CN106925597A - A kind of handling process of antibiotic bacterium dregs - Google Patents
A kind of handling process of antibiotic bacterium dregs Download PDFInfo
- Publication number
- CN106925597A CN106925597A CN201511024862.9A CN201511024862A CN106925597A CN 106925597 A CN106925597 A CN 106925597A CN 201511024862 A CN201511024862 A CN 201511024862A CN 106925597 A CN106925597 A CN 106925597A
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- China
- Prior art keywords
- antibiotic bacterium
- bacterium dregs
- handling process
- antibiotic
- degraded
- Prior art date
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- Granted
Links
- 241000894006 Bacteria Species 0.000 title claims abstract description 155
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 147
- 238000000034 method Methods 0.000 title claims abstract description 113
- 239000007787 solid Substances 0.000 claims abstract description 19
- 239000000463 material Substances 0.000 claims abstract description 14
- 239000000126 substance Substances 0.000 claims abstract description 12
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 7
- 238000006731 degradation reaction Methods 0.000 claims description 36
- 230000015556 catabolic process Effects 0.000 claims description 27
- 238000005422 blasting Methods 0.000 claims description 12
- 230000018044 dehydration Effects 0.000 claims description 12
- 238000006297 dehydration reaction Methods 0.000 claims description 12
- 239000012071 phase Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 10
- 229920006395 saturated elastomer Polymers 0.000 claims description 10
- 239000002893 slag Substances 0.000 claims description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 235000011114 ammonium hydroxide Nutrition 0.000 claims description 7
- 238000000926 separation method Methods 0.000 claims description 7
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- 239000007791 liquid phase Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000013019 agitation Methods 0.000 claims description 5
- 239000004098 Tetracycline Substances 0.000 claims description 3
- 150000001413 amino acids Chemical class 0.000 claims description 3
- 229910021529 ammonia Inorganic materials 0.000 claims description 3
- 235000019364 tetracycline Nutrition 0.000 claims description 3
- 150000003522 tetracyclines Chemical class 0.000 claims description 3
- 239000004475 Arginine Substances 0.000 claims description 2
- 239000004472 Lysine Substances 0.000 claims description 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 229940088710 antibiotic agent Drugs 0.000 claims description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
- 239000000920 calcium hydroxide Substances 0.000 claims description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims description 2
- 239000000292 calcium oxide Substances 0.000 claims description 2
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims description 2
- OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical class CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 claims description 2
- 239000003120 macrolide antibiotic agent Substances 0.000 claims description 2
- 229940041033 macrolides Drugs 0.000 claims description 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 2
- 229940040944 tetracyclines Drugs 0.000 claims description 2
- 150000003952 β-lactams Chemical class 0.000 claims description 2
- 125000003277 amino group Chemical group 0.000 claims 1
- 229930182478 glucoside Natural products 0.000 claims 1
- 150000008131 glucosides Chemical class 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 238000012545 processing Methods 0.000 abstract description 8
- 230000000717 retained effect Effects 0.000 abstract description 5
- 235000015097 nutrients Nutrition 0.000 abstract description 4
- 230000009965 odorless effect Effects 0.000 abstract description 2
- 239000010815 organic waste Substances 0.000 abstract description 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 49
- 229930182555 Penicillin Natural products 0.000 description 45
- 229940049954 penicillin Drugs 0.000 description 45
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 25
- 235000019750 Crude protein Nutrition 0.000 description 25
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 23
- 239000007789 gas Substances 0.000 description 21
- 238000009835 boiling Methods 0.000 description 13
- 230000000052 comparative effect Effects 0.000 description 11
- 229960003276 erythromycin Drugs 0.000 description 11
- 238000005516 engineering process Methods 0.000 description 8
- 239000000203 mixture Substances 0.000 description 6
- 244000005700 microbiome Species 0.000 description 5
- 239000007790 solid phase Substances 0.000 description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- 239000003513 alkali Substances 0.000 description 4
- 239000002585 base Substances 0.000 description 4
- 230000033228 biological regulation Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 230000000593 degrading effect Effects 0.000 description 3
- 239000000446 fuel Substances 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 239000002910 solid waste Substances 0.000 description 3
- 241000194108 Bacillus licheniformis Species 0.000 description 2
- 244000063299 Bacillus subtilis Species 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- 229920002101 Chitin Polymers 0.000 description 2
- 244000046052 Phaseolus vulgaris Species 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- 241000223259 Trichoderma Species 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 238000003763 carbonization Methods 0.000 description 2
- -1 cellulose Chemical class 0.000 description 2
- 235000019784 crude fat Nutrition 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 235000019371 penicillin G benzathine Nutrition 0.000 description 2
- 229940056360 penicillin g Drugs 0.000 description 2
- 230000000505 pernicious effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 229930182566 Gentamicin Natural products 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229940126575 aminoglycoside Drugs 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000006477 desulfuration reaction Methods 0.000 description 1
- 230000023556 desulfurization Effects 0.000 description 1
