CN107412841A - A kind of production method of medical tea oil dressing - Google Patents
A kind of production method of medical tea oil dressing Download PDFInfo
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- CN107412841A CN107412841A CN201710675194.9A CN201710675194A CN107412841A CN 107412841 A CN107412841 A CN 107412841A CN 201710675194 A CN201710675194 A CN 201710675194A CN 107412841 A CN107412841 A CN 107412841A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/30—Rubbers or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
Abstract
The invention discloses a kind of production method of medical tea oil dressing, this method passes through step A E, by under certain condition by certain mass than injection add-on type liquid silicon rubber component A and B component first be each well mixed with camellia oil, it is well mixed mutually under certain condition again and inputs slobbering machine and carries out salivation film forming, and solidify under the temperature and time of specific selection, then obtain medical tea oil dressing through the step such as cutting and winding.This method is simple and efficient, production efficiency is high, simultaneously, the medical tea oil dressing that this method is produced has the effect of excellent anti-inflammation and hemostasis, and the environment that a moistening can be provided to wound promotes its healing, and adhesion wound, the pain of patient when reducing replacing, the patient for being especially suitable for burn and scald use in use.
Description
Technical field
The invention belongs to medical macromolecular materials preparation field, and in particular to a kind of production method of medical tea oil dressing.
Background technology
Dressing is to wrap up the articles for use of wound, to cover the medical material of sore, wound or other infringements.To wound healing
Research shows, using the purpose not just flap coverage of dressing, dressing should also have the function that to promote wound healing, therefore with
The physiopathologic further investigation to wound, understanding of the people to wound is also more and more deep, from
And it result in updating and developing for Medical wounded surface dressing.In addition, theoretical according to " wet wound healing ", wound is in moistening
Healed faster in environment, so the reasonable selection of surface of a wound externally applied drug is most important.Now, new surface of a wound nursing dressing phase
For early stage, revolutionary change is had occurred that, the medical dressing of existing a variety of different performances is available for clinical shield now
The choice of members is managed, and deepening constantly with research, the various dressing with specific function are just continually developed, and meet people
For the use in the case of various.
Dressing now is roughly divided into two classes, i.e. traditional dressing and modern dressing, and traditional dressing is normal gauze, and modern
Dressing is divided into the dressing of synthetic fibers class, more poly film class dressing and foaming polymer class dressing etc. again.Normal gauze purposes compares biography
System, it is mainly used to isolate wound and absorbs wound surface diffusate, but because its permeability is too high, is easily dehydrated the surface of a wound, and
External environment microorganism is easily by the chance of cross-infection is higher, and the surface of a wound of adhering, and property machinery again can be caused during replacing
Property damage, meanwhile, normal gauze needs frequently to change frequent, can bring pain to patient.And the dressing of synthetic fibers class is then effect
What the functional development of imitative dry gauze and oily yarn came out, effect normal gauze is the same, but there is also it is corresponding the problem of.More poly film classes
Dressing is a kind of more advanced dressing, has the gases such as oxygen, vapor can be freely penetrating, and graininess foreign matter in environment
The intransitable feature of such as dust and microorganism, but its there is also it is certain the shortcomings that, that is, absorb sepage ability, cost
Height, and surface of a wound surrounding skin impregnator can be big, therefore this kind of dressing is mainly applied to postoperative and oozes out few surface of a wound, or
Complementary dressing of the person as other dressing, is of limited application.The main component of hydrocolloid class dressing is a kind of hydrophilic ability
Very strong hydrocolloid-sodium carboxymethylcellulose particle (CMC), sodium carboxymethylcellulose particle (CMC) and hypoallergenic are medical
Viscose glue, dressing main body being collectively formed plus elastomer, plasticizer etc., its surface, which is one layer, has semipermeable poly membrane structure,
After this dressing contacts with wound fluid, exudate can be absorbed, and forms a kind of gel, avoids dressing from being adhered with the surface of a wound, table
The semi-transparent membrane structure in face can allow oxygen and vapor to swap, but with external boundry particle foreign matter such as dust and carefully
Bacterium has barrier, meanwhile, he there is also this it is certain the problem of, i.e., absorbability is not very strong, therefore for high exudative wound
Face, other auxiliary dressing are often needed to use to strengthen absorbent properties, and few patients there may be to composition allergy, so its
Application is still than relatively limited.
