CN107412443A - A kind of linseed oil compositions and preparation method thereof - Google Patents
A kind of linseed oil compositions and preparation method thereof Download PDFInfo
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- CN107412443A CN107412443A CN201710759239.0A CN201710759239A CN107412443A CN 107412443 A CN107412443 A CN 107412443A CN 201710759239 A CN201710759239 A CN 201710759239A CN 107412443 A CN107412443 A CN 107412443A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
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Abstract
The present invention provides a kind of linseed oil compositions, and it is prepared by the raw material of following parts by weight：It is characterized in that preparation method is：15 25 parts of linseed oil, 5 10 parts of bata-carotene, 38 parts of blueberry extract, 58 parts of cassia seed extract, 46 parts of Prunella vulgaris extract, 58 parts of mulberry-leaf extract, 48 parts of wolfberry fruit extract, are prepared into soft capsule, and can improve linseed oil causes to suffer from diarrhoea.
Description
Technical field
The present invention relates to technical field of extraction of Chinese traditional medicine, and in particular to a kind of linseed oil compositions and preparation method thereof.
Background technology
Linseed oil is produced by linseed and formed, and linseed is the seed of flax, belongs to flax family (Linaceae), nickname flax, because it is former
Originate in East India area, Han dynasty Zhang Qian send as an envoy to the Western Regions when, flax is taken back into China through the Silk Road, mainly planted in old times Xiongnu
One band, is the area of " Notherna barbarin tribes in ancient China " aggregation, therefore and gains the name.Linseed belongs to traditional oil crops in China, and flax is divided into oil
With flax, with flax, oil seed flax seed mainly originates from Changbai Mountain song-Nen plain and black in China for Oil and Fibre Flax and fiber
Longjiang area, the Inner Mongol, from Liupan Mountain of Ningxia area, Zhangjiakou Ba Shang Zhangbei County；Inner Mongolian grassland distribution is most, and northeast is a small amount of
Plantation etc..Although flax possesses anti-barren habit, oil seed flax is used as, it is " weather that cools, plentiful soil, sufficient
Three conditions of illumination " must be indispensable.Plantation is cultivated within thousand by locals to find：The Northwest's day and night temperature is balanced, fertile
The natural ecological environment such as soil and the sunlight of abundance is best suitable for the plantation of the special oil crops such as flax, and the category whole nation is without industry
Contaminated zone, northwest ground Xinjiang, Gansu, the linseed oil oil content of West Inner Mongolia area production is up to more than 56%, wherein alpha-linolenic acid
Content is even more to be far above other growing areas, and linseed oil activity is also to top the list.The ground such as Xinjiang, Gansu, Ningxia, Inner Mongol, Shanxi, when
Ground is also known as siritch, mainly due to be ancient times Han dynasty Zhang Qian send as an envoy to Middle East be passed to China.Cold pressed flax seed oil contains rich
Rich alpha-linolenic acid, it is the linolenic most effectual way of supplement.Linseed oil easily causes diarrhoea in the prior art, it has not been convenient to
Take, had a strong impact on that this product is clinically applied.
The content of the invention
Goal of the invention：In order to solve the above problems, it is an object of the invention to provide a kind of linseed oil extracting method and Asia
Sesame oil soft capsule.
Technical scheme：The purpose of the present invention is realized by following scheme：
A kind of linseed oil compositions, it is prepared by the raw material of following parts by weight：It is characterized in that preparation method
For：Linseed oil 15-25 parts, beta carotene 5-10 parts, blueberry extract 3-8 parts, cassia seed extract 5-8 parts, selfheal carry
Take thing 4-6 parts, mulberry-leaf extract 5-8 parts, wolfberry fruit extract 4-8 parts.
