A kind of health food comprising xanthans
Technical field
The invention belongs to food processing technology field, relate to a kind of health food comprising xanthans particularly.
Background technology
Xanthans is also known as yellow glue, xanthan gum, Xanthan Gum, it is a kind of monospore polysaccharide of generation of being fermented by false xanthomonas, be primary raw material by cabbage black rot xanthomonas campestris with carbohydrate, through aerobic fermentation biotechnology, cut off 1,6-glycosidic bond, after opening side chain, by the outer heteroglycan of the acid born of the same parents of the one of Isosorbide-5-Nitrae-be bonded to straight chain composition.Nineteen fifty-two is separated by the northern research institute in Pi Ao Lille, United States Department of Agriculture Illinois the Xanthomonas campestris pv. campestris obtained, and makes cabbage extract be converted into the outer heteroglycan of water miscible acid born of the same parents and obtain.
Xanthans is the thickener of food industry middle ideal, suspending agent, emulsifying agent and forming agent, Performance Ratio gelatin, the CMC(carboxymethyl cellulose of xanthans under some harsh conditions), the foodstuffs additive such as marine alga has more superiority.To be applied in dairy produce (as cheese, fruit and milk drink, ice cream, Yoghourt etc.) can modification quality, increase stability, be easy to fragrance release, the effect such as delicate mouthfeel is salubrious.For fruit drink, have good compatibility with other additives, energy Effective Suspension pulp and release local flavor, keep uniform liquid not stratified.Add in beer, produce bubble excellent.In frozen food, repeatedly after freeze-thaw, still there is good stability energy and water retention property, reduce freezing crystalline substance, make food mouthfeel smooth.
Osteoporosis is that bone density because many reasons causes and bone mass decline, and bone micro-structure destroys, and causes bone fragility to increase, thus the general osteopathy of fracturing easily occurs.Osteoporosis is divided into primary and the large class of Secondary cases two.Primary osteoporosis is divided into again PMO (I type), senile osteoporosis (II type) and idiopathic osteoporosis (comprising juvenile) three kinds.PMO generally to occur in after postmenopausal women in 5-10; Senile osteoporosis refers generally to the osteoporosis that old man occurs for 70 years old afterwards; And idiopathic osteoporosis mainly occurs in teenager, the cause of disease is still not clear; Wherein, occurring is senile osteoporosis the most frequently.Osteoporosis is the important symbol of aging population society.The therapeutic modality of current routine is generally that drug therapy adds dietetic regulation, and conventional medicine is anti-bone information medicine and promoting bone growing medicine, and diet mainly eats some and is rich in calcareous food.Prolonged administration of drugs easily causes kidney stone, higher urinary calcium and calcium intoxication etc., brings white elephant also can to liver kidney, also bring larger financial burden to patient simultaneously.How effectively can treat osteoporosis only by dietotherapy is prior art technical barrier urgently to be resolved hurrily.
Summary of the invention
In order to solve the technical problem of above-mentioned existence, the invention provides a kind of health food comprising xanthans, this food can make prevention and therapy osteoporosis effectively, improves bone density and bone mass, can reduce and take medicine or without the need to taking medicine, avoid the toxic and side effect that medicine brings.
For achieving the above object, the technical solution used in the present invention is as follows:
Comprise a health food for xanthans, it is prepared as follows and obtains: 1) prepare compound A; 2) compound B is prepared; 3) compound C is prepared; 4) compound D is prepared; 5) xanthans compound additive is prepared; 6) health food is prepared.