- 238000006471 dimerization reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 239000002737 fuel gas Substances 0.000 description 1
- 229960002518 gentamicin Drugs 0.000 description 1
- 239000002920 hazardous waste Substances 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000003864 humus Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000001819 mass spectrum Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- JKQOBWVOAYFWKG-UHFFFAOYSA-N molybdenum trioxide Chemical compound O=[Mo](=O)=O JKQOBWVOAYFWKG-UHFFFAOYSA-N 0.000 description 1
- 239000003345 natural gas Substances 0.000 description 1
- 239000003895 organic fertilizer Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000005373 pervaporation Methods 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000012805 post-processing Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000010563 solid-state fermentation Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
- B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
- B09B3/00—Destroying solid waste or transforming solid waste into something useful or harmless
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
- B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
- B09B3/00—Destroying solid waste or transforming solid waste into something useful or harmless
- B09B3/40—Destroying solid waste or transforming solid waste into something useful or harmless involving thermal treatment, e.g. evaporation
- B09B3/45—Steam treatment, e.g. supercritical water gasification or oxidation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
- B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
- B09B5/00—Operations not covered by a single other subclass or by a single other group in this subclass
Landscapes
- Engineering & Computer Science (AREA)
- Environmental & Geological Engineering (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Processing Of Solid Wastes (AREA)
Abstract
The present invention relates to the process field of organic waste, a kind of handling process of antibiotic bacterium dregs is disclosed, wherein, the handling process includes：In the presence of alkaline matter, and in confined conditions, at 40-260 DEG C, pending antibiotic bacterium dregs are degraded, catabolite is then carried out into the gentle phase material stream of isolated solid formation mass flow, and gaseous substance stream is post-processed.By above-mentioned technical proposal, Organic nutrient therein can be effectively retained while the residual antibiotic in effectively degraded antibiotic bacterium dregs, for the innoxious use of bacteria residue provides good precondition.Furthermore, technique of the invention can be prevented effectively from the problem that bacteria residue discharges bad smell in processing procedure and after treatment, and the bacteria residue odorless after treatment is environment-friendly.
Description
Technical field
The present invention relates to a kind of handling process of organic waste, in particular it relates to a kind of antibiotic bacterium dregs
Handling process.
Background technology
Antibiotic bacterium dregs are the solid waste of generation during Production by Microorganism Fermentation antibiotic.China
It is the first big country of antibiotics production, it is current country's antibiotic that the green of antibiotic bacterium dregs is degraded and utilized
A major challenge that manufacturing enterprise faces.
Antibiotic bacterium dregs are main by being blended in microbial cells tissue, culture medium, the production technology of residual
Solids phase residue in culture medium, such as filter aid are constituted.The composition of the antibiotic bacterium dregs includes：Source
Protein, fat in microorganism and culture medium, carbohydrate, chitin, vitamin, mineral matter
And the antibiotic of residual etc..Wherein, the moisture of antibiotic bacterium dregs ordinarily be about 70-95 weight %.
The ratio of crude protein is in 30-50 weight % or so in solid waste butt, carbohydrate such as cellulose,
The other compositions such as chitin, mineral matter account for the 40-70 weight % of solid waste butt, antibiotic
Residual concentration is general between 0.05-6 weight ‰.
At present, antibiotic bacterium dregs are according to hazardous waste disposal.Prior art provides the various ways for utilizing
Footpath：As CN104263451A provides a kind of bacteria residue green polymerization fuel and preparation method thereof, the method is proposed
Antibiotic bacterium dregs and coal slime and dimerization fuel are prepared as fuel and the scheme burned.
And for example CN104086244A provides the side that a kind of antibiotic bacterium dregs biofermentation converts humus
Method, the method carries out solid state fermentation using complex microorganism to material, wherein, the material includes antibiosis
Plain bacteria residue and stalk；The complex microorganism includes Trichoderma, bacillus subtilis and bacillus licheniformis,
And the Trichoderma, the weight ratio between bacillus subtilis and bacillus licheniformis are
(3-5):(2-4):(2-4).The method is used by solid fermentation by using bacteria residue as organic fertilizer raw material.
And for example CN103923599A provides a kind of adhesive prepared based on antibiotic bacterium dregs and bean powder
And preparation method thereof, the raw material of the adhesive includes antibiotic bacterium dregs, bean powder and additive.The method
What is proposed is by the scheme of the materialized application of antibiotic bacterium dregs.
Although the existing treatment technology of antibiotic bacterium dregs include incineration technology, Fertilizer Transformed technology, landfill and
Energy technology etc..However, the treatment of antibiotic bacterium dregs still suffers from lot of challenges.Firstly, for bacterium
The antibiotic remained in slag, in addition to burning and carbonization is heat-treated, is difficult to effectively in prior art solutions
Degraded, can reenter environment, as the hotbed for cultivating drug-resistant microorganisms.Second, antibiotic bacterium dregs
Stacking and processing procedure can discharge bad smell, surrounding environment is polluted so that the mistake for the treatment of
Journey faces bigger technical difficulty.