The linseed oil compositions, it is prepared by the raw material of following parts by weight：It is characterized in that preparation method
For：20 parts of linseed oil, 8 parts of beta carotene, 5 parts of blueberry extract, 7 parts of cassia seed extract, 5 parts of Prunella vulgaris extract, mulberry
6 parts of leaf extract, 6 parts of wolfberry fruit extract.
The linseed oil compositions, preparation method comprise the following steps：Take blueberry, cassia seed, selfheal, mulberry leaf, Chinese holly
Qi, add water to cook respectively three times, the decocting of 11 times of first time dosing material weight is boiled 3 hours, the water of second of 9 times of dosing material weight
Decoct 2 hours, the decocting of 7 times of third time dosing material weight is boiled 1.5 hours；Extract solution filters, and filtrate is 2.5kPa in pressure, temperature
Spend the thick paste that relative density is 1.35~1.38 when obtaining 60 DEG C for the 12h that is concentrated under reduced pressure under the conditions of 80 DEG C, vacuum drying, with flax
Seed oil, beta carotene are prepared into soft capsule.
Application of the linseed oil compositions in preparing improvement linseed oil and causing diarrhoea health products.
In the prior art, linseed oil easily causes diarrhoea in the prior art, it has not been convenient to takes, has had a strong impact on that this product exists
Clinically apply, the present invention can improve to suffer from diarrhoea caused by linseed oil.
Embodiment
Form by the following examples, the above of the present invention is described in further detail again, but should not be by this
The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1：Take 15 parts of linseed oil, 10 parts of beta carotene, 3 parts of blueberry extract, 8 parts of cassia seed extract, summer
4 parts of withered grass extract, 8 parts of mulberry-leaf extract, 4 parts of wolfberry fruit extract, blueberry, cassia seed, selfheal, mulberry leaf, matrimony vine, add respectively
Decocting is boiled three times, and the decocting of 11 times of first time dosing material weight is boiled 3 hours, and it is small that the decocting of second of 9 times of dosing material weight boils 2
When, the decocting of 7 times of third time dosing material weight is boiled 1.5 hours；Extract solution filters, and filtrate is 2.5kPa in pressure, temperature 80
The 12h that is concentrated under reduced pressure under the conditions of DEG C obtains the thick paste that relative density at 60 DEG C is 1.35~1.38, vacuum drying, with linseed oil,
Beta carotene is prepared into soft capsule.
Embodiment 2：Take 25 parts of linseed oil, 5 parts of beta carotene, 8 parts of blueberry extract, 5 parts of cassia seed extract, summer
6 parts of withered grass extract, 5 parts of mulberry-leaf extract, 8 parts of wolfberry fruit extract, blueberry, cassia seed, selfheal, mulberry leaf, matrimony vine, add respectively
Decocting is boiled three times, and the decocting of 11 times of first time dosing material weight is boiled 3 hours, and it is small that the decocting of second of 9 times of dosing material weight boils 2
When, the decocting of 7 times of third time dosing material weight is boiled 1.5 hours；Extract solution filters, and filtrate is 2.5kPa in pressure, temperature 80
The 12h that is concentrated under reduced pressure under the conditions of DEG C obtains the thick paste that relative density at 60 DEG C is 1.35~1.38, vacuum drying, with linseed oil,
Beta carotene is prepared into soft capsule.
Embodiment 3：Take 20 parts of linseed oil, 8 parts of beta carotene, 5 parts of blueberry extract, 7 parts of cassia seed extract, summer
5 parts of withered grass extract, 6 parts of mulberry-leaf extract, 6 parts of wolfberry fruit extract, blueberry, cassia seed, selfheal, mulberry leaf, matrimony vine, add respectively
Decocting is boiled three times, and the decocting of 11 times of first time dosing material weight is boiled 3 hours, and it is small that the decocting of second of 9 times of dosing material weight boils 2
When, the decocting of 7 times of third time dosing material weight is boiled 1.5 hours；Extract solution filters, and filtrate is 2.5kPa in pressure, temperature 80
The 12h that is concentrated under reduced pressure under the conditions of DEG C obtains the thick paste that relative density at 60 DEG C is 1.35~1.38, vacuum drying, with linseed oil,
Beta carotene is prepared into soft capsule.