Camellia oil obtains from Theaceae tea oil tree seed, is one of most ancient woody edible vegetable oil in China,
China is that plant of theaceae is distributed most wide country in the world, is tea oil production base maximum in the world, in addition only has
The state-owned minimal amount of distribution such as Southeast Asia, Japan.Camellia oil is among the people also to sting it for mosquito in addition to as edible oil
Sting, children's crissum erythema, burn and scald etc., and it is evident in efficacy.Be the discovery that by research because camellia oil to contain abundant tea more
Phenol, and Tea Polyphenols has the function that excellent antibacterial and promotion wound healing, so camellia oil is widely present in processing wound
In folk prescription, and for the significant effect of burn and scald.
Because medical grade silicon rubber has higher temperature tolerance, resistance to oxidation, hydrophobicity, flexibility, permeability, ageing-resistant transparent
Spend height, physiological inertia, good, nontoxic, tasteless, not carcinogenic etc. a series of excellent with tissue and blood adhesion, biocompatibility
Good characteristic, therefore be widely used in preparing artificial peritonaeum, artificial knuckle, soft tissue expander, artificial skin and each
The medical products such as kind dressing.Silicon rubber for producing corresponding dressing because injection add-on type liquid silicon rubber have it is excellent
Transparency, excellent drawing stretch intensity and tearing toughness, excellent resilience, excellent heat endurance and weatherability, yellowing-resistant,
The characteristics such as heat-proof aging, so injection add-on type liquid silicon rubber is one of most suitable raw material, inject add-on type liquid silicon rubber
Glue is that poly- containing vinyl has siloxanes to make base polymer, and poly- containing Si -- H bond has siloxanes to make crosslinking agent, in platinum catalysis
In the presence of agent, one kind of cross-linking vulcanization has silicon materials under room temperature or heating.Injection add-on type liquid silicon rubber is a kind of suitable
Together in the high anti-tear liquid silicon rubber material of two-component platinum catalysis high transparency of injection molding technique, add-on type liquid silicon rubber is injected
Glue is generally divided into component A and B component, wherein, the composition of component A is vinyl silicone oil, methyl-silicone oil, white carbon and platinum catalysis
Agent etc., the composition of B component are vinyl silicone oil, methyl-silicone oil, containing hydrogen silicone oil and silica etc., meanwhile, pass through and adjust formula
And the methods of with addition reaction inhibitor control curingprocess rate, the product for adapting to multiple use can be made.
For wound caused by burn and scald, breakage will not be typically produced immediately, but after post-processing and using auxiliary material, because
To be easy to cause skin to fester on generation mechanical contact, the condition of the injury is aggravated, scar is produced after follow-up wound healing, together
When, the wound of burn and scald can typically ooze out tissue fluid more than comparison, it is necessary to which dressing absorbs to it in time, and prevents its adhesion again
Wound, the pain of patient when changing is reduced, therefore, the dressing being applicable for burn and scald also requires higher, and existing dressing portion
Point function can reach related request, but aggreggate utility also has gap, therefore applying for burn and scald wound from perfect condition
Material also needs constantly to be improved, to adapt to the burn and scald accident to take place frequently now.
The content of the invention
(1) technical problems to be solved
In view of the shortcomings of the prior art, the technical problem to be solved in the present invention is to provide a kind of production of medical tea oil dressing
Method, this method is simple and efficient, and production efficiency is high, meanwhile, the medical tea oil dressing that this method is produced has excellent antibacterial
The effect of anti-inflammatory and hemostasis, and the environment that a moistening can be provided to wound promotes its healing, and do not glue in use
Even wound, the pain of patient when changing is reduced, the patient for being especially suitable for burn and scald uses.
(2) technical scheme
In order to solve the above-mentioned technical problem, the invention provides the production method of such a medical tea oil dressing, specifically
Comprise the following steps：
A. according to mass percent meter, that takes 75-95% injects add-on type liquid silicon rubber component A and 5-25% mountain
Tea oil, it is mixed evenly at normal temperatures, mixing speed 1500-3000r/min, obtains mixture one；
B. according to mass percent meter, that takes 75-95% injects add-on type liquid silicon rubber B component and 5-25% mountain
Tea oil, it is mixed evenly at normal temperatures, mixing speed 1500-3000r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three is inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification temperature 70-90
DEG C, hardening time is 35-45 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
Preferably, in step, according to mass percent meter, 85% injection add-on type liquid silicon rubber component A is taken
Camellia oil with 15%, is mixed evenly at normal temperatures, mixing speed 2200r/min, obtains mixture one；In step B
In, according to mass percent meter, 85% injection add-on type liquid silicon rubber B component and 15% camellia oil are taken, in normal temperature
Under be mixed evenly, mixing speed 2200r/min, obtain mixture two；In step C, according to mass percent meter, take
With the mixture two of 50% mixture one and 50%, it is mixed evenly, mixing speed 500r/min, obtains at normal temperatures
Mixture three.
