CN108704108A - A kind of medicine pill for treating gout - Google Patents

A kind of medicine pill for treating gout Download PDF

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Publication number
CN108704108A
CN108704108A CN201810937867.8A CN201810937867A CN108704108A CN 108704108 A CN108704108 A CN 108704108A CN 201810937867 A CN201810937867 A CN 201810937867A CN 108704108 A CN108704108 A CN 108704108A
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radix
medicine
heat
clearing
gout
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李珍斌
谢朝林
赵倩兰
黄得黎
石新明
严玲
邹靖
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Gongan County Hospital Of Traditional Chinese Hospital
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Gongan County Hospital Of Traditional Chinese Hospital
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
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    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents

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Abstract

The present invention relates to a kind of medicine pills, and in particular to a kind of medicine pill for treating gout.The medicine pill uses Cortex Phellodendri, rhizoma atractylodis, coix seed, radix cyathulae heat-clearing and damp-drying drug to remove the red and swollen heat pain of damp invasion of lower energizer, and medicine reaches sick institute, and four are harmonious the clean source of clear stream, and giving consideration to both the incidental and fundamental is altogether monarch drug in a prescription;Radix Salviae Miltiorrhizae, Radix Curcumae, corydalis tuber, radix paeoniae rubra, Caulis Spatholobi can be promoting blood circulation and removing blood stasis, relieve pain promoting the circulation of qi, monarch drug in a prescription heat-clearing can be assisted again, with monarch drug in a prescription function in clear the heat of coke be ministerial drug, umbellate pore furgus, rhizoma alismatis, Asiatic plantain, dandelion clearing heat and promoting diuresis, the lower coke water of profit is wet, it is adjutant that it is preferably promoting blood circulation and removing blood stasis, which to help ministerial drug, dried orange peel, lily are to make medicine, burnt moisture in clear and invigorating the spleen, and the work(of clearing damp is preferably reached with the cooperation of other Chinese medicines.The medicine pill utilizes the synthesis co-action for treating gout of various drugs, to human body Small side effects, without decoction, with therapy simplicity, cheap, significant in efficacy feature, with clearing heat and expelling damp, promoting blood circulation and stopping pain, treating both manifestation and root cause of disease work(, treatment gout effective percentage is up to 97% or more.

