CN107007538A - A kind of oral care composition and application containing marine element, and the toothpaste containing marine element - Google Patents
A kind of oral care composition and application containing marine element, and the toothpaste containing marine element Download PDFInfo
- Publication number
- CN107007538A CN107007538A CN201710123859.5A CN201710123859A CN107007538A CN 107007538 A CN107007538 A CN 107007538A CN 201710123859 A CN201710123859 A CN 201710123859A CN 107007538 A CN107007538 A CN 107007538A
- Authority
- CN
- China
- Prior art keywords
- extract
- toothpaste
- care composition
- oral care
- marine element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
The present invention discloses a kind of oral care composition containing marine element and application, and the toothpaste containing marine element, what the lotion thickener and sea salt that algae extract, xanthans and the carrageenan that the oral care composition for containing marine element is made up of spirulina extract, Crithmum maritimum extract or bladder-wrack extract are constituted were constituted.The oral care composition of the present invention realizes spirulina extract, the synergy of three kinds of algae extracts of Crithmum maritimum extract and bladder-wrack extract, it is common that useful effect is carried out to oral problems such as oral peculiar smell, bacterial plaque and tooth stains, and lotion thickener ensure that the stability of product, sea salt can also realize cleaning, bactericidal action to oral cavity.The toothpaste that oral care composition of the invention containing marine element is prepared into can remove oral peculiar smell, reduce bacterial plaque, mitigate tooth stain and protection gums healthy, be used for a long time notable to the nursing efficacy of oral cavity, especially tooth.
Description
Technical field
The present invention relates to oral care techniques field, more particularly to a kind of oral care composition containing marine element and should
With, and the toothpaste prepared by the oral care composition containing marine element.
Background technology
Sea-plant is rich in compositions such as polysaccharide, vitamin and ocean mineral, with traditional plant extract and artificial synthesized original
Material compared to it is more natural, more healthy, be more easy to absorption；The a variety of biologies in ocean have stronger antibiotic property, utilize marine organisms bacteriostasis property
Being developed also turns into popular industry at present for drug research.Marine resources because of its distinctive both effectiveness, natural sex, reproducibility
In cosmetics, health products, pharmaceutically it is used widely, but is started late in the research of oral cavity industry, application level is relatively limited to.
Marine element is less in the application pertinent literature report of oral care product, and Sun Fusong and Shao Yuhang researchs are reported
Marine organisms glycosaminoglycan (AHA) and application of the natural traditional Chinese medicine extract in toothpaste, AHA are added in toothpaste, and empirical tests should
Toothpaste has very strong inhibiting bacteria and diminishing inflammation function, to gingivitis, especially has significant curative effect and prevention effect to canker sore, and
Chinese herbal medicine extract is overcome as the influence lotion outward appearance brought during active matter by color and luster, smell, the problem of mouthfeel.
The Novel dental nursing product containing marine element is researched and developed, more marine resources are applied to oral cavity industry, hair
Wave marine resources has important researching value and the wide market space in the advantage of oral cavity industry.
The content of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide it is a kind of rich in marine element, with cleaning mouth
The characteristics of chamber, mitigation tooth stain, functions of whitening teeth and fresh breath, the oral care composition of gums healthy can be protected.
It is another object of the present invention to provide application of the above-mentioned oral care composition in toothpaste is prepared.
Prepared it is another object of the present invention to provide a kind of by above-mentioned oral care composition containing marine element
Toothpaste.
The above-mentioned purpose of the present invention is achieved by following scheme：
A kind of oral care composition containing marine element, said composition is made up of each component of following parts by weight：
0.01~2 part of algae extract；
0.1~2 part of lotion thickener；
0.1~5 part of sea salt.
Above-mentioned algae extract be in spirulina extract, bladder-wrack extract or Crithmum maritimum extract any one or
The mixing of two or more arbitrary proportion；When algae extract is using spirulina extract, bladder-wrack extract and extra large fennel
During the mixing of fragrant extract three, the weight of spirulina extract, bladder-wrack extract and Crithmum maritimum extract in the mixture
Than being preferably (0.05~1):(0.5~1):1.
Above-mentioned spirulina extract can realize the present invention using commercially available any spirulina extract, it is preferred to use
Spirulina extract of the protein content more than 70%；Above-mentioned bladder-wrack extract is carried using commercially available any bladder-wrack
Take thing can realize the present invention, it is preferred to use bladder-wrack extract of the content of mineral substances more than 15%；Above-mentioned Crithmum maritimum is extracted
Thing can realize the present invention using commercially available any Crithmum maritimum extract.
