CN102488781A - Traditional Chinese medicine composition for treating wind-damp-cold arthralgia - Google Patents
Traditional Chinese medicine composition for treating wind-damp-cold arthralgia Download PDFInfo
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- CN102488781A CN102488781A CN2011104220581A CN201110422058A CN102488781A CN 102488781 A CN102488781 A CN 102488781A CN 2011104220581 A CN2011104220581 A CN 2011104220581A CN 201110422058 A CN201110422058 A CN 201110422058A CN 102488781 A CN102488781 A CN 102488781A
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Abstract
The invention relates to an orally administrated traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for treating wind-damp-cold arthralgia. The traditional Chinese medicine composition is prepared by raw materials of traditional Chinese medicine including, by weight, from 15 to 20 parts of scorpia, from 1 to 3 parts of musk, from 15 to 30 parts of notopterygium root, from 15 to 20 parts of radices sileris, from 10 to 20 parts of the root of bidentate achyranthes, from 10 to 20 parts of processed frankincense, from 10 to 20 parts of myrrh, from 10 to 30 parts of the rhizome of Chinese atractylode, from 10 to 30 parts of rehmannia glutinosa, from 10 to 20 parts of Chinese angelica, from 20 to 50 parts of eucommia ulmoides and from 30 to 50 parts of fructus psoraleae. The traditional Chinese medicine composition has effects of analgesia, subsidence of a swelling and blood circulation promotion, is few in side effects after being taken by a patient, and is effective in treatment.
Description
Technical field
The present invention relates to a kind of oral Chinese medicine preparation, particularly a kind of Chinese medicine composition of treating cold rheumatoid joint pain.
Background technology
Cold rheumatoid joint pain (abbreviation rheumatic arthralgia) is meant that the muscle, the arthralgia that cause behind human feeling's wind-cold damp pathogen are the main disease that shows.The Therapeutic Method of cold rheumatoid joint pain has partial insulation, physical therapy, acupuncture, massage, and these several kinds of Therapeutic Method help rapid recovery, slow down pain, and this can not dig up the roots.The patient more of a specified duration for stadium will carry out Drug therapy, behind the western medicine side effect of most Western medicine obvious, and can not thoroughly dig up the roots; Physical therapy need be adhered to for a long time, can not interrupt.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of treating cold rheumatoid joint pain, it has the effect of analgesia, detumescence, blood circulation promoting, and side effect is little, evident in efficacy after taking.
Technical scheme of the present invention is: a kind of Chinese medicine composition of treating cold rheumatoid joint pain is characterized in that: the raw material of Chinese medicine medicine by following weight parts is formulated: Scorpio 15-20 part, Moschus 1-3 part, Rhizoma Et Radix Notopterygii 15-30 part, windproof 15-20 part, Radix Achyranthis Bidentatae 10-20 part, Olibanum (processed) 10-20 part, Myrrha 10-20 part, Rhizoma Atractylodis 10-30 part, Radix Rehmanniae Preparata 10-30 part, Radix Angelicae Sinensis 10-20 part, Cortex Eucommiae 20-50 part, Fructus Psoraleae 30-50 part.
Said a kind of weight portion of treating the Chinese medicine composition of cold rheumatoid joint pain is: 18 parts of Scorpios, 2 parts in Moschus, 25 parts of Rhizoma Et Radix Notopterygiis, windproof 18 parts, 15 parts of Radix Achyranthis Bidentataes, 15 parts of Olibanum (processed)s, 15 parts of Myrrhas, 20 parts of Rhizoma Atractylodis, 20 parts in Radix Rehmanniae Preparata, 15 parts of Radix Angelicae Sinensis, 30 parts of the Cortexs Eucommiae, 40 parts of Fructus Psoraleaes.
Said a kind of weight portion of treating the Chinese medicine composition of cold rheumatoid joint pain is: 15 parts of Scorpios, 1 part in Moschus, 15 parts of Rhizoma Et Radix Notopterygiis, windproof 15 parts, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Olibanum (processed)s, 10 parts of Myrrhas, 10 parts of Rhizoma Atractylodis, 10 parts in Radix Rehmanniae Preparata, 10 parts of Radix Angelicae Sinensis, 20 parts of the Cortexs Eucommiae, 30 parts of Fructus Psoraleaes.