Description

A kind of medicine pill for treating gout
Technical field
The present invention relates to a kind of medicine pills, and in particular to a kind of medicine pill for treating gout.
Background technology
Gout is to cause uric acid crystal to be deposited on joint and periarticular group since purine metabolic disturbance, blood uric acid increase Knit caused characteristic arthritis.Clinically with hyperuricemia, characteristic acute arthritis recurrent exerbation, gout calculus shape As feature, severe patient can cause joint deformity and dysfunction, acute obstructive nephrosis or gouty nephropathy.Gout category traditional Chinese medicine " bi Zheng " scope, but to the cause of disease of gout, the interpretation of the cause, onset and process of an illness at present still without exact definition.Have from ancient times " goat from the beginning of for liver and spleen it is same With the passing of time disease must involve in kidney, cause gouty nephropathy " say.The disease of Chinese medicine gout, relationship is whether the ups and downs of liver and spleen kidney.
At present to the drug therapy of the disease acute stage, mainly use colchicin, non-steroid anti-inflammatory drug and steroids with It relieves pain to the ill, inhibit blood uric acid to generate or promote its excretion to control, such curative effect of medication is definite, but takes many patients for a long time It is not resistant to its side effect or use due to some patients itself are with hypertension, diabetes chronic diseases to some Western medicine It is avoided;The outer for the treatment of acute gout in the market is controlled drug mainly and is had dispel pain liniment, golden red alleviating pain and detumescence tincture, hippocampus of Moschus and relax Cream living and Liushen Pills externally applied drug can obviously improve patients acuity gout symptom, but long-term treatment can not be ensured;Arthroscope can To treat gonyargra arthritis, the intra-articular lesion of the comprehensive inspection and evaluation of knee joint and function, arthroscope is carried out when necessary Inspection and cleaning can avoid urarthritis from recurring to greatest extent;Operative treatment is spent greatly, for being not up to operation standard Gout can not improve.So need a kind of toxic side effect it is small, it is cheap, convenient for taking, the treating both manifestation and root cause of disease that therapeutic effect is excellent Treatment gout medicine pill.
Invention content
It is an object of the present invention in view of the above shortcomings of the prior art, one kind is provided and is formed by prepared from traditional Chinese medicines, for It is simultaneous to reach sample for the pathogenesis of gout, heat-clearing wind-dispelling, eliminating toxic dampness and heat, the acute and chronic good analgesic effect caused by gout Control the medicine pill of the treatment gout of purpose.
The present invention is to realize above-mentioned purpose by following technical solution:
A kind of medicine pill for treating gout, which is characterized in that it is made of the raw material of following weight parts(Unit:Part):
Cortex Phellodendri 5-15 rhizoma atractylodis 5-15 coix seeds 10-20
Radix cyathulae 10-20 Radix Salviae Miltiorrhizae 10-20 Radix Curcumaes 5-15
Corydalis tuber 10-20 radix paeoniae rubra 10-20 Caulis Spatholobis 10-20
Umbellate pore furgus 10-20 rhizoma alismatis 5-15 Asiatic plantains 10-20
Dandelion 20-30 dried orange peel 5-15 lilies 7-17.
Preferably, the medicine pill of above-mentioned treatment gout, it is made of the raw material of following weight parts:(Unit:Part)
Cortex Phellodendri 7-12 rhizoma atractylodis 7-12 coix seeds 12-17
Radix cyathulae 12-17 Radix Salviae Miltiorrhizae 12-17 Radix Curcumaes 7-12
Corydalis tuber 12-17 radix paeoniae rubra 12-17 Caulis Spatholobis 12-17
Umbellate pore furgus 12-17 rhizoma alismatis 7-12 Asiatic plantains 12-17
Dandelion 22-27 dried orange peel 7-12 lilies 9-15.
Preferably, the medicine pill of above-mentioned treatment gout, it is made of the raw material of following weight parts:(Unit:Part)
10 rhizoma atractylodis of Cortex Phellodendri, 10 coix seed 15
15 Radix Salviae Miltiorrhizae of radix cyathulae, 15 Radix Curcumae 10
15 radix paeoniae rubra of corydalis tuber, 15 Caulis Spatholobi 15
15 rhizoma alismatis of umbellate pore furgus, 10 Asiatic plantain 15
25 dried orange peel of dandelion, 10 lily 12.
In above-mentioned prescription, to remove the red and swollen heat pain of damp invasion of lower energizer, medicine reaches for Cortex Phellodendri, rhizoma atractylodis, coix seed, radix cyathulae heat-clearing and damp-drying drug Sick institute, four are harmonious the clean source of clear stream, and giving consideration to both the incidental and fundamental is altogether monarch drug in a prescription;Radix Salviae Miltiorrhizae, Radix Curcumae, corydalis tuber, radix paeoniae rubra, Caulis Spatholobi can promoting blood circulations The stasis of blood relieves pain promoting the circulation of qi, and can assist monarch drug in a prescription heat-clearing, and the heat with the clear middle coke of monarch drug in a prescription function is ministerial drug, umbellate pore furgus, rhizoma alismatis, Asiatic plantain, Pu Gong English clearing heat and promoting diuresis, the lower burnt water of profit is wet, and it is adjutant that assistant ministerial drug is preferably promoting blood circulation and removing blood stasis, and dried orange peel, lily are to make medicine, burnt moisture in clear and Invigorating the spleen preferably reaches the work(of clearing damp with the cooperation of other Chinese medicines.
In the material component of the present invention, the pharmacology and drug effect of each component raw material are:
Cortex Phellodendri:Nature and flavor:It is bitter;It is cold.Channel tropism:Kidney channel;Bladder;Large intestine channel.There is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment. 《Pearl sac》:" Cortex Phellodendri has been used six:It is fiery to rush down bladder dragon, one;Diuresis knot, two;Except lower coke is wet swollen, three;Dysentery foreknowledge Blood, four;Subumbilical pain, without;Kidney tonifying is insufficient, zhuanggu marrow, and six ".
Rhizoma atractylodis:Nature and flavor:Bitter, temperature, fragrance and dry, returns spleen, stomach, Liver Channel.It is drying damp and strengthening spleen;Wind-damp dispelling;Improving eyesight.Main wet tired spleen Stomach;Burnout;Born of the same parents' ruffian abdominal distension;Loss of appetite;Vomiting and having loose bowel;Phlegm and retained fluid;It is wet swollen;Exterior syndrome folder is wet;Head body weight pain;Bi Zheng warm nature; Podomere, which is ached, to be weighed;Impotence folds in a garment;Yctalopia.
Coix seed:Nature and flavor:It is sweet it is light be slightly cold, solely enter Yangming Channel clearing damp heat and sharp joint;Returns spleen, stomach, lung channel.According to《Herbal guiding principle Mesh》Recording coix seed energy, " invigorating spleen and reinforcing stomach, tonifying lung heat-clearing, removes wind prevailing over dampness.It cooks a meal food, controls cold air.Decoct drink, diuresis heat gonorrhea ".《Medicine Property assign》Cloud:" Job's tears manage tinea pedis and curing rheumatism ".
Radix cyathulae:It is bitter, sweet, sour, flat, return liver and kidney channel;The root of bidentate achyranthes is walked and can be mended, and property is apt to downlink, therefore enters liver kidney.It is logical by the stasis of blood Through, filling liver kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia is ensuringd proper downward flow of the blood, is guided drugs to illness station.《A supplement to augmented materia medica》:All medicine downlinks can be drawn.《Book on Chinese herbal medicine Through dredging》:Main cold-dampness Impotence numbness, spasm of limbs, the goinyalgia person of being unable to flex and stretch the extremities, liver and spleen kidney deficiency, then the heresy visitor of cold-dampness form numbness, and disease four Limb contraction, goinyalgia are unable to flex and stretch the extremities.The root of bidentate achyranthes can make that Cortex Phellodendri, rhizoma atractylodis specially enter lower burnt and clearing damp is hot.
Radix Salviae Miltiorrhizae:Bitter is cold in nature, the thoughts of returning home, pericardium, Liver Channel;With promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, cool blood to disappear carbuncle, relieving restlessness tranquilizing the mind Effect;《Japan hanako materia medica》:" blood-nourishing sedate leads to reason joint, controls cold and hot labor, the tired pain of joint, four limbs are unsuccessful, and apocenosis is unsuccessful ".
Radix Curcumae:Acrid flavour, hardship, it is cold in nature;There is promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, cholagogic to move back for Return liver, courage, the heart channel of Hang-Shaoyin Yellow effect;《Essentials of Materia Medica》:" promoting the circulation of qi, Xie Yu let out blood, broken stasis of blood.Cool heart heat, solves liver depression, controls married woman's passages through which vital energy circulates and drives in the wrong direction ".
Corydalis tuber:Warm-natured, acrid flavour, hardship, the thoughts of returning home, liver, the spleen channel have effects that promoting blood circulation, promoting the circulation of qi, analgesic.《Compendium of Materia Medica》: " corydalis tuber, the stagnation of the circulation of vital energy in energy promoting circulation of blood, therefore all pains above and below all over the body are specially controlled, it is simply fantastic among.Lid corydalis tuber promoting blood circulationization gas, the One product medicine ".
Radix paeoniae rubra:Bitter is slightly cold, return liver warp, can clearing heat and cooling blood, removing blood stasis and analgesics;《Sheng Nong's herbal classic》:" main perverse trend abdominal pain, is removed Blood-arthralgia breaks hard product, fever and chills hernia lump in the abdomen, analgesic, diuresis ".
Caulis Spatholobi:Nature and flavor:Bitter, sweet, warm.Channel tropism:Return liver and kidney channel.Major function:It enriches blood, invigorates blood circulation, dredging collateral.For menstruation It is uncomfortable, blood deficiency chlorosis, paralysis and numbness, arthralgia pain due to rheumatism.
Umbellate pore furgus:Nature and flavor:Sweet and neutral, it is nontoxic.Return kidney, bladder warp.Clearing damp and promoting diuresis.Control difficult urination, oedema, diarrhea, stranguria with turbid discharge, Under band.
Rhizoma alismatis:Nature and flavor:It is sweet, light, flat;Return kidney, bladder warp, be clearing damp and promoting diuresis key medicine,《Haigoushen》:" main kidney deficiency essence goes out certainly, Five leaching are controlled, sharp bladder heat declares water flowing ".《Herbal outline》:" dehumidifying is treating stranguria, quenches the thirst, harnesses the river swollen, stopping leak dysentery helps it with umbellate pore furgus ".
Asiatic plantain:Nature and flavor:It is sweet, it trembles with fear, returns hand sun, Yangming Channel.Li Shui, heat-clearing, improving eyesight, eliminating the phlegm are used for urinary obstruction, leaching It is turbid, under band, hematuria, jaundice, edema, hot dysentery diarrhea, nosebleed epistaxis, red eye, swell pain, laryngalgia, cough, skin ulcer.
Dandelion:Nature and flavor:It is bitter, sweet, it trembles with fear.Channel tropism Return liver, stomach.Major function is clearing heat and detoxicating, dispersing swelling and dissipating binds, and diuresis is logical Leaching.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