The content of the invention
The purpose of the present invention is to overcome defect of the prior art and provide a kind for the treatment of of antibiotic bacterium dregs
Technique, the handling process can effectively reduce the residual concentration of various antibiotic so that at this programme
The bacteria residue of reason meets the requirement of innoxious use, and can effectively improve the protein content in bacteria residue.
It was found by the inventors of the present invention that using burning and carbonization heat-treating methods, although can remove anti-
Raw element residual, but, the Organic nutrient such as thick protein, amino acid and other organic substances can not
Retained.And handling process of the invention can effectively remove residual antibiotic, nutrients can be retained again
Matter, that is, eliminate residual antibiotic and remain nutriment again and remove peculiar smell, thus should with good
Use prospect.
To achieve these goals, the present invention provides a kind of handling process of antibiotic bacterium dregs, wherein, institute
Stating handling process includes：In the presence of alkaline matter, and in confined conditions, at 40-260 DEG C, will
Pending antibiotic bacterium dregs are degraded, and it is gentle that catabolite then is carried out into isolated solid formation mass flow
Phase material stream, and gaseous substance stream is post-processed.
By above-mentioned technical proposal, can be while the residual antibiotic in effectively degraded antibiotic bacterium dregs
Organic nutrient therein is effectively retained, for the innoxious use of bacteria residue provides good precondition.
Furthermore, technique of the invention can be prevented effectively from bacteria residue release difficult in processing procedure and after treatment
The problem of smelling, the bacteria residue odorless after treatment is environment-friendly.
Preferably, after the handling process also includes degraded, it is depressured by the way of steam blasting so that
Pressure differential before and after step-down is at least 0.1MPa, more preferably 0.4-1.2MPa.In the process,
The cell in bacteria residue can be made fully to crush, rupture, and make wherein each component, such as cellulose and nutrition
The abundant separate out of material, such as protein, so as to residual antibiotic is big in being further ensured that antibiotic bacterium dregs
Amplitude is degraded, and is effectively retained nutritional ingredient.
Other features and advantages of the present invention will be described in detail in subsequent specific embodiment part.
Brief description of the drawings
Accompanying drawing is, for providing a further understanding of the present invention, and to constitute the part of specification, with
Following specific embodiment is used to explain the present invention together, but is not construed as limiting the invention.
In accompanying drawing：
Fig. 1 is a kind of processing technological flow figure of the antibiotic bacterium dregs of specific embodiment of the invention.
Specific embodiment
Specific embodiment of the invention is described in detail below.It should be appreciated that this place is retouched
The specific embodiment stated is merely to illustrate and explain the present invention, and is not intended to limit the invention.
According to the present invention, the handling process of the antibiotic bacterium dregs includes：In the presence of alkaline matter,
And in confined conditions, at 40-260 DEG C, pending antibiotic bacterium dregs are degraded, then will degraded
Product carries out the gentle phase material stream of isolated solid formation mass flow, and gaseous substance stream is post-processed.
Under preferable case, degradation temperature is more than or equal to 110 DEG C to being less than 200 DEG C, more preferably
120-190℃。
Solid formation mass flow of the present invention refers to solid-liquid of the antibiotic bacterium dregs by generation after degradation treatment
Mixture；Described gas gas-phase objects mass flow refers to gas mixing of the antibiotic bacterium dregs by generation after degradation treatment
Thing.
Handling process of the invention using in the presence of a basic, and in confined conditions,
40-260 DEG C, pending antibiotic bacterium dregs are degraded, can effectively be reduced antibiotic concentration, improved
Solid phase protein content, removes bacteria residue peculiar smell, so as to reach thermokalite degraded, harmless treatment and effective profit
With triple purposes of material.
According to the present invention, as long as effective degraded of the time guarantee antibiotic of the degraded and organic nutrition
Effective preservation of material, under preferable case, the time of the degraded is 0.05-180 minutes, enters one
Under step preferable case, when antibiotic bacterium dregs are processed using hot acid method, degradation time can be shorten to
3-80 minutes.
According to the present invention, the pressure of the degraded of the airtight condition can be 3KPa-5MPa, preferably
0.2-1.3MPa。
According to one of the invention preferred embodiment, in order to improve degradation efficiency, it is ensured that antibiotic bacterium
The abundant degraded and the retention of nutriment of slag, the present invention in the presence of a basic, and in closed bar
Under part, at 110-260 DEG C, more preferably greater than or equal to 110 DEG C are extremely less than 200 DEG C, further preferably
Degraded 0.1-180 minutes for 120-190 DEG C and under 3KPa-5MPa, preferably 0.2-1.3MPa,
After preferably 3-80 minutes, i.e. after degrading under these conditions, catabolite is being carried out into separation
Before, it is depressured by the way of steam blasting so that the pressure differential before and after step-down is at least 0.1MPa, excellent
Elect 0.4-1.2MPa as.It is depressured by the way of steam blasting, moment is by the pressure state in closed environment
Normal pressure or low pressure are down to from high pressure, so that the cell in antibiotic bacterium dregs is fully crushed, ruptured；And make
The abundant separate out of wherein each component, such as cellulose and nutriment, such as protein, so that antibiotic
Antibiotic in bacteria residue is significantly degraded, and further realizes goal of the invention of the invention.