Preferably, in step D, solidification is carried out using staged, solidifies the first stage, and solidification temperature is 70 DEG C, solidification
Time is 6 minutes；Solidify second stage, solidification temperature is 76 DEG C, and hardening time is 8 minutes；Solidify phase III, solidification temperature
For 83 DEG C, hardening time is 10 minutes；Solidify fourth stage, solidification temperature is 90 DEG C, and hardening time is 16 minutes.
(3) beneficial effect
The present invention compared with prior art, overcomes the deficiencies in the prior art, first, passes through certain matter under certain condition
The injection add-on type liquid silicon rubber component A and B component for measuring ratio are first each well mixed with camellia oil, and mutual under certain condition
Mix uniformly and input slobbering machine and carry out salivation film forming, and solidify under the temperature and time of specific selection, then through undue
The step such as cut and wind and obtain medical tea oil dressing finished product, it is possible thereby to become apparent from that this method is simple and efficient, cost
Time, short production efficiency was high；Secondly, camellia oil is added in the present invention, and by stirring first by camellia oil respectively with injecting addition
Type liquid silastic component A and B component are well mixed, then both are well mixed and salivated, and camellia oil is participated in silicon rubber
In the formation of film, camellia oil is evenly distributed in silicon rubber film, and makes camellia oil by solidifying, cutting and wind etc.
Fusion completely is in medical tea oil dressing finished product, so as to make the medical tea oil dressing produced using the correlation properties of camellia oil
There is the effect of excellent anti-inflammation and hemostasis；Again, medical artificial skin is eliminated without using organic solvent in process of production
The possibility of skin finished product residual organic solvent, solve organic solvent and volatilize in process of production and endangered with waste liquid to caused by environment
Evil, so that more safety and environmental protection, to human body and environment non-hazardous, also, the nontoxic no sensitization of artificial skin so produced,
With the skin good biocompatibility of human body in itself；Finally, just because of camellia oil is added separately to inject add-on type liquid silicon rubber
Glue component A and B component, and both are well mixed and salivated, therefore, salivate and solidify by this species specific blending constituent
Caused medical tea oil dressing has preferable compactness, and not and resistance bacterium performance is especially excellent, moreover it is possible to wet to wound offer one
The environment of profit promotes its healing, meanwhile, dressing of the invention can realize with wound adhesion, when significantly reducing changing medicine for patient
Pain.In general, the present invention is simple and efficient, and production efficiency is high, meanwhile, the medical tea oil dressing that this method is produced has excellent
The effect of good anti-inflammation and hemostasis, and the environment that a moistening can be provided to wound promotes its healing, and make
With middle adhesion wound, the pain of patient when changing is reduced, is especially suitable for patient's use of burn and scald.
Further, in step A, B and C, it is specific selection injection add-on type liquid silicon rubber component A and B groups and
The combined amount of camellia oil, and select to be mixed under optimum temperature and stirring condition uniformly, it can so improve medical tea
The uniformity of oily dressing finished product, so as to optimize the quality for producing medical tea oil dressing finished product, lift its anti-inflammation and hemostasis
The effect of, provide an optimum environment to wound.
Further, in step D, using stepwise being solidified, join in combination with optimum temperature and time
Number, these parameters are all the optimized parameters by largely testing and attempting just to draw, have high practicality, by optimal
The temperature and time condition of change is solidified, and is dramatically improved the molding effect of medical tea oil dressing finished product, is made it more frivolous, more
It is easy to the processing such as follow-up shearing, is more convenient for using as burn and scald dressing in the case of various, meanwhile, lift further lifting
The effect of material anti-inflammation itself and hemostasis, and it is not easy adhesion wound, reduce the pain of patient when changing.
Embodiment
, below will be right to be easy to understand the technical means, the inventive features, the objects and the advantages of the present invention
Technical scheme in the embodiment of the present invention carries out clear, complete description, so that the present invention is expanded on further, it is clear that described
Embodiment is only the part of the embodiment of the present invention, rather than whole embodiments.