Said a kind of weight portion of treating the Chinese medicine composition of cold rheumatoid joint pain is: 20 parts of Scorpios, 3 parts in Moschus, 30 parts of Rhizoma Et Radix Notopterygiis, windproof 20 parts, 20 parts of Radix Achyranthis Bidentataes, 20 parts of Olibanum (processed)s, 20 parts of Myrrhas, 30 parts of Rhizoma Atractylodis, 30 parts in Radix Rehmanniae Preparata, 20 parts of Radix Angelicae Sinensis, 50 parts of the Cortexs Eucommiae, 50 parts of Fructus Psoraleaes.
The present invention also provides the method for preparing of above-mentioned Chinese medicine composition, comprises the steps:
1) crude drug of getting in the above-mentioned raw materials carries out roguing respectively, and clean, dry, subsequent use;
2), in the above raw material, Scorpio, Moschus powder are broken into 100 order fine powders, subsequent use;
3), Rhizoma Et Radix Notopterygii is boiled 1 hour after-filtration separately, extract volatile oil, subsequent use;
4), all the other crude drug are mixed, and the decocting that adds 10 times of amounts boils, and decocts 2 hours after-filtration, filtrate for later use;
5) decocting that the medicinal residues that, step 4) obtained add 8 times of amounts again boils 2 hours after-filtration, filtrate for later use;
6), with step 3), 4), 5) filtrating that obtains mixing be incorporated in 60 ℃ and be evaporated to the thick paste that relative density is 1.20-1.25, and be subsequent use;
7), with step 2) thick paste mix homogeneously that the fine powder that obtains and step 6) obtain, drying is ground into fine powder, processes described Chinese medicine composition.
This pharmacy optimization be capsule, every of specification contains active ingredient 0.5 g, oral one time 4,3 times on the 1st, serveing on for 4 weeks was 1 course of treatment, best with the heat wine effect of taking after mixing it with water.
Characteristics of the present invention are: characteristics of the present invention are reasonable recipe, meet theory of Chinese medical science: Scorpio acrid in the mouth, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; The hot temperature of Moschus, the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving; Rhizoma Et Radix Notopterygii is arduous, the exterior cold of loosing; Wind-damp dispelling; Sharp joint; Pain relieving; Windproof sweet in the mouth, expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion; The Radix Achyranthis Bidentatae bitter in the mouth, soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Olibanum is arduous, regulating qi and activating blood, and analgesic therapy chases after poison; Myrrha is arduous, the blood blood stasis removing that looses, subduing swelling and relieving pain; Rhizoma Atractylodis are arduous, and are drying damp and strengthening spleen, expelling wind and cold; The Radix Rehmanniae Preparata sweet in the mouth, the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; The hot temperature of Radix Angelicae Sinensis is enriched blood and is invigorated blood circulation; The hot temperature of the Cortex Eucommiae, invigorating the liver and kidney, bone and muscle strengthening; Fructus Psoraleae is arduous, reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha; Said medicine has the effect of blood circulation promoting and blood stasis dispelling, analgesia, detumescence.
The specific embodiment
Through the specific embodiment that provides the present invention is described clearly further below, but not as to qualification of the present invention.
Embodiment 1
Said a kind of weight portion of treating the Chinese medicine composition of cold rheumatoid joint pain is: 18 parts of Scorpios, 2 parts in Moschus, 25 parts of Rhizoma Et Radix Notopterygiis, windproof 18 parts, 15 parts of Radix Achyranthis Bidentataes, 15 parts of Olibanum (processed)s, 15 parts of Myrrhas, 20 parts of Rhizoma Atractylodis, 20 parts in Radix Rehmanniae Preparata, 15 parts of Radix Angelicae Sinensis, 30 parts of the Cortexs Eucommiae, 40 parts of Fructus Psoraleaes.