Particularly, it is prepared as follows and obtains:
1) compound A is prepared: the red sage root, matrimony vine and the Chinese yam weight ratio according to 2:1:1 mixed, add the soak by water 1 hour of 10 times of weight, collecting by filtration filtrate, the pH adjusting filtrate with the hydrochloric acid solution of 1mol/L is 6.5, then filtrate is condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, be ground into powder and get final product;
2) prepare compound B: the rhizome of davallia and pseudo-ginseng are mixed according to the weight ratio of 1:1, pulverize, add water boil 20min, collecting by filtration filtrate, be then condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, be ground into powder, obtain final product; The mass ratio of described pseudo-ginseng and water is 1:5;
3) prepare compound C: dandelion and Fructus Hordei Germinatus are mixed according to the weight ratio of 3:1, then adding volume fraction is soak 30 minutes in the ethanol of 70%, and be not as the criterion, decompression rotary evaporation removes ethanol; Add the alcohol immersion 30min that volume fraction is 85% again, be not as the criterion, then 1000 turns/min collected by centrifugation supernatant, supernatant concentration become density to be the medicinal extract of 1.2g/ml, after 80 DEG C of dryings, be ground into powder, obtain final product;
4) prepare compound D: oat and soybean are mixed according to the weight ratio of 3:1, be then ground into powder, cross 300 mesh sieves and get final product;
5) xanthans compound additive is prepared: xanthans, calcium lactate and the sodium alginate weight ratio according to 3:2:1 mixed, stir, to obtain final product;
6) prepare health food: put in milk by compound A, compound B, compound C, compound D and xanthans compound additive, mix, be then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18 ~ 20Mpa; Finally the mixed material after homogeneous is placed in 95 DEG C of sterilizations 120 seconds, package encapsulation and get final product;
The weight ratio of described compound A, compound B, compound C, compound D, xanthans compound additive and milk is 5-9:7-10:9-15:12-21:1-2:500-1000.
The beneficial effect of health food of the present invention mainly comprises as follows: health-care food preparation technology of the present invention is unique, extracts to greatest extent and obtains active ingredient, decrease wastage of material, saved cost; Food of the present invention eats to osteoporosis patient, effectively can treat osteoporosis, improve bone density and bone mass; The present invention adds the xanthans compound additive in allowed band, possesses thickening suspension effect, improves mouthfeel, supplements calcareous; The present invention selects multiple medicinal herb components, reasonable compatibility, adds in dairy produce dexterously, the health therapy function of the edible function of dairy produce and medicinal material is combined together; Avoid the side effect that patient's Long-term taking medicine brings, and alleviate the financial burden of patient; Preparation method's simple possible of health food of the present invention, can large-scale industrial production.
Detailed description of the invention
According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, concrete material proportion, process conditions and result thereof described by embodiment only for illustration of the present invention, and should can not limit the present invention described in detail in claims yet.
Embodiment 1
Comprise a health food for xanthans, it is prepared as follows and obtains:
1) compound A is prepared: the red sage root, matrimony vine and the Chinese yam weight ratio according to 2:1:1 mixed, add the soak by water 1 hour of 10 times of weight, collecting by filtration filtrate, the pH adjusting filtrate with the hydrochloric acid solution of 1mol/L is 6.5, then filtrate is condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, be ground into powder and get final product;
2) prepare compound B: the rhizome of davallia and pseudo-ginseng are mixed according to the weight ratio of 1:1, pulverize, add water boil 20min, collecting by filtration filtrate, be then condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, be ground into powder, obtain final product; The mass ratio of described pseudo-ginseng and water is 1:5;
3) prepare compound C: dandelion and Fructus Hordei Germinatus are mixed according to the weight ratio of 3:1, then adding volume fraction is soak 30 minutes in the ethanol of 70%, and be not as the criterion, decompression rotary evaporation removes ethanol; Add the alcohol immersion 30min that volume fraction is 85% again, be not as the criterion, then 1000 turns/min collected by centrifugation supernatant, supernatant concentration become density to be the medicinal extract of 1.2g/ml, after 80 DEG C of dryings, be ground into powder, obtain final product;
4) prepare compound D: oat and soybean are mixed according to the weight ratio of 3:1, be then ground into powder, cross 300 mesh sieves and get final product;
5) xanthans compound additive is prepared: xanthans, calcium lactate and the sodium alginate weight ratio according to 3:2:1 mixed, stir, to obtain final product;
6) prepare health food: put in milk by compound A, compound B, compound C, compound D and xanthans compound additive, mix, be then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18 ~ 20Mpa; Finally the mixed material after homogeneous is placed in 95 DEG C of sterilizations 120 seconds, package encapsulation and get final product;
The weight ratio of described compound A, compound B, compound C, compound D, xanthans compound additive and milk is 5:7:9:12:1:500.
Edible way: twice daily, each 200-300ml.