Embodiment 1
A kind of production method of medical tea oil dressing, specifically comprises the following steps：
A. according to mass percent meter, 75% injection add-on type liquid silicon rubber component A and 25% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 1500r/min, obtains mixture one；
B. according to mass percent meter, 75% injection add-on type liquid silicon rubber B component and 25% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 1500r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three being inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification temperature is 70 DEG C,
Hardening time is 45 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
By said process, the sample 1 of medical tea oil dressing finished product is obtained.
Embodiment 2
A kind of production method of medical tea oil dressing, specifically comprises the following steps：
A. according to mass percent meter, 85% injection add-on type liquid silicon rubber component A and 15% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 2200r/min, obtains mixture one；
B. according to mass percent meter, 85% injection add-on type liquid silicon rubber B component and 15% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 2200r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three being inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification temperature is 80 DEG C,
Hardening time is 30 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
By said process, the sample 2 of medical tea oil dressing finished product is obtained.
Embodiment 3
A kind of production method of medical tea oil dressing, specifically comprises the following steps：
A. according to mass percent meter, 95% injection add-on type liquid silicon rubber component A and 5% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 3000r/min, obtains mixture one；
B. according to mass percent meter, 95% injection add-on type liquid silicon rubber B component and 5% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 3000r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three being inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification temperature is 90 DEG C,
Hardening time is 35 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
By said process, the sample 3 of medical tea oil dressing finished product is obtained.
Embodiment 4
A kind of production method of medical tea oil dressing, specifically comprises the following steps：
A. according to mass percent meter, 75% injection add-on type liquid silicon rubber component A and 25% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 1500r/min, obtains mixture one；
B. according to mass percent meter, 75% injection add-on type liquid silicon rubber B component and 25% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 1500r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three is inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification uses staged
Carry out, solidify the first stage, solidification temperature is 70 DEG C, and hardening time is 6 minutes；Solidifying second stage, solidification temperature is 76 DEG C,
Hardening time is 8 minutes；Solidify the phase III, solidification temperature is 83 DEG C, and hardening time is 10 minutes；Solidify fourth stage, Gu
It is 90 DEG C to change temperature, and hardening time is 16 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
By said process, the sample 4 of medical tea oil dressing finished product is obtained.
Embodiment 5
A kind of production method of medical tea oil dressing, specifically comprises the following steps：
A. according to mass percent meter, 85% injection add-on type liquid silicon rubber component A and 15% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 2200r/min, obtains mixture one；
B. according to mass percent meter, 85% injection add-on type liquid silicon rubber B component and 15% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 2200r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three is inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification uses staged
Carry out, solidify the first stage, solidification temperature is 70 DEG C, and hardening time is 6 minutes；Solidifying second stage, solidification temperature is 76 DEG C,
Hardening time is 8 minutes；Solidify the phase III, solidification temperature is 83 DEG C, and hardening time is 10 minutes；Solidify fourth stage, Gu
It is 90 DEG C to change temperature, and hardening time is 16 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
By said process, the sample 5 of medical tea oil dressing finished product is obtained.
Embodiment 6
A kind of production method of medical tea oil dressing, specifically comprises the following steps：
A. according to mass percent meter, 95% injection add-on type liquid silicon rubber component A and 5% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 3000r/min, obtains mixture one；
B. according to mass percent meter, 95% injection add-on type liquid silicon rubber B component and 5% camellia oil are taken,
It is mixed evenly at normal temperatures, mixing speed 3000r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, mixes stir at normal temperatures
Mix uniformly, mixing speed 500r/min, obtain mixture three；
D. mixture three is inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification uses staged
Carry out, solidify the first stage, solidification temperature is 70 DEG C, and hardening time is 6 minutes；Solidifying second stage, solidification temperature is 76 DEG C,
Hardening time is 8 minutes；Solidify the phase III, solidification temperature is 83 DEG C, and hardening time is 10 minutes；Solidify fourth stage, Gu
It is 90 DEG C to change temperature, and hardening time is 16 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, cured
With tea oil dressing finished product.
By said process, the sample 6 of medical tea oil dressing finished product is obtained.