Dried orange peel:Nature and flavor:Temperature, acrid flavour, hardship;Returns spleen, lung channel;With eliminating dampness and eliminating phlegm, the effect of regulating qi-flowing for strengthening spleen;《Legendary god of farming's book on Chinese herbal medicine Through》:" the main heat of lump in the abdomen in the heart, inverse gas, sharp trough, long term usage deodorizing, lower gas ".
Lily:Nature and flavor:It is sweet in flavor, it is cold in nature.Distributed in heart and lung channels.Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.In addition modern medicine finds lily Containing colchicin, there is anti-inflammatory analgetic to treatment gout.
The advantageous effect of the present invention compared with prior art is:
Particle pill is made using ten five tastes Chinese herbal medicines in the medicine pill of the treatment gout, is made using the comprehensive collaboration of various drugs With gout is treated, to human body Small side effects, without decoction, the feature for having therapy easy, cheap, significant in efficacy, The medicine pill of the treatment gout have clearing heat and expelling damp, promoting blood circulation and stopping pain, treating both manifestation and root cause of disease work(, treatment gout effective percentage up to 97% with On.
Specific embodiment
Weigh the bulk pharmaceutical chemicals in the various embodiments described above, then by ten five kinds of Chinese medicine such as above-mentioned rhizoma atractylodis, Radix Salviae Miltiorrhizae, coix seed, Cortex Phellodendri It adds water to cook three times, 1 hour every time, decocting liquid filtering, filtrate merges, and is concentrated into proportion 1.10~1.20(60℃), depressurize dry It is dry, crush, add suitable amount of sucrose powder, dextrin, it is dry, whole ball to get treatment gout pill;Finally it is distributed into bottle, 60 grams every bottle .
Usage and dosage:A bottle cap every time(6-10 grams), three times a day, take orally.7-10 days as a treatment course generally need two The course for the treatment of can suitably increase and decrease the course for the treatment of according to the state of an illness.
Points for attention:Pregnant woman uses with caution.
The effect of in order to illustrate the present invention to treatment gout, the present invention passes through has carried out clinical observation to 166 patients, Clinical data is as follows:
1, general data:166 patient with gout are out-patient, and male 87, women 79, the above case is by blood urine The judgement that acid is checked and made after physical examination in detail.
2, efficacy assessment standard:
The uric acid level of patient is compared.This experimental result is divided into about the evaluation criteria of gout curative effect according to Chinese medicine Three-level evaluation criteria:
In vain:Pretherapy and post-treatment patient does not have any improvement;
Effectively:Patient's cardinal symptom disappears substantially, but function of joint still has exception with main physical and chemical index;
It is effective:The symptom disappearance of patient, functional rehabilitation, physical and chemical index are normal after treatment.
Total effective rate=(effective+effectively)/total number of cases × 100%.
Model case one:
Old gout case Lee, man, 70 years old.Body is hale and hearty, and body is partially thin, spirit.Patient has gout medical history for many years.Right heel Local skin ulceration 3 years, the surface of a wound does not recover for a long time.Pain after on foot.Right heel festers once pitting, about 2 × 4cm, the surface of a wound Granulation tissue is stale, and purulent secretion is few, and arteria dorsalis pedis, posterior tibial artery beating are weak, and toes joint has deformed, skin-nourishing Difference, dry, furfur.Slightly edema.600 umol/L or more of uric acid.131 umol/L of creatinine.Feel weak, uncomfortable in chest, dream of having palpitation More, stool is normal, two hand shakings.Auscultation:Bicuspid valve two level blowing murmur, tricuspid valve area of auscultation have noise.Heart murmur.Tongue Yellow and greasy fur.The medicine pill pain relief after two weeks for taking orally above-mentioned treatment gout, continued to take after two weeks without apparent pain, half a year Follow-up no relapse afterwards.
Model case two:
Zhang, man, 50 years old.Then the property walked pain 3 ~ 4 years, no redness and swelling of joints history also lose arthrocele to two knee joint of main suit.Nothing Chilly generates heat history, receive can, it is convenient to both normal.Previously there is pulmonary tuberculosis history, has fully recovered.17 1 hydroxycorticosteroids 5.7 milligrams/24 are small When, 17 12.85 milligrams of ketosteroids/24 hours, erythrocyte sedimentation rate 2ram/1 hours, liver function is normal, and blood picture is normal.10.7 milligrams of % of uric acid. Doctor trained in Western medicine is diagnosed as gout.The medicine pill pain relief after two weeks for taking orally above-mentioned treatment gout continues to take after two weeks without apparent Pain, follow-up no relapse after half a year.
The above is presently preferred embodiments of the present invention, and the example above illustrates that the substantive content not to the present invention is made Limitation in any form, technology of the person of an ordinary skill in the technical field after having read this specification according to the present invention Essence is to any simple modification or deformation made by the above specific implementation mode, and the technology contents possibly also with the disclosure above The equivalent embodiment for being changed or being modified to equivalent variations, in the range of still falling within technical solution of the present invention, without departing from The spirit and scope of the invention.