The present inventor has found by studying, and thickener is the key reason of leading toothpaste stability, therefore toothpaste thickening
The selection of agent, it should be to have good viscosity and thixotropy, it is easily scattered to be swelled, there is preferable antienzyme salt tolerance, brought to essence
Preferably saturating hair property, the color and luster of lotion is not influenceed；For algae extract of preferably arranging in pairs or groups, and ensure the excellent of toothpaste stability
Good, the present inventor has carried out conceptual design, screening to thickener and optimized, final to determine that lotion thickener of the present invention is pitched using angle
The part by weight of carrageenan and xanthans is 0.1 in the mixture of dish glue and xanthans, and the mixture:1~1:1；It is preferred that
0.5:1~1:1.Xanthans has excellent thickening property and suspension, and antienzyme salt tolerance is strong, with good pseudoplastic behavior, to essence
Stability and release property have good release performance；Carrageenan has the fundamental characteristics of soluble dietary fiber, the cream being made
Body has excellent extrudability, fragrance release property and easy rinse；The present invention is compounded from xanthans and carrageenan, both have compared with
Good synergy, can improve the glossiness and water-retaining property of lotion.
A kind of above-mentioned oral care composition containing marine element, said composition is preferably each group by following parts by weight
It is grouped into：
0.1~1 part of algae extract；
0.5~1.5 part of lotion thickener；
0.3~3 part of sea salt.
A kind of above-mentioned oral care composition containing marine element can arrange in pairs or groups and be subjected on oral cavity well-known in the art
Carrier component be prepared into toothpaste；The carrier component is antiseptic, ascoxal, (prevention bacterial plaque sticks to tooth to antitack agent
Enamel surfaces), polyphenoils (such as Co-Q10), caries preventive agent, desensitizer (such as potassium nitrate, potassium tartrate, potassium citrate or chlorination
Strontium), brightening agent, tartar control agents, periodontal actives, chlorophyll compound, abrasive material, breath freshening controlling agent (such as gluconic acid
Zinc, zinc citrate, zinc chloride), saliva stimulant (such as citric acid, lactic acid, malic acid), viscosity modifier, diluent, surface
Active material, emulsifying agent and foam modifier, pH adjusting agent, abrasive material, NMF, softening agent, mouth feel modifying agents, sweetener, tune
The component well known by persons skilled in the art suitable for toothpaste such as taste agent, colouring agent or preservative, and specific thing in carrier component
The selection of matter is the material that selection is mutually compatible with the oral care composition containing marine element of the present invention, cooperate with.
Oral care composition of the invention containing marine element is when other carrier components of arranging in pairs or groups are prepared into toothpaste, the oral cavity
The consumption of care composition is the 0.5%~3% of toothpaste gross weight, preferably 2%~3%.
The present invention also provides a kind of toothpaste containing marine element, and the toothpaste is by a kind of above-mentioned oral cavity shield containing marine element
Reason composition other carrier components of arranging in pairs or groups are prepared, and the formula of the toothpaste is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
What the above-mentioned oral care composition containing marine element was made up of each component of following parts by weight：
0.1~1 part of algae extract；
0.5~1.5 part of lotion thickener；
0.3~3 part of sea salt.
Above-mentioned algae extract be in spirulina extract, bladder-wrack extract or Crithmum maritimum extract any one or
The mixing of two or more arbitrary proportion；When algae extract is using spirulina extract, bladder-wrack extract and extra large fennel
During the mixing of fragrant extract three, the weight of spirulina extract, bladder-wrack extract and Crithmum maritimum extract in the mixture
Than being preferably (0.05~1):(0.5~1):1.
Above-mentioned lotion thickener is carrageenan and xanthans according to 0.5:1~1:1 weight than mixing.
Above-mentioned PEG-400 is polyvinyl alcohol 400.
The above-mentioned toothpaste containing marine element, its preparation method comprises the following steps：
Step 1
By sea salt, Crithmum maritimum extract, bladder-wrack extract, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate
It is dissolved in deionized water, aqueous phase is made in stirring and dissolving；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, and laruyl alcohol sodium sulfovinate, spirulina extract and essence are added after stirring 20min,
Mixing speed is adjusted to 1500r/min, stirring 15min and then prepares the toothpaste containing marine element of the present invention.
The present invention a kind of toothpaste containing marine element clinical tests prove that, it can effectively remove oral peculiar smell, subtract
Few bacterial plaque, mitigates tooth stain, protects gums healthy.
