CN107184752A - A kind of blood fat regulating capsule and preparation method thereof - Google Patents
A kind of blood fat regulating capsule and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of blood fat regulating capsule, it is made up of the component of following mass fraction：145~160g of radix bupleuri, 140~160g of the bighead atractylodes rhizome, 170~190g of Poria cocos, 145~165g of Radix Angelicae Sinensis, 220~230g of oriental wormwood, 145~155g of rhizoma alismatis, 3~5g of lotus leaf, 175~185g of hawthorn, 145~155g of barrenwort；The preparation method of above-mentioned blood fat regulating capsule is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering, filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, is sieved, is mixed, it is encapsulated, produce.Originally can harmonizing the liver and spleen, nourshing blood and promoting blood circulation, reducing blood lipid improves HDL, for hyperlipidemia, artery sclerosis, slow liver, gastrointestinal disorders, menoxenia etc., and clinic often receives good effect with it.In 4 years, shown by the use to 70 patients, the medicine can effectively treat hyperlipidemia, efficient up to 94.29%.
Description
Technical field
The present invention relates to a kind of blood fat regulating capsule and preparation method thereof, belong to Chinese medicine preparation technical field.
Background technology
Blood fat is the neutral fat (triglycerides and cholesterol) and lipoid (phosphatide, glycolipid, sterol, steroids) in blood plasma
General name, be widely present in human body.They are the basic metabolism required materials of life cells.It is, in general, that the master in blood fat
It is triglycerides and cholesterol to want composition, and wherein triglycerides participant energy i (in vivo) is metabolized, and cholesterol is then mainly used in closing
Into cell serous coat, steroid hormone and bile acid.Hyperlipidemia refers to T-CHOL in blood plasma, triglycerides, low-density lipoprotein
One or more of which level rise in white.It is the more typical disease of a class, in addition to caused by minority is due to systemic disease (after
Hair property hyperlipidemia), the overwhelming majority is because genetic defect (or being interacted with environmental factor) causes (primary hyperlipemia
Disease).The clinical manifestation of hyperlipidemia mainly includes two broad aspects：(1) lipid deposits caused xanthoma in intradermal；(2)
The atherosclerosis of lipid in the blood vessels caused by skin deposition, produces coronary heart disease and peripheral angiopathy etc..Due to hyperlipidemia
When the incidence of xanthoma and not very high, the occurrence and development of atherosclerosis are then needed for quite a long time, so many
Number hyperlipidemia patient has no any symptom and anomalous body is levyd now.And the hyperlipidemia of patient is then frequently in progress blood life
Change what is be found when examining.
The content of the invention
It is an object of the invention to provide a kind of blood fat regulating capsule and preparation method thereof, preferably to enter for hyperlipidemia
Row treatment.
To achieve these goals, technical scheme is as follows.
A kind of blood fat regulating capsule, is made up of the component of following mass fraction：145~160g of radix bupleuri, 140~160g of the bighead atractylodes rhizome, Fu
170~190g of Siberian cocklebur, 145~165g of Radix Angelicae Sinensis, 220~230g of oriental wormwood, 145~155g of rhizoma alismatis, 3~5g of lotus leaf, hawthorn 175~
185g, 145~155g of barrenwort；The preparation method of above-mentioned blood fat regulating capsule is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining
Seven taste decoctings are boiled twice, 1 hour every time, collecting decoction, and filtering, filtrate is condensed into thick paste, are mixed with above-mentioned fine powder, are dried, powder
Fine powder is broken into, is sieved, is mixed, it is encapsulated, produce.
Preferably, above-mentioned blood fat regulating capsule, is made up of the component of following mass fraction：Radix bupleuri 145g, bighead atractylodes rhizome 140g, Poria cocos
170g, Radix Angelicae Sinensis 145g, oriental wormwood 220g, rhizoma alismatis 145g, lotus leaf 3g, hawthorn 175g, barrenwort 145g；The preparation of above-mentioned blood fat regulating capsule
Method is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering,
Filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, sieves, and mixes, encapsulated, produces.
Preferably, above-mentioned blood fat regulating capsule, is made up of the component of following mass fraction：Radix bupleuri 150g, bighead atractylodes rhizome 150g, Poria cocos
180g, Radix Angelicae Sinensis 150g, oriental wormwood 225g, rhizoma alismatis 150g, lotus leaf 4g, hawthorn 180g, barrenwort 150g；The preparation of above-mentioned blood fat regulating capsule
Method is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering,
Filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, sieves, and mixes, encapsulated, produces.