According to the present invention, in the presence of alkaline matter, and under degradation condition of the present invention, will treat
The treatment mode degraded of antibiotic bacterium dregs can be：Before degrading will pending antibiotic bacterium dregs
Contacted with alkaline matter (for example, mixed pending antibiotic bacterium dregs with alkaline matter before charging,
Or mix pending antibiotic bacterium dregs with alkaline matter in charging), or will in degradation process
Pending antibiotic bacterium dregs are contacted with alkaline matter, it is also possible to both before degrading by pending antibiotic
Bacteria residue is contacted with alkaline matter, and again by pending antibiotic bacterium dregs and alkaline matter in degradation process
Contact.Wherein, described contact is preferably mixing.
According to the present invention, in the presence of alkaline matter, pending antibiotic bacterium dregs are degraded,
Under identical degradation time, degradation temperature can be reduced, or under identical degradation temperature, drop can be shortened
The solution time, while do not interfere with again, or even degradation efficiency can be improved.The present invention is to the alkaline matter
Species and consumption are not particularly limited, and under preferable case, the consumption of alkaline matter causes pending antibiotic
The pH value of bacteria residue is 7.5-12.
Further preferably, the alkaline matter can also be able to be weak base for highly basic, or highly basic with
The combination of weak base, for example, the highly basic can be NaOH and/or potassium hydroxide；The weak base can be with
Selected from one or more in ammoniacal liquor, liquefied ammonia, calcium hydroxide and calcium oxide.Additionally, the basic species
Matter can also be the amino acid that alkalescence is presented, such as lysine and/or arginine.Generally, for the ease of behaviour
The consideration of work, alkaline matter is generally used in the form of its aqueous solution, the addition of the aqueous solution of alkaline matter
Concentration can be 0.001-1M.
According to the present invention, the method that catabolite is carried out the gentle phase material stream of isolated solid formation mass flow
Can be carried out using method well known in the art, for example, by decompression, cooling, such as in cyclone separator
In, by the discharge of gaseous matter stream, and isolated solid formation mass flow.Meanwhile, the gaseous substance that will be discharged
Stream carries out conventional gas post processing well known in the art, to remove pernicious gas therein.Such as using life
The desulfurization of thing method, chemiadsorption etc. are removing the pernicious gases such as ammonia therein, hydrogen sulfide；For another example can be with
Using using the tail gas absorption for having peculiar smell or harmful components in the porous medias such as water or activated carbon absorption tail gas
Equipment, it would however also be possible to employ for the burning facility of incineration tail gas combustible component, when combustible component contains in tail gas
The fuel gas such as biogas, natural gas can be mixed when measuring relatively low carries out mixed burning.
According to the present invention, the water content of the pending antibiotic bacterium dregs can be 20-99 weight %, be
Can more efficiently treatment bacteria residue, improve treatment effeciency, it is specific as shown in figure 1, place of the invention
Science and engineering skill also includes：Before pending antibiotic bacterium dregs are degraded, will at least part of pending antibiotic
Bacteria residue carries out separation of solid and liquid, obtains pending antibiotic bacterium after the dehydration that moisture is 45-90 weight %
Slag and liquid phase substance stream, and by pending antibiotic bacterium dregs after dehydration individually degraded or with do not take off
The pending antibiotic bacterium dregs of water are degraded together.According to a specific embodiment of the invention, it is
Guarantee is effectively contacted with alkaline matter, can by pending antibiotic bacterium dregs and alkaline matter after dehydration
Directly individually degraded after contact, or can also be by pending antibiotic bacterium dregs and selectivity after dehydration
Ground contacted with alkaline matter be not dehydrated pending antibiotic bacterium dregs together with optionally connect with alkaline matter
Touch and degraded together.Wherein, " what is optionally contacted with alkaline matter is not dehydrated pending antibiosis
Plain bacteria residue " and " optionally being contacted with alkaline matter together " refer to this without dewater treatment
Antibiotic bacterium dregs can first be contacted before degraded with enough alkaline matters, directly wait to locate with after dehydration afterwards
Managing antibiotic bacterium dregs to be degraded together, or be somebody's turn to do the antibiotic bacterium dregs without dewater treatment to degrade
Preceding elder generation contacts with the alkaline matter of part, mix with pending antibiotic bacterium dregs after dehydration afterwards and with part
Alkaline matter is contacted and degraded together, furthermore is somebody's turn to do the antibiotic bacterium dregs without dewater treatment and is treated after being dehydrated
Treatment antibiotic bacterium dregs be mixed contacted with alkaline matter and together with degraded.