Compared with prior art, the present invention has the advantages that：
1. the research that algae extract is used for oral care by prior art is few, and by spirulina extract, bladder-wrack
Extract, Crithmum maritimum extract are used for the research of oral care there is not yet any report；The present inventor is had found by studying：Spiral
Algae has very high nutritive value, has good effect to gastric ulcer and suppression cancer cell of oral cavity, Crithmum maritimum can provide Gao Ying
Material and anti-inflammatory efficacy are supported, bladder-wrack has certain nourishing, moisture-keeping function to oral cavity；And the oral care composition of the present invention, it is first
The secondary extract by spirulina, Crithmum maritimum and bladder-wrack these three algae is introduced into oral care product, passes through rational consumption
Proportioning with so that spirulina extract, Crithmum maritimum extract and bladder-wrack extract can act synergistically, jointly different to oral cavity
The oral problems such as taste, bacterial plaque and tooth stain carry out useful effect；
2. the oral care composition of the present invention is compounded as lotion thickener using carrageenan and xanthans, not only can
Enough and spirulina extract, Crithmum maritimum extract and bladder-wrack extract realize compatibility, are conducive to these three algae extract work(
The performance of effect, and made toothpaste light is strong without glutinous greasy；
3. the sea salt that the oral care composition of the present invention is used, it, can deep layer containing abundant mineral matter and trace element
Oral cavity, bactericidal antiphlogistic are cleaned, reduction bacterial plaque, the effect of fresh breath is reached；
Oral peculiar smell is removed, bacterial plaque is reduced, mitigates tooth stain, protection gum 4. the oral care composition of the present invention has
Effect of health, the conventional toothpaste assistant agent of collocation is prepared into after tooth paste product, and the nursing to oral cavity, especially tooth is used for a long time
Effect is notable.
Embodiment
The present invention is further described through with reference to specific embodiment, but specific embodiment is not appointed to the present invention
What is limited.
Embodiment 1
The toothpaste of the present embodiment, its formula is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
The present embodiment toothpaste is to be prepared by the following method：
Step 1
Sea salt, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate are dissolved in deionized water, stirring and dissolving system
Into aqueous phase；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, adds laruyl alcohol sodium sulfovinate and essence after stirring 20min, mixing speed is adjusted
To 1500r/min, stirring 15min then prepares the toothpaste of the present embodiment.
Embodiment 2
The toothpaste of the present embodiment, its formula is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
The above-mentioned oral care composition containing marine element, is made up of each component of following parts by weight：
The present embodiment toothpaste is to be prepared by the following method：
Step 1
Sea salt, Crithmum maritimum extract, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate are dissolved in deionized water
In, aqueous phase is made in stirring and dissolving；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, adds laruyl alcohol sodium sulfovinate and essence after stirring 20min, mixing speed is adjusted
To 1500r/min, stirring 15min then prepares the toothpaste of the present embodiment.
Embodiment 3
The toothpaste of the present embodiment, its formula is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
The present embodiment toothpaste is to be prepared by the following method：
Step 1
Sea salt, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate are dissolved in deionized water, stirring and dissolving system
Into aqueous phase；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, and laruyl alcohol sodium sulfovinate, spirulina extract and essence are added after stirring 20min,
Mixing speed is adjusted to 1500r/min, stirring 15min and then prepares the toothpaste of the present embodiment.
Embodiment 4
The toothpaste of the present embodiment, its formula is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
The present embodiment toothpaste is to be prepared by the following method：
Step 1
Sea salt, bladder-wrack extract, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate are dissolved in deionized water
In, aqueous phase is made in stirring and dissolving；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, and spirulina extract, laruyl alcohol sodium sulfovinate and essence are added after stirring 20min,
Mixing speed is adjusted to 1500r/min, stirring 15min and then prepares the toothpaste of the present embodiment.
Embodiment 5
The toothpaste of the present embodiment, its formula is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
The present embodiment toothpaste is to be prepared by the following method：
Step 1
By sea salt, bladder-wrack extract, Crithmum maritimum extract, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate
It is dissolved in deionized water, aqueous phase is made in stirring and dissolving；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, adds laruyl alcohol sodium sulfovinate and essence after stirring 20min, mixing speed is adjusted
To 1500r/min, stirring 15min then prepares the toothpaste of the present embodiment.
