CN107412073A - A kind of composition containing peach gum hydrolysate and its preparation method and application - Google Patents

A kind of composition containing peach gum hydrolysate and its preparation method and application Download PDF

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Publication number
CN107412073A
CN107412073A CN201710763385.0A CN201710763385A CN107412073A CN 107412073 A CN107412073 A CN 107412073A CN 201710763385 A CN201710763385 A CN 201710763385A CN 107412073 A CN107412073 A CN 107412073A
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mass ratio
oil
mixture
composition
peach gum
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章苏宁
侯筱婷
苏畅
彭邦婷
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Shanghai Institute of Technology
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Shanghai Institute of Technology
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Life Sciences & Earth Sciences (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of composition containing peach gum hydrolysate, and using weight proportion to calculate, 20 30 parts of peach gum hydrolysate, 20 30 parts of the yeast extract of Noni fruit zymotic fluid, surplus is deionized water.Present invention also offers the face cream containing above-mentioned composition, facial treatment milk and toner.Present invention also offers purposes of the combinations of the above thing as skin barrier renovation agent.The skin of gained of the invention applies some make up and can also form skin barrier while having no side effect with natural safety, while helps skin to carry out maintenance.

Description

A kind of composition containing peach gum hydrolysate and its preparation method and application
Technical field
The invention belongs to filed of daily-use chemical industry, is related to a kind of cosmetics, specifically a kind of containing peach gum hydrolysate Composition and its preparation method and application.
Background technology
Peach gum, it is the polysaccharide natural gum being secreted in the barks such as rosaceous plant peach or mountain peach, containing a variety of natural The natural products beneficial to human body such as polysaccharide, protein, galactolipin.The traditional Chinese medical science thinks, peach gum have heat-clearing, quench the thirst, relieve pain analgesia, The effect of beauty treatment, anti-aging.The diseases such as urolithiasis, blood strangury, dysentery are cured mainly, are used since ancient times as medicine and health products.
Noni fruit is the fruit in the torrid zone, is rather converted rich in vitamin, mineral matter, amino acid, alkaloid, polysaccharides, celo The composition of the great medical value such as enzyme, it is nutritious.According to modern medicine study, it has antioxidation activity and protection cardiac muscle thin Born of the same parents act on, and can adjust damaged myocardium cellular energy metabolism, are a kind of safe medicines for delaying heart failure process, have simultaneously Good senile-resistant efficacy.
The problem of peach gum can run into some in the use of cosmetics at present, such as conventional edible peach gum are not soluble in water In, it is impossible to it is directly appended in cosmetics.
Although there is application of the peach gum product as NMF in skin care item at present, it does not have this composition and had Skin barrier protective effect, at present also there is not yet it is applied to during skin applies some make up as skin barrier skin barrier renovation agent Research report.
The content of the invention
For above-mentioned technical problem of the prior art, the invention provides a kind of composition containing peach gum hydrolysate and Its preparation method and application, the described this composition containing peach gum hydrolysate and its preparation method and application will solve existing Cosmetics in technology repair the indifferent technical problem of skin.
The invention provides a kind of composition containing peach gum hydrolysate, by the raw material preparation of following weight Into：
Peach gum hydrolysate 20-30 parts,
Yeast extract 20-30 parts of Noni fruit zymotic fluid,
Deionized water surplus；
The peach gum hydrolysate is made up of following methods：Dry after peach gum is cleaned, added after being smashed with mixer Temperature is 80~95 DEG C, in the sodium hydroxide solution of pH=10~11, and the mass ratio of peach gum and sodium hydroxide solution is 3：9~ 100；Hydrolysis is dried after 3~8 hours and obtained；
The yeast extract of the Noni fruit zymotic fluid is passes through the yeast that obtains of yeast fermentation with Noni fruit by substrate Fungus extract.
Further, the yeast extract of the Noni fruit zymotic fluid is prepared by the following method and obtained：By the beautiful fresh fruit of promise With smashing after being cut into small pieces, pulp diameter 10-30 mesh is smashed, using feed liquid mass ratio as 1:1~2 ratio adds distilled water, goes out It will be added to after bacterium after used yeast actication of culture in the Noni fruit fresh pulp of above-mentioned gained, 25~30 DEG C of ferment at constant temperature 30~ 60h, 80 mesh sievings are carried out after saccharomycete breeding, gained filtrate is centrifuged, and removes a layer product yeast thalline and is gone out It is living, smash, with 0.45 μm of membrane filtration, take filtrate dried for standby.