Further preferably, the technique also includes being dehydrated the isolated liquid phase substance stream to moisture containing
It is 55-85 weight % to measure, and individually carries out degraded and is preferably returned to together with pending antibiotic bacterium dregs after dehydration
Degraded.On the one hand, the dry substance concentration of pending antibiotic bacterium dregs is improved, it is possible to increase equipment
Treatment effeciency, is conducive to further reducing the residual concentration of antibiotic, improves solid phase protein content, separately
On the one hand, the liquid phase substance stream after separation of solid and liquid is further dehydrated, is such as returned after evaporation, concentration, with
Pending antibiotic bacterium dregs are degraded together after dehydration, it is possible to reduce steam consumption, and can be further
The a small amount of bacteria residue contained in liquid phase substance stream is carried out into degradation treatment together, treatment effect is improve, and
Also it is improved in continuous feed convenience and controllability.
Wherein, the method for the separation of solid and liquid can be used and carried out well known to a person skilled in the art method,
It is for instance possible to use the method such as plate-frame filtering.
According to the present invention, in order to further improve degradation effect, the degraded of the pending antibiotic bacterium dregs
It is preferred that carrying out under agitation.
According to the present invention, the present invention is preferably in air-liquid two-phase or gas, liquid, solid phase three-phase thermal response mistake
Degraded in journey, wherein, there is provided the thermal source of temperature includes steam and/or other heat carriers, mode of heating
Can directly be contacted with material and it be conducted heat, or heat carrier is by between container wall for heat carrier
Connect and give material heating, or above two mode of heating is combined and carried out.In the preferred case, there is provided temperature
Thermal source be steam, the steam can be saturated vapor and/or superheated steam, it is preferable that airtight condition
Vapour pressure more than or equal to synthermal lower vapor saturated vapor pressure.
The handling process of antibiotic bacterium dregs of the present invention can be carried out in equipment known in the art,
For example, can be in batch (-type) boiling vessel, such as conventional vertical digester, it is also possible in continuous steamer, such as
Carried out in conventional transverse tube type continuous steamer or tower continuous steamer.
According to the present invention, the species of the pending antibiotic bacterium dregs is not particularly limited, and can be existing
Various antibiotic bacterium dregs in technology, for example, being fermented from the various bacteria residues that can produce following antibiotic
The bacteria residue of generation and the bacteria residue material comprising the antibiotic, specifically, the antibiotic bacterium dregs can be with
Selected from containing beta-lactam class (such as cynnematin, penicillin), Tetracyclines, (such as tetracycline, soil are mould
Element), it is macrolides (such as erythromycin) class, aminoglycoside (such as gentamicin, streptomysin), many
The bacteria residue of one or more antibiotic in peptides and lincomycin class etc..
In the present invention, institute's finger pressure is absolute pressure.
The preferred embodiment of the present invention described in detail above, but, the present invention is not limited to above-mentioned reality
The detail in mode is applied, in range of the technology design of the invention, can be to technical side of the invention
Case carries out various simple variants, and these simple variants belong to protection scope of the present invention.
It is further to note that each particular technique feature described in above-mentioned specific embodiment,
In the case of reconcilable, can be combined by any suitable means, in order to avoid unnecessary
Repeat, the present invention is no longer separately illustrated to various possible combinations.
Additionally, can also be combined between a variety of implementation methods of the invention, as long as its
Without prejudice to thought of the invention, it should equally be considered as content disclosed in this invention.
Below will the present invention will be described in detail by embodiment.
In following examples, the pending antibiotic bacterium dregs are the bacteria residue for producing benzyl penicillin and erythromycin；
Wherein, the moisture of penicillin mushroom dregs is 83.2 weight %.Butt weight with penicillin mushroom dregs is as base
Standard, crude protein content is 44.1 weight %, and fiber content is 2.1 weight %, and crude fat content is 5.3
Weight %, the residual concentration of benzyl penicillin is 1.94 weight ‰ (1940ppm).Wherein, erythromycin bacterium
The moisture of slag is 85.3 weight %.On the basis of the butt weight of erythromycin bacterium slag, crude protein content
It is 29.8 weight %, fiber content is 1.4 weight %, and crude fat content is 11.4 weight %, erythromycin
Residual concentration be 1.49 weight ‰ (1490ppm).
Penicillin/erythromycin is remained in terms of ppm in catabolite in following embodiments and comparative example, 1ppm
Equivalent to 0.0001 weight %.