Embodiment 6
The toothpaste of the present embodiment, its formula is made up of following each component：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
The present embodiment toothpaste is to be prepared by the following method：
Step 1
By sea salt, bladder-wrack extract, Crithmum maritimum extract, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate
It is dissolved in deionized water, aqueous phase is made in stirring and dissolving；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, and laruyl alcohol sodium sulfovinate, spirulina extract and essence are added after stirring 20min,
Mixing speed is adjusted to 1500r/min, stirring 15min and then prepares the toothpaste of the present embodiment.
Embodiment 7
The toothpaste of the present embodiment, its formula is made up of following each component：
The present embodiment toothpaste is to be prepared by the following method：
Step 1
Saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate are dissolved in deionized water, water is made in stirring and dissolving
Phase；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add prepared by step 1
Powder, mixing speed is 2000r/min, adds laruyl alcohol sodium sulfovinate and essence after stirring 20min, mixing speed is adjusted
To 1500r/min, stirring 15min then prepares the toothpaste of the present embodiment.
The clinical comparison of embodiment 8 is tested
The present embodiment have selected 70 patients for all suffering from oral peculiar smell, tooth mildew and tooth stain, by 70 patients with
Machine is divided into 7 groups of every group of 10 bit test persons.
The present embodiment is divided into 7 experimental groups, respectively using 1 group of the experiment of the toothpaste of embodiment 1, uses the toothpaste of embodiment 2
2 groups of experiment, 3 groups of the experiment using the toothpaste of embodiment 3,4 groups of the experiment using the toothpaste of embodiment 4, use the toothpaste of embodiment 5
Test 5 groups, 6 groups of the experiment using the toothpaste of embodiment 6 and using the toothpaste of embodiment 77 groups of experiment.
Toothpaste application method：Daily in the morning, afternoon and evening it is each 3 times using experiment toothpaste, each toothpaste dosage for head toothbrushes 2/3 length
Degree.
After 2 week, statistical results are as shown in table 1.
Each test group clinical effectiveness statistics of table 1
Table 1 is annotated：
It is invalid：Refer to patient after using experiment toothpaste, the symptom of its oral peculiar smell, tooth mildew and tooth stain changes without any
It is kind.
Effectively：Refer to patient after using experiment toothpaste, the symptom of its oral peculiar smell, tooth mildew and tooth stain, which has, necessarily to be changed
It is kind.
Recovery from illness：Refer to patient after using experiment toothpaste, the symptom of its oral peculiar smell, tooth mildew and tooth stain is wholly absent.
Effective percentage refers to：Efficiently individual quantity accounts for the ratio of this group of total number of persons in 10 experimenters of the group.
Cure rate refers to：Number of being fully recovered in 10 experimenters of the group accounts for the ratio of this group of total number of persons.
From the results shown in Table 1, oral care group containing marine element of the toothpaste of embodiment 7 not containing the present invention
Compound, only other components, therefore to oral problems such as halitosis, tooth stains without any effect；The toothpaste of embodiment 1 only contains xanthan
Glue, carrageenan and sea salt, therefore only have certain help to cleaning oral cavity；The toothpaste of embodiment 2,3,4,5 and 6 contains this
The oral care composition containing marine element of invention, it is clinically really to oral problems such as halitosis, tooth mildew and tooth stains
There is significant curative effect, and when algae extract is only any one in spirulina extract, bladder-wrack extract and Crithmum maritimum extract
When planting composition, its curative effect is not so good as the good effects of any two kinds mixing, and when spirulina extract, bladder-wrack extract and sea
When three kinds of algae extracts of anise extract are all present, its curative effect to Oral symptoms is best.
The announcement and teaching of book according to the above description, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula is changed and changed.Therefore, the invention is not limited in embodiment disclosed and described above, to the present invention's
Some modifications and changes should also be as falling into the scope of the claims of the present invention.Although in addition, being used in this specification
Some specific terms, but these terms are merely for convenience of description, do not constitute any limitation to the present invention.
Claims (10)
1. a kind of oral care composition containing marine element, it is characterised in that the oral care composition is by following parts by weight
Several each component compositions：
0.01~2 part of algae extract；
0.1~2 part of lotion thickener；
0.1~5 part of sea salt；
Above-mentioned algae extract is any one or two kinds in spirulina extract, bladder-wrack extract or Crithmum maritimum extract
Or the mixing of two or more arbitrary proportions；
Above-mentioned lotion thickener is carrageenan and xanthans according to 0.1:1~1:1 weight than mixing.