Present invention also offers a kind of face cream containing the above-mentioned composition containing peach gum hydrolysate, its raw material contains Amount and composition are as follows：
The mass ratio of the mixture that described mineral grease forms for stearic acid and white oil, stearic acid and white oil is 4：1；
Described Synthetic Oil is the mixing of isobutyl palmitate, glycerin monostearate and dimethyl siloxane composition Thing, the mass ratio of isobutyl palmitate, glycerin monostearate and dimethyl siloxane is 6：1：2；
Described natural oil is the mass ratio of the mixture that Sweet Almond Oil and olive oil form, Sweet Almond Oil and olive oil For 1：2；
Described emulsifying agent is the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), match Bick 305 emulsify The mixture of agent composition, the i.e. stearic alcohol ether of polyoxyethylene (2), polyoxyethylene (21) stearic alcohol ether and the match emulsifying agent of Bick 305 Mass ratio is 2：3:3；
The mass ratio of the mixture that described NMF forms for glycerine and butanediol, glycerine and butanediol is 1:3；
Described preservative is the mixture that methyl hydroxybenzoate and propylben form, methyl hydroxybenzoate and nipalgin third The mass ratio of ester is 21；
Described antioxidant is 2,6- di-tert-butyl hydroxy toluenes.
Present invention also offers a kind of preparation method of above-mentioned face cream, comprise the following steps：
1) each raw material is weighed according to mass ratio；
2) oil phase 1 of mineral grease, Synthetic Oil, match Bick 305 emulsifying agent composition is heated to 65-90 DEG C of stirring and dissolving As A1 phases；
3) vegetable fat, the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), antioxidant are formed Oil phase 2 is heated to 65-90 DEG C of stirring and dissolving as A2 phases；
4) composition containing peach gum hydrolysate is dissolved in 10~30% deionized water and is heated to 50-70 DEG C The aqueous phase 1 of insulation is used as B1 phases；
5) NMF is dissolved in the deionized water of surplus, and heating stirring is completely dispersed the uniform conduct of aqueous phase 2 to 65-90 DEG C B2 phases；
6) control temperature that the A1 phases obtained by step 2) and step 3) and A2 are mixed and stirred, is obtained at 70-85 DEG C To total oil phase as A phases；
7) controlling temperature, mixer mixing speed is 500-700rpm/min, by step 5) and step 6) institute at 70-85 DEG C The B2 phases and A obtained is mixed and stirred；
8) it is 500-700rpm/min to control mixer mixing speed, and the mixture obtained by step 7) is cooled into 50- 70 DEG C, then mixed with the B1 obtained by step 4)；
9) under the conditions of controlling homogenizer rotating speed to be 10000-20000rpm/min, by the mixture obtained by step 8) Thing is uniformly dispersed；
10) after step 9) is well mixed, when being naturally cooling to 45 DEG C, preservative is added, continues mechanical agitation to mixing Uniformly；Speed of agitator is 100-500rpm/min；And stop stirring after naturally cooling to room temperature, discharging, produce face cream；
Present invention also offers a kind of facial treatment milk containing the above-mentioned composition containing peach gum hydrolysate, its raw material contains Amount and composition are as follows：
The mass ratio of the mixture that described mineral grease forms for stearic acid and white oil, stearic acid and white oil is 3：1；
Described Synthetic Oil is the mixing of isobutyl palmitate, glycerin monostearate and dimethyl siloxane composition Thing, the mass ratio of isobutyl palmitate, glycerin monostearate and dimethyl siloxane is 6：1：2；
Described natural oil is the mass ratio of the mixture that Sweet Almond Oil and olive oil form, Sweet Almond Oil and olive oil For 1：2；
Described emulsifying agent is the stearic alcohol ether of polyoxyethylene (2), the mixture of the stearic alcohol ether composition of polyoxyethylene (21), is gathered The mass ratio of the stearic alcohol ether of oxygen ethene (2) and polyoxyethylene (21) stearic alcohol ether is 2：3；
The mass ratio of the mixture that described NMF forms for glycerine and 1,3-BDO, glycerine and butanediol is 2:3；
Described rheology control agent is hydroxyethyl cellulose or card ripple；
Described preservative is the mixture that methyl hydroxybenzoate and propylben form, methyl hydroxybenzoate and nipalgin third The mass ratio of ester is 2：1；
Described antioxidant is 2,6- di-tert-butyl hydroxy toluenes.