In following examples, the antibiotic crude protein content is determined by the method for kjeldahl determination and obtained,
By high performance liquid chromatography tandem mass spectrum method, (liquid chromatogram is Agilent to the content of antibiotic in bacteria residue
7890B, is equipped with binary gradient pump, vacuum on-line degassing machine, automatic sampler；Mass spectrograph is Agilent
Company 6540Q-TOF；Instrument controlling, data acquisition software and DAS are public using Agilent
The MassHnuter systems of department) method measures.
Chromatographic condition：HSS-T3 chromatographic columns, 100x2.1mm id., 1.8 μm of particle diameter, column temperature：40℃.
Mobile phase：A phases are that, containing the aqueous formic acid of 1 mass ‰, B phases are acetonitrile；Flow velocity 0.4ml/min.Sample introduction
Volume is 3 μ l.
Mass Spectrometry Conditions：Electron spray positive ion source (ESI+), voltage 3500V dries 300 DEG C of temperature degree,
Taper hole voltage 65V, 350 DEG C of sheath temperature degree dries gas and sheath throughput respectively 8L/min and 11L/min,
Atomization gas pressure 35psi, full scan pattern (50-1000amu).
In example 1 below -11 and comparative example 1-3, the operating temperature of batch (-type) vertical digester
40-300 DEG C, operating pressure 3KPa-10MPa；In embodiment 12-17 and comparative example 4, continous way
40-210 DEG C of boiling vessel operating temperature, operating pressure 3KPa-1.9MPa.
In following examples, gas processing device be using using activated carbon porous media absorb tail gas in have
The tail gas absorption equipment of peculiar smell or harmful components.
Embodiment 1
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Penicillin mushroom dregs are mixed into the pH value of regulation to penicillin mushroom dregs with ammoniacal liquor for 8.0, and by the antibiosis
Plain bacteria residue is placed in batch (-type) vertical digester, is passed through saturated vapor so that full in batch (-type) boiling vessel
With vapour pressure be 0.2MPa, airtight condition, at 120 DEG C, under agitation degrade 15 minutes.Adopt
Batch (-type) boiling vessel is carried out into quick pressure releasing with steam blasting mode, and (pressure differential before and after pressure release is
0.1MPa), discharge gas by cyclone separator separate and send into carry out in gas processing device after locate
Reason, and solid phase catabolite is isolated, measure is obtained, and Penicillin Residues are 1.98ppm in catabolite,
Crude protein content is 46.3 weight %.
Embodiment 2
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, degradation temperature is 180 DEG C.
Use steam blasting mode by batch (-type) boiling vessel carry out quick pressure releasing (pressure differential before and after pressure release for
0.9MPa).Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein content is 53.3
Weight %.
Embodiment 3
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, degradation temperature is 160 DEG C.
Use steam blasting mode by batch (-type) boiling vessel carry out quick pressure releasing (pressure differential before and after pressure release for
0.51MPa).Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein content is
50.9 weight %.
Embodiment 4
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, degradation temperature is 230 DEG C.
Use steam blasting mode by batch (-type) boiling vessel carry out quick pressure releasing (pressure differential before and after pressure release for
2.8MPa).Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein content is 45.3
Weight %.
Embodiment 5
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, degradation temperature is 199 DEG C,
Saturated vapor pressure during degraded in boiling vessel is 1.52MPa, and the pressure differential before and after pressure release is 1.45MPa.
Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein content is 52.5 weight %.
Embodiment 6
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, degradation time is 80 minutes.
Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein content is 48.8 weight %.
Embodiment 7
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, degradation time is 45 minutes.
Measure is obtained, and Penicillin Residues are 0.04ppm in catabolite, and crude protein content is 47.3 weight %.
Embodiment 8
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, used after the completion of degradation reaction
The mode of slow step-down carries out pressure release to normal pressure (moment pressure difference is both less than 0.1MPa).Measure is obtained, drop
Penicillin Residues are 2.72ppm in solution product, and crude protein content is 45.1 weight %.
Embodiment 9
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, by antibiotic bacterium dregs and ammoniacal liquor
Mixing regulation to the pH value of antibiotic bacterium dregs is 7.5.Batch (-type) boiling vessel is entered using steam blasting mode
Row quick pressure releasing (pressure differential before and after pressure release is 0.1MPa).Measure is obtained, penicillin in catabolite
It is 4.58ppm to remain, and crude protein content is 45.9 weight %.
Embodiment 10
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 1 processes antibiotic bacterium dregs, unlike, handled antibiotic bacterium dregs
It is erythromycin bacterium slag.Measure is obtained, and erythromycin residual is 0.98ppm, crude protein content in catabolite
It is 32.8 weight %.
Embodiment 11
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 2 processes antibiotic bacterium dregs, unlike, handled antibiotic bacterium dregs
It is erythromycin bacterium slag.Measure is obtained, and erythromycin residual is in catabolite<0.01ppm, crude protein content
It is 41.3 weight %.