Sample 1, sample 2, sample 3, sample 4, sample 5 and the sample 6 that above-described embodiment obtains are taken respectively, and another enchashment has skill
Produced under art, and the normal gauze sample 7 of commercially conventional medical dressing, synthetic fibers class dressing sample 8, more poly films
Class dressing sample 9 and foaming polymer class dressing sample 10, and tried respectively by 100 suitable burned patients of degree
Test, every kind of dressing sample is separately to the wound of 10 burned patients, and above-mentioned ten kinds of samples of test are suffered from for burn and scald
The effect of person's wound and healing time, meanwhile, then the resistance bacterium performance and compactness of above-mentioned ten kinds of sample materials in itself are tested respectively,
Following result is drawn by corresponding Experimental Comparison：
First, the resistance bacterium performance of sample 1, sample 2, sample 3, sample 4, sample 5 and sample 6 is slightly above sample 7 and sample
8, it is suitable with sample 9 and sample 10, therefore the medical tea oil dressing that this method is produced has the effect of excellent anti-inflammation；
Secondly, the compactness of sample 1, sample 2, sample 3, sample 4, sample 5 and sample 6 is all higher than sample 7, sample 8 and sample 9, with
Sample 10 is suitable, and the medical tea oil dressing that this method is produced has the effect of excellent hemostasis, and energy wound offer one is wet
The environment of profit promotes its healing, and adhesion wound in use, reduces the pain of patient when changing, is especially suitable for burn and scald
Patient use；Result of the test is carried out finally, for the suitable burned patient of 100 degree, can clearly draw, make
Sample 7, sample are significantly lower than with the average time of the healing of the patient of sample 1, sample 2, sample 3, sample 4, sample 5 and sample 6
Product 8, sample 9 and sample 10, thus this method produce medical tea oil dressing for burned patient wound aggreggate utility and
Promote the time of healing, hence it is evident that excellent and sample 7, sample 8, sample 9 and sample 10.For synthesis, sample 1, sample 2, sample 3,
The combination property of sample 4, sample 5 and each side of sample 6 is all higher than sample 7, sample 8, sample 9 and sample 10, it is possible thereby to see
Go out, for method of the invention compared with the production under prior art, superiority is fairly obvious, and the product of production has marked improvement
The present invention compared with prior art, first, under certain condition by certain mass than injection add-on type liquid
Silicon rubber component A and B component are first each well mixed with camellia oil, and are well mixed mutually under certain condition and are inputted salivation
Machine carries out salivation film forming, and solidifies under the temperature and time of specific selection, then is cured by the step such as cutting and winding
With tea oil dressing finished product, it is possible thereby to become apparent from that this method is simple and efficient, the time short production efficiency of cost is high；Its
It is secondary, add camellia oil in the present invention, and by stir first by camellia oil respectively with injection add-on type liquid silicon rubber component A and
B component is well mixed, then both are well mixed and salivated, and camellia oil is participated in the formation of silicon rubber film, by camellia
Oil is evenly distributed in silicon rubber film, and camellia oil is merged completely in medical tea oil by solidifying, cutting and wind etc.
In dressing finished product, so as to using the correlation properties medical tea oil dressing that makes to produce of camellia oil have excellent anti-inflammation and
The effect of hemostasis；Again, medical artificial skin finished product residual organic solvent is eliminated without using organic solvent in process of production
Possibility, solve organic solvent and volatilize in process of production and endangered with waste liquid to caused by environment, so as to more safety and environmental protection,
To human body and environment non-hazardous, also, the nontoxic no sensitization of artificial skin so produced, with the skin biology of human body in itself
Compatibility is good；Finally, just because of being added separately to inject add-on type liquid silicon rubber component A and B component by camellia oil, and by two
Person is well mixed and salivated, and therefore, is salivated by this species specific blending constituent and solidifies caused medical tea oil dressing
There is preferable compactness, not and resistance bacterium performance is especially excellent, moreover it is possible to which the environment that a moistening is provided to wound promotes its healing, together
When, medical tea oil dressing that this method is produced can realize with wound adhesion, significantly reduce pain during changing medicine for patient.Always
For body, the present invention is simple and efficient, and production efficiency is high, meanwhile, the medical tea oil dressing that this method is produced has excellent resist
The effect of bacterium anti-inflammatory and hemostasis, and the environment that a moistening can be provided to wound promotes its healing, and in use not
Adhesion wound, the pain of patient when changing is reduced, the patient for being especially suitable for burn and scald uses.