Present invention also offers a kind of preparation method of facial treatment milk, comprise the following steps：
1) each reaction raw materials are weighed according to mass ratio；
2) by mineral grease, Synthetic Oil, vegetable fat, the stearic alcohol ether of polyoxyethylene (2), polyoxyethylene (21) stearyl alcohol Ether, the oil phase of antioxidant composition are heated to 65-90 DEG C of stirring and dissolving as A phases；
3) composition containing peach gum hydrolysate is dissolved in 10~30% deionized water and is heated to 70 DEG C of guarantors The aqueous phase 1 of temperature is used as B1 phases；
4) rheology control agent and NMF are dissolved in balance deionized water, heating stirring is completely dispersed equal to 65-90 DEG C Even aqueous phase 2 is used as B2 phases；
5) in the case where temperature is 80-90 DEG C, mixer mixing speed is 500-700rpm/min, and step 3) and step 4) are made B1 with the B2 phases obtained be mixed and stirred for uniformly obtaining B phases；
6) controlling temperature, mixer mixing speed is 500-700rpm/min, by step 2) and step 5) institute at 70-85 DEG C The A phases obtained with B phases be mixed and stirred for uniformly；
7) under the conditions of controlling homogenizer rotating speed to be 10000-20000rpm/min, by the mixture obtained by step 6) Thing is uniformly dispersed；
8) after step 7) is well mixed, when being naturally cooling to 45 DEG C, preservative is added, it is equal to mixing to continue mechanical agitation It is even；Speed of agitator is 100-500rpm/min；And stop stirring after naturally cooling to room temperature, discharging, produce facial treatment milk；
Present invention also offers a kind of toner containing the above-mentioned composition containing peach gum hydrolysate, by mass percentage Calculate, the content and composition of its raw material are as follows：
Described solubilizer is rilanit special；
Described rheology control agent is hydroxyethyl cellulose；
Described preservative is the mixture of hydroxyphenyl methyl esters and hydroxyphenyl propyl ester composition, hydroxyphenyl methyl esters and hydroxyphenyl third The mass ratio of ester is 2：1.
Present invention also offers the preparation method of above-mentioned toner, comprise the following steps：
1) each raw material is weighed according to mass ratio；
2) remove ionized water to be added in a reaction vessel, start agitator, rheology control agent is added into reaction holds In device, rheology control agent add finish continue stir 15-20min it is standby；
3) essence, solubilizer and preservative Hybrid Heating are heated to 40~50 DEG C as oil phase and obtain oil phase；
4) composition containing peach gum hydrolysate is added in the deionized water of step 2) and uniformly added as Aqueous dispersions Hot to 45~55 DEG C obtain aqueous phase；
5) aqueous phase obtained by step 4) is cooled to 40~48 DEG C, then the oil phase obtained by step 3) is added to step 4) institute Aqueous phase in, while open mixer, it is 300-500rpm/min control mixing speed, is disperseed, and mechanical agitation is to mixing Close uniformly and stop stirring after naturally cooling to room temperature, discharging, produce toner.
The present invention reduces the molecular weight of peach gum by way of hydrolysis, so as to improve its dissolubility；Noni fruit carries simultaneously Take thing that there is very strong inoxidizability composition, it is nutritious, therefore the hair for preparing saccharomycete of the present invention using Noni fruit as substrate Zymotic fluid, and being extracted to the yeast of generation, by a kind of new cosmetics that are used for of the extract and peach gum hydrolysate composition Composition, said composition have skin barrier protection, maintenance effect.
The present invention compares with prior art, and the composition of the thing of solution containing peach glue of the invention is a kind of ideal natural Skin barrier moisturizing maintenance composition, this composition have synergy.A series of skins prepared using the skin barrier renovation agent Apply some make up with preparation technology simple possible, the characteristics of moisturizing maintenance effect is good, natural safe.The natural skin screen of the present invention Barrier renovation agent is pure natural, safe, has certain skin barrier protecting effect.
Brief description of the drawings
Fig. 1 shows the composition moistening effect figure containing peach gum hydrolysate.
Fig. 2 shows the composition skin barrier maintenance design sketch containing peach gum hydrolysate.
Embodiment
The present invention is expanded on further by way of example and in conjunction with the accompanying drawings, but is not intended to limit the present invention.
Embodiment 1
A kind of composition containing peach gum hydrolysate, is prepared via a method which：
(1), 10g peach gums are cleaned, dried, are crushed.Gained peach gum powder and Ph=10.5 sodium hydroxide solution with Solid-liquid ratio is 3:100 ratio mixing, 5h is hydrolyzed under conditions of being 90 DEG C in temperature, is then dried gained hydrolysate, It is standby to be ground into powder.
The yeast extract of the Noni fruit zymotic fluid is the increased saccharomycete of yeast fermentation using Noni fruit as substrate Extract, it is prepared by the following method and obtains：It is with dry grinding meat grinder that the promise of stripping and slicing is beautiful fresh after the beautiful fresh fruit of 50g promises is cut into small pieces Fruit is smashed, pulp diameter 10-30 mesh, with 1:1 ratio adds distilled water, is added after used yeast strain 2g is activated after sterilizing In the Noni fruit fresh pulp for stating gained, 28 DEG C of ferment at constant temperature 48h, 80 mesh sievings are carried out after saccharomycete breeding, gained filtrate is entered Row centrifuges, and removes a layer product yeast thalline and is inactivated, smashes, with 0.45 μm of membrane filtration, take filtrate dried for standby.
