CN106902255A - A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to understanding mechanism according to Chinese traditional treatment Sjogren syndrome type of deficiency of both QI and YIN and a kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN for providing, each component and its mass parts ratio of the medicine are as follows：30~180g of ginseng, 100~260g of the raw Radix Astragali, 100~160g of the root of straight ladybell, 60~150g of the tuber of dwarf lilyturf, 60~150g of Radix Angelicae Sinensis, 50~120g of Ligusticum wallichii, 100~260g of the root of herbaceous peony, 30~120g of Fructus Aurantii, 60~180g of the stem of noble dendrobium, 100~180g of Poria cocos, 80~180g of peach kernel；The medicine that the present invention is provided is a good Chinese prescription.

Description

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN The field of thing, the pill medicine for particularly being used for Sjogren syndrome type of deficiency of both QI and YIN patient and preparation method thereof.

Background technology

Motherland's medical science thinks：Sjogren syndrome is that a kind of infringement exocrine gland is especially slow based on salivary gland and lachrymal gland Property autoimmune disease.In recent years, this sick incidence of disease is in obvious ascendant trend, and this sick incidence of disease is 0.5% -5%, about 90% is female patient, most of middle age onset, is more common in 30-50 Sui women, significantly impacts the life matter of patient groups Amount.In addition to clinical dry, the xerophthalmia shape occurred except the function of having salivary gland and lachrymal gland is damaged, still involve other exocrine glands And its corresponding organ is involved and the impaired performance of multisystem occurs.

At present：The method that doctor trained in Western medicine there is no radical cure to this disease, especially for early primary Patients with Sjogren Syndrome, according to 2005《Rheumatism clinic diagnosis guide》The suggestion early stage of proposition is by application eyedrops, MC or corresponding non- Steroid medicine, make medication symptomatic treatment slowly, therapeutic effect is limited, therefore on the premise of doctor trained in Western medicine treats this disease without effective ways, Traditional Chinese medicine is given we have proposed new challenge in terms of conditions of patients is improved.

Sjogren syndrome is doctor trained in Western medicine name of disease, and this disease is recorded in TCM Document without corresponding name of disease, but with regard to its clinical manifestation The categories such as dry card, dry numbness, dry poison, consumptive disease can be belonged to.Be named as this disease " dry by contemporary tcm clinical practice expert LU Zhi-zheng professor Numbness ", the generation of this disease mainly damages qi-blood-body fluid and causes yin jin to be lost by dryness evil, deficiency of qi and blood, loses limbs tendon and vessel and supports, Yu Xue Bi hinders, and phlegm condenses poly-, and train of thought is obstructed, causes limbs pain, and very then skin is dull and heavy, organ injury.

The basic norm that existing most of doctors treat dry numbness is that the interpretation of the cause, onset and process of an illness follows deficiency of YIN-blood, body fluid depletion causing blood stasis, dry very detoxification, During treatment with nourshing Yin and drynsessmoistening prescription, it is clearing heat and detoxicating, promoting blood circulation and removing blood stasis based on.But during clinical diagnosis and treatment, it is confined to clinical observation more And experience introduction, very greatly, not very clearly, clinician is limited only to the state of an illness actual efficacy diagnosis and treatment standard randomness Each understanding, strongly limit the raising of dry numbness clinical efficacy, while also limit the system to disease understanding in itself and thinking One.

So, it is ability with regard to how to find a kind of Chinese medicine composition that can effectively treat Sjogren syndrome type of deficiency of both QI and YIN Field technique personnel problem urgently to be resolved.

The content of the invention

With continuing to develop for China's traditional Chinese medicine, on treatment Sjogren syndrome type of deficiency of both QI and YIN, people gradually anticipate The advantage of Chinese traditional treatment Sjogren syndrome type of deficiency of both QI and YIN, and good effect, instant effect, toxic and side effect are over the course for the treatment of known The advantage such as small, for the present situation of existing western medical treatment Sjogren syndrome type of deficiency of both QI and YIN, it is offer one that the purpose of the present invention is The pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN is planted, recovers strong early to solve Sjogren syndrome type of deficiency of both QI and YIN patient The problem of health.The medicine is, with common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively to treat State the card of Sjogren syndrome type of deficiency of both QI and YIN one.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats Sjogren syndrome Pill medicine of type of deficiency of both QI and YIN and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

30~180g of ginseng, 100~260g of the raw Radix Astragali, 100~160g of the root of straight ladybell, 60~150g of the tuber of dwarf lilyturf, 60~150g of Radix Angelicae Sinensis, Ligusticum wallichii 50~120g, 100~260g of the root of herbaceous peony, 30~120g of Fructus Aurantii, 60~180g of the stem of noble dendrobium, 100~180g of Poria cocos, 80~180g of peach kernel, Appropriate starch.

