
4. the preparation method of the white stern deer deer-blood wine in the Qilian mountains as claimed in claim 1, comprises the following steps:
(1) weighed by proportioning;
(2) after the white stern deer deer blood in the Qilian mountains being separated into serum according to a conventional method, erythrocytes of sika deer blood is obtained, and the erythrocytes of sika deer blood uses The sodium carbonate liquor that mass concentration is 5% is diluted to pH=7 ~ 7.3, then adds 1% neutral protein successively by dilution stereometer Enzyme, 0.2% papain, 0.2% trypsase, and digested in 50 ~ 60 DEG C, 65 degree are added after 24 ~ 36 hours Base liquor preserves 12 hours at 0 DEG C, through blending and deer-blood wine is made in filtering;
(3) after mixing sealwort, mulberry fruit, intelligence development, spina date seed, it is 50% to add 7 ~ 10 times of mass concentrations of its quality in the mixture Ethanol solution is extracted, and obtains extract solution, and 20% ~ 40% that ethanol is concentrated into original volume is recovered under reduced pressure in the extract solution, is obtained dense Contracting liquid;
(4) the deer-blood wine is well mixed with the concentrate, produces the white stern deer deer-blood wine in the Qilian mountains.
5. the preparation method of the white stern deer deer-blood wine in the Qilian mountains as claimed in claim 4, it is characterised in that:The step (2) in Base liquor refers to fen-flavor type white spirit.
6. the preparation method of the white stern deer deer-blood wine in the Qilian mountains as claimed in claim 4, it is characterised in that:The step (3) in Extraction conditions refer to that temperature is 70 DEG C ~ 100 DEG C, and extraction time is 2 ~ 3 times, every time 2 ~ 3h.
7. the preparation method of the white stern deer deer-blood wine in the Qilian mountains as claimed in claim 4, it is characterised in that:The step (3) in Concentration condition refers to 80 DEG C ~ 90 DEG C of thickening temperature, vacuum 0.08MPa ~ 0.09MPa.
CN201710262441.2A 2017-04-20 2017-04-20 White stern deer deer-blood wine in the Qilian mountains and preparation method thereof Pending CN107418845A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107952021A (en) * 2017-12-12 2018-04-24 齐华 A kind of assembled alcoholic drinks and preparation method thereof
CN110157579A (en) * 2019-06-06 2019-08-23 甘肃祁连山生物科技开发有限责任公司 A kind of compound deer-blood wine and preparation method thereof for Hypertensive Population
CN114410419A (en) * 2022-01-18 2022-04-29 西藏金哈达寿康实业有限公司 Highland barley medicinal liquor and preparation method thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1099620A (en) * 1993-09-03 1995-03-08 吉林省商检应用技术研究所 Biochemical preparing method for deer blood wine
CN1253786A (en) * 1998-11-16 2000-05-24 宋胜利 Fresh deer's blood health-care medicated wine and its preparation method
CN1542116A (en) * 2003-11-06 2004-11-03 上海鼎乐生物科技有限公司 Process for producing deer-blood wine
CN1635087A (en) * 2004-10-13 2005-07-06 李富祥 Dispense of nourishing medicated wine
CN101352510A (en) * 2007-07-26 2009-01-28 江苏康缘药业股份有限公司 Deer blood wine for improving immunity of body and preparation method thereof
CN103146559A (en) * 2013-03-06 2013-06-12 郑镁钢 Nutritive health-care wine and preparation method thereof
CN104666899A (en) * 2015-03-31 2015-06-03 苏州市天灵中药饮片有限公司 Traditional Chinese medicinal liquor for tonifying kidneys and beautifying face and preparation method of traditional Chinese medicine liquor
CN106214989A (en) * 2016-09-06 2016-12-14 贵州科博生物科技有限公司 A kind of defying age, the deer's blood health-care medicated wine improving memory and preparation method thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1099620A (en) * 1993-09-03 1995-03-08 吉林省商检应用技术研究所 Biochemical preparing method for deer blood wine
CN1253786A (en) * 1998-11-16 2000-05-24 宋胜利 Fresh deer's blood health-care medicated wine and its preparation method
CN1542116A (en) * 2003-11-06 2004-11-03 上海鼎乐生物科技有限公司 Process for producing deer-blood wine
CN1635087A (en) * 2004-10-13 2005-07-06 李富祥 Dispense of nourishing medicated wine
CN101352510A (en) * 2007-07-26 2009-01-28 江苏康缘药业股份有限公司 Deer blood wine for improving immunity of body and preparation method thereof
CN103146559A (en) * 2013-03-06 2013-06-12 郑镁钢 Nutritive health-care wine and preparation method thereof
CN104666899A (en) * 2015-03-31 2015-06-03 苏州市天灵中药饮片有限公司 Traditional Chinese medicinal liquor for tonifying kidneys and beautifying face and preparation method of traditional Chinese medicine liquor
CN106214989A (en) * 2016-09-06 2016-12-14 贵州科博生物科技有限公司 A kind of defying age, the deer's blood health-care medicated wine improving memory and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107952021A (en) * 2017-12-12 2018-04-24 齐华 A kind of assembled alcoholic drinks and preparation method thereof
CN110157579A (en) * 2019-06-06 2019-08-23 甘肃祁连山生物科技开发有限责任公司 A kind of compound deer-blood wine and preparation method thereof for Hypertensive Population
CN114410419A (en) * 2022-01-18 2022-04-29 西藏金哈达寿康实业有限公司 Highland barley medicinal liquor and preparation method thereof

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