The composition 20g of described skin barrier NMF is mixed to prepare, quality proportioning is：Peach gum hydrolysate 30% is 6g, the yeast extract 30% of Noni fruit zymotic fluid is 6g, balance deionized water 8g.
Application Example 1
A kind of application in face cream, is calculated by mass percentage, and the content and composition of its raw material are as follows：
The composition of described skin barrier renovation agent, weight are：30 parts of peach gum hydrolysate, Noni fruit zymotic fluid 20 parts of yeast extract, surplus is deionized water, i.e. 1.5g peach gums hydrolysate, the yeast extract of 1g Noni fruit zymotic fluids, 2.5g deionized water；
Described mineral grease is the mixture that stearic acid and white oil form, and is calculated in mass ratio, i.e. stearic acid：White oil is 4：1, i.e. 4g stearic acid and 1g white oil；
Described Synthetic Oil is the mixing of isobutyl palmitate, glycerin monostearate and dimethyl siloxane composition Thing, calculate in mass ratio, i.e. isobutyl palmitate：Glycerin monostearate is：Dimethyl siloxane 6：1：2, i.e. palmitic acid is different Monooctyl ester 2g, glycerin monostearate 0.33g, dimethyl siloxane 0.67g；
Described natural oil is that the mixture that Sweet Almond Oil and olive oil form calculates in mass ratio, i.e. Sweet Almond Oil： Olive oil is 1：2, i.e. 1g Sweet Almond Oil and 2g olive oil；
Described emulsifying agent is the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), match Bick 305 emulsify The mixture of agent composition, is calculated, i.e. polyoxyethylene (2) stearic alcohol ether in mass ratio：Polyoxyethylene (21) stearic alcohol ether：Match Bick 305 emulsifying agents are 2：3:3, i.e. 1g polyoxyethylene (2) stearic alcohol ether, the 1.5g stearic alcohol ether of polyoxyethylene (21) and 1.5g's Match the emulsifying agent of Bick 305.
Described NMF is glycerine and butanediol, is calculated in mass ratio, i.e. glycerine：Butanediol is 1:3, i.e. 1g glycerine With 3g butanediol；
Described preservative is methyl hydroxybenzoate and propylben, is calculated in mass ratio, i.e. methyl hydroxybenzoate：Nipalgin Propyl ester is 2：1, i.e. 0.04g methyl hydroxybenzoate and 0.02g ethylparaben.
Described antioxidant is 0.01g 2,6- di-tert-butyl hydroxy toluenes；
A kind of preparation method of above-mentioned face cream containing described composition, specifically comprises the following steps：
(1), by the oil phase 1 of mineral grease, Synthetic Oil, match Bick 305 emulsifying agent composition, to be heated to 65-90 DEG C of stirring molten Solution is used as A1 phases；
(2), vegetable fat, the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), antioxidant are formed Oil phase 2 be heated to 65-90 DEG C of stirring and dissolving as A2 phases；
(3), the composition of the skin barrier renovation agent is dissolved in a small amount of deionized water and is heated to 50-70 DEG C of insulation Aqueous phase 1 be used as B1 phases；
(4), NMF is dissolved in balance deionized water, and heating stirring is completely dispersed the uniform conduct of aqueous phase 2 to 65-90 DEG C B2 phases；
(5), control temperature that the A1 phases obtained by step (1) and step (2) are mixed and stirred with A2 phases at 70-85 DEG C Mix uniformly, total oil phase is made as A phases；
(6), controlling temperature, mixer mixing speed is 500-700rpm/min, by step (4) and step at 70-85 DEG C (5) the B2 phases obtained by with A phases be mixed and stirred for uniformly；
(7) it is 500-700rpm/min, to control mixer mixing speed, and the mixture obtained by step (6) is cooled to 50-70 DEG C, then mixed with the B1 obtained by step (3)；
(8), will be mixed obtained by step (7), under the conditions of controlling homogenizer rotating speed to be 10000-20000rpm/min Compound thing is uniformly dispersed；
(9), after step (8) is well mixed, when being naturally cooling to 45 DEG C, preservative is added, continues mechanical agitation to mixed Close uniform；And stop stirring after naturally cooling to room temperature, discharging, produce a kind of skin care containing the skin barrier renovation agent Frost；
It is 100-500rpm/min. that described mechanical agitation, which controls speed of agitator,
The cream containing composition of above-mentioned gained is evaluated skin moisture-keeping and barrier maintenance effect respectively, its specific step It is rapid as follows
(1) cream for containing the composition in right amount, is taken as testing sample, and takes the phase for being free of the extract in right amount Cream with formula rate is as blank control.
(2) 12 subjects, are selected, area is selected respectively in every subject's left hand and right hand inner forearm same position 3cm*3cm tested region.
It it is 20 DEG C in temperature, 15min is dried in the interior that air humidity is 50% with the distillation tested region 30s of water wash.