Further, in step A, B and C, it is specific selection injection add-on type liquid silicon rubber component A and B groups and
The combined amount of camellia oil, and select to be mixed under optimum temperature and stirring condition uniformly, it can so improve medical tea
The uniformity of oily dressing finished product, so as to optimize the quality for producing medical tea oil dressing finished product, lift its anti-inflammation and hemostasis
The effect of, provide an optimum environment to wound.
Further, in step D, using stepwise being solidified, join in combination with optimum temperature and time
Number, these parameters are all the optimized parameters by largely testing and attempting just to draw, have high practicality, by optimal
The temperature and time condition of change is solidified, and is dramatically improved the molding effect of medical tea oil dressing finished product, is made it more frivolous, more
It is easy to the processing such as follow-up shearing, is more convenient for using as burn and scald dressing in the case of various, meanwhile, lift further lifting
The effect of material anti-inflammation itself and hemostasis, and it is not easy adhesion wound, reduce the pain of patient when changing.
The technical characteristics and general principle and associated advantages of the present invention are the foregoing described, for those skilled in the art
For, it is clear that the invention is not restricted to the details of above-mentioned one exemplary embodiment, and it is in the design without departing substantially from the present invention or substantially special
In the case of sign, the present invention can be realized in other specific forms.Therefore, all should be by embodiment no matter from the point of view of which point
To regard exemplary as, and be nonrestrictive, the scope of the present invention is limited by appended claims rather than described above,
It is intended that all changes fallen in the implication and scope of the equivalency of claim are included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It is appreciated that other embodiment.
Claims (3)
1. a kind of production method of medical tea oil dressing, it is characterised in that specifically comprise the following steps：
A. according to mass percent meter, that takes 75-95% injects add-on type liquid silicon rubber component A and 5-25% camellia
Oil, it is mixed evenly at normal temperatures, mixing speed 1500-3000r/min, obtains mixture one；
B. according to mass percent meter, that takes 75-95% injects add-on type liquid silicon rubber B component and 5-25% camellia
Oil, it is mixed evenly at normal temperatures, mixing speed 1500-3000r/min, obtains mixture two；
C. according to mass percent meter, the mixture two of 50% mixture one and 50% is taken, is mixed at normal temperatures equal
It is even, mixing speed 500r/min, obtain mixture three；
D. mixture three being inputted into slobbering machine and carries out salivation film forming, solidified after salivating film forming, solidification temperature is 70-90 DEG C,
Hardening time is 35-45 minutes, obtains silicon rubber film；
E. silicon rubber film is carried out by blower fan air-cooled, cut after air-cooled, wound again after cutting, obtain medical tea
Oily dressing finished product.
A kind of 2. production method of medical tea oil dressing according to claim 1, it is characterised in that in step, according to
Mass percent meter, 85% injection add-on type liquid silicon rubber component A and 15% camellia oil are taken, mixing at normal temperatures is stirred
Mix uniformly, mixing speed 2200r/min, obtain mixture one；In stepb, according to mass percent meter, 85% is taken
Add-on type liquid silicon rubber B component and 15% camellia oil are injected, is mixed evenly at normal temperatures, mixing speed 2200r/
Min, obtain mixture two；In step C, according to mass percent meter, the mixture of 50% mixture one and 50% is taken
Two, it is mixed evenly at normal temperatures, mixing speed 500r/min, obtains mixture three.
A kind of 3. production method of medical tea oil dressing according to claim 1, it is characterised in that in step D, solidification
Carried out using staged, solidify the first stage, solidification temperature is 70 DEG C, and hardening time is 6 minutes；Solidify second stage, solidification
Temperature is 76 DEG C, and hardening time is 8 minutes；Solidify the phase III, solidification temperature is 83 DEG C, and hardening time is 10 minutes；Solidification
Fourth stage, solidification temperature are 90 DEG C, and hardening time is 16 minutes.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110292231A (en) * | 2019-06-10 | 2019-10-01 | 天津大学 | A kind of tea grounds material silica gel composite insole and preparation method thereof |
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Inventor after: Guo Yong Inventor after: Xia Hesheng Inventor after: Li Xuebo Inventor after: He Xianwen Inventor before: Guo Yong Inventor before: Xia Hesheng Inventor before: Luo Gaoxing Inventor before: Li Xuebo Inventor before: He Xianwen Inventor before: Zeng Fanping |
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Application publication date: 20171201 |