2. the oral care composition containing marine element according to claim 1, it is characterised in that the oral care composition
It is made up of each component of following parts by weight：
0.1~1 part of algae extract；
0.5~1.5 part of lotion thickener；
0.3~3 part of sea salt.
3. the oral care composition according to claim 1 or claim 2 containing marine element, it is characterised in that the spirulina is extracted
Thing is spirulina extract of the content of mineral substances more than 15%, and the bladder-wrack extract is protein content more than 70%
Bladder-wrack extract.
4. the oral care composition according to claim 1 or claim 2 containing marine element, it is characterised in that the algae extract
It is spirulina extract, bladder-wrack extract and Crithmum maritimum extract according to 0.05~1:0.5~1:1 weight than mixing.
5. the oral care composition according to claim 1 or claim 2 containing marine element, it is characterised in that the lotion thickener
It is carrageenan and xanthans according to 0.5:1~1:1 weight than mixing.
6. application of oral care composition of any one containing marine element in toothpaste is prepared described in claim 1-5.
7. apply according to claim 6, it is characterised in that the oral care composition containing marine element is in toothpaste
Addition be toothpaste gross weight 0.5%~3%.
8. apply according to claim 7, it is characterised in that the oral care composition containing marine element is in toothpaste
Addition be toothpaste gross weight 2%~3%.
9. a kind of toothpaste containing oral care composition described in claim 2, it is characterised in that the formulation of tooth-paste is by following each
Component composition：
Above-mentioned percentage is the percentage that each component accounts for toothpaste gross weight.
10. the preparation method of toothpaste described in a kind of claim 9, it is characterised in that the preparation method comprises the following steps：
Step 1
Sea salt, Crithmum maritimum extract, bladder-wrack extract, saccharin sodium, sodium benzoate, sodium phytate and crystalline sodium pyrophosphate are dissolved in
In deionized water, aqueous phase is made in stirring and dissolving；
Carrageenan, xanthans and silica are stirred and prepare powder；
Step 2
Added in the aqueous phase prepared to step 1 after glycerine, PEG-400, sorbierite stirring 10min, add powder prepared by step 1
Material, mixing speed is 2000r/min, and laruyl alcohol sodium sulfovinate, spirulina extract and essence are added after stirring 20min, will
Mixing speed adjusts to 1500r/min, stirring 15min and then prepares required toothpaste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710123859.5A CN107007538B (en) | 2017-03-03 | 2017-03-03 | Oral care composition containing marine elements, application of oral care composition and toothpaste containing marine elements |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710123859.5A CN107007538B (en) | 2017-03-03 | 2017-03-03 | Oral care composition containing marine elements, application of oral care composition and toothpaste containing marine elements |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107007538A true CN107007538A (en) | 2017-08-04 |
| CN107007538B CN107007538B (en) | 2020-06-09 |
Family
ID=59439652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710123859.5A Active CN107007538B (en) | 2017-03-03 | 2017-03-03 | Oral care composition containing marine elements, application of oral care composition and toothpaste containing marine elements |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107007538B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025563A (en) * | 2018-08-01 | 2019-07-19 | 北京柯瑞生物科技有限公司 | A kind of spirulina health-care shield gum toothpaste |
| CN115025022A (en) * | 2022-07-13 | 2022-09-09 | 博雅(广州)生物科技研究院有限公司 | Efficient antibacterial toothpaste and preparation method thereof |
| CN115297825A (en) * | 2020-03-17 | 2022-11-04 | 联合利华知识产权控股有限公司 | Composition comprising a metal oxide and a metal oxide |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097977A (en) * | 1993-07-27 | 1995-02-01 | 青岛德普日用化学工业有限公司 | The toothpaste that contains marine biological preparation |
| CN102525841A (en) * | 2011-12-16 | 2012-07-04 | 青岛海芬海洋生物科技有限公司 | Marine organism bacterium-removal oral care liquid |
| US20130287708A1 (en) * | 2010-12-09 | 2013-10-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Natural formulations |