Embodiment 2
Comprise a health food for xanthans, it is prepared as follows and obtains:
1) compound A is prepared: the red sage root, matrimony vine and the Chinese yam weight ratio according to 2:1:1 mixed, add the soak by water 1 hour of 10 times of weight, collecting by filtration filtrate, the pH adjusting filtrate with the hydrochloric acid solution of 1mol/L is 6.5, then filtrate is condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, be ground into powder and get final product;
2) prepare compound B: the rhizome of davallia and pseudo-ginseng are mixed according to the weight ratio of 1:1, then with high-speed tissue mashing machine's making beating, add water boil 20min, collecting by filtration filtrate, is then condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, be ground into powder, obtain final product; The mass ratio of described pseudo-ginseng and water is 1:5;
3) prepare compound C: dandelion and Fructus Hordei Germinatus are mixed according to the weight ratio of 3:1, then adding volume fraction is soak 30 minutes in the ethanol of 70%, and be not as the criterion, decompression rotary evaporation removes ethanol; Add the alcohol immersion 30min that volume fraction is 85% again, be not as the criterion, then 1000 turns/min collected by centrifugation supernatant, supernatant concentration become density to be the medicinal extract of 1.2g/ml, after 80 DEG C of dryings, be ground into powder, obtain final product;
4) prepare compound D: oat and soybean are mixed according to the weight ratio of 3:1, be then ground into powder, cross 300 mesh sieves and get final product;
5) xanthans compound additive is prepared: xanthans, calcium lactate and the sodium alginate weight ratio according to 3:2:1 mixed, stir, to obtain final product;
6) prepare health food: put in milk by compound A, compound B, compound C, compound D and xanthans compound additive, mix, be then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18 ~ 20Mpa; Finally the mixed material after homogeneous is placed in 95 DEG C of sterilizations 120 seconds, package encapsulation and get final product;
The weight ratio of described compound A, compound B, compound C, compound D, xanthans compound additive and milk is 9:10:15:21:2:1000.
Edible way: twice daily, each 200-300ml.
Embodiment 3
Pharmacological evaluation
Health food prepared by edible the present invention is on the impact of SD rat blood serum calcium and writhing response;
Select SD rat, body weight (250 ± 10) g, is provided by Shandong University's experimental animal center by 30.Be divided into 3 groups at random, blank group 10, experimental group 10, negative control group.Blank group gives physiological saline, and experimental group of the present invention and negative control group all give dexamethasone 1mg/kg, injection in every three days once, intramuscular injection, meanwhile, associating vitamin A acid gavage, every day consumption 70mg/kg, totally three weeks.
Feeding methods: during modeling, blank group and negative control group eat normal diet, experimental group of the present invention eats the food of the embodiment of the present invention 1, every day 50ml.After 20 days, detect writhing number of times, then afterbody gets blood, and centrifuging and taking serum, detects serum calcium levels with automatic clinical chemistry analyzer.See table 1
Table 1
Classification |
Serum calcium levels (mmol/L) |
Writhing number of times in a quarter of an hour |
Blank group |
1.81±0.32 |
Nothing |
Experimental group of the present invention |
1.97±0.29 |
10±3 |
Negative control group |
3.64±0.53 |
43±9 |
Conclusion: experimental group serum calcium levels of the present invention obviously reduces, the calcium loss in visible sclerotin is less, and writhing number of times greatly reduces, and possesses good analgesic activity as seen.
Embodiment 4
Clinical model case
Zhu, man, 56 years old; Pain in the back pain 20 years, recurrent exerbation, nearly half a year increases the weight of.The manual labor of patient's long campaigns, for a long time after the sitting of station, can not normal waking activity when standing, be in a bad way outbreak every year repeatedly.Show through X-ray: lumbar curvature straightens, hyperosteogeny spur is " beak shape ", narrowing of intervertebral space.Be diagnosed as: senile osteoporosis.Adhere to every day eating the health food into embodiment 1 preparation, every day, 500ml, ate at twice, and edible after one month, symptom alleviates, and continue edible half a year, various transference cure, bone density is normally close.
Above-mentioned employing specific embodiment is to invention has been detailed description; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.