The present invention also provides the method for preparing of above-mentioned Chinese medicine composition, comprises the steps:
1) crude drug of getting in the above-mentioned raw materials carries out roguing respectively, and clean, dry, subsequent use;
2), in the above raw material, Scorpio, Moschus powder are broken into 100 order fine powders, subsequent use;
3), Rhizoma Et Radix Notopterygii is boiled 1 hour after-filtration separately, extract volatile oil, subsequent use;
4), all the other crude drug are mixed, and the decocting that adds 10 times of amounts boils, and decocts 2 hours after-filtration, filtrate for later use;
5) decocting that the medicinal residues that, step 4) obtained add 8 times of amounts again boils 2 hours after-filtration, filtrate for later use;
6), with step 3), 4), 5) filtrating that obtains mixing be incorporated in 60 ℃ and be evaporated to the thick paste that relative density is 1.20-1.25, and be subsequent use;
7), with step 2) thick paste mix homogeneously that the fine powder that obtains and step 6) obtain, drying is ground into fine powder, processes described Chinese medicine composition.
Embodiment 2
Said a kind of weight portion of treating the Chinese medicine composition of cold rheumatoid joint pain is: 15 parts of Scorpios, 1 part in Moschus, 15 parts of Rhizoma Et Radix Notopterygiis, windproof 15 parts, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Olibanum (processed)s, 10 parts of Myrrhas, 10 parts of Rhizoma Atractylodis, 10 parts in Radix Rehmanniae Preparata, 10 parts of Radix Angelicae Sinensis, 20 parts of the Cortexs Eucommiae, 30 parts of Fructus Psoraleaes.Preparation and method for using are with embodiment 1.
Embodiment 3
Said a kind of weight portion of treating the Chinese medicine composition of cold rheumatoid joint pain is: 20 parts of Scorpios, 3 parts in Moschus, 30 parts of Rhizoma Et Radix Notopterygiis, windproof 20 parts, 20 parts of Radix Achyranthis Bidentataes, 20 parts of Olibanum (processed)s, 20 parts of Myrrhas, 30 parts of Rhizoma Atractylodis, 30 parts in Radix Rehmanniae Preparata, 20 parts of Radix Angelicae Sinensis, 50 parts of the Cortexs Eucommiae, 50 parts of Fructus Psoraleaes.
Preparation and method for using are with embodiment 1.
The umber of Chinese medicine component can be got gram (g), kilogram (kg), ton (t).
In order to show the therapeutic effect of medicine of the present invention, the present invention has carried out clinical trial.
One, object and method
Select case by following diagnostic criteria:
1, arthralgia, especially the gonalgia is obvious, and is relevant with climate change;
2, the joint does not have tangible redness, distortion;
3, morning, deadlock was not obvious;
4, the joint does not have tenderness;
5, erythrocyte sedimentation rate is higher or normal, and all negative or anti-O of anti-O, RF is higher;
6, X-ray examination is no abnormal.
The clinical trial of a kind of Chinese medicine composition of treating cold rheumatoid joint pain proposed by the invention is following: select age 28-55 year patient 160 examples, wherein male 90 examples, women 70 examples, 40 years old mean age, the course of disease 7 days-20 years, average course of disease 8 years.The patient did not accept the other drug treatment before this treatment.30 days is a course of treatment, carries out symptom score after 2 courses of treatment.120 routine patients are divided into 4 groups at random, i.e. treatment group 1, treatment group 2, contrast A group, contrast B group, and treatment group 1 adopts medicine of the present invention; Treatment group 2, material component and treatment group 1 that treatment group 2 adopts are the same materials components, and production technology is different, and treatment group 2 is first together the mixing together of all material components to be brewed into paste medicine; Contrast A group is regularly taken SHEXIANG ZHUIFENG GAO; Contrast B group is with nine credit joint physiotherapy table; Be careful in one's diet during this time and have a rest.
All carry out clinical examination before 4 groups of patient treatments, comprise system's health check-up, joint swelling index detection, the detection of articular pain index etc.Lab testing comprise blood, routine urinalysis, liver, renal function, ESR, RF,
ASO, serum IgG, IgA, IgM, Chest X-rays and joint x mating plate, some cases has been measured serum selenium content.