Surveyed respectively using MPA580 skinanalysis apparatus skin water content test probe and penetrating moisture loss rate test probe Measure left hand and the keratoderma water content blank value MMV in the tested region of the right hand10And MMV00, left hand and the tested region of the right hand Percutaneous moisture loss rate blank value TEWL10And TEWL00。
The 18mg face cream containing the composition is applied on the tested region of subject's left hand respectively, the right hand does blank Contrast.
After waiting 30min, measure keratoderma the water content MMV11 and MMV01 in two tested regions, left hand and the right hand by Try the percutaneous moisture loss rate blank value TEWL in region11And TEWL01。
After again waiting for 60min, keratoderma the water content MMV12 and MMV02 in two tested regions, left hand and the right side are measured The percutaneous moisture loss rate blank value TEWL in the tested region of hand12And TEWL02。
Such as Fig. 1, MMV value changes curves are obtained, it can be seen that the MMV values after using the composition solution containing peach gum hydrolysate There is obvious rising and be higher than blank group, it is known that the composition containing peach gum hydrolysate has certain moisture-keeping function；Basis simultaneously Figure two can be seen that, use the cream after the addition composition to have more skin than the blank cream containing same dosage NMF Skin barrier protection acts on, and can effectively reduce the lost speed of moisture of skin, and the resistance for strengthening skin repairs power and self-protection energy Power, and contain glycerine and propane diols as the blank cream of NMF and acted on without skin barrier.
Application Example 2
A kind of facial treatment milk, the content and composition of its raw material are as follows：
The composition of described skin barrier renovation agent, weight are：30 parts of peach gum hydrolysate, Noni fruit zymotic fluid 20 parts of yeast extract, surplus is deionized water, i.e. 1.5g peach gums hydrolysate, the yeast extract of 1g Noni fruit zymotic fluids, 2.5g deionized water；
Described mineral grease is the mixture that stearic acid and white oil form, and is calculated in mass ratio, i.e. stearic acid：White oil is 3：1 i.e. 3g stearic acid and 1g white oil；
Described Synthetic Oil is the mixing of isobutyl palmitate, glycerin monostearate and dimethyl siloxane composition Thing, calculate in mass ratio, i.e. isobutyl palmitate：Glycerin monostearate：Dimethyl siloxane 6：1：2, i.e. 2g palmitic acid Different monooctyl ester, 0.33g glycerin monostearate and 0.6g dimethyl siloxane；
Described natural oil is that the mixture that Sweet Almond Oil and olive oil form calculates in mass ratio, i.e. Sweet Almond Oil： Olive oil is 1：2, i.e. 1g Sweet Almond Oil and 2g olive oil；
Described emulsifying agent is the stearic alcohol ether of polyoxyethylene (2), the mixture of the stearic alcohol ether composition of polyoxyethylene (21), is pressed Mass ratio calculates, i.e. polyoxyethylene (2) stearic alcohol ether：Polyoxyethylene (21) stearic alcohol ether is 2：3, i.e. 1g polyoxyethylene (2) Polyoxyethylene (21) stearic alcohol ether of stearic alcohol ether and 1.5g；
Described NMF is glycerine and 1,3-BDO, is calculated in mass ratio, i.e. glycerine：Butanediol is 2:3, i.e. 2g's The butanediol of glycerine and 3g.
The rheology-modifying street is 0.5g hydroxyethyl celluloses；
Described preservative is methyl hydroxybenzoate and propylben, is calculated in mass ratio, i.e. methyl hydroxybenzoate：Nipalgin Propyl ester is 2：1；
Described antioxidant is 2,6- di-tert-butyl hydroxy toluenes.
A kind of preparation method of above-mentioned emulsion containing the composition, comprises the following steps：
(1) it is, that mineral grease, Synthetic Oil, vegetable fat, the stearic alcohol ether of polyoxyethylene (2), polyoxyethylene (21) is stearic Alcohol ether, the oil phase 2 of antioxidant composition are heated to 65-90 DEG C of stirring and dissolving as A phases；
(2), the composition is dissolved in a small amount of deionized water and is heated to the aqueous phase 1 of 70 DEG C of insulations as B1 phases；
(3), rheology control agent and NMF are dissolved in balance deionized water, heating stirring is completely dispersed to 65-90 DEG C Uniform aqueous phase 2 is used as B2 phases；
(4), in the case where temperature is 80-90 DEG C, mixer mixing speed is 500-700rpm/min, by step (2) and step (3) B1 with B2 phases made from be mixed and stirred for uniformly；
(5), controlling temperature, mixer mixing speed is 500-700rpm/min, by step (1) and step at 70-85 DEG C (4) the A phases obtained by with B phases be mixed and stirred for uniformly；
(8), will be mixed obtained by step (7), under the conditions of controlling homogenizer rotating speed to be 10000-20000rpm/min Compound thing is uniformly dispersed；
(9), after step (8) is well mixed, when being naturally cooling to 45 DEG C, preservative is added, continues mechanical agitation to mixed Close uniform；And stop stirring after naturally cooling to room temperature, discharging, produce one kind and contain the composition as skin barrier reparation The facial treatment milk of agent；
It is 100-500rpm/min. that described mechanical agitation, which controls speed of agitator,
Application Example 3
A kind of toner, is calculated by mass percentage, and the content and composition of its raw material are as follows：
The composition, weight are：30 parts of peach gum hydrolysate, 20 parts of the yeast extract of Noni fruit zymotic fluid, Surplus is deionized water, i.e. 1.5g peach gums hydrolysate, the yeast extract of 1g Noni fruit zymotic fluids, 2.5g deionized waters；
Described solubilizer is 0.5g rilanit specials；
Described rheology control agent is 0.5g hydroxyethyl celluloses；
Described preservative is the mixture of hydroxyphenyl methyl esters and hydroxyphenyl propyl ester composition, is calculated in mass ratio, i.e. oxybenzene Base methyl esters：Hydroxyphenyl propyl ester is 2：1, i.e. the hydroxypropyl propyl ester of 0.04g hydroxypropyls methyl esters and 0.02g.