Embodiment 12
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Penicillin mushroom dregs are mixed into the pH value of regulation to penicillin mushroom dregs with ammoniacal liquor for 8.5, by penicillin bacterium
Slag is placed in continuous transverse tube boiling vessel, is passed through saturated vapor so that the saturated vapor in continuously stewing device
It is 0.2MPa to press, airtight condition, at 120 DEG C, under agitation degrade 15 minutes.Using steam
Batch (-type) boiling vessel is carried out quick pressure releasing (pressure differential before and after pressure release is 0.1MPa), row by blasting method
Go out gas and separated by cyclone separator and sent into and post-processed in gas processing device, and isolate
Solid phase catabolite, measure is obtained, and Penicillin Residues are 1.42ppm, crude protein content in catabolite
It is 47.6 weight %.
Embodiment 13
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 12 processes penicillin mushroom dregs, unlike, degradation time is 100 points
Clock.Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein content is 50.2 weights
Amount %.
Embodiment 14
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 12 processes penicillin mushroom dregs, unlike, adopted after the completion of degradation reaction
Pressure release to normal pressure is carried out with the mode of slow step-down (moment pressure difference is both less than 0.1MPa).Measure is obtained,
Penicillin Residues are 2.79ppm in catabolite, and crude protein content is 45.8 weight %.
Embodiment 15
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 12 processes penicillin mushroom dregs, unlike, mix with penicillin mushroom dregs
Alkali used is NaOH, and the consumption of alkali makes pH value be 8.5.Measure is obtained, mould in catabolite
Element is remained<0.01ppm, crude protein content is 48.2 weight %.
Embodiment 16
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
By moisture for penicillin mushroom dregs described in 83.2 weight % carry out separation of solid and liquid by plate-frame filtering,
Obtain the first solids mass flow and liquids mass flow that water content is 74.2 weight %.Will be described isolated
Solids mass flow send into continuously stewing device that (consumption of ammoniacal liquor causes antibiotic bacterium dregs together with ammoniacal liquor
PH value be maintained at 8.5), be passed through saturated vapor so that saturated vapor pressure in continuously stewing device dimension
Hold in 0.2MPa, in airtight condition, maintenance is dropped at 120 DEG C, under agitation in continuously stewing device
Solution 15 minutes.Aforesaid liquid material stream is evaporated, is concentrated, obtain moisture for 71 weight %
The second solids mass flow, and this is continuously returned through pervaporation, the second solids mass flow being concentrated to give
Degraded together with the first solids mass flow into continuously stewing device.After the completion of degraded, using steam
Batch (-type) boiling vessel is carried out quick pressure releasing to normal pressure by blasting method.Discharge gas passes through cyclone separator
Post-processed in separation feeding gas processing device, measure is obtained, and Penicillin Residues are in catabolite
2.19ppm, crude protein content is 46.7 weight %.
Embodiment 17
This example demonstrates that the handling process and its result of the antibiotic bacterium dregs that the present invention is provided.
Method according to embodiment 16 processes penicillin mushroom dregs, unlike, by penicillin mushroom dregs and hydrogen
Sodium oxide molybdena water mixing regulation to the pH value of penicillin mushroom dregs is 12.Using steam blasting mode by continous way
Boiling vessel carries out quick pressure releasing (pressure differential before and after pressure release is 0.1MPa).Measure is obtained, catabolite
Middle Penicillin Residues are<0.01ppm, crude protein content is 44.5 weight %.
Comparative example 1
This comparative example is used for the handling process and its result of the antibiotic bacterium dregs for illustrating prior art.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, it is added without alkali, degradation temperature
It is 300 DEG C, pressure release to normal pressure (moment pressure difference is carried out by the way of slow step-down after the completion of degradation reaction
Both less than 0.1MPa).Measure is obtained, and Penicillin Residues are in catabolite<0.01ppm, crude protein contains
It is 12.4 weight % to measure.
Comparative example 2
This comparative example is used for the handling process and its result of the antibiotic bacterium dregs for illustrating prior art.
Method according to embodiment 1 processes penicillin mushroom dregs, unlike, it is added without alkali, degradation temperature
It is 300 DEG C, degradation time is 120 minutes, is carried out by the way of slow step-down after the completion of degradation reaction
Pressure release is to normal pressure (moment pressure difference is both less than 0.1MPa).Measure is obtained, Penicillin Residues in catabolite
For<0.01ppm, crude protein content is 6.2 weight %.
Comparative example 3
This comparative example is used for the handling process and its result of the antibiotic bacterium dregs for illustrating prior art.
Method according to embodiment 1 processes erythromycin bacterium slag, unlike, degradation temperature is 300 DEG C,
Degradation time is 120 minutes, and pressure release to normal pressure is carried out by the way of slow step-down after the completion of degradation reaction
(moment pressure difference is both less than 0.1MPa).Measure is obtained, and erythromycin residual is in catabolite<0.01ppm,
Crude protein content is 12.6 weight %.
Comparative example 4
This comparative example is used for the handling process and its result of the antibiotic bacterium dregs for illustrating prior art.