1 of the oral Chinese medicine composition by the present invention preparation of treatment group 2 times on the 1st.2 oral same materials are organized in treatment, 2 of production technology different drug, and 2 times on the one, the oral SHEXIANG ZHUIFENG GAO of control group A, 3 times on the 1st, matched group B is with nine credit joint physiotherapy table.It was 1 course of treatment all with 30 days.In reality
Test viewing duration and stop to use other rheumatism Chinese medicine and western medicine.The side effect of treatment beginning back record paresthesia alleviateding time and appearance.Treatment finishes the above-mentioned each item of back check.
Two. observation item and efficacy assessment standard
Below six as the treatment efficiency indexs: (1) is no weak; (2) no arthralgia; The joint did not have pain yet when (3) movable back and meteorology changed, local no tenderness; (4) arthroncus disappears; (5) ESR < 30mm/>h (woman), ESR < 2 Omm/>h (man); (6) ASO, RF are normal basically.
Produce effects: meet in above-listed 6 at least 5, and continue person more than two months;
Effectively: meet 4 in above-mentioned 6 and also continue person more than two months.
Invalid: 1～2 person of meeting is only arranged in above-mentioned 6, or with the treatment before no change.
Three. the result
(1) evaluate according to above criterion of therapeutical effect, it is 9 7.5 5% that total 1 effective percentage is organized in treatment, and the effective percentage of treatment group 2 is 7.5 5%, and the control group A total effective rate is 87.30%.Matched group B total effective rate is 87.30% liang of group curative effect difference highly significant (P < O.01), sees table l.
Therapeutic outcome:
Treat after 7 days, therapeutic effect is relatively seen table 1.
Table 1 pharmaceutical treatment of the present invention is the effect comparison after 7 days
| Group | Number | Produce effects (%) | Effectively (%) | Invalid (%) | 10 days effective percentage |
| Treatment group 1 | 40 | 20（50） | 10（25） | 10（25） | 75% |
| Treatment group 2 | 40 | 15（37.5） | 13（32.5） | 12（30） | 70% |
| Contrast A group | 40 | 13（32.5） | 14（35 | 13（32.5） | 67.5% |
| Contrast B group | 40 | 14（35） | 11（27.5） | 15（37.5） | 62.5% |
Each item index comparison before and after table 2 treatment group and the matched group
Compare with matched group (P 0.05).
All checked joint X-ray sheet for four groups, no special.
Visible by table 1; The effect of the treatment group 1 of the Chinese medicine that use the present invention is made is apparently higher than treatment group 2; Explain that production technology has very big influence to therapeutic effect, the effect of treatment group 1 is apparently higher than contrast A group and contrast B group, and symptom takes a turn for the better apparently higher than with SHEXIANG ZHUIFENG GAO and nine credit joint physiotherapy table; The therapeutic effect that shows the capsule that use the present invention is made is good, and obvious effective rate is high.
Claims (5)
1. Chinese medicine composition of treating cold rheumatoid joint pain, it is characterized in that: the raw material of Chinese medicine medicine by following weight parts is formulated: Scorpio 15-20 part, Moschus 1-3 part, Rhizoma Et Radix Notopterygii 15-30 part, windproof 15-20 part, Radix Achyranthis Bidentatae 10-20 part, Olibanum (processed) 10-20 part, Myrrha 10-20 part, Rhizoma Atractylodis 10-30 part, Radix Rehmanniae Preparata 10-30 part, Radix Angelicae Sinensis 10-20 part, Cortex Eucommiae 20-50 part, Fructus Psoraleae 30-50 part.
2. according to the said a kind of Chinese medicine composition of treating cold rheumatoid joint pain of claim 1, it is characterized in that: its weight portion is: 18 parts of Scorpios, 2 parts in Moschus, 25 parts of Rhizoma Et Radix Notopterygiis, windproof 18 parts, 15 parts of Radix Achyranthis Bidentataes, 15 parts of Olibanum (processed)s, 15 parts of Myrrhas, 20 parts of Rhizoma Atractylodis, 20 parts in Radix Rehmanniae Preparata, 15 parts of Radix Angelicae Sinensis, 30 parts of the Cortexs Eucommiae, 40 parts of Fructus Psoraleaes.