Described essence is 0.01g commercially available essence used for cosmetic.
A kind of preparation method of the toner of above-mentioned composition containing skin barrier NMF, comprises the following steps：
(1), take a certain amount of deionized water to start agitator in beaker, rheology control agent is slowly poured into beaker, flow Become conditioning agent add finish continue stir 15-20min it is standby；
(2) essence, solubilizer and preservative Hybrid Heating, are heated to 45 DEG C as oil phase and obtain oil phase；
(3), the composition containing peach gum hydrolysate is added to uniform as Aqueous dispersions in the deionized water of step (1) It is heated to 70 DEG C and obtains aqueous phase；
(4) aqueous phase obtained by step (3), is cooled to 45 DEG C, then the oil phase obtained by step (2) is added to step (3) In the aqueous phase of gained, while mixer is opened, it is 300-500rpm/min to control mixing speed, carries out scattered 10min, and machinery stirs Mix to well mixed and naturally cool to after room temperature and stop stirring, discharging, produce a kind of containing as skin barrier renovation agent The toner of composition.

Claims (9)

1. a kind of composition containing peach gum hydrolysate, it is characterised in that be prepared by the raw material of following parts by weight：
Peach gum hydrolysate 20-30 parts,
Yeast extract 20-30 parts of Noni fruit zymotic fluid,
Deionized water surplus；
The peach gum hydrolysate is made up of following methods：Dry after peach gum is cleaned, added after being smashed with mixer in temperature For in 80~95 DEG C, the sodium hydroxide solutions of pH=10~11, the mass ratio of peach gum and sodium hydroxide solution is 3：9~100；Water Solution is dried after 3~8 hours and obtained；
The yeast extract of the Noni fruit zymotic fluid carries for the saccharomycete obtained with Noni fruit by substrate by yeast fermentation Take thing.
2. according to a kind of composition containing peach gum hydrolysate of the requirement of right 1, it is characterised in that the Noni fruit zymotic fluid Yeast extract is prepared by the following method and obtained：With smashing after the beautiful fresh fruit of promise is cut into small pieces, the pulp diameter 10- after smashing 30 mesh, using feed liquid mass ratio as 1:1~2 ratio adds distilled water, will be added to after sterilizing after used yeast actication of culture In the Noni fruit fresh pulp for stating gained, 25~30 DEG C of 30~60h of ferment at constant temperature, 80 mesh sievings, institute are carried out after saccharomycete breeding Obtain filtrate to be centrifuged, remove a layer product yeast thalline and inactivated, smash, with 0.45 μm of membrane filtration, take filtrate to dry It is stand-by.
3. a kind of face cream of the composition containing peach gum hydrolysate containing described in claim 1, it is characterised in that by quality Percentage calculates, and the content and composition of its raw material are as follows：
The mass ratio of the mixture that described mineral grease forms for stearic acid and white oil, stearic acid and white oil is 4：1；
Described Synthetic Oil is the mixture of isobutyl palmitate, glycerin monostearate and dimethyl siloxane composition, brown The mass ratio of the different monooctyl ester of palmitic acid acid, glycerin monostearate and dimethyl siloxane is 6：1：2；
The mass ratio of the mixture that described natural oil forms for Sweet Almond Oil and olive oil, Sweet Almond Oil and olive oil is 1： 2；
Described emulsifying agent is the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), the match emulsifying agent group of Bick 305 Into mixture, i.e., the stearic alcohol ether of polyoxyethylene (2), polyoxyethylene (21) stearic alcohol ether and match the emulsifying agent of Bick 305 quality Than for 2：3:3；
The mass ratio of the mixture that described NMF forms for glycerine and butanediol, glycerine and butanediol is 1:3；
The mixture that described preservative forms for methyl hydroxybenzoate and propylben, methyl hydroxybenzoate and propylben Mass ratio is 21；
Described antioxidant is 2,6- di-tert-butyl hydroxy toluenes.