Method according to embodiment 12 processes penicillin mushroom dregs, unlike, degradation temperature is 35 DEG C,
(moment pressure difference is both less than to normal pressure by the way of slow step-down to carry out pressure release after the completion of degradation reaction
0.1MPa).Measure is obtained, and Penicillin Residues are 1850ppm in catabolite, and crude protein content is 43.6
Weight %.
Claims (13)
1. a kind of handling process of antibiotic bacterium dregs, it is characterised in that the handling process includes：
In the presence of alkaline matter, and in confined conditions, at 40-260 DEG C, pending antibiotic bacterium dregs are entered
Row degraded, then carries out the gentle phase material stream of isolated solid formation mass flow by catabolite, and by gas phase
Material stream is post-processed.
2. the handling process of antibiotic bacterium dregs according to claim 1, wherein, the pressure of degraded
It is 3KPa-5MPa, preferably 0.2-1.3MPa, the time of degraded is 0.05-180 minutes, preferably
3-80 minutes.
3. the handling process of antibiotic bacterium dregs according to claim 2, wherein, degradation temperature is
More than or equal to 110 DEG C to less than 200 DEG C, more preferably 120-190 DEG C.
4. the handling process of antibiotic bacterium dregs according to claim 3, wherein, place's science and engineering
Skill also includes：
After degradation, before catabolite is separated, it is depressured by the way of steam blasting so that
Pressure differential before and after step-down is at least 0.1MPa, preferably 0.4-1.2MPa.
5. the handling process of the antibiotic bacterium dregs according to any one in claim 1-3, wherein,
In the presence of alkaline matter, and in confined conditions, at 40-260 DEG C, by pending antibiotic bacterium dregs
The method degraded includes：Before pending antibiotic bacterium dregs are degraded, by pending antibiosis
Plain bacteria residue is contacted and/or in degradation process with alkaline matter, by pending antibiotic bacterium dregs and alkaline matter
Contact.
6. the handling process of antibiotic bacterium dregs according to claim 5, wherein, alkaline matter
Consumption makes the pH value of pending antibiotic bacterium dregs be 7.5-12.
7. the handling process of antibiotic bacterium dregs according to claim 6, wherein, the basic species
Matter is selected from liquefied ammonia, ammoniacal liquor, NaOH, potassium hydroxide, calcium hydroxide, calcium oxide and basic amine group
One or more in acid, it is preferable that the basic amino acid is lysine and/or arginine.
8. the handling process of antibiotic bacterium dregs according to claim 5, wherein, place's science and engineering
Skill also includes：Before pending antibiotic bacterium dregs are degraded, will at least part of pending antibiotic
Bacteria residue carries out separation of solid and liquid, obtains pending antibiotic bacterium after the dehydration that moisture is 45-90 weight %
Slag and liquid phase substance stream, and pending antibiotic bacterium dregs after dehydration are contacted and dropped with alkaline matter
Solution, or pending antibiotic bacterium dregs after dehydration are treated with not being dehydrated of optionally being contacted with alkaline matter
Treatment antibiotic bacterium dregs optionally contact with alkaline matter together and together with degraded.
9. the handling process of antibiotic bacterium dregs according to claim 8, wherein, place's science and engineering
Skill also includes that it is 55-85 weight % that the isolated liquid phase substance stream is dehydrated to moisture, and
Return is degraded together with pending antibiotic bacterium dregs after dehydration.
10. the handling process of the antibiotic bacterium dregs according to any one in claim 1-4, wherein,
The degraded is carried out under agitation.
The handling process of 11. antibiotic bacterium dregs according to claim 1 or 3, wherein, there is provided drop
Solve temperature thermal source be saturated vapor and/or superheated steam, and cause airtight condition vapour pressure be more than or
Equal to the saturated vapor pressure of synthermal lower vapor.
Place's science and engineering of 12. antibiotic bacterium dregs according to any one in claim 1-4,8 and 9
Skill, wherein, the water content of the pending antibiotic bacterium dregs is 20-99 weight %.
Place's science and engineering of 13. antibiotic bacterium dregs according to any one in claim 1-4,8 and 9
Skill, wherein, antibiotic bacterium dregs are selected from and contain beta-lactam class, Tetracyclines, macrolides, amino
One or more bacteria residue in glucosides, polypeptide and lincomycin series antibiotics.
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| CN108164292A (en) * | 2017-12-25 | 2018-06-15 | 伊犁川宁生物技术有限公司 | A kind of method that organic fertilizer is prepared using antibiotic bacterium dregs |
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| CN114535269A (en) * | 2022-01-19 | 2022-05-27 | 武汉回盛生物科技股份有限公司 | Harmless treatment method for antibiotic bacterium residues and application thereof |
| CN115672951A (en) * | 2022-09-27 | 2023-02-03 | 中南大学 | Efficient harmless treatment method for antibiotic fungi residues |
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