3. according to the said a kind of Chinese medicine composition of treating cold rheumatoid joint pain of claim 1, it is characterized in that: its weight portion is: 15 parts of Scorpios, 1 part in Moschus, 15 parts of Rhizoma Et Radix Notopterygiis, windproof 15 parts, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Olibanum (processed)s, 10 parts of Myrrhas, 10 parts of Rhizoma Atractylodis, 10 parts in Radix Rehmanniae Preparata, 10 parts of Radix Angelicae Sinensis, 20 parts of the Cortexs Eucommiae, 30 parts of Fructus Psoraleaes.
4. according to the said a kind of Chinese medicine composition of treating cold rheumatoid joint pain of claim 1, it is characterized in that: its weight portion is: 20 parts of Scorpios, 3 parts in Moschus, 30 parts of Rhizoma Et Radix Notopterygiis, windproof 20 parts, 20 parts of Radix Achyranthis Bidentataes, 20 parts of Olibanum (processed)s, 20 parts of Myrrhas, 30 parts of Rhizoma Atractylodis, 30 parts in Radix Rehmanniae Preparata, 20 parts of Radix Angelicae Sinensis, 50 parts of the Cortexs Eucommiae, 50 parts of Fructus Psoraleaes.
5. according to the described a kind of method for preparing of treating the Chinese medicine composition of cold rheumatoid joint pain of claim 1-4, comprise the steps:
1) crude drug of getting in the above-mentioned raw materials carries out roguing respectively, and clean, dry, subsequent use;
2), in the above raw material, Scorpio, Moschus powder are broken into 100 order fine powders, subsequent use;
3), Rhizoma Et Radix Notopterygii is boiled 1 hour after-filtration separately, extract volatile oil, subsequent use;
4), all the other crude drug are mixed, and the decocting that adds 10 times of amounts boils, and decocts 2 hours after-filtration, filtrate for later use;
5) decocting that the medicinal residues that, step 4) obtained add 8 times of amounts again boils 2 hours after-filtration, filtrate for later use;
6), with step 3), 4), 5) filtrating that obtains mixing be incorporated in 60 ℃ and be evaporated to the thick paste that relative density is 1.20-1.25, and be subsequent use;
7), with step 2) thick paste mix homogeneously that the fine powder that obtains and step 6) obtain, drying is ground into fine powder, processes described Chinese medicine composition.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011104220581A CN102488781A (en) | 2010-12-16 | 2011-12-16 | Traditional Chinese medicine composition for treating wind-damp-cold arthralgia |
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| CN201010591925XA CN102028813A (en) | 2010-12-16 | 2010-12-16 | Chinese herbal composition for treating wind-damp-cold arthralgia |
| CN201010591925.X | 2010-12-16 | ||
| CN2011104220581A CN102488781A (en) | 2010-12-16 | 2011-12-16 | Traditional Chinese medicine composition for treating wind-damp-cold arthralgia |
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| CN2011104220581A Pending CN102488781A (en) | 2010-12-16 | 2011-12-16 | Traditional Chinese medicine composition for treating wind-damp-cold arthralgia |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105362986A (en) * | 2015-11-16 | 2016-03-02 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for treating rheumatism cold disease |
| CN105362881A (en) * | 2015-11-16 | 2016-03-02 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for wind-dampness cold type of arthralgia and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115501302A (en) * | 2022-09-30 | 2022-12-23 | 刘建设 | Traditional Chinese medicine external application membrane powder |
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2010
- 2010-12-16 CN CN201010591925XA patent/CN102028813A/en active Pending
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- 2011-12-16 CN CN2011104220581A patent/CN102488781A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105362986A (en) * | 2015-11-16 | 2016-03-02 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for treating rheumatism cold disease |
| CN105362881A (en) * | 2015-11-16 | 2016-03-02 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for wind-dampness cold type of arthralgia and preparation method thereof |
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| CN102028813A (en) | 2011-04-27 |
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Application publication date: 20120613 |