| CN106309191A (en) * | 2015-06-30 | 2017-01-11 | 广德国际资讯有限公司 | Composite whitening toothpaste |
-
2017
- 2017-03-03 CN CN201710123859.5A patent/CN107007538B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097977A (en) * | 1993-07-27 | 1995-02-01 | 青岛德普日用化学工业有限公司 | The toothpaste that contains marine biological preparation |
| US20130287708A1 (en) * | 2010-12-09 | 2013-10-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Natural formulations |
| CN102525841A (en) * | 2011-12-16 | 2012-07-04 | 青岛海芬海洋生物科技有限公司 | Marine organism bacterium-removal oral care liquid |
| CN106309191A (en) * | 2015-06-30 | 2017-01-11 | 广德国际资讯有限公司 | Composite whitening toothpaste |
Non-Patent Citations (3)
| Title |
|---|
| [日]鸿巢章二等: "《水产利用化学》", 30 November 1994, 中国农业出版社 * |
| 作者未知: "这个在俄罗斯畅销到每秒卖一只的牙膏，连陈柏霖都在用", 《百度百家号（HTTPS://BAIJIAHAO.BAIDU.COM/S?ID=1555648985781578&WFR=SPIDER&FOR=PC）》 * |
| 袁昌齐等编: "《世界植物药》", 31 January 2013, 东南大学出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025563A (en) * | 2018-08-01 | 2019-07-19 | 北京柯瑞生物科技有限公司 | A kind of spirulina health-care shield gum toothpaste |
| CN115297825A (en) * | 2020-03-17 | 2022-11-04 | 联合利华知识产权控股有限公司 | Composition comprising a metal oxide and a metal oxide |
| CN115025022A (en) * | 2022-07-13 | 2022-09-09 | 博雅(广州)生物科技研究院有限公司 | Efficient antibacterial toothpaste and preparation method thereof |
| CN115025022B (en) * | 2022-07-13 | 2023-09-05 | 湖南互美电子商务有限公司 | Antibacterial toothpaste and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107007538B (en) | 2020-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005504109A5 (en) | ||
| CN103354741B (en) | Oral care composition | |
| CN106691883A (en) | Toothpaste and preparation method thereof | |
| CN108685833A (en) | Containing propolis, Radix Notoginseng, moutan bark, the coptis, Radix Glycyrrhizae toothpaste and preparation method thereof | |
| US10702465B2 (en) | Oral care formulation and method for the removal of tartar and plaque from teeth | |
| CN107485575A (en) | A kind of toothpaste of oral cavity helicobacter pylori resistant and anti-caries stomach strengthening function and preparation method thereof | |
| CN1294895C (en) | Natural and whitening tooth powder and production thereof | |
| CN107007538A (en) | A kind of oral care composition and application containing marine element, and the toothpaste containing marine element | |
| CN101365778A (en) | Clleasing composition | |
| CN102579286A (en) | Traditional Chinese medicine and Western medicine combined strong-efficacy desensitization toothpaste | |
| RU2457829C2 (en) | Mineral and vitamin complex for strengthening tooth enamel, composition for oral cavity hygiene and toothpaste | |
| EP1379223A1 (en) | Dental formulation | |
| JP2009184936A (en) | Composition for gum | |
| CN107028791A (en) | A kind of oral care composition and application containing sodium bicarbonate, and the toothpaste containing sodium bicarbonate | |
| CN104983744A (en) | Oral care composition containing periplaneta americana, oral care products and preparation methods of oral care composition and oral care products | |
| CN1713883A (en) | Oral compositions which mask the salty taste of sodium bicarbonate | |
| CN107411995A (en) | A kind of oral-cavity article containing sodium azulenesulfonate and preparation method thereof | |
| WO2020095099A1 (en) | Cosmetic oral care product | |
| CN108125815A (en) | A kind of toothpaste of oral cavity helicobacter pylori resistant and anti-caries stomach strengthening function and preparation method thereof | |
| CN105213216B (en) | A kind of natural disaccharide antibacterial shield tooth gargle and preparation method thereof | |
| CN108743442A (en) | Sodium azulenesulfonate, Cetylpyridinium Chloride and zinc ion compound formula mouth wash and preparation method | |
| CN104414898A (en) | Enteromorpha prolifera toothpaste | |
| CN102499902B (en) | Oral cavity care composition | |
| CN1038935A (en) | Jiekouye gargle | |
| KR20170090717A (en) | Mouthwash |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210508 Address after: 510555 room 922, No.2, Tengfei 1st Street, Zhongxin Guangzhou Knowledge City, Huangpu District, Guangzhou City, Guangdong Province (office only) Patentee after: Guangzhou Shuke Industrial Co.,Ltd. Address before: Room 704, 705, West, No. 64, 66, Jianzhong Road, Tianhe District, Guangzhou City, Guangdong Province Patentee before: GUANGZHOU WEIMEIZI INDUSTRIAL Co.,Ltd. |
|
| TR01 | Transfer of patent right |