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN and preparation method thereof, it is characterised in that the medicine Each component and its mass parts of thing are than as follows：

38~150g of ginseng, 115~230g of the raw Radix Astragali, 115~140g of the root of straight ladybell, 68~130g of the tuber of dwarf lilyturf, 68~130g of Radix Angelicae Sinensis, Ligusticum wallichii 60~105g, 115~230g of the root of herbaceous peony, 38~105g of Fructus Aurantii, 68~150g of the stem of noble dendrobium, 115~160g of Poria cocos, 90~150g of peach kernel, Appropriate starch.

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN and preparation method thereof, it is characterised in that it is described " most Each component and its mass parts of the medicine of good scheme " are than as follows：

Ginseng 130g, raw Radix Astragali 200g, the root of straight ladybell 120g, tuber of dwarf lilyturf 115g, Radix Angelicae Sinensis 115g, Ligusticum wallichii 95g, root of herbaceous peony 200g, Fructus Aurantii 95g, Stem of noble dendrobium 130g, Poria cocos 140g, peach kernel 130g, appropriate starch.

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN and preparation method thereof, it is characterised in that the side Method comprises the following steps to be prepared from：

A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked into impurity, dust and drying, be ground into superfine end according to mass parts ratio and treat With；

B, the method that Chinese kmedicine bolus agent is prepared according to tradition, after ground superfine myrrh thing and starch are sieved, are put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.8mm~4.0mm）, and then dry, sealed packaging is Can.

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN and preparation method thereof, it is characterised in that the clothes It is with method：Three times a day to take, the morning, noon and afternoon service once the water pill medicine that will be prepared, and dosage 5.5g/time, meal After take.It is within 7 days a course for the treatment of, 2~3 courses for the treatment of of taking medicine, symptom gradually mitigates or fully recovers.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Ginseng, nature and flavor：Sweet slight bitter, temperature, with reinforcing vital energy, take off the effect of promoting the production of body fluid, calm the nerves admittedly, and for treating, internal lesion caused by overexertion is deficient, food Less, food, stool lingering diarrhea are told in burnout, gastric disorder causing nausea, empty cough and asthma promotees, spontaneous perspiration takes off cruelly, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, disappear Yearningly, woman uterine bleeding, children shy and not multiple, all qi-blood-body fluid deficiencies etc. empty long slowly；

The raw Radix Astragali, nature and flavor：Sweet, tepor, the effect of with invigorating qi for strengthening superficies, torr sore myogenic, sharp water, for treat deficient qi and blood, The diseases such as spontaneous perspiration, rush down prolapse of the anus for a long time, the prolapse of uterus, ephritis edema, albuminuria, diabetes, chronic ulcer；

The root of straight ladybell, nature and flavor：Sweet, slight bitter, cold nature, the effect of with replenishing the vital essence and removing heat, moistening lung for removing phlegm, reinforcing stomach reg fluid, for treating Yin chronic cough, consumptive disease are coughed few phlegm blood, cough caused by dryness phlegm, abnormal heat larynx numbness, injury thirst；

The tuber of dwarf lilyturf, nature and flavor：Sweet, slight bitter, it is slightly cold, the effect of with nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, for treating dryness of the lung dry cough, consumptive disease The diseases such as cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria；

Radix Angelicae Sinensis, nature and flavor：It is sweet, pungent, bitter, warm in nature, with enriching blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treating The all cards of the deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, Disorder lumps in the abdomen knot are poly-, uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness, intestines are dry and shit is difficult, red The disease such as weight, ulcer sores, injury from falling down after dysentery；

Ligusticum wallichii, nature and flavor：Pungent, temperature, the effect of with promote breath and open depression, wet method wind-dryness, promoting blood circulation and stopping pain, for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores, irregular menstruation, lump in the abdomen stomachache, chest side of body thorn Bitterly, the disease such as tumbling and swelling, arthralgia pain due to rheumatism；

The root of herbaceous peony, nature and flavor：Bitter, acid, it is slightly cold, blood-nourishing and battalion, relieving spasm to stop pain, the effect of hold back high and level tone liver, for treating irregular menstruation, passing through The diseases such as row stomachache, uterine bleeding, spontaneous perspiration, night sweat, side of body rib epigastric pain, four limbs contraction pain, headache, dizziness；

Fructus Aurantii, nature and flavor：Bitter, acid, cold nature, the effect of with qi-regulating chest wide, row stagnant disperse accumulations, for treating septum pectorale feeling of fullness, side of body rib The disease such as weight, prolapse of the anus, prolapse of uterus after distending pain, accumulation of food in the stomach and intes tine due to indigestion, abdominal fullness and distention, diarrhea；