Embodiment 4：Experimental study data of the present invention to diarrhoea
Experimental agents：The present invention is prepared by embodiment 1-3 methods, control group is soft capsule prepared by independent linseed oil.
Experimentation：20-22 grams of mouse 40 is taken, is divided into 4 groups, respectively embodiment 1-3 groups and control group, every mouse
0.5 gram of gavage soft capsule content, observe defecation weight in 8 hours.It the results are shown in Table：
Each embodiment defecation weight measurement result
| Sample source | Defecation weight (g) in 8 hours |
| Embodiment 1 | 0.82±0.13 |
| Embodiment 2 | 0.85±0.12 |
| Embodiment 3 | 0.76±0.15 |
| Control group | 1.46±0.32 |
It can improve flax according to the results showed that embodiment of the present invention 1-3 of the upper table linseed oil compositions prepared
Suffered from diarrhoea caused by seed oil.
Claims (4)
1. a kind of linseed oil compositions, it is characterised in that it is prepared by the raw material of following parts by weight：It is characterized in that
Preparation method is：Linseed oil 15-25 parts, beta carotene 5-10 parts, blueberry extract 3-8 parts, cassia seed extract 5-8 parts,
Prunella vulgaris extract 4-6 parts, mulberry-leaf extract 5-8 parts, wolfberry fruit extract 4-8 parts.
2. linseed oil compositions according to claim 1, it is characterised in that it is prepared into by the raw material of following parts by weight
Arrive：It is characterized in that preparation method is：20 parts of linseed oil, 8 parts of beta carotene, 5 parts of blueberry extract, cassia seed extract 7
Part, 5 parts of Prunella vulgaris extract, 6 parts of mulberry-leaf extract, 6 parts of wolfberry fruit extract.
3. linseed oil compositions according to claim 1, it is characterised in that preparation method comprises the following steps：Take blueberry,
Cassia seed, selfheal, mulberry leaf, matrimony vine, adding water to cook respectively three times, the decocting of 11 times of first time dosing material weight is boiled 3 hours, the
The decocting of secondary 9 times of dosing material weight is boiled 2 hours, and the decocting of 7 times of third time dosing material weight is boiled 1.5 hours；Extract solution filters,
Filtrate is 2.5kPa in pressure, temperature be concentrated under reduced pressure under the conditions of being 80 DEG C 12h when obtaining 60 DEG C relative density be 1.35~1.38
Thick paste, vacuum drying, be prepared into soft capsule with linseed oil, beta carotene.
4. application of the linseed oil compositions in improving linseed oil and causing diarrhoea health products according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710759239.0A CN107412443A (en) | 2017-08-30 | 2017-08-30 | A kind of linseed oil compositions and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710759239.0A CN107412443A (en) | 2017-08-30 | 2017-08-30 | A kind of linseed oil compositions and preparation method thereof |
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| Publication Number | Publication Date |
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| CN107412443A true CN107412443A (en) | 2017-12-01 |
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| CN201710759239.0A Withdrawn CN107412443A (en) | 2017-08-30 | 2017-08-30 | A kind of linseed oil compositions and preparation method thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104046511A (en) * | 2014-07-09 | 2014-09-17 | 宁夏六盘珍坊生态农业科技有限公司 | Linseed oil preparation method for improving quality of linseed oil |
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2017
- 2017-08-30 CN CN201710759239.0A patent/CN107412443A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104046511A (en) * | 2014-07-09 | 2014-09-17 | 宁夏六盘珍坊生态农业科技有限公司 | Linseed oil preparation method for improving quality of linseed oil |
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| PB01 | Publication | ||
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| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20171201 |
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| WW01 | Invention patent application withdrawn after publication |