4. the preparation method of a kind of face cream described in claim 3, it is characterised in that comprise the following steps：
1) each raw material is weighed according to mass ratio；
2) using mineral grease, Synthetic Oil, match Bick 305 emulsifying agent composition oil phase 1 be heated to 65-90 DEG C of stirring and dissolving as A1 phases；
3) oil phase 2 for forming vegetable fat, the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), antioxidant 65-90 DEG C of stirring and dissolving is heated to as A2 phases；
4) composition containing peach gum hydrolysate is dissolved in 10~30% deionized water and is heated to 50-70 DEG C of insulation Aqueous phase 1 be used as B1 phases；
5) NMF is dissolved in the deionized water of surplus, and heating stirring is completely dispersed uniform aqueous phase 2 to 65-90 DEG C and is used as B2 Phase；
6) control temperature that the A1 phases obtained by step 2) and step 3) and A2 are mixed and stirred at 70-85 DEG C, obtain total Oil phase is as A phases；
7) controlling temperature, mixer mixing speed is 500-700rpm/min at 70-85 DEG C, by obtained by step 5) and step 6) B2 phases and A are mixed and stirred；
8) it is 500-700rpm/min to control mixer mixing speed, and the mixture obtained by step 7) is cooled into 50-70 DEG C, Then mixed with the B1 obtained by step 4)；
9) under the conditions of controlling homogenizer rotating speed to be 10000-20000rpm/min, by the mixture thing point obtained by step 8) Dissipate uniform；
10) after step 9) is well mixed, when being naturally cooling to 45 DEG C, preservative is added, continues mechanical agitation to well mixed； Speed of agitator is 100-500rpm/min；And stop stirring after naturally cooling to room temperature, discharging, produce face cream.
5. a kind of facial treatment milk of the composition containing containing peach gum hydrolysate described in claim 1, it is characterised in that by quality Percentage calculates, and the content and composition of its raw material are as follows：
The mass ratio of the mixture that described mineral grease forms for stearic acid and white oil, stearic acid and white oil is 3：1；
Described Synthetic Oil is the mixture of isobutyl palmitate, glycerin monostearate and dimethyl siloxane composition, brown The mass ratio of the different monooctyl ester of palmitic acid acid, glycerin monostearate and dimethyl siloxane is 6：1：2；
The mass ratio of the mixture that described natural oil forms for Sweet Almond Oil and olive oil, Sweet Almond Oil and olive oil is 1： 2；
Described emulsifying agent is the stearic alcohol ether of polyoxyethylene (2), the mixture of the stearic alcohol ether composition of polyoxyethylene (21), polyoxy second The mass ratio of the stearic alcohol ether of alkene (2) and polyoxyethylene (21) stearic alcohol ether is 2：3；
The mass ratio of the mixture that described NMF forms for glycerine and 1,3-BDO, glycerine and butanediol is 2:3；
Described rheology control agent is hydroxyethyl cellulose or card ripple；
The mixture that described preservative forms for methyl hydroxybenzoate and propylben, methyl hydroxybenzoate and propylben Mass ratio is 2：1；
Described antioxidant is 2,6- di-tert-butyl hydroxy toluenes.
6. the preparation method of a kind of facial treatment milk described in claim 5, it is characterised in that comprise the following steps：
1) each reaction raw materials are weighed according to mass ratio；
2) by mineral grease, Synthetic Oil, vegetable fat, the stearic alcohol ether of polyoxyethylene (2), the stearic alcohol ether of polyoxyethylene (21), The oil phase of antioxidant composition is heated to 65-90 DEG C of stirring and dissolving as A phases；
3) by the composition containing peach gum hydrolysate be dissolved in 10~30% deionized water and be heated to 70 DEG C insulation Aqueous phase 1 is used as B1 phases；
4) rheology control agent and NMF are dissolved in balance deionized water, heating stirring is completely dispersed uniform to 65-90 DEG C Aqueous phase 2 is used as B2 phases；
5) in the case where temperature is 80-90 DEG C, mixer mixing speed is 500-700rpm/min, and step 3) and step 4) is obtained B1 with B2 phases be mixed and stirred for uniformly obtaining B phases；
6) controlling temperature, mixer mixing speed is 500-700rpm/min at 70-85 DEG C, by obtained by step 2) and step 5) A phases with B phases be mixed and stirred for uniformly；
7) under the conditions of controlling homogenizer rotating speed to be 10000-20000rpm/min, by the mixture thing point obtained by step 6) Dissipate uniform；
8) after step 7) is well mixed, when being naturally cooling to 45 DEG C, preservative is added, continues mechanical agitation to well mixed； Speed of agitator is 100-500rpm/min；And stop stirring after naturally cooling to room temperature, discharging, produce facial treatment milk.