The stem of noble dendrobium, nature and flavor：It is sweet, be slightly cold, the effect of waist strong with the beneficial stomach that promotes the production of body fluid, nourishing Yin and clearing heat, moistening lung kidney-nourishing, improving eyesight, for treating Consumption of body fluid caused by febrile disease, dry polydipsia, deficiency of stomach-Yin, stomachache retch, dryness of the lung dry cough, abnormal heat are not moved back, impairment of yin mesh is dark, waist and knee is weak；

Poria cocos, nature and flavor：It is sweet, light, flat, the effect of with sharp water medicine, diuretics with the action of eliminating dampness, for treat difficult urination, oedema turgor, Phlegm and retained fluid coughs inverse, vomiting, spleen eating less, diarrhea, palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea；

Peach kernel, nature and flavor：It is bitter sweet, flat, it is nontoxic, the effect of with the blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis Store the diseases such as blood, wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood.

Medicine of the present invention is the principle based on Chinese traditional treatment Sjogren syndrome type of deficiency of both QI and YIN, from according to Sjogren syndrome gas The pathomechanism of Yin bivacuity type and pharmacological action are thought：With regard to Sjogren syndrome type of deficiency of both QI and YIN, in medicine provided by the present invention Each raw material herbal medicine efficacy play altogether, have good therapeutic effect to above-mentioned disease.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned Sjogren syndrome type of deficiency of both QI and YIN, uses Medicine effect prepared by the formula is good, and instant effect is a Chinese prescription treated both principal and secondary aspect of disease, and is particularly suitable for Clinical practice.Below It is described in further detail with reference to specific embodiment of the invention：

Embodiment 1：

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Ginseng 130g, raw Radix Astragali 200g, the root of straight ladybell 120g, tuber of dwarf lilyturf 115g, Radix Angelicae Sinensis 115g, Ligusticum wallichii 95g, root of herbaceous peony 200g, Fructus Aurantii 95g, Stem of noble dendrobium 130g, Poria cocos 140g, peach kernel 130g, appropriate starch.

Embodiment 2：

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Ginseng 150g, raw Radix Astragali 230g, the root of straight ladybell 140g, tuber of dwarf lilyturf 130g, Radix Angelicae Sinensis 130g, Ligusticum wallichii 105g, root of herbaceous peony 230g, Fructus Aurantii 105g, stem of noble dendrobium 150g, Poria cocos 160g, peach kernel 150g, appropriate starch.

Embodiment 3：

A kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Ginseng 180g, raw Radix Astragali 260g, the root of straight ladybell 160g, tuber of dwarf lilyturf 150g, Radix Angelicae Sinensis 150g, Ligusticum wallichii 120g, root of herbaceous peony 260g, Fructus Aurantii 120g, stem of noble dendrobium 180g, Poria cocos 180g, peach kernel 180g, appropriate starch.

Model case

Through clinical conditions Sjogren syndrome type of deficiency of both QI and YIN patient totally 880, the age is 690 of more than 43 years old, only 190 is less than 43 years old.710, effective 100, invalid 70 fully recovered in 880 patients.Total effective rate is up to 92%.

Claims (3)

1. a kind of pill medicine for treating Sjogren syndrome type of deficiency of both QI and YIN, it is characterised in that each component of the medicine and Its mass parts is than as follows：

30~180g of ginseng, 100~260g of the raw Radix Astragali, 100~160g of the root of straight ladybell, 60~150g of the tuber of dwarf lilyturf, 60~150g of Radix Angelicae Sinensis, Ligusticum wallichii 50~120g, 100~260g of the root of herbaceous peony, 30~120g of Fructus Aurantii, 60~180g of the stem of noble dendrobium, 100~180g of Poria cocos, 80~180g of peach kernel, Appropriate starch.

2. it is according to claim 1 treatment Sjogren syndrome type of deficiency of both QI and YIN pill medicine, it is characterised in that the medicine Each component and its mass parts of thing are than as follows：

38~150g of ginseng, 115~230g of the raw Radix Astragali, 115~140g of the root of straight ladybell, 68~130g of the tuber of dwarf lilyturf, 68~130g of Radix Angelicae Sinensis, Ligusticum wallichii 60~105g, 115~230g of the root of herbaceous peony, 38~105g of Fructus Aurantii, 68~150g of the stem of noble dendrobium, 115~160g of Poria cocos, 90~150g of peach kernel, Appropriate starch.

3. according to claim 1 to 2 treatment Sjogren syndrome type of deficiency of both QI and YIN pill medicine, it is characterised in that institute Each component and its mass parts of medicine are stated than as follows：

Ginseng 130g, raw Radix Astragali 200g, the root of straight ladybell 120g, tuber of dwarf lilyturf 115g, Radix Angelicae Sinensis 115g, Ligusticum wallichii 95g, root of herbaceous peony 200g, Fructus Aurantii 95g, Stem of noble dendrobium 130g, Poria cocos 140g, peach kernel 130g, appropriate starch.