Claims (3)

1. a kind of medicine pill for treating gout, which is characterized in that it is made of the raw material of following weight parts:(Unit:Part)
Cortex Phellodendri 5-15 rhizoma atractylodis 5-15 coix seeds 10-20
Radix cyathulae 10-20 Radix Salviae Miltiorrhizae 10-20 Radix Curcumaes 5-15
Corydalis tuber 10-20 radix paeoniae rubra 10-20 Caulis Spatholobis 10-20
Umbellate pore furgus 10-20 rhizoma alismatis 5-15 Asiatic plantains 10-20
Dandelion 20-30 dried orange peel 5-15 lilies 7-17;
In above-mentioned prescription, Cortex Phellodendri, rhizoma atractylodis, coix seed, radix cyathulae are monarch drug in a prescription;Radix Salviae Miltiorrhizae, Radix Curcumae, corydalis tuber, radix paeoniae rubra, Caulis Spatholobi are minister Medicine, umbellate pore furgus, rhizoma alismatis, Asiatic plantain, dandelion are adjutant, and dried orange peel, lily are to make medicine, preferably reach clearing damp with the cooperation of other Chinese medicines Work(.
2. a kind of medicine pill for treating gout according to claim 1, it is characterised in that:It by following weight parts original Material is made:(Unit:Part)
Cortex Phellodendri 7-12 rhizoma atractylodis 7-12 coix seeds 12-17
Radix cyathulae 12-17 Radix Salviae Miltiorrhizae 12-17 Radix Curcumaes 7-12
Corydalis tuber 12-17 radix paeoniae rubra 12-17 Caulis Spatholobis 12-17
Umbellate pore furgus 12-17 rhizoma alismatis 7-12 Asiatic plantains 12-17
Dandelion 22-27 dried orange peel 7-12 lilies 9-15.
3. a kind of medicine pill for treating gout according to claim 1, it is characterised in that:It by following weight parts original Material is made:(Unit:Part)
10 rhizoma atractylodis of Cortex Phellodendri, 10 coix seed 15
15 Radix Salviae Miltiorrhizae of radix cyathulae, 15 Radix Curcumae 10
15 radix paeoniae rubra of corydalis tuber, 15 Caulis Spatholobi 15
15 rhizoma alismatis of umbellate pore furgus, 10 Asiatic plantain 15
25 dried orange peel of dandelion, 10 lily 12.
CN201810937867.8A 2018-08-17 2018-08-17 A kind of medicine pill for treating gout Pending CN108704108A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906289A (en) * 2015-06-12 2015-09-16 公安县中医医院 Traditional Chinese medicine pill for treating chronic obstructive pulmonary disease
CN110151933A (en) * 2019-06-27 2019-08-23 眉山市中医医院(眉山市东坡区人民医院) A kind of Chinese medicine composition and preparation method thereof for treating gout
CN113713060A (en) * 2021-10-25 2021-11-30 陕西省中医医院 Blood stasis removing and turbidity lowering prescription for treating gout

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CN104524419A (en) * 2015-01-16 2015-04-22 邓运明 Traditional Chinese medicine preparation for treating gout

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JPS5555185A (en) * 1978-10-03 1980-04-22 Nippon Shinyaku Co Ltd Extracting method of picrasma quassioides benn.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906289A (en) * 2015-06-12 2015-09-16 公安县中医医院 Traditional Chinese medicine pill for treating chronic obstructive pulmonary disease
CN110151933A (en) * 2019-06-27 2019-08-23 眉山市中医医院(眉山市东坡区人民医院) A kind of Chinese medicine composition and preparation method thereof for treating gout
CN113713060A (en) * 2021-10-25 2021-11-30 陕西省中医医院 Blood stasis removing and turbidity lowering prescription for treating gout
CN113713060B (en) * 2021-10-25 2022-07-05 陕西省中医医院 Blood stasis removing and turbidity lowering prescription for treating gout

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Application publication date: 20181026