7. a kind of toner of the composition containing containing peach gum hydrolysate described in claim 1, it is characterised in that by quality hundred Divide than calculating, the content and composition of its raw material are as follows：
Described solubilizer is rilanit special；
Described rheology control agent is hydroxyethyl cellulose；
The mixture that described preservative forms for hydroxyphenyl methyl esters with hydroxyphenyl propyl ester, hydroxyphenyl methyl esters and hydroxyphenyl propyl ester Mass ratio is 2：1.
8. the preparation method of the toner described in claim 7, it is characterised in that comprise the following steps：
1) each raw material is weighed according to mass ratio；
2) remove ionized water to be added in a reaction vessel, start agitator, rheology control agent is added in reaction vessel, Rheology control agent add finish continue stir 15-20min it is standby；
3) essence, solubilizer and preservative Hybrid Heating are heated to 40~50 DEG C as oil phase and obtain oil phase；
4) composition containing peach gum hydrolysate is added in the deionized water of step 2) and be heated uniformly to as Aqueous dispersions 45~55 DEG C obtain aqueous phase；
5) aqueous phase obtained by step 4) is cooled to 40~48 DEG C, then the oil phase obtained by step 3) is added to obtained by step 4) In aqueous phase, while mixer is opened, it is 300-500rpm/min to control mixing speed, is disperseed, and mechanical agitation is equal to mixing It is even and naturally cool to and stop stirring after room temperature, discharging, produce toner.
9. purposes of the composition for containing peach gum hydrolysate as skin barrier renovation agent described in claim 1.
CN201710763385.0A 2017-08-30 2017-08-30 A kind of composition containing peach gum hydrolysate and its preparation method and application Pending CN107412073A (en)

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CN109394635A (en) * 2018-12-28 2019-03-01 上海应用技术大学 A kind of preparation method of Fructus Liquidambaris fruit extract and its application in cosmetics
CN110464691A (en) * 2018-05-10 2019-11-19 北京东方淼森生物科技有限公司 A kind of peach gum composition and its application
CN110511969A (en) * 2019-09-06 2019-11-29 上海应用技术大学 Natural peach gum fermentation prepares the method for peach gum extract and its applies in cosmetics
CN112386538A (en) * 2020-11-19 2021-02-23 广东轻工职业技术学院 Noni mouthwash and preparation process thereof
CN112494386A (en) * 2020-12-15 2021-03-16 上海应用技术大学 Preparation method and application of blue butterfly extract with blue light resisting component
CN114632038A (en) * 2022-02-17 2022-06-17 广州丸美生物科技有限公司 Whitening sunscreen skin care matrix and preparation method thereof, and cosmetic and preparation method thereof

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CN103599021A (en) * 2013-11-15 2014-02-26 上海应用技术学院 Roselle extract as well as preparation method thereof and application thereof in whitening skincare cosmetics
CN105943432A (en) * 2016-05-10 2016-09-21 杭州西顿生物科技有限公司 Peach gum moisturizing gel mask and preparation method thereof
CN106214579A (en) * 2016-08-31 2016-12-14 郑超 A kind of noni ferment Whitening sunscreen cream and preparation method thereof

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CN102372789A (en) * 2010-08-25 2012-03-14 上海辉文生物技术有限公司 Peach gum polysaccharide, its extractive, preparation method and application thereof
CN103599021A (en) * 2013-11-15 2014-02-26 上海应用技术学院 Roselle extract as well as preparation method thereof and application thereof in whitening skincare cosmetics
CN105943432A (en) * 2016-05-10 2016-09-21 杭州西顿生物科技有限公司 Peach gum moisturizing gel mask and preparation method thereof
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CN110464691A (en) * 2018-05-10 2019-11-19 北京东方淼森生物科技有限公司 A kind of peach gum composition and its application
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CN110511969A (en) * 2019-09-06 2019-11-29 上海应用技术大学 Natural peach gum fermentation prepares the method for peach gum extract and its applies in cosmetics
CN112386538A (en) * 2020-11-19 2021-02-23 广东轻工职业技术学院 Noni mouthwash and preparation process thereof
CN112494386A (en) * 2020-12-15 2021-03-16 上海应用技术大学 Preparation method and application of blue butterfly extract with blue light resisting component
CN114632038A (en) * 2022-02-17 2022-06-17 广州丸美生物科技有限公司 Whitening sunscreen skin care matrix and preparation method thereof, and cosmetic and preparation method thereof
CN114632038B (en) * 2022-02-17 2023-12-29 广州丸美生物科技有限公司 Whitening sun-screening skin care matrix and preparation method thereof, and cosmetics and preparation method thereof

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