Preferably, above-mentioned blood fat regulating capsule, is made up of the component of following mass fraction：Radix bupleuri 160g, bighead atractylodes rhizome 160g, Poria cocos
190g, Radix Angelicae Sinensis 165g, oriental wormwood 230g, rhizoma alismatis 155g, lotus leaf 5g, hawthorn 185g, barrenwort 155g；The preparation of above-mentioned blood fat regulating capsule
Method is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering,
Filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, sieves, and mixes, encapsulated, produces.
The herbal pharmacology of above-mentioned each component and effect are as follows：
(1) radix bupleuri：It is bitter in taste, be slightly cold, Return liver, gallbladder channel.Have with inducing diaphoresis, the effect of soothing the liver rising Yang.For cold, fever,
Fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, the prolapse of uterus, irregular menstruation.
(2) bighead atractylodes rhizome：With strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, antiabortive effect, for spleen eating less, abdominal distention diarrhea,
Phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.
(3) Poria cocos：It is sweet, light, it is mild-natured.The thoughts of returning home, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For oedema oliguria,
Phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
(4) Radix Angelicae Sinensis：With benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, anticancer, it is anti-ageing anti-old, immune the effect of.
(5) oriental wormwood：Oriental wormwood clearing heat and promoting diuresis；Removing jaundice.Cure mainly：Jaundice, difficult urination, wet sore itch, infectious jaundice type liver
Inflammation etc..Pharmaceutical research has cholagogic, and liver function protecting is antipyretic, anti-inflammatory, reducing blood lipid, decompression, the effect such as coronary dilatation.
(6) rhizoma alismatis：Cure mainly the diseases such as nephritic dropsy, pyelonephritis, enteritis diarrhea, difficult urination.
(7) lotus leaf：Delicate fragrance rise dissipate have effects that to clear away heart-fire relieving summer-heat, dissipate stasis of blood hemostasis, disappear wind clearing damp.
(8) hawthorn：Hawthorn contains plurality of active ingredients, and with cardiac stimulant, the expansion effect such as blood vessel and excitement, hawthorn is to dysentery
Bacillus has certain antibacterial action, and has the effect such as convergence, hypotensive and norcholesterol.
(9) barrenwort：Tonifying kidney and strengthening yang, dispelling wind and eliminating dampness.Control impotence not lift, dribbling urination, muscles and bones contraction is anxious, hemiplegia, waist
Knee is powerless, and arthralgia pain due to rheumatism, four limbs are meciless.
Originally can harmonizing the liver and spleen, nourshing blood and promoting blood circulation, reducing blood lipid, improve HDL, for hyperlipidemia, artery is hard
Change, slow liver, gastrointestinal disorders, menoxenia etc., clinic often receives good effect with it.In 4 years, pass through the use to 70 patients
Show, the medicine can effectively treat hyperlipidemia, efficient up to 94.29%.
The beneficial effects of the present invention will now be described with reference to clinical experimental data：
1st, general information：Inventor have collected 140 hyperlipidemia patients altogether between in March, -2017 in March, 2013, wherein,
20 years old~50 years old age, state of an illness half a year~1 year.It is randomly divided into：Treatment group 70, control group 70.The data such as two groups of ages without
Significant difference, with comparativity.
2nd, test method：(1) control group takes lipid-lowering medicine, takes to specifications.The course for the treatment of 30 days.(2) treatment group is oral
The present invention according to medicament made from specific embodiment 2, it is early, middle and late it is each once.The course for the treatment of 30 days.(3) criterion of therapeutical effect and treatment knot
Really：Criterion of therapeutical effect：Recovery from illness：The clinical symptoms of hyperlipidemia all disappear.Take a turn for the better：The clinical symptom relief of hyperlipidemia, the state of an illness
Controlled.It is invalid：No significant improvement or aggravated in clinical symptoms for hyperlipidemia.Calculate efficient to fully recover and take a turn for the better.Treatment
Statistical result is shown in Table 1.
1 two groups of comparitive studies of table
As can be seen here, hyperlipidemia can safely and effectively be treated using medicine made from the prescription of the present invention.
Toxicity test：
Powder during test drug in the embodiment of the present invention 2.Experimental animal is ICR kind small white mouses, and 18~22 grams of body weight is female
Hero half and half, totally 40.Test method is, after fasting 12 hours, by 20 g kgs to mice lavage 4 months, long term toxicity examination
Test result to show, small white mouse body weight, Liver and kidney function, blood picture etc. and control group no significant difference, show that the security of the medicine is big,
Belong to nontoxic rank.
Embodiment
The embodiment of the present invention is described with reference to embodiment, to be better understood from the present invention.
Embodiment 1
Blood fat regulating capsule in the present embodiment, is made up of the component of following mass fraction：Radix bupleuri 145g, bighead atractylodes rhizome 140g, Poria cocos
170g, Radix Angelicae Sinensis 145g, oriental wormwood 220g, rhizoma alismatis 145g, lotus leaf 3g, hawthorn 175g, barrenwort 145g；The preparation of above-mentioned blood fat regulating capsule
Method is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering,
Filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, sieves, and mixes, encapsulated, produces.
Embodiment 2
Blood fat regulating capsule in the present embodiment, is made up of the component of following mass fraction：Radix bupleuri 150g, bighead atractylodes rhizome 150g, Poria cocos
180g, Radix Angelicae Sinensis 150g, oriental wormwood 225g, rhizoma alismatis 150g, lotus leaf 4g, hawthorn 180g, barrenwort 150g；The preparation of above-mentioned blood fat regulating capsule
Method is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering,
Filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, sieves, and mixes, encapsulated, produces.
Embodiment 3
Blood fat regulating capsule in the present embodiment, is made up of the component of following mass fraction：Radix bupleuri 160g, bighead atractylodes rhizome 160g, Poria cocos
190g, Radix Angelicae Sinensis 165g, oriental wormwood 230g, rhizoma alismatis 155g, lotus leaf 5g, hawthorn 185g, barrenwort 155g；The preparation of above-mentioned blood fat regulating capsule
Method is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled twice, 1 hour every time, collecting decoction, filtering,
Filtrate is condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, sieves, and mixes, encapsulated, produces.
Described above is the preferred embodiment of the present invention, it is noted that for those skilled in the art
For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as
Protection scope of the present invention.
Claims (4)
1. a kind of blood fat regulating capsule, it is characterised in that：It is made up of the component of following mass fraction：145~160g of radix bupleuri, the bighead atractylodes rhizome 140
~160g, 170~190g of Poria cocos, 145~165g of Radix Angelicae Sinensis, 220~230g of oriental wormwood, 145~155g of rhizoma alismatis, 3~5g of lotus leaf, hawthorn
175~185g, 145~155g of barrenwort；The preparation method of above-mentioned blood fat regulating capsule is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, mistake
Sieve, remaining seven taste decocting are boiled twice, 1 hour every time, collecting decoction, and filtering, filtrate is condensed into thick paste, are mixed with above-mentioned fine powder,
Fine powder is dry, pulverize into, is sieved, is mixed, it is encapsulated, produce.
2. blood fat regulating capsule according to claim 1, it is characterised in that：Above-mentioned blood fat regulating capsule, by the group of following mass fraction
It is grouped into：Radix bupleuri 145g, bighead atractylodes rhizome 140g, Poria cocos 170g, Radix Angelicae Sinensis 145g, oriental wormwood 220g, rhizoma alismatis 145g, lotus leaf 3g, hawthorn 175g,
Barrenwort 145g；The preparation method of above-mentioned blood fat regulating capsule is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled
Twice, every time 1 hour, collecting decoction, filtering, filtrate was condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, mistake
Sieve, is mixed, encapsulated, is produced.
3. blood fat regulating capsule according to claim 1, it is characterised in that：Above-mentioned blood fat regulating capsule, by the group of following mass fraction
It is grouped into：Radix bupleuri 150g, bighead atractylodes rhizome 150g, Poria cocos 180g, Radix Angelicae Sinensis 150g, oriental wormwood 225g, rhizoma alismatis 150g, lotus leaf 4g, hawthorn 180g,
Barrenwort 150g；The preparation method of above-mentioned blood fat regulating capsule is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled
Twice, every time 1 hour, collecting decoction, filtering, filtrate was condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, mistake
Sieve, is mixed, encapsulated, is produced.
4. blood fat regulating capsule according to claim 1, it is characterised in that：Above-mentioned blood fat regulating capsule, by the group of following mass fraction
It is grouped into：Radix bupleuri 160g, bighead atractylodes rhizome 160g, Poria cocos 190g, Radix Angelicae Sinensis 165g, oriental wormwood 230g, rhizoma alismatis 155g, lotus leaf 5g, hawthorn 185g,
Barrenwort 155g；The preparation method of above-mentioned blood fat regulating capsule is：The bighead atractylodes rhizome, Poria cocos are ground into fine powder, sieved, remaining seven taste decocting is boiled
Twice, every time 1 hour, collecting decoction, filtering, filtrate was condensed into thick paste, is mixed with above-mentioned fine powder, dry, pulverize into fine powder, mistake
Sieve, is mixed, encapsulated, is produced.
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| CN113144150A (en) * | 2021-06-16 | 2021-07-23 | 朱军龙 | Traditional Chinese medicine for reducing blood fat and